Ralph S. Baric - Publications

Affiliations: 
University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Microbiology Biology

464 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Liu X, Ng WH, Zusinaite E, Freitas J, Taylor A, Yerragunta V, Aavula SM, Gorriparthi S, Ponsekaran S, Bonda RL, Mani P, Nimmagadda SV, Wang S, Lello LS, Zaid A, ... ... Baric RS, et al. A single-dose intranasal live-attenuated codon deoptimized vaccine provides broad protection against SARS-CoV-2 and its variants. Nature Communications. 15: 7225. PMID 39187479 DOI: 10.1038/s41467-024-51535-y  0.354
2024 Voss WN, Mallory MA, Byrne PO, Marchioni JM, Knudson SA, Powers JM, Leist SR, Dadonaite B, Townsend DR, Kain J, Huang Y, Satterwhite E, Castillo IN, Mattocks M, Paresi C, ... ... Baric RS, et al. Hybrid immunity to SARS-CoV-2 arises from serological recall of IgG antibodies distinctly imprinted by infection or vaccination. Cell Reports. Medicine. 101668. PMID 39094579 DOI: 10.1016/j.xcrm.2024.101668  0.324
2024 Rhodin MHJ, Reyes AC, Balakrishnan A, Bisht N, Kelly NM, Gibbons JS, Lloyd J, Vaine M, Cressey T, Crepeau M, Shen R, Manalo N, Castillo J, Levene RE, Leonard D, ... ... Baric RS, et al. The small molecule inhibitor of SARS-CoV-2 3CLpro EDP-235 prevents viral replication and transmission in vivo. Nature Communications. 15: 6503. PMID 39090095 DOI: 10.1038/s41467-024-50931-8  0.353
2024 Pierre CN, Adams LE, Higgins JS, Anasti K, Goodman D, Mielke D, Stanfield-Oakley S, Powers JM, Li D, Rountree W, Wang Y, Edwards RJ, Alam SM, Ferrari G, Tomaras GD, ... ... Baric RS, et al. Non-neutralizing SARS-CoV-2 N-terminal domain antibodies protect mice against severe disease using Fc-mediated effector functions. Plos Pathogens. 20: e1011569. PMID 38900807 DOI: 10.1371/journal.ppat.1011569  0.32
2024 Martinez DR, Moreira FR, Catanzaro NJ, Diefenbacher MV, Zweigart MR, Gully KL, De la Cruz G, Brown AJ, Adams LE, Yount B, Baric TJ, Mallory ML, Conrad H, May SR, Dong S, ... ... Baric RS, et al. The oral nucleoside prodrug GS-5245 is efficacious against SARS-CoV-2 and other endemic, epidemic, and enzootic coronaviruses. Science Translational Medicine. 16: eadj4504. PMID 38776389 DOI: 10.1126/scitranslmed.adj4504  0.683
2024 Dillard JA, Taft-Benz SA, Knight AC, Anderson EJ, Pressey KD, Parotti B, Martinez SA, Diaz JL, Sarkar S, Madden EA, De la Cruz G, Adams LE, Dinnon KH, Leist SR, Martinez DR, ... ... Baric RS, et al. Adjuvant-dependent impact of inactivated SARS-CoV-2 vaccines during heterologous infection by a SARS-related coronavirus. Nature Communications. 15: 3738. PMID 38702297 DOI: 10.1038/s41467-024-47450-x  0.305
2024 Meganck RM, Edwards CE, Mallory ML, Lee RE, Dang H, Bailey AB, Wykoff JA, Gallant SC, Zhu DR, Yount BL, Kato T, Shaffer KM, Nakano S, Cawley AM, Sontake V, ... ... Baric RS, et al. SARS-CoV-2 variant of concern fitness and adaptation in primary human airway epithelia. Cell Reports. 43: 114076. PMID 38607917 DOI: 10.1016/j.celrep.2024.114076  0.36
2024 Boon ACM, Bricker TL, Fritch EJ, Leist SR, Gully K, Baric RS, Graham RL, Troan BV, Mahoney M, Janetka JW. Efficacy of host cell serine protease inhibitor MM3122 against SARS-CoV-2 for treatment and prevention of COVID-19. Journal of Virology. e0190323. PMID 38593045 DOI: 10.1128/jvi.01903-23  0.331
2024 Eisfeld AJ, Anderson LN, Fan S, Walters KB, Halfmann PJ, Westhoff Smith D, Thackray LB, Tan Q, Sims AC, Menachery VD, Schäfer A, Sheahan TP, Cockrell AS, Stratton KG, Webb-Robertson BM, ... ... Baric RS, et al. A compendium of multi-omics data illuminating host responses to lethal human virus infections. Scientific Data. 11: 328. PMID 38565538 DOI: 10.1038/s41597-024-03124-3  0.648
2024 Voss WN, Mallory MA, Byrne PO, Marchioni JM, Knudson SA, Powers JM, Leist SR, Dadonaite B, Townsend DR, Kain J, Huang Y, Satterwhite E, Castillo IN, Mattocks M, Paresi C, ... ... Baric RS, et al. Hybrid immunity to SARS-CoV-2 arises from serological recall of IgG antibodies distinctly imprinted by infection or vaccination. Biorxiv : the Preprint Server For Biology. PMID 38545622 DOI: 10.1101/2024.01.22.576742  0.31
2024 Schäfer A, Gralinski LE, Leist SR, Hampton BK, Mooney MA, Jensen KL, Graham RL, Agnihothram S, Jeng S, Chamberlin S, Bell TA, Scobey DT, Linnertz CL, VanBlargan LA, Thackray LB, ... ... Baric RS, et al. Genetic Loci Regulate Sarbecovirus Pathogenesis: A Comparison across Mice and Humans. Virus Research. 199357. PMID 38508400 DOI: 10.1016/j.virusres.2024.199357  0.347
2024 Boon ACM, L Bricker T, Fritch EJ, Leist SR, Gully K, Baric RS, Graham RL, Troan BV, Mahoney M, Janetka JW. Efficacy of Host Cell Serine Protease Inhibitor MM3122 against SARS-CoV-2 for Treatment and Prevention of COVID-19. Biorxiv : the Preprint Server For Biology. PMID 38405752 DOI: 10.1101/2024.02.09.579701  0.321
2024 Graham JB, Swarts JL, Leist SR, Schäfer A, Bell TA, Hock P, Farrington J, Shaw GD, Ferris MT, Pardo-Manuel de Villena F, Baric RS, Lund JM. Unique immune profiles in collaborative cross mice linked to survival and viral clearance upon infection. Iscience. 27: 109103. PMID 38361611 DOI: 10.1016/j.isci.2024.109103  0.341
2024 Cruz Cisneros MC, Anderson EJ, Hampton BK, Parotti B, Sarkar S, Taft-Benz S, Bell TA, Blanchard M, Dillard JA, Dinnon KH, Hock P, Leist SR, Madden EA, Shaw GD, West A, ... Baric RS, et al. Host Genetic Variation Impacts SARS-CoV-2 Vaccination Response in the Diversity Outbred Mouse Population. Vaccines. 12. PMID 38276675 DOI: 10.3390/vaccines12010103  0.309
2024 Powers JM, Leist SR, Mallory ML, Yount BL, Gully KL, Zweigart MR, Bailey AB, Sheahan TP, Harkema JR, Baric RS. Divergent pathogenetic outcomes in BALB/c mice following Omicron subvariant infection. Virus Research. 341: 199319. PMID 38224840 DOI: 10.1016/j.virusres.2024.199319  0.653
2023 Malewana RD, Stalls V, May A, Lu X, Martinez DR, Schäfer A, Li D, Barr M, Sutherland LL, Lee E, Parks R, Beck WE, Newman A, Bock KW, Minai M, ... ... Baric RS, et al. Broadly neutralizing antibody induction by non-stabilized SARS-CoV-2 Spike mRNA vaccination in nonhuman primates. Biorxiv : the Preprint Server For Biology. PMID 38187726 DOI: 10.1101/2023.12.18.572191  0.371
2023 Kapingidza AB, Marston DJ, Harris C, Wrapp D, Winters K, Mielke D, Xiaozhi L, Yin Q, Foulger A, Parks R, Barr M, Newman A, Schäfer A, Eaton A, Flores JM, ... ... Baric R, et al. Engineered immunogens to elicit antibodies against conserved coronavirus epitopes. Nature Communications. 14: 7897. PMID 38036525 DOI: 10.1038/s41467-023-43638-9  0.326
2023 Diefenbacher MV, Baric TJ, Martinez DR, Baric RS, Catanzaro NJ, Sheahan TP. A nano-luciferase expressing human coronavirus OC43 for countermeasure development. Virus Research. 199286. PMID 38016504 DOI: 10.1016/j.virusres.2023.199286  0.66
2023 Munt JE, Henein S, Adams C, Young E, Hou YJ, Conrad H, Zhu D, Dong S, Kose N, Yount B, Meganck RM, Tse LPV, Kuan G, Balmaseda A, Ricciardi MJ, ... ... Baric RS, et al. Homotypic antibodies target novel E glycoprotein domains after natural DENV 3 infection/vaccination. Cell Host & Microbe. PMID 37909048 DOI: 10.1016/j.chom.2023.10.004  0.307
2023 Martinez DR, Schäfer A, Gavitt TD, Mallory ML, Lee E, Catanzaro NJ, Chen H, Gully K, Scobey T, Korategere P, Brown A, Smith L, Parks R, Barr M, Newman A, ... ... Baric RS, et al. Vaccine-mediated protection against Merbecovirus and Sarbecovirus challenge in mice. Cell Reports. 113248. PMID 37858337 DOI: 10.1016/j.celrep.2023.113248  0.334
2023 Zhu DR, Rajesh AJ, Meganck RM, Young EF, Munt JE, Tse VL, Yount B, Conrad H, White L, Henein S, DeSilva AM, Baric RS. Dengue virus 4/2 envelope domain chimeric virus panel maps type-specific responses against dengue serotype 2. Mbio. e0081823. PMID 37800919 DOI: 10.1128/mbio.00818-23  0.378
2023 Tse LV, Hou YJ, McFadden E, Lee RE, Scobey TD, Leist SR, Martinez DR, Meganck RM, Schäfer A, Yount BL, Mascenik T, Powers JM, Randell SH, Zhang Y, Wang L, ... ... Baric RS, et al. A MERS-CoV antibody neutralizes a pre-emerging group 2c bat coronavirus. Science Translational Medicine. 15: eadg5567. PMID 37756379 DOI: 10.1126/scitranslmed.adg5567  0.403
2023 Hou YJ, Chiba S, Leist SR, Meganck RM, Martinez DR, Schäfer A, Catanzaro NJ, Sontake V, West A, Edwards CE, Yount B, Lee RE, Gallant SC, Zost SJ, Powers J, ... ... Baric RS, et al. Host range, transmissibility and antigenicity of a pangolin coronavirus. Nature Microbiology. 8: 1820-1833. PMID 37749254 DOI: 10.1038/s41564-023-01476-x  0.388
2023 Ojha D, Hill CS, Zhou S, Evans AB, Leung JM, Lewis CS, Amblard F, Schinazi RF, Baric RS, Peterson KE, Swanstrom R. -Hydroxycytidine/Molnupiravir Inhibits RNA-Virus Induced Encephalitis by Producing Mutated Viruses with Reduced Fitness. Biorxiv : the Preprint Server For Biology. PMID 37662274 DOI: 10.1101/2023.08.22.554316  0.341
2023 Sessions Z, Bobrowski T, Martin HJ, Beasley JT, Kothari A, Phares T, Li M, Alves VM, Scotti MT, Moorman NJ, Baric R, Tropsha A, Muratov EN. Praemonitus praemunitus: can we forecast and prepare for future viral disease outbreaks? Fems Microbiology Reviews. PMID 37596064 DOI: 10.1093/femsre/fuad048  0.323
2023 Pierre CN, Adams LE, Anasti K, Goodman D, Stanfield-Oakley S, Powers JM, Li D, Rountree W, Wang Y, Edwards RJ, Alam SM, Ferrari G, Tomaras GD, Haynes BF, Baric RS, et al. Non-neutralizing SARS-CoV-2 N-terminal domain antibodies protect mice against severe disease using Fc-mediated effector functions. Biorxiv : the Preprint Server For Biology. PMID 37546738 DOI: 10.1101/2023.07.25.550460  0.317
