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Kanakadurga Singer - Publications

Affiliations: 
Immunology University of Michigan Medical School Ann Arbor 
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50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Entrup GP, Unadkat A, Warheit-Niemi HI, Thomas B, Gurczynski SJ, Cui Y, Smith AM, Gallagher KA, Moore BB, Singer K. Obesity Inhibits Alveolar Macrophage Responses to Pseudomonas aeruginosa Pneumonia via Upregulation of Prostaglandin E2 in Male, but Not Female, Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 38905107 DOI: 10.4049/jimmunol.2400140  0.589
2023 Kim K, Varghese M, Sun H, Abrishami S, Bowers E, Bridges D, Meijer JL, Singer K, Gregg B. The influence of maternal high fat diet during lactation on offspring hematopoietic priming. Endocrinology. PMID 38048597 DOI: 10.1210/endocr/bqad182  0.35
2022 Varghese M, Clemente J, Lerner A, Abrishami S, Islam M, Subbaiah P, Singer K. Monocyte Trafficking and Polarization Contribute to Sex Differences in Meta-Inflammation. Frontiers in Endocrinology. 13: 826320. PMID 35422759 DOI: 10.3389/fendo.2022.826320  0.371
2021 Varghese M, Griffin C, Abrishami S, Eter L, Lanzetta N, Hak L, Clemente J, Agarwal D, Lerner A, Westerhoff M, Patel R, Bowers E, Islam M, Subbaiah P, Singer K. Sex hormones regulate meta-inflammation in diet-induced obesity in mice. The Journal of Biological Chemistry. 101229. PMID 34599964 DOI: 10.1016/j.jbc.2021.101229  0.46
2021 Bowers E, Singer K. Obesity-induced inflammation: The impact of the hematopoietic stem cell niche. Jci Insight. 6. PMID 33554957 DOI: 10.1172/jci.insight.145295  0.413
2020 Huizinga GP, Singer BH, Singer K. The Collision of Meta-Inflammation and SARS-CoV-2 Pandemic Infection. Endocrinology. PMID 32880654 DOI: 10.1210/Endocr/Bqaa154  0.573
2020 Ludzki AC, Krueger EM, Baldwin TC, Schleh MW, Porsche CE, Ryan BJ, Muir LA, Singer K, Lumeng CN, Horowitz JF. Acute Aerobic Exercise Remodels the Adipose Tissue Progenitor Cell Phenotype in Obese Adults. Frontiers in Physiology. 11: 903. PMID 32848853 DOI: 10.3389/Fphys.2020.00903  0.387
2020 Gállego-Suárez C, Bulan A, Hirschfeld E, Wachowiak P, Abrishami S, Griffin C, Sturza J, Tzau A, Hayes T, Woolford SJ, Lumeng CN, Lee JM, Singer K. Enhanced Myeloid Leukocytes in Obese Children and Adolescents at Risk for Metabolic Impairment. Frontiers in Endocrinology. 11: 327. PMID 32528415 DOI: 10.3389/Fendo.2020.00327  0.417
2020 McKernan K, Varghese M, Patel R, Singer K. Role of TLR4 in the induction of inflammatory changes in adipocytes and macrophages. Adipocyte. 9: 212-222. PMID 32403975 DOI: 10.1080/21623945.2020.1760674  0.433
2020 Zamarron BF, Porsche CE, Luan D, Lucas HR, Mergian TA, Martinez-Santibanez G, Cho KW, DelProposto JL, Geletka LM, Muir LA, Singer K, Lumeng CN. Weight Regain in Formerly Obese Mice Hastens Development of Hepatic Steatosis Due to Impaired Adipose Tissue Function. Obesity (Silver Spring, Md.). PMID 32281747 DOI: 10.1002/Oby.22788  0.437
2020 Davis FM, denDekker A, Kimball A, Joshi AD, El Azzouny M, Wolf SJ, Obi AT, Lipinski J, Gudjonsson JE, Xing X, Plazyo O, Audu C, Melvin WJ, Singer K, Henke PK, et al. Epigenetic Regulation of TLR4 in Diabetic Macrophages Modulates Immunometabolism and Wound Repair. Journal of Immunology (Baltimore, Md. : 1950). PMID 32205424 DOI: 10.4049/Jimmunol.1901263  0.542
2020 Varghese M, Griffin C, McKernan K, Eter L, Abrishami S, Singer K. Female adipose tissue has improved adaptability and metabolic health compared to males in aged obesity. Aging. 12: 1725-1746. PMID 31983693 DOI: 10.18632/aging.102709  0.434
