Jonathan J Miner, MD/PhD - Publications

Affiliations: 
2017-2021 Medicine Washington University School of Medicine, St. Louis, MO, United States 
 2021- Medicine University of Pennsylvania, Philadelphia, PA, United States 
Area:
Rare diseases, gene therapies, TREX1, RVCL, STING, SAVI, host-microbe interactions, cell-intrinsic innate immunity, autoimmunity, virology, rheumatology
Website:
https://www.med.upenn.edu/rvcl/

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Chauvin SD, Ando S, Holley JA, Sugie A, Zhao FR, Poddar S, Kato R, Miner CA, Nitta Y, Krishnamurthy SR, Saito R, Ning Y, Hatano Y, Kitahara S, Koide S, ... ... Miner JJ, et al. Inherited C-terminal TREX1 variants disrupt homology-directed repair to cause senescence and DNA damage phenotypes in Drosophila, mice, and humans. Nature Communications. 15: 4696. PMID 38824133 DOI: 10.1038/s41467-024-49066-7  0.721
2023 Chauvin SD, Stinson WA, Platt DJ, Poddar S, Miner JJ. Regulation of cGAS and STING signaling during inflammation and infection. The Journal of Biological Chemistry. 104866. PMID 37247757 DOI: 10.1016/j.jbc.2023.104866  0.739
2022 Stinson WA, Miner CA, Zhao FR, Lundgren AJ, Poddar S, Miner JJ. The IFN-γ receptor promotes immune dysregulation and disease in STING gain-of-function mice. Jci Insight. 7. PMID 36073546 DOI: 10.1172/jci.insight.155250  0.782
2021 Platt DJ, Lawrence D, Rodgers R, Schriefer L, Qian W, Miner CA, Menos AM, Kennedy EA, Peterson ST, Stinson WA, Baldridge MT, Miner JJ. Transferrable protection by gut microbes against STING-associated lung disease. Cell Reports. 35: 109113. PMID 33979608 DOI: 10.1016/j.celrep.2021.109113  0.788
2021 Walker FC, Hassan E, Peterson ST, Rodgers R, Schriefer LA, Thompson CE, Li Y, Kalugotla G, Blum-Johnston C, Lawrence D, McCune BT, Graziano VR, Lushniak L, Lee S, Roth AN, ... ... Miner JJ, et al. Norovirus evolution in immunodeficient mice reveals potentiated pathogenicity via a single nucleotide change in the viral capsid. Plos Pathogens. 17: e1009402. PMID 33705489 DOI: 10.1371/journal.ppat.1009402  0.663
2021 Rhee RL, Lu J, Bittinger K, Lee JJ, Mattei LM, Sreih AG, Chou S, Miner JJ, Cohen NA, Kelly BJ, Lee H, Grayson PC, Collman RG, Merkel PA. Dynamic Changes in the Nasal Microbiome Associated with Disease Activity in Patients with Granulomatosis with Polyangiitis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 33682371 DOI: 10.1002/art.41723  0.23
2020 Miner JJ, Platt DJ, Ghaznavi CM, Chandra P, Santeford A, Menos AM, Dong Z, Wang ER, Qian W, Karozichian ES, Philips JA, Apte RS. HSV-1 and Zika Virus but Not SARS-CoV-2 Replicate in the Human Cornea and Are Restricted by Corneal Type III Interferon. Cell Reports. 33: 108339. PMID 33147451 DOI: 10.1016/j.celrep.2020.108339  0.793
2020 Ford AL, Chin VW, Fellah S, Binkley MM, Bodin AM, Balasetti V, Taiwo Y, Kang P, Lin D, Jen JC, Grand G, Bogacki M, Liszewski MK, Hourcade D, Chen Y, ... ... Miner JJ, et al. Lesion evolution and neurodegeneration in RVCL-S: A monogenic microvasculopathy. Neurology. PMID 32887784 DOI: 10.1212/Wnl.0000000000010659  0.19
2020 Platt DJ, Miner JJ. Immunopathology of Zika virus infection. Advances in Virus Research. 107: 223-246. PMID 32711730 DOI: 10.1016/bs.aivir.2020.06.007  0.762
2020 Bennion BG, Croft CA, Ai TL, Qian W, Menos AM, Miner CA, Frémond ML, Doisne JM, Andhey PS, Platt DJ, Bando JK, Wang ER, Luksch H, Molina TJ, Roberson EDO, ... ... Miner JJ, et al. STING Gain-of-Function Disrupts Lymph Node Organogenesis and Innate Lymphoid Cell Development in Mice. Cell Reports. 31: 107771. PMID 32553167 DOI: 10.1016/j.celrep.2020.107771  0.773