2023 Martinez DR, Moreira FR, Zweigart MR, Gully KL, la Cruz G, Brown AJ, Adams LE, Catanzaro N, Yount B, Baric TJ, Mallory ML, Conrad H, May SR, Dong S, Scobey DT, ... ... Baric RS, et al. Efficacy of the oral nucleoside prodrug GS-5245 (Obeldesivir) against SARS-CoV-2 and coronaviruses with pandemic potential. Biorxiv : the Preprint Server For Biology. PMID 37425890 DOI: 10.1101/2023.06.27.546784  0.689
2023 Martinez DR, Schaefer A, Gavitt TD, Mallory ML, Lee E, Catanzaro NJ, Chen H, Gully K, Scobey T, Korategere P, Brown A, Smith L, Parks R, Barr M, Newman A, ... ... Baric RS, et al. Vaccine-mediated protection against merbecovirus and sarbecovirus challenge in mice. Biorxiv : the Preprint Server For Biology. PMID 37293083 DOI: 10.1101/2023.05.22.540829  0.31
2023 Feng Y, Yuan M, Powers JM, Hu M, Munt JE, Arunachalam PS, Leist SR, Bellusci L, Kim J, Sprouse KR, Adams LE, Sundaramurthy S, Zhu X, Shirreff LM, Mallory ML, ... ... Baric RS, et al. Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine. Science Translational Medicine. 15: eadg7404. PMID 37163615 DOI: 10.1126/scitranslmed.adg7404  0.313
2023 Mackin SR, Desai P, Whitener BM, Karl CE, Liu M, Baric RS, Edwards DK, Chicz TM, McNamara RP, Alter G, Diamond MS. Fc-γR-dependent antibody effector functions are required for vaccine-mediated protection against antigen-shifted variants of SARS-CoV-2. Nature Microbiology. 8: 569-580. PMID 37012355 DOI: 10.1038/s41564-023-01359-1  0.383
2023 Adams LE, Leist SR, Dinnon KH, West A, Gully KL, Anderson EJ, Loome JF, Madden EA, Powers JM, Schäfer A, Sarkar S, Castillo IN, Maron JS, McNamara RP, Bertera HL, ... ... Baric RS, et al. Fc-mediated pan-sarbecovirus protection after alphavirus vector vaccination. Cell Reports. 42: 112326. PMID 37000623 DOI: 10.1016/j.celrep.2023.112326  0.359
2023 Young E, Yount B, Pantoja P, Henein S, Meganck RM, McBride J, Munt JE, Baric TJ, Zhu D, Scobey T, Dong S, Tse LV, Martinez MI, Burgos AG, Graham RL, ... ... Baric RS, et al. A live dengue virus vaccine carrying a chimeric envelope glycoprotein elicits dual DENV2-DENV4 serotype-specific immunity. Nature Communications. 14: 1371. PMID 36914616 DOI: 10.1038/s41467-023-36702-x  0.366
2023 Zhou P, Song G, Liu H, Yuan M, He WT, Beutler N, Zhu X, Tse LV, Martinez DR, Schäfer A, Anzanello F, Yong P, Peng L, Dueker K, Musharrafieh R, ... ... Baric RS, et al. Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease. Immunity. PMID 36889306 DOI: 10.1016/j.immuni.2023.02.005  0.318
2023 Lindesmith LC, Brewer-Jensen PD, Conrad H, O'Reilly KM, Mallory ML, Kelly D, Williams R, Edmunds WJ, Allen DJ, Breuer J, Baric RS. Emergent variant modeling of the serological repertoire to norovirus in young children. Cell Reports. Medicine. 100954. PMID 36854303 DOI: 10.1016/j.xcrm.2023.100954  0.369
2023 Hao L, Hsiang TY, Dalmat RR, Ireton R, Morton JF, Stokes C, Netland J, Hale M, Thouvenel C, Wald A, Franko NM, Huden K, Chu HY, Sigal A, Greninger AL, ... ... Baric RS, et al. Dynamics of SARS-CoV-2 VOC Neutralization and Novel mAb Reveal Protection against Omicron. Viruses. 15. PMID 36851745 DOI: 10.3390/v15020530  0.39
2022 Davis MA, Voss K, Turnbull JB, Gustin AT, Knoll M, Muruato A, Hsiang TY, Dinnon Iii KH, Leist SR, Nickel K, Baric RS, Ladiges W, Akilesh S, Smith KD, Gale M. A C57BL/6 Mouse Model of SARS-CoV-2 Infection Recapitulates Age- and Sex-Based Differences in Human COVID-19 Disease and Recovery. Vaccines. 11. PMID 36679892 DOI: 10.3390/vaccines11010047  0.382
2022 de Carvalho RVH, Ersching J, Barbulescu A, Hobbs A, Castro TBR, Mesin L, Jacobsen JT, Phillips BK, Hoffmann HH, Parsa R, Canesso MCC, Nowosad CR, Feng A, Leist SR, Baric RS, et al. Clonal replacement sustains long-lived germinal centers primed by respiratory viruses. Cell. PMID 36565697 DOI: 10.1016/j.cell.2022.11.031  0.335
2022 Mackin SR, Desai P, Whitener BM, Karl CE, Liu M, Baric RS, Edwards DK, Chicz TM, McNamara RP, Alter G, Diamond MS. Fcγ receptor-dependent antibody effector functions are required for vaccine protection against infection by antigenic variants of SARS-CoV-2. Biorxiv : the Preprint Server For Biology. PMID 36482975 DOI: 10.1101/2022.11.27.518117  0.372
2022 Adams LE, Leist SR, Dinnon KH, West A, Gully KL, Anderson EJ, Loome JF, Madden EA, Powers JM, Schäfer A, Sarkar S, Castillo IN, Maron JS, McNamara RP, Bertera HL, ... ... Baric RS, et al. Fc mediated pan-sarbecovirus protection after alphavirus vector vaccination. Biorxiv : the Preprint Server For Biology. PMID 36482964 DOI: 10.1101/2022.11.28.518175  0.344
2022 Milligan EC, Olstad K, Williams CA, Mallory M, Cano P, Cross KA, Munt JE, Garrido C, Lindesmith L, Watanabe J, Usachenko JL, Hopkins L, Immareddy R, Lakshmanappa YS, Elizaldi SR, ... ... Baric R, et al. Infant rhesus macaques immunized against SARS-CoV-2 are protected against heterologous virus challenge one year later. Science Translational Medicine. eadd6383. PMID 36454813 DOI: 10.1126/scitranslmed.add6383  0.301
2022 Davis M, Voss K, Turnbull JB, Gustin AT, Knoll M, Muruato A, Hsiang TY, Dinnon IKH, Leist SR, Nickel K, Baric RS, Ladiges W, Akilesh S, Smith KD, Gale M. A C57BL/6 Mouse model of SARS-CoV-2 infection recapitulates age- and sex-based differences in human COVID-19 disease and recovery. Research Square. PMID 36415465 DOI: 10.21203/rs.3.rs-2194450/v1  0.373
2022 Li D, Martinez DR, Schäfer A, Chen H, Barr M, Sutherland LL, Lee E, Parks R, Mielke D, Edwards W, Newman A, Bock KW, Minai M, Nagata BM, Gagne M, ... ... Baric RS, et al. Breadth of SARS-CoV-2 neutralization and protection induced by a nanoparticle vaccine. Nature Communications. 13: 6309. PMID 36274085 DOI: 10.1038/s41467-022-33985-4  0.33
2022 Lindesmith LC, Boshier FAT, Brewer-Jensen PD, Roy S, Costantini V, Mallory ML, Zweigart M, May SR, Conrad H, O'Reilly KM, Kelly D, Celma CC, Beard S, Williams R, Tutill HJ, ... ... Baric RS, et al. Immune Imprinting Drives Human Norovirus Potential for Global Spread. Mbio. e0186122. PMID 36102514 DOI: 10.1128/mbio.01861-22  0.334
2022 Hao L, Hsiang TY, Dalmat RR, Ireton R, Morton J, Stokes C, Netland J, Hale M, Thouvenel C, Wald A, Franko NM, Huden K, Chu H, Greninger A, Tilles S, ... ... Baric RS, et al. Dynamics of SARS-CoV-2 VOC neutralization and novel mAb reveal protection against Omicron. Medrxiv : the Preprint Server For Health Sciences. PMID 36032965 DOI: 10.1101/2022.08.12.22278720  0.334
2022 Biering SB, Sarnik SA, Wang E, Zengel JR, Leist SR, Schäfer A, Sathyan V, Hawkins P, Okuda K, Tau C, Jangid AR, Duffy CV, Wei J, Gilmore RC, Alfajaro MM, ... ... Baric RS, et al. Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection. Nature Genetics. PMID 35879412 DOI: 10.1038/s41588-022-01131-x  0.307
2022 Dinnon KH, Leist SR, Okuda K, Dang H, Fritch EJ, Gully KL, De la Cruz G, Evangelista MD, Asakura T, Gilmore RC, Hawkins P, Nakano S, West A, Schäfer A, Gralinski LE, ... ... Baric RS, et al. SARS-CoV-2 infection produces chronic pulmonary epithelial and immune cell dysfunction with fibrosis in mice. Science Translational Medicine. eabo5070. PMID 35857635 DOI: 10.1126/scitranslmed.abo5070  0.303
2022 Edwards CE, Tata A, Baric RS. Human lung organoids as a model for respiratory virus replication and countermeasure performance in human hosts. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 35850445 DOI: 10.1016/j.trsl.2022.07.002  0.301
2022 Gallichotte EN, Henein S, Nivarthi U, Delacruz M, Scobey T, Bonaparte M, Moser J, Munteanu A, Baric R, de Silva AM. Vaccine-induced antibodies to contemporary strains of dengue virus type 4 show a mechanistic correlate of protective immunity. Cell Reports. 39: 110930. PMID 35675766 DOI: 10.1016/j.celrep.2022.110930  0.338
2022 He WT, Musharrafieh R, Song G, Dueker K, Tse LV, Martinez DR, Schäfer A, Callaghan S, Yong P, Beutler N, Torres JL, Volk RM, Zhou P, Yuan M, Liu H, ... ... Baric RS, et al. Targeted isolation of diverse human protective broadly neutralizing antibodies against SARS-like viruses. Nature Immunology. 23: 960-970. PMID 35654851 DOI: 10.1038/s41590-022-01222-1  0.357
2022 Stevens LJ, Pruijssers AJ, Lee HW, Gordon CJ, Tchesnokov EP, Gribble J, George AS, Hughes TM, Lu X, Li J, Perry JK, Porter DP, Cihlar T, Sheahan TP, Baric RS, et al. Mutations in the SARS-CoV-2 RNA dependent RNA polymerase confer resistance to remdesivir by distinct mechanisms. Science Translational Medicine. eabo0718. PMID 35482820 DOI: 10.1126/scitranslmed.abo0718  0.615
2022 Tse LV, Meganck RM, Dong S, Adams LE, White LJ, Mallory ML, Jadi R, de Silva AM, Baric RS. Generation of Mature DENVs via Genetic Modification and Directed Evolution. Mbio. e0038622. PMID 35481749 DOI: 10.1128/mbio.00386-22  0.326
2022 DeGrace MM, Ghedin E, Frieman MB, Krammer F, Grifoni A, Alisoltani A, Alter G, Amara RR, Baric RS, Barouch DH, Bloom JD, Bloyet LM, Bonenfant G, Boon ACM, Boritz EA, et al. Defining the risk of SARS-CoV-2 variants on immune protection. Nature. PMID 35361968 DOI: 10.1038/s41586-022-04690-5  0.792
2022 Yen M, Ren J, Liu Q, Glassman CR, Sheahan TP, Picton LK, Moreira FR, Rustagi A, Jude KM, Zhao X, Blish CA, Baric RS, Su LL, Garcia KC. Facile discovery of surrogate cytokine agonists. Cell. PMID 35325595 DOI: 10.1016/j.cell.2022.02.025  0.55
2022 Schäfer A, Martinez DR, Won JJ, Meganck RM, Moreira FR, Brown AJ, Gully KL, Zweigart MR, Conrad WS, May SR, Dong S, Kalla R, Chun K, Du Pont V, Babusis D, ... ... Baric RS, et al. Therapeutic treatment with an oral prodrug of the remdesivir parental nucleoside is protective against SARS-CoV-2 pathogenesis in mice. Science Translational Medicine. eabm3410. PMID 35315683 DOI: 10.1126/scitranslmed.abm3410  0.686
