Eric D. Merkley, Ph.D. - Publications

Affiliations: 
2010 University of Washington, Seattle, Seattle, WA 
Area:
biophysics, protein dynamics, molecular dynamics simulations, amyloid

25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Zhou M, Laureanti JA, Bell CJ, Kwon M, Meng Q, Novikova IV, Thomas DG, Nicora CD, Sontag RL, Bedgar DL, O'Bryon I, Merkley ED, Ginovska B, Cort JR, Davin LB, et al. sequencing and native mass spectrometry revealed hetero-association of dirigent protein homologs and potential interacting proteins in × . The Analyst. PMID 34806721 DOI: 10.1039/d1an01476e  0.452
2020 O'Bryon I, Jenson SC, Merkley ED. Flying Blind, or Just Flying Under the Radar? The Underappreciated Power of de novo Methods of Mass Spectrometric Peptide Identification. Protein Science : a Publication of the Protein Society. PMID 32713088 DOI: 10.1002/Pro.3919  0.364
2019 Merkley ED, Burnum-Johnson KE, Anderson LN, Jenson SC, Wahl KL. Uniformly N-Labeled Recombinant Ricin A-chain as an Internal Retention Time Standard for Increased Confidence in Forensic Identification of Ricin by Untargeted Nanoflow Liquid Chromatography-Tandem Mass Spectrometry. Analytical Chemistry. PMID 31596564 DOI: 10.1021/Acs.Analchem.9B03389  0.303
2019 O'Bryon I, Tucker AE, Kaiser BLD, Wahl KL, Merkley ED. Constructing a Tandem Mass Spectral Library for Forensic Ricin Identification. Journal of Proteome Research. PMID 31566388 DOI: 10.1021/Acs.Jproteome.9B00377  0.379
2019 Heller NC, Garrett AM, Merkley ED, Cendrowski SR, Melville AM, Arce JS, Jenson SC, Wahl KL, Jarman KH. The probabilistic limit of detection for ricin identification using a shotgun proteomics assay. Analytical Chemistry. PMID 31490662 DOI: 10.1021/Acs.Analchem.9B02721  0.34
2019 Caswell J, Gans JD, Generous N, Hudson CM, Merkley E, Johnson C, Oehmen C, Omberg K, Purvine E, Taylor K, Ting CL, Wolinsky M, Xie G. Defending Our Public Biological Databases as a Global Critical Infrastructure. Frontiers in Bioengineering and Biotechnology. 7: 58. PMID 31024904 DOI: 10.3389/Fbioe.2019.00058  0.346
2019 Merkley ED, Wunschel DS, Wahl KL, Jarman KH. Applications and challenges of forensic proteomics. Forensic Science International. 297: 350-363. PMID 30929674 DOI: 10.1016/J.Forsciint.2019.01.022  0.428
2018 Jarman KH, Heller NC, Jenson SC, Hutchinson JR, Kaiser BLD, Payne SH, Wunschel DS, Merkley ED. Proteomics goes to court: A statistical foundation for forensic toxin/organism identification using bottom-up proteomics. Journal of Proteome Research. PMID 30109807 DOI: 10.1021/Acs.Jproteome.8B00212  0.359
2017 Wunschel DS, Hutchison JR, Deatherage Kaiser BL, Merkley ED, Hess BM, Lin A, Warner MG. Proteomic signatures differentiating Bacillus anthracis Sterne sporulation on soil relative to laboratory media. The Analyst. PMID 29165439 DOI: 10.1039/C7An01412K  0.44
2017 Merkley ED, Jenson SC, Arce JS, Melville AM, Leiser OP, Wunschel DS, Wahl KL. Ricin-like proteins from the castor plant do not influence liquid chromatography-mass spectrometry detection of ricin in forensically relevant samples. Toxicon : Official Journal of the International Society On Toxinology. PMID 29031940 DOI: 10.1016/J.Toxicon.2017.10.004  0.419
2017 Merkley ED, Sego LH, Lin A, Leiser OP, Kaiser BLD, Adkins JN, Keim PS, Wagner DM, Kreuzer HW. Protein abundances can distinguish between naturally-occurring and laboratory strains of Yersinia pestis, the causative agent of plague. Plos One. 12: e0183478. PMID 28854255 DOI: 10.1371/Journal.Pone.0183478  0.455
2015 Leiser OP, Merkley ED, Clowers BH, Deatherage Kaiser BL, Lin A, Hutchison JR, Melville AM, Wagner DM, Keim PS, Foster JT, Kreuzer HW. Investigation of Yersinia pestis Laboratory Adaptation through a Combined Genomics and Proteomics Approach. Plos One. 10: e0142997. PMID 26599979 DOI: 10.1371/Journal.Pone.0142997  0.325
