☰

Marc Whitlow - Publications

Affiliations: 
Chemistry Boston University School of Medicine, Boston, MA 
Tree Info Similar researchers PubMed Report error

0/23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
Low-probability matches (unlikely to be authored by this person)
2018 Islam I, Yuan S, West CW, Adler M, Bothe U, Bryant J, Chang Z, Chu K, Emayan K, Gualtieri G, Ho E, Light D, Mallari C, Morser J, Phillips G, ... ... Whitlow M, et al. Discovery of selective urokinase plasminogen activator (uPA) inhibitors as a potential treatment for multiple sclerosis. Bioorganic & Medicinal Chemistry Letters. PMID 30201291 DOI: 10.1016/j.bmcl.2018.09.001  0.01
2016 Oshima S, Karrer EE, Paidhungat MM, Neighbors M, Chapin SJ, Fan RA, Reed MA, Wu K, Wong C, Chen Y, Whitlow M, Anderson FA, Bam RA, Zhang Q, Larsen BR, et al. ASP2408 and ASP2409, novel CTLA4-Ig variants with CD86-selective ligand binding activity and improved immunosuppressive potency, created by directed evolution. Protein Engineering, Design & Selection : Peds. PMID 26968452 DOI: 10.1093/protein/gzw002  0.01
2009 West CW, Adler M, Arnaiz D, Chen D, Chu K, Gualtieri G, Ho E, Huwe C, Light D, Phillips G, Pulk R, Sukovich D, Whitlow M, Yuan S, Bryant J. Identification of orally bioavailable, non-amidine inhibitors of Urokinase Plasminogen Activator (uPA). Bioorganic & Medicinal Chemistry Letters. 19: 5712-5. PMID 19703768 DOI: 10.1016/j.bmcl.2009.08.008  0.01
2009 Feldman RI, Mintzer B, Zhu D, Wu JM, Biroc SL, Yuan S, Emayan K, Chang Z, Chen D, Arnaiz DO, Bryant J, Ge XS, Whitlow M, Adler M, Polokoff MA, et al. Potent triazolothione inhibitor of heat-shock protein-90. Chemical Biology & Drug Design. 74: 43-50. PMID 19519743 DOI: 10.1111/j.1747-0285.2009.00833.x  0.01
2009 Wu C, Kim PY, Manuel R, Seto M, Whitlow M, Nagashima M, Morser J, Gils A, Declerck P, Nesheim ME. The roles of selected arginine and lysine residues of TAFI (Pro-CPU) in its activation to TAFIa by the thrombin-thrombomodulin complex. The Journal of Biological Chemistry. 284: 7059-67. PMID 19074424 DOI: 10.1074/Jbc.M804745200  0.01
2008 Kirkland TA, Adler M, Bauman JG, Chen M, Haeggström JZ, King B, Kochanny MJ, Liang AM, Mendoza L, Phillips GB, Thunnissen M, Trinh L, Whitlow M, Ye B, Ye H, et al. Synthesis of glutamic acid analogs as potent inhibitors of leukotriene A4 hydrolase. Bioorganic & Medicinal Chemistry. 16: 4963-83. PMID 18394906 DOI: 10.1016/j.bmc.2008.03.042  0.01
2008 Adler M, Buckman B, Bryant J, Chang Z, Chu K, Emayan K, Hrvatin P, Islam I, Morser J, Sukovich D, West C, Yuan S, Whitlow M. Structures of potent selective peptide mimetics bound to carboxypeptidase B Acta Crystallographica Section D: Biological Crystallography. 64: 149-157. PMID 18219114 DOI: 10.1107/S0907444907057228  0.01
2007 Islam I, Brown G, Bryant J, Hrvatin P, Kochanny MJ, Phillips GB, Yuan S, Adler M, Whitlow M, Lentz D, Polokoff MA, Wu J, Shen J, Walters J, Ho E, et al. Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 2: optimization of BX-517. Bioorganic & Medicinal Chemistry Letters. 17: 3819-25. PMID 17544272 DOI: 10.1016/j.bmcl.2007.05.060  0.01
2007 Ye B, Arnaiz DO, Chou YL, Griedel BD, Karanjawala R, Lee W, Morrissey MM, Sacchi KL, Sakata ST, Shaw KJ, Wu SC, Zhao Z, Adler M, Cheeseman S, Dole WP, ... ... Whitlow M, et al. Thiophene-anthranilamides as highly potent and orally available factor Xa inhibitors. Journal of Medicinal Chemistry. 50: 2967-80. PMID 17536795 DOI: 10.1021/jm070125f  0.01
2007 Islam I, Bryant J, Chou YL, Kochanny MJ, Lee W, Phillips GB, Yu H, Adler M, Whitlow M, Ho E, Lentz D, Polokoff MA, Subramanyam B, Wu JM, Zhu D, et al. Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 1: design, synthesis and biological activity. Bioorganic & Medicinal Chemistry Letters. 17: 3814-8. PMID 17531483 DOI: 10.1016/j.bmcl.2007.04.071  0.01
2007 Wei RG, Adler M, Davey D, Ho E, Mohan R, Polokoff M, Tseng JL, Whitlow M, Xu W, Yuan S, Phillips G. 1-(1,3-Benzodioxol-5-ylmethyl)-3-[4-(1H-imidazol-1-yl)phenoxy]-piperidine analogs as potent and selective inhibitors of nitric oxide formation Bioorganic and Medicinal Chemistry Letters. 17: 2499-2504. PMID 17368901 DOI: 10.1016/j.bmcl.2007.02.053  0.01
