Julia Gorelik - Publications

Affiliations: 
National Heart and Lung Institute Imperial College London, London, England, United Kingdom 

154 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Williams ZJ, Alvarez-Laviada A, Hoagland D, Jourdan LJ, Poelzing S, Gorelik J, Gourdie RG. Development and characterization of the mode-of-action of inhibitory and agonist peptides targeting the voltage-gated sodium channel SCN1B beta-subunit. Journal of Molecular and Cellular Cardiology. 194: 32-45. PMID 38942073 DOI: 10.1016/j.yjmcc.2024.06.008  0.718
2023 Glukhov AV, Gorelik J. Mind the Gap: Does Junctophilin 2 Gear the Coupled-Clock System in Pacemaker Cardiomyocytes? Jacc. Basic to Translational Science. 8: 1589-1591. PMID 38205355 DOI: 10.1016/j.jacbts.2023.09.015  0.723
2023 Judina A, Niglas M, Leonov V, Kirkby NS, Diakonov I, Wright PT, Zhao L, Mitchell JA, Gorelik J. Pulmonary Hypertension-Associated Right Ventricular Cardiomyocyte Remodelling Reduces Treprostinil Function. Cells. 12. PMID 38067192 DOI: 10.3390/cells12232764  0.767
2023 Song Q, Alvarez-Laviada A, Schrup SE, Reilly-O'Donnell B, Entcheva E, Gorelik J. Opto-SICM framework combines optogenetics with scanning ion conductance microscopy for probing cell-to-cell contacts. Communications Biology. 6: 1131. PMID 37938652 DOI: 10.1038/s42003-023-05509-3  0.803
2023 Kwan Z, Nadappuram BP, Leung MM, Kondrashov A, Mohagaonkar S, Li A, Amaradasa KS, Chen J, Rothery S, Kibreab I, Fu J, Sanchez-Alonso JL, Mansfield CA, Subramanian H, Wright PT, ... ... Gorelik J, et al. Microtubule-Mediated Regulation of βAR Translation and Function in Failing Hearts. Circulation Research. PMID 37869877 DOI: 10.1161/CIRCRESAHA.123.323174  0.812
2023 Medvedev RY, Turner DGP, DeGuire FC, Leonov V, Lang D, Gorelik J, Alvarado FJ, Bondarenko VE, Glukhov AV. Caveolae-associated cAMP/Ca-mediated mechano-chemical signal transduction in mouse atrial myocytes. Journal of Molecular and Cellular Cardiology. 184: 75-87. PMID 37805125 DOI: 10.1016/j.yjmcc.2023.10.004  0.813
2023 Koch C, Reilly-O'Donnell B, Gutierrez R, Lucarelli C, Ng FS, Gorelik J, Ivanov AP, Edel JB. Nanopore sequencing of DNA-barcoded probes for highly multiplexed detection of microRNA, proteins and small biomarkers. Nature Nanotechnology. PMID 37749222 DOI: 10.1038/s41565-023-01479-z  0.763
2023 Sanchez-Alonso JL, Fedele L, Copier JS, Lucarelli C, Mansfield C, Judina A, Houser SR, Brand T, Gorelik J. Functional LTCC-βAR Complex Needs Caveolin-3 and Is Disrupted in Heart Failure. Circulation Research. PMID 37313722 DOI: 10.1161/CIRCRESAHA.123.322508  0.809
2023 Markandeya YS, Gregorich ZR, Feng L, Ramchandran V, O' Hara T, Vaidyanathan R, Mansfield C, Keefe AM, Beglinger CJ, Best JM, Kalscheur MM, Lea MR, Hacker TA, Gorelik J, Trayanova NA, et al. Caveolin-3 and Caveolae regulate ventricular repolarization. Journal of Molecular and Cellular Cardiology. PMID 36842733 DOI: 10.1016/j.yjmcc.2023.02.005  0.734
2023 Sharma A, Rahman G, Gorelik J, Bhargava A. Voltage-Gated T-Type Calcium Channel Modulation by Kinases and Phosphatases: The Old Ones, the New Ones, and the Missing Ones. Cells. 12. PMID 36766802 DOI: 10.3390/cells12030461  0.739
2022 Francis AJ, Firth JM, Sanchez-Alonso JL, Gorelik J, MacLeod KT. GPER limits adverse changes to Ca signalling and arrhythmogenic activity in ovariectomised guinea pig cardiomyocytes. Frontiers in Physiology. 13: 1023755. PMID 36439245 DOI: 10.3389/fphys.2022.1023755  0.737
2022 Faleeva M, Diakonov I, Srivastava P, Ramuz M, Calamera G, Andressen KW, Bork N, Tsansizi L, Cosson MV, Bernardo AS, Nikolaev V, Gorelik J. Compartmentation of cGMP Signaling in Induced Pluripotent Stem Cell Derived Cardiomyocytes during Prolonged Culture. Cells. 11. PMID 36291124 DOI: 10.3390/cells11203257  0.653
2022 Wright P, Gorelik J. Junctophillin-2: Coupling Hopes for Cardiac Gene Therapy to Gene Transcription. Circulation Research. 130: 1318-1320. PMID 35482830 DOI: 10.1161/CIRCRESAHA.122.321066  0.561
2022 Dokshokova L, Franzoso M, Di Bona A, Moro N, Sanchez Alonso JL, Prando V, Sandre M, Basso C, Faggian G, Abriel H, Marin O, Gorelik J, Zaglia T, Mongillo M. Nerve growth factor transfer from cardiomyocytes to innervating sympathetic neurons activates TrkA receptors at the neuro-cardiac junction. The Journal of Physiology. PMID 35413134 DOI: 10.1113/JP282828  0.614
2022 Nunez-Toldra R, Kirwin T, Ferraro E, Pitoulis FG, Nicastro L, Bardi I, Kit-Anan W, Gorelik J, Simon AR, Terracciano CM. Mechanosensitive molecular mechanisms of myocardial fibrosis in living myocardial slices. Esc Heart Failure. 9: 1400-1412. PMID 35128823 DOI: 10.1002/ehf2.13832  0.689
2021 Wright PT, Gorelik J, Harding SE. Electrophysiological Remodeling: Cardiac T-Tubules and ß-Adrenoceptors. Cells. 10. PMID 34572106 DOI: 10.3390/cells10092456  0.762
2021 Medvedev RY, Sanchez-Alonso JL, Mansfield CA, Judina A, Francis AJ, Pagiatakis C, Trayanova N, Glukhov AV, Miragoli M, Faggian G, Gorelik J. Local hyperactivation of L-type Ca channels increases spontaneous Ca release activity and cellular hypertrophy in right ventricular myocytes from heart failure rats. Scientific Reports. 11: 4840. PMID 33649357 DOI: 10.1038/s41598-021-84275-w  0.816
2021 Medvedev R, Sanchez-Alonso JL, Alvarez-Laviada A, Rossi S, Dries E, Schorn T, Abdul-Salam VB, Trayanova N, Wojciak-Stothard B, Miragoli M, Faggian G, Gorelik J. Nanoscale Study of Calcium Handling Remodeling in Right Ventricular Cardiomyocytes Following Pulmonary Hypertension. Hypertension (Dallas, Tex. : 1979). 77: 605-616. PMID 33356404 DOI: 10.1161/HYPERTENSIONAHA.120.14858  0.8
2021 Kondrashov A, Mohd Yusof NAN, Hasan A, Goulding J, Kodagoda T, Hoang DM, Vo NTN, Melarangi T, Dolatshad N, Gorelik J, Hill SJ, Harding SE, Denning C. CRISPR/Cas9-mediated generation and analysis of N terminus polymorphic models of βAR in isogenic hPSC-derived cardiomyocytes. Molecular Therapy. Methods & Clinical Development. 20: 39-53. PMID 33335946 DOI: 10.1016/j.omtm.2020.10.019  0.607