2022 Zhou P, Song G, He WT, Beutler N, Tse LV, Martinez DR, Schäfer A, Anzanello F, Yong P, Peng L, Dueker K, Musharrafieh R, Callaghan S, Capozzola T, Yuan M, ... ... Baric RS, et al. Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause severe disease. Biorxiv : the Preprint Server For Biology. PMID 35291291 DOI: 10.1101/2022.03.04.479488  0.357
2022 Edwards AM, Baric RS, Saphire EO, Ulmer JB. Stopping pandemics before they start: Lessons learned from SARS-CoV-2. Science (New York, N.Y.). 375: 1133-1139. PMID 35271333 DOI: 10.1126/science.abn1900  0.324
2022 He WT, Musharrafieh R, Song G, Dueker K, Tse LV, Martinez DR, Schäfer A, Callaghan S, Yong P, Beutler N, Torres JL, Volk RM, Zhou P, Yuan M, Liu H, ... ... Baric RS, et al. Targeted isolation of panels of diverse human protective broadly neutralizing antibodies against SARS-like viruses. Biorxiv : the Preprint Server For Biology. PMID 35169804 DOI: 10.1101/2021.09.08.459480  0.36
2022 Li D, Martinez DR, Schäfer A, Chen H, Barr M, Sutherland LL, Lee E, Parks R, Mielke D, Edwards W, Newman A, Bock KW, Minai M, Nagata BM, Gagne M, ... ... Baric RS, et al. Breadth of SARS-CoV-2 Neutralization and Protection Induced by a Nanoparticle Vaccine. Biorxiv : the Preprint Server For Biology. PMID 35118474 DOI: 10.1101/2022.01.26.477915  0.347
2022 Chiba S, Kiso M, Nakajima N, Iida S, Maemura T, Kuroda M, Sato Y, Ito M, Okuda M, Yamada S, Iwatsuki-Horimoto K, Watanabe T, Imai M, Armbrust T, Baric RS, et al. Co-administration of Favipiravir and the Remdesivir Metabolite GS-441524 Effectively Reduces SARS-CoV-2 Replication in the Lungs of the Syrian Hamster Model. Mbio. e0304421. PMID 35100870 DOI: 10.1128/mbio.03044-21  0.319
2022 Narowski TM, Raphel K, Adams LE, Huang J, Vielot NA, Jadi R, de Silva AM, Baric RS, Lafleur JE, Premkumar L. SARS-CoV-2 mRNA vaccine induces robust specific and cross-reactive IgG and unequal neutralizing antibodies in naive and previously infected people. Cell Reports. 110336. PMID 35090596 DOI: 10.1016/j.celrep.2022.110336  0.311
2022 Becker J, Stanifer ML, Leist SR, Stolp B, Maiakovska O, West A, Wiedtke E, Börner K, Ghanem A, Ambiel I, Tse LV, Fackler OT, Baric RS, Boulant S, Grimm D. Ex vivo and in vivo suppression of SARS-CoV-2 with combinatorial AAV-RNAi expression vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 35038579 DOI: 10.1016/j.ymthe.2022.01.024  0.382
2022 Fischer WA, Eron JJ, Holman W, Cohen MS, Fang L, Szewczyk LJ, Sheahan TP, Baric R, Mollan KR, Wolfe CR, Duke ER, Azizad MM, Borroto-Esoda K, Wohl DA, Coombs RW, et al. A phase 2a clinical trial of molnupiravir in patients with COVID-19 shows accelerated SARS-CoV-2 RNA clearance and elimination of infectious virus. Science Translational Medicine. 14: eabl7430. PMID 34941423 DOI: 10.1126/scitranslmed.abl7430  0.602
2021 Mollan KR, Eron JJ, Krajewski TJ, Painter W, Duke ER, Morse CG, Goecker EA, Premkumar L, Wolfe CR, Szewczyk LJ, Alabanza PL, Loftis AJ, Degli-Angeli EJ, Brown AJ, Dragavon JA, ... ... Baric RS, et al. Infectious Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Virus in Symptomatic Coronavirus Disease 2019 (COVID-19) Outpatients: Host, Disease, and Viral Correlates. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 35022711 DOI: 10.1093/cid/ciab968  0.66
2021 Hsieh CL, Werner AP, Leist SR, Stevens LJ, Falconer E, Goldsmith JA, Chou CW, Abiona OM, West A, Westendorf K, Muthuraman K, Fritch EJ, Dinnon KH, Schäfer A, Denison MR, ... ... Baric RS, et al. Stabilized coronavirus spike stem elicits a broadly protective antibody. Cell Reports. 109929. PMID 34710354 DOI: 10.1016/j.celrep.2021.109929  0.314
2021 Zweigart MR, Becker-Dreps S, Bucardo F, González F, Baric RS, Lindesmith LC. Serological Humoral Immunity Following Natural Infection of Children with High Burden Gastrointestinal Viruses. Viruses. 13. PMID 34696463 DOI: 10.3390/v13102033  0.303
2021 Walls AC, Miranda MC, Schäfer A, Pham MN, Greaney A, Arunachalam PS, Navarro MJ, Tortorici MA, Rogers K, O'Connor MA, Shirreff L, Ferrell DE, Bowen J, Brunette N, Kepl E, ... ... Baric RS, et al. Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines. Cell. PMID 34619077 DOI: 10.1016/j.cell.2021.09.015  0.632
2021 Yamin R, Jones AT, Hoffmann HH, Schäfer A, Kao KS, Francis RL, Sheahan TP, Baric RS, Rice CM, Ravetch JV, Bournazos S. Fc-engineered antibody therapeutics with improved anti-SARS-CoV-2 efficacy. Nature. PMID 34547765 DOI: 10.1038/s41586-021-04017-w  0.625
2021 Schäfer A, Martinez DR, Won JJ, Moreira FR, Brown AJ, Gully KL, Kalla R, Chun K, Du Pont V, Babusis D, Tang J, Murakami E, Subramanian R, Barrett KT, Bleier BJ, ... ... Baric RS, et al. Therapeutic efficacy of an oral nucleoside analog of remdesivir against SARS-CoV-2 pathogenesis in mice. Biorxiv : the Preprint Server For Biology. PMID 34545367 DOI: 10.1101/2021.09.13.460111  0.671
2021 Tostanoski LH, Gralinski LE, Martinez DR, Schaefer A, Mahrokhian SH, Li Z, Nampanya F, Wan H, Yu J, Chang A, Liu J, McMahan K, Ventura JD, Dinnon KH, Leist SR, ... Baric RS, et al. Protective efficacy of rhesus adenovirus COVID-19 vaccines against mouse-adapted SARS-CoV-2. Journal of Virology. JVI0097421. PMID 34523968 DOI: 10.1128/JVI.00974-21  0.342
2021 Geng Q, Tai W, Baxter VK, Shi J, Wan Y, Zhang X, Montgomery SA, Taft-Benz SA, Anderson EJ, Knight AC, Dinnon KH, Leist SR, Baric RS, Shang J, Hong SW, et al. Novel virus-like nanoparticle vaccine effectively protects animal model from SARS-CoV-2 infection. Plos Pathogens. 17: e1009897. PMID 34492082 DOI: 10.1371/journal.ppat.1009897  0.327
2021 Zhang K, Zheludev IN, Hagey RJ, Haslecker R, Hou YJ, Kretsch R, Pintilie GD, Rangan R, Kladwang W, Li S, Wu MT, Pham EA, Bernardin-Souibgui C, Baric RS, Sheahan TP, et al. Cryo-EM and antisense targeting of the 28-kDa frameshift stimulation element from the SARS-CoV-2 RNA genome. Nature Structural & Molecular Biology. PMID 34426697 DOI: 10.1038/s41594-021-00653-y  0.595
2021 Sims AC, Mitchell HD, Gralinski LE, Kyle JE, Burnum-Johnson KE, Lam M, Fulcher ML, West A, Smith RD, Randell SH, Metz TO, Sheahan TP, Waters KM, Baric RS. Unfolded Protein Response Inhibition Reduces Middle East Respiratory Syndrome Coronavirus-Induced Acute Lung Injury. Mbio. e0157221. PMID 34372702 DOI: 10.1128/mBio.01572-21  0.656
2021 Martinez DR, Schäfer A, Leist SR, Li D, Gully K, Yount B, Feng JY, Bunyan E, Porter DP, Cihlar T, Montgomery SA, Haynes BF, Baric RS, Nussenzweig MC, Sheahan TP. Prevention and therapy of SARS-CoV-2 and the B.1.351 variant in mice. Cell Reports. 109450. PMID 34289384 DOI: 10.1016/j.celrep.2021.109450  0.617
2021 DiPiazza AT, Leist SR, Abiona OM, Moliva JI, Werner A, Minai M, Nagata BM, Bock KW, Phung E, Schäfer A, Dinnon KH, Chang LA, Loomis RJ, Boyoglu-Barnum S, Alvarado GS, ... ... Baric RS, et al. COVID-19 vaccine mRNA-1273 elicits a protective immune profile in mice that is not associated with vaccine-enhanced disease upon SARS-CoV-2 challenge. Immunity. PMID 34270939 DOI: 10.1016/j.immuni.2021.06.018  0.354
2021 Li D, Edwards RJ, Manne K, Martinez DR, Schäfer A, Alam SM, Wiehe K, Lu X, Parks R, Sutherland LL, Oguin TH, McDanal C, Perez LG, Mansouri K, Gobeil SMC, ... ... Baric RS, et al. In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. Cell. PMID 34242577 DOI: 10.1016/j.cell.2021.06.021  0.315
2021 Martinez DR, Schäfer A, Leist SR, De la Cruz G, West A, Atochina-Vasserman EN, Lindesmith LC, Pardi N, Parks R, Barr M, Li D, Yount B, Saunders KO, Weissman D, Haynes BF, ... ... Baric RS, et al. Chimeric spike mRNA vaccines protect against Sarbecoviru challenge in mice. Science (New York, N.Y.). PMID 34214046 DOI: 10.1126/science.abi4506  0.307
2021 Fischer W, Eron JJ, Holman W, Cohen MS, Fang L, Szewczyk LJ, Sheahan TP, Baric R, Mollan KR, Wolfe CR, Duke ER, Azizad MM, Borroto-Esoda K, Wohl DA, Loftis AJ, et al. Molnupiravir, an Oral Antiviral Treatment for COVID-19. Medrxiv : the Preprint Server For Health Sciences. PMID 34159342 DOI: 10.1101/2021.06.17.21258639  0.589
2021 Tostanoski LH, Gralinski LE, Martinez DR, Schaefer A, Mahrokhian SH, Li Z, Nampanya F, Wan H, Yu J, Chang A, Liu J, McMahan K, Dinnon KH, Leist SR, Baric RS, et al. Protective efficacy of rhesus adenovirus COVID-19 vaccines against mouse-adapted SARS-CoV-2. Biorxiv : the Preprint Server For Biology. PMID 34159335 DOI: 10.1101/2021.06.14.448461  0.361
2021 Mollan KR, Eron JJ, Krajewski TJ, Painter W, Duke ER, Morse CG, Goecker EA, Premkumar L, Wolfe CR, Szewczyk LJ, Alabanza PL, Loftis AJ, Degli-Angeli EJ, Brown AJ, Dragavon JA, ... ... Baric RS, et al. SARS-CoV-2 infectious virus, viral RNA in nasopharyngeal swabs, and serostatus of symptomatic COVID-19 outpatients in the United States. Medrxiv : the Preprint Server For Health Sciences. PMID 34100024 DOI: 10.1101/2021.05.28.21258011  0.648
2021 Ravetch J, Yamin R, Jones A, Hoffmann HH, Kao K, Francis R, Sheahan T, Baric R, Rice C, Bournazos S. Fc-engineered antibody therapeutics with improved efficacy against COVID-19. Research Square. PMID 34075373 DOI: 10.21203/rs.3.rs-555612/v1  0.628
2021 Shiakolas AR, Kramer KJ, Wrapp D, Richardson SI, Schäfer A, Wall S, Wang N, Janowska K, Pilewski KA, Venkat R, Parks R, Manamela NP, Raju N, Fechter EF, Holt CM, ... ... Baric RS, et al. Cross-reactive coronavirus antibodies with diverse epitope specificities and Fc effector functions. Cell Reports. Medicine. 100313. PMID 34056628 DOI: 10.1016/j.xcrm.2021.100313  0.309
