Year |
Citation |
Score |
2023 |
LaLone V, Smith D, Diaz-Espinosa J, Rosania GR. Quantitative Raman Chemical Imaging of Intracellular Drug-Membrane Aggregates and Small Molecule Drug Precipitates In Cytoplasmic Organelles. Advanced Drug Delivery Reviews. 115107. PMID 37769851 DOI: 10.1016/j.addr.2023.115107 |
0.821 |
|
2023 |
Willmer AR, Diaz-Espinosa J, Zhou A, Stringer KA, Rosania GR. Distinguishing the Concentration- vs. Bioaccumulation-Dependent Immunological and Metabolic Effects of Clofazimine. Pharmaceutics. 15. PMID 37765318 DOI: 10.3390/pharmaceutics15092350 |
0.304 |
|
2022 |
Willmer AR, Nie J, George De la Rosa MV, Wen W, Dunne S, Rosania GR. Molecular design of a pathogen activated, self-assembling mechanopharmaceutical device. Journal of Controlled Release : Official Journal of the Controlled Release Society. 347: 620-631. PMID 35623493 DOI: 10.1016/j.jconrel.2022.05.029 |
0.356 |
|
2021 |
Dunne S, Willmer AR, Swanson R, Almeida D, Ammerman NC, Stringer KA, Capparelli EV, Rosania GR. Quantitative Analysis of the Phase Transition Mechanism Underpinning the Systemic Self-Assembly of a Mechanopharmaceutical Device. Pharmaceutics. 14. PMID 35056910 DOI: 10.3390/pharmaceutics14010015 |
0.303 |
|
2020 |
Rzeczycki P, Junginger L, Goldman S, Lammlin L, Rasner C, Redding S, Rosania G, Clauw D, Maerz T. Pain, inflammation, and the endocannabinoid system in murine post-traumatic osteoarthritis Osteoarthritis and Cartilage. 28: S82-S83. DOI: 10.1016/j.joca.2020.02.126 |
0.714 |
|
2019 |
Tan JWY, Murashov MD, Rosania GR, Wang X. Photoacoustic imaging of clofazimine hydrochloride nanoparticle accumulation in cancerous vs normal prostates. Plos One. 14: e0219655. PMID 31306463 DOI: 10.1371/Journal.Pone.0219655 |
0.748 |
|
2019 |
LaLone V, Fawaz MV, Morales-Mercado J, Mourão MA, Snyder CS, Kim SY, Lieberman AP, Tuteja A, Mehta G, Standiford TJ, Raghavendran K, Shedden K, Schwendeman A, Stringer KA, Rosania GR. Inkjet-printed micro-calibration standards for ultraquantitative Raman spectral cytometry. The Analyst. PMID 31116195 DOI: 10.1039/C9An00500E |
0.791 |
|
2019 |
Hong X, Rzeczycki PM, Keswani RK, Murashov MD, Fan Z, Deng CX, Rosania GR. Acoustic tweezing cytometry for mechanical phenotyping of macrophages and mechanopharmaceutical cytotripsy. Scientific Reports. 9: 5702. PMID 30952950 DOI: 10.1038/S41598-019-42180-3 |
0.799 |
|
2018 |
Murashov MD, Diaz-Espinosa J, LaLone V, Tan JWY, Laza R, Wang X, Stringer KA, Rosania GR. Synthesis and Characterization of a Biomimetic Formulation of Clofazimine Hydrochloride Microcrystals for Parenteral Administration. Pharmaceutics. 10. PMID 30453628 DOI: 10.3390/Pharmaceutics10040238 |
0.771 |
|
2018 |
Rzeczycki P, Woldemichael T, Willmer A, Murashov MD, Baik J, Keswani R, Yoon GS, Stringer KA, Rodriguez-Hornedo N, Rosania GR. An Expandable Mechanopharmaceutical Device (1): Measuring the Cargo Capacity of Macrophages in a Living Organism. Pharmaceutical Research. 36: 12. PMID 30421091 DOI: 10.1007/S11095-018-2539-6 |
0.776 |
|
2018 |
Rzeczycki P, Yoon GS, Keswani RK, Sud S, Baik J, Murashov MD, Bergin IL, Stringer KA, Rosania GR. An Expandable Mechanopharmaceutical Device (2): Drug Induced Granulomas Maximize the Cargo Sequestering Capacity of Macrophages in the Liver. Pharmaceutical Research. 36: 3. PMID 30406478 DOI: 10.1007/S11095-018-2541-Z |