2020 Vasavan T, Deepak S, Jayawardane IA, Lucchini M, Martin C, Geenes V, Yang J, Lövgren-Sandblom A, Seed PT, Chambers J, Stone S, Kurlak L, Dixon PH, Marschall HU, Gorelik J, et al. Fetal cardiac dysfunction in intrahepatic cholestasis of pregnancy is associated with elevated serum bile acid concentrations. Journal of Hepatology. PMID 33276032 DOI: 10.1016/j.jhep.2020.11.038  0.62
2020 Gross P, Johnson J, Romero CM, Eaton DM, Poulet C, Sanchez-Alonso JL, Lucarelli C, Ross J, Gibb AA, Garbincius JF, Lambert J, Varol E, Yang Y, Wallner M, Feldsott EA, ... ... Gorelik J, et al. Interaction of the Joining Region in Junctophilin-2 with the L-type Ca Channel Is Pivotal for Cardiac Dyad Assembly and Intracellular Ca Dynamics. Circulation Research. PMID 33092464 DOI: 10.1161/CIRCRESAHA.119.315715  0.741
2020 Hasan A, Mohammadi N, Nawaz A, Kodagoda T, Diakonov I, Harding SE, Gorelik J. Age-Dependent Maturation of iPSC-CMs Leads to the Enhanced Compartmentation of βAR-cAMP Signalling. Cells. 9. PMID 33053822 DOI: 10.3390/cells9102275  0.636
2020 Ferraro E, Pozhidaeva L, Pitcher DS, Mansfield C, Koh JHB, Williamson C, Aslanidi O, Gorelik J, Ng FS. Prolonged ursodeoxycholic acid administration reduces acute ischaemia-induced arrhythmias in adult rat hearts. Scientific Reports. 10: 15284. PMID 32943714 DOI: 10.1038/S41598-020-72016-4  0.798
2020 Sintou A, Mansfield C, Iacob A, Chowdhury RA, Narodden S, Rothery SM, Podovei R, Sanchez-Alonso JL, Ferraro E, Swiatlowska P, Harding SE, Prasad S, Rosenthal N, Gorelik J, Sattler S. Mediastinal Lymphadenopathy, Class-Switched Auto-Antibodies and Myocardial Immune-Complexes During Heart Failure in Rodents and Humans. Frontiers in Cell and Developmental Biology. 8: 695. PMID 32850816 DOI: 10.3389/Fcell.2020.00695  0.805
2020 Swiatlowska P, Sanchez-Alonso JL, Mansfield C, Scaini D, Korchev Y, Novak P, Gorelik J. Short-term angiotensin II treatment regulates cardiac nanomechanics via microtubule modifications. Nanoscale. 12: 16315-16329. PMID 32720664 DOI: 10.1039/D0Nr02474K  0.818
2020 Sanchez-Alonso JL, Loucks A, Schobesberger S, van Cromvoirt AM, Poulet C, Chowdhury RA, Trayanova N, Gorelik J. Nanoscale regulation of L-type calcium channels differentiates between ischemic and dilated cardiomyopathies. Ebiomedicine. 57: 102845. PMID 32580140 DOI: 10.1016/J.Ebiom.2020.102845  0.809
2020 Lang D, Calaghan SC, Gorelik J, Glukhov AV. Editorial: Cardiomyocyte Microdomains: An Emerging Concept of Local Regulation and Remodeling. Frontiers in Physiology. 11: 512. PMID 32574239 DOI: 10.3389/Fphys.2020.00512  0.783
2020 Rifai SE, Sintou A, Mansfield C, Houston C, Chowdhury RA, Gorelik J, Sattler S. Humoral factors in serum of rats with chronic heart failure induce cardiomyocyte hypertrophy and reduce viability. Clinical Medicine (London, England). 20: s107. PMID 32409411 DOI: 10.7861/Clinmed.20-2-S107  0.73
2020 Schobesberger S, Wright PT, Poulet C, Sanchez Alonso Mardones JL, Mansfield C, Friebe A, Harding SE, Balligand JL, Nikolaev VO, Gorelik J. β-Adrenoceptor redistribution impairs NO/cGMP/PDE2 signalling in failing cardiomyocytes. Elife. 9. PMID 32228862 DOI: 10.7554/Elife.52221  0.806
2020 Tikhomirov R, Donnell BR, Catapano F, Faggian G, Gorelik J, Martelli F, Emanueli C. Exosomes: From Potential Culprits to New Therapeutic Promise in the Setting of Cardiac Fibrosis. Cells. 9. PMID 32131460 DOI: 10.3390/Cells9030592  0.649
2020 Judina A, Gorelik J, Wright PT. Studying signal compartmentation in adult cardiomyocytes. Biochemical Society Transactions. 48: 61-70. PMID 32104883 DOI: 10.1042/Bst20190247  0.678
2020 Poulet C, Sanchez-Alonso J, Swiatlowska P, Mouy F, Lucarelli C, Alvarez-Laviada A, Gross P, Terracciano C, Houser S, Gorelik J. Junctophilin-2 tethers T-tubules and recruits functional L-type calcium channels to lipid rafts in adult cardiomyocytes. Cardiovascular Research. PMID 32053184 DOI: 10.1093/Cvr/Cvaa033  0.808
2020 Swiatlowska P, Sanchez-Alonso JL, Wright PT, Novak P, Gorelik J. Microtubules regulate cardiomyocyte transversal Young's modulus. Proceedings of the National Academy of Sciences of the United States of America. PMID 31988123 DOI: 10.1073/Pnas.1917171117  0.806
2020 Yang HQ, Pérez-Hernández M, Sanchez-Alonso J, Shevchuk A, Gorelik J, Rothenberg E, Delmar M, Coetzee WA. Ankyrin-G mediates targeting of both Na and K channels to the rat cardiac intercalated disc. Elife. 9. PMID 31934859 DOI: 10.7554/Elife.52373  0.313
2020 Schobesberger S, Wright PT, Poulet C, Mardones JLSA, Mansfield C, Friebe A, Harding SE, Balligand J, Nikolaev VO, Gorelik J. Author response: β3-Adrenoceptor redistribution impairs NO/cGMP/PDE2 signalling in failing cardiomyocytes Elife. DOI: 10.7554/Elife.52221.Sa2  0.768
2020 Francis A, Firth J, Islam N, Gorelik J, MacLeod K. The effect of oestrogen withdrawal on cardiac Ca2+ regulation and the influence of GPER1 European Heart Journal. 41. DOI: 10.1093/ehjci/ehaa946.3599  0.739
2020 Francis AJ, Firth JM, Islam N, Gorelik J, Macleod KT. The Effect of Oestrogen Withdrawal on Ca2+ Regulation and the Influence of GPER1 Biophysical Journal. 118: 403a-404a. DOI: 10.1016/J.Bpj.2019.11.2290  0.692
2020 Yang H, Pérez-Hernández M, Sanchez-Alonso JL, Shevchuk A, Gorelik J, Rothenberg E, Delmar M, Coetzee WA. Ankyrin-G Mediates Targeting of both Na+ and KATP Channels to the Cardiac Intercalated Disc Biophysical Journal. 118: 270a. DOI: 10.1016/J.Bpj.2019.11.1556  0.333
2019 Ramuz M, Hasan A, Gruscheski L, Diakonov I, Pavlaki N, Nikolaev VO, Harding S, Dunsby C, Gorelik J. A Software Tool for High-Throughput Real-Time Measurement of Intensity-Based Ratio-Metric FRET. Cells. 8. PMID 31795419 DOI: 10.3390/Cells8121541  0.763
2019 Brezovjakova H, Tomlinson C, Mohd Naim N, Swiatlowska P, Erasmus JC, Huveneers S, Gorelik J, Bruche S, Braga VM. Junction Mapper is a novel computer vision tool to decipher cell-cell contact phenotypes. Elife. 8. PMID 31793877 DOI: 10.7554/Elife.45413  0.747
