Year |
Citation |
Score |
2024 |
Monsen RC, Sabo TM, Gray R, Hopkins JB, Chaires JB. Early Events in G-quadruplex Folding Captured by Time-Resolved Small-Angle X-Ray Scattering. Biorxiv : the Preprint Server For Biology. PMID 39282441 DOI: 10.1101/2024.09.05.611539 |
0.78 |
|
2024 |
Michael Sabo T, Trent JO, Chaires JB, Monsen RC. Strategy for modeling higher-order G-quadruplex structures recalcitrant to NMR determination. Methods (San Diego, Calif.). PMID 39032720 DOI: 10.1016/j.ymeth.2024.07.004 |
0.807 |
|
2024 |
Chakraborty G, Balinin K, Villar-Guerra RD, Emondts M, Portale G, Loznik M, Niels Klement WJ, Zheng L, Weil T, Chaires JB, Herrmann A. Supramolecular DNA-based catalysis in organic solvents. Iscience. 27: 109689. PMID 38706840 DOI: 10.1016/j.isci.2024.109689 |
0.367 |
|
2023 |
Monsen RC, Chua EYD, Hopkins JB, Chaires JB, Trent JO. Structure of a 28.5 kDa duplex-embedded G-quadruplex system resolved to 7.4 Å resolution with cryo-EM. Nucleic Acids Research. PMID 36715343 DOI: 10.1093/nar/gkad014 |
0.805 |
|
2022 |
Monsen RC, Trent JO, Chaires JB. G-quadruplex DNA: A Longer Story. Accounts of Chemical Research. PMID 36282946 DOI: 10.1021/acs.accounts.2c00519 |
0.808 |
|
2022 |
Monsen RC, Maguire JM, DeLeeuw LW, Chaires JB, Trent JO. Drug discovery of small molecules targeting the higher-order hTERT promoter G-quadruplex. Plos One. 17: e0270165. PMID 35709230 DOI: 10.1371/journal.pone.0270165 |
0.792 |
|
2022 |
Monsen RC, DeLeeuw LW, Dean WL, Gray RD, Chakravarthy S, Hopkins JB, Chaires JB, Trent JO. Long promoter sequences form higher-order G-quadruplexes: an integrative structural biology study of c-Myc, k-Ras and c-Kit promoter sequences. Nucleic Acids Research. 50: 4127-4147. PMID 35325198 DOI: 10.1093/nar/gkac182 |
0.781 |
|
2021 |
DeLeeuw LW, Monsen RC, Petrauskas V, Gray RD, Baranauskiene L, Matulis D, Trent JO, Chaires JB. POT1 stability and binding measured by fluorescence thermal shift assays. Plos One. 16: e0245675. PMID 33784306 DOI: 10.1371/journal.pone.0245675 |
0.773 |
|
2021 |
Monsen RC, Chakravarthy S, Dean WL, Chaires JB, Trent JO. The solution structures of higher-order human telomere G-quadruplex multimers. Nucleic Acids Research. PMID 33469644 DOI: 10.1093/nar/gkaa1285 |
0.799 |
|
2020 |
Chaires JB, Gray RD, Dean WL, Monsen R, DeLeeuw LW, Stribinskis V, Trent JO. Human POT1 unfolds G-quadruplexes by conformational selection. Nucleic Acids Research. PMID 32232414 DOI: 10.1093/Nar/Gkaa202 |
0.804 |
|
2020 |
Monsen RC, DeLeeuw L, Dean WL, Gray RD, Sabo TM, Chakravarthy S, Chaires JB, Trent JO. The hTERT core promoter forms three parallel G-quadruplexes. Nucleic Acids Research. PMID 32083666 DOI: 10.1093/Nar/Gkaa107 |
0.793 |
|
2019 |
Mestre-Fos S, Penev PI, Richards JC, Dean WL, Gray RD, Chaires JB, Williams LD. Profusion of G-quadruplexes on both subunits of metazoan ribosomes. Plos One. 14: e0226177. PMID 31834895 DOI: 10.1371/Journal.Pone.0226177 |
0.39 |
|
2019 |
Dean WL, Gray RD, DeLeeuw L, Monsen RC, Chaires JB. Putting a New Spin of G-Quadruplex Structure and Binding by Analytical Ultracentrifugation. Methods in Molecular Biology (Clifton, N.J.). 2035: 87-103. PMID 31444745 DOI: 10.1007/978-1-4939-9666-7_5 |