0.767 |
|
2018 |
LaLone V, Mourão MA, Standiford TJ, Raghavendran K, Shedden K, Stringer KA, Rosania GR. An Expandable Mechanopharmaceutical Device (3): a Versatile Raman Spectral Cytometry Approach to Study the Drug Cargo Capacity of Individual Macrophages. Pharmaceutical Research. 36: 2. PMID 30402713 DOI: 10.1007/S11095-018-2540-0 |
0.81 |
|
2018 |
Woldemichael T, Keswani RK, Rzeczycki PM, Murashov MD, LaLone V, Gregorka B, Swanson JA, Stringer KA, Rosania GR. Reverse Engineering the Intracellular Self-Assembly of a Functional Mechanopharmaceutical Device. Scientific Reports. 8: 2934. PMID 29440773 DOI: 10.1038/S41598-018-21271-7 |
0.749 |
|
2017 |
Woldemichael T, Rosania GR. The physiological determinants of drug-induced lysosomal stress resistance. Plos One. 12: e0187627. PMID 29117253 DOI: 10.1371/Journal.Pone.0187627 |
0.757 |
|
2017 |
Murashov MD, LaLone V, Rzeczycki PM, Keswani RK, Yoon GS, Sud S, Rajeswaran W, Larsen S, Stringer KA, Rosania GR. The Physicochemical Basis of Clofazimine-Induced Skin Pigmentation. The Journal of Investigative Dermatology. PMID 29042210 DOI: 10.1016/J.Jid.2017.09.031 |
0.753 |
|
2017 |
Rzeczycki P, Yoon GS, Keswani RK, Sud S, Stringer KA, Rosania GR. Detecting ordered small molecule drug aggregates in live macrophages: a multi-parameter microscope image data acquisition and analysis strategy. Biomedical Optics Express. 8: 860-872. PMID 28270989 DOI: 10.1364/Boe.8.000860 |
0.805 |
|
2017 |
Horstman EM, Keswani RK, Frey BA, Rzeczycki PM, LaLone V, Bertke JA, Kenis PJ, Rosania GR. Elasticity in Macrophage-Synthesized Biocrystals. Angewandte Chemie (International Ed. in English). PMID 28079296 DOI: 10.1002/Anie.201611195 |
0.77 |
|
2016 |
Trexel J, Yoon GS, Keswani RK, McHugh C, Yeomans L, Vitvitsky V, Banerjee R, Sud S, Sun Y, Rosania GR, Stringer KA. Macrophage-Mediated Clofazimine Sequestration is Accompanied by a Shift in Host Energy Metabolism. Journal of Pharmaceutical Sciences. PMID 28007559 DOI: 10.1016/J.Xphs.2016.12.009 |
0.758 |
|
2016 |
Yoon GS, Keswani RK, Sud S, Rzeczycki PM, Murashov MD, Koehn TA, Standiford TJ, Stringer KA, Rosania GR. Clofazimine Biocrystal Accumulation in Macrophages Upregulates IL-1RA Production to Induce a Systemic Anti-Inflammatory State. Antimicrobial Agents and Chemotherapy. PMID 27021320 DOI: 10.1128/Aac.00265-16 |
0.753 |
|
2016 |
Keswani RK, Tian C, Peryea T, Girish G, Wang X, Rosania GR. Repositioning Clofazimine as a Macrophage-Targeting Photoacoustic Contrast Agent. Scientific Reports. 6: 23528. PMID 27000434 DOI: 10.1038/Srep23528 |
0.683 |
|
2016 |
Min KA, Rosania GR, Shin MC. Human Airway Primary Epithelial Cells Show Distinct Architectures on Membrane Supports Under Different Culture Conditions. Cell Biochemistry and Biophysics. PMID 26818810 DOI: 10.1007/S12013-016-0719-8 |
0.69 |
|
2016 |
Min KA, Rosania GR, Kim CK, Shin MC. Functional and cytometric examination of different human lung epithelial cell types as drug transport barriers. Archives of Pharmacal Research. PMID 26746641 DOI: 10.1007/S12272-015-0704-6 |
0.681 |
|
2016 |