2020 Balka KR, Louis C, Saunders TL, Smith AM, Calleja DJ, D'Silva DB, Moghaddas F, Tailler M, Lawlor KE, Zhan Y, Burns CJ, Wicks IP, Miner JJ, Kile BT, Masters SL, et al. TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells. Cell Reports. 31: 107492. PMID 32268090 DOI: 10.1016/j.celrep.2020.03.056  0.33
2020 Ma H, Qian W, Bambouskova M, Collins PL, Porter SI, Byrum AK, Zhang R, Artyomov M, Oltz EM, Mosammaparast N, Miner JJ, Diamond MS. Barrier-to-Autointegration Factor 1 Protects against a Basal cGAS-STING Response. Mbio. 11. PMID 32156810 DOI: 10.1128/Mbio.00136-20  0.54
2020 Casazza RL, Lazear HM, Miner JJ. Protective and Pathogenic Effects of Interferon Signaling During Pregnancy. Viral Immunology. 33: 3-11. PMID 31545139 DOI: 10.1089/vim.2019.0076  0.38
2019 Qian W, Miner CA, Ingle H, Platt DJ, Baldridge MT, Miner JJ. A human STAT1 gain-of-function mutation impairs CD8 T cell responses against gammaherpesvirus-68. Journal of Virology. PMID 31315996 DOI: 10.1128/JVI.00307-19  0.802
2019 Ingle H, Lee S, Ai T, Orvedahl A, Rodgers R, Zhao G, Sullender M, Peterson ST, Locke M, Liu TC, Yokoyama CC, Sharp B, Schultz-Cherry S, Miner JJ, Baldridge MT. Viral complementation of immunodeficiency confers protection against enteric pathogens via interferon-λ. Nature Microbiology. PMID 30936486 DOI: 10.1038/S41564-019-0416-7  0.651
2019 Wu J, Chen YJ, Dobbs N, Sakai T, Liou J, Miner JJ, Yan N. STING-mediated disruption of calcium homeostasis chronically activates ER stress and primes T cell death. The Journal of Experimental Medicine. PMID 30886058 DOI: 10.1084/Jem.20182192  0.334
2019 Luksch H, Stinson WA, Platt DJ, Qian W, Kalugotla G, Miner CA, Bennion BG, Gerbaulet A, Rösen-Wolff A, Miner JJ. STING-associated lung disease in mice relies on T cells but not type I interferon. The Journal of Allergy and Clinical Immunology. PMID 30772497 DOI: 10.1016/j.jaci.2019.01.044  0.794
2019 Paley MA, Karacal H, Rao PK, Margolis TP, Miner JJ. Tofacitinib for refractory uveitis and scleritis. American Journal of Ophthalmology Case Reports. 13: 53-55. PMID 30582071 DOI: 10.1016/J.Ajoc.2018.12.001  0.199
2018 Bennion BG, Ingle H, Ai TL, Miner CA, Platt DJ, Smith AM, Baldridge MT, Miner JJ. A human gain-of-function STING mutation causes immunodeficiency and gammaherpesvirus-induced pulmonary fibrosis in mice. Journal of Virology. PMID 30463976 DOI: 10.1128/JVI.01806-18  0.817
2018 MacDuff DA, Baldridge MT, Qaqish AM, Nice TJ, Darbandi AD, Hartley VL, Peterson ST, Miner JJ, Iwai K, Virgin HW. HOIL1 is essential for the induction of type I and III interferons by MDA5 and regulates persistent murine norovirus infection. Journal of Virology. PMID 30209176 DOI: 10.1128/Jvi.01368-18  0.701
2018 Hansen AL, Buchan GJ, Rühl M, Mukai K, Salvatore SR, Ogawa E, Andersen SD, Iversen MB, Thielke AL, Gunderstofte C, Motwani M, Møller CT, Jakobsen AS, Fitzgerald KA, Roos J, ... ... Miner JJ, et al. Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 30061387 DOI: 10.1073/Pnas.1806239115  0.402
2018 Platt DJ, Smith AM, Arora N, Diamond MS, Coyne CB, Miner JJ. Zika virus-related neurotropic flaviviruses infect human placental explants and cause fetal demise in mice. Science Translational Medicine. 10. PMID 29386359 DOI: 10.1126/Scitranslmed.Aao7090  0.802
2018 Miner JJ, Lenschow DJ. Lessons learned from Chikungunya in the Americas. Arthritis & Rheumatology (Hoboken, N.J.). PMID 29361204 DOI: 10.1002/Art.40421  0.319
2017 Platt DJ, Miner JJ. Consequences of congenital Zika virus infection. Current Opinion in Virology. 27: 1-7. PMID 29080429 DOI: 10.1016/j.coviro.2017.09.005  0.782