0.785 |
|
2019 |
Gray RD, Trent JO, Arumugam S, Chaires JB. Folding Landscape of a Parallel G-Quadruplex. The Journal of Physical Chemistry Letters. 1146-1151. PMID 30802054 DOI: 10.1021/Acs.Jpclett.9B00227 |
0.347 |
|
2018 |
Zahin M, Dean WL, Ghim SJ, Joh J, Gray RD, Khanal S, Bossart GD, Mignucci-Giannoni AA, Rouchka EC, Jenson AB, Trent JO, Chaires JB, Chariker JH. Identification of G-quadruplex forming sequences in three manatee papillomaviruses. Plos One. 13: e0195625. PMID 29630682 DOI: 10.1371/Journal.Pone.0195625 |
0.415 |
|
2018 |
del Villar-Guerra R, Trent JO, Chaires JB. Back Cover: G-Quadruplex Secondary Structure Obtained from Circular Dichroism Spectroscopy (Angew. Chem. Int. Ed. 24/2018) Angewandte Chemie International Edition. 57: 7256-7256. DOI: 10.1002/anie.201712043 |
0.409 |
|
2018 |
del Villar-Guerra R, Trent JO, Chaires JB. Rücktitelbild: G-Quadruplex Secondary Structure Obtained from Circular Dichroism Spectroscopy (Angew. Chem. 24/2018) Angewandte Chemie. 130: 7376-7376. DOI: 10.1002/ange.201712043 |
0.425 |
|
2017 |
Rigo R, Dean WL, Gray RD, Chaires JB, Sissi C. Conformational profiling of a G-rich sequence within the c-KIT promoter. Nucleic Acids Research. PMID 29069417 DOI: 10.1093/Nar/Gkx983 |
0.426 |
|
2016 |
Bončina M, Vesnaver G, Chaires JB, Lah J. Unraveling the Thermodynamics of the Folding and Interconversion of Human Telomere G-Quadruplexes. Angewandte Chemie (International Ed. in English). PMID 27484724 DOI: 10.1002/anie.201605350 |
0.365 |
|
2015 |
Chaires JB, Dean WL, Le HT, Trent JO. Hydrodynamic Models of G-Quadruplex Structures. Methods in Enzymology. 562: 287-304. PMID 26412657 DOI: 10.1016/bs.mie.2015.04.011 |
0.419 |
|
2015 |
Chaires JB, Levene SD. Preface. Biopolymers. 103: 469. PMID 26015222 DOI: 10.1002/bip.22686 |
0.587 |
|
2015 |
Chaires JB, Levene SD. Preface. Biopolymers. 103: 417. PMID 26010347 DOI: 10.1002/bip.22661 |
0.587 |
|
2015 |
Miller DM, Sokolova A, Rezzoug F, Thomas S, Chaires J, Dean W, Trent J. Abstract PR02: Specific inhibition of hTERT expression in melanoma by targeting common promoter mutations which cause quadruplex DNA instability Cancer Research. 75. DOI: 10.1158/1538-7445.Mel2014-Pr02 |
0.303 |
|
2015 |
Chaires JB, Dean WL, Le HT, Trent JO. Hydrodynamic Models of G-Quadruplex Structures Methods in Enzymology. DOI: 10.1016/bs.mie.2015.04.011 |
0.403 |
|
2014 |
Le HT, Dean WL, Buscaglia R, Chaires JB, Trent JO. An investigation of G-quadruplex structural polymorphism in the human telomere using a combined approach of hydrodynamic bead modeling and molecular dynamics simulation. The Journal of Physical Chemistry. B. 118: 5390-405. PMID 24779348 DOI: 10.1021/jp502213y |
0.454 |
|
2014 |
Gray RD, Trent JO, Chaires JB. Folding and unfolding pathways of the human telomeric G-quadruplex. Journal of Molecular Biology. 426: 1629-50. PMID 24487181 DOI: 10.1016/J.Jmb.2014.01.009 |
0.338 |
|
2013 |
Buscaglia R, Miller MC, Dean WL, Gray RD, Lane AN, Trent JO, Chaires JB. Polyethylene glycol binding alters human telomere G-quadruplex structure by conformational selection. Nucleic Acids Research. 41: 7934-46. PMID 23804761 DOI: 10.1093/Nar/Gkt440 |