Tian C, Keswani RK, Gandikota G, Rosania GR, Wang X. Contrast-enhanced photoacoustic tomography of human joints Proceedings of Spie. 9708. DOI: 10.1117/12.2213749 |
0.653 |
|
2015 |
Min KA, Rajeswaran WG, Oldenbourg R, Harris G, Keswani RK, Chiang M, Rzeczycki P, Talattof A, Hafeez M, Horobin RW, Larsen SD, Stringer KA, Rosania GR. Massive Bioaccumulation and Self-Assembly of Phenazine Compounds in Live Cells. Advanced Science. 2. PMID 26380168 DOI: 10.1002/Advs.201500025 |
0.773 |
|
2015 |
Lin S, Racz J, Tai MF, Brooks KM, Rzeczycki P, Heath LJ, Newstead MW, Standiford TJ, Rosania GR, Stringer KA. A Role for Low Density Lipoprotein Receptor-Related Protein 1 in the Cellular Uptake of Tissue Plasminogen Activator in the Lungs. Pharmaceutical Research. PMID 26231141 DOI: 10.1007/S11095-015-1763-6 |
0.743 |
|
2015 |
Keswani RK, Yoon GS, Sud S, Stringer KA, Rosania GR. A far-red fluorescent probe for flow cytometry and image-based functional studies of xenobiotic sequestering macrophages. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 87: 855-67. PMID 26109497 DOI: 10.1002/Cyto.A.22706 |
0.787 |
|
2015 |
Keswani RK, Baik J, Yeomans L, Hitzman C, Johnson AM, Pawate AS, Kenis PJ, Rodriguez-Hornedo N, Stringer KA, Rosania GR. Chemical Analysis of Drug Biocrystals: A Role for Counterion Transport Pathways in Intracellular Drug Disposition. Molecular Pharmaceutics. 12: 2528-36. PMID 25926092 DOI: 10.1021/Acs.Molpharmaceut.5B00032 |
0.775 |
|
2015 |
Yoon GS, Sud S, Keswani RK, Baik J, Standiford TJ, Stringer KA, Rosania GR. Phagocytosed Clofazimine Biocrystals Can Modulate Innate Immune Signaling by Inhibiting TNFα and Boosting IL-1RA Secretion. Molecular Pharmaceutics. 12: 2517-27. PMID 25909959 DOI: 10.1021/Acs.Molpharmaceut.5B00035 |
0.796 |
|
2015 |
Keswani RK, Yoon GS, Sud S, Stringer KA, Rosania GR. A far-red fluorescent probe for flow cytometry and image-based functional studies of xenobiotic sequestering macrophages Cytometry Part A. DOI: 10.1002/cyto.a.22706 |
0.766 |
|
2014 |
Min KA, Zhang X, Yu JY, Rosania GR. Computational approaches to analyse and predict small molecule transport and distribution at cellular and subcellular levels. Biopharmaceutics & Drug Disposition. 35: 15-32. PMID 24218242 DOI: 10.1002/Bdd.1879 |
0.743 |
|
2013 |
Baik J, Rosania GR. Modeling and Simulation of Intracellular Drug Transport and Disposition Pathways with Virtual Cell. Journal of Pharmaceutics & Pharmacology. 1. PMID 24364041 DOI: 10.13188/2327-204X.1000004 |
0.578 |
|
2013 |
Rosania GR, Shedden K, Zheng N, Zhang X. Visualizing chemical structure-subcellular localization relationships using fluorescent small molecules as probes of cellular transport. Journal of Cheminformatics. 5: 44. PMID 24093553 DOI: 10.1186/1758-2946-5-44 |
0.585 |
|
2013 |
Min KA, Talattof A, Tsume Y, Stringer KA, Yu JY, Lim DH, Rosania GR. The extracellular microenvironment explains variations in passive drug transport across different airway epithelial cell types. Pharmaceutical Research. 30: 2118-32. PMID 23708857 DOI: 10.1007/S11095-013-1069-5 |
0.727 |
|
2013 |
Min KA, Shin MC, Yu F, Yang M, David AE, Yang VC, Rosania GR. Pulsed magnetic field improves the transport of iron oxide nanoparticles through cell barriers Acs Nano. 7: 2161-2171. PMID 23373613 DOI: 10.1021/Nn3057565 |
