☰

Scott B. Hansen, Ph.D. - Publications

Affiliations: 
Scripps Institute, Florida  
Area:
Biochemistry
Website:
https://www.scripps.edu/faculty/hansen/
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25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Pavel MA, Petersen EN, Wang H, Lerner RA, Hansen SB. Studies on the mechanism of general anesthesia. Proceedings of the National Academy of Sciences of the United States of America. PMID 32467161 DOI: 10.1073/Pnas.2004259117  0.361
2019 Petersen EN, Pavel MA, Wang H, Hansen SB. Disruption of palmitate-mediated localization; a shared pathway of force and anesthetic activation of TREK-1 channels. Biochimica Et Biophysica Acta. Biomembranes. 183091. PMID 31672538 DOI: 10.1016/J.Bbamem.2019.183091  0.384
2019 Robinson CV, Rohacs T, Hansen SB. Tools for Understanding Nanoscale Lipid Regulation of Ion Channels. Trends in Biochemical Sciences. PMID 31060927 DOI: 10.1016/J.Tibs.2019.04.001  0.354
2018 Chung HW, Nicholas Petersen E, Cabanos C, Murphy KR, Pavel MA, Hansen AS, Ja WW, Hansen SB. A Molecular Target for an Alcohol Chain Length Cutoff. Journal of Molecular Biology. PMID 30529033 DOI: 10.1016/J.Jmb.2018.11.028  0.721
2017 Cabanos C, Wang M, Han X, Hansen SB. A Soluble Fluorescent Binding Assay Reveals PIP2 Antagonism of TREK-1 Channels. Cell Reports. 20: 1287-1294. PMID 28793254 DOI: 10.1016/J.Celrep.2017.07.034  0.741
2015 Hansen SB. Lipid agonism: The PIP2 paradigm of ligand-gated ion channels. Biochimica Et Biophysica Acta. 1851: 620-628. PMID 25633344 DOI: 10.1016/J.Bbalip.2015.01.011  0.401
2011 Hansen SB, Tao X, MacKinnon R. Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2. Nature. 477: 495-8. PMID 21874019 DOI: 10.1038/Nature10370  0.486
2010 Sine SM, Wang HL, Hansen S, Taylor P. On the origin of ion selectivity in the Cys-loop receptor family. Journal of Molecular Neuroscience : Mn. 40: 70-6. PMID 19728176 DOI: 10.1007/S12031-009-9260-1  0.71
2008 Hansen SB, Wang HL, Taylor P, Sine SM. An ion selectivity filter in the extracellular domain of Cys-loop receptors reveals determinants for ion conductance. The Journal of Biological Chemistry. 283: 36066-70. PMID 18940802 DOI: 10.1074/Jbc.C800194200  0.703
2007 Taylor P, Talley TT, Radic' Z, Hansen SB, Hibbs RE, Shi J. Structure-guided drug design: conferring selectivity among neuronal nicotinic receptor and acetylcholine-binding protein subtypes. Biochemical Pharmacology. 74: 1164-71. PMID 17826748 DOI: 10.1016/J.Bcp.2007.07.038  0.795
2007 Hansen SB, Taylor P. Galanthamine and non-competitive inhibitor binding to ACh-binding protein: evidence for a binding site on non-alpha-subunit interfaces of heteromeric neuronal nicotinic receptors. Journal of Molecular Biology. 369: 895-901. PMID 17481657 DOI: 10.1016/J.Jmb.2007.03.067  0.691
2006 Bourne Y, Hansen SB, Sulzenbacher G, Talley TT, Huxford T, Taylor P, Marchot P. Structural comparison of three crystalline complexes of a peptidic toxin with a synaptic acetylcholine recognition protein. Journal of Molecular Neuroscience : Mn. 30: 103-4. PMID 17192648 DOI: 10.1385/Jmn:30:1:103  0.745
2006 Hansen SB, Sulzenbacher G, Huxford T, Marchot P, Bourne Y, Taylor P. Structural characterization of agonist and antagonist-bound acetylcholine-binding protein from Aplysia californica. Journal of Molecular Neuroscience : Mn. 30: 101-2. PMID 17192647 DOI: 10.1385/Jmn:30:1:101  0.695