2021 Feng S, Heath E, Jefferson B, Joslyn C, Kvinge H, Mitchell HD, Praggastis B, Eisfeld AJ, Sims AC, Thackray LB, Fan S, Walters KB, Halfmann PJ, Westhoff-Smith D, Tan Q, ... ... Baric RS, et al. Hypergraph models of biological networks to identify genes critical to pathogenic viral response. Bmc Bioinformatics. 22: 287. PMID 34051754 DOI: 10.1186/s12859-021-04197-2  0.554
2021 van Loben Sels JM, Meredith LW, Sosnovtsev SV, de Graaf M, Koopmans MPG, Lindesmith LC, Baric RS, Green KY, Goodfellow IG. A luciferase-based approach for measuring HBGA blockade antibody titers against human norovirus. Journal of Virological Methods. 114196. PMID 34019938 DOI: 10.1016/j.jviromet.2021.114196  0.305
2021 Schäfer A, Gralinski LE, Leist SR, Winkler ES, Hampton BK, Mooney MA, Jensen KL, Graham RL, Agnihothram S, Jeng S, Chamberlin S, Bell TA, Scobey DT, VanBlargan LA, Thackray LB, ... ... Baric RS, et al. Common Mechanism of SARS-CoV and SARS-CoV-2 Pathogenesis across Species. Biorxiv : the Preprint Server For Biology. PMID 34013261 DOI: 10.1101/2021.05.14.444205  0.305
2021 Saunders KO, Lee E, Parks R, Martinez DR, Li D, Chen H, Edwards RJ, Gobeil S, Barr M, Mansouri K, Alam SM, Sutherland LL, Cai F, Sanzone AM, Berry M, ... ... Baric RS, et al. Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses. Nature. PMID 33971664 DOI: 10.1038/s41586-021-03594-0  0.333
2021 Zhou S, Hill CS, Sarkar S, Tse LV, Woodburn BMD, Schinazi RF, Sheahan TP, Baric RS, Heise MT, Swanstrom R. β-D-N 4-hydroxycytidine (NHC) Inhibits SARS-CoV-2 Through Lethal Mutagenesis But Is Also Mutagenic To Mammalian Cells. The Journal of Infectious Diseases. PMID 33961695 DOI: 10.1093/infdis/jiab247  0.596
2021 Martinez DR, Schaefer A, Gobeil S, Li D, De la Cruz G, Parks R, Lu X, Barr M, Manne K, Mansouri K, Edwards RJ, Yount B, Anasti K, Montgomery SA, Shen S, ... ... Baric RS, et al. A broadly neutralizing antibody protects against SARS-CoV, pre-emergent bat CoVs, and SARS-CoV-2 variants in mice. Biorxiv : the Preprint Server For Biology. PMID 33948590 DOI: 10.1101/2021.04.27.441655  0.33
2021 Jones BE, Brown-Augsburger PL, Corbett KS, Westendorf K, Davies J, Cujec TP, Wiethoff CM, Blackbourne JL, Heinz BA, Foster D, Higgs RE, Balasubramaniam D, Wang L, Zhang Y, Yang ES, ... ... Baric RS, et al. The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in non-human primates. Science Translational Medicine. PMID 33820835 DOI: 10.1126/scitranslmed.abf1906  0.365
2021 Zhou S, Hill CS, Clark MU, Sheahan TP, Baric R, Swanstrom R. Primer ID Next-Generation Sequencing for the Analysis of a Broad Spectrum Antiviral Induced Transition Mutations and Errors Rates in a Coronavirus Genome. Bio-Protocol. 11: e3938. PMID 33796612 DOI: 10.21769/BioProtoc.3938  0.585
2021 Puhl AC, Fritch EJ, Lane TR, Tse LV, Yount BL, Sacramento CQ, Fintelman-Rodrigues N, Tavella TA, Maranhão Costa FT, Weston S, Logue J, Frieman M, Premkumar L, Pearce KH, Hurst BL, ... ... Baric RS, et al. Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine, and Pyronaridine: Activity against SARS-CoV-2 and Potential Mechanisms. Acs Omega. 6: 7454-7468. PMID 33778258 DOI: 10.1021/acsomega.0c05996  0.787
2021 Walls AC, Miranda MC, Pham MN, Schäfer A, Greaney A, Arunachalam PS, Navarro MJ, Tortorici MA, Rogers K, O'Connor MA, Shireff L, Ferrell DE, Brunette N, Kepl E, Bowen J, ... ... Baric R, et al. Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines. Biorxiv : the Preprint Server For Biology. PMID 33758839 DOI: 10.1101/2021.03.15.435528  0.643
2021 Martinez DR, Schaefer A, Leist SR, De la Cruz G, West A, Atochina-Vasserman EN, Parks R, Barr M, Li D, Yount B, Saunders KO, Weissman D, Haynes BF, Montgomery SA, Baric RS. Chimeric spike mRNA vaccines protect against sarbecovirus challenge in mice. Biorxiv : the Preprint Server For Biology. PMID 33758837 DOI: 10.1101/2021.03.11.434872  0.337
2021 Adams LE, Dinnon KH, Hou YJ, Sheahan TP, Heise MT, Baric RS. Critical ACE2 Determinants of SARS-CoV-2 and Group 2B Coronavirus Infection and Replication. Mbio. 12. PMID 33727353 DOI: 10.1128/mBio.03149-20  0.652
2021 Yu J, Li Z, He X, Gebre MS, Bondzie EA, Wan H, Jacob-Dolan C, Martinez DR, Nkolola JP, Baric RS, Barouch DH. Deletion of the SARS-CoV-2 Spike Cytoplasmic Tail Increases Infectivity in Pseudovirus Neutralization Assays. Journal of Virology. PMID 33727331 DOI: 10.1128/JVI.00044-21  0.392
2021 White LJ, Young EF, Stoops MJ, Henein SR, Adams EC, Baric RS, de Silva AM. Defining levels of dengue virus serotype-specific neutralizing antibodies induced by a live attenuated tetravalent dengue vaccine (TAK-003). Plos Neglected Tropical Diseases. 15: e0009258. PMID 33711074 DOI: 10.1371/journal.pntd.0009258  0.336
2021 Saunders KO, Lee E, Parks R, Martinez DR, Li D, Chen H, Edwards RJ, Gobeil S, Barr M, Mansouri K, Alam SM, Sutherland LL, Cai F, Sanzone AM, Berry M, ... ... Baric RS, et al. SARS-CoV-2 vaccination induces neutralizing antibodies against pandemic and pre-emergent SARS-related coronaviruses in monkeys. Biorxiv : the Preprint Server For Biology. PMID 33619494 DOI: 10.1101/2021.02.17.431492  0.354
2021 Wahl A, Gralinski LE, Johnson CE, Yao W, Kovarova M, Dinnon KH, Liu H, Madden VJ, Krzystek HM, De C, White KK, Gully K, Schäfer A, Zaman T, Leist SR, ... ... Baric RS, et al. SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801. Nature. PMID 33561864 DOI: 10.1038/s41586-021-03312-w  0.349
2021 Martinez DR, Schaefer A, Leist SR, Gully K, Feng JY, Bunyan E, Porter DP, Cihlar T, Montgomery SA, Baric RS, Nussenzweig MC, Sheahan TP. Early therapy with remdesivir and antibody combinations improves COVID-19 disease in mice. Biorxiv : the Preprint Server For Biology. PMID 33532765 DOI: 10.1101/2021.01.27.428478  0.608
2021 Dagotto G, Mercado NB, Martinez DR, Hou YJ, Nkolola JP, Carnahan RH, Crowe JE, Baric RS, Barouch DH. Comparison of Subgenomic and Total RNA in SARS-CoV-2 Challenged Rhesus Macaques. Journal of Virology. PMID 33472939 DOI: 10.1128/JVI.02370-20  0.354
2021 Dinnon KH, Leist SR, Schäfer A, Edwards CE, Martinez DR, Montgomery SA, West A, Yount BL, Hou YJ, Adams LE, Gully KL, Brown AJ, Huang E, Bryant MD, Choong IC, ... ... Baric RS, et al. Publisher Correction: A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures. Nature. PMID 33469219 DOI: 10.1038/s41586-020-03107-5  0.555
2021 Pattekar A, Mayer LS, Lau CW, Liu C, Palko O, Bewtra M, Consortium HPAP, Lindesmith LC, Brewer-Jensen PD, Baric RS, Betts MR, Naji A, Wherry EJ, Tomov VT. Norovirus-Specific CD8 T Cell Responses in Human Blood and Tissues. Cellular and Molecular Gastroenterology and Hepatology. PMID 33444817 DOI: 10.1016/j.jcmgh.2020.12.012  0.337
2021 Martinez DR, Metz SW, Baric RS. Dengue Vaccines: The Promise and Pitfalls of Antibody-Mediated Protection. Cell Host & Microbe. 29: 13-22. PMID 33444553 DOI: 10.1016/j.chom.2020.12.011  0.316
2021 Li D, Edwards RJ, Manne K, Martinez DR, Schäfer A, Alam SM, Wiehe K, Lu X, Parks R, Sutherland LL, Oguin TH, McDanal C, Perez LG, Mansouri K, Gobeil SMC, ... ... Baric RS, et al. The functions of SARS-CoV-2 neutralizing and infection-enhancing antibodies in vitro and in mice and nonhuman primates. Biorxiv : the Preprint Server For Biology. PMID 33442694 DOI: 10.1101/2020.12.31.424729  0.339
2021 Atyeo C, Slein MD, Fischinger S, Burke J, Schäfer A, Leist SR, Kuzmina NA, Mire C, Honko A, Johnson R, Storm N, Bernett M, Tong P, Zuo T, Lin J, ... ... Baric R, et al. Dissecting strategies to tune the therapeutic potential of SARS-CoV-2-specific monoclonal antibody CR3022. Jci Insight. 6. PMID 33427208 DOI: 10.1172/jci.insight.143129  0.336
2021 Schäfer A, Muecksch F, Lorenzi JCC, Leist SR, Cipolla M, Bournazos S, Schmidt F, Maison RM, Gazumyan A, Martinez DR, Baric RS, Robbiani DF, Hatziioannou T, Ravetch JV, Bieniasz PD, et al. Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo. The Journal of Experimental Medicine. 218. PMID 33211088 DOI: 10.1084/jem.20201993  0.655
2020 Xu F, Gao J, Bergmann S, Sims AC, Ashbrook DG, Baric RS, Cui Y, Jonsson CB, Li K, Williams RW, Schughart K, Lu L. Genetic Dissection of the Regulatory Mechanisms of in the Infected Mouse Lung. Frontiers in Immunology. 11: 607314. PMID 33488611 DOI: 10.3389/fimmu.2020.607314  0.35
2020 Shiakolas AR, Kramer KJ, Wrapp D, Richardson SI, Schäfer A, Wall S, Wang N, Janowska K, Pilewski KA, Venkat R, Parks R, Manamela NP, Raju N, Fechter EF, Holt CM, ... ... Baric RS, et al. Cross-reactive coronavirus antibodies with diverse epitope specificities and extra-neutralization functions. Biorxiv : the Preprint Server For Biology. PMID 33398266 DOI: 10.1101/2020.12.20.414748  0.33
2020 Ruis C, Lindesmith LC, Mallory ML, Brewer-Jensen PD, Bryant JM, Costantini V, Monit C, Vinjé J, Baric RS, Goldstein RA, Breuer J. Preadaptation of pandemic GII.4 noroviruses in unsampled virus reservoirs years before emergence. Virus Evolution. 6: veaa067. PMID 33381305 DOI: 10.1093/Ve/Veaa067  0.467
2020 Sun W, McCroskery S, Liu WC, Leist SR, Liu Y, Albrecht RA, Slamanig S, Oliva J, Amanat F, Schäfer A, Dinnon KH, Innis BL, García-Sastre A, Krammer F, Baric RS, et al. A Newcastle Disease Virus (NDV) Expressing a Membrane-Anchored Spike as a Cost-Effective Inactivated SARS-CoV-2 Vaccine. Vaccines. 8. PMID 33348607 DOI: 10.3390/vaccines8040771  0.311
2020 Sholukh AM, Fiore-Gartland A, Ford ES, Hou Y, Tse LV, Lempp FA, Kaiser H, Saint Germain R, Bossard E, Kee JJ, Diem K, Stuart AB, Rupert PB, Brock C, Buerger M, ... ... Baric RS, et al. Evaluation of SARS-CoV-2 neutralization assays for antibody monitoring in natural infection and vaccine trials. Medrxiv : the Preprint Server For Health Sciences. PMID 33330875 DOI: 10.1101/2020.12.07.20245431  0.317