2019 Schultz F, Swiatlowska P, Alvarez-Laviada A, Sanchez-Alonso JL, Song Q, de Vries AAF, Pijnappels DA, Ongstad E, Braga VMM, Entcheva E, Gourdie RG, Miragoli M, Gorelik J. Cardiomyocyte-myofibroblast contact dynamism is modulated by connexin-43. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201802740RR. PMID 31253057 DOI: 10.1096/Fj.201802740Rr  0.786
2019 Ali T, Bednarska J, Vassilopoulos S, Tran M, Diakonov IA, Ziyadeh-Isleem A, Guicheney P, Gorelik J, Korchev YE, Reilly MM, Bitoun M, Shevchuk A. Correlative SICM-FCM reveals changes in morphology and kinetics of endocytic pits induced by disease-associated mutations in dynamin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201802635R. PMID 31017801 DOI: 10.1096/Fj.201802635R  0.729
2019 Yang H, Pérez-Hernández M, Sanchez-Alonso J, Shevchuk A, Gorelik J, Rothenberg E, Delmar M, Coetzee WA. Author response: Ankyrin-G mediates targeting of both Na+ and KATP channels to the rat cardiac intercalated disc Elife. DOI: 10.7554/Elife.52373.Sa2  0.336
2019 Brezovjakova H, Tomlinson C, Naim NM, Swiatlowska P, Erasmus JC, Huveneers S, Gorelik J, Bruche S, Braga VM. Author response: Junction Mapper is a novel computer vision tool to decipher cell–cell contact phenotypes Elife. DOI: 10.7554/Elife.45413.Sa2  0.714
2018 Wright PT, Sanchez-Alonso JL, Lucarelli C, Alvarez-Laviada A, Poulet CE, Bello SO, Faggian G, Terracciano CM, Gorelik J. Partial Mechanical Unloading of the Heart Disrupts L-Type Calcium Channel and Beta-Adrenoceptor Signaling Microdomains. Frontiers in Physiology. 9: 1302. PMID 30283354 DOI: 10.3389/Fphys.2018.01302  0.794
2018 Bastug-Özel Z, Wright PT, Kraft AE, Pavlovic D, Howie J, Froese A, Fuller W, Gorelik J, Shattock MJ, Nikolaev VO. Heart failure leads to altered β2-adrenoceptor/cAMP dynamics in the sarcolemmal phospholemman/Na,K ATPase microdomain: Bastug et al. Phospholemman cAMP microdomain. Cardiovascular Research. PMID 30165515 DOI: 10.1093/Cvr/Cvy221  0.819
2018 Veeraraghavan R, Hoeker GS, Alvarez-Laviada A, Hoagland D, Wan X, King DR, Sanchez-Alonso J, Chen C, Jourdan J, Isom LL, Deschenes I, Smyth J, Gorelik J, Poelzing S, Gourdie RG. The adhesion function of the sodium channel beta subunit (β1) contributes to cardiac action potential propagation. Elife. 7. PMID 30106376 DOI: 10.7554/Elife.37610  0.758
2018 Subramanian H, Froese A, Jönsson P, Schmidt H, Gorelik J, Nikolaev VO. Distinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP. Nature Communications. 9: 2446. PMID 29934640 DOI: 10.1038/S41467-018-04891-5  0.714
2018 Bhogal NK, Hasan A, Gorelik J. The Development of Compartmentation of cAMP Signaling in Cardiomyocytes: The Role of T-Tubules and Caveolae Microdomains. Journal of Cardiovascular Development and Disease. 5. PMID 29751502 DOI: 10.3390/Jcdd5020025  0.694
2018 Ibrahim E, Diakonov I, Arunthavarajah D, Swift T, Goodwin M, McIlvride S, Nikolova V, Williamson C, Gorelik J. Bile acids and their respective conjugates elicit different responses in neonatal cardiomyocytes: role of Gi protein, muscarinic receptors and TGR5. Scientific Reports. 8: 7110. PMID 29740092 DOI: 10.1038/S41598-018-25569-4  0.799
2018 Wright PT, Bhogal NK, Diakonov I, Pannell LMK, Perera RK, Bork NI, Schobesberger S, Lucarelli C, Faggian G, Alvarez-Laviada A, Zaccolo M, Kamp TJ, Balijepalli RC, Lyon AR, Harding SE, ... ... Gorelik J, et al. Cardiomyocyte Membrane Structure and cAMP Compartmentation Produce Anatomical Variation in βAR-cAMP Responsiveness in Murine Hearts. Cell Reports. 23: 459-469. PMID 29642004 DOI: 10.1016/J.Celrep.2018.03.053  0.816
2018 Vasavan T, Ferraro E, Ibrahim E, Dixon P, Gorelik J, Williamson C. Heart and bile acids - Clinical consequences of altered bile acid metabolism. Biochimica Et Biophysica Acta. PMID 29317337 DOI: 10.1016/J.Bbadis.2017.12.039  0.793
2018 Veeraraghavan R, Hoeker GS, Alvarez-Laviada A, Hoagland D, Wan X, King DR, Sanchez-Alonso J, Chen C, Jourdan J, Isom LL, Deschenes I, Smyth JW, Gorelik J, Poelzing S, Gourdie RG. Author response: The adhesion function of the sodium channel beta subunit (β1) contributes to cardiac action potential propagation Elife. DOI: 10.7554/Elife.37610.025  0.743
2018 Medvedev R, Sanches-Alonso JL, Alvarez-Laviada A, Miragoli M, Faggian G, Gorelik J. Right ventricular myocytes have less organised membrane structures and different localisation of L-type calcium channels compared to myocytes from the left ventricle Journal of Molecular and Cellular Cardiology. 120: 42. DOI: 10.1016/J.Yjmcc.2018.05.127  0.794
2018 Sanchez-Alonso JL, Schobesberger S, Poulet CE, Bhogal N, Chowdhury R, Gorelik J. Function of L-Type Calcium Channel Microdomain in Human Myocytes from Hearts with Ischemic versus Dilated Cardiomyopathies Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.3444  0.807
2018 Alvarez-Laviada A, Veeraraghavan R, Braga V, Gourdie R, Gorelik J. Dissecting Function and Distribution of Sodium Channels and GAP Junctional Proteins using Super-Resolution Patch-Clamp Biophysical Journal. 114: 202a-203a. DOI: 10.1016/J.Bpj.2017.11.1132  0.72
2017 Todd Milne G, Sandner P, Lincoln KA, Harrison PC, Chen H, Wang H, Clifford H, Qian HS, Wong D, Sarko C, Fryer R, Richman J, Reinhart GA, Boustany CM, Pullen SS, ... ... Gorelik J, et al. Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017. Bmc Pharmacology & Toxicology. 18: 64. PMID 29035170 DOI: 10.1186/s40360-017-0170-5  0.753
2017 Perbellini F, Watson SA, Scigliano M, Alayoubi S, Tkach S, Bardi I, Quaife N, Kane C, Dufton NP, Simon A, Sikkel MB, Faggian G, Randi AM, Gorelik J, Harding SE, et al. Investigation of cardiac fibroblasts using myocardial slices. Cardiovascular Research. PMID 29016704 DOI: 10.1093/Cvr/Cvx152  0.793
2017 Adeyemi O, Alvarez-Laviada A, Schultz F, Ibrahim E, Trauner M, Williamson C, Glukhov AV, Gorelik J. Ursodeoxycholic acid prevents ventricular conduction slowing and arrhythmia by restoring T-type calcium current in fetuses during cholestasis. Plos One. 12: e0183167. PMID 28934223 DOI: 10.1371/Journal.Pone.0183167  0.797