2006 Gao F, Mer G, Tonelli M, Hansen SB, Burghardt TP, Taylor P, Sine SM. Solution NMR of acetylcholine binding protein reveals agonist-mediated conformational change of the C-loop. Molecular Pharmacology. 70: 1230-5. PMID 16847142 DOI: 10.1124/Mol.106.027185  0.711
2006 Radić Z, Talley TT, Hansen SB, Yu W, Taylor P. Interaction of organophosphate and carbamate cholinesterase inhibitors with acetylcholine binding proteins Toxicology Letters. 164: S239. DOI: 10.1016/J.Toxlet.2006.07.157  0.742
2005 Hibbs RE, Johnson DA, Shi J, Hansen SB, Taylor P. Structural dynamics of the alpha-neurotoxin-acetylcholine-binding protein complex: hydrodynamic and fluorescence anisotropy decay analyses. Biochemistry. 44: 16602-11. PMID 16342951 DOI: 10.1021/Bi051735P  0.736
2005 Hansen SB, Sulzenbacher G, Huxford T, Marchot P, Taylor P, Bourne Y. Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations. The Embo Journal. 24: 3635-46. PMID 16193063 DOI: 10.1038/Sj.Emboj.7600828  0.71
2005 Bourne Y, Talley TT, Hansen SB, Taylor P, Marchot P. Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake alpha-neurotoxins and nicotinic receptors. The Embo Journal. 24: 1512-22. PMID 15791209 DOI: 10.1038/Sj.Emboj.7600620  0.786
2005 Gao F, Bren N, Burghardt TP, Hansen S, Henchman RH, Taylor P, McCammon JA, Sine SM. Agonist-mediated conformational changes in acetylcholine-binding protein revealed by simulation and intrinsic tryptophan fluorescence. The Journal of Biological Chemistry. 280: 8443-51. PMID 15591050 DOI: 10.1074/Jbc.M412389200  0.739
2004 Bouzat C, Gumilar F, Spitzmaul G, Wang HL, Rayes D, Hansen SB, Taylor P, Sine SM. Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel. Nature. 430: 896-900. PMID 15318223 DOI: 10.1038/Nature02753  0.752
2004 Hansen SB, Talley TT, Radic Z, Taylor P. Structural and ligand recognition characteristics of an acetylcholine-binding protein from Aplysia californica. The Journal of Biological Chemistry. 279: 24197-202. PMID 15069068 DOI: 10.1074/Jbc.M402452200  0.781
2004 Taylor P, Hansen SB, Talley TT, Hibbs RE, Radi? Z. Contemporary paradigms for cholinergic ligand design guided by biological structure. Bioorganic & Medicinal Chemistry Letters. 14: 1875-7. PMID 15050619 DOI: 10.1016/J.Bmcl.2003.10.072  0.773
2003 Gao F, Bern N, Little A, Wang HL, Hansen SB, Talley TT, Taylor P, Sine SM. Curariform antagonists bind in different orientations to acetylcholine-binding protein. The Journal of Biological Chemistry. 278: 23020-6. PMID 12682067 DOI: 10.1074/Jbc.M301151200  0.801
2002 Hansen SB, Radic' Z, Talley TT, Molles BE, Deerinck T, Tsigelny I, Taylor P. Tryptophan fluorescence reveals conformational changes in the acetylcholine binding protein. The Journal of Biological Chemistry. 277: 41299-302. PMID 12235129 DOI: 10.1074/Jbc.C200462200  0.801
2000 Ishizu K, Smith DF, Bender D, Danielsen E, Hansen SB, Wong DF, Cumming P, Gjedde A. Positron emission tomography of radioligand binding in porcine striatum in vivo: haloperidol inhibition linked to endogenous ligand release. Synapse (New York, N.Y.). 38: 87-101. PMID 10941144 DOI: 10.1002/1098-2396(200010)38:1<87::Aid-Syn10>3.0.Co;2-C  0.343
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