Year |
Citation |
Score |
2020 |
Fathzadeh M, Li J, Rao A, Cook N, Chennamsetty I, Seldin M, Zhou X, Sangwung P, Gloudemans MJ, Keller M, Attie A, Yang J, Wabitsch M, Carcamo-Orive I, Tada Y, ... ... Knowles JW, et al. FAM13A affects body fat distribution and adipocyte function. Nature Communications. 11: 1465. PMID 32193374 DOI: 10.1038/S41467-020-15291-Z |
0.332 |
|
2019 |
Cook NL, Pjanic M, Emmerich AG, Rao AS, Hetty S, Knowles JW, Quertermous T, Castillejo-López C, Ingelsson E. CRISPR-Cas9-mediated knockout of SPRY2 in human hepatocytes leads to increased glucose uptake and lipid droplet accumulation. Bmc Endocrine Disorders. 19: 115. PMID 31664995 DOI: 10.1186/S12902-019-0442-8 |
0.316 |
|
2019 |
Rao AS, Knowles JW. Polygenic risk scores in coronary artery disease. Current Opinion in Cardiology. PMID 30994529 DOI: 10.1097/Hco.0000000000000629 |
0.331 |
|
2019 |
Sarraju A, Knowles JW. Genetic Testing and Risk Scores: Impact on Familial Hypercholesterolemia. Frontiers in Cardiovascular Medicine. 6: 5. PMID 30761309 DOI: 10.3389/Fcvm.2019.00005 |
0.391 |
|
2018 |
Sturm AC, Knowles JW, Gidding SS, Ahmad ZS, Ahmed CD, Ballantyne CM, Baum SJ, Bourbon M, Carrié A, Cuchel M, de Ferranti SD, Defesche JC, Freiberger T, Hershberger RE, Hovingh GK, et al. Clinical Genetic Testing for Familial Hypercholesterolemia: JACC Scientific Expert Panel. Journal of the American College of Cardiology. 72: 662-680. PMID 30071997 DOI: 10.1016/J.Jacc.2018.05.044 |
0.359 |
|
2018 |
Rodriguez F, Knowles JW, Maron DJ, Virani SS, Heidenreich PA. Frequency of Statin Use in Patients With Low-Density Lipoprotein Cholesterol ≥190 mg/dl from the Veterans Affairs Health System. The American Journal of Cardiology. PMID 30055758 DOI: 10.1016/J.Amjcard.2018.05.008 |
0.304 |
|
2018 |
Knowles JW, Ashley EA. Cardiovascular disease: The rise of the genetic risk score. Plos Medicine. 15: e1002546. PMID 29601582 DOI: 10.1371/Journal.Pmed.1002546 |
0.327 |
|
2017 |
Helle EIT, Biegley P, Knowles JW, Leader JB, Pendergrass S, Yang W, Reaven GR, Shaw GM, Ritchie M, Priest JR. First Trimester Plasma Glucose Values in Women without Diabetes are Associated with Risk for Congenital Heart Disease in Offspring. The Journal of Pediatrics. PMID 29254757 DOI: 10.1016/J.Jpeds.2017.10.046 |
0.312 |
|
2017 |
Knowles JW, Zarafshar S, Pavlovic A, Goldstein BA, Tsai S, Li J, McConnell MV, Absher D, Ashley EA, Kiernan M, Ioannidis JPA, Assimes TL. Impact of a Genetic Risk Score for Coronary Artery Disease on Reducing Cardiovascular Risk: A Pilot Randomized Controlled Study. Frontiers in Cardiovascular Medicine. 4: 53. PMID 28856136 DOI: 10.3389/Fcvm.2017.00053 |
0.336 |
|
2017 |
Reaven GM, Knowles JW, Leonard D, Barlow CE, Willis BL, Haskell WL, Maron DJ. Relationship between simple markers of insulin resistance and coronary artery calcification. Journal of Clinical Lipidology. PMID 28652190 DOI: 10.1016/J.Jacl.2017.05.013 |
0.308 |
|
2017 |
Ingelsson E, Knowles JW. Leveraging Human Genetics to Understand the Relation of LDL Cholesterol with Type 2 Diabetes. Clinical Chemistry. PMID 28515096 DOI: 10.1373/Clinchem.2016.268565 |