0.356 |
|
2013 |
Buscaglia R, Gray RD, Chaires JB. Thermodynamic characterization of human telomere quadruplex unfolding. Biopolymers. 99: 1006-18. PMID 23536479 DOI: 10.1002/Bip.22247 |
0.304 |
|
2013 |
Le HT, Buscaglia R, Dean WL, Chaires JB, Trent JO. Calculation of hydrodynamic properties for G-quadruplex nucleic acid structures from in silico bead models. Topics in Current Chemistry. 330: 179-210. PMID 22886555 DOI: 10.1007/128_2012_351 |
0.472 |
|
2013 |
Le HT, Buscaglia R, Dean WL, Chaires JB, Trent JO. Calculation of hydrodynamic properties for G-quadruplex nucleic acid structures from in silico bead models Topics in Current Chemistry. 330: 179-210. DOI: 10.1007/128-2012-351 |
0.323 |
|
2012 |
Le HT, Miller MC, Buscaglia R, Dean WL, Holt PA, Chaires JB, Trent JO. Not all G-quadruplexes are created equally: An investigation of the structural polymorphism of the c-Myc G-quadruplex-forming sequence and its interaction with the porphyrin TMPyP4 Organic and Biomolecular Chemistry. 10: 9393-9404. PMID 23108607 DOI: 10.1039/c2ob26504d |
0.453 |
|
2012 |
Gray RD, Chaires JB. Isothermal folding of G-quadruplexes. Methods (San Diego, Calif.). 57: 47-55. PMID 22525787 DOI: 10.1016/J.Ymeth.2012.04.006 |
0.411 |
|
2012 |
Buscaglia R, Jameson DM, Chaires JB. G-quadruplex structure and stability illuminated by 2-aminopurine phasor plots. Nucleic Acids Research. 40: 4203-15. PMID 22241767 DOI: 10.1093/Nar/Gkr1286 |
0.339 |
|
2012 |
Buscaglia R, Jameson DM, Chaires JB. Phasor Diagram Analysis of Telomeric G-Quadruplex Stability and Heterogeneity Biophysical Journal. 102: 209a. DOI: 10.1016/J.Bpj.2011.11.1140 |
0.404 |
|
2011 |
Petraccone L, Spink C, Trent JO, Garbett NC, Mekmaysy CS, Giancola C, Chaires JB. Structure and stability of higher-order human telomeric quadruplexes Journal of the American Chemical Society. 133: 20951-20961. PMID 22082001 DOI: 10.1021/ja209192a |
0.394 |
|
2011 |
Holt PA, Buscaglia R, Trent JO, Chaires JB. A Discovery Funnel for Nucleic Acid Binding Drug Candidates. Drug Development Research. 72: 178-186. PMID 21566705 DOI: 10.1002/ddr.20414 |
0.307 |
|
2010 |
Miller MC, Buscaglia R, Chaires JB, Lane AN, Trent JO. Hydration is a major determinant of the G-quadruplex stability and conformation of the human telomere 3′ sequence of d(AG 3(TTAG3)3) Journal of the American Chemical Society. 132: 17105-17107. PMID 21087016 DOI: 10.1021/ja105259m |
0.348 |
|
2010 |
Petraccone L, Garbett NC, Chaires JB, Trent JO. An integrated molecular dynamics (MD) and experimental study of higher order human telomeric quadruplexes Biopolymers. 93: 533-548. PMID 20095044 DOI: 10.1002/bip.21392 |
0.38 |
|
2010 |
Gray RD, Petraccone L, Trent JO, Chaires JB. Characterization of a K+-induced conformational switch in a human telomeric DNA oligonucleotide using 2-aminopurine fluorescence. Biochemistry. 49: 179-94. PMID 19961180 DOI: 10.1021/Bi901357R |
0.328 |
|
2010 |
Chaires JB. Human telomeric G-quadruplex: Thermodynamic and kinetic studies of telomeric quadruplex stability Febs Journal. 277: 1098-1106. PMID 19951355 DOI: 10.1111/j.1742-4658.2009.07462.x |
