Timothy N. Perkins - Publications

Affiliations: 
University of Pittsburgh, Pittsburgh, PA, United States 

21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Kosanovich JL, Eichinger KM, Lipp MA, Gidwani SV, Brahmbhatt D, Yondola MA, Chi DH, Perkins TN, Empey KM. Lung ILC2s are activated in BALB/c mice born to immunized mothers despite complete protection against respiratory syncytial virus. Frontiers in Immunology. 15: 1374818. PMID 38827738 DOI: 10.3389/fimmu.2024.1374818  0.439
2023 Kosanovich JL, Eichinger KM, Lipp MA, Gidwani SV, Brahmbhatt D, Yondola MA, Perkins TN, Empey KM. Exacerbated lung inflammation following secondary RSV exposure is CD4+ T cell-dependent and is not mitigated in infant BALB/c mice born to PreF-vaccinated dams. Frontiers in Immunology. 14: 1206026. PMID 37646035 DOI: 10.3389/fimmu.2023.1206026  0.37
2023 Killian KN, Kosanovich JL, Lipp MA, Empey KM, Oury TD, Perkins TN. RAGE contributes to allergen driven severe neutrophilic airway inflammation NLRP3 inflammasome activation in mice. Frontiers in Immunology. 14: 1039997. PMID 36776857 DOI: 10.3389/fimmu.2023.1039997  0.714
2022 Eichinger KM, Kosanovich JL, Perkins TN, Oury TD, Petrovsky N, Marshall CP, Yondola MA, Empey KM. Prior respiratory syncytial virus infection reduces vaccine-mediated Th2-skewed immunity, but retains enhanced RSV F-specific CD8 T cell responses elicited by a Th1-skewing vaccine formulation. Frontiers in Immunology. 13: 1025341. PMID 36268035 DOI: 10.3389/fimmu.2022.1025341  0.508
2021 Perkins TN, Oury TD. The perplexing role of RAGE in pulmonary fibrosis: causality or casualty? Therapeutic Advances in Respiratory Disease. 15: 17534666211016071. PMID 34275342 DOI: 10.1177/17534666211016071  0.618
2020 Perkins TN, Donnell ML, Oury TD. The axis of the receptor for advanced glycation endproducts in asthma and allergic airway disease. Allergy. PMID 32976640 DOI: 10.1111/all.14600  0.718
2020 Eichinger KM, Kosanovich JL, Gidwani SV, Zomback A, Lipp MA, Perkins TN, Oury TD, Petrovsky N, Marshall CP, Yondola MA, Empey KM. Prefusion RSV F Immunization Elicits Th2-Mediated Lung Pathology in Mice When Formulated With a Th2 (but Not a Th1/Th2-Balanced) Adjuvant Despite Complete Viral Protection. Frontiers in Immunology. 11: 1673. PMID 32849580 DOI: 10.3389/Fimmu.2020.01673  0.636
2020 Kosanovich JL, Eichinger KM, Lipp MA, Yondola MA, Perkins TN, Empey KM. Formulation of the prefusion RSV F protein with a Th1/Th2-balanced adjuvant provides complete protection without Th2-skewed immunity in RSV-experienced young mice. Vaccine. 38: 6357-6362. PMID 32829976 DOI: 10.1016/J.Vaccine.2020.08.023  0.307
2019 Perkins TN, Oczypok EA, Dutz RE, Donnell ML, Myerburg MM, Oury TD. The Receptor for Advanced Glycation Endproducts is a Critical Mediator of Type 2 Cytokine Signaling in the Lungs. The Journal of Allergy and Clinical Immunology. PMID 30940519 DOI: 10.1016/J.Jaci.2019.03.019  0.662
2018 Perkins TN, Oczypok EA, Milutinovic PS, Dutz RE, Oury TD. RAGE-dependent VCAM-1 expression in the lung endothelium mediates IL-33 induced allergic airway inflammation. Allergy. PMID 29900561 DOI: 10.1111/All.13500  0.807