0.384 |
|
2017 |
Knowles JW, Howard WB, Karayan L, Baum SJ, Wilemon KA, Ballantyne CM, Myers KD. Access to Non-Statin Lipid Lowering Therapies in Patients at High-Risk of Atherosclerotic Cardiovascular Disease. Circulation. PMID 28446516 DOI: 10.1161/Circulationaha.117.027705 |
0.316 |
|
2017 |
Rodriguez F, Knowles J, Maron D, Virani S, Heidenreich P. Predictors Of Statin Use For Patients With Ldl Cholesterol Above 190Mg/Dl: Insights From The Veterans Affairs Health Care System Journal of the American College of Cardiology. 69: 1693. DOI: 10.1016/S0735-1097(17)35082-9 |
0.31 |
|
2016 |
Rodriguez F, Lin S, Maron DJ, Knowles JW, Virani SS, Heidenreich PA. Use of high-intensity statins for patients with atherosclerotic cardiovascular disease in the Veterans Affairs Health System: Practice impact of the new cholesterol guidelines. American Heart Journal. 182: 97-102. PMID 27914506 DOI: 10.1016/J.Ahj.2016.09.007 |
0.312 |
|
2016 |
Abbasi F, Kohli P, Reaven GM, Knowles JW. Hypertriglyceridemia: A simple approach to identify insulin resistance and enhanced cardio-metabolic risk in patients with prediabetes. Diabetes Research and Clinical Practice. 120: 156-161. PMID 27565692 DOI: 10.1016/J.Diabres.2016.07.024 |
0.334 |
|
2016 |
Rodriguez F, Knowles JW. Enough Evidence, Time to Act! Circulation. 134: 20-3. PMID 27358433 DOI: 10.1161/Circulationaha.116.023010 |
0.37 |
|
2016 |
Caleshu C, Kasparian NA, Edwards KS, Yeates L, Semsarian C, Perez M, Ashley E, Turner CJ, Knowles JW, Ingles J. Interdisciplinary psychosocial care for families with inherited cardiovascular diseases. Trends in Cardiovascular Medicine. PMID 27256036 DOI: 10.1016/J.Tcm.2016.04.010 |
0.325 |
|
2016 |
Sarraju A, Kim SH, Knowles JW. Cardiometabolic Effects of Glucagon-Like Peptide-1 Agonists. Current Atherosclerosis Reports. 18: 7. PMID 26782825 DOI: 10.1007/S11883-016-0558-5 |
0.342 |
|
2016 |
Pariani MJ, Knowles JW. Integration of Clinical Genetic Testing in Cardiovascular Care Current Genetic Medicine Reports. 4: 107-118. DOI: 10.1007/S40142-016-0094-1 |
0.337 |
|
2015 |
Gidding SS, Ann Champagne M, de Ferranti SD, Defesche J, Ito MK, Knowles JW, McCrindle B, Raal F, Rader D, Santos RD, Lopes-Virella M, Watts GF, Wierzbicki AS. The Agenda for Familial Hypercholesterolemia: A Scientific Statement From the American Heart Association. Circulation. PMID 26510694 DOI: 10.1161/Cir.0000000000000297 |
0.347 |
|
2015 |
Priest JR, Yang W, Reaven G, Knowles JW, Shaw GM. Maternal Midpregnancy Glucose Levels and Risk of Congenital Heart Disease in Offspring. Jama Pediatrics. 1-5. PMID 26457543 DOI: 10.1001/Jamapediatrics.2015.2831 |
0.327 |
|
2015 |
Knowles JW, Stone NJ, Ballantyne CM. Familial Hypercholesterolemia and the 2013 American College of Cardiology/American Heart Association Guidelines: Myths, Oversimplification, and Misinterpretation Versus Facts. The American Journal of Cardiology. 116: 481-4. PMID 26043952 DOI: 10.1016/J.Amjcard.2015.04.062 |
0.352 |
|
2015 |