2017 Schobesberger S, Wright P, Tokar S, Bhargava A, Mansfield C, Glukhov AV, Poulet C, Buzuk A, Monszpart A, Sikkel M, Harding SE, Nikolaev VO, Lyon AR, Gorelik J. T-tubule remodelling disturbs localised β2-adrenergic signalling in rat ventricular myocyte during the progression of heart failure. Cardiovascular Research. PMID 28505272 DOI: 10.1093/Cvr/Cvx074  0.809
2017 Surdo NC, Berrera M, Koschinski A, Brescia M, Machado MR, Carr C, Wright P, Gorelik J, Morotti S, Grandi E, Bers DM, Pantano S, Zaccolo M. FRET biosensor uncovers cAMP nano-domains at β-adrenergic targets that dictate precise tuning of cardiac contractility. Nature Communications. 8: 15031. PMID 28425435 DOI: 10.1038/Ncomms15031  0.678
2017 Veeraraghavan R, Hoeker GS, Alvarez Laviada A, Wan X, Deschenes I, Smyth J, Gorelik J, Poelzing S, Gourdie RG. STORM and TEM Identify the Cardiac Ephapse: An Intercalated Disk Nanodomain with Previously Unanticipated Functions in Cardiac Conduction Microscopy and Microanalysis. 23: 1110-1111. DOI: 10.1017/S1431927617006213  0.365
2016 Sanchez-Alonso JL, Bhargava A, O'Hara T, Glukhov AV, Schobesberger S, Bhogal NK, Sikkel MB, Mansfield C, Korchev YE, Lyon AR, Punjabi PP, Nikolaev VO, Trayanova NA, Gorelik J. Microdomain-Specific Modulation of L-type Calcium Channels Leads to Triggered Ventricular Arrhythmia in Heart Failure. Circulation Research. PMID 27572487 DOI: 10.1161/Circresaha.116.308698  0.816
2016 Shevchuk A, Tokar S, Gopal S, Sanchez-Alonso JL, Tarasov AI, Vélez-Ortega AC, Chiappini C, Rorsman P, Stevens MM, Gorelik J, Frolenkov GI, Klenerman D, Korchev YE. Angular Approach Scanning Ion Conductance Microscopy. Biophysical Journal. 110: 2252-2265. PMID 27224490 DOI: 10.1016/J.Bpj.2016.04.017  0.795
2016 Trantidou T, Humphrey EJ, Poulet C, Gorelik J, Prodromakis T, Terracciano CM. Surface Chemistry and Microtopography of Parylene C Films Control the Morphology and Microtubule Density of Cardiac Myocytes. Tissue Engineering. Part C, Methods. 22: 464-72. PMID 27018760 DOI: 10.1089/Ten.Tec.2015.0581  0.799
2016 Leo-Macias A, Agullo-Pascual E, Sanchez-Alonso JL, Keegan S, Lin X, Arcos T, Feng-Xia-Liang, Korchev YE, Gorelik J, Fenyö D, Rothenberg E, Delmar M. Erratum: Nanoscale visualization of functional adhesion/excitability nodes at the intercalated disc. Nature Communications. 7: 10919. PMID 26899761 DOI: 10.1038/ncomms10919  0.457
2016 Zhang Y, Clausmeyer J, Babakinejad B, López Córdoba A, Ali T, Shevchuk A, Takahashi Y, Novak P, Edwards C, Lab M, Gopal S, Chiappini C, Anand U, Magnani L, Coombes C, ... Gorelik J, et al. Spearhead Nanometric Field-Effect Transistor Sensors for Single-Cell Analysis. Acs Nano. PMID 26816294 DOI: 10.1021/Acsnano.5B05211  0.783
2016 Leo-Macias A, Agullo-Pascual E, Sanchez-Alonso JL, Keegan S, Lin X, Arcos T, Feng-Xia-Liang, Korchev YE, Gorelik J, Fenyö D, Rothenberg E, Delmar M. Nanoscale visualization of functional adhesion/excitability nodes at the intercalated disc. Nature Communications. 7: 10342. PMID 26787348 DOI: 10.1038/Ncomms10342  0.584
2016 Schultz F, Hasan A, Alvarez-Laviada A, Miragoli M, Bhogal N, Wells S, Poulet C, Chambers J, Williamson C, Gorelik J. The protective effect of ursodeoxycholic acid in an in vitro model of the human fetal heart occurs via targeting cardiac fibroblasts. Progress in Biophysics and Molecular Biology. 120: 149-63. PMID 26777584 DOI: 10.1016/J.Pbiomolbio.2016.01.003  0.812
2016 Schobesberger S, Jönsson P, Buzuk A, Korchev Y, Siggers J, Gorelik J. Nanoscale, Voltage-Driven Application of Bioactive Substances onto Cells with Organized Topography. Biophysical Journal. 110: 141-6. PMID 26745417 DOI: 10.1016/J.Bpj.2015.11.017  0.8
2016 Dubuis E, Wrench C, Dekkak B, Shala F, Shaifta Y, Ward J, Gorelik J, Belvisi M, Birrell M. Central role of AC6 in β2 agonist induced relaxation of human airway smooth muscle European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Oa3308  0.31
2016 Glukhov AV, Balycheva M, Sanchez-Alonso JL, Bhogal N, Diakonov I, Mazzola M, Faggian G, Gorelik J. Microdomain-Specific Remodelling of Autonomic Regulation of L-Type Calcium Channels Revealed by Super-Resolution Scanning Patch Clamp in Rat Atrial Myocytes in Heart Failure Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.2416  0.819
2015 Balycheva M, Faggian G, Glukhov AV, Gorelik J. Microdomain-specific localization of functional ion channels in cardiomyocytes: an emerging concept of local regulation and remodelling. Biophysical Reviews. 7: 43-62. PMID 28509981 DOI: 10.1007/S12551-014-0159-X  0.826
2015 Miragoli M, Sanchez-Alonso JL, Bhargava A, Wright PT, Sikkel M, Schobesberger S, Diakonov I, Novak P, Castaldi A, Cattaneo P, Lyon AR, Lab MJ, Gorelik J. Microtubule-Dependent Mitochondria Alignment Regulates Calcium Release in Response to Nanomechanical Stimulus in Heart Myocytes. Cell Reports. PMID 26725114 DOI: 10.1016/J.Celrep.2015.12.014  0.806
2015 Shigeto M, Ramracheya R, Tarasov AI, Cha CY, Chibalina MV, Hastoy B, Philippaert K, Reinbothe T, Rorsman N, Salehi A, Sones WR, Vergari E, Weston C, Gorelik J, Katsura M, et al. GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation. The Journal of Clinical Investigation. PMID 26571400 DOI: 10.1172/Jci81975  0.663
2015 Glukhov AV, Balycheva M, Sanchez-Alonso JL, Ilkan Z, Alvarez-Laviada A, Bhogal N, Diakonov I, Schobesberger S, Sikkel MB, Bhargava A, Faggian G, Punjabi PP, Houser SR, Gorelik J. Direct Evidence for Microdomain-Specific Localization and Remodeling of Functional L-Type Calcium Channels in Rat and Human Atrial Myocytes. Circulation. 132: 2372-84. PMID 26450916 DOI: 10.1161/Circulationaha.115.018131  0.798
2015 Wright PT, Schobesberger S, Gorelik J. Studying GPCR/cAMP pharmacology from the perspective of cellular structure. Frontiers in Pharmacology. 6: 148. PMID 26236239 DOI: 10.3389/Fphar.2015.00148  0.793
