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Neal J. Zondlo - Publications

Affiliations: 
Chemistry and Biochemistry University of Delaware, Newark, DE, United States 
Area:
molecular recognition
Website:
http://www.chem.udel.edu/chemistry/faculty/neal-j-zondlo-associate-professor
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42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Pandey AK, Ganguly HK, Sinha SK, Daniels KE, Yap GPA, Patel S, Zondlo NJ. An Inherent Difference between Serine and Threonine Phosphorylation: Phosphothreonine Strongly Prefers a Highly Ordered, Compact, Cyclic Conformation. Acs Chemical Biology. PMID 37595155 DOI: 10.1021/acschembio.3c00068  0.372
2023 Bhatt MR, Zondlo NJ. Synthesis and conformational preferences of peptides and proteins with cysteine sulfonic acid. Organic & Biomolecular Chemistry. 21: 2779-2800. PMID 36920119 DOI: 10.1039/d3ob00179b  0.34
2020 Tressler CM, Zondlo NJ. Perfluoro--Butyl Hydroxyprolines as Sensitive, Conformationally Responsive Molecular Probes: Detection of Protein Kinase Activity by F NMR. Acs Chemical Biology. PMID 32125821 DOI: 10.1021/Acschembio.0C00131  0.464
2020 Urmey AR, Zondlo NJ. Cysteine oxidation to the sulfinic acid induces oxoform-specific lanthanide binding and fluorescence in a designed peptide. Free Radical Biology & Medicine. PMID 32097680 DOI: 10.1016/J.Freeradbiomed.2020.02.020  0.407
2020 Urmey AR, Zondlo NJ. Synthesis of peptides with cysteine sulfinic acid via the cysteine methoxybenzyl sulfone Peptide Science. 112. DOI: 10.1002/Pep2.24137  0.405
2019 Urmey AR, Zondlo NJ. Structural preferences of cysteine sulfinic acid: The sulfinate engages in multiple local interactions with the peptide backbone. Free Radical Biology & Medicine. PMID 31883974 DOI: 10.1016/J.Freeradbiomed.2019.12.030  0.42
2019 Costantini NV, Ganguly HK, Martin MI, Wenzell NA, Yap GPA, Zondlo NJ. The distinct conformational landscapes of 4S-substituted prolines that promote an endo ring pucker. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31237705 DOI: 10.1002/Chem.201902382  0.365
2019 Urmey AR, Zondlo NJ. Design of a Protein Motif Responsive to Tyrosine Nitration and an Encoded Turn-Off Sensor of Tyrosine Nitration. Biochemistry. PMID 31140788 DOI: 10.1021/Acs.Biochem.9B00334  0.446
2019 Gao F, Thornley BS, Tressler CM, Naduthambi D, Zondlo NJ. Phosphorylation-dependent protein design: design of a minimal protein kinase-inducible domain. Organic & Biomolecular Chemistry. PMID 30942803 DOI: 10.1039/C9Ob00502A  0.481
2018 Wenzell NA, Ganguly HK, Pandey AK, Bhatt MR, Yap GPA, Zondlo NJ. Electronic and steric control of n→π* interactions: stabilization of the α-helix conformation without a hydrogen bond. Chembiochem : a European Journal of Chemical Biology. PMID 30548564 DOI: 10.1002/Cbic.201800785  0.365
2018 Scheuermann MJ, Forbes CR, Zondlo NJ. Redox-Responsive Protein Design: Design of a Small Protein Motif Dependent on Glutathionylation. Biochemistry. PMID 30511831 DOI: 10.1021/Acs.Biochem.8B00973  0.408
2017 Tressler CM, Zondlo NJ. Perfluoro-tert-butyl Homoserine is a Helix-Promoting, Highly Fluorinated, NMR-Sensitive Aliphatic Amino Acid: Detection of the Estrogen Receptor•Coactivator Protein-Protein Interaction by 19F NMR. Biochemistry. PMID 28165218 DOI: 10.1021/Acs.Biochem.6B01020  0.416
2016 Tressler CM, Zondlo NJ. Synthesis of Perfluoro-tert-butyl Tyrosine, for Application in (19)F NMR, via a Diazonium-Coupling Reaction. Organic Letters. 18: 6240-6243. PMID 27978684 DOI: 10.1021/Acs.Orglett.6B02858  0.382