2019 Puttabyatappa M, Ciarelli JN, Chatoff AG, Singer K, Padmanabhan V. Developmental programming: Adipose depot-specific changes and thermogenic adipocyte distribution in the female sheep. Molecular and Cellular Endocrinology. 503: 110691. PMID 31863810 DOI: 10.1016/J.Mce.2019.110691  0.362
2019 Chang E, Hafner H, Varghese M, Griffin C, Clemente J, Islam M, Carlson Z, Zhu A, Hak L, Abrishami S, Gregg B, Singer K. Programming effects of maternal and gestational obesity on offspring metabolism and metabolic inflammation. Scientific Reports. 9: 16027. PMID 31690792 DOI: 10.1038/S41598-019-52583-X  0.465
2019 Hafner H, Chang E, Carlson Z, Zhu A, Varghese M, Clemente J, Abrishami S, Bagchi DP, MacDougald OA, Singer K, Gregg B. Lactational High-Fat Diet Exposure Programs Metabolic Inflammation and Bone Marrow Adiposity in Male Offspring. Nutrients. 11. PMID 31234301 DOI: 10.3390/Nu11061393  0.431
2019 Griffin C, Hutch CR, Abrishami S, Stelmak D, Eter L, Li Z, Chang E, Agarwal D, Zamarron B, Varghese M, Subbaiah P, MacDougald OA, Sandoval DA, Singer K. Inflammatory responses to dietary and surgical weight loss in male and female mice. Biology of Sex Differences. 10: 16. PMID 30944030 DOI: 10.1186/S13293-019-0229-7  0.429
2019 Davis FM, Kimball A, denDekker A, Joshi AD, Boniakowski AE, Nysz D, Allen RM, Obi A, Singer K, Henke PK, Moore BB, Kunkel SL, Gallagher KA. Histone Methylation Directs Myeloid TLR4 Expression and Regulates Wound Healing following Cutaneous Tissue Injury. Journal of Immunology (Baltimore, Md. : 1950). PMID 30710046 DOI: 10.4049/Jimmunol.1801258  0.553
2019 Varghese M, Griffin C, McKernan K, Hayes T, Abrishami S, Singer K. SUN-105 Females Have Reduced Meta-Inflammation in Two States of Increased Adiposity, Obesity, and Aging Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Sun-105  0.46
2018 Varghese M, Griffin C, McKernan K, Eter L, Lanzetta N, Agarwal D, Abrishami S, Singer K. Sex differences in inflammatory responses to adipose tissue lipolysis in diet-induced obesity. Endocrinology. PMID 30544158 DOI: 10.1210/En.2018-00797  0.502
2018 Stojanovska J, Lumeng CN, Griffin C, Hernando D, Hoffmann U, Haft JW, Kim KM, Burant CF, Singer K, Tsodikov A, Long BD, Romano MA, Tang PC, Yang B, Chenevert TL. Water-fat magnetic resonance imaging quantifies relative proportions of brown and white adipose tissues: experiments. Journal of Medical Imaging (Bellingham, Wash.). 5: 024007. PMID 30137870 DOI: 10.1117/1.Jmi.5.2.024007  0.35
2018 Chang E, Varghese M, Singer K. Gender and Sex Differences in Adipose Tissue. Current Diabetes Reports. 18: 69. PMID 30058013 DOI: 10.1007/S11892-018-1031-3  0.507
2018 Griffin C, Eter L, Lanzetta N, Abrishami S, Varghese M, McKernan K, Muir L, Lane J, Lumeng CN, Singer K. TLR4, TRIF, and MyD88 are essential for myelopoiesis and CD11c+ adipose tissue macrophage production in obese mice. The Journal of Biological Chemistry. PMID 29636416 DOI: 10.1074/Jbc.Ra117.001526  0.484
2018 Muir LA, Kiridena S, Griffin C, DelProposto JB, Geletka L, Martinez-Santibañez G, Zamarron BF, Lucas H, Singer K, O' Rourke RW, Lumeng CN. Rapid adipose tissue expansion triggers unique proliferation and lipid accumulation profiles in adipose tissue macrophages. Journal of Leukocyte Biology. PMID 29493813 DOI: 10.1002/Jlb.3Hi1017-422R  0.47
2018 Peterson LS, Gállego Suárez C, Segaloff HE, Griffin C, Martin ET, Odetola FO, Singer K. Outcomes and Resource Use Among Overweight and Obese Children With Sepsis in the Pediatric Intensive Care Unit. Journal of Intensive Care Medicine. 885066618760541. PMID 29471722 DOI: 10.1177/0885066618760541  0.372