2020 Verardi R, Lindesmith LC, Tsybovsky Y, Gorman J, Chuang GY, Edwards CE, Brewer-Jensen PD, Mallory ML, Ou L, Schön A, Shi W, Tully ES, Georgiou G, Baric RS, Kwong PD. Disulfide stabilization of human norovirus GI.1 virus-like particles focuses immune response toward blockade epitopes. Npj Vaccines. 5: 110. PMID 33318483 DOI: 10.1038/s41541-020-00260-w  0.341
2020 Puhl AC, Fritch EJ, Lane TR, Tse LV, Yount BL, Sacramento CQ, Tavella TA, Costa FTM, Weston S, Logue J, Frieman M, Premkumar L, Pearce KH, Hurst BL, Andrade CH, ... ... Baric RS, et al. Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine and Pyronaridine: In vitro Activity Against SARS-CoV-2 and Potential Mechanisms. Biorxiv : the Preprint Server For Biology. PMID 33299990 DOI: 10.1101/2020.12.01.407361  0.787
2020 Iserman C, Roden CA, Boerneke MA, Sealfon RSG, McLaughlin GA, Jungreis I, Fritch EJ, Hou YJ, Ekena J, Weidmann CA, Theesfeld CL, Kellis M, Troyanskaya OG, Baric RS, Sheahan TP, et al. Genomic RNA Elements Drive Phase Separation of the SARS-CoV-2 Nucleocapsid. Molecular Cell. PMID 33290746 DOI: 10.1016/j.molcel.2020.11.041  0.572
2020 Hörner C, Schürmann C, Auste A, Ebenig A, Muraleedharan S, Dinnon KH, Scholz T, Herrmann M, Schnierle BS, Baric RS, Mühlebach MD. A highly immunogenic and effective measles virus-based Th1-biased COVID-19 vaccine. Proceedings of the National Academy of Sciences of the United States of America. PMID 33257540 DOI: 10.1073/pnas.2014468117  0.35
2020 Rappazzo CG, Tse LV, Kaku CI, Wrapp D, Sakharkar M, Huang D, Deveau LM, Yockachonis TJ, Herbert AS, Battles MB, O'Brien CM, Brown ME, Geoghegan JC, Belk J, Peng L, ... ... Baric RS, et al. An Engineered Antibody with Broad Protective Efficacy in Murine Models of SARS and COVID-19. Biorxiv : the Preprint Server For Biology. PMID 33236009 DOI: 10.1101/2020.11.17.385500  0.316
2020 Sun W, Leist SR, McCroskery S, Liu Y, Slamanig S, Oliva J, Amanat F, Schäfer A, Dinnon KH, García-Sastre A, Krammer F, Baric RS, Palese P. Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as a live virus vaccine candidate. Ebiomedicine. 62: 103132. PMID 33232870 DOI: 10.1016/j.ebiom.2020.103132  0.38
2020 Hou YJ, Chiba S, Halfmann P, Ehre C, Kuroda M, Dinnon KH, Leist SR, Schäfer A, Nakajima N, Takahashi K, Lee RE, Mascenik TM, Graham R, Edwards CE, Tse LV, ... ... Baric RS, et al. SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo. Science (New York, N.Y.). PMID 33184236 DOI: 10.1126/science.abe8499  0.383
2020 Walls AC, Fiala B, Schäfer A, Wrenn S, Pham MN, Murphy M, Tse LV, Shehata L, O'Connor MA, Chen C, Navarro MJ, Miranda MC, Pettie D, Ravichandran R, Kraft JC, ... ... Baric RS, et al. Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for SARS-CoV-2. Cell. PMID 33160446 DOI: 10.1016/j.cell.2020.10.043  0.618
2020 Li W, Chen C, Drelich A, Martinez DR, Gralinski LE, Sun Z, Schäfer A, Kulkarni SS, Liu X, Leist SR, Zhelev DV, Zhang L, Kim YJ, Peterson EC, Conard A, ... ... Baric RS, et al. Rapid identification of a human antibody with high prophylactic and therapeutic efficacy in three animal models of SARS-CoV-2 infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 33139569 DOI: 10.1073/pnas.2010197117  0.361
2020 Katsura H, Sontake V, Tata A, Kobayashi Y, Edwards CE, Heaton BE, Konkimalla A, Asakura T, Mikami Y, Fritch EJ, Lee PJ, Heaton NS, Boucher RC, Randell SH, Baric RS, et al. Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction. Cell Stem Cell. PMID 33128895 DOI: 10.1016/j.stem.2020.10.005  0.336
2020 Edwards CE, Yount BL, Graham RL, Leist SR, Hou YJ, Dinnon KH, Sims AC, Swanstrom J, Gully K, Scobey TD, Cooley MR, Currie CG, Randell SH, Baric RS. Swine acute diarrhea syndrome coronavirus replication in primary human cells reveals potential susceptibility to infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 33046644 DOI: 10.1073/pnas.2001046117  0.351
2020 Leist SR, Dinnon KH, Schäfer A, Tse LV, Okuda K, Hou YJ, West A, Edwards CE, Sanders W, Fritch EJ, Gully KL, Scobey T, Brown AJ, Sheahan TP, Moorman NJ, ... ... Baric RS, et al. A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice. Cell. PMID 33031744 DOI: 10.1016/j.cell.2020.09.050  0.654
2020 Martinez DR, Yount B, Nivarthi U, Munt JE, Delacruz MJ, Whitehead SS, Durbin AP, de Silva AM, Baric RS. Antigenic Variation of the Dengue Virus 2 Genotypes Impacts the Neutralization Activity of Human Antibodies in Vaccinees. Cell Reports. 33: 108226. PMID 33027653 DOI: 10.1016/j.celrep.2020.108226  0.327
2020 Hou YJ, Chiba S, Halfmann P, Ehre C, Kuroda M, Dinnon KH, Leist SR, Schäfer A, Nakajima N, Takahashi K, Lee RE, Mascenik TM, Edwards CE, Tse LV, Boucher RC, ... ... Baric RS, et al. SARS-CoV-2 D614G Variant Exhibits Enhanced Replication and Earlier Transmission . Biorxiv : the Preprint Server For Biology. PMID 33024969 DOI: 10.1101/2020.09.28.317685  0.408
2020 Jones BE, Brown-Augsburger PL, Corbett KS, Westendorf K, Davies J, Cujec TP, Wiethoff CM, Blackbourne JL, Heinz BA, Foster D, Higgs RE, Balasubramaniam D, Wang L, Bidshahri R, Kraft L, ... ... Baric RS, et al. LY-CoV555, a rapidly isolated potent neutralizing antibody, provides protection in a non-human primate model of SARS-CoV-2 infection. Biorxiv : the Preprint Server For Biology. PMID 33024963 DOI: 10.1101/2020.09.30.318972  0.317
2020 Rydyznski Moderbacher C, Ramirez SI, Dan JM, Grifoni A, Hastie KM, Weiskopf D, Belanger S, Abbott RK, Kim C, Choi J, Kato Y, Crotty EG, Kim C, Rawlings SA, Mateus J, ... ... Baric R, et al. Antigen-Specific Adaptive Immunity to SARS-CoV-2 in Acute COVID-19 and Associations with Age and Disease Severity. Cell. PMID 33010815 DOI: 10.1016/J.Cell.2020.09.038  0.317
2020 Graham JB, Swarts JL, Leist SR, Schäfer A, Menachery VD, Gralinski LE, Jeng S, Miller DR, Mooney MA, McWeeney SK, Ferris MT, de Villena FP, Heise MT, Baric RS, Lund JM. Baseline T cell immune phenotypes predict virologic and disease control upon SARS-CoV infection. Biorxiv : the Preprint Server For Biology. PMID 32995791 DOI: 10.1101/2020.09.21.306837  0.304
2020 Schäfer A, Muecksch F, Lorenzi JCC, Leist SR, Cipolla M, Bournazos S, Schmidt F, Gazumyan A, Baric RS, Robbiani DF, Hatziioannou T, Ravetch JV, Bieniasz PD, Nussenzweig MC, Sheahan TP. Antibody potency, effector function and combinations in protection from SARS-CoV-2 infection . Biorxiv : the Preprint Server For Biology. PMID 32995782 DOI: 10.1101/2020.09.15.298067  0.657
2020 Wahl A, Gralinski L, Johnson C, Yao W, Kovarova M, Dinnon K, Liu H, Madden V, Krzystek H, De C, White K, Schäfer A, Zaman T, Leist S, Grant P, ... ... Baric R, et al. Acute SARS-CoV-2 Infection is Highly Cytopathic, Elicits a Robust Innate Immune Response and is Efficiently Prevented by EIDD-2801. Research Square. PMID 32995766 DOI: 10.21203/rs.3.rs-80404/v1  0.356
2020 Muñoz-Fontela C, Dowling WE, Funnell SGP, Gsell PS, Balta XR, Albrecht RA, Andersen H, Baric RS, Carroll MW, Cavaleri M, Qin C, Crozier I, Dallmeier K, de Waal L, de Wit E, et al. Animal models for COVID-19. Nature. PMID 32967005 DOI: 10.1038/s41586-020-2787-6  0.627
2020 Li W, Schäfer A, Kulkarni SS, Liu X, Martinez DR, Chen C, Sun Z, Leist SR, Drelich A, Zhang L, Ura ML, Berezuk A, Chittori S, Leopold K, Mannar D, ... ... Baric RS, et al. High Potency of a Bivalent Human V Domain in SARS-CoV-2 Animal Models. Cell. PMID 32941803 DOI: 10.1016/J.Cell.2020.09.007  0.39
2020 Hassan AO, Kafai NM, Dmitriev IP, Fox JM, Smith BK, Harvey IB, Chen RE, Winkler ES, Wessel AW, Case JB, Kashentseva E, McCune BT, Bailey AL, Zhao H, VanBlargan LA, ... ... Baric RS, et al. A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2. Cell. PMID 32931734 DOI: 10.1016/J.Cell.2020.08.026  0.493
2020 Mallory ML, Lindesmith LC, Brewer-Jensen PD, Graham RL, Baric RS. Bile Facilitates Human Norovirus Interactions with Diverse Histoblood Group Antigens, Compensating for Capsid Microvariation Observed in 2016-2017 GII.2 Strains. Viruses. 12. PMID 32899556 DOI: 10.3390/V12090989  0.424
2020 Olival KJ, Cryan PM, Amman BR, Baric RS, Blehert DS, Brook CE, Calisher CH, Castle KT, Coleman JTH, Daszak P, Epstein JH, Field H, Frick WF, Gilbert AT, Hayman DTS, et al. Possibility for reverse zoonotic transmission of SARS-CoV-2 to free-ranging wildlife: A case study of bats. Plos Pathogens. 16: e1008758. PMID 32881980 DOI: 10.1371/Journal.Ppat.1008758  0.392
2020 Dinnon KH, Leist SR, Schäfer A, Edwards CE, Martinez DR, Montgomery SA, West A, Yount BL, Hou YJ, Adams LE, Gully KL, Brown AJ, Huang E, Bryant MD, Choong IC, ... ... Baric RS, et al. A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures. Nature. PMID 32854108 DOI: 10.1038/S41586-020-2708-8  0.698
2020 Walls AC, Fiala B, Schäfer A, Wrenn S, Pham MN, Murphy M, Tse LV, Shehata L, O'Connor MA, Chen C, Navarro MJ, Miranda MC, Pettie D, Ravichandran R, Kraft JC, ... ... Baric RS, et al. Elicitation of potent neutralizing antibody responses by designed protein nanoparticle vaccines for SARS-CoV-2. Biorxiv : the Preprint Server For Biology. PMID 32817941 DOI: 10.1101/2020.08.11.247395  0.623
2020 Corbett KS, Edwards DK, Leist SR, Abiona OM, Boyoglu-Barnum S, Gillespie RA, Himansu S, Schäfer A, Ziwawo CT, DiPiazza AT, Dinnon KH, Elbashir SM, Shaw CA, Woods A, Fritch EJ, ... ... Baric RS, et al. SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness. Nature. PMID 32756549 DOI: 10.1038/S41586-020-2622-0  0.41
2020 Zhang K, Zheludev IN, Hagey RJ, Wu MT, Haslecker R, Hou YJ, Kretsch R, Pintilie GD, Rangan R, Kladwang W, Li S, Pham EA, Bernardin-Souibgui C, Baric RS, Sheahan TP, et al. Cryo-electron Microscopy and Exploratory Antisense Targeting of the 28-kDa Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome. Biorxiv : the Preprint Server For Biology. PMID 32743589 DOI: 10.1101/2020.07.18.209270  0.608