2016 Forbes CR, Pandey AK, Ganguly HK, Yap GP, Zondlo NJ. 4R- and 4S-iodophenyl hydroxyproline, 4R-pentynoyl hydroxyproline, and S-propargyl-4-thiolphenylalanine: conformationally biased and tunable amino acids for bioorthogonal reactions. Organic & Biomolecular Chemistry. PMID 26806113 DOI: 10.1039/C5Ob02473K  0.401
2014 Pandey AK, Thomas KM, Forbes CR, Zondlo NJ. Tunable control of polyproline helix (PPII) structure via aromatic electronic effects: an electronic switch of polyproline helix. Biochemistry. 53: 5307-14. PMID 25075447 DOI: 10.1021/Bi500696K  0.369
2014 Tressler CM, Zondlo NJ. (2 S,4 R)- and (2 S,4 S)-Perfluoro- tert -butyl 4-hydroxyproline: Two conformationally distinct proline amino acids for sensitive application in 19F NMR Journal of Organic Chemistry. 79: 5880-5886. PMID 24870929 DOI: 10.1021/Jo5008674  0.406
2014 Elbaum MB, Zondlo NJ. OGlcNAcylation and phosphorylation have similar structural effects in α-helices: Post-translational modifications as inducible start and stop signals in α-helices, with greater structural effects on threonine modification Biochemistry. 53: 2242-2260. PMID 24641765 DOI: 10.1021/Bi500117C  0.397
2014 Brister MA, Pandey AK, Bielska AA, Zondlo NJ. OGlcNAcylation and phosphorylation have opposing structural effects in tau: phosphothreonine induces particular conformational order. Journal of the American Chemical Society. 136: 3803-16. PMID 24559475 DOI: 10.1021/Ja407156M  0.417
2014 Zondlo NJ, Pandey A, Ganguly H, Elbaum M, Brister M. P4-258: ON THE NATURE OF THE TAU R406W MUTATION: INCREASED CIS PSER404-PRO405 AMIDE BOND IN TAU R406W DUE TO A PHOSPHORYLATION-SENSITIVE CIS-PROLINE-AROMATIC INTERACTION Alzheimer's & Dementia. 10: P879-P880. DOI: 10.1016/J.Jalz.2014.07.029  0.325
2013 Naduthambi D, Bhor S, Elbaum MB, Zondlo NJ. Synthesis of a tetrasubstituted tetrahydronaphthalene scaffold for α-helix mimicry via a MgBr2-catalyzed Friedel-Crafts epoxide cycloalkylation. Organic Letters. 15: 4892-5. PMID 24016333 DOI: 10.1021/Ol402334J  0.333
2013 Pandey AK, Naduthambi D, Thomas KM, Zondlo NJ. Proline editing: A general and practical approach to the synthesis of functionally and structurally diverse peptides. Analysis of steric versus stereoelectronic effects of 4-substituted prolines on conformation within peptides Journal of the American Chemical Society. 135: 4333-4363. PMID 23402492 DOI: 10.1021/Ja3109664  0.443
2013 Zondlo NJ. Aromatic-proline interactions: Electronically tunable CH/π interactions Accounts of Chemical Research. 46: 1039-1049. PMID 23148796 DOI: 10.1021/Ar300087Y  0.384
2012 Brown AM, Zondlo NJ. A propensity scale for type II polyproline helices (PPII): aromatic amino acids in proline-rich sequences strongly disfavor PPII due to proline-aromatic interactions. Biochemistry. 51: 5041-51. PMID 22667692 DOI: 10.1021/Bi3002924  0.42
2012 Forbes CR, Zondlo NJ. Synthesis of thiophenylalanine-containing peptides via Cu(I)-mediated cross-coupling Organic Letters. 14: 464-467. PMID 22224916 DOI: 10.1021/Ol202947F  0.374
2012 Balakrishnan S, Scheuermann MJ, Zondlo NJ. Arginine mimetics using α-guanidino acids: introduction of functional groups and stereochemistry adjacent to recognition guanidiniums in peptides. Chembiochem : a European Journal of Chemical Biology. 13: 259-70. PMID 22213184 DOI: 10.1002/Cbic.201100638  0.612
2011 Zondlo N, Gao F. P4-330: Fluorescence imaging of cdk5, GSK-3b, MARK, and Fyn kinase activities in solution and in cells via novel encodable sensors Alzheimer's & Dementia. 7: e25-e26. DOI: 10.1016/J.Jalz.2011.09.075  0.355