0.624 |
|
2013 |
Baik J, Stringer KA, Mane G, Rosania GR. Multiscale distribution and bioaccumulation analysis of clofazimine reveals a massive immune system-mediated xenobiotic sequestration response Antimicrobial Agents and Chemotherapy. 57: 1218-1230. PMID 23263006 DOI: 10.1128/Aac.01731-12 |
0.611 |
|
2012 |
Baik J, Rosania GR. Macrophages Sequester Clofazimine in an Intracellular Liquid Crystal-Like Supramolecular Organization Plos One. 7. PMID 23071814 DOI: 10.1371/Journal.Pone.0047494 |
0.606 |
|
2012 |
Yu JY, Zheng N, Mane G, Min KA, Hinestroza JP, Zhu H, Stringer KA, Rosania GR. A cell-based computational modeling approach for developing site-directed molecular probes. Plos Computational Biology. 8: e1002378. PMID 22383866 DOI: 10.1371/Journal.Pcbi.1002378 |
0.743 |
|
2012 |
Suresh MV, Wagner MC, Rosania GR, Stringer KA, Min KA, Risler L, Shen DD, Georges GE, Reddy AT, Parkkinen J, Reddy RC. Pulmonary administration of a water-soluble curcumin complex reduces severity of acute lung injury American Journal of Respiratory Cell and Molecular Biology. 47: 280-287. PMID 22312018 DOI: 10.1165/Rcmb.2011-0175Oc |
0.637 |
|
2011 |
Zheng N, Tsai HN, Zhang X, Rosania GR. The subcellular distribution of small molecules: from pharmacokinetics to synthetic biology. Molecular Pharmaceutics. 8: 1619-28. PMID 21805990 DOI: 10.1021/Mp200092V |
0.619 |
|
2011 |
Baik J, Rosania GR. Molecular imaging of intracellular drug-membrane aggregate formation Molecular Pharmaceutics. 8: 1742-1749. PMID 21800872 DOI: 10.1021/Mp200101B |
0.661 |
|
2011 |
Zheng N, Tsai HN, Zhang X, Shedden K, Rosania GR. The subcellular distribution of small molecules: a meta-analysis. Molecular Pharmaceutics. 8: 1611-8. PMID 21774504 DOI: 10.1021/Mp200093Z |
0.593 |
|
2011 |
Zheng N, Zhang X, Rosania GR. Effect of phospholipidosis on the cellular pharmacokinetics of chloroquine. The Journal of Pharmacology and Experimental Therapeutics. 336: 661-71. PMID 21156819 DOI: 10.1124/Jpet.110.175679 |
0.627 |
|
2010 |
Min KA, Yu F, Yang VC, Zhang X, Rosania GR. Transcellular Transport of Heparin-coated Magnetic Iron Oxide Nanoparticles (Hep-MION) Under the Influence of an Applied Magnetic Field. Pharmaceutics. 2: 119-135. PMID 21152371 DOI: 10.3390/Pharmaceutics2020119 |
0.67 |
|
2010 |
Shedden K, Rosania GR. Chemical address tags of fluorescent bioimaging probes. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 77: 429-38. PMID 20104576 DOI: 10.1002/Cyto.A.20847 |
0.304 |
|
2010 |
Yu JY, Rosania GR. Cell-based multiscale computational modeling of small molecule absorption and retention in the lungs. Pharmaceutical Research. 27: 457-67. PMID 20099073 DOI: 10.1007/S11095-009-0034-9 |
0.538 |
|
2010 |
Zhang X, Zheng N, Zou P, Zhu H, Hinestroza JP, Rosania GR. Cells on pores: A simulation-driven analysis of transcellular small molecule transport Molecular Pharmaceutics. 7: 456-467. PMID 20025248 DOI: 10.1021/Mp9001969 |
0.584 |
|
2010 |
Min KA, Yu F, Yang VC, Zhang X, Rosania GR. Transcellular transport of heparin-coated magnetic iron oxide nanoparticles (Hep-MION) under the influence of an applied magnetic field Pharmaceutics. 2: 119-135. DOI: 10.3390/pharmaceutics2020119 |
0.624 |
|
2009 |