2015 Mazzola M, Diakonov I, Miragoli M, Faggian G, Glukhov AV, Gorelik J. Inhibitory effects of adenosine and adenosine A1 receptors stimulation on catecholamine-induced increase in camp level and force of contraction in atrial and ventricular myocyte Vascular Pharmacology. 75: 62. DOI: 10.1016/J.Vph.2015.11.051  0.782
2015 Schultz F, Hasan A, Alvarez-Laviada A, Miragoli M, Bhogal N, Wells S, Poulet C, Chambers J, Williamson C, Gorelik J. The protective effect of ursodeoxycholic acid in an in vitro model of the human fetal heart occurs via targeting cardiac fibroblasts Progress in Biophysics and Molecular Biology. DOI: 10.1016/j.pbiomolbio.2016.01.003  0.798
2014 Hong T, Yang H, Zhang SS, Cho HC, Kalashnikova M, Sun B, Zhang H, Bhargava A, Grabe M, Olgin J, Gorelik J, Marbán E, Jan LY, Shaw RM. Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia. Nature Medicine. 20: 624-32. PMID 24836577 DOI: 10.1038/Nm.3543  0.774
2014 Miragoli M, Yacoub MH, El-Hamamsy I, Sanchez-Alonso JL, Moshkov A, Mongkoldhumrongkul N, Padala M, Paramagurunathan S, Sarathchandra P, Korchev YE, Gorelik J, Chester AH. Side-specific mechanical properties of valve endothelial cells. American Journal of Physiology. Heart and Circulatory Physiology. 307: H15-24. PMID 24791787 DOI: 10.1152/Ajpheart.00228.2013  0.788
2014 Götz KR, Sprenger JU, Perera RK, Steinbrecher JH, Lehnart SE, Kuhn M, Gorelik J, Balligand JL, Nikolaev VO. Transgenic mice for real-time visualization of cGMP in intact adult cardiomyocytes. Circulation Research. 114: 1235-45. PMID 24599804 DOI: 10.1161/Circresaha.114.302437  0.685
2014 Novak P, Shevchuk A, Ruenraroengsak P, Miragoli M, Thorley AJ, Klenerman D, Lab MJ, Tetley TD, Gorelik J, Korchev YE. Imaging single nanoparticle interactions with human lung cells using fast ion conductance microscopy. Nano Letters. 14: 1202-7. PMID 24555574 DOI: 10.1021/Nl404068P  0.778
2014 Wright PT, Nikolaev VO, O'Hara T, Diakonov I, Bhargava A, Tokar S, Schobesberger S, Shevchuk AI, Sikkel MB, Wilkinson R, Trayanova NA, Lyon AR, Harding SE, Gorelik J. Caveolin-3 regulates compartmentation of cardiomyocyte beta2-adrenergic receptor-mediated cAMP signaling. Journal of Molecular and Cellular Cardiology. 67: 38-48. PMID 24345421 DOI: 10.1016/J.Yjmcc.2013.12.003  0.808
2014 Miragoli M, Schultz F, Vite A, Pijnappels D, Lab M, Gorelik J. 296Connexin43 expression modulate myofibroblasts mechanical coupling: implication for the infarct borderzone expansion Cardiovascular Research. 103. DOI: 10.1093/Cvr/Cvu088.1  0.796
2014 Kane C, Dias P, Helen N, Trantidou T, Camelliti P, Gorelik J, Terracciano CM. 267Direct contact between human cardiac fibroblasts and human induced pluripotent stem cell-derived cardiomyocytes counteracts changes in calcium cycling induced by soluble mediators Cardiovascular Research. 103. DOI: 10.1093/Cvr/Cvu083.3  0.714
2013 Novak P, Gorelik J, Vivekananda U, Shevchuk AI, Ermolyuk YS, Bailey RJ, Bushby AJ, Moss GW, Rusakov DA, Klenerman D, Kullmann DM, Volynski KE, Korchev YE. Nanoscale-targeted patch-clamp recordings of functional presynaptic ion channels. Neuron. 79: 1067-77. PMID 24050398 DOI: 10.1016/J.Neuron.2013.07.012  0.79
2013 Bhargava A, Gorelik J. Recording single-channel currents using "smart patch-clamp" technique Methods in Molecular Biology. 998: 189-197. PMID 23529430 DOI: 10.1007/978-1-62703-351-0_14  0.769
2013 Bhargava A, Lin X, Novak P, Mehta K, Korchev Y, Delmar M, Gorelik J. Super-resolution scanning patch clamp reveals clustering of functional ion channels in adult ventricular myocyte. Circulation Research. 112: 1112-20. PMID 23438901 DOI: 10.1161/Circresaha.111.300445  0.797
2013 Gorelik J, Wright PT, Lyon AR, Harding SE. Spatial control of the βAR system in heart failure: the transverse tubule and beyond. Cardiovascular Research. 98: 216-24. PMID 23345264 DOI: 10.1093/Cvr/Cvt005  0.811
2013 Miragoli M, Novak P, Ruenraroengsak P, Shevchuk AI, Korchev YE, Lab MJ, Tetley TD, Gorelik J. Functional interaction between charged nanoparticles and cardiac tissue: a new paradigm for cardiac arrhythmia? Nanomedicine (London, England). 8: 725-37. PMID 23140503 DOI: 10.2217/Nnm.12.125  0.785
2013 Ibrahim M, Siedlecka U, Buyandelger B, Harada M, Rao C, Moshkov A, Bhargava A, Schneider M, Yacoub MH, Gorelik J, Knöll R, Terracciano CM. A critical role for Telethonin in regulating t-tubule structure and function in the mammalian heart. Human Molecular Genetics. 22: 372-83. PMID 23100327 DOI: 10.1093/Hmg/Dds434  0.806
2013 Lab MJ, Bhargava A, Wright PT, Gorelik J. The scanning ion conductance microscope for cellular physiology. American Journal of Physiology. Heart and Circulatory Physiology. 304: H1-11. PMID 23086993 DOI: 10.1152/Ajpheart.00499.2012  0.789
2013 Ibrahim M, Navaratnarajah M, Siedlecka U, Rao C, Dias P, Moshkov A, Gorelik J, Yacoub M, Terracciano C. Mechanical unloading reverses transverse tubule remodelling and normalises local calcium-induced calcium release in a rodent model of heart failure The Lancet. 381: S54. DOI: 10.1016/S0140-6736(13)60494-8  0.823
2012 Ibrahim M, Kukadia P, Siedlecka U, Cartledge JE, Navaratnarajah M, Tokar S, Van Doorn C, Tsang VT, Gorelik J, Yacoub MH, Terracciano CM. Cardiomyocyte Ca2+ handling and structure is regulated by degree and duration of mechanical load variation. Journal of Cellular and Molecular Medicine. 16: 2910-8. PMID 22862818 DOI: 10.1111/J.1582-4934.2012.01611.X  0.811
2012 Paur H, Wright PT, Sikkel MB, Tranter MH, Mansfield C, O'Gara P, Stuckey DJ, Nikolaev VO, Diakonov I, Pannell L, Gong H, Sun H, Peters NS, Petrou M, Zheng Z, ... Gorelik J, et al. High levels of circulating epinephrine trigger apical cardiodepression in a β2-adrenergic receptor/Gi-dependent manner: a new model of Takotsubo cardiomyopathy. Circulation. 126: 697-706. PMID 22732314 DOI: 10.1161/Circulationaha.112.111591  0.801