2015 Lin A, Merkley ED, Clowers BH, Hutchison JR, Kreuzer HW. Effects of bacterial inactivation methods on downstream proteomic analysis. Journal of Microbiological Methods. 112: 3-10. PMID 25620019 DOI: 10.1016/J.Mimet.2015.01.015  0.319
2015 Merkley ED, Wrighton KC, Castelle CJ, Anderson BJ, Wilkins MJ, Shah V, Arbour T, Brown JN, Singer SW, Smith RD, Lipton MS. Changes in protein expression across laboratory and field experiments in Geobacter bemidjiensis. Journal of Proteome Research. 14: 1361-75. PMID 25496566 DOI: 10.1021/Pr500983V  0.377
2014 Merkley ED, Rysavy S, Kahraman A, Hafen RP, Daggett V, Adkins JN. Distance restraints from crosslinking mass spectrometry: mining a molecular dynamics simulation database to evaluate lysine-lysine distances. Protein Science : a Publication of the Protein Society. 23: 747-59. PMID 24639379 DOI: 10.1002/Pro.2458  0.644
2014 Sadler NC, Melnicki MR, Serres MH, Merkley ED, Chrisler WB, Hill EA, Romine MF, Kim S, Zink EM, Datta S, Smith RD, Beliaev AS, Konopka A, Wright AT. Live cell chemical profiling of temporal redox dynamics in a photoautotrophic cyanobacterium. Acs Chemical Biology. 9: 291-300. PMID 24168666 DOI: 10.1021/Cb400769V  0.515
2014 Merkley ED, Metz TO, Smith RD, Baynes JW, Frizzell N. The succinated proteome. Mass Spectrometry Reviews. 33: 98-109. PMID 24115015 DOI: 10.1002/Mas.21382  0.398
2013 Merkley ED, Cort JR, Adkins JN. Cross-linking and mass spectrometry methodologies to facilitate structural biology: finding a path through the maze. Journal of Structural and Functional Genomics. 14: 77-90. PMID 23917845 DOI: 10.1007/S10969-013-9160-Z  0.403
2013 Merkley ED, Baker ES, Crowell KL, Orton DJ, Taverner T, Ansong C, Ibrahim YM, Burnet MC, Cort JR, Anderson GA, Smith RD, Adkins JN. Mixed-isotope labeling with LC-IMS-MS for characterization of protein-protein interactions by chemical cross-linking. Journal of the American Society For Mass Spectrometry. 24: 444-9. PMID 23423792 DOI: 10.1007/S13361-012-0565-X  0.375
2012 Merkley ED, Anderson BJ, Park J, Belchik SM, Shi L, Monroe ME, Smith RD, Lipton MS. Detection and identification of heme c-modified peptides by histidine affinity chromatography, high-performance liquid chromatography-mass spectrometry, and database searching. Journal of Proteome Research. 11: 6147-58. PMID 23082897 DOI: 10.1021/Pr3007914  0.319
2012 Merkley ED, Daggett V, Parson WW. A temperature-dependent conformational change of NADH oxidase from Thermus thermophilus HB8. Proteins. 80: 546-55. PMID 22081476 DOI: 10.1002/Prot.23219  0.661
2011 Zhang H, Yang F, Qian WJ, Brown RN, Wang Y, Merkley ED, Merkley EE, Park JH, Monroe ME, Purvine SO, Moore RJ, Shi L, Fredrickson JK, PaÅ¡a-Tolić L, Smith RD, et al. Identification of c-type heme-containing peptides using nonactivated immobilized metal affinity chromatography resin enrichment and higher-energy collisional dissociation. Analytical Chemistry. 83: 7260-8. PMID 21740036 DOI: 10.1021/Ac2000829  0.374
2010 van der Kamp MW, Schaeffer RD, Jonsson AL, Scouras AD, Simms AM, Toofanny RD, Benson NC, Anderson PC, Merkley ED, Rysavy S, Bromley D, Beck DA, Daggett V. Dynameomics: a comprehensive database of protein dynamics. Structure (London, England : 1993). 18: 423-35. PMID 20399180 DOI: 10.1016/J.Str.2010.01.012  0.339
2010 Merkley ED, Parson WW, Daggett V. Temperature dependence of the flexibility of thermophilic and mesophilic flavoenzymes of the nitroreductase fold. Protein Engineering, Design & Selection : Peds. 23: 327-36. PMID 20083491 DOI: 10.1093/Protein/Gzp090  0.731
2008 Merkley ED, Bernard B, Daggett V. Conformational changes below the Tm: molecular dynamics studies of the thermal pretransition of ribonuclease A. Biochemistry. 47: 880-92. PMID 18161991 DOI: 10.1021/Bi701565B  0.611
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