2020 Sun W, Leist SR, McCroskery S, Liu Y, Slamanig S, Oliva J, Amanat F, Schaefer A, Dinnon K, Garcia-Sastre A, Krammer F, Baric RS, Palese P. Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as vaccine candidate. Biorxiv : the Preprint Server For Biology. PMID 32743571 DOI: 10.1101/2020.07.26.221861  0.351
2020 Mercado NB, Zahn R, Wegmann F, Loos C, Chandrashekar A, Yu J, Liu J, Peter L, McMahan K, Tostanoski LH, He X, Martinez DR, Rutten L, Bos R, van Manen D, ... ... Baric RS, et al. Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques. Nature. PMID 32731257 DOI: 10.1038/S41586-020-2607-Z  0.389
2020 Corbett KS, Flynn B, Foulds KE, Francica JR, Boyoglu-Barnum S, Werner AP, Flach B, O'Connell S, Bock KW, Minai M, Nagata BM, Andersen H, Martinez DR, Noe AT, Douek N, ... ... Baric RS, et al. Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates. The New England Journal of Medicine. PMID 32722908 DOI: 10.1056/Nejmoa2024671  0.398
2020 Zost SJ, Gilchuk P, Case JB, Binshtein E, Chen RE, Nkolola JP, Schäfer A, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Martinez DR, Williamson LE, Chen EC, ... ... Baric RS, et al. Potently neutralizing and protective human antibodies against SARS-CoV-2. Nature. PMID 32668443 DOI: 10.1038/S41586-020-2548-6  0.476
2020 Pruijssers AJ, George AS, Schäfer A, Leist SR, Gralinksi LE, Dinnon KH, Yount BL, Agostini ML, Stevens LJ, Chappell JD, Lu X, Hughes TM, Gully K, Martinez DR, Brown AJ, ... ... Baric RS, et al. Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice. Cell Reports. 107940. PMID 32668216 DOI: 10.1016/J.Celrep.2020.107940  0.693
2020 Menachery VD, Yount BL, Debbink K, Agnihothram S, Gralinski LE, Plante JA, Graham RL, Scobey T, Ge XY, Donaldson EF, Randell SH, Lanzavecchia A, Marasco WA, Shi ZL, Baric RS. Author Correction: A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence. Nature Medicine. 26: 1146. PMID 32661400 DOI: 10.1038/S41591-020-0924-2  0.759
2020 Zost SJ, Gilchuk P, Chen RE, Case JB, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Chen EC, Binshtein E, Shrihari S, Ostrowski M, Chu HY, Didier JE, ... ... Baric RS, et al. Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein. Nature Medicine. PMID 32651581 DOI: 10.1038/S41591-020-0998-X  0.458
2020 Iserman C, Roden C, Boerneke M, Sealfon R, McLaughlin G, Jungreis I, Park C, Boppana A, Fritch E, Hou YJ, Theesfeld C, Troyanskaya OG, Baric RS, Sheahan TP, Weeks K, et al. Specific viral RNA drives the SARS CoV-2 nucleocapsid to phase separate. Biorxiv : the Preprint Server For Biology. PMID 32587965 DOI: 10.1101/2020.06.11.147199  0.597
2020 Sun Z, Chen C, Li W, Martinez DR, Drelich A, Baek DS, Liu X, Mellors JW, Tseng CT, Baric RS, Dimitrov DS. Potent neutralization of SARS-CoV-2 by human antibody heavy-chain variable domains isolated from a large library with a new stable scaffold. Mabs. 12: 1778435. PMID 32544372 DOI: 10.1080/19420862.2020.1778435  0.376
2020 Wec AZ, Wrapp D, Herbert AS, Maurer DP, Haslwanter D, Sakharkar M, Jangra RK, Dieterle ME, Lilov A, Huang D, Tse LV, Johnson NV, Hsieh CL, Wang N, Nett JH, ... ... Baric RS, et al. Broad neutralization of SARS-related viruses by human monoclonal antibodies. Science (New York, N.Y.). PMID 32540900 DOI: 10.1126/Science.Abc7424  0.441
2020 Premkumar L, Segovia-Chumbez B, Jadi R, Martinez DR, Raut R, Markmann A, Cornaby C, Bartelt L, Weiss S, Park Y, Edwards CE, Weimer E, Scherer EM, Rouphael N, Edupuganti S, ... ... Baric RS, et al. The receptor binding domain of the viral spike protein is an immunodominant and highly specific target of antibodies in SARS-CoV-2 patients. Science Immunology. 5. PMID 32527802 DOI: 10.1126/Sciimmunol.Abc8413  0.459
2020 Hou YJ, Okuda K, Edwards CE, Martinez DR, Asakura T, Dinnon KH, Kato T, Lee RE, Yount BL, Mascenik TM, Chen G, Olivier KN, Ghio A, Tse LV, Leist SR, ... ... Baric RS, et al. SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract. Cell. PMID 32526206 DOI: 10.1016/J.Cell.2020.05.042  0.483
2020 Jiang RD, Liu MQ, Chen Y, Shan C, Zhou YW, Shen XR, Li Q, Zhang L, Zhu Y, Si HR, Wang Q, Min J, Wang X, Zhang W, Li B, ... ... Baric RS, et al. Pathogenesis of SARS-CoV-2 in Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2. Cell. PMID 32516571 DOI: 10.1016/J.Cell.2020.05.027  0.44
2020 Premkumar L, Segovia-Chumbez B, Jadi R, Martinez DR, Raut R, Markmann A, Cornaby C, Bartelt L, Weiss S, Park Y, Edwards CE, Weimer E, Scherer EM, Roupael N, Edupuganti S, ... ... Baric RS, et al. The RBD Of The Spike Protein Of SARS-Group Coronaviruses Is A Highly Specific Target Of SARS-CoV-2 Antibodies But Not Other Pathogenic Human and Animal Coronavirus Antibodies. Medrxiv : the Preprint Server For Health Sciences. PMID 32511572 DOI: 10.1101/2020.05.06.20093377  0.362
2020 Zost SJ, Gilchuk P, Chen RE, Case JB, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Chen EC, Binshtein E, Shrihari S, Ostrowski M, Chu HY, Didier JE, ... ... Baric RS, et al. Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein. Biorxiv : the Preprint Server For Biology. PMID 32511414 DOI: 10.1101/2020.05.12.091462  0.35
2020 Li W, Drelich A, Martinez DR, Gralinski L, Chen C, Sun Z, Liu X, Zhelev D, Zhang L, Peterson EC, Conard A, Mellors JW, Tseng CT, Baric RS, Dimitrov DS. Potent neutralization of SARS-CoV-2 in vitro and in an animal model by a human monoclonal antibody. Biorxiv : the Preprint Server For Biology. PMID 32511413 DOI: 10.1101/2020.05.13.093088  0.345
2020 Zost SJ, Gilchuk P, Case JB, Binshtein E, Chen RE, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Williamson LE, Chen EC, Jones T, Day S, Myers L, ... ... Baric RS, et al. Potently neutralizing human antibodies that block SARS-CoV-2 receptor binding and protect animals. Biorxiv : the Preprint Server For Biology. PMID 32511409 DOI: 10.1101/2020.05.22.111005  0.368
2020 Dinnon KH, Leist SR, Schäfer A, Edwards CE, Martinez DR, Montgomery SA, West A, Yount BL, Hou YJ, Adams LE, Gully KL, Brown AJ, Huang E, Bryant MD, Choong IC, ... ... Baric RS, et al. A mouse-adapted SARS-CoV-2 model for the evaluation of COVID-19 medical countermeasures. Biorxiv : the Preprint Server For Biology. PMID 32511406 DOI: 10.1101/2020.05.06.081497  0.668
2020 Pruijssers AJ, George AS, Schäfer A, Leist SR, Gralinksi LE, Dinnon KH, Yount BL, Agostini ML, Stevens LJ, Chappell JD, Lu X, Hughes TM, Gully K, Martinez DR, Brown AJ, ... ... Baric RS, et al. Remdesivir potently inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice. Biorxiv : the Preprint Server For Biology. PMID 32511392 DOI: 10.1101/2020.04.27.064279  0.666
2020 Wec AZ, Wrapp D, Herbert AS, Maurer D, Haslwanter D, Sakharkar M, Jangra RK, Dieterle ME, Lilov A, Huang D, Tse LV, Johnson NV, Hsieh CL, Wang N, Nett JH, ... ... Baric RS, et al. Broad sarbecovirus neutralizing antibodies define a key site of vulnerability on the SARS-CoV-2 spike protein. Biorxiv : the Preprint Server For Biology. PMID 32511337 DOI: 10.1101/2020.05.15.096511  0.333
2020 Lambert PH, Ambrosino DM, Andersen SR, Baric RS, Black SB, Chen RT, Dekker CL, Didierlaurent AM, Graham BS, Martin SD, Molrine DC, Perlman S, Picard-Fraser PA, Pollard AJ, Qin C, et al. Consensus summary report for CEPI/BC March 12-13, 2020 meeting: Assessment of risk of disease enhancement with COVID-19 vaccines. Vaccine. PMID 32507409 DOI: 10.1016/J.Vaccine.2020.05.064  0.39
2020 Chandrashekar A, Liu J, Martinot AJ, McMahan K, Mercado NB, Peter L, Tostanoski LH, Yu J, Maliga Z, Nekorchuk M, Busman-Sahay K, Terry M, Wrijil LM, Ducat S, Martinez DR, ... ... Baric RS, et al. SARS-CoV-2 infection protects against rechallenge in rhesus macaques. Science (New York, N.Y.). PMID 32434946 DOI: 10.1126/Science.Abc4776  0.446
2020 Yu J, Tostanoski LH, Peter L, Mercado NB, McMahan K, Mahrokhian SH, Nkolola JP, Liu J, Li Z, Chandrashekar A, Martinez DR, Loos C, Atyeo C, Fischinger S, Burke JS, ... ... Baric RS, et al. DNA vaccine protection against SARS-CoV-2 in rhesus macaques. Science (New York, N.Y.). PMID 32434945 DOI: 10.1126/Science.Abc6284  0.42
2020 Young E, Carnahan RH, Andrade DV, Kose N, Nargi RS, Fritch EJ, Munt JE, Doyle MP, White L, Baric TJ, Stoops M, DeSilva A, Tse LV, Martinez DR, Zhu D, ... ... Baric RS, et al. Identification of Dengue Virus Serotype 3 Specific Antigenic Sites Targeted by Neutralizing Human Antibodies. Cell Host & Microbe. 27: 710-724.e7. PMID 32407709 DOI: 10.1016/J.Chom.2020.04.007  0.454
2020 Graham RL, Baric RS. SARS-CoV-2: Combating Coronavirus Emergence. Immunity. PMID 32392464 DOI: 10.1016/J.Immuni.2020.04.016  0.407
2020 Tse LV, Meganck RM, Graham RL, Baric RS. The Current and Future State of Vaccines, Antivirals and Gene Therapies Against Emerging Coronaviruses. Frontiers in Microbiology. 11: 658. PMID 32390971 DOI: 10.3389/Fmicb.2020.00658  0.424
2020 Noll KE, Whitmore AC, West A, McCarthy MK, Morrison CR, Plante KS, Hampton BK, Kollmus H, Pilzner C, Leist SR, Gralinski LE, Menachery VD, Schäfer A, Miller D, Shaw G, ... ... Baric RS, et al. Complex Genetic Architecture Underlies Regulation of Influenza-A-Virus-Specific Antibody Responses in the Collaborative Cross. Cell Reports. 31: 107587. PMID 32348764 DOI: 10.1016/J.Celrep.2020.107587  0.427
2020 Lindesmith LC, Brewer-Jensen PD, Mallory ML, Jensen K, Yount BL, Costantini V, Collins MH, Edwards CE, Sheahan TP, Vinjé J, Baric RS. Virus-host interactions between non-secretors and human norovirus. Cellular and Molecular Gastroenterology and Hepatology. PMID 32289501 DOI: 10.1016/J.Jcmgh.2020.03.006  0.708