2012 Takahashi Y, Shevchuk AI, Novak P, Babakinejad B, Macpherson J, Unwin PR, Shiku H, Gorelik J, Klenerman D, Korchev YE, Matsue T. Topographical and electrochemical nanoscale imaging of living cells using voltage-switching mode scanning electrochemical microscopy. Proceedings of the National Academy of Sciences of the United States of America. 109: 11540-5. PMID 22611191 DOI: 10.1073/Pnas.1203570109  0.774
2012 Shevchuk AI, Novak P, Taylor M, Diakonov IA, Ziyadeh-Isleem A, Bitoun M, Guicheney P, Lab MJ, Gorelik J, Merrifield CJ, Klenerman D, Korchev YE. An alternative mechanism of clathrin-coated pit closure revealed by ion conductance microscopy. The Journal of Cell Biology. 197: 499-508. PMID 22564416 DOI: 10.1083/Jcb.201109130  0.789
2012 Ibrahim M, Navaratnarajah M, Siedlecka U, Rao C, Dias P, Moshkov AV, Gorelik J, Yacoub MH, Terracciano CM. Mechanical unloading reverses transverse tubule remodelling and normalizes local Ca(2+)-induced Ca(2+)release in a rodent model of heart failure. European Journal of Heart Failure. 14: 571-80. PMID 22467752 DOI: 10.1093/Eurjhf/Hfs038  0.808
2012 Lyon AR, Nikolaev VO, Miragoli M, Sikkel MB, Paur H, Benard L, Hulot JS, Kohlbrenner E, Hajjar RJ, Peters NS, Korchev YE, Macleod KT, Harding SE, Gorelik J. Plasticity of surface structures and β(2)-adrenergic receptor localization in failing ventricular cardiomyocytes during recovery from heart failure. Circulation. Heart Failure. 5: 357-65. PMID 22456061 DOI: 10.1161/Circheartfailure.111.964692  0.819
2012 Potter CMF, Schobesberger S, Lundberg MH, Weinberg PD, Mitchell JA, Gorelik J. Shape and compliance of endothelial cells after shear stress in vitro or from different aortic regions: Scanning ion conductance microscopy study Plos One. 7. PMID 22359578 DOI: 10.1371/Journal.Pone.0031228  0.776
2012 Ruenraroengsak P, Novak P, Berhanu D, Thorley AJ, Valsami-Jones E, Gorelik J, Korchev YE, Tetley TD. Respiratory epithelial cytotoxicity and membrane damage (holes) caused by amine-modified nanoparticles. Nanotoxicology. 6: 94-108. PMID 21352086 DOI: 10.3109/17435390.2011.558643  0.662
2012 Wright P, Pannell L, Nikolaev V, Lyon A, Harding S, Gorelik J. 16 Imaging Regional Differences in Beta-2 Adrenergic Receptor Function at The Cellular Level Heart. 98: A5.3-A5. DOI: 10.1136/Heartjnl-2012-302951.016  0.799
2012 Leone A, Aquila I, Vicinanza C, Iaconetti C, Bochicchio A, Ottolenghi S, Indolfi C, Nadal-Ginard B, Ellison GM, Torella D, Mias C, Genet G, Guilbeau-Frugier C, Pathak A, Senard JM, ... ... Gorelik J, ... ... Gorelik J, et al. Oral abstract presentations & Young Investigators Competition Cardiovascular Research. 93: S46-S51. DOI: 10.1093/Cvr/Cvr333  0.751
2011 Weber B, Schoenauer R, Papadopulos F, Modregger P, Peter S, Stampanoni M, Mauri A, Mazza E, Gorelik J, Agarkova I, Frese L, Breymann C, Kretschmar O, Hoerstrup SP. Engineering of living autologous human umbilical cord cell-based septal occluder membranes using composite PGA-P4HB matrices. Biomaterials. 32: 9630-41. PMID 21978890 DOI: 10.1016/J.Biomaterials.2011.07.070  0.3
2011 Miragoli M, Kadir SH, Sheppard MN, Salvarani N, Virta M, Wells S, Lab MJ, Nikolaev VO, Moshkov A, Hague WM, Rohr S, Williamson C, Gorelik J. A protective antiarrhythmic role of ursodeoxycholic acid in an in vitro rat model of the cholestatic fetal heart. Hepatology (Baltimore, Md.). 54: 1282-92. PMID 21809354 DOI: 10.1002/Hep.24492  0.82
2011 Ibrahim M, Gorelik J, Yacoub MH, Terracciano CM. The structure and function of cardiac t-tubules in health and disease. Proceedings. Biological Sciences / the Royal Society. 278: 2714-23. PMID 21697171 DOI: 10.1098/Rspb.2011.0624  0.814
2011 Williamson C, Miragoli M, Sheikh Abdul Kadir S, Abu-Hayyeh S, Papacleovoulou G, Geenes V, Gorelik J. Bile acid signaling in fetal tissues: implications for intrahepatic cholestasis of pregnancy. Digestive Diseases (Basel, Switzerland). 29: 58-61. PMID 21691106 DOI: 10.1159/000324130  0.781
2011 Shevchuk AI, Novak P, Takahashi Y, Clarke R, Miragoli M, Babakinejad B, Gorelik J, Korchev YE, Klenerman D. Realizing the biological and biomedical potential of nanoscale imaging using a pipette probe. Nanomedicine (London, England). 6: 565-75. PMID 21542692 DOI: 10.2217/Nnm.10.154  0.78
2011 Miragoli M, Moshkov A, Novak P, Shevchuk A, Nikolaev VO, El-Hamamsy I, Potter CM, Wright P, Kadir SH, Lyon AR, Mitchell JA, Chester AH, Klenerman D, Lab MJ, Korchev YE, ... ... Gorelik J, et al. Scanning ion conductance microscopy: a convergent high-resolution technology for multi-parametric analysis of living cardiovascular cells. Journal of the Royal Society, Interface / the Royal Society. 8: 913-25. PMID 21325316 DOI: 10.1098/Rsif.2010.0597  0.807
2011 Potter CMF, Lundberg MH, Harrington LS, Warboys CM, Warner TD, Berson RE, Moshkov AV, Gorelik J, Weinberg PD, Mitchell JA. Role of shear stress in endothelial cell morphology and expression of cyclooxygenase isoforms Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 384-391. PMID 21127291 DOI: 10.1161/Atvbaha.110.214031  0.784
2011 Földes G, Mioulane M, Wright JS, Liu AQ, Novak P, Merkely B, Gorelik J, Schneider MD, Ali NN, Harding SE. Modulation of human embryonic stem cell-derived cardiomyocyte growth: a testbed for studying human cardiac hypertrophy? Journal of Molecular and Cellular Cardiology. 50: 367-76. PMID 21047517 DOI: 10.1016/J.Yjmcc.2010.10.029  0.726
2010 Ibrahim M, Al Masri A, Navaratnarajah M, Siedlecka U, Soppa GK, Moshkov A, Al-Saud SA, Gorelik J, Yacoub MH, Terracciano CM. Prolonged mechanical unloading affects cardiomyocyte excitation-contraction coupling, transverse-tubule structure, and the cell surface. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 3321-9. PMID 20430793 DOI: 10.1096/Fj.10-156638  0.812
2010 Sheikh Abdul Kadir SH, Miragoli M, Abu-Hayyeh S, Moshkov AV, Xie Q, Keitel V, Nikolaev VO, Williamson C, Gorelik J. Bile acid-induced arrhythmia is mediated by muscarinic M2 receptors in neonatal rat cardiomyocytes. Plos One. 5: e9689. PMID 20300620 DOI: 10.1371/Journal.Pone.0009689  0.802