2018 Griffin CA, Abrishami S, Varghese M, Singer K. Androgens Activate Myeloid Cells during High-Fat Diet Exposure Promoting Sex Differences in Metabolic Disease Diabetes. 67. DOI: 10.2337/Db18-282-Or  0.507
2018 Varghese M, Abrishami S, Singer K. Adipocyte Lipolysis Triggers CD11c-ATM Inflammation in Lean Females and Obese Males and Females Diabetes. 67. DOI: 10.2337/Db18-2021-P  0.499
2018 HUTCH C, STELMAK D, SINGER K, SANDOVAL DA. Diet-Dependent Sex Differences in the Response to Bariatric Surgery Diabetes. 67: 2013-P. DOI: 10.2337/Db18-2013-P  0.339
2017 Varghese M, Griffin C, Singer K. The Role of Sex and Sex Hormones in Regulating Obesity-Induced Inflammation. Advances in Experimental Medicine and Biology. 1043: 65-86. PMID 29224091 DOI: 10.1007/978-3-319-70178-3_5  0.517
2017 Molloy CT, Adkins LJ, Griffin C, Singer K, Weinberg JB. Mouse adenovirus type 1 infection of adipose tissue. Virus Research. 244: 90-98. PMID 29141203 DOI: 10.1016/J.Virusres.2017.11.014  0.469
2017 Gállego Suárez C, Singer BH, Gebremariam A, Lee JM, Singer K. The relationship between adiposity and bone density in U.S. children and adolescents. Plos One. 12: e0181587. PMID 28723934 DOI: 10.1371/Journal.Pone.0181587  0.303
2017 Zamarron BF, Mergian TA, Cho KW, Martinez-Santibanez G, Luan D, Singer K, DelProposto JL, Geletka LM, Muir LA, Lumeng CN. Macrophage Proliferation Sustains Adipose Tissue Inflammation in Formerly Obese Mice. Diabetes. 66: 392-406. PMID 28108608 DOI: 10.2337/Db16-0500  0.515
2017 Singer K, Lumeng CN. The initiation of metabolic inflammation in childhood obesity. The Journal of Clinical Investigation. 127: 65-73. PMID 28045405 DOI: 10.1172/Jci88882  0.413
2017 Maley N, Gebremariam A, Odetola F, Singer K. Influence of Obesity Diagnosis With Organ Dysfunction, Mortality, and Resource Use Among Children Hospitalized With Infection in the United States. Journal of Intensive Care Medicine. 32: 339-345. PMID 26880005 DOI: 10.1177/0885066616631325  0.429
2016 Cho KW, Zamarron BF, Muir LA, Singer K, Porsche CE, DelProposto JB, Geletka L, Meyer KA, O'Rourke RW, Lumeng CN. Adipose Tissue Dendritic Cells Are Independent Contributors to Obesity-Induced Inflammation and Insulin Resistance. Journal of Immunology (Baltimore, Md. : 1950). PMID 27683748 DOI: 10.4049/Jimmunol.1600820  0.44
2016 Scheller EL, Khoury B, Moller KL, Wee NK, Khandaker S, Kozloff KM, Abrishami SH, Zamarron BF, Singer K. Changes in Skeletal Integrity and Marrow Adiposity during High-Fat Diet and after Weight Loss. Frontiers in Endocrinology. 7: 102. PMID 27512386 DOI: 10.3389/Fendo.2016.00102  0.406
2016 Griffin C, Lanzetta N, Eter L, Singer K. Sexually Dimorphic Myeloid Inflammatory and Metabolic Responses to Diet-Induced Obesity. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00136.2016. PMID 27252473 DOI: 10.1152/Ajpregu.00136.2016  0.465
2016 Singer BH, Newstead MW, Zeng X, Cooke CL, Thompson RC, Singer K, Ghantasala R, Parent JM, Murphy GG, Iwashyna TJ, Standiford TJ. Cecal Ligation and Puncture Results in Long-Term Central Nervous System Myeloid Inflammation. Plos One. 11: e0149136. PMID 26862765 DOI: 10.1371/Journal.Pone.0149136  0.3
2015 Morris DL, Oatmen KE, Mergian TA, Cho KW, DelProposto JL, Singer K, Evans-Molina C, O'Rourke RW, Lumeng CN. CD40 promotes MHC class II expression on adipose tissue macrophages and regulates adipose tissue CD4+ T cells with obesity. Journal of Leukocyte Biology. PMID 26658005 DOI: 10.1189/Jlb.3A0115-009R  0.407