Fall T, Xie W, Poon W, Yaghootkar H, Mägi R, Knowles JW, Lyssenko V, Weedon M, Frayling TM, Ingelsson E. Using Genetic Variants to Assess the Relationship Between Circulating Lipids and Type 2 Diabetes. Diabetes. 64: 2676-84. PMID 25948681 DOI: 10.2337/Db14-1710 |
0.348 |
|
2015 |
Knowles JW, Xie W, Zhang Z, Chennemsetty I, Assimes TL, Paananen J, Hansson O, Pankow J, Goodarzi MO, Carcamo-Orive I, Morris AP, Chen YD, Mäkinen VP, Ganna A, Mahajan A, et al. Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene. The Journal of Clinical Investigation. 125: 1739-51. PMID 25798622 DOI: 10.1172/Jci74692 |
0.322 |
|
2015 |
Rodriguez F, Knowles JW. PCSK9 inhibition: current concepts and lessons from human genetics. Current Atherosclerosis Reports. 17: 487. PMID 25637042 DOI: 10.1007/S11883-015-0487-8 |
0.318 |
|
2015 |
Kohli P, Waters D, Fayyad R, Laskey R, DeMicco D, Knowles J, Reaven G. RISK OF NEW-ONSET DIABETES FROM STATIN THERAPY INCREASES WITH INCREASING BASELINE TRIGLYCERIDES: DATA FROM TNT Journal of the American College of Cardiology. 65: A1441. DOI: 10.1016/S0735-1097(15)61441-3 |
0.324 |
|
2015 |
O’Brien EC, DeGoma E, Moriarty P, Linton MF, Shapiro M, Duell B, Ballantyne C, Neal W, Ahmad Z, Duffy D, Hudgins L, Hemphill L, Underberg J, Watson K, Gidding S, ... ... Knowles J, et al. INITIAL RESULTS FROM THE CASCADE-FH REGISTRY: CASCADE SCREENING FOR AWARENESS AND DETECTION OF FAMILIAL HYPERCHOLESTEROLEMIA Journal of the American College of Cardiology. 65: A1372. DOI: 10.1016/S0735-1097(15)61372-9 |
0.348 |
|
2014 |
Knowles JW, O'Brien EC, Greendale K, Wilemon K, Genest J, Sperling LS, Neal WA, Rader DJ, Khoury MJ. Reducing the burden of disease and death from familial hypercholesterolemia: a call to action. American Heart Journal. 168: 807-11. PMID 25458642 DOI: 10.1016/J.Ahj.2014.09.001 |
0.339 |
|
2014 |
Goldstein BA, Knowles JW, Salfati E, Ioannidis JP, Assimes TL. Simple, standardized incorporation of genetic risk into non-genetic risk prediction tools for complex traits: coronary heart disease as an example. Frontiers in Genetics. 5: 254. PMID 25136350 DOI: 10.3389/Fgene.2014.00254 |
0.347 |
|
2014 |
Yaghootkar H, Scott RA, White CC, Zhang W, Speliotes E, Munroe PB, Ehret GB, Bis JC, Fox CS, Walker M, Borecki IB, Knowles JW, Yerges-Armstrong L, Ohlsson C, Perry JR, et al. Genetic evidence for a normal-weight "metabolically obese" phenotype linking insulin resistance, hypertension, coronary artery disease, and type 2 diabetes. Diabetes. 63: 4369-77. PMID 25048195 DOI: 10.2337/Db14-0318 |
0.359 |
|
2014 |
O'Brien EC, Roe MT, Fraulo ES, Peterson ED, Ballantyne CM, Genest J, Gidding SS, Hammond E, Hemphill LC, Hudgins LC, Kindt I, Moriarty PM, Ross J, Underberg JA, Watson K, ... ... Knowles JW, et al. Rationale and design of the familial hypercholesterolemia foundation CAscade SCreening for Awareness and DEtection of Familial Hypercholesterolemia registry. American Heart Journal. 167: 342-349.e17. PMID 24576518 DOI: 10.1016/J.Ahj.2013.12.008 |
0.335 |
|
2014 |