2010 Nikolaev VO, Moshkov A, Lyon AR, Miragoli M, Novak P, Paur H, Lohse MJ, Korchev YE, Harding SE, Gorelik J. Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation. Science (New York, N.Y.). 327: 1653-7. PMID 20185685 DOI: 10.1126/Science.1185988  0.818
2009 Abdul Kadir SH, Ali NN, Mioulane M, Brito-Martins M, Abu-Hayyeh S, Foldes G, Moshkov AV, Williamson C, Harding SE, Gorelik J. Embryonic stem cell-derived cardiomyocytes as a model to study fetal arrhythmia related to maternal disease. Journal of Cellular and Molecular Medicine. 13: 3730-41. PMID 19438812 DOI: 10.1111/J.1582-4934.2009.00741.X  0.798
2009 Lyon AR, MacLeod KT, Zhang Y, Garcia E, Kanda GK, Lab MJ, Korchev YE, Harding SE, Gorelik J. Loss of T-tubules and other changes to surface topography in ventricular myocytes from failing human and rat heart Proceedings of the National Academy of Sciences of the United States of America. 106: 6854-6859. PMID 19342485 DOI: 10.1073/Pnas.0809777106  0.828
2009 Novak P, Li C, Shevchuk AI, Stepanyan R, Caldwell M, Hughes S, Smart TG, Gorelik J, Ostanin VP, Lab MJ, Moss GW, Frolenkov GI, Klenerman D, Korchev YE. Nanoscale live-cell imaging using hopping probe ion conductance microscopy. Nature Methods. 6: 279-81. PMID 19252505 DOI: 10.1038/Nmeth.1306  0.793
2009 Novak P, Li C, Shevchuk AI, Stepanyan R, Caldwell M, Hughes S, Smart TG, Gorelik J, Ostanin VP, Lab MJ, Moss GWJ, Frolenkov GI, Klenerman D, Korchev YE. Erratum: Corrigendum: Nanoscale live-cell imaging using hopping probe ion conductance microscopy Nature Methods. 6: 935-935. DOI: 10.1038/Nmeth1209-935A  0.773
2009 Novak P, Li C, Shevchuk A, Stepanyan R, Caldwell M, Hughes S, Smart T, Gorelik J, Lab M, Moss G, Frolenkov G, Klenerman D, Korchev Y. Next Generation SICM Allows Nanoscale Imaging Of Biological Processes In Real-time Biophysical Journal. 96: 374a. DOI: 10.1016/J.Bpj.2008.12.2811  0.796
2008 Gorelik J, Ali NN, Sheikh Abdul Kadir SH, Lab M, Stojkovic P, Armstrong L, Sviderskaya EV, Negulyaev YA, Klenerman D, Bennett DC, Lako M, Harding SE, Stojkovic M, Korchev YE. Non-invasive imaging of stem cells by scanning ion conductance microscopy: future perspective. Tissue Engineering. Part C, Methods. 14: 311-8. PMID 19055357 DOI: 10.1089/Ten.Tec.2008.0058  0.794
2008 Kemp SJ, Thorley AJ, Gorelik J, Seckl MJ, O'Hare MJ, Arcaro A, Korchev Y, Goldstraw P, Tetley TD. Immortalization of human alveolar epithelial cells to investigate nanoparticle uptake. American Journal of Respiratory Cell and Molecular Biology. 39: 591-7. PMID 18539954 DOI: 10.1165/Rcmb.2007-0334Oc  0.57
2008 Sánchez D, Johnson N, Li C, Novak P, Rheinlaender J, Zhang Y, Anand U, Anand P, Gorelik J, Frolenkov GI, Benham C, Lab M, Ostanin VP, Schäffer TE, Klenerman D, et al. Noncontact measurement of the local mechanical properties of living cells using pressure applied via a pipette. Biophysical Journal. 95: 3017-27. PMID 18515369 DOI: 10.1529/Biophysj.108.129551  0.765
2008 Kadir SHS, Abu-Hayyeh S, Williamson C, Gorelik J. Mechanisms of bile acid signalling in cardiomyocytes Journal of Molecular and Cellular Cardiology. 44: 774-775. DOI: 10.1016/J.Yjmcc.2008.02.152  0.643
2008 Kadir SHSA, Ali NN, Abu-Hayyeh S, Harding SE, Williamson C, Gorelik J. The use of embryonic stem cell-derived cardiomyocytes as a model to study fetal arrhythmia related to maternal disease Journal of Molecular and Cellular Cardiology. 44: 774. DOI: 10.1016/J.Yjmcc.2008.02.151  0.753
2008 Lyon A, Gorelik J, Dubb S, Macleod K, Poole-Wilson P, Harding S. Surface morphology and calcium control in myocytes from a rat MI model of heart failure Journal of Molecular and Cellular Cardiology. 44: 750. DOI: 10.1016/J.Yjmcc.2008.02.094  0.808
2008 Zhang Y, Ma L, Xu B, Gorelik J, Klenerman D, Lab M, Edwards C, Korchev Y. PI3K-mediated epithelial sodium channel activity by regulating the apical membrane morphology of renal epithelial cells Ifmbe Proceedings. 19: 603-607. DOI: 10.1007/978-3-540-79039-6-151  0.687
2007 Zhang Y, Sanchez D, Gorelik J, Klenerman D, Lab M, Edwards C, Korchev Y. Basolateral P2X4-like receptors regulate the extracellular ATP-stimulated epithelial Na+ channel activity in renal epithelia. American Journal of Physiology. Renal Physiology. 292: F1734-40. PMID 17356127 DOI: 10.1152/Ajprenal.00382.2006  0.716
2007 Harding SE, Ali NN, Brito-Martins M, Gorelik J. The human embryonic stem cell-derived cardiomyocyte as a pharmacological model Pharmacology and Therapeutics. 113: 341-353. PMID 17081613 DOI: 10.1016/J.Pharmthera.2006.08.008  0.651
2007 Sánchez D, Anand U, Gorelik J, Benham CD, Bountra C, Lab M, Klenerman D, Birch R, Anand P, Korchev Y. Localized and non-contact mechanical stimulation of dorsal root ganglion sensory neurons using scanning ion conductance microscopy. Journal of Neuroscience Methods. 159: 26-34. PMID 16887195 DOI: 10.1016/J.Jneumeth.2006.06.018  0.731
2007 Gorelik J, Yang L, Zhang Y, Lab M, Korchev YE, Monte Fd, Harding SE. WITHDRAWN: A novel Z-groove index characterizing myocardial surface structure and its modification in failing human heart Journal of Molecular and Cellular Cardiology. 42. DOI: 10.1016/J.Yjmcc.2007.03.812  0.799
2006 Gorelik J, Yang LQ, Zhang Y, Lab M, Korchev Y, Harding SE. A novel Z-groove index characterizing myocardial surface structure Cardiovascular Research. 72: 422-429. PMID 17054929 DOI: 10.1016/J.Cardiores.2006.09.009  0.799
2006 Gorelik J, Ali NN, Shevchuk AI, Lab M, Williamson C, Harding SE, Korchev YE. Functional characterization of embryonic stem cell-derived cardiomyocytes using scanning ion conductance microscopy Tissue Engineering. 12: 657-664. PMID 16674281 DOI: 10.1089/Ten.2006.12.657  0.8
2006 Gorelik J, Patel P, Ng'andwe C, Vodyanoy I, Diakonov I, Lab M, Korchev Y, Williamson C. Basic science: Genes encoding bile acid, phospholipid and anion transporters are expressed in a human fetal cardiomyocyte culture British Journal of Obstetrics and Gynaecology. 113: 552-558. PMID 16637898 DOI: 10.1111/J.1471-0528.2006.00918.X  0.789