Shedden K, Li Q, Liu F, Chang YT, Rosania GR. Machine vision-assisted analysis of structure-localization relationships in a combinatorial library of prospective bioimaging probes. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 75: 482-93. PMID 19243023 DOI: 10.1002/Cyto.A.20713 |
0.512 |
|
2009 |
Abdullah NM, Rosania GR, Shedden K. Selective targeting of tumorigenic cancer cell lines by microtubule inhibitors. Plos One. 4: e4470. PMID 19214225 DOI: 10.1371/Journal.Pone.0004470 |
0.334 |
|
2008 |
Trapp S, Rosania GR, Horobin RW, Kornhuber J. Quantitative modeling of selective lysosomal targeting for drug design European Biophysics Journal. 37: 1317-1328. PMID 18504571 DOI: 10.1007/S00249-008-0338-4 |
0.378 |
|
2008 |
Zhang X, Zheng N, Rosania GR. Simulation-based cheminformatic analysis of organelle-targeted molecules: Lysosomotropic monobasic amines Journal of Computer-Aided Molecular Design. 22: 629-645. PMID 18338229 DOI: 10.1007/S10822-008-9194-7 |
0.618 |
|
2007 |
Shedden K, Posada MM, Chang YT, Li Q, Rosania G. Prospecting for Live Cell BioImaging Probes With Cheminformatic Assisted Image Arrays (CAIA). Proceedings / Ieee International Symposium On Biomedical Imaging: From Nano to Macro. Ieee International Symposium On Biomedical Imaging. 1108-1111. PMID 23482717 DOI: 10.1109/ISBI.2007.357050 |
0.444 |
|
2007 |
Chen VY, Posada MM, Zhao L, Rosania GR. Rapid doxorubicin efflux from the nucleus of drug-resistant cancer cells following extracellular drug clearance Pharmaceutical Research. 24: 2156-2167. PMID 17668300 DOI: 10.1007/S11095-007-9369-2 |
0.682 |
|
2006 |
Chen VY, Rosania GR. The great multidrug-resistance paradox. Acs Chemical Biology. 1: 271-273. PMID 17163753 DOI: 10.1021/Cb600215Q |
0.691 |
|
2006 |
Zhang X, Shedden K, Rosania GR. A cell-based molecular transport simulator for pharmacokinetic prediction and cheminformatic exploration. Molecular Pharmaceutics. 3: 704-16. PMID 17140258 DOI: 10.1021/Mp060046K |
0.545 |
|
2006 |
Chen VY, Posada MM, Blazer LL, Zhao T, Rosania GR. The role of the VPS4a-exosome pathway in the intrinsic egress route of a DNA-binding anticancer drug Pharmaceutical Research. 23: 1687-1695. PMID 16841193 DOI: 10.1007/S11095-006-9043-0 |
0.698 |
|
2006 |
Li Q, Kim Y, Namm J, Kulkarni A, Rosania GR, Ahn YH, Chang YT. RNA-selective, live cell imaging probes for studying nuclear structure and function. Chemistry & Biology. 13: 615-23. PMID 16793519 DOI: 10.1016/J.Chembiol.2006.04.007 |
0.49 |
|
2004 |
Chen VY, Khersonsky SM, Shedden K, Chang YT, Rosania GR. System dynamics of subcellular transport. Molecular Pharmaceutics. 1: 414-25. PMID 16028353 DOI: 10.1021/Mp049916T |
0.712 |
|
2004 |
Shedden K, Rosania GR. Exploratory chemoinformatic analysis of cell type-selective anticancer drug targeting. Molecular Pharmaceutics. 1: 267-80. PMID 15981586 DOI: 10.1021/Mp049953K |
0.365 |
|
2004 |
Kim S, Rosania GR, Chang YT. Dedifferentiation? What's next? Molecular Interventions. 4: 83-85. PMID 15087481 DOI: 10.1124/Mi.4.2.5 |
0.41 |
|
2003 |
Shedden K, Brumer J, Chang YT, Rosania GR. Chemoinformatic analysis of a supertargeted combinatorial library of styryl molecules. Journal of Chemical Information and Computer Sciences. 43: 2068-80. PMID 14632459 DOI: 10.1021/Ci0341215 |