Dimas AS, Lagou V, Barker A, Knowles JW, Mägi R, Hivert MF, Benazzo A, Rybin D, Jackson AU, Stringham HM, Song C, Fischer-Rosinsky A, Boesgaard TW, Grarup N, Abbasi FA, et al. Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity. Diabetes. 63: 2158-71. PMID 24296717 DOI: 10.2337/Db13-0949 |
0.332 |
|
2013 |
Yaghootkar H, Lamina C, Scott RA, Dastani Z, Hivert MF, Warren LL, Stancáková A, Buxbaum SG, Lyytikäinen LP, Henneman P, Wu Y, Cheung CY, Pankow JS, Jackson AU, Gustafsson S, ... ... Knowles JW, et al. Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes. Diabetes. 62: 3589-98. PMID 23835345 DOI: 10.2337/Db13-0128 |
0.322 |
|
2013 |
Coram MA, Duan Q, Hoffmann TJ, Thornton T, Knowles JW, Johnson NA, Ochs-Balcom HM, Donlon TA, Martin LW, Eaton CB, Robinson JG, Risch NJ, Zhu X, Kooperberg C, Li Y, et al. Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations. American Journal of Human Genetics. 92: 904-16. PMID 23726366 DOI: 10.1016/J.Ajhg.2013.04.025 |
0.328 |
|
2013 |
den Hoed M, Eijgelsheim M, Esko T, Brundel BJ, Peal DS, Evans DM, Nolte IM, Segrè AV, Holm H, Handsaker RE, Westra HJ, Johnson T, Isaacs A, Yang J, Lundby A, ... ... Knowles JW, et al. Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nature Genetics. 45: 621-31. PMID 23583979 DOI: 10.1038/Ng.2610 |
0.319 |
|
2013 |
Xie W, Wood AR, Lyssenko V, Weedon MN, Knowles JW, Alkayyali S, Assimes TL, Quertermous T, Abbasi F, Paananen J, Häring H, Hansen T, Pedersen O, Smith U, Laakso M, et al. Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes. Diabetes. 62: 2141-50. PMID 23378610 DOI: 10.2337/Db12-0876 |
0.33 |
|
2013 |
Deloukas P, Kanoni S, Willenborg C, Farrall M, Assimes TL, Thompson JR, Ingelsson E, Saleheen D, Erdmann J, Goldstein BA, Stirrups K, König IR, Cazier JB, Johansson A, ... ... Knowles JW, et al. Large-scale association analysis identifies new risk loci for coronary artery disease. Nature Genetics. 45: 25-33. PMID 23202125 DOI: 10.1038/Ng.2480 |
0.363 |
|
2012 |
Pan S, Knowles JW. Exploring predisposition and treatment response--the promise of genomics. Progress in Cardiovascular Diseases. 55: 56-63. PMID 22824110 DOI: 10.1016/J.Pcad.2012.04.006 |
0.323 |
|
2012 |
Knowles JW, Assimes TL, Kiernan M, Pavlovic A, Goldstein BA, Yank V, McConnell MV, Absher D, Bustamante C, Ashley EA, Ioannidis JP. Randomized trial of personal genomics for preventive cardiology: design and challenges. Circulation. Cardiovascular Genetics. 5: 368-76. PMID 22715281 DOI: 10.1161/Circgenetics.112.962746 |
0.397 |
|
2012 |
deGoma EM, Knowles JW, Angeli F, Budoff MJ, Rader DJ. The evolution and refinement of traditional risk factors for cardiovascular disease. Cardiology in Review. 20: 118-29. PMID 22183062 DOI: 10.1097/Crd.0B013E318239B924 |
0.334 |
|
2011 |
Dewey FE, Chen R, Cordero SP, Ormond KE, Caleshu C, Karczewski KJ, Whirl-Carrillo M, Wheeler MT, Dudley JT, Byrnes JK, Cornejo OE, Knowles JW, Woon M, Sangkuhl K, Gong L, et al. Phased whole-genome genetic risk in a family quartet using a major allele reference sequence. Plos Genetics. 7: e1002280. PMID 21935354 DOI: 10.1371/Journal.Pgen.1002280 |