0.369 |
|
2009 |
Gray RD, Li J, Chaires JB. Energetics and kinetics of a conformational switch in G-quadruplex DNA Journal of Physical Chemistry B. 113: 2676-2683. DOI: 10.1021/jp809578f |
0.382 |
|
2008 |
Lane AN, Chaires JB, Gray RD, Trent JO. Stability and kinetics of G-quadruplex structures. Nucleic Acids Research. 36: 5482-515. PMID 18718931 DOI: 10.1093/Nar/Gkn517 |
0.369 |
|
2008 |
Gray RD, Chaires JB. Kinetics and mechanism of K+- and Na+-induced folding of models of human telomeric DNA into G-quadruplex structures. Nucleic Acids Research. 36: 4191-203. PMID 18567908 DOI: 10.1093/Nar/Gkn379 |
0.332 |
|
2008 |
Mekmaysy CS, Petraccone L, Garbett NC, Ragazzon PA, Gray R, Trent JO, Chaires JB. Effect of O6-methylguanine on the stability of G-quadruplex DNA Journal of the American Chemical Society. 130: 6710-6711. PMID 18447358 DOI: 10.1021/Ja801976H |
0.359 |
|
2007 |
Ragazzon P, Chaires JB. Use of competition dialysis in the discovery of G-quadruplex selective ligands Methods. 43: 313-323. PMID 17967701 DOI: 10.1016/j.ymeth.2007.08.003 |
0.465 |
|
2007 |
Antonacci C, Chaires JB, Sheardy RD. Biophysical characterization of the human telomeric (TTAGGG)4 repeat in a potassium solution Biochemistry. 46: 4654-4660. PMID 17381076 DOI: 10.1021/Bi602511P |
0.307 |
|
2007 |
Bishop GR, Ren J, Polander BC, Jeanfreau BD, Trent JO, Chaires JB. Energetic basis of molecular recognition in a DNA aptamer Biophysical Chemistry. 126: 165-175. PMID 16914261 DOI: 10.1016/j.bpc.2006.07.009 |
0.307 |
|
2007 |
Freyer MW, Buscaglia R, Cashman D, Hyslop S, Wilson WD, Chaires JB, Lewis EA. Binding of netropsin to several DNA constructs: Evidence for at least two different 1:1 complexes formed from an -AATT-containing ds-DNA construct and a single minor groove binding ligand Biophysical Chemistry. 126: 186-196. PMID 16837123 DOI: 10.1016/J.Bpc.2006.06.009 |
0.321 |
|
2006 |
Chaires JB. A thermodynamic signature for drug-DNA binding mode. Archives of Biochemistry and Biophysics. 453: 26-31. PMID 16730635 DOI: 10.1016/j.abb.2006.03.027 |
0.304 |
|
2005 |
Portugal J, Cashman DJ, Trent JO, Ferrer-Miralles N, Przewloka T, Fokt I, Priebe W, Chaires JB. A new bisintercalating anthracycline with picomolar DNA binding affinity Journal of Medicinal Chemistry. 48: 8209-8219. PMID 16366602 DOI: 10.1021/Jm050902G |
0.302 |
|
2005 |
Li J, Correia JJ, Wang L, Trent JO, Chaires JB. Not so crystal clear: The structure of the human telomere G-quadruplex in solution differs from that present in a crystal Nucleic Acids Research. 33: 4649-4659. PMID 16106044 DOI: 10.1093/Nar/Gki782 |
0.304 |
|
2003 |
Chaires JB. A competition dialysis assay for the study of structure-selective ligand binding to nucleic acids. Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. Unit 8.3. PMID 18428915 |
0.316 |
|
2003 |
Leng F, Chaires JB, Waring MJ. Energetics of echinomycin binding to DNA Nucleic Acids Research. 31: 6191-6197. PMID 14576305 DOI: 10.1093/Nar/Gkg826 |
0.301 |
|
2003 |