2007 Whitlow M, Adler M, Davey D, Huang Q, Koovakkat S, Parkinson JF, Pham E, Polokoff M, Xu W, Yuan S, Phillips G. The rational design of inhibitors of nitric oxide formation by inducible nitric oxide synthase. Bioorganic & Medicinal Chemistry Letters. 17: 2505-8. PMID 17336523 DOI: 10.1016/j.bmcl.2007.02.018  0.01
2007 Davey DD, Adler M, Arnaiz D, Eagen K, Erickson S, Guilford W, Kenrick M, Morrissey MM, Ohlmeyer M, Pan G, Paradkar VM, Parkinson J, Polokoff M, Saionz K, Santos C, ... ... Whitlow M, et al. Design, synthesis, and activity of 2-imidazol-1-ylpyrimidine derived inducible nitric oxide synthase dimerization inhibitors. Journal of Medicinal Chemistry. 50: 1146-57. PMID 17315988 DOI: 10.1021/jm061319i  0.01
2007 Kochanny MJ, Adler M, Ewing J, Griedel BD, Ho E, Karanjawala R, Lee W, Lentz D, Liang AM, Morrissey MM, Phillips GB, Post J, Sacchi KL, Sakata ST, Subramanyam B, ... ... Whitlow M, et al. Substituted thiophene-anthranilamides as potent inhibitors of human factor Xa. Bioorganic & Medicinal Chemistry. 15: 2127-46. PMID 17227710 DOI: 10.1016/j.bmc.2006.12.019  0.01
2007 Islam I, Bryant J, May K, Mohan R, Yuan S, Kent L, Morser J, Zhao L, Vergona R, White K, Adler M, Whitlow M, Buckman BO. 3-Mercaptopropionic acids as efficacious inhibitors of activated thrombin activatable fibrinolysis inhibitor (TAFIa). Bioorganic & Medicinal Chemistry Letters. 17: 1349-54. PMID 17189688 DOI: 10.1016/j.bmcl.2006.11.078  0.01
2006 Xuan JA, Schneider D, Toy P, Lin R, Newton A, Zhu Y, Finster S, Vogel D, Mintzer B, Dinter H, Light D, Parry R, Polokoff M, Whitlow M, Wu Q, et al. Antibodies neutralizing hepsin protease activity do not impact cell growth but inhibit invasion of prostate and ovarian tumor cells in culture. Cancer Research. 66: 3611-9. PMID 16585186 DOI: 10.1158/0008-5472.CAN-05-2983  0.01
2005 Kohrt JT, Filipski KJ, Cody WL, Cai C, Dudley DA, Van Huis CA, Willardsen JA, Rapundalo ST, Saiya-Cork K, Leadley RJ, Narasimhan L, Zhang E, Whitlow M, Adler M, McLean K, et al. The discovery of fluoropyridine-based inhibitors of the Factor VIIa/TF complex. Bioorganic & Medicinal Chemistry Letters. 15: 4752-6. PMID 16125385 DOI: 10.1016/j.bmcl.2005.07.059  0.01
2005 Adler M, Bryant J, Buckman B, Islam I, Larsen B, Finster S, Kent L, May K, Mohan R, Yuan S, Whitlow M. Crystal structures of potent thiol-based inhibitors bound to carboxypeptidase B Biochemistry. 44: 9339-9347. PMID 15982000 DOI: 10.1021/bi0501941  0.01
2005 Feldman RI, Wu JM, Polokoff MA, Kochanny MJ, Dinter H, Zhu D, Biroc SL, Alicke B, Bryant J, Yuan S, Buckman BO, Lentz D, Ferrer M, Whitlow M, Adler M, et al. Novel small molecule inhibitors of 3-phosphoinositide-dependent kinase-1. The Journal of Biological Chemistry. 280: 19867-74. PMID 15772071 DOI: 10.1074/jbc.M501367200  0.01
2004 Seto M, Whitlow M, McCarrick MA, Srinivasan S, Zhu Y, Pagila R, Mintzer R, Light D, Johns A, Meurer-Ogden JA. A model of the acid sphingomyelinase phosphoesterase domain based on its remote structural homolog purple acid phosphatase. Protein Science : a Publication of the Protein Society. 13: 3172-86. PMID 15557261 DOI: 10.1110/ps.04966204  0.01
2002 Adler M, Kochanny MJ, Ye B, Rumennik G, Light DR, Biancalana S, Whitlow M. Crystal structures of two potent nonamidine inhibitors bound to factor Xa Biochemistry. 41: 15514-15523. PMID 12501180 DOI: 10.1021/bi0264061  0.01
2002 Phillips G, Guilford WJ, Buckman BO, Davey DD, Eagen KA, Koovakkat S, Liang A, McCarrick M, Mohan R, Ng HP, Pinkerton M, Subramanyam B, Ho E, Trinh L, Whitlow M, et al. Design, synthesis, and activity of a novel series of factor Xa inhibitors: optimization of arylamidine groups. Journal of Medicinal Chemistry. 45: 2484-93. PMID 12036356 DOI: 10.1021/jm0200660  0.01
2002 Blasko E, Glaser CB, Devlin JJ, Xia W, Feldman RI, Polokoff MA, Phillips GB, Whitlow M, Auld DS, McMillan K, Ghosh S, Stuehr DJ, Parkinson JF. Mechanistic studies with potent and selective inducible nitric-oxide synthase dimerization inhibitors. The Journal of Biological Chemistry. 277: 295-302. PMID 11689556 DOI: 10.1074/Jbc.M105691200  0.01
Hide low-probability matches.