2015 Veiga-Lopez A, Moeller J, Sreedharan R, Singer K, Lumeng CN, Ye W, Pease A, Padmanabhan V. Developmental programming: interaction between prenatal BPA exposure and postnatal adiposity on metabolic variables in female sheep. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00425.2015. PMID 26646100 DOI: 10.1152/Ajpendo.00425.2015  0.38
2015 Martinez-Santibanez G, Singer K, Cho KW, DelProposto JL, Mergian T, Lumeng CN. Obesity-induced remodeling of the adipose tissue elastin network is independent of the metalloelastase MMP-12. Adipocyte. 4: 264-72. PMID 26451282 DOI: 10.1080/21623945.2015.1027848  0.387
2015 Singer K, Maley N, Mergian T, DelProposto J, Cho KW, Zamarron BF, Martinez-Santibanez G, Geletka L, Muir L, Wachowiak P, Demirjian C, Lumeng CN. Differences in Hematopoietic Stem Cells Contribute to Sexually Dimorphic Inflammatory Responses to High Fat Diet-induced Obesity. The Journal of Biological Chemistry. 290: 13250-62. PMID 25869128 DOI: 10.1074/Jbc.M114.634568  0.502
2014 Cho KW, Morris DL, DelProposto JL, Geletka L, Zamarron B, Martinez-Santibanez G, Meyer KA, Singer K, O'Rourke RW, Lumeng CN. An MHC II-dependent activation loop between adipose tissue macrophages and CD4+ T cells controls obesity-induced inflammation. Cell Reports. 9: 605-17. PMID 25310975 DOI: 10.1016/J.Celrep.2014.09.004  0.46
2014 Singer K, DelProposto J, Morris DL, Zamarron B, Mergian T, Maley N, Cho KW, Geletka L, Subbaiah P, Muir L, Martinez-Santibanez G, Lumeng CN. Diet-induced obesity promotes myelopoiesis in hematopoietic stem cells. Molecular Metabolism. 3: 664-75. PMID 25161889 DOI: 10.1016/J.Molmet.2014.06.005  0.522
2014 Singer K, Eng DS, Lumeng CN, Gebremariam A, M Lee J. The relationship between body fat mass percentiles and inflammation in children. Obesity (Silver Spring, Md.). 22: 1332-6. PMID 24464763 DOI: 10.1002/Oby.20710  0.415
2013 Morris DL, Cho KW, Delproposto JL, Oatmen KE, Geletka LM, Martinez-Santibanez G, Singer K, Lumeng CN. Adipose tissue macrophages function as antigen-presenting cells and regulate adipose tissue CD4+ T cells in mice. Diabetes. 62: 2762-72. PMID 23493569 DOI: 10.2337/Db12-1404  0.45
2013 Singer K, Morris DL, Oatmen KE, Wang T, DelProposto J, Mergian T, Cho KW, Lumeng CN. Neuropeptide Y is produced by adipose tissue macrophages and regulates obesity-induced inflammation. Plos One. 8: e57929. PMID 23472120 DOI: 10.1371/Journal.Pone.0057929  0.507
2013 Singer K, Morris DL, Oatmen KE, Wang T, DelProposto J, Mergian T, Cho KW, Lumeng CN. Correction: Neuropeptide Y Is Produced by Adipose Tissue Macrophages and Regulates Obesity-Induced Inflammation Plos One. 8. DOI: 10.1371/annotation/c2432ace-1dd7-4b02-8980-e4e6c085beba  0.433
2011 Morris DL, Singer K, Lumeng CN. Adipose tissue macrophages: phenotypic plasticity and diversity in lean and obese states. Current Opinion in Clinical Nutrition and Metabolic Care. 14: 341-6. PMID 21587064 DOI: 10.1097/Mco.0B013E328347970B  0.505
2009 Westcott DJ, Delproposto JB, Geletka LM, Wang T, Singer K, Saltiel AR, Lumeng CN. MGL1 promotes adipose tissue inflammation and insulin resistance by regulating 7/4hi monocytes in obesity. The Journal of Experimental Medicine. 206: 3143-56. PMID 19995956 DOI: 10.1084/Jem.20091333  0.524
2005 Kasa-Vubu JZ, Lee CC, Rosenthal A, Singer K, Halter JB. Cardiovascular fitness and exercise as determinants of insulin resistance in postpubertal adolescent females. The Journal of Clinical Endocrinology and Metabolism. 90: 849-54. PMID 15572432 DOI: 10.1210/Jc.2004-0455  0.321
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