Qu X, Ren J, Riccelli PV, Benight AS, Chaires JB. Enthalpy/Entropy Compensation: Influence of DNA Flanking Sequence on the Binding of 7-Amino Actinomycin D to its Primary Binding Site in Short DNA Duplexes Biochemistry. 42: 11960-11967. PMID 14556627 DOI: 10.1021/bi0347813 |
0.3 |
|
2002 |
Carrasco C, Rosu F, Gabelica V, Houssier C, De Pauw E, Garbay-Jaureguiberry C, Roques B, David Wilson W, Chaires JB, Waring MJ, Bailly C. Tight binding of the antitumor drug ditercalinium to quadruplex DNA Chembiochem. 3: 1235-1241. PMID 12465032 DOI: 10.1002/1439-7633(20021202)3:12<1235::Aid-Cbic1235>3.0.Co;2-I |
0.375 |
|
2002 |
Ren J, Qu X, Trent JO, Chaires JB. Tiny telomere DNA Nucleic Acids Research. 30: 2307-2315. PMID 12034817 |
0.352 |
|
2001 |
Alberti P, Ren J, Teulade-Fichou MP, Guittat L, Riou JF, Chaires J, Hélène C, Vigneron JP, Lehn JM, Mergny JL. Interaction of an acridine dimer with DNA quadruplex structures. Journal of Biomolecular Structure & Dynamics. 19: 505-13. PMID 11790148 DOI: 10.1080/07391102.2001.10506758 |
0.408 |
|
2001 |
Priebe W, Fokt I, Przewloka T, Chaires JB, Portugal J, Trent JO. Exploiting anthracycline scaffold for designing DNA-targeting agents Methods in Enzymology. 340: 529-555. PMID 11494869 DOI: 10.1016/S0076-6879(01)40441-1 |
0.301 |
|
2001 |
Chaires JB. Analysis and interpretation of ligand-DNA binding isotherms. Methods in Enzymology. 340: 3-22. PMID 11494856 DOI: 10.1016/S0076-6879(01)40415-0 |
0.308 |
|
2000 |
Bailly C, Goossens JF, Laine W, Anizon F, Prudhomme M, Ren J, Chaires JB. Formaldehyde-induced alkylation of a 2'-aminoglucose rebeccamycin derivative to both A.T and G.C base pairs in DNA. Journal of Medicinal Chemistry. 43: 4711-20. PMID 11101362 DOI: 10.1021/jm0003438 |
0.342 |
|
2000 |
Ren J, Bailly C, Chaires JB. NB-506, an indolocarbazole topoisomerase I inhibitor, binds preferentially to triplex DNA Febs Letters. 470: 355-359. PMID 10745096 DOI: 10.1016/S0014-5793(00)01335-1 |
0.341 |
|
1999 |
Ren J, Chaires JB. Sequence and structural selectivity of nucleic acid binding ligands Biochemistry. 38: 16067-16075. PMID 10587429 DOI: 10.1021/bi992070s |
0.353 |
|
1998 |
Chaires JB. Drug-DNA interactions Current Opinion in Structural Biology. 8: 314-320. PMID 9666327 DOI: 10.1016/S0959-440X(98)80064-X |
0.307 |
|
1997 |
Chaires JB. Energetics of drug-DNA interactions Biopolymers. 44: 201-215. PMID 9591476 |
0.35 |
|
1997 |
Robinson H, Priebe W, Chaires JB, Wang AHJ. Binding of two novel bisdaunorubicins to DNA studied by NMR spectroscopy Biochemistry. 36: 8663-8670. PMID 9289011 DOI: 10.1021/Bi970842J |
0.344 |
|
1997 |
Chaires JB, Leng F, Przewloka T, Fokt I, Ling YH, Perez-Soler R, Priebe W. Structure-based design of a new bisintercalating anthracycline antibiotic Journal of Medicinal Chemistry. 40: 261-266. PMID 9022792 DOI: 10.1021/Jm9607414 |
0.305 |
|
1995 |
Haq I, Lincoln P, Suh D, Norden B, Chowdhry BZ, Chaires JB. Interaction of .DELTA.- and .LAMBDA.-[Ru(phen)2DPPZ]2+ with DNA: A Calorimetric and Equilibrium Binding Study Journal of the American Chemical Society. 117: 4788-4796. DOI: 10.1021/Ja00122A008 |
0.3 |
|
1991 |
Suh D, Sheardy RD, Chaires JB. Unusual binding of ethidium to a deoxyoligonucleotide containing a B-Z junction Biochemistry. 30: 8722-8726. PMID 1888733 DOI: 10.1021/Bi00100A002 |
