Daniel C. Gray, Ph.D.
Affiliations: | Chemistry and Chemical Biology | University of California, San Francisco, San Francisco, CA |
Area:
molecular recognitionGoogle:
"Daniel Gray"Mean distance: 9.91 | S | N | B | C | P |
Parents
Sign in to add mentor| James A. Wells | grad student | 2011 | UCSF | |
| (Activation of specific apoptotic caspases with an engineered small-molecule-activated protease.) | ||||
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Publications
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| Shigdel UK, Lee SJ, Sowa ME, et al. (2020) Genomic discovery of an evolutionarily programmed modality for small-molecule targeting of an intractable protein surface. Proceedings of the National Academy of Sciences of the United States of America |
| Morgan CW, Diaz JE, Zeitlin SG, et al. (2015) Engineered cellular gene-replacement platform for selective and inducible proteolytic profiling. Proceedings of the National Academy of Sciences of the United States of America |
| Yang CF, Chiang MC, Gray DC, et al. (2013) Sexually dimorphic neurons in the ventromedial hypothalamus govern mating in both sexes and aggression in males. Cell. 153: 896-909 |
| Staben ST, Ndubaku C, Blaquiere N, et al. (2013) Discovery of thiazolobenzoxepin PI3-kinase inhibitors that spare the PI3-kinase β isoform. Bioorganic & Medicinal Chemistry Letters. 23: 2606-13 |
| Gray DC, Mahrus S, Wells JA. (2010) Activation of specific apoptotic caspases with an engineered small-molecule-activated protease. Cell. 142: 637-46 |
| Wells JA, Wolan D, Zorn J, et al. (2010) Abstract SY11-03: Turning enzymes on with small molecules Cancer Research. 70 |
| Wolan DW, Zorn JA, Gray DC, et al. (2009) Small-molecule activators of a proenzyme. Science (New York, N.Y.). 326: 853-8 |
| Jost PJ, Grabow S, Gray D, et al. (2009) XIAP discriminates between type I and type II FAS-induced apoptosis. Nature. 460: 1035-9 |
| Okuzumi T, Fiedler D, Zhang C, et al. (2009) Inhibitor hijacking of Akt activation. Nature Chemical Biology. 5: 484-93 |
| Degtyarev M, De Mazière A, Orr C, et al. (2008) Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents. The Journal of Cell Biology. 183: 101-16 |