2018 Perkins TN, Peeters PM, Albrecht C, Schins RPF, Dentener MA, Mossman BT, Wouters EFM, Reynaert NL. Crystalline silica alters Sulfatase-1 expression in rat lungs which influences hyper-proliferative and fibrogenic effects in human lung epithelial cells. Toxicology and Applied Pharmacology. PMID 29673857 DOI: 10.1016/J.Taap.2018.04.011  0.423
2017 Oczypok EA, Perkins TN, Oury TD. All the "RAGE" in lung disease: The receptor for advanced glycation endproducts (RAGE) is a major mediator of pulmonary inflammatory responses. Paediatric Respiratory Reviews. PMID 28416135 DOI: 10.1016/J.Prrv.2017.03.012  0.775
2017 Oczypok EA, Perkins TN, Oury TD. Alveolar Epithelial Cell-derived Mediators: Potential Direct Regulators of Large Airway and Vascular Responses. American Journal of Respiratory Cell and Molecular Biology. PMID 28080134 DOI: 10.1165/Rcmb.2016-0151Ps  0.77
2017 Perkins T, Oczypok E, Dutz R, Oury T. RAGE-dependent VCAM-1 expression in the pulmonary endothelium mediates IL-33 induced asthma pathogenesis European Respiratory Journal. 50. DOI: 10.1183/1393003.Congress-2017.Pa4915  0.81
2016 Perkins TN, Dentener MA, Stassen FR, Rohde GG, Mossman BT, Wouters EF, Reynaert NL. Alteration of canonical and non-canonical WNT-signaling by crystalline silica in human lung epithelial cells. Toxicology and Applied Pharmacology. 301: 61-70. PMID 27095093 DOI: 10.1016/J.Taap.2016.04.003  0.461
2015 Perkins TN, Peeters PM, Shukla A, Arijs I, Dragon J, Wouters EF, Reynaert NL, Mossman BT. Indications for distinct pathogenic mechanisms of asbestos and silica through gene expression profiling of the response of lung epithelial cells. Human Molecular Genetics. 24: 1374-89. PMID 25351596 DOI: 10.1093/Hmg/Ddu551  0.387
2014 Peeters PM, Eurlings IM, Perkins TN, Wouters EF, Schins RP, Borm PJ, Drommer W, Reynaert NL, Albrecht C. Silica-induced NLRP3 inflammasome activation in vitro and in rat lungs. Particle and Fibre Toxicology. 11: 58. PMID 25406505 DOI: 10.1186/S12989-014-0058-0  0.384
2014 Sayan M, Shukla A, MacPherson MB, Macura SL, Hillegass JM, Perkins TN, Thompson JK, Beuschel SL, Miller JM, Mossman BT. Extracellular signal-regulated kinase 5 and cyclic AMP response element binding protein are novel pathways inhibited by vandetanib (ZD6474) and doxorubicin in mesotheliomas. American Journal of Respiratory Cell and Molecular Biology. 51: 595-603. PMID 24940987 DOI: 10.1165/Rcmb.2013-0373Tr  0.329
2013 Hillegass JM, Miller JM, MacPherson MB, Westbom CM, Sayan M, Thompson JK, Macura SL, Perkins TN, Beuschel SL, Alexeeva V, Pass HI, Steele C, Mossman BT, Shukla A. Asbestos and erionite prime and activate the NLRP3 inflammasome that stimulates autocrine cytokine release in human mesothelial cells. Particle and Fibre Toxicology. 10: 39. PMID 23937860 DOI: 10.1186/1743-8977-10-39  0.478
2013 Peeters PM, Perkins TN, Wouters EFM, Mossman BT, Reynaert NL. Silica induces NLRP3 inflammasome activation in human lung epithelial cells Particle and Fibre Toxicology. 10. PMID 23402370 DOI: 10.1186/1743-8977-10-3  0.513
2012 Perkins TN, Shukla A, Peeters PM, Steinbacher JL, Landry CC, Lathrop SA, Steele C, Reynaert NL, Wouters EF, Mossman BT. Differences in gene expression and cytokine production by crystalline vs. amorphous silica in human lung epithelial cells. Particle and Fibre Toxicology. 9: 6. PMID 22300531 DOI: 10.1186/1743-8977-9-6  0.412
Show low-probability matches.