2017 Warner JD, Irizarry-Caro RA, Bennion BG, Ai TL, Smith AM, Miner CA, Sakai T, Gonugunta VK, Wu J, Platt DJ, Yan N, Miner JJ. STING-associated vasculopathy develops independently of IRF3 in mice. The Journal of Experimental Medicine. PMID 28951494 DOI: 10.1084/jem.20171351  0.788
2017 Jagger BW, Miner JJ, Cao B, Arora N, Smith AM, Kovacs A, Mysorekar IU, Coyne CB, Diamond MS. Gestational Stage and IFN-λ Signaling Regulate ZIKV Infection In Utero. Cell Host & Microbe. 22: 366-376.e3. PMID 28910635 DOI: 10.1016/J.Chom.2017.08.012  0.552
2017 Miner JJ. Congenital Zika virus infection: More than just microcephaly. Science Translational Medicine. 9. PMID 28592568 DOI: 10.1126/scitranslmed.aan8195  0.367
2017 Miner JJ, Diamond MS. Dengue Antibodies, then Zika: A Fatal Sequence in Mice. Immunity. 46: 771-773. PMID 28514683 DOI: 10.1016/J.Immuni.2017.04.023  0.56
2017 Miner JJ. Defeating Zika. Science Translational Medicine. 9. PMID 28446685 DOI: 10.1126/scitranslmed.aan2785  0.359
2017 Miner JJ. Gamete fusion gone viral. Science Translational Medicine. 9. PMID 28298425 DOI: 10.1126/scitranslmed.aam9866  0.342
2017 Miner JJ, Diamond MS. Zika Virus Pathogenesis and Tissue Tropism. Cell Host & Microbe. 21: 134-142. PMID 28182948 DOI: 10.1016/J.Chom.2017.01.004  0.489
2017 Burt FJ, Chen W, Miner JJ, Lenschow DJ, Merits A, Schnettler E, Kohl A, Rudd PA, Taylor A, Herrero LJ, Zaid A, Ng LF, Mahalingam S. Chikungunya virus: an update on the biology and pathogenesis of this emerging pathogen. The Lancet. Infectious Diseases. PMID 28159534 DOI: 10.1016/S1473-3099(16)30385-1  0.395
2017 Miner JJ, Cook LE, Hong JP, Smith AM, Richner JM, Shimak RM, Young AR, Monte K, Poddar S, Crowe JE, Lenschow DJ, Diamond MS. Therapy with CTLA4-Ig and an antiviral monoclonal antibody controls chikungunya virus arthritis. Science Translational Medicine. 9. PMID 28148840 DOI: 10.1126/Scitranslmed.Aah3438  0.76
2016 Miner JJ, Sene A, Richner JM, Smith AM, Santeford A, Ban N, Weger-Lucarelli J, Manzella F, Rückert C, Govero J, Noguchi KK, Ebel GD, Diamond MS, Apte RS. Zika Virus Infection in Mice Causes Panuveitis with Shedding of Virus in Tears. Cell Reports. PMID 27612415 DOI: 10.1016/J.Celrep.2016.08.079  0.58
2016 Zhang R, Miner JJ, Gorman MJ, Rausch K, Ramage H, White JP, Zuiani A, Zhang P, Fernandez E, Zhang Q, Dowd KA, Pierson TC, Cherry S, Diamond MS. A CRISPR screen defines a signal peptide processing pathway required by flaviviruses. Nature. 535: 164-168. PMID 27383988 DOI: 10.1038/Nature18625  0.511
2016 Schmid ET, Pang IK, Carrera Silva EA, Bosurgi L, Miner JJ, Diamond MS, Iwasaki A, Rothlin CV. AXL receptor tyrosine kinase is required for T cell priming and antiviral immunity. Elife. 5. PMID 27350258 DOI: 10.7554/Elife.12414  0.556
2016 Miner JJ, Cao B, Govero J, Smith AM, Fernandez E, Cabrera OH, Garber C, Noll M, Klein RS, Noguchi KK, Mysorekar IU, Diamond MS. Zika Virus Infection during Pregnancy in Mice Causes Placental Damage and Fetal Demise. Cell. PMID 27180225 DOI: 10.1016/J.Cell.2016.05.008  0.567
2016 Miner JJ, Diamond MS. Understanding How Zika Virus Enters and Infects Neural Target Cells. Cell Stem Cell. 18: 559-60. PMID 27152436 DOI: 10.1016/J.Stem.2016.04.009  0.479
2016 Lazear HM, Govero J, Smith AM, Platt DJ, Fernandez E, Miner JJ, Diamond MS. A Mouse Model of Zika Virus Pathogenesis. Cell Host & Microbe. PMID 27066744 DOI: 10.1016/J.Chom.2016.03.010  0.807
2015 Miner JJ, Diamond MS. Mechanisms of restriction of viral neuroinvasion at the blood-brain barrier. Current Opinion in Immunology. 38: 18-23. PMID 26590675 DOI: 10.1016/J.Coi.2015.10.008  0.496