0.306 |
|
1987 |
Fritzsche H, Wähnert U, Chaires JB, Dattagupta N, Schlessinger FB, Crothers DM. Anthracycline antibiotics. Interaction with DNA and nucleosomes and inhibition of DNA synthesis. Biochemistry. 26: 1996-2000. PMID 3297138 |
0.538 |
|
1985 |
Chaires JB. Long-range allosteric effects on the B to Z equilibrium by daunomycin Biochemistry. 24: 7479-7486. PMID 4084594 |
0.359 |
|
1985 |
Chaires JB, Dattagupta N, Crothers DM. Kinetics of the daunomycin--DNA interaction. Biochemistry. 24: 260-7. PMID 3978073 DOI: 10.1021/Bi00323A004 |
0.526 |
|
1983 |
Chaires JB, Dattagupta N, Crothers DM. Binding of daunomycin to calf thymus nucleosomes. Biochemistry. 22: 284-92. PMID 6824632 DOI: 10.1021/Bi00271A009 |
0.562 |
|
1982 |
Fritzsche H, Triebel H, Chaires JB, Dattagupta N, Crothers DM. Studies on interaction of anthracycline antibiotics and deoxyribonucleic acid: geometry of intercalation of iremycin and daunomycin. Biochemistry. 21: 3940-6. PMID 7126525 DOI: 10.1021/Bi00260A006 |
0.529 |
|
1982 |
Chaires JB, Dattagupta N, Crothers DM. Studies on interaction of anthracycline antibiotics and deoxyribonucleic acid: equilibrium binding studies on interaction of daunomycin with deoxyribonucleic acid. Biochemistry. 21: 3933-40. PMID 7126524 DOI: 10.1021/Bi00260A005 |
0.561 |
|
1982 |
Chaires JB, Dattagupta N, Crothers DM. Self-association of daunomycin. Biochemistry. 21: 3927-32. PMID 7126523 DOI: 10.1021/Bi00260A004 |
0.473 |
|
1982 |
Chaires JB, Dattagupta N, Crothers DM. The interaction of daunomycin with calf-thymus nucleosomes Federation Proceedings. 41: No. 5437. |
0.422 |
|
1982 |
Fritzsche H, Chaires JB, Dattagupta N, Crothers DM. Interaction of anthracycline antibiotics to DNA and nucleosomes: A comparative study Studia Biophysica. 92: 67-68. |
0.485 |
|
1981 |
Chaires JB, Dattagupta N, Crothers DM. The interaction of daunomycin with DNA Biophysical Journal. 33: W-AM-Po81. |
0.489 |
|
1977 |
Chaires JB, Tai M, Huang C, Kegeles G, Infante AA, Wahba AJ. Relaxation kinetics of E. coli ribosomes Biophysical Chemistry. 7: 179-188. PMID 334276 DOI: 10.1016/0301-4622(77)87020-8 |
0.568 |
|
1977 |
Chaires JB, Kegeles G. Sucrose density gradient sedimentation of E. coli ribosomes Biophysical Chemistry. 7: 173-178. PMID 334275 DOI: 10.1016/0301-4622(77)87019-1 |
0.567 |
|
1975 |
Chaires JB, Kegeles G, Wahba AJ. Relaxation kinetics of E coli ribosomes: evidence for the reaction of 30S . IF3 complex with 50S ribosomal subunits. Biophysical Chemistry. 9: 405-12. PMID 16997206 |
0.594 |
|
1975 |
Chaires JB, Kegeles G, Wahba AJ. Relaxation kinetics of E coli ribosomes: evidence for the reaction of 30S · IF3 complex with 50s ribosomal subunits Biophysical Chemistry. 9: 405-412. PMID 380673 DOI: 10.1016/0301-4622(75)80056-1 |
0.595 |
|
1972 |
Noller HF, Chaires JB. Functional modification of 16S ribosomal RNA by kethoxal. Proceedings of the National Academy of Sciences of the United States of America. 69: 3115-8. PMID 4564202 DOI: 10.1073/Pnas.69.11.3115 |
0.448 |
|
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