Year |
Citation |
Score |
2017 |
Sharma S, Guru SK, Manda S, Kumar A, Mintoo MJ, Prasad VD, Sharma PR, Mondhe DM, Bharate SB, Bhushan S. A marine sponge alkaloid derivative 4-chloro fascaplysin inhibits tumor growth and VEGF mediated angiogenesis by disrupting PI3K/Akt/mTOR signaling cascade. Chemico-Biological Interactions. 275: 47-60. PMID 28756150 DOI: 10.1016/j.cbi.2017.07.017 |
0.563 |
|
2015 |
Manda S, Sharma S, Wani A, Joshi P, Kumar V, Guru SK, Bharate SS, Bhushan S, Vishwakarma RA, Kumar A, Bharate SB. Discovery of a marine-derived bis-indole alkaloid fascaplysin, as a new class of potent P-glycoprotein inducer and establishment of its structure-activity relationship. European Journal of Medicinal Chemistry. 107: 1-11. PMID 26560048 DOI: 10.1016/J.Ejmech.2015.10.049 |
0.563 |
|
2015 |
Kumar S, Guru SK, Pathania AS, Manda S, Kumar A, Bharate SB, Vishwakarma RA, Malik F, Bhushan S. Fascaplysin induces caspase mediated crosstalk between apoptosis and autophagy through the inhibition of PI3K/AKT/mTOR signaling cascade in human leukemia HL-60 cells. Journal of Cellular Biochemistry. 116: 985-97. PMID 25561006 DOI: 10.1002/Jcb.25053 |
0.563 |
|
2014 |
Mahale S, Bharate SB, Manda S, Joshi P, Bharate SS, Jenkins PR, Vishwakarma RA, Chaudhuri B. Biphenyl-4-carboxylic acid [2-(1H-indol-3-yl)-ethyl]-methylamide (CA224), a nonplanar analogue of fascaplysin, inhibits Cdk4 and tubulin polymerization: evaluation of in vitro and in vivo anticancer activity. Journal of Medicinal Chemistry. 57: 9658-72. PMID 25368960 DOI: 10.1021/Jm5014743 |
0.589 |
|
2014 |
Manda S, Khan SI, Jain SK, Mohammed S, Tekwani BL, Khan IA, Vishwakarma RA, Bharate SB. Synthesis, antileishmanial and antitrypanosomal activities of N-substituted tetrahydro-β-carbolines. Bioorganic & Medicinal Chemistry Letters. 24: 3247-50. PMID 24980054 DOI: 10.1016/J.Bmcl.2014.06.030 |
0.58 |
|
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