2006 Yang LQ, Gorelik J, Korchev Y, Harding SE. Increase in β1AR-Gi coupling after detubulation in rat ventricular myocytes Journal of Molecular and Cellular Cardiology. 40: 923-924. DOI: 10.1016/J.Yjmcc.2006.03.025  0.722
2005 Gorelik J, Zhang Y, Sánchez D, Shevchuk A, Frolenkov G, Lab M, Klenerman D, Edwards C, Korchev Y. Aldosterone acts via an ATP autocrine/paracrine system: the Edelman ATP hypothesis revisited. Proceedings of the National Academy of Sciences of the United States of America. 102: 15000-5. PMID 16230642 DOI: 10.1073/Pnas.0507008102  0.799
2005 Ying L, Bruckbauer A, Zhou D, Gorelik J, Shevchuk A, Lab M, Korchev Y, Klenerman D. The scanned nanopipette: a new tool for high resolution bioimaging and controlled deposition of biomolecules. Physical Chemistry Chemical Physics : Pccp. 7: 2859-66. PMID 16189604 DOI: 10.1039/B506743J  0.774
2005 Zhang Y, Gorelik J, Sanchez D, Shevchuk A, Lab M, Vodyanoy I, Klenerman D, Edwards C, Korchev Y. Scanning ion conductance microscopy reveals how a functional renal epithelial monolayer maintains its integrity. Kidney International. 68: 1071-7. PMID 16105037 DOI: 10.1111/J.1523-1755.2005.00499.X  0.785
2005 Ali NN, Brito-Martins M, Gorelik J, Xu X, Korchev Y, Zhu H, Poole-Wilson PA, Fuller SJ, Harding SE. Pharmacological characterisation of embryonic stem cell-derived cardiomyocyte cultures Stem Cell Repair and Regeneration. 139-148. DOI: 10.1142/9781860949296_0010  0.691
2004 Darszon A, Wood CD, Beltrán C, Sánchez D, Rodríguez E, Gorelik J, Korchev YE, Nishigaki T. Measuring ion fluxes in sperm. Methods in Cell Biology. 74: 545-76. PMID 15575621 DOI: 10.1016/S0091-679X(04)74022-4  0.564
2004 Gorelik J, Shevchuk A, Swiet Md, Lab M, Korchev Y, Williamson C. Comparison of the arrhythmogenic effects of tauro‐ and glycoconjugates of cholic acid in an in vitro study of rat cardiomyocytes British Journal of Obstetrics and Gynaecology. 111: 867-870. PMID 15270939 DOI: 10.1111/J.1471-0528.2004.00166.X  0.782
2004 Gorelik J, Zhang Y, Shevchuk AI, Frolenkov GI, Sánchez D, Lab MJ, Vodyanoy I, Edwards CR, Klenerman D, Korchev YE. The use of scanning ion conductance microscopy to image A6 cells. Molecular and Cellular Endocrinology. 217: 101-8. PMID 15134807 DOI: 10.1016/J.Mce.2003.10.015  0.795
2003 Gorelik J, Vodyanoy I, Shevchuk AI, Diakonov IA, Lab MJ, Korchev YE. Esmolol is antiarrhythmic in doxorubicin-induced arrhythmia in cultured cardiomyocytes - determination by novel rapid cardiomyocyte assay. Febs Letters. 548: 74-8. PMID 12885410 DOI: 10.1016/S0014-5793(03)00743-9  0.797
2003 Gorelik J, Shevchuk AI, Frolenkov GI, Diakonov IA, Lab MJ, Kros CJ, Richardson GP, Vodyanoy I, Edwards CR, Klenerman D, Korchev YE. Dynamic assembly of surface structures in living cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 5819-22. PMID 12721367 DOI: 10.1073/Pnas.1030502100  0.79
2003 Rothery AM, Gorelik J, Bruckbauer A, Yu W, Korchev YE, Klenerman D. A novel light source for SICM-SNOM of living cells Journal of Microscopy. 209: 94-101. PMID 12588526 DOI: 10.1046/J.1365-2818.2003.01122.X  0.563
2003 Gorelik J, Shevchuk AI, Diakonov I, Swiet Md, Lab M, Korchev Y, Williamson C. Dexamethasone and ursodeoxycholic acid protect against the arrhythmogenic effect of taurocholate in an in vitro study of rat cardiomyocytes. British Journal of Obstetrics and Gynaecology. 110: 467-474. DOI: 10.1046/J.1471-0528.2003.02273.X  0.8
2002 Gorelik J, Gu Y, Spohr HA, Shevchuk AI, Lab MJ, Harding SE, Edwards CR, Whitaker M, Moss GW, Benton DC, Sánchez D, Darszon A, Vodyanoy I, Klenerman D, Korchev YE. Ion channels in small cells and subcellular structures can be studied with a smart patch-clamp system. Biophysical Journal. 83: 3296-303. PMID 12496097 DOI: 10.1016/S0006-3495(02)75330-7  0.801
2002 Gorelik J, Shevchuk A, Ramalho M, Elliott M, Lei C, Higgins CF, Lab MJ, Klenerman D, Krauzewicz N, Korchev Y. Scanning surface confocal microscopy for simultaneous topographical and fluorescence imaging: Application to single virus-like particle entry into a cell Proceedings of the National Academy of Sciences of the United States of America. 99: 16018-16023. PMID 12466501 DOI: 10.1073/Pnas.252458399  0.783
2002 Gorelik J, Harding SE, Shevchuk AI, Koralage D, Lab M, de Swiet M, Korchev Y, Williamson C. Taurocholate induces changes in rat cardiomyocyte contraction and calcium dynamics. Clinical Science (London, England : 1979). 103: 191-200. PMID 12149111 DOI: 10.1042/Cs1030191  0.802
2002 Gu Y, Gorelik J, Spohr HA, Shevchuk A, Lab MJ, Harding SE, Vodyanoy I, Klenerman D, Korchev YE. High-resolution scanning patch-clamp: new insights into cell function The Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 748-750. PMID 11923226 DOI: 10.1096/Fj.01-1024Fje  0.812
2001 Shevchuk AI, Gorelik J, Harding SE, Lab MJ, Klenerman D, Korchev YE. Simultaneous measurement of Ca2+ and cellular dynamics: Combined scanning ion conductance and optical microscopy to study contracting cardiac myocytes Biophysical Journal. 81: 1759-1764. PMID 11509385 DOI: 10.1016/S0006-3495(01)75826-2  0.824
2001 Williamson C, Gorelik J, Eaton BM, Lab M, Swiet Md, Korchev Y. The bile acid taurocholate impairs rat cardiomyocyte function: a proposed mechanism for intra-uterine fetal death in obstetric cholestasis. Clinical Science. 100: 363-369. DOI: 10.1042/Cs1000363  0.808
2000 Korchev YE, Raval M, Lab MJ, Gorelik J, Edwards CR, Rayment T, Klenerman D. Hybrid scanning ion conductance and scanning near-field optical microscopy for the study of living cells. Biophysical Journal. 78: 2675-9. PMID 10777763 DOI: 10.1016/S0006-3495(00)76811-1  0.717
2000 Korchev YE, Gorelik J, Lab MJ, Sviderskaya EV, Johnston CL, Coombes CR, Vodyanoy I, Edwards CR. Cell volume measurement using scanning ion conductance microscopy. Biophysical Journal. 78: 451-7. PMID 10620308 DOI: 10.1016/S0006-3495(00)76607-0  0.709
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