2020 Sheahan TP, Sims AC, Zhou S, Graham RL, Pruijssers AJ, Agostini ML, Leist SR, Schäfer A, Dinnon KH, Stevens LJ, Chappell JD, Lu X, Hughes TM, George AS, Hill CS, ... ... Baric RS, et al. An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice. Science Translational Medicine. PMID 32253226 DOI: 10.1126/Scitranslmed.Abb5883  0.649
2020 Nivarthi UK, Tu HA, Delacruz MJ, Swanstrom J, Patel B, Durbin AP, Whitehead SS, Pierce KK, Kirkpatrick BD, Baric RS, Nguyen N, Emerling DE, de Silva AM, Diehl SA. Corrigendum to ''Longitudinal analysis of acute and convalescent B cell responses in a human primary dengue serotype 2 infection model'' [EBioMedicine 41 (2019) 465-478]. Ebiomedicine. 54: 102708. PMID 32251996 DOI: 10.1016/J.Ebiom.2020.102708  0.356
2020 Graziano VR, Walker FC, Kennedy EA, Wei J, Ettayebi K, Strine MS, Filler RB, Hassan E, Hsieh LL, Kim AS, Kolawole AO, Wobus CE, Lindesmith LC, Baric RS, Estes MK, et al. CD300lf is the primary physiologic receptor of murine norovirus but not human norovirus. Plos Pathogens. 16: e1008242. PMID 32251490 DOI: 10.1371/Journal.Ppat.1008242  0.414
2020 Gorbalenya AE, Baker SC, Baric RS, Groot RJd, Drosten C, Gulyaeva AA, Haagmans BL, Lauber C, Leontovich AM, Neuman BW, Penzar D, Perlman S, Poon LLM, Samborskiy DV, Sidorov IA, et al. The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2 Nature Microbiology. 5: 536-544. PMID 32123347 DOI: 10.1038/S41564-020-0695-Z  0.308
2020 Sheahan TP, Sims AC, Leist SR, Schäfer A, Won J, Brown AJ, Montgomery SA, Hogg A, Babusis D, Clarke MO, Spahn JE, Bauer L, Sellers S, Porter D, Feng JY, ... ... Baric RS, et al. Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV. Nature Communications. 11: 222. PMID 31924756 DOI: 10.1038/S41467-019-13940-6  0.643
2019 Menachery VD, Dinnon KH, Yount BL, McAnarney ET, Gralinski LE, Hale A, Graham RL, Scobey T, Anthony SJ, Wang L, Graham B, Randell SH, Lipkin WI, Baric RS. Trypsin treatment unlocks barrier for zoonotic bat coronaviruses infection. Journal of Virology. PMID 31801868 DOI: 10.1128/Jvi.01774-19  0.34
2019 Andrade DV, Warnes C, Young E, Katzelnick LC, Balmaseda A, de Silva AM, Baric RS, Harris E. Tracking the polyclonal neutralizing antibody response to a dengue virus serotype 1 type-specific epitope across two populations in Asia and the Americas. Scientific Reports. 9: 16258. PMID 31700029 DOI: 10.1038/S41598-019-52511-Z  0.393
2019 Mateo R, Lindesmith LC, Garg SJ, Gottlieb K, Lin K, Said S, Leon JS, Sims AC, Weber DJ, Baric RS, Tucker SN, Taylor DN. Production and Clinical Evaluation of Norwalk GI.1 Virus Lot 001-09NV in Norovirus Vaccine Development. The Journal of Infectious Diseases. PMID 31628848 DOI: 10.1093/Infdis/Jiz540  0.431
2019 Graham JB, Swarts JL, Menachery VD, Gralinski LE, Schäfer A, Plante KS, Morrison CR, Voss KM, Green R, Choonoo G, Jeng S, Miller DR, Mooney MA, McWeeney SK, Ferris MT, ... ... Baric RS, et al. Immune predictors of mortality following RNA virus infection. The Journal of Infectious Diseases. PMID 31621854 DOI: 10.1093/Infdis/Jiz531  0.361
2019 Mitchell HD, Eisfeld AJ, Stratton KG, Heller NC, Bramer LM, Wen J, McDermott JE, Gralinski LE, Sims AC, Le MQ, Baric RS, Kawaoka Y, Waters KM. The Role of EGFR in Influenza Pathogenicity: Multiple Network-Based Approaches to Identify a Key Regulator of Non-lethal Infections. Frontiers in Cell and Developmental Biology. 7: 200. PMID 31616667 DOI: 10.3389/Fcell.2019.00200  0.446
2019 Agostini ML, Pruijssers AJ, Chappell JD, Gribble J, Lu X, Andres EL, Bluemling GR, Lockwood MA, Sheahan TP, Sims AC, Natchus MG, Saindane M, Kolykhalov AA, Painter GR, Baric RS, et al. Small molecule antiviral β-D--hydroxycytidine inhibits a proofreading-intact coronavirus with a high genetic barrier to resistance. Journal of Virology. PMID 31578288 DOI: 10.1128/Jvi.01348-19  0.689
2019 Zimmerman MG, Bowen JR, McDonald CE, Young E, Baric RS, Pulendran B, Suthar MS. STAT5: A Target of Antagonism by Neurotropic Flaviviruses. Journal of Virology. PMID 31534033 DOI: 10.1128/Jvi.00665-19  0.321
2019 Gallichotte EN, Young EF, Baric TJ, Yount BL, Metz SW, Begley MC, de Silva AM, Baric RS. Role of Zika Virus Envelope Protein Domain III as a Target of Human Neutralizing Antibodies. Mbio. 10. PMID 31530669 DOI: 10.1128/Mbio.01485-19  0.466
2019 Esseili MA, Gao X, Boley P, Hou Y, Saif LJ, Brewer-Jensen P, Lindesmith LC, Baric RS, Atmar RL, Wang Q. Human Norovirus Histo-Blood Group Antigen (HBGA) Binding Sites Mediate the Virus Specific Interactions with Lettuce Carbohydrates. Viruses. 11. PMID 31500340 DOI: 10.3390/V11090833  0.374
2019 Leist SR, Jensen KL, Baric RS, Sheahan TP. Increasing the translation of mouse models of MERS coronavirus pathogenesis through kinetic hematological analysis. Plos One. 14: e0220126. PMID 31339932 DOI: 10.1371/Journal.Pone.0220126  0.694
2019 Brown AJ, Won JJ, Graham RL, Dinnon KH, Sims AC, Feng JY, Cihlar T, Denison MR, Baric RS, Sheahan TP. Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase. Antiviral Research. 104541. PMID 31233808 DOI: 10.1016/J.Antiviral.2019.104541  0.671
2019 Lindesmith LC, McDaniel JR, Changela A, Verardi R, Kerr SA, Costantini V, Brewer-Jensen PD, Mallory ML, Voss WN, Boutz DR, Blazeck JJ, Ippolito GC, Vinje J, Kwong PD, Georgiou G, ... Baric RS, et al. Sera Antibody Repertoire Analyses Reveal Mechanisms of Broad and Pandemic Strain Neutralizing Responses after Human Norovirus Vaccination. Immunity. 50: 1530-1541.e8. PMID 31216462 DOI: 10.1016/J.Immuni.2019.05.007  0.344
2019 Carbaugh DL, Baric RS, Lazear HM. Envelope protein glycosylation mediates Zika virus pathogenesis. Journal of Virology. PMID 30944176 DOI: 10.1128/JVI.00113-19  0.374
2019 Comar CE, Goldstein SA, Li Y, Yount B, Baric RS, Weiss SR. Antagonism of dsRNA-Induced Innate Immune Pathways by NS4a and NS4b Accessory Proteins during MERS Coronavirus Infection. Mbio. 10. PMID 30914508 DOI: 10.1128/Mbio.00319-19  0.492
2019 Swanstrom JA, Nivarthi UK, Patel B, Delacruz MJ, Yount B, Widman DG, Durbin AP, Whitehead SS, de Silva AM, Baric RS. Beyond Neutralizing Antibody Levels: The Epitope Specificity of Antibodies Induced by NIH Monovalent Dengue Virus Vaccines. The Journal of Infectious Diseases. PMID 30895307 DOI: 10.1093/Infdis/Jiz109  0.448
2019 Nivarthi UK, Tu HA, Delacruz MJ, Swanstrom J, Patel B, Durbin AP, Whitehead SS, Pierce KK, Kirkpatrick BD, Baric RS, Nguyen N, Emerling DE, de Silva AM, Diehl SA. Longitudinal analysis of acute and convalescent B cell responses in a human primary dengue serotype 2 infection model. Ebiomedicine. PMID 30857944 DOI: 10.1016/J.Ebiom.2019.02.060  0.398
2019 Mallory ML, Lindesmith LC, Graham RL, Baric RS. GII.4 Human Norovirus: Surveying the Antigenic Landscape. Viruses. 11. PMID 30791623 DOI: 10.3390/V11020177  0.472
2018 van Doremalen N, Schäfer A, Menachery VD, Letko M, Bushmaker T, Fischer RJ, Figueroa DM, Hanley PW, Saturday G, Baric RS, Munster VJ. SARS-Like Coronavirus WIV1-CoV Does Not Replicate in Egyptian Fruit Bats (). Viruses. 10. PMID 30572566 DOI: 10.3390/V10120727  0.342
2018 Sheahan TP, Baric RS. Is regulation preventing the development of therapeutics that may prevent future coronavirus pandemics? Future Virology. 13: 143-146. PMID 30546388 DOI: 10.2217/Fvl-2017-0143  0.557
2018 Fowler AM, Tang WW, Young MP, Mamidi A, Viramontes KM, McCauley MD, Carlin AF, Schooley RT, Swanstrom J, Baric RS, Govero J, Diamond MS, Shresta S. Maternally Acquired Zika Antibodies Enhance Dengue Disease Severity in Mice. Cell Host & Microbe. 24: 743-750.e5. PMID 30439343 DOI: 10.1016/J.Chom.2018.09.015  0.439
2018 Graham RL, Deming DJ, Deming ME, Yount BL, Baric RS. Evaluation of a recombination-resistant coronavirus as a broadly applicable, rapidly implementable vaccine platform. Communications Biology. 1: 179. PMID 30393776 DOI: 10.1038/s42003-018-0175-7  0.724
2018 Gallichotte EN, Baric TJ, Nivarthi U, Delacruz MJ, Graham R, Widman DG, Yount BL, Durbin AP, Whitehead SS, de Silva AM, Baric RS. Genetic Variation between Dengue Virus Type 4 Strains Impacts Human Antibody Binding and Neutralization. Cell Reports. 25: 1214-1224. PMID 30380413 DOI: 10.1016/J.Celrep.2018.10.006  0.486
2018 Lindesmith LC, Brewer-Jensen PD, Mallory ML, Yount B, Collins MH, Debbink K, Graham RL, Baric RS. Human norovirus epitope D plasticity allows escape from antibody immunity without loss of capacity for binding cellular ligands. Journal of Virology. PMID 30355694 DOI: 10.1128/Jvi.01813-18  0.719
2018 Gralinski LE, Sheahan TP, Morrison TE, Menachery VD, Jensen K, Leist SR, Whitmore A, Heise MT, Baric RS. Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis. Mbio. 9. PMID 30301856 DOI: 10.1128/Mbio.01753-18  0.689
2018 Zheng Y, Shang J, Yang Y, Liu C, Wan Y, Geng Q, Wang M, Baric R, Li F. Lysosomal proteases are a determinant of coronavirus tropism. Journal of Virology. PMID 30258004 DOI: 10.1128/Jvi.01504-18  0.322
2018 Leist SR, Baric RS. Giving the Genes a Shuffle: Using Natural Variation to Understand Host Genetic Contributions to Viral Infections. Trends in Genetics : Tig. PMID 30131185 DOI: 10.1016/J.Tig.2018.07.005  0.405
2018 Nakagawa K, Narayanan K, Wada M, Popov VL, Cajimat M, Baric RS, Makino S. The endonucleolytic RNA cleavage function of nsp1 of Middle East respiratory syndrome coronavirus promotes the production of infectious virus particles in specific human cell lines. Journal of Virology. PMID 30111568 DOI: 10.1128/Jvi.01157-18  0.457