2011 Zondlo N, Brister M, Bielska A. P4-329: Opposing structural effects of glycosylation and phosphorylation on tau Alzheimer's & Dementia. 7: e25-e25. DOI: 10.1016/J.Jalz.2011.09.074  0.308
2010 Zondlo NJ. Non-covalent interactions: Fold globally, bond locally Nature Chemical Biology. 6: 567-568. PMID 20644541 DOI: 10.1038/Nchembio.413  0.306
2010 Am Ende CW, Meng HY, Ye M, Pandey AK, Zondlo NJ. Design of lanthanide fingers: Compact lanthanide-binding metalloproteins Chembiochem. 11: 1738-1747. PMID 20623571 DOI: 10.1002/Cbic.201000056  0.39
2010 Zondlo SC, Gao F, Zondlo NJ. Design of an encodable tyrosine kinase-inducible domain: Detection of tyrosine kinase activity by terbium luminescence Journal of the American Chemical Society. 132: 5619-5621. PMID 20361796 DOI: 10.1021/Ja100862U  0.432
2010 Zondlo NJ, Gao F, White S. O4-04-06: Imaging cdk5, GSK-3, and MARK kinase activities with a small, genetically encoded fluorescent sensor Alzheimer's & Dementia. 6: S156-S156. DOI: 10.1016/J.Jalz.2010.05.486  0.355
2009 Zondlo NJ, Gao F. P4-152: Imaging CDK5 kinase activity with a small, genetically encodable fluorescent sensor Alzheimer's & Dementia. 5: P476-P476. DOI: 10.1016/J.Jalz.2009.04.719  0.358
2008 Balakrishnan S, Zhao C, Zondlo NJ. ChemInform Abstract: Convergent and Stereospecific Synthesis of Molecules Containing α-Functionalized Guanidiniums via α-Guanidino Acids. Cheminform. 39. DOI: 10.1002/chin.200817052  0.484
2007 Balakrishnan S, Zhao C, Zondlo NJ. Convergent and stereospecific synthesis of molecules containing alpha-functionalized guanidiniums via alpha-guanidino acids. The Journal of Organic Chemistry. 72: 9834-7. PMID 17979289 DOI: 10.1021/Jo701766C  0.526
2006 Zondlo SC, Lee AE, Zondlo NJ. Determinants of specificity of MDM2 for the activation domains of p53 and p65: Proline27 disrupts the MDM2-binding motif of p53 Biochemistry. 45: 11945-11957. PMID 17002294 DOI: 10.1021/Bi060309G  0.305
2006 Naduthambi D, Zondlo NJ. Stereoelectronic tuning of the structure and stability of the Trp cage miniprotein Journal of the American Chemical Society. 128: 12430-12431. PMID 16984189 DOI: 10.1021/Ja0648458  0.42
2006 Balakrishnan S, Zondlo NJ. Design of a protein kinase-inducible domain. Journal of the American Chemical Society. 128: 5590-1. PMID 16637598 DOI: 10.1021/Ja057692H  0.585
2006 Bielska AA, Zondlo NJ. Hyperphosphorylation of tau induces local polyproline II helix Biochemistry. 45: 5527-5537. PMID 16634634 DOI: 10.1021/Bi052662C  0.426
2006 Thomas KM, Naduthambi D, Zondlo NJ. Electronic control of amide cis-trans isomerism via the aromatic-prolyl interaction Journal of the American Chemical Society. 128: 2216-2217. PMID 16478167 DOI: 10.1021/Ja057901Y  0.345
2006 Meng HY, Thomas KM, Lee AE, Zondlo NJ. Effects of i and i+3 residue identity on cis-trans isomerism of the aromatici+1-prolyli+2 amide bond: Implications for type VI β-turn formation Biopolymers - Peptide Science Section. 84: 192-204. PMID 16208767 DOI: 10.1002/Bip.20382  0.378
2005 Thomas KM, Naduthambi D, Tririya G, Zondlo NJ. Proline editing: A divergent strategy for the synthesis of conformationally diverse peptides Organic Letters. 7: 2397-2400. PMID 15932207 DOI: 10.1021/Ol0506720  0.405
1999 Zondlo NJ, Schepartz A. Highly specific DNA recognition by a designed miniature protein [2] Journal of the American Chemical Society. 121: 6938-6939. DOI: 10.1021/Ja990968Z  0.532
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