0.329 |
|
2011 |
Kraja AT, Vaidya D, Pankow JS, Goodarzi MO, Assimes TL, Kullo IJ, Sovio U, Mathias RA, Sun YV, Franceschini N, Absher D, Li G, Zhang Q, Feitosa MF, Glazer NL, ... ... Knowles JW, et al. A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium. Diabetes. 60: 1329-39. PMID 21386085 DOI: 10.2337/Db10-1011 |
0.346 |
|
2011 |
Schunkert H, König IR, Kathiresan S, Reilly MP, Assimes TL, Holm H, Preuss M, Stewart AF, Barbalic M, Gieger C, Absher D, Aherrahrou Z, Allayee H, Altshuler D, Anand SS, ... ... Knowles JW, et al. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nature Genetics. 43: 333-8. PMID 21378990 DOI: 10.1038/Ng.784 |
0.365 |
|
2011 |
Pan S, Dewey FE, Perez MV, Knowles JW, Chen R, Butte AJ, Ashley EA. Personalized Medicine and Cardiovascular Disease: From Genome to Bedside Current Cardiovascular Risk Reports. 5: 542-551. DOI: 10.1007/S12170-011-0202-4 |
0.346 |
|
2010 |
Assimes TL, Hólm H, Kathiresan S, Reilly MP, Thorleifsson G, Voight BF, Erdmann J, Willenborg C, Vaidya D, Xie C, Patterson CC, Morgan TM, Burnett MS, Li M, Hlatky MA, ... Knowles JW, et al. Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. Journal of the American College of Cardiology. 56: 1552-63. PMID 20933357 DOI: 10.1016/J.Jacc.2010.06.022 |
0.726 |
|
2010 |
Lango Allen H, Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F, Willer CJ, Jackson AU, Vedantam S, Raychaudhuri S, Ferreira T, Wood AR, Weyant RJ, Segrè AV, Speliotes EK, ... ... Knowles JW, et al. Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature. 467: 832-8. PMID 20881960 DOI: 10.1038/Nature09410 |
0.336 |
|
2008 |
Wheeler MT, Ho M, Knowles JW, Pavlovic A, Ashley EA. Pharmacogenetics of heart failure: evidence, opportunities, and challenges for cardiovascular pharmacogenomics. Journal of Cardiovascular Translational Research. 1: 25-36. PMID 20559955 DOI: 10.1007/S12265-007-9007-8 |
0.306 |
|
2008 |
Assimes TL, Knowles JW, Basu A, Iribarren C, Southwick A, Tang H, Absher D, Li J, Fair JM, Rubin GD, Sidney S, Fortmann SP, Go AS, Hlatky MA, Myers RM, et al. Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study. Human Molecular Genetics. 17: 2320-8. PMID 18443000 DOI: 10.1093/Hmg/Ddn132 |
0.351 |
|
2008 |
Knowles JW, Assimes TL, Boerwinkle E, Fortmann SP, Go A, Grove ML, Hlatky M, Iribarren C, Li J, Myers R, Risch N, Sidney S, Southwick A, Volcik KA, Quertermous T. Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD. Bmc Medical Genetics. 9: 23. PMID 18384690 DOI: 10.1186/1471-2350-9-23 |
0.319 |
|
2008 |
Assimes TL, Knowles JW, Priest JR, Basu A, Volcik KA, Southwick A, Tabor HK, Hartiala J, Allayee H, Grove ML, Tabibiazar R, Sidney S, Fortmann SP, Go A, Hlatky M, et al. Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease. Human Genetics. 123: 399-408. PMID 18369664 DOI: 10.1007/S00439-008-0489-5 |
0.358 |
|
2008 |
Assimes TL, Knowles JW, Priest JR, Basu A, Borchert A, Volcik KA, Grove ML, Tabor HK, Southwick A, Tabibiazar R, Sidney S, Boerwinkle E, Go AS, Iribarren C, Hlatky MA, et al. A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease. Atherosclerosis. 198: 136-44. PMID 17959182 DOI: 10.1016/J.Atherosclerosis.2007.09.003 |