0.457 |
|
2003 |
Lee JW, Jung M, Rosania GR, Chang YT. Development of novel cell-permeable DNA sensitive dyes using combinatorial synthesis and cell-based screening. Chemical Communications (Cambridge, England). 1852-3. PMID 12931999 DOI: 10.1039/B303960A |
0.501 |
|
2003 |
Shedden K, Xie XT, Chandaroy P, Chang YT, Rosania GR. Expulsion of small molecules in vesicles shed by cancer cells: association with gene expression and chemosensitivity profiles. Cancer Research. 63: 4331-7. PMID 12907600 |
0.747 |
|
2003 |
Rosania GR, Lee JW, Ding L, Yoon HS, Chang YT. Combinatorial approach to organelle-targeted fluorescent library based on the styryl scaffold Journal of the American Chemical Society. 125: 1130-1131. PMID 12553790 DOI: 10.1021/Ja027587X |
0.489 |
|
2002 |
Moon HS, Jacobson EM, Khersonsky SM, Luzung MR, Walsh DP, Xiong W, Lee JW, Parikh PB, Lam JC, Kang TW, Rosania GR, Schier AF, Chang YT. A novel microtubule destabilizing entity from orthogonal synthesis of triazine library and zebrafish embryo screening. Journal of the American Chemical Society. 124: 11608-9. PMID 12296721 DOI: 10.1021/Ja026720I |
0.462 |
|
2002 |
Perez OD, Chang YT, Rosania G, Sutherlin D, Schultz PG. Inhibition and reversal of myogenic differentiation by purine-based microtubule assembly inhibitors. Chemistry & Biology. 9: 475-83. PMID 11983336 DOI: 10.1016/S1074-5521(02)00131-X |
0.728 |
|
2001 |
Chang YT, Wignall SM, Rosania GR, Gray NS, Hanson SR, Su AI, Merlie J, Moon HS, Sangankar SB, Perez O, Heald R, Schultz PG. Synthesis and biological evaluation of myoseverin derivatives: microtubule assembly inhibitors. Journal of Medicinal Chemistry. 44: 4497-500. PMID 11741468 DOI: 10.1021/Jm010451+ |
0.78 |
|
2001 |
Chang YT, Rosania GR, Chung SK. Inositol phospholipid pathway inhibitors and regulators Expert Opinion On Therapeutic Patents. 11: 45-59. DOI: 10.1517/13543776.11.1.45 |
0.433 |
|
2000 |
Rosania GR, Chang YT, Perez O, Sutherlin D, Dong H, Lockhart DJ, Schultz PG. Myoseverin, a microtubule-binding molecule with novel cellular effects. Nature Biotechnology. 18: 304-8. PMID 10700146 DOI: 10.1038/73753 |
0.734 |
|
1999 |
Chang YT, Gray NS, Rosania GR, Sutherlin DP, Kwon S, Norman TC, Sarohia R, Leost M, Meijer L, Schultz PG. Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors. Chemistry & Biology. 6: 361-75. PMID 10375538 DOI: 10.1016/S1074-5521(99)80048-9 |
0.781 |
|
1999 |
Rosania GR, Merlie J, Gray N, Chang YT, Schultz PG, Heald R. A cyclin-dependent kinase inhibitor inducing cancer cell differentiation: biochemical identification using Xenopus egg extracts. Proceedings of the National Academy of Sciences of the United States of America. 96: 4797-802. PMID 10220373 DOI: 10.1073/Pnas.96.9.4797 |
0.524 |
|
1996 |
Rosania GR, Swanson JA. Microtubules can modulate pseudopod activity from a distance inside macrophages Cell Motility and the Cytoskeleton. 34: 230-245. PMID 8816289 DOI: 10.1002/(Sici)1097-0169(1996)34:3<230::Aid-Cm6>3.0.Co;2-D |
0.502 |
|
1995 |
Rosania GR, Swanson JA. Effects of Macromolecular Crowding on Nuclear Size Experimental Cell Research. 218: 114-122. PMID 7537686 DOI: 10.1006/Excr.1995.1137 |
0.44 |
|
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