2015 Miner JJ, Daniels BP, Shrestha B, Proenca-Modena JL, Lew ED, Lazear HM, Gorman MJ, Lemke G, Klein RS, Diamond MS. The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-brain barrier integrity. Nature Medicine. PMID 26523970 DOI: 10.1038/Nm.3974  0.545
2015 Miner JJ, Aw Yeang HX, Fox JM, Taffner S, Malkova ON, Oh ST, Kim AH, Diamond MS, Lenschow DJ, Yokoyama WM. Chikungunya viral arthritis in the United States: a mimic of seronegative rheumatoid arthritis. Arthritis & Rheumatology (Hoboken, N.J.). 67: 1214-20. PMID 25605621 DOI: 10.1002/Art.39027  0.467
2014 Thackray LB, Shrestha B, Richner JM, Miner JJ, Pinto AK, Lazear HM, Gale M, Diamond MS. Interferon regulatory factor 5-dependent immune responses in the draining lymph node protect against West Nile virus infection. Journal of Virology. 88: 11007-21. PMID 25031348 DOI: 10.1128/Jvi.01545-14  0.609
2014 Miner JJ, Diamond MS. MDA5 and autoimmune disease. Nature Genetics. 46: 418-9. PMID 24769716 DOI: 10.1038/Ng.2959  0.489
2014 Miner JJ, Kim AH. Cardiac manifestations of systemic lupus erythematosus. Rheumatic Diseases Clinics of North America. 40: 51-60. PMID 24268009 DOI: 10.1016/j.rdc.2013.10.003  0.235
2011 Miner JJ, Shao B, Wang Y, Chichili GR, Liu Z, Klopocki AG, Yago T, McDaniel JM, Rodgers W, Xia L, McEver RP. Cytoplasmic domain of P-selectin glycoprotein ligand-1 facilitates dimerization and export from the endoplasmic reticulum. The Journal of Biological Chemistry. 286: 9577-86. PMID 21220419 DOI: 10.1074/Jbc.M110.208777  0.758
2010 Liu Z, Miner JJ, Yago T, Yao L, Lupu F, Xia L, McEver RP. Differential regulation of human and murine P-selectin expression and function in vivo. The Journal of Experimental Medicine. 207: 2975-87. PMID 21149548 DOI: 10.1084/Jem.20101545  0.696
2010 Yago T, Fu J, McDaniel JM, Miner JJ, McEver RP, Xia L. Core 1-derived O-glycans are essential E-selectin ligands on neutrophils. Proceedings of the National Academy of Sciences of the United States of America. 107: 9204-9. PMID 20439727 DOI: 10.1073/Pnas.1003110107  0.653
2010 Yago T, Shao B, Miner JJ, Yao L, Klopocki AG, Maeda K, Coggeshall KM, McEver RP. E-selectin engages PSGL-1 and CD44 through a common signaling pathway to induce integrin alphaLbeta2-mediated slow leukocyte rolling. Blood. 116: 485-94. PMID 20299514 DOI: 10.1182/Blood-2009-12-259556  0.75
2009 Stowell SR, Karmakar S, Arthur CM, Ju T, Rodrigues LC, Riul TB, Dias-Baruffi M, Miner J, McEver RP, Cummings RD. Galectin-1 induces reversible phosphatidylserine exposure at the plasma membrane. Molecular Biology of the Cell. 20: 1408-18. PMID 19116313 DOI: 10.1091/Mbc.E08-07-0786  0.523
2008 Yago T, Lou J, Wu T, Yang J, Miner JJ, Coburn L, López JA, Cruz MA, Dong JF, McIntire LV, McEver RP, Zhu C. Platelet glycoprotein Ibα forms catch bonds with human WT vWF but not with type 2B von Willebrand disease vWF Journal of Clinical Investigation. 118: 3195-3207. PMID 18725999 DOI: 10.1172/Jci35754  0.52
2008 Miner JJ, Xia L, Yago T, Kappelmayer J, Liu Z, Klopocki AG, Shao B, McDaniel JM, Setiadi H, Schmidtke DW, McEver RP. Separable requirements for cytoplasmic domain of PSGL-1 in leukocyte rolling and signaling under flow. Blood. 112: 2035-45. PMID 18550846 DOI: 10.1182/Blood-2008-04-149468  0.771
2007 Miner J, Hoffhines A. The discovery of aspirin's antithrombotic effects. Texas Heart Institute Journal. 34: 179-86. PMID 17622365  0.22
2005 Miner J, Gillan MM, Alex P, Centola M. Steroid-refractory ulcerative colitis treated with corticosteriods, metronidazole and vancomycin: A case report Bmc Gastroenterology. 5. PMID 15667650 DOI: 10.1186/1471-230X-5-3  0.303
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