0.364 |
|
2007 |
Knowles JW, Assimes TL, Li J, Quertermous T, Cooke JP. Genetic susceptibility to peripheral arterial disease: a dark corner in vascular biology. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 2068-78. PMID 17656669 DOI: 10.1161/01.Atv.0000282199.66398.8C |
0.346 |
|
2003 |
Alexander MR, Knowles JW, Nishikimi T, Maeda N. Increased atherosclerosis and smooth muscle cell hypertrophy in natriuretic peptide receptor A-/-apolipoprotein E-/- mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 1077-82. PMID 12702516 DOI: 10.1161/01.Atv.0000071702.45741.2E |
0.48 |
|
2003 |
Knowles JW, Erickson LM, Guy VK, Sigel CS, Wilder JC, Maeda N. Common variations in noncoding regions of the human natriuretic peptide receptor A gene have quantitative effects. Human Genetics. 112: 62-70. PMID 12483301 DOI: 10.1007/S00439-002-0834-Z |
0.508 |
|
2002 |
Ellmers LJ, Knowles JW, Kim HS, Smithies O, Maeda N, Cameron VA. Ventricular expression of natriuretic peptides in Npr1(-/-) mice with cardiac hypertrophy and fibrosis. American Journal of Physiology. Heart and Circulatory Physiology. 283: H707-14. PMID 12124219 DOI: 10.1152/Ajpheart.00677.2001 |
0.473 |
|
2002 |
Hodgin JB, Knowles JW, Kim HS, Smithies O, Maeda N. Interactions between endothelial nitric oxide synthase and sex hormones in vascular protection in mice. The Journal of Clinical Investigation. 109: 541-8. PMID 11854327 DOI: 10.1172/Jci14066 |
0.626 |
|
2001 |
Goy MF, Oliver PM, Purdy KE, Knowles JW, Fox JE, Mohler PJ, Qian X, Smithies O, Maeda N. Evidence for a novel natriuretic peptide receptor that prefers brain natriuretic peptide over atrial natriuretic peptide. The Biochemical Journal. 358: 379-87. PMID 11513736 DOI: 10.1042/0264-6021:3580379 |
0.604 |
|
2001 |
Knowles JW, Esposito G, Mao L, Hagaman JR, Fox JE, Smithies O, Rockman HA, Maeda N. Pressure-independent enhancement of cardiac hypertrophy in natriuretic peptide receptor A-deficient mice. The Journal of Clinical Investigation. 107: 975-84. PMID 11306601 DOI: 10.1172/Jci11273 |
0.478 |
|
2001 |
Knowles JW, Maeda N. Authors[rsquo ] reply: American Journal of Kidney Diseases. 37: 1322-1323. DOI: 10.1053/Ajkd.2001.23668 |
0.386 |
|
2000 |
Knowles JW, Maeda N. Genetic modifiers of atherosclerosis in mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 2336-45. PMID 11073835 DOI: 10.1161/01.Atv.20.11.2336 |
0.514 |
|
2000 |
Knowles JW, Reddick RL, Jennette JC, Shesely EG, Smithies O, Maeda N. Enhanced atherosclerosis and kidney dysfunction in eNOS(-/-)Apoe(-/-) mice are ameliorated by enalapril treatment. The Journal of Clinical Investigation. 105: 451-8. PMID 10683374 DOI: 10.1172/Jci8376 |
0.475 |
|
2000 |
Knowles J, Hodgin J, Maeda N. Genetic interaction between hypertension and atherosclerosis in mice Atherosclerosis. 151: 10. DOI: 10.1016/S0021-9150(00)80041-6 |
0.405 |
|
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