2018 Cockrell AS, Leist SR, Douglas MG, Baric RS. Modeling pathogenesis of emergent and pre-emergent human coronaviruses in mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 30043100 DOI: 10.1007/S00335-018-9760-9  0.431
2018 Cockrell AS, Johnson JC, Moore IN, Liu DX, Bock KW, Douglas MG, Graham RL, Solomon J, Torzewski L, Bartos C, Hart R, Baric RS, Johnson RF. A spike-modified Middle East respiratory syndrome coronavirus (MERS-CoV) infectious clone elicits mild respiratory disease in infected rhesus macaques. Scientific Reports. 8: 10727. PMID 30013082 DOI: 10.1038/S41598-018-28900-1  0.445
2018 Gallichotte EN, Baric RS, de Silva AM. The Molecular Specificity of the Human Antibody Response to Dengue Virus Infections. Advances in Experimental Medicine and Biology. 1062: 63-76. PMID 29845525 DOI: 10.1007/978-981-10-8727-1_5  0.459
2018 Mallory ML, Lindesmith LC, Baric RS. Vaccination-Induced Herd Immunity: Successes and Challenges. The Journal of Allergy and Clinical Immunology. PMID 29803799 DOI: 10.1016/J.Jaci.2018.05.007  0.341
2018 Swanstrom JA, Henein S, Plante JA, Yount BL, Widman DG, Gallichotte EN, Dean HJ, Osorio JE, Partidos CD, de Silva AM, Baric RS. Analyzing the Human Serum Antibody Responses to a Live Attenuated Tetravalent Dengue Vaccine Candidate. The Journal of Infectious Diseases. 217: 1932-1941. PMID 29800370 DOI: 10.1093/Infdis/Jiy063  0.442
2018 Shin JS, Jung E, Kim M, Baric RS, Go YY. Saracatinib Inhibits Middle East Respiratory Syndrome-Coronavirus Replication In Vitro. Viruses. 10. PMID 29795047 DOI: 10.3390/V10060283  0.41
2018 Kocher JF, Lindesmith LC, Debbink K, Beall A, Mallory ML, Yount BL, Graham RL, Huynh J, Gates JE, Donaldson EF, Baric RS. Bat Caliciviruses and Human Noroviruses Are Antigenically Similar and Have Overlapping Histo-Blood Group Antigen Binding Profiles. Mbio. 9. PMID 29789360 DOI: 10.1128/Mbio.00869-18  0.817
2018 Gorman MJ, Caine EA, Zaitsev K, Begley MC, Weger-Lucarelli J, Uccellini MB, Tripathi S, Morrison J, Yount BL, Dinnon KH, Rückert C, Young MC, Zhu Z, Robertson SJ, McNally KL, ... ... Baric RS, et al. An Immunocompetent Mouse Model of Zika Virus Infection. Cell Host & Microbe. 23: 672-685.e6. PMID 29746837 DOI: 10.1016/J.Chom.2018.04.003  0.442
2018 Agnihothram S, Menachery VD, Yount BL, Lindesmith LC, Scobey T, Whitmore A, Schäfer A, Heise MT, Baric RS. Development of a Broadly Accessible VEE Replicon Particle Vaccine Platform. Journal of Virology. PMID 29540599 DOI: 10.1128/Jvi.00027-18  0.421
2018 Agostini ML, Andres EL, Sims AC, Graham RL, Sheahan TP, Lu X, Smith EC, Case JB, Feng JY, Jordan R, Ray AS, Cihlar T, Siegel D, Mackman RL, Clarke MO, ... Baric RS, et al. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease. Mbio. 9. PMID 29511076 DOI: 10.1128/Mbio.00221-18  0.687
2018 Gallichotte EN, Baric TJ, Yount BL, Widman DG, Durbin A, Whitehead S, Baric RS, de Silva AM. Human dengue virus serotype 2 neutralizing antibodies target two distinct quaternary epitopes. Plos Pathogens. 14: e1006934. PMID 29481552 DOI: 10.1371/Journal.Ppat.1006934  0.492
2018 Lindesmith LC, Mallory ML, Debbink K, Donaldson EF, Brewer-Jensen PD, Swann EW, Sheahan TP, Graham RL, Beltramello M, Corti D, Lanzavecchia A, Baric RS. Conformational Occlusion of Blockade Antibody Epitopes, a Novel Mechanism of GII.4 Human Norovirus Immune Evasion. Msphere. 3. PMID 29435493 DOI: 10.1128/mSphere.00518-17  0.813
2018 Menachery VD, Schäfer A, Burnum-Johnson KE, Mitchell HD, Eisfeld AJ, Walters KB, Nicora CD, Purvine SO, Casey CP, Monroe ME, Weitz KK, Stratton KG, Webb-Robertson BM, Gralinski LE, Metz TO, ... ... Baric RS, et al. MERS-CoV and H5N1 influenza virus antagonize antigen presentation by altering the epigenetic landscape. Proceedings of the National Academy of Sciences of the United States of America. PMID 29339515 DOI: 10.1073/Pnas.1706928115  0.358
2017 Lindesmith LC, Brewer-Jensen PD, Mallory ML, Debbink K, Swann EW, Vinjé J, Baric RS. Antigenic characterization of a novel recombinant GII.P16-GII.4 Sydney norovirus strain with minor sequence variation leading to antibody escape. The Journal of Infectious Diseases. PMID 29281104 DOI: 10.1093/Infdis/Jix651  0.731
2017 Douglas MG, Kocher JF, Scobey T, Baric RS, Cockrell AS. Adaptive evolution influences the infectious dose of MERS-CoV necessary to achieve severe respiratory disease. Virology. PMID 29277291 DOI: 10.1016/J.Virol.2017.12.006  0.4
2017 Widman DG, Young E, Nivarthi U, Swanstrom JA, Royal SR, Yount BL, Debbink K, Begley M, Marcet S, Durbin A, de Silva AM, Messer WB, Baric RS. Transplantation of a quaternary structure neutralizing antibody epitope from dengue virus serotype 3 into serotype 4. Scientific Reports. 7: 17169. PMID 29215033 DOI: 10.1038/S41598-017-17355-5  0.752
2017 Maurizio PL, Ferris MT, Keele GR, Miller DR, Shaw GD, Whitmore AC, West A, Morrison CR, Noll KE, Plante KS, Cockrell AS, Threadgill DW, Pardo-Manuel de Villena F, Baric RS, Heise MT, et al. Bayesian Diallel Analysis Reveals Mx1-Dependent and Mx1-Independent Effects on Response to Influenza A Virus in Mice. G3 (Bethesda, Md.). PMID 29187420 DOI: 10.1534/G3.117.300438  0.44
2017 Menachery VD, Gralinski LE, Mitchell HD, Dinnon KH, Leist SR, Yount BL, Graham RL, McAnarney ET, Stratton KG, Cockrell AS, Debbink K, Sims AC, Waters KM, Baric RS. Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis. Msphere. 2. PMID 29152578 DOI: 10.1128/mSphere.00346-17  0.743
2017 Di H, Madden JC, Morantz EK, Tang HY, Graham RL, Baric RS, Brinton MA. Expanded subgenomic mRNA transcriptome and coding capacity of a nidovirus. Proceedings of the National Academy of Sciences of the United States of America. 114: E8895-E8904. PMID 29073030 DOI: 10.1073/Pnas.1706696114  0.326
2017 Lindesmith LC, Kocher JF, Donaldson EF, Debbink K, Mallory ML, Swann EW, Brewer-Jenson PD, Baric RS. Emergence of Novel Human Norovirus GII.17 Strains Correlates with Changes in Blockade Antibody Epitopes. The Journal of Infectious Diseases. PMID 28973354 DOI: 10.1093/Infdis/Jix385  0.809
2017 Gallichotte EN, Dinnon KH, Lim XN, Ng TS, Lim EXY, Menachery VD, Lok SM, Baric RS. CD-loop extension in Zika virus envelope protein key for stability and pathogenesis. The Journal of Infectious Diseases. PMID 28968838 DOI: 10.1093/Infdis/Jix473  0.409
2017 Andrade DV, Katzelnick LC, Widman DG, Balmaseda A, de Silva AM, Baric RS, Harris E. Analysis of Individuals from a Dengue-Endemic Region Helps Define the Footprint and Repertoire of Antibodies Targeting Dengue Virus 3 Type-Specific Epitopes. Mbio. 8. PMID 28928210 DOI: 10.1128/Mbio.01205-17  0.44
2017 Menachery VD, Mitchell HD, Cockrell AS, Gralinski LE, Yount BL, Graham RL, McAnarney ET, Douglas MG, Scobey T, Beall A, Dinnon K, Kocher JF, Hale AE, Stratton KG, Waters KM, ... Baric RS, et al. MERS-CoV Accessory ORFs Play Key Role for Infection and Pathogenesis. Mbio. 8. PMID 28830941 DOI: 10.1128/Mbio.00665-17  0.489
2017 Peck KM, Scobey T, Swanstrom J, Jensen KL, Burch CL, Baric RS, Heise MT. Permissivity of DPP4 Orthologs to MERS-Coronavirus is Governed by Glycosylation and Other Complex Determinants. Journal of Virology. PMID 28747502 DOI: 10.1128/Jvi.00534-17  0.487
2017 Metz SW, Gallichotte EN, Brackbill A, Premkumar L, Miley MJ, Baric R, de Silva AM. In Vitro Assembly and Stabilization of Dengue and Zika Virus Envelope Protein Homo-Dimers. Scientific Reports. 7: 4524. PMID 28674411 DOI: 10.1038/S41598-017-04767-6  0.421
2017 Sheahan TP, Sims AC, Graham RL, Menachery VD, Gralinski LE, Case JB, Leist SR, Pyrc K, Feng JY, Trantcheva I, Bannister R, Park Y, Babusis D, Clarke MO, Mackman RL, ... ... Baric RS, et al. Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses. Science Translational Medicine. 9. PMID 28659436 DOI: 10.1126/Scitranslmed.Aal3653  0.687
2017 Gralinski LE, Menachery VD, Morgan AP, Totura AL, Beall A, Kocher J, Plante J, Harrison-Shostak DC, Schäfer A, Pardo-Manuel de Villena F, Ferris MT, Baric RS. Allelic Variation in the Toll-Like Receptor Adaptor Protein Ticam2 Contributes to SARS-Coronavirus Pathogenesis in Mice. G3 (Bethesda, Md.). 7: 1653-1663. PMID 28592648 DOI: 10.1534/G3.117.041434  0.416
2017 Hou Y, Lin CM, Yokoyama M, Yount BL, Marthaler D, Douglas AL, Ghimire S, Qin Y, Baric RS, Saif LJ, Wang Q. Deletion of a 197-Amino-Acid Region in the N-Terminal Domain of Spike Protein Attenuates Porcine Epidemic Diarrhea Virus in Piglets. Journal of Virology. PMID 28490591 DOI: 10.1128/Jvi.00227-17  0.468
2017 Lindesmith LC, Mallory ML, Jones TA, Richardson C, Goodwin RR, Baehner F, Mendelman PM, Bargatze RF, Baric RS. Impact of Pre-exposure History and Host Genetics on Antibody Avidity Following Norovirus Vaccination. The Journal of Infectious Diseases. 215: 984-991. PMID 28453838 DOI: 10.1093/Infdis/Jix045  0.398
2017 Collins MH, McGowan E, Jadi R, Young E, Lopez CA, Baric RS, Lazear HM, de Silva AM. Lack of Durable Cross-Neutralizing Antibodies Against Zika Virus from Dengue Virus Infection. Emerging Infectious Diseases. 23: 773-781. PMID 28418292 DOI: 10.3201/Eid2305.161630  0.463
2017 Anthony SJ, Gilardi K, Menachery VD, Goldstein T, Ssebide B, Mbabazi R, Navarrete-Macias I, Liang E, Wells H, Hicks A, Petrosov A, Byarugaba DK, Debbink K, Dinnon KH, Scobey T, ... ... Baric RS, et al. Further Evidence for Bats as the Evolutionary Source of Middle East Respiratory Syndrome Coronavirus. Mbio. 8. PMID 28377531 DOI: 10.1128/Mbio.00373-17  0.749
2017 Widman DG, Young E, Yount BL, Plante KS, Gallichotte EN, Carbaugh DL, Peck KM, Plante J, Swanstrom J, Heise MT, Lazear HM, Baric RS. A Reverse Genetics Platform That Spans the Zika