Joseph C. Wu, Ph.D. - Publications

Affiliations: 
2004 University of California, Los Angeles, Los Angeles, CA 
Area:
molecular imaging

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Year Citation  Score
2024 Thomas D, Noishiki C, Gaddam S, Wu D, Manhas A, Liu Y, Tripathi D, Kathale N, Adkar SS, Garhyan J, Liu C, Xu B, Ross EG, Dalman RL, Wang KC, ... ... Wu JC, et al. CCL2-mediated endothelial injury drives cardiac dysfunction in long COVID. Nature Cardiovascular Research. 3: 1249-1265. PMID 39402206 DOI: 10.1038/s44161-024-00543-8  0.787
2024 Yang Y, Valencia LA, Lu CH, Nakamoto ML, Tsai CT, Liu C, Yang H, Zhang W, Jahed Z, Lee WR, Santoro F, Liou J, Wu JC, Cui B. Plasma membrane curvature regulates the formation of contacts with the endoplasmic reticulum. Nature Cell Biology. PMID 39289582 DOI: 10.1038/s41556-024-01511-x  0.629
2024 Wu Y, Sun T, Medina P, Narasimhan P, Stevenson DK, Von Versen-Höynck F, Armstrong J, Wu JC, Sayed N, Winn VD. A Novel Stem Cell Model to Study Preeclampsia Endothelial Dysfunction. Reproductive Sciences (Thousand Oaks, Calif.). PMID 39179924 DOI: 10.1007/s43032-024-01590-z  0.612
2024 Dexheimer R, Manhas A, Wu D, Tripathi D, Yu Chan S, Li J, Yu R, Sayed N, Wu JC, Sallam K. Generation of two iPSC lines from dilated cardiomyopathy patients with pathogenic variants in the SCN5A gene. Stem Cell Research. 80: 103498. PMID 39067410 DOI: 10.1016/j.scr.2024.103498  0.787
2024 Yang Y, Valencia LA, Lu CH, Nakamoto ML, Tsai CT, Liu C, Yang H, Zhang W, Jahed Z, Lee WR, Santoro F, Liou J, Wu JC, Cui B. Membrane Curvature Promotes ER-PM Contact Formation via Junctophilin-EHD Interactions. Biorxiv : the Preprint Server For Biology. PMID 38979311 DOI: 10.1101/2024.06.29.601287  0.629
2024 Juguilon C, Wu JC. The role of the International Society for Stem Cell Research (ISSCR) guidelines in disease modeling. Disease Models & Mechanisms. 17. PMID 38973350 DOI: 10.1242/dmm.050947  0.312
2024 Zhang H, Wu JC. Deciphering Congenital Heart Disease Using Human Induced Pluripotent Stem Cells. Advances in Experimental Medicine and Biology. 1441: 239-252. PMID 38884715 DOI: 10.1007/978-3-031-44087-8_13  0.378
2024 Monte E, Furihata T, Wang G, Perea-Gil I, Wei E, Chaib H, Nair R, Guevara JV, Mares R, Cheng X, Zhuge Y, Black K, Serrano R, Dagan-Rosenfeld O, Maguire P, ... ... Wu JC, et al. Personalized transcriptome signatures in a cardiomyopathy stem cell biobank. Biorxiv : the Preprint Server For Biology. PMID 38798547 DOI: 10.1101/2024.05.10.593618  0.654
2024 Ren L, Jahng JWS, Belbachir N, Cook Z, Rivero GC, Perez MV, Wu JC. Generation of induced pluripotent stem cell lines from patients with LQT1 caused by heterozygous mutations in the KCNQ1 gene. Stem Cell Research. 78: 103443. PMID 38763038 DOI: 10.1016/j.scr.2024.103443  0.333
2024 Arthur Ataam J, Belbachir N, Perea-Gil I, Termglincan V, Vadgama N, Garg P, Ramchandani R, Gavidia AA, Roura S, Gálvez-Montón C, Wu JC, Bayés-Genis A, Karakikes I. Empagliflozin Attenuates Arrhythmias in an iPSC-Based Model of Hypertrophy Cardiomyopathy. Circulation. Genomic and Precision Medicine. e004526. PMID 38752368 DOI: 10.1161/CIRCGEN.123.004526  0.606
2024 Shen M, Wu JC. Empowering Valvular Heart Disease Research With Stem Cell-Derived Valve Cells. Circulation. 149: 1457-1460. PMID 38683900 DOI: 10.1161/CIRCULATIONAHA.124.068656  0.326
2024 Yu Q, Barndt RJ, Shen Y, Sallam K, Tang Y, Chan SY, Wu JC, Liu Q, Wu H. Mitigation of Stress-induced Structural Remodeling and Functional Deficiency in iPSC-CMs with PLN R9C Mutation by Promoting Autophagy. Biorxiv : the Preprint Server For Biology. PMID 38659742 DOI: 10.1101/2024.04.17.589921  0.762
2024 Lazzarino M, Zanetti M, Chen SN, Gao S, Peña B, Lam CK, Wu JC, Taylor MRG, Mestroni L, Sbaizero O. Defective Biomechanics and Pharmacological Rescue of Human Cardiomyocytes with Filamin C Truncations. International Journal of Molecular Sciences. 25. PMID 38474188 DOI: 10.3390/ijms25052942  0.687
2024 Mullen M, Kojic A, Alamana C, Canel G, Lai C, Knowles JW, Wu JC. Generation of two induced pluripotent stem cell lines from healthy patients of African American ancestry. Stem Cell Research. 76: 103322. PMID 38359472 DOI: 10.1016/j.scr.2024.103322  0.352
2023 Khokhar Y, Bhowmik A, Rui Zhao S, Cook Z, Nallamshetty S, Wu JC. Generation of induced pluripotent stem cell lines from South Asian ethnicity. Stem Cell Research. 74: 103272. PMID 38100915 DOI: 10.1016/j.scr.2023.103272  0.301
2023 Melesio J, Bonilauri B, Li A, Pang PD, Liao R, Witteles RM, Wu JC, Sallam K. Generation of two induced pluripotent stem cell lines from hereditary amyloidosis patients with polyneuropathy carrying heterozygous transthyretin (TTR) mutation. Stem Cell Research. 74: 103265. PMID 38100909 DOI: 10.1016/j.scr.2023.103265  0.699
2023 Tu C, Caudal A, Liu Y, Gorgodze N, Zhang H, Lam CK, Dai Y, Zhang A, Wnorowski A, Wu MA, Yang H, Abilez OJ, Lyu X, Narayan SM, Mestroni L, ... ... Wu JC, et al. Tachycardia-induced metabolic rewiring as a driver of contractile dysfunction. Nature Biomedical Engineering. PMID 38012305 DOI: 10.1038/s41551-023-01134-x  0.806
2023 Chen G, Orozco L, Parmisano S, Jahng JWS, Vera CD, Zhuge Y, Wu JC, Obal D. Generation of two induced pluripotent stem cell lines from patients suffering from pulmonary hypertension. Stem Cell Research. 72: 103218. PMID 37804546 DOI: 10.1016/j.scr.2023.103218  0.748
2023 Bonilauri B, Shin HS, Htet M, Yan CD, Witteles RM, Sallam K, Wu JC. Generation of two induced pluripotent stem cell lines from patients with cardiac amyloidosis carrying heterozygous transthyretin (TTR) mutation. Stem Cell Research. 72: 103215. PMID 37788558 DOI: 10.1016/j.scr.2023.103215  0.714
2023 Liu C, Shen M, Tan WLW, Chen IY, Liu Y, Yu X, Yang H, Zhang A, Liu Y, Zhao MT, Ameen M, Zhang M, Gross ER, Qi LS, Sayed N, ... Wu JC, et al. Statins improve endothelial function via suppression of epigenetic-driven EndMT. Nature Cardiovascular Research. 2: 467-485. PMID 37693816 DOI: 10.1038/s44161-023-00267-1  0.808
2023 Kong X, Belbachir N, Zeng W, Yan CD, Navada S, Perez MV, Wu JC. Generation of two induced pluripotent stem cell lines from catecholaminergic polymorphic ventricular tachycardia patients carrying RYR2 mutations. Stem Cell Research. 69: 103111. PMID 37210947 DOI: 10.1016/j.scr.2023.103111  0.314
2023 Shen M, Zhao SR, Khokhar Y, Li L, Zhou Y, Liu C, Wu JC. Protocol to generate cardiac pericytes from human induced pluripotent stem cells. Star Protocols. 4: 102256. PMID 37119139 DOI: 10.1016/j.xpro.2023.102256  0.362
2023 Sayed N, Huang Y, Nguyen K, Krejciova-Rajaniemi Z, Grawe AP, Gao T, Tibshirani R, Hastie T, Alpert A, Cui L, Kuznetsova T, Rosenberg-Hasson Y, Ostan R, Monti D, Lehallier B, ... ... Wu JC, et al. Author Correction: An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging. Nature Aging. 1: 748. PMID 37117770 DOI: 10.1038/s43587-021-00102-x  0.524
2023 Zhao L, Lee AS, Sasagawa K, Sokol J, Wang Y, Ransom RC, Zhao X, Ma C, Steininger HM, Koepke LS, Borrelli MR, Brewer RE, Lee LLY, Huang X, Ambrosi TH, ... ... Wu JC, et al. Combination of Distinct Vascular Stem/Progenitor Cells for Neovascularization and Ischemic Rescue. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 37051932 DOI: 10.1161/ATVBAHA.122.317943  0.571
2023 Ramachandran A, Livingston CE, Vite A, Corbin EA, Bennett AI, Turner KT, Lee BW, Lam CK, Wu JC, Margulies KB. Biomechanical Impact of Pathogenic MYBPC3 Truncation Variant Revealed by Dynamically Tuning In Vitro Afterload. Journal of Cardiovascular Translational Research. PMID 36877449 DOI: 10.1007/s12265-022-10348-4  0.675
2023 Shen M, Liu C, Zhao SR, Manhas A, Sundaram L, Ameen M, Wu JC. Stepwise Generation of Human Induced Pluripotent Stem Cell-Derived Cardiac Pericytes to Model Coronary Microvascular Dysfunction. Circulation. 147: 515-518. PMID 36745700 DOI: 10.1161/CIRCULATIONAHA.122.061770  0.367
2023 Eguchi A, Gonzalez AFGS, Torres-Bigio SI, Koleckar K, Birnbaum F, Zhang JZ, Wang VY, Wu JC, Artandi SE, Blau HM. TRF2 rescues telomere attrition and prolongs cell survival in Duchenne muscular dystrophy cardiomyocytes derived from human iPSCs. Proceedings of the National Academy of Sciences of the United States of America. 120: e2209967120. PMID 36719921 DOI: 10.1073/pnas.2209967120  0.328
2022 Serrano R, Feyen DAM, Bruyneel AAN, Hnatiuk AP, Vu MM, Amatya PL, Perea-Gil I, Prado M, Seeger T, Wu JC, Karakikes I, Mercola M. A deep learning platform to assess drug proarrhythmia risk. Cell Stem Cell. 30: 86-95.e4. PMID 36563695 DOI: 10.1016/j.stem.2022.12.002  0.773
