| Year |
Citation |
Score |
| 2020 |
Shigdel UK, Lee SJ, Sowa ME, Bowman BR, Robison K, Zhou M, Pua KH, Stiles DT, Blodgett JAV, Udwary DW, Rajczewski AT, Mann AS, Mostafavi S, Hardy T, Arya S, ... ... Gray DC, et al. Genomic discovery of an evolutionarily programmed modality for small-molecule targeting of an intractable protein surface. Proceedings of the National Academy of Sciences of the United States of America. PMID 32606248 DOI: 10.1073/Pnas.2006560117 |
0.365 |
|
| 2015 |
Morgan CW, Diaz JE, Zeitlin SG, Gray DC, Wells JA. Engineered cellular gene-replacement platform for selective and inducible proteolytic profiling. Proceedings of the National Academy of Sciences of the United States of America. PMID 26106156 DOI: 10.1073/Pnas.1504141112 |
0.667 |
|
| 2013 |
Yang CF, Chiang MC, Gray DC, Prabhakaran M, Alvarado M, Juntti SA, Unger EK, Wells JA, Shah NM. Sexually dimorphic neurons in the ventromedial hypothalamus govern mating in both sexes and aggression in males. Cell. 153: 896-909. PMID 23663785 DOI: 10.1016/J.Cell.2013.04.017 |
0.406 |
|
| 2013 |
Staben ST, Ndubaku C, Blaquiere N, Belvin M, Bull RJ, Dudley D, Edgar K, Gray D, Heald R, Heffron TP, Jones GE, Jones M, Kolesnikov A, Lee L, Lesnick J, et al. Discovery of thiazolobenzoxepin PI3-kinase inhibitors that spare the PI3-kinase β isoform. Bioorganic & Medicinal Chemistry Letters. 23: 2606-13. PMID 23540645 DOI: 10.1016/J.Bmcl.2013.02.102 |
0.388 |
|
| 2010 |
Gray DC, Mahrus S, Wells JA. Activation of specific apoptotic caspases with an engineered small-molecule-activated protease. Cell. 142: 637-46. PMID 20723762 DOI: 10.1016/J.Cell.2010.07.014 |
0.668 |
|
| 2010 |
Wells JA, Wolan D, Zorn J, Datta D, Gray D, Sadowsky J. Abstract SY11-03: Turning enzymes on with small molecules Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Sy11-03 |
0.585 |
|
| 2009 |
Wolan DW, Zorn JA, Gray DC, Wells JA. Small-molecule activators of a proenzyme. Science (New York, N.Y.). 326: 853-8. PMID 19892984 DOI: 10.1126/Science.1177585 |
0.638 |
|
| 2009 |
Jost PJ, Grabow S, Gray D, McKenzie MD, Nachbur U, Huang DC, Bouillet P, Thomas HE, Borner C, Silke J, Strasser A, Kaufmann T. XIAP discriminates between type I and type II FAS-induced apoptosis. Nature. 460: 1035-9. PMID 19626005 DOI: 10.1038/nature08229 |
0.379 |
|
| 2009 |
Okuzumi T, Fiedler D, Zhang C, Gray DC, Aizenstein B, Hoffman R, Shokat KM. Inhibitor hijacking of Akt activation. Nature Chemical Biology. 5: 484-93. PMID 19465931 DOI: 10.1038/Nchembio.183 |
0.395 |
|
| 2008 |
Degtyarev M, De Mazière A, Orr C, Lin J, Lee BB, Tien JY, Prior WW, van Dijk S, Wu H, Gray DC, Davis DP, Stern HM, Murray LJ, Hoeflich KP, Klumperman J, et al. Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents. The Journal of Cell Biology. 183: 101-16. PMID 18838554 DOI: 10.1083/Jcb.200801099 |
0.43 |
|
| 2006 |
Hoeflich KP, Eby MT, Forrest WF, Gray DC, Tien JY, Stern HM, Murray LJ, Davis DP, Modrusan Z, Seshagiri S. Regulation of ERK3/MAPK6 expression by BRAF. International Journal of Oncology. 29: 839-49. PMID 16964379 DOI: 10.3892/Ijo.29.4.839 |
0.45 |
|
| 2006 |
Hoeflich KP, Gray DC, Eby MT, Tien JY, Wong L, Bower J, Gogineni A, Zha J, Cole MJ, Stern HM, Murray LJ, Davis DP, Seshagiri S. Oncogenic BRAF is required for tumor growth and maintenance in melanoma models. Cancer Research. 66: 999-1006. PMID 16424035 DOI: 10.1158/0008-5472.Can-05-2720 |
0.368 |
|
| 2005 |
Gray D, Jubb AM, Hogue D, Dowd P, Kljavin N, Yi S, Bai W, Frantz G, Zhang Z, Koeppen H, de Sauvage FJ, Davis DP. Maternal embryonic leucine zipper kinase/murine protein serine-threonine kinase 38 is a promising therapeutic target for multiple cancers. Cancer Research. 65: 9751-61. PMID 16266996 DOI: 10.1158/0008-5472.Can-04-4531 |
0.31 |
|
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