2022 Ameen M, Sundaram L, Shen M, Banerjee A, Kundu S, Nair S, Shcherbina A, Gu M, Wilson KD, Varadarajan A, Vadgama N, Balsubramani A, Wu JC, Engreitz JM, Farh K, et al. Integrative single-cell analysis of cardiogenesis identifies developmental trajectories and non-coding mutations in congenital heart disease. Cell. 185: 4937-4953.e23. PMID 36563664 DOI: 10.1016/j.cell.2022.11.028  0.789
2022 Chen IY, Olshausen J, Thomas D, Lai C, McLaughlin TL, Wu JC. Generation of three induced pluripotent stem cell lines to model and investigate diseases affecting Hispanics. Stem Cell Research. 65: 102969. PMID 36427473 DOI: 10.1016/j.scr.2022.102969  0.62
2022 Yildirim Z, Kojic A, Yan CD, Wu MA, Vagelos R, Wu JC. Generation of two induced pluripotent stem cell lines from dilated cardiomyopathy patients caused by heterozygous mutations in the HCN4 gene. Stem Cell Research. 65: 102951. PMID 36332467 DOI: 10.1016/j.scr.2022.102951  0.338
2022 Chandy M, Obal D, Wu JC. Elucidating effects of environmental exposure using human-induced pluripotent stem cell disease modeling. Embo Molecular Medicine. 14: e13260. PMID 36285490 DOI: 10.15252/emmm.202013260  0.74
2022 Zhang TT, Zhao SR, Alamana C, Shen M, Parikh V, Wheeler MT, Wu JC. Generation of two induced pluripotent stem cell lines from dilated cardiomyopathy patients carrying TTN mutations. Stem Cell Research. 65: 102941. PMID 36270069 DOI: 10.1016/j.scr.2022.102941  0.326
2022 Shin HS, Thakore A, Tada Y, Pedroza AJ, Ikeda G, Chen IY, Chan D, Jaatinen KJ, Yajima S, Pfrender EM, Kawamura M, Yang PC, Wu JC, Appel EA, Fischbein MP, et al. Angiogenic stem cell delivery platform to augment post-infarction neovasculature and reverse ventricular remodeling. Scientific Reports. 12: 17605. PMID 36266453 DOI: 10.1038/s41598-022-21510-y  0.646
2022 Kojic A, Kim H, Guevara JV, Ravada S, Sallam K, Wu JC. Generation of two induced pluripotent stem cell lines from dilated cardiomyopathy patients carrying heterozygous FLNC mutations. Stem Cell Research. 64: 102928. PMID 36194907 DOI: 10.1016/j.scr.2022.102928  0.7
2022 Wang YJ, Zhang X, Lam CK, Guo H, Wang C, Zhang S, Wu JC, Snyder M, Li J. Systems analysis of de novo mutations in congenital heart diseases identified a protein network in the hypoplastic left heart syndrome. Cell Systems. PMID 36167075 DOI: 10.1016/j.cels.2022.09.001  0.662
2022 Cho S, Discher DE, Leong KW, Vunjak-Novakovic G, Wu JC. Challenges and opportunities for the next generation of cardiovascular tissue engineering. Nature Methods. 19: 1064-1071. PMID 36064773 DOI: 10.1038/s41592-022-01591-3  0.319
2022 Ramachandra AB, Wang H, Wnorowski A, Schwarz EL, Pickering J, Heiler JC, Lucian HJ, Hironaka CE, Tran NA, Liu Y, Khan MO, Obafemi O, Tada Y, Kahn AM, Sayed N, ... Wu JC, et al. Biodegradable external wrapping promotes favorable adaptation in an ovine vein graft model. Acta Biomaterialia. PMID 35995404 DOI: 10.1016/j.actbio.2022.08.029  0.559
2022 Zhao SR, Mondéjar-Parreño G, Li D, Shen M, Wu JC. Technical Applications of Microelectrode Array and Patch Clamp Recordings on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Journal of Visualized Experiments : Jove. PMID 35993757 DOI: 10.3791/64265  0.316
2022 Strimaityte D, Tu C, Yanez A, Itzhaki I, Wu H, Wu JC, Yang H. Contractility and Calcium Transient Maturation in the Human iPSC-Derived Cardiac Microfibers. Acs Applied Materials & Interfaces. 14: 35376-35388. PMID 35901275 DOI: 10.1021/acsami.2c07326  0.798
2022 Caudal A, Mondejar-Parreño G, Vera CD, Williams DR, Shenoy SP, Liang D, Wu JC. Generation of human induced pluripotent stem cell lines carrying heterozygous PLN mutation from dilated cardiomyopathy patients. Stem Cell Research. 63: 102855. PMID 35853412 DOI: 10.1016/j.scr.2022.102855  0.329
2022 Yu Z, Zhou X, Liu Z, Pastrana-Gomez V, Liu Y, Guo M, Tian L, Nelson TJ, Wang N, Mital S, Chitayat D, Wu JC, Rabinovitch M, Wu SM, Snyder MP, et al. KMT2D-NOTCH Mediates Coronary Abnormalities in Hypoplastic Left Heart Syndrome. Circulation Research. 101161CIRCRESAHA1223. PMID 35762338 DOI: 10.1161/CIRCRESAHA.122.320783  0.593
2022 Wei TT, Chandy M, Nishiga M, Zhang A, Kumar KK, Thomas D, Manhas A, Rhee S, Justesen JM, Chen IY, Wo HT, Khanamiri S, Yang JY, Seidl FJ, Burns NZ, ... ... Wu JC, et al. Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation. Cell. 185: 2387-2389. PMID 35750035 DOI: 10.1016/j.cell.2022.06.006  0.763
2022 Mullen M, Wen Tan WL, Rhee JW, Wu JC. Modeling Susceptibility to Cardiotoxicity in Cancer Therapy Using Human iPSC-Derived Cardiac Cells and Systems Biology. Heart Failure Clinics. 18: 335-347. PMID 35718410 DOI: 10.1016/j.hfc.2022.02.009  0.307
2022 Vera CD, Manhas A, Shenoy SP, Wheeler MT, Sallam K, Wu JC. Generation of two induced pluripotent stem cell lines carrying the phospholamban R14del mutation for modeling ARVD/C. Stem Cell Research. 63: 102834. PMID 35700631 DOI: 10.1016/j.scr.2022.102834  0.654
2022 Sun T, Cruz GI, Mousavi N, Marić I, Brewer A, Wong RJ, Aghaeepour N, Sayed N, Wu JC, Stevenson DK, Leonard SA, Gymrek M, Winn VD. HMOX1 Genetic Polymorphisms Display Ancestral Diversity and May Be Linked to Hypertensive Disorders in Pregnancy. Reproductive Sciences (Thousand Oaks, Calif.). PMID 35697922 DOI: 10.1007/s43032-022-01001-1  0.546
2022 Thomas D, Choi S, Alamana C, Parker KK, Wu JC. Cellular and Engineered Organoids for Cardiovascular Models. Circulation Research. 130: 1780-1802. PMID 35679369 DOI: 10.1161/CIRCRESAHA.122.320305  0.318
2022 De Jong HN, Dewey FE, Cordero P, Victorio RA, Kirillova A, Huang Y, Madhvani R, Seo K, Werdich AA, Lan F, Orcholski M, Robert Liu W, Erbilgin A, Wheeler MT, Chen R, ... ... Wu JC, et al. Wnt Signaling Interactor WTIP (Wilms Tumor Interacting Protein) Underlies Novel Mechanism for Cardiac Hypertrophy. Circulation. Genomic and Precision Medicine. 101161CIRCGEN1210035. PMID 35671065 DOI: 10.1161/CIRCGEN.121.003563  0.527
2022 Wang J, Soto F, Ma P, Ahmed R, Yang H, Chen S, Wang J, Liu C, Akin D, Fu K, Cao X, Chen P, Hsu EC, Soh HT, Stoyanova T, ... Wu JC, et al. Acoustic Fabrication of Living Cardiomyocyte-based Hybrid Biorobots. Acs Nano. PMID 35671037 DOI: 10.1021/acsnano.2c01908  0.673
2022 Gara E, Ong SG, Winkler J, Zlabinger K, Lukovic D, Merkely B, Emmert MY, Wolint P, Hoerstrup SP, Gyöngyösi M, Wu JC, Pavo N. Cell-Based HIF1α Gene Therapy Reduces Myocardial Scar and Enhances Angiopoietic Proteome, Transcriptomic and miRNA Expression in Experimental Chronic Left Ventricular Dysfunction. Frontiers in Bioengineering and Biotechnology. 10: 767985. PMID 35646882 DOI: 10.3389/fbioe.2022.767985  0.334
2022 Shen M, Liu C, Wu JC. Generation of Embryonic Origin-Specific Vascular Smooth Muscle Cells from Human Induced Pluripotent Stem Cells. Methods in Molecular Biology (Clifton, N.J.). 2429: 233-246. PMID 35507165 DOI: 10.1007/978-1-0716-1979-7_15  0.32
2022 Wei TT, Chandy M, Nishiga M, Zhang A, Kumar KK, Thomas D, Manhas A, Rhee S, Justesen JM, Chen IY, Wo HT, Khanamiri S, Yang JY, Seidl FJ, Burns NZ, ... ... Wu JC, et al. Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation. Cell. PMID 35489334 DOI: 10.1016/j.cell.2022.04.005  0.795
2022 Jahed Z, Yang Y, Tsai CT, Foster EP, McGuire AF, Yang H, Liu A, Forro C, Yan Z, Jiang X, Zhao MT, Zhang W, Li X, Li T, Pawlosky A, ... Wu JC, et al. Nanocrown electrodes for parallel and robust intracellular recording of cardiomyocytes. Nature Communications. 13: 2253. PMID 35474069 DOI: 10.1038/s41467-022-29726-2  0.659
2022 Sallam K, Thomas D, Gaddam S, Lopez N, Beck A, Beach L, Rogers AJ, Zhang H, Chen IY, Ameen M, Hiesinger W, Teuteberg JJ, Rhee JW, Wang KC, Sayed N, ... Wu JC, et al. Modeling Effects of Immunosuppressive Drugs on Human Hearts Using Induced Pluripotent Stem Cell-Derived Cardiac Organoids and Single-Cell RNA Sequencing. Circulation. 145: 1367-1369. PMID 35467958 DOI: 10.1161/CIRCULATIONAHA.121.054317  0.839
2022 Chirikian O, Feinstein S, Faynus MA, Kim AA, Lane K, Torres G, Pham J, Singh Z, Nguyen A, Thomas D, Clegg DO, Wu JC, Pruitt BL. The effects of xeno-free cryopreservation on the contractile properties of human iPSC derived cardiomyocytes. Journal of Molecular and Cellular Cardiology. PMID 35461823 DOI: 10.1016/j.yjmcc.2022.04.010  0.348
2022 Manhas A, Jahng JWS, Vera CD, Shenoy SP, Knowles JW, Wu JC. Generation of two iPSC lines from hypertrophic cardiomyopathy patients carrying MYBPC3 and PRKAG2 variants. Stem Cell Research. 61: 102774. PMID 35413566 DOI: 10.1016/j.scr.2022.102774  0.313
2022 Kim BB, Wu H, Hao YA, Pan M, Chavarha M, Zhao Y, Westberg M, St-Pierre F, Wu JC, Lin MZ. A red fluorescent protein with improved monomericity enables ratiometric voltage imaging with ASAP3. Scientific Reports. 12: 3678. PMID 35256624 DOI: 10.1038/s41598-022-07313-1  0.554
2022 Yu B, Zhao SR, Yan CD, Zhang M, Wu JC. Deconvoluting the Cells of the Human Heart with iPSC Technology: Cell Types, Protocols, and Uses. Current Cardiology Reports. PMID 35244869 DOI: 10.1007/s11886-022-01670-z  0.376
2022 Chen SN, Lam CK, Wan YW, Gao S, Malak OA, Zhao SR, Lombardi R, Ambardekar AV, Bristow MR, Cleveland J, Gigli M, Sinagra G, Graw S, Taylor MRG, Wu JC, et al. Activation of PDGFRA signaling contributes to filamin C-related arrhythmogenic cardiomyopathy. Science Advances. 8: eabk0052. PMID 35196083 DOI: 10.1126/sciadv.abk0052  0.706
2022 Cho S, Lee C, Lai C, Zhuge Y, Haddad F, Fowler M, Sallam K, Wu JC. Heterozygous LMNA mutation-carrying iPSC lines from three cardiac laminopathy patients. Stem Cell Research. 59: 102657. PMID 34999423 DOI: 10.1016/j.scr.2022.102657  0.698
2021 Mullen MMS, Wu JC. Utilization of induced pluripotent stem cells to model the molecular network regulating congenital heart disease. Cardiovascular Research. PMID 34971365 DOI: 10.1093/cvr/cvab373  0.318
2021 Ontoria-Oviedo I, Földes G, Tejedor S, Panadero J, Kitani T, Vázquez A, Wu JC, Harding SE, Sepúlveda P. Modeling Transposition of the Great Arteries with Patient-Specific Induced Pluripotent Stem Cells. International Journal of Molecular Sciences. 22. PMID 34948064 DOI: 10.3390/ijms222413270  0.751
2021 Chen IY, Vedula V, Malik SB, Liang T, Chang AY, Chung KS, Sayed N, Tsao PS, Giacomini JC, Marsden AL, Wu JC. Preoperative Computed Tomography Angiography Reveals Leaflet-Specific Calcification and Excursion Patterns in Aortic Stenosis. Circulation. Cardiovascular Imaging. 14: 1122-1132. PMID 34915729 DOI: 10.1161/CIRCIMAGING.121.012884  0.675
2021 Sayed N, Huang Y, Nguyen K, Krejciova-Rajaniemi Z, Grawe AP, Gao T, Tibshirani R, Hastie T, Alpert A, Cui L, Kuznetsova T, Rosenberg-Hasson Y, Ostan R, Monti D, Lehallier B, ... ... Wu JC, et al. An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging. Nature Aging. 1: 598-615. PMID 34888528 DOI: 10.1038/s43587-021-00082-y  0.568
2021 Belbachir N, Lai C, Rhee JW, Zhuge Y, Perez MV, Sallam K, Wu JC. Generation of two induced pluripotent stem cell lines from Brugada syndrome affected patients carrying SCN5A mutations. Stem Cell Research. 57: 102605. PMID 34856468 DOI: 10.1016/j.scr.2021.102605  0.691
2021 Zhang JZ, Zhao SR, Tu C, Pang P, Zhang M, Wu JC. Protocol to measure contraction, calcium, and action potential in human-induced pluripotent stem cell-derived cardiomyocytes. Star Protocols. 2: 100859. PMID 34746854 DOI: 10.1016/j.xpro.2021.100859  0.31
2021 Zhang H, Jahng JWS, Liu Y, Chase AJ, Perez MV, Wu JC. Generation of three induced pluripotent stem cell lines (SCVIi014-A, SCVIi015-A, and SCVIi016-A) from patients with LQT1 caused by heterozygous mutations in the KCNQ1 gene. Stem Cell Research. 55: 102492. PMID 34411974 DOI: 10.1016/j.scr.2021.102492  0.308
2021 Cao X, Jahng JWS, Lee C, Zha Y, Wheeler MT, Sallam K, Wu JC. Generation of three induced pluripotent stem cell lines from hypertrophic cardiomyopathy patients carrying MYH7 mutations. Stem Cell Research. 55: 102455. PMID 34352619 DOI: 10.1016/j.scr.2021.102455  0.683
2021 Rhee S, Paik DT, Yang JY, Nagelberg D, Williams I, Tian L, Roth R, Chandy M, Ban J, Belbachir N, Kim S, Zhang H, Phansalkar R, Wong KM, King DA, ... ... Wu JC, et al. Endocardial/endothelial angiocrines regulate cardiomyocyte development and maturation and induce features of ventricular non-compaction. European Heart Journal. PMID 34279605 DOI: 10.1093/eurheartj/ehab298  0.308
2021 Jahng JWS, Zhang M, Wu JC. The role of metabolism in directed differentiation versus trans-differentiation of cardiomyocytes. Seminars in Cell & Developmental Biology. PMID 34074592 DOI: 10.1016/j.semcdb.2021.05.018  0.308
2021 Hong L, Zhang M, Ly OT, Chen H, Sridhar A, Lambers E, Chalazan B, Youn SW, Maienschein-Cline M, Feferman L, Ong SG, Wu JC, Rehman J, Darbar D. Human induced pluripotent stem cell-derived atrial cardiomyocytes carrying an SCN5A mutation identify nitric oxide signaling as a mediator of atrial fibrillation. Stem Cell Reports. PMID 34019817 DOI: 10.1016/j.stemcr.2021.04.019  0.641
2021 Chang ACY, Pardon G, Chang ACH, Wu H, Ong SG, Eguchi A, Ancel S, Holbrook C, Ramunas J, Ribeiro AJS, LaGory EL, Wang H, Koleckar K, Giaccia A, Mack DL, ... ... Wu JC, et al. Increased tissue stiffness triggers contractile dysfunction and telomere shortening in dystrophic cardiomyocytes. Stem Cell Reports. PMID 34019816 DOI: 10.1016/j.stemcr.2021.04.018  0.81
2021 Cho S, Lee C, Skylar-Scott MA, Heilshorn SC, Wu JC. Reconstructing the heart using iPSCs: Engineering strategies and applications. Journal of Molecular and Cellular Cardiology. PMID 33895197 DOI: 10.1016/j.yjmcc.2021.04.006  0.301
2021 Chour T, Tian L, Lau E, Thomas D, Itzhaki I, Malak O, Zhang JZ, Qin X, Wardak M, Liu Y, Chandy M, Black KE, Lam MP, Neofytou E, Wu JC. Method for selective ablation of undifferentiated human pluripotent stem cell populations for cell-based therapies. Jci Insight. 6. PMID 33830086 DOI: 10.1172/jci.insight.142000  0.69
2021 Shen M, Quertermous T, Fischbein MP, Wu JC. Generation of Vascular Smooth Muscle Cells From Induced Pluripotent Stem Cells: Methods, Applications, and Considerations. Circulation Research. 128: 670-686. PMID 33818124 DOI: 10.1161/CIRCRESAHA.120.318049  0.358
2021 Thomas D, Kim H, Lopez N, Wu JC. Fabrication of 3D Cardiac Microtissue Arrays using Human iPSC-Derived Cardiomyocytes, Cardiac Fibroblasts, and Endothelial Cells. Journal of Visualized Experiments : Jove. PMID 33779590 DOI: 10.3791/61879  0.367
2021 Li D, Shao NY, Moonen JR, Zhao Z, Shi M, Otsuki S, Wang L, Nguyen T, Yan E, Marciano DP, Contrepois K, Li CG, Wu JC, Snyder MP, Rabinovitch M. ALDH1A3 Coordinates Metabolism with Gene Regulation in Pulmonary Arterial Hypertension. Circulation. PMID 33764154 DOI: 10.1161/CIRCULATIONAHA.120.048845  0.645
2021 Jahng JWS, Black KE, Liu L, Bae HR, Perez M, Ashley EA, Sallam K, Wu JC. Generation of three induced pluripotent stem cell lines, SCVIi003-A, SCVIi004-A, SCVIi005-A, from patients with ARVD/C caused by heterozygous mutations in the PKP2 gene. Stem Cell Research. 53: 102284. PMID 33743362 DOI: 10.1016/j.scr.2021.102284  0.692
2021 Maas RGC, Lee S, Harakalova M, Snijders Blok CJB, Goodyer WR, Hjortnaes J, Doevendans PAFM, Van Laake LW, van der Velden J, Asselbergs FW, Wu JC, Sluijter JPG, Wu SM, Buikema JW. Massive expansion and cryopreservation of functional human induced pluripotent stem cell-derived cardiomyocytes. Star Protocols. 2: 100334. PMID 33615277 DOI: 10.1016/j.xpro.2021.100334  0.389
2021 Chirikian O, Goodyer WR, Dzilic E, Serpooshan V, Buikema JW, McKeithan W, Wu H, Li G, Lee S, Merk M, Galdos F, Beck A, Ribeiro AJS, Paige S, Mercola M, ... Wu JC, et al. CRISPR/Cas9-based targeting of fluorescent reporters to human iPSCs to isolate atrial and ventricular-specific cardiomyocytes. Scientific Reports. 11: 3026. PMID 33542270 DOI: 10.1038/s41598-021-81860-x  0.656
2021 Shah PP, Lv W, Rhoades JH, Poleshko A, Abbey D, Caporizzo MA, Linares-Saldana R, Heffler JG, Sayed N, Thomas D, Wang Q, Stanton LJ, Bedi K, Morley MP, Cappola TP, ... ... Wu JC, et al. Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes. Cell Stem Cell. PMID 33529599 DOI: 10.1016/j.stem.2020.12.016  0.644
2021 Cheng J, Tsuda M, Okolotowicz K, Dwyer M, Bushway PJ, Colas AR, Lancman JJ, Schade D, Perea-Gil I, Bruyneel AAN, Lee J, Vadgama N, Quach J, McKeithan WL, Biechele TL, ... Wu JC, et al. Small-molecule probe reveals a kinase cascade that links stress signaling to TCF/LEF and Wnt responsiveness. Cell Chemical Biology. PMID 33503403 DOI: 10.1016/j.chembiol.2021.01.001  0.579
2021 Lam CK, Wu JC. Clinical Trial in a Dish: Using Patient-Derived Induced Pluripotent Stem Cells to Identify Risks of Drug-Induced Cardiotoxicity. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120314695. PMID 33472401 DOI: 10.1161/ATVBAHA.120.314695  0.703
2020 Chandy M, Rhee JW, Ozen MO, Williams DR, Pepic L, Liu C, Zhang H, Malisa J, Lau E, Demirci U, Wu JC. Atlas of Exosomal microRNAs Secreted From Human iPSC-Derived Cardiac Cell Types. Circulation. 142: 1794-1796. PMID 33136510 DOI: 10.1161/CIRCULATIONAHA.120.048364  0.641
2020 Wu JC, Wardak M, Chen IY. Sanjiv Sam Gambhir, MD, PhD (1962-2020). Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology. PMID 33131016 DOI: 10.1007/s12350-020-02404-w  0.469
2020 Liu Y, Hanley T, Chen H, Long SR, Gambhir SS, Cheng Z, Wu JC, Fakhri GE, Anvari B, Zaman RT. Author Correction: Non-Invasive Photoacoustic Imaging of In Vivo Mice with Erythrocyte Derived Optical Nanoparticles to Detect CAD/MI. Scientific Reports. 10: 19102. PMID 33127974 DOI: 10.1038/s41598-020-75966-x  0.456
2020 Jabart E, Molho J, Sin K, Stansfield B, Kazmouz SG, Ventro D, Gardner K, Wu JC, Churko JM. Single-cell protein expression of hiPSC-derived cardiomyocytes using Single-Cell Westerns. Journal of Molecular and Cellular Cardiology. PMID 33010256 DOI: 10.1016/j.yjmcc.2020.09.012  0.744
2020 Yang H, Shao N, Holmström A, Zhao X, Chour T, Chen H, Itzhaki I, Wu H, Ameen M, Cunningham NJ, Tu C, Zhao MT, Tarantal AF, Abilez OJ, Wu JC. Transcriptome Analysis of Non-Human Primate Induced Pluripotent Stem Cell-Derived Cardiomyocytes in 2D Monolayer Culture versus 3D Engineered Heart Tissue. Cardiovascular Research. PMID 33002105 DOI: 10.1093/cvr/cvaa281  0.841
2020 Paik DT, Tian L, Williams IM, Rhee S, Zhang H, Liu C, Mishra R, Wu SM, Red-Horse K, Wu JC. Single-Cell RNA-seq Unveils Unique Transcriptomic Signatures of Organ-Specific Endothelial Cells. Circulation. PMID 32929989 DOI: 10.1161/Circulationaha.119.041433  0.344
2020 Huang CY, Li LH, Hsu WT, Cheng YC, Nicholson MW, Liu CL, Ting CY, Ko HW, Syu SH, Wen CH, Yan Z, Huang HP, Su HL, Chiang PM, Shen CN, ... ... Wu JY, ... ... Wu JC, et al. Copy number variant hotspots in Han Taiwanese population induced pluripotent stem cell lines - lessons from establishing the Taiwan human disease iPSC Consortium Bank. Journal of Biomedical Science. 27: 92. PMID 32887585 DOI: 10.1186/S12929-020-00682-7  0.431
2020 Miao Y, Tian L, Martin M, Paige SL, Galdos FX, Li J, Klein A, Zhang H, Ma N, Wei Y, Stewart M, Lee S, Moonen JR, Zhang B, Grossfeld P, ... ... Wu JC, et al. Intrinsic Endocardial Defects Contribute to Hypoplastic Left Heart Syndrome. Cell Stem Cell. PMID 32810435 DOI: 10.1016/J.Stem.2020.07.015  0.681
2020 Kernik DC, Yang PC, Kurokawa J, Wu JC, Clancy CE. A computational model of induced pluripotent stem-cell derived cardiomyocytes for high throughput risk stratification of KCNQ1 genetic variants. Plos Computational Biology. 16: e1008109. PMID 32797034 DOI: 10.1371/Journal.Pcbi.1008109  0.364
2020 Obal D, Wu JC. Induced Pluripotent Stem Cells as a Platform to Understand Patient-Specific Responses to Opioids and Anaesthetics. British Journal of Pharmacology. PMID 32767563 DOI: 10.1111/Bph.15228  0.75
2020 Wilson KD, Ameen M, Guo H, Abilez OJ, Tian L, Mumbach MR, Diecke S, Qin X, Liu Y, Yang H, Ma N, Gaddam S, Cunningham NJ, Gu M, Neofytou E, ... ... Wu JC, et al. Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human Primates. Developmental Cell. PMID 32763147 DOI: 10.1016/J.Devcel.2020.07.006  0.827
2020 Sayed N, Liu C, Ameen M, Himmati F, Zhang JZ, Khanamiri S, Moonen JR, Wnorowski A, Cheng L, Rhee JW, Gaddam S, Wang KC, Sallam K, Boyd JH, Woo YJ, ... ... Wu JC, et al. Clinical trial in a dish using iPSCs shows lovastatin improves endothelial dysfunction and cellular cross-talk in LMNA cardiomyopathy. Science Translational Medicine. 12. PMID 32727917 DOI: 10.1126/Scitranslmed.Aax9276  0.799
2020 Feyen DAM, McKeithan WL, Bruyneel AAN, Spiering S, Hörmann L, Ulmer B, Zhang H, Briganti F, Schweizer M, Hegyi B, Liao Z, Pölönen RP, Ginsburg KS, Lam CK, Serrano R, ... ... Wu JC, et al. Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes. Cell Reports. 32: 107925. PMID 32697997 DOI: 10.1016/J.Celrep.2020.107925  0.733
2020 Zhang H, Shen M, Wu JC. Generation of Quiescent Cardiac Fibroblasts Derived from Human Induced Pluripotent Stem Cells. Methods in Molecular Biology (Clifton, N.J.). PMID 32671814 DOI: 10.1007/7651_2020_300  0.458
2020 Rhee JW, Yi H, Thomas D, Lam CK, Belbachir N, Tian L, Qin X, Malisa J, Lau E, Paik DT, Kim Y, Choi BS, Sayed N, Sallam K, Liao R, ... Wu JC, et al. Modeling Secondary Iron Overload Cardiomyopathy with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Cell Reports. 32: 107886. PMID 32668256 DOI: 10.1016/J.Celrep.2020.107886  0.793
2020 Buikema JW, Lee S, Goodyer WR, Maas RG, Chirikian O, Li G, Miao Y, Paige SL, Lee D, Wu H, Paik DT, Rhee S, Tian L, Galdos FX, Puluca N, ... ... Wu JY, ... ... Wu JC, et al. Wnt Activation and Reduced Cell-Cell Contact Synergistically Induce Massive Expansion of Functional Human iPSC-Derived Cardiomyocytes. Cell Stem Cell. 27: 50-63.e5. PMID 32619518 DOI: 10.1016/J.Stem.2020.06.001  0.682
2020 Zhang JX, Lau E, Paik DT, Zhuge Y, Wu JC. High-throughput Preparation of DNA, RNA, and Protein from Cryopreserved Human iPSCs for Multi-omics Analysis. Current Protocols in Stem Cell Biology. 54: e114. PMID 32584494 DOI: 10.1002/Cpsc.114  0.608
2020 Dainis A, Zaleta-Rivera K, Ribeiro A, Chang ACH, Shang C, Lan F, Burridge PW, Liu WR, Wu JC, Chang ACY, Pruitt BL, Wheeler M, Ashley EA. Silencing of MYH7 ameliorates disease phenotypes in human iPSC-Cardiomyocytes. Physiological Genomics. PMID 32567507 DOI: 10.1152/Physiolgenomics.00021.2020  0.749
2020 Wardak M, Gowrishankar G, Zhao X, Liu Y, Chang E, Namavari M, Haywood T, Gabr MT, Neofytou E, Chour T, Qin X, Vilches-Moure JG, Hardy J, Contag CH, McConnell MV, ... Wu JC, et al. Molecular Imaging of Infective Endocarditis With 6''-[F]Fluoromaltotriose Positron Emission Tomography-Computed Tomography. Circulation. 141: 1729-1731. PMID 32453662 DOI: 10.1161/Circulationaha.119.043924  0.385
2020 Ramachandra CJA, Chua J, Cong S, Kp MMJ, Shim W, Wu JC, Hausenloy DJ. Human induced pluripotent stem cells for modelling metabolic perturbations and impaired bioenergetics underlying cardiomyopathies. Cardiovascular Research. PMID 32365198 DOI: 10.1093/Cvr/Cvaa125  0.432
2020 Lee S, Yang H, Chen C, Venkatraman S, Darsha A, Wu SM, Wu JC, Seeger T. Simple Lithography-Free Single Cell Micropatterning using Laser-Cut Stencils. Journal of Visualized Experiments : Jove. PMID 32310234 DOI: 10.3791/60888  0.815
2020 Tian L, Oikonomopoulos A, Liu C, Kitani T, Shrestha R, Chen CL, Ong SG, Smeets M, Karakikes I, Sayed N, Wu JC. Molecular Signatures of Beneficial Class Effects of Statins on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Circulation. 141: 1208-1210. PMID 32250699 DOI: 10.1161/Circulationaha.118.035906  0.832
2020 Liu Y, Hanley T, Chen H, Long SR, Gambhir SS, Cheng Z, Wu JC, Fakhri GE, Anvari B, Zaman RT. Non-Invasive Photoacoustic Imaging of In Vivo Mice with Erythrocyte Derived Optical Nanoparticles to Detect CAD/MI. Scientific Reports. 10: 5983. PMID 32249814 DOI: 10.1038/S41598-020-62868-1  0.531
2020 Paik DT, Cho S, Tian L, Chang HY, Wu JC. Single-cell RNA sequencing in cardiovascular development, disease and medicine. Nature Reviews. Cardiology. PMID 32231331 DOI: 10.1038/S41569-020-0359-Y  0.446
2020 Kamdar F, Das S, Gong W, Klaassen Kamdar A, Meyers TA, Shah P, Ervasti JM, Townsend D, Kamp TJ, Wu JC, Garry MG, Zhang J, Garry DJ. Stem Cell-Derived Cardiomyocytes and Beta-Adrenergic Receptor Blockade in Duchenne Muscular Dystrophy Cardiomyopathy. Journal of the American College of Cardiology. 75: 1159-1174. PMID 32164890 DOI: 10.1016/J.Jacc.2019.12.066  0.381
2020 LaRocca TJ, Seeger T, Prado M, Perea-Gil I, Neofytou E, Mecham BH, Ameen M, Chang ACY, Pandey G, Wu JC, Karakikes I. Pharmacological Silencing of MicroRNA-152 Prevents Pressure Overload-Induced Heart Failure. Circulation. Heart Failure. 13: e006298. PMID 32160771 DOI: 10.1161/Circheartfailure.119.006298  0.786
2020 Santoso MR, Ikeda G, Tada Y, Jung JH, Vaskova E, Sierra RG, Gati C, Goldstone AB, von Bornstaedt D, Shukla P, Wu JC, Wakatsuki S, Woo YJ, Yang PC. Exosomes From Induced Pluripotent Stem Cell-Derived Cardiomyocytes Promote Autophagy for Myocardial Repair. Journal of the American Heart Association. 9: e014345. PMID 32131688 DOI: 10.1161/Jaha.119.014345  0.438
2020 Han D, Wu JC. Using Bioengineered Bioluminescence to Track Stem Cell Transplantation In Vivo. Methods in Molecular Biology (Clifton, N.J.). 2126: 1-11. PMID 32112374 DOI: 10.1007/978-1-0716-0364-2_1  0.402
2020 Kitani T, Tian L, Zhang T, Itzhaki I, Zhang JZ, Ma N, Liu C, Rhee JW, Romfh A, Lui GK, Wu JC. RNA Sequencing Analysis of Induced Pluripotent Stem Cell-Derived Cardiomyocytes from Congenital Heart Disease Patients. Circulation Research. PMID 32070195 DOI: 10.1161/Circresaha.119.315653  0.776
2020 Paik DT, Chandy M, Wu JC. Patient and Disease-Specific Induced Pluripotent Stem Cells for Discovery of Personalized Cardiovascular Drugs and Therapeutics. Pharmacological Reviews. 72: 320-342. PMID 31871214 DOI: 10.1124/Pr.116.013003  0.408
2019 Wu JC, Rhee JW, Sallam K. Electronic Cigarettes: Where There Is Smoke There Is Disease. Journal of the American College of Cardiology. 74: 3121-3123. PMID 31856968 DOI: 10.1016/J.Jacc.2019.10.029  0.606
2019 Smith A, Choi E, Gray K, Macadangdang J, Ahn EH, Clark EC, Laflamme M, Wu JC, Murry CE, Tung L, Kim DH. NanoMEA: a tool for high-throughput, electrophysiological phenotyping of patterned excitable cells. Nano Letters. PMID 31845810 DOI: 10.1021/Acs.Nanolett.9B04152  0.406
2019 Lau E, Han Y, Williams DR, Thomas CT, Shrestha R, Wu JC, Lam MPY. Splice-Junction-Based Mapping of Alternative Isoforms in the Human Proteome. Cell Reports. 29: 3751-3765.e5. PMID 31825849 DOI: 10.1016/J.Celrep.2019.11.026  0.626
2019 Wnorowski A, Sharma A, Chen H, Wu H, Shao NY, Sayed N, Liu C, Countryman S, Stodieck LS, Rubins KH, Wu SM, Lee PHU, Wu JC. Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function. Stem Cell Reports. PMID 31708475 DOI: 10.1016/J.Stemcr.2019.10.006  0.836
2019 Pang L, Sager P, Yang X, Shi H, Sannajust F, Brock M, Wu JC, Abi-Gerges N, Lyn-Cook B, Berridge BR, Stockbridge N. Workshop Report: FDA Workshop on Improving Cardiotoxicity Assessment With Human-Relevant Platforms. Circulation Research. 125: 855-867. PMID 31600125 DOI: 10.1161/Circresaha.119.315378  0.308
2019 Sass G, Tsamo AT, Chounda GAM, Nangmo PK, Sayed N, Bozzi A, Wu JC, Nkengfack AE, Stevens DA. Vismione B Interferes with Infection of Vero Cells and Human Stem Cell-Derived Cardiomyocytes. The American Journal of Tropical Medicine and Hygiene. PMID 31571568 DOI: 10.4269/Ajtmh.19-0350  0.795
2019 Gintant G, Burridge P, Gepstein L, Harding S, Herron T, Hong C, Jalife J, Wu JC. Use of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Preclinical Cancer Drug Cardiotoxicity Testing: A Scientific Statement From the American Heart Association. Circulation Research. RES0000000000000291. PMID 31533542 DOI: 10.1161/Res.0000000000000291  0.704
2019 Tu C, Mezynski R, Wu JC. Improving the engraftment and integration of cell transplantation for cardiac regeneration. Cardiovascular Research. PMID 31504255 DOI: 10.1093/Cvr/Cvz237  0.367
2019 Hajipour MJ, Mehrani M, Abbasi SH, Amin A, Kassaian SE, Garbern JC, Caracciolo G, Zanganeh S, Chitsazan M, Aghaverdi H, Kamali Shahri SM, Ashkarran A, Raoufi M, Bauser-Heaton H, Zhang J, ... ... Wu JC, et al. Nanoscale Technologies for Prevention and Treatment of Heart Failure: Challenges and Opportunities. Chemical Reviews. PMID 31490059 DOI: 10.1021/Acs.Chemrev.8B00323  0.349
2019 Wu JC, Garg P, Yoshida Y, Yamanaka S, Gepstein L, Hulot JS, Knollmann BC, Schwartz PJ. Towards Precision Medicine With Human iPSCs for Cardiac Channelopathies. Circulation Research. 125: 653-658. PMID 31465267 DOI: 10.1161/Circresaha.119.315209  0.414
2019 Wirka RC, Wagh D, Paik DT, Pjanic M, Nguyen T, Miller CL, Kundu R, Nagao M, Coller J, Koyano TK, Fong R, Woo YJ, Liu B, Montgomery SB, Wu JC, et al. Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis. Nature Medicine. PMID 31359001 DOI: 10.1038/S41591-019-0512-5  0.351
2019 Loskill P, Wu JC. Stem cell based human organ-on-a-chip models for drug discovery and development. Advanced Drug Delivery Reviews. 140: 1-2. PMID 31352955 DOI: 10.1016/J.Addr.2019.07.004  0.407
2019 Ouyang X, Telli ML, Wu JC. Induced Pluripotent Stem Cell-Based Cancer Vaccines. Frontiers in Immunology. 10: 1510. PMID 31338094 DOI: 10.3389/Fimmu.2019.01510  0.317
2019 Blinova K, Schocken D, Patel D, Daluwatte C, Vicente J, Wu JC, Strauss DG. Clinical trial in a dish: personalized stem cell derived cardiomyocyte assay compared to clinical trial results for two QT prolonging drugs. Clinical and Translational Science. PMID 31328865 DOI: 10.1111/Cts.12674  0.332
2019 Lee J, Termglinchan V, Diecke S, Itzhaki I, Lam CK, Garg P, Lau E, Greenhaw M, Seeger T, Wu H, Zhang JZ, Chen X, Gil IP, Ameen M, Sallam K, ... ... Wu JC, et al. Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy. Nature. PMID 31316208 DOI: 10.1038/S41586-019-1406-X  0.812
2019 Zhang H, Tian L, Shen M, Wu H, Gu M, Tu C, Paik DT, Wu JC. Generation of Quiescent Cardiac Fibroblasts from Human Induced Pluripotent Stem Cells for In Vitro Modeling of Cardiac Fibrosis. Circulation Research. PMID 31288631 DOI: 10.1161/Circresaha.119.315491  0.801
2019 Goodyer WR, Beyersdorf B, Paik DT, Tian L, Li G, Buikema JW, Chirikian O, Choi S, Venkatraman S, Adams EL, Tessier-Lavigne M, Wu JC, Wu SM. Transcriptomic Profiling of the Developing Cardiac Conduction System at Single-Cell Resolution. Circulation Research. PMID 31284824 DOI: 10.1161/Circresaha.118.314578  0.385
2019 Kernik DC, Morotti S, Wu H, Garg P, Duff HJ, Kurokawa J, Jalife J, Wu JC, Grandi E, Clancy CE. A computational model of induced pluripotent stem-cell derived cardiomyocytes incorporating experimental variability from multiple data sources. The Journal of Physiology. PMID 31278749 DOI: 10.1113/Jp277724  0.691
2019 Williams IM, Wu JC. Generation of Endothelial Cells From Human Pluripotent Stem Cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 39: 1317-1329. PMID 31242035 DOI: 10.1161/Atvbaha.119.312265  0.438
2019 Wu H, Yang H, Rhee JW, Zhang JZ, Lam CK, Sallam K, Chang ACY, Ma N, Lee J, Zhang H, Blau HM, Bers DM, Wu JC. Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients. European Heart Journal. PMID 31219556 DOI: 10.1093/Eurheartj/Ehz326  0.834
2019 Sass G, Madigan RT, Joubert LM, Bozzi A, Sayed N, Wu JC, Stevens DA. A Combination of Itraconazole and Amiodarone Is Highly Effective against Infection of Human Stem Cell-Derived Cardiomyocytes. The American Journal of Tropical Medicine and Hygiene. PMID 31219005 DOI: 10.4269/Ajtmh.19-0023  0.811
2019 Lee WH, Ong SG, Zhou Y, Tian L, Bae HR, Baker N, Whitlatch A, Mohammadi L, Guo H, Nadeau KC, Springer ML, Schick SF, Bhatnagar A, Wu JC. Modeling Cardiovascular Risks of E-Cigarettes With Human-Induced Pluripotent Stem Cell-Derived Endothelial Cells. Journal of the American College of Cardiology. 73: 2722-2737. PMID 31146818 DOI: 10.1016/J.Jacc.2019.03.476  0.677
2019 Li G, Tian L, Goodyer W, Kort EJ, Buikema JW, Xu A, Wu J, Jovinge S, Wu SM. Single cell expression analysis reveals anatomical and cell cycle-dependent transcriptional shifts during heart development. Development (Cambridge, England). PMID 31142541 DOI: 10.1242/Dev.173476  0.433
2019 Belbachir N, Portero V, Al Sayed ZR, Gourraud JB, Dilasser F, Jesel L, Guo H, Wu H, Gaborit N, Guilluy C, Girardeau A, Bonnaud S, Simonet F, Karakachoff M, Pattier S, ... ... Wu JC, et al. RRAD mutation causes electrical and cytoskeletal defects in cardiomyocytes derived from a familial case of Brugada syndrome. European Heart Journal. PMID 31114854 DOI: 10.1093/Eurheartj/Ehz308  0.62
2019 Bozzi A, Sayed N, Matsa E, Sass G, Neofytou E, Clemons KV, Correa-Oliveira R, Stevens DA, Wu JC. Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes as a Model to Study Trypanosoma cruzi Infection. Stem Cell Reports. PMID 31105048 DOI: 10.1016/J.Stemcr.2019.04.017  0.825
2019 Ebert A, Joshi AU, Andorf S, Dai Y, Sampathkumar S, Chen H, Li Y, Garg P, Toischer K, Hasenfuβ G, Mochly Rosen D, Wu JC. Proteasome-Dependent Regulation of Distinct Metabolic States During Long-Term Culture of Human iPSC-Derived Cardiomyocytes. Circulation Research. PMID 31104567 DOI: 10.1161/Circresaha.118.313973  0.74
2019 Lam CK, Tian L, Belbachir N, Shrestha R, Ma N, Kitani T, Rhee JW, Wnorowski A, Wu JC. Identifying the Transcriptome Signatures of Calcium Channel Blockers in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Circulation Research. PMID 31079550 DOI: 10.1161/Circresaha.118.314202  0.808
2019 Oh Y, Park Y, Cho JH, Wu H, Paulk NK, Liu LX, Kim N, Kay MA, Wu JC, Lin MZ. An orange calcium-modulated bioluminescent indicator for non-invasive activity imaging. Nature Chemical Biology. PMID 30936501 DOI: 10.1038/S41589-019-0256-Z  0.584
2019 Zhang JZ, Termglinchan V, Shao NY, Itzhaki I, Liu C, Ma N, Tian L, Wang VY, Chang ACY, Guo H, Kitani T, Wu H, Lam CK, Kodo K, Sayed N, ... ... Wu JC, et al. A Human iPSC Double-Reporter System Enables Purification of Cardiac Lineage Subpopulations with Distinct Function and Drug Response Profiles. Cell Stem Cell. PMID 30880024 DOI: 10.1016/J.Stem.2019.02.015  0.83
2019 Kitani T, Ong SG, Lam CK, Rhee JW, Zhang JZ, Oikonomopoulos A, Ma N, Tian L, Lee J, Telli ML, Witteles RM, Sharma A, Sayed N, Wu JC. Human Induced Pluripotent Stem Cell Model of Trastuzumab-Induced Cardiac Dysfunction in Breast Cancer Patients. Circulation. PMID 30866650 DOI: 10.1161/Circulationaha.118.037357  0.813
2019 Guo H, Tian L, Zhang JZ, Kitani T, Paik DT, Lee WH, Wu JC. Single-Cell RNA Sequencing of Human Embryonic Stem Cell Differentiation Delineates Adverse Effects of Nicotine on Embryonic Development. Stem Cell Reports. PMID 30827876 DOI: 10.1016/J.Stemcr.2019.01.022  0.789
2019 Sayed N, Ameen M, Wu JC. Personalized Medicine in Cardio-Oncology: The Role of iPSC. Cardiovascular Research. PMID 30768178 DOI: 10.1093/Cvr/Cvz024  0.692
2019 Berry JL, Zhu W, Tang YL, Krishnamurthy P, Ge Y, Cooke JP, Chen Y, Garry DJ, Yang HT, Rajasekaran NS, Koch WJ, Li S, Domae K, Qin G, Cheng K, ... ... Wu JC, et al. Convergences of Life Sciences and Engineering in Understanding and Treating Heart Failure. Circulation Research. 124: 161-169. PMID 30605412 DOI: 10.1161/Circresaha.118.314216  0.617
2019 Kitani T, Ong S, Lam CK, Rhee J, Zhang JZ, Oikonomopoulos A, Ma N, Tian L, Lee J, Telli ML, Witteles RM, Sharma A, Sayed N, Wu JC. Abstract 782: Human-induced Pluripotent Stem Cell-derived Cardiomyocytes as a Model for Trastuzumab-Induced Cardiac Dysfunction Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.782  0.844
2019 Paik DT, Tian L, Williams IM, Liu C, Zhang H, Williams D, Mishra R, Wu SM, Wu JC. Abstract 642: Single-Cell RNA-seq Unveils Unique Transcriptomic Signatures of Organ-Specific Endothelial Cells Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.642  0.331
2019 Wei T", Chandy M, Chen IY, Wo H, Khanamiri S, Nishiga M, Seidl F, Sayed N, Liu C, Rhee J, Obal D, Chour T, Wu JC. Abstract 497: Studying Cardiovascular Effects of Marijuana on Healthy Individuals Using Human Derived Induced Pluripotent Stem Cells Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.497  0.714
2019 Chandy M, Sayed N, Lau E, Liu C, Wei T, Chen IY, Thomas D, Rhee J, Oh B, Pepic L, Husain M, Quertermous T, Nallamshetty S, Wu J. Abstract 402: Adiponectin Receptor 3 is Associated With Endothelial Nitric Oxide Synthase Dysfunction and Predicts Insulin Resistance in South Asians Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.402  0.758
2019 Lam CK, Tian L, Belbachir N, Wnorowski A, Shrestha R, Ma N, Kitani T, Rhee JW, Wu JC. Abstract 237: Identifying the Transcriptome Signature of Calcium Channel Blocker in Human iPSC-Derived Cardiomyocytes Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.237  0.718
2019 Lau E, Chandy MJ, Williams DR, Shrestha R, Rhee J, Wu JC. Abstract 119: Multi-Omics Investigation of Cardiomyocyte-to-Fibroblast Crosstalk in Human iPSC Models Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.119  0.662
2019 Gyongyosi M, Lukovic D, Pavo N, Gugerell A, Winkler J, Spannbauer A, Pavo IJ, Michel-Behnke I, Emmert MY, Hoerstrup SP, Marian T, Balkay L, Trencsenyi G, Wu JC, Zlabinger K. P5990In vivo tracking of long-term survival of xenogeneic porcine mesenchymal stem cells seeded on tissue-engineered heart valve implanted in sheep European Heart Journal. 40. DOI: 10.1093/Eurheartj/Ehz746.0711  0.318
2019 Qin X, Han D, Wu JC. Molecular imaging of cardiac regenerative medicine Current Opinion in Biomedical Engineering. 9: 66-73. DOI: 10.1016/J.Cobme.2019.04.006  0.428
2019 Kernik DC, Morotti S, Priyanka G, Wu JC, Jalife J, Grandi E, Clancy CE. A Computational Approach to Predict Mechanisms of Phenotypic Variability in Induced Pluripotent Stem Cell-Derived Cardiomyocytes Biophysical Journal. 116: 101a. DOI: 10.1016/J.Bpj.2018.11.580  0.412
2018 Chen H, Zhang A, Wu JC. Harnessing cell pluripotency for cardiovascular regenerative medicine. Nature Biomedical Engineering. 2: 392-398. PMID 31011193 DOI: 10.1038/S41551-018-0244-8  0.499
2018 Seeger T, Shrestha R, Lam CK, Chen C, McKeithan WL, Lau E, Wnorowski A, McMullen G, Greenhaw M, Lee J, Oikonomopoulos A, Lee S, Yang H, Mercola M, Wheeler M, ... ... Wu JC, et al. A Premature Termination Codon Mutation in MYBPC3 Causes Hypertrophic Cardiomyopathy via Chronic Activation of Nonsense-Mediated Decay. Circulation. PMID 30586709 DOI: 10.1161/Circulationaha.118.034624  0.797
2018 Huang NF, Serpooshan V, Morris VB, Sayed N, Pardon G, Abilez OJ, Nakayama KH, Pruitt BL, Wu SM, Yoon YS, Zhang J, Wu JC. Big bottlenecks in cardiovascular tissue engineering. Communications Biology. 1: 199. PMID 30480100 DOI: 10.1038/s42003-018-0202-8  0.598
2018 Qin X, Chen H, Yang H, Wu H, Zhao X, Wang H, Chour T, Neofytou E, Ding D, Daldrup-Link H, Heilshorn SC, Li K, Wu JC. Photoacoustic Imaging of Embryonic Stem Cell-Derived Cardiomyocytes in Living Hearts with Ultrasensitive Semiconducting Polymer Nanoparticles. Advanced Functional Materials. 28. PMID 30473658 DOI: 10.1002/Adfm.201704939  0.822
2018 Churko JM, Garg P, Treutlein B, Venkatasubramanian M, Wu H, Lee J, Wessells QN, Chen SY, Chen WY, Chetal K, Mantalas G, Neff N, Jabart E, Sharma A, Nolan GP, ... ... Wu JC, et al. Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis. Nature Communications. 9: 4906. PMID 30464173 DOI: 10.1038/S41467-018-07333-4  0.832
2018 Sharma A, McKeithan WL, Serrano R, Kitani T, Burridge PW, Del Álamo JC, Mercola M, Wu JC. Use of human induced pluripotent stem cell-derived cardiomyocytes to assess drug cardiotoxicity. Nature Protocols. PMID 30413796 DOI: 10.1038/S41596-018-0076-8  0.819
2018 Cao Y, Chen H, Qiu R, Hanna M, Ma E, Hjort M, Zhang A, Lewis RS, Wu JC, Melosh NA. Universal intracellular biomolecule delivery with precise dosage control. Science Advances. 4: eaat8131. PMID 30402539 DOI: 10.1126/Sciadv.Aat8131  0.343
2018 Lau E, Paik DT, Wu JC. Systems-Wide Approaches in Induced Pluripotent Stem Cell Models. Annual Review of Pathology. PMID 30379619 DOI: 10.1146/Annurev-Pathmechdis-012418-013046  0.689
2018 Tu C, Chao BS, Wu JC. Strategies for Improving the Maturity of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Circulation Research. 123: 512-514. PMID 30355143 DOI: 10.1161/Circresaha.118.313472  0.479
2018 Lau E, Venkatraman V, Thomas CT, Wu JC, Van Eyk JE, Lam MPY. Identifying High-Priority Proteins Across the Human Diseasome Using Semantic Similarity. Journal of Proteome Research. PMID 30256117 DOI: 10.1021/Acs.Jproteome.8B00393  0.577
2018 Liu Q, Van Bortle K, Zhang Y, Zhao MT, Zhang JZ, Geller BS, Gruber JJ, Jiang C, Wu JC, Snyder MP. Disruption of mesoderm formation during cardiac differentiation due to developmental exposure to 13-cis-retinoic acid. Scientific Reports. 8: 12960. PMID 30154523 DOI: 10.1038/S41598-018-31192-0  0.456
2018 Chang ACY, Chang ACH, Kirillova A, Sasagawa K, Su W, Weber G, Lin J, Termglinchan V, Karakikes I, Seeger T, Dainis AM, Hinson JT, Seidman J, Seidman CE, Day JW, ... ... Wu JC, et al. Telomere shortening is a hallmark of genetic cardiomyopathies. Proceedings of the National Academy of Sciences of the United States of America. PMID 30150400 DOI: 10.1073/Pnas.1714538115  0.816
2018 Lam CK, Wu JC. Disease modelling and drug discovery for hypertrophic cardiomyopathy using pluripotent stem cells: how far have we come? European Heart Journal. PMID 30010924 DOI: 10.1093/Eurheartj/Ehy388  0.735
2018 Paik DT, Tian L, Lee J, Sayed N, Chen IY, Rhee S, Rhee JW, Kim Y, Wirka RC, Buikema JW, Wu SM, Red-Horse K, Quertermous T, Wu JC. Large-Scale Single-Cell RNA-Seq Reveals Molecular Signatures of Heterogeneous Populations of Human Induced Pluripotent Stem Cell-Derived Endothelial Cells. Circulation Research. PMID 29986945 DOI: 10.1161/Circresaha.118.312913  0.837
2018 Garg P, Garg V, Shrestha R, Sanguinetti MC, Kamp TJ, Wu JC. Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes as Models for Cardiac Channelopathies: A Primer for Non-Electrophysiologists. Circulation Research. 123: 224-243. PMID 29976690 DOI: 10.1161/Circresaha.118.311209  0.44
2018 Garg P, Oikonomopoulos A, Chen H, Li Y, Lam CK, Sallam K, Perez M, Lux RL, Sanguinetti MC, Wu JC. Genome Editing of Induced Pluripotent Stem Cells to Decipher Cardiac Channelopathy Variant. Journal of the American College of Cardiology. 72: 62-75. PMID 29957233 DOI: 10.1016/J.Jacc.2018.04.041  0.807
2018 Ma N, Zhang J, Itzhaki I, Zhang SL, Chen H, Haddad F, Kitani T, Wilson KD, Tian L, Shrestha R, Wu H, Lam CK, Sayed N, Wu JC. Determining the Pathogenicity of a Genomic Variant of Uncertain Significance Using CRISPR/Cas9 and Human-Induced Pluripotent Stem Cells. Circulation. PMID 29914921 DOI: 10.1161/Circulationaha.117.032273  0.811
2018 Wnorowski A, Yang H, Wu JC. Progress, obstacles, and limitations in the use of stem cells in organ-on-a-chip models. Advanced Drug Delivery Reviews. PMID 29885330 DOI: 10.1016/J.Addr.2018.06.001  0.738
2018 Adam M, Kooreman N, Jagger A, Wagenhaeuser MU, Mehrkens D, Wang Y, Kayama Y, Toyama K, Raaz U, Schellinger IN, Maegdefessel L, Spin JM, Hamming JF, Quax PHA, Baldus S, ... Wu JC, et al. Systemic Upregulation of IL-10 (Interleukin-10) Using a Nonimmunogenic Vector Reduces Growth and Rate of Dissecting Abdominal Aortic Aneurysm. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 29880489 DOI: 10.1161/Atvbaha.117.310672  0.499
2018 Musunuru K, Sheikh F, Gupta RM, Houser SR, Maher KO, Milan DJ, Terzic A, Wu JC. Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling and Precision Medicine: A Scientific Statement From the American Heart Association. Circulation. Genomic and Precision Medicine. 11: e000043. PMID 29874173 DOI: 10.1161/HCG.0000000000000043  0.379
2018 Argenziano M, Lambers E, Hong L, Sridhar A, Zhang M, Chalazan B, Menon A, Savio-Galimberti E, Wu JC, Rehman J, Darbar D. Electrophysiologic Characterization of Calcium Handling in Human Induced Pluripotent Stem Cell-Derived Atrial Cardiomyocytes. Stem Cell Reports. PMID 29731429 DOI: 10.1016/J.Stemcr.2018.04.005  0.396
2018 Lee AS, Inayathullah M, Lijkwan MA, Zhao X, Sun W, Park S, Hong WX, Parekh MB, Malkovskiy AV, Lau E, Qin X, Pothineni VR, Sanchez-Freire V, Zhang WY, Kooreman NG, ... ... Wu JC, et al. Prolonged survival of transplanted stem cells after ischaemic injury via the slow release of pro-survival peptides from a collagen matrix. Nature Biomedical Engineering. 2: 104-113. PMID 29721363 DOI: 10.1038/S41551-018-0191-4  0.817
2018 Millard D, Dang Q, Shi H, Zhang X, Strock C, Kraushaar U, Zeng H, Levesque P, Lu HR, Guillon JM, Wu JC, Li Y, Luerman G, Anson B, Guo L, et al. Cross-Site Reliability of Human Induced Pluripotent Stem-Cell Derived Cardiomyocyte Based Safety Assays using Microelectrode Arrays: Results from a Blinded CiPA Pilot Study. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 29718449 DOI: 10.1093/Toxsci/Kfy110  0.381
2018 Sharma A, Zhang Y, Buikema JW, Serpooshan V, Chirikian O, Kosaric N, Churko JM, Dzilic E, Shieh A, Burridge PW, Wu JC, Wu SM. Stage-specific Effects of Bioactive Lipids on Human iPSC Cardiac Differentiation and Cardiomyocyte Proliferation. Scientific Reports. 8: 6618. PMID 29700394 DOI: 10.1038/S41598-018-24954-3  0.806
2018 Lau E, Wu JC. Omics, Big Data, and Precision Medicine in Cardiovascular Sciences. Circulation Research. 122: 1165-1168. PMID 29700063 DOI: 10.1161/Circresaha.118.313161  0.595
2018 Oikonomopoulos A, Kitani T, Wu JC. Pluripotent Stem Cell-Derived Cardiomyocytes as a Platform for Cell Therapy Applications: Progress and Hurdles for Clinical Translation. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 29699941 DOI: 10.1016/J.Ymthe.2018.02.026  0.79
2018 Cheng H, Dharmadhikari AV, Varland S, Ma N, Domingo D, Kleyner R, Rope AF, Yoon M, Stray-Pedersen A, Posey JE, Crews SR, Eldomery MK, Akdemir ZC, Lewis AM, Sutton VR, ... ... Wu JC, et al. Truncating Variants in NAA15 Are Associated with Variable Levels of Intellectual Disability, Autism Spectrum Disorder, and Congenital Anomalies. American Journal of Human Genetics. PMID 29656860 DOI: 10.1016/J.Ajhg.2018.03.004  0.304
2018 Zhang JZ, Guo H, Wu JC. Applications of genetically engineered human pluripotent stem cell reporters in cardiac stem cell biology. Current Opinion in Biotechnology. 52: 66-73. PMID 29579626 DOI: 10.1016/J.Copbio.2018.03.002  0.49
2018 Nishiga M, Guo H, Wu JC. Induced pluripotent stem cells as a biopharmaceutical factory for extracellular vesicles. European Heart Journal. PMID 29547885 DOI: 10.1093/Eurheartj/Ehy097  0.448
2018 Liu C, Oikonomopoulos A, Sayed N, Wu JC. Modeling human diseases with induced pluripotent stem cells: from 2D to 3D and beyond. Development (Cambridge, England). 145. PMID 29519889 DOI: 10.1242/Dev.156166  0.657
2018 Lee J, Shao NY, Paik DT, Wu H, Guo H, Termglinchan V, Churko JM, Kim Y, Kitani T, Zhao MT, Zhang Y, Wilson KD, Karakikes I, Snyder MP, Wu JC. SETD7 Drives Cardiac Lineage Commitment through Stage-Specific Transcriptional Activation. Cell Stem Cell. 22: 428-444.e5. PMID 29499155 DOI: 10.1016/J.Stem.2018.02.005  0.8
2018 Kooreman NG, Kim Y, de Almeida PE, Termglinchan V, Diecke S, Shao NY, Wei TT, Yi H, Dey D, Nelakanti R, Brouwer TP, Paik DT, Sagiv-Barfi I, Han A, Quax PHA, ... ... Wu JC, et al. Autologous iPSC-Based Vaccines Elicit Anti-tumor Responses In Vivo. Cell Stem Cell. PMID 29456158 DOI: 10.1016/J.Stem.2018.01.016  0.655
2018 Ong SG, Lee WH, Zhou Y, Wu JC. Mining Exosomal MicroRNAs from Human-Induced Pluripotent Stem Cells-Derived Cardiomyocytes for Cardiac Regeneration. Methods in Molecular Biology (Clifton, N.J.). 1733: 127-136. PMID 29435928 DOI: 10.1007/978-1-4939-7601-0_10  0.77
2018 Zhao X, Chen H, Xiao D, Yang H, Itzhaki I, Qin X, Chour T, Aguirre A, Lehmann K, Kim Y, Shukla P, Holmström A, Zhang JZ, Zhuge Y, Ndoye BC, ... ... Wu JC, et al. Comparison of Non-human Primate versus Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Treatment of Myocardial Infarction. Stem Cell Reports. PMID 29398480 DOI: 10.1016/J.Stemcr.2018.01.002  0.764
2018 Stack JP, Moslehi J, Sayed N, Wu JC. Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it? European Heart Journal. PMID 29377985 DOI: 10.1093/Eurheartj/Ehx811  0.669
2018 Rhee S, Chung JI, King DA, D'amato G, Paik DT, Duan A, Chang A, Nagelberg D, Sharma B, Jeong Y, Diehn M, Wu JC, Morrison AJ, Red-Horse K. Endothelial deletion of Ino80 disrupts coronary angiogenesis and causes congenital heart disease. Nature Communications. 9: 368. PMID 29371594 DOI: 10.1038/S41467-017-02796-3  0.456
2018 Rhee JW, Wu JC. Cardiac Cell Cycle Activation as a Strategy to Improve iPSC-Derived Cardiomyocyte Therapy. Circulation Research. 122: 14-16. PMID 29301838 DOI: 10.1161/Circresaha.117.312287  0.501
2018 Paik DT, Tian L, Lee J, Sayed N, Mishra R, Wu JC. Abstract 472: Large-Scale Single-Cell RNA-Seq Identifies Heterogeneous Populations of Human Primary and Induced Pluripotent Stem Cell-Derived Endothelial Cells Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.472  0.796
2018 Wnorowski A, Sharma A, Chen H, Wu H, Shao N, Churko JM, Matsa E, Countryman S, Rubins K, Wu SM, Lee PH, Wu JC. Abstract 379: Effects of Microgravity on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.379  0.818
2018 Lau E, Shrestha R, Thomas CT, Williams DR, Wu JC. Abstract 315: Time-resolved Expression of Membrane-targeted Proteins During Ipsc-cardiomyocyte Differentiation Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.315  0.599
2018 Wu H, Yang H, Rhee J, Zhang J, Lam CK, Sallam K, Chang AC, Ma N, Blau H, Bers D, Wu J. Abstract 243: Modeling of Diastolic Dysfunction in Induced Pluripotent Stem Cell-derived Cardiomyocytes From Hypertrophic Cardiomyopathy Patients Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.243  0.818
2018 Zhang JZ, Termglinchan V, Itzhaki I, Wang V, Shao N, Chang A, Ma N, Liu C, Kitani T, Sayed N, Wu H, Lam C, Blau H, Wu J. Abstract 217: TBX5 Clover2 /NKX2-5 TagRFP hiPSCs for Simultaneously Isolating Lineage-Specific Cardiovascular Cells Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.217  0.808
2018 Sayed N, Liu C, Himmati F, Zhang J, Khanamiri S, Chen H, Moonen J, Wnorowski A, Matsa E, Cheng L, Sallam K, Rabinovitch M, Wu JC. Abstract 209: Downregulation of KLF2 in the Endothelium Contributes to the Pathogenesis in LMNA-related Dilated Cardiomyopathy Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.209  0.755
2018 Sass G, Madigan R, Bozzi A, Sayed N, Wu J, Stevens D. 1357. A Combination of Itraconazole and Amiodarone Is Highly Effective Against Trypanosoma cruzi Infection of Human Stem Cell-Derived Cardiomyocytes Open Forum Infectious Diseases. 5. DOI: 10.1093/Ofid/Ofy210.1188  0.827
2018 Gara E, Ong SG, Winkler J, Zlabinger K, Lukovic D, Jakab A, Merkely B, Wu JC, Gyongyosi M, Pavo N. 240Mesenchymal stem cells transfected with minicircle-HIF-1a decreases LV adverse remodelling via release of cardioprotective miRNAs and pro-angiogenic factors Cardiovascular Research. 114: S62-S62. DOI: 10.1093/Cvr/Cvy060.168  0.639
2018 Bouajila S, Moneghetti K, Kobayashi Y, Gomari FA, Abbasi F, Davis MM, Wu JC, Kuznetsova T, Sayed N, Haddad F. Immune Profile Of Healthy Cardiovascular Aging: Insights From A Population-Based Study And Network Modeling Journal of the American College of Cardiology. 71. DOI: 10.1016/S0735-1097(18)32198-3  0.589
2018 Kort E, Sayed N, Wu J, Jovinge S. REVERSING LMNA MUTATION PHENOTYPE IN CARDIOMYOCYTES WITH OLMESARTAN: CONNECTING MONOGENIC DISEASE TO DRUGS VIA TRANSCRIPTIONAL SIGNATURES Journal of the American College of Cardiology. 71: A897. DOI: 10.1016/S0735-1097(18)31438-4  0.635
2018 Lam CK, Ma N, Rhee J, Kitani T, Zhang J, Shrestha R, Wu H, Wu JC. Identifying the Novel Role of a Presenilin-2 Mutation in Arrhythmogenicity using Patient Specific Induced Pluripotent Stem Cells Derived Cardiomyocytes Journal of Molecular and Cellular Cardiology. 124: 109. DOI: 10.1016/J.Yjmcc.2018.07.080  0.832
2018 Kim K, Wang L, Sequeira V, Wu JC, Knollmann BC. Comparable Calcium Handling and Contractility in Human IPSC Cardiomyocyte Models of Three Different Hypertrophic Cardiomyopathy-Linked Mutations Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.3352  0.313
2018 Kernik DC, Morotti S, Duff HJ, Kurokawa J, Jalife J, Wu JC, Grandi E, Colleen CE. A Computational Analysis of Inter-Subject Variability in Induced Pluripotent Stem Cell-Derived Cardiomyocytes Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.2602  0.412
2017 Lin ZC, McGuire AF, Burridge PW, Matsa E, Lou HY, Wu JC, Cui B. Accurate nanoelectrode recording of human pluripotent stem cell-derived cardiomyocytes for assaying drugs and modeling disease. Microsystems & Nanoengineering. 3: 16080. PMID 31057850 DOI: 10.1038/Micronano.2016.80  0.7
2017 Churko JM, Lee J, Ameen M, Gu M, Venkatasubramanian M, Diecke S, Sallam K, Im H, Wang G, Gold JD, Salomonis N, Snyder MP, Wu JC. Transcriptomic and epigenomic differences in human induced pluripotent stem cells generated from six reprogramming methods. Nature Biomedical Engineering. 1: 826-837. PMID 30263871 DOI: 10.1038/S41551-017-0141-6  0.829
2017 Paik DT, Wu JC. Simply derived epicardial cells. Nature Biomedical Engineering. 1. PMID 29354320 DOI: 10.1038/S41551-016-0015  0.458
2017 Zhao MT, Chen H, Liu Q, Shao NY, Sayed N, Wo HT, Zhang JZ, Ong SG, Liu C, Kim Y, Yang H, Chour T, Ma H, Gutierrez NM, Karakikes I, ... ... Wu JC, et al. Molecular and functional resemblance of differentiated cells derived from isogenic human iPSCs and SCNT-derived ESCs. Proceedings of the National Academy of Sciences of the United States of America. PMID 29203658 DOI: 10.1073/Pnas.1708991114  0.842
2017 Sayed N, Wu JC. Towards Cardio-Precision medicine. European Heart Journal. 38: 1014-1016. PMID 29121213 DOI: 10.1093/Eurheartj/Ehx089  0.589
2017 Abilez OJ, Tzatzalos E, Yang H, Zhao MT, Jung G, Zöllner AM, Tiburcy M, Riegler J, Matsa E, Shukla P, Zhuge Y, Chour T, Chen VC, Burridge PW, Karakikes I, ... ... Wu JC, et al. Passive Stretch Induces Structural and Functional Maturation of Engineered Heart Muscle as Predicted by Computational Modeling. Stem Cells (Dayton, Ohio). PMID 29086457 DOI: 10.1002/Stem.2732  0.816
2017 Zhao M, Shao NY, Hu S, Ma N, Srinivasan R, Jahanbani F, Lee J, Zhang SL, Snyder MP, Wu JC. Cell Type-Specific Chromatin Signatures Underline Regulatory DNA Elements in Human Induced Pluripotent Stem Cells and Somatic Cells. Circulation Research. PMID 29030344 DOI: 10.1161/Circresaha.117.311367  0.821
2017 Magdy T, Schuldt AJT, Wu JC, Bernstein D, Burridge PW. Human Induced Pluripotent Stem Cell (hiPSC)-Derived Cells to Assess Drug Cardiotoxicity: Opportunities and Problems. Annual Review of Pharmacology and Toxicology. PMID 28992430 DOI: 10.1146/Annurev-Pharmtox-010617-053110  0.661
2017 Mahmoudi M, Yu M, Serpooshan V, Wu JC, Langer R, Lee RT, Karp JM, Farokhzad OC. Multiscale technologies for treatment of ischemic cardiomyopathy. Nature Nanotechnology. 12: 845-855. PMID 28875984 DOI: 10.1038/Nnano.2017.167  0.353
2017 Kooreman NG, de Almeida PE, Stack JP, Nelakanti RV, Diecke S, Shao NY, Swijnenburg RJ, Sanchez-Freire V, Matsa E, Liu C, Connolly AJ, Hamming JF, Quax PHA, Brehm MA, Greiner DL, ... ... Wu JC, et al. Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics. Cell Reports. 20: 1978-1990. PMID 28834758 DOI: 10.1016/J.Celrep.2017.08.003  0.73
2017 Zhang J, Li H, Trounson A, Wu JC, Nioi P. Combining hiPSCs and Human Genetics: Major Applications in Drug Development. Cell Stem Cell. 21: 161-165. PMID 28777942 DOI: 10.1016/J.Stem.2017.07.012  0.312
2017 Chamberland S, Yang HH, Pan MM, Evans SW, Guan S, Chavarha M, Yang Y, Salesse C, Wu H, Wu JC, Clandinin TR, Toth K, Lin MZ, St-Pierre F. Fast two-photon imaging of subcellular voltage dynamics in neuronal tissue with genetically encoded indicators. Elife. 6. PMID 28749338 DOI: 10.7554/Elife.25690  0.593
2017 Wanjare M, Hou L, Nakayama KH, Kim JJ, Mezak NP, Abilez OJ, Tzatzalos E, Wu JC, Huang NF. Anisotropic microfibrous scaffolds enhance the organization and function of cardiomyocytes derived from induced pluripotent stem cells. Biomaterials Science. PMID 28715029 DOI: 10.1039/C7Bm00323D  0.376
2017 Lee WH, Chen W, Shao NY, Xiao D, Qin X, Baker N, Bae HRM, Shukla P, Wu H, Kodo K, Ong SG, Wu JC. Comparison of Non-Coding RNAs in Exosomes and Functional Efficacy of Human Embryonic Stem Cell- Versus Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Stem Cells (Dayton, Ohio). PMID 28710827 DOI: 10.1002/Stem.2669  0.843
2017 Liu Q, Jiang C, Xu J, Zhao M, Van Bortle K, Cheng X, Wang G, Chang HY, Wu JC, Snyder MP. Genome-Wide Temporal Profiling of Transcriptome and Open-Chromatin of Early Cardiomyocyte Differentiation Derived From hiPSCs and hESCs. Circulation Research. PMID 28663367 DOI: 10.1161/Circresaha.116.310456  0.441
2017 Li Y, Sallam K, Schwartz PJ, Wu JC. Patient-Specific Induced Pluripotent Stem Cell-Based Disease Model for Pathogenesis Studies and Clinical Pharmacotherapy. Circulation. Arrhythmia and Electrophysiology. 10. PMID 28630175 DOI: 10.1161/Circep.117.005398  0.708
2017 Lee AS, Tang C, Hong WX, Park S, Bazalova M, Nelson G, Sanchez-Freire V, Bakerman I, Zhang W, Neofytou E, Connolly AJ, Chan CK, Graves EE, Weissman IL, Nguyen PK, ... Wu JC, et al. External Beam Radiation Therapy for the Treatment of Human Pluripotent Stem Cell-Derived Teratomas. Stem Cells (Dayton, Ohio). PMID 28600830 DOI: 10.1002/Stem.2653  0.686
2017 Gowrishankar G, Hardy J, Wardak M, Namavari M, Reeves R, Neofytou E, Srinivasan A, Wu J, Contag C, Gambhir S. Specific Imaging of Bacterial Infection using 6'' -(18)F-Fluoromaltotriose: A Second Generation PET Tracer Targeting the Maltodextrin Transporter in Bacteria. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 28490473 DOI: 10.2967/Jnumed.117.191452  0.39
2017 Wnorowski A, Wu JC. 3-Dimensionally Printed, Native-Like Scaffolds for Myocardial Tissue Engineering. Circulation Research. 120: 1224-1226. PMID 28408446 DOI: 10.1161/Circresaha.117.310862  0.338
2017 Lee S, Serpooshan V, Tong X, Venkatraman S, Lee M, Lee J, Chirikian O, Wu JC, Wu SM, Yang F. Contractile force generation by 3D hiPSC-derived cardiac tissues is enhanced by rapid establishment of cellular interconnection in matrix with muscle-mimicking stiffness. Biomaterials. 131: 111-120. PMID 28384492 DOI: 10.1016/J.Biomaterials.2017.03.039  0.68
2017 Serpooshan V, Chen P, Wu H, Lee S, Sharma A, Hu DA, Venkatraman S, Ganesan AV, Usta OB, Yarmush M, Yang F, Wu JC, Demirci U, Wu SM. Bioacoustic-enabled patterning of human iPSC-derived cardiomyocytes into 3D cardiac tissue. Biomaterials. 131: 47-57. PMID 28376365 DOI: 10.1016/J.Biomaterials.2017.03.037  0.7
2017 Chuang W, Sharma A, Shukla P, Li G, Mall M, Rajarajan K, Abilez OJ, Hamaguchi R, Wu JC, Wernig M, Wu SM. Partial Reprogramming of Pluripotent Stem Cell-Derived Cardiomyocytes into Neurons. Scientific Reports. 7: 44840. PMID 28327614 DOI: 10.1038/Srep44840  0.349
2017 Seeger T, Porteus M, Wu JC. Genome Editing in Cardiovascular Biology. Circulation Research. 120: 778-780. PMID 28254802 DOI: 10.1161/Circresaha.116.310197  0.696
2017 Karakikes I, Termglinchan V, Cepeda DA, Lee J, Diecke S, Hendel A, Itzhaki I, Ameen M, Shrestha R, Wu H, Ma N, Shao NY, Seeger T, Woo NA, Wilson KD, ... ... Wu JC, et al. A Comprehensive TALEN-Based Knockout Library for Generating Human Induced Pluripotent Stem Cell-Based Models for Cardiovascular Diseases. Circulation Research. PMID 28246128 DOI: 10.1161/Circresaha.116.309948  0.831
2017 Cao Y, Hjort M, Chen H, Birey F, Leal-Ortiz SA, Han CM, Santiago JG, Paşca SP, Wu JC, Melosh NA. Nondestructive nanostraw intracellular sampling for longitudinal cell monitoring. Proceedings of the National Academy of Sciences of the United States of America. PMID 28223521 DOI: 10.1073/Pnas.1615375114  0.404
2017 Sharma A, Burridge PW, McKeithan WL, Serrano R, Shukla P, Sayed N, Churko JM, Kitani T, Wu H, Holmström A, Matsa E, Zhang Y, Kumar A, Fan AC, Del Álamo JC, ... ... Wu JC, et al. High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells. Science Translational Medicine. 9. PMID 28202772 DOI: 10.1126/Scitranslmed.Aaf2584  0.815
2017 Shukla P, Wu JC. Cardiac subtype characterization using all-optical action potential imaging. European Heart Journal. 38: 302-304. PMID 28182229 DOI: 10.1093/Eurheartj/Ehw380  0.509
2017 Tiburcy M, Hudson JE, Balfanz P, Schlick SF, Meyer T, Chang Liao ML, Levent E, Raad F, Zeidler S, Wingender E, Riegler J, Wang M, Gold JD, Kehat I, Wettwer E, ... ... Wu JC, et al. Defined Engineered Human Myocardium with Advanced Maturation for Applications in Heart Failure Modelling and Repair. Circulation. PMID 28167635 DOI: 10.1161/Circulationaha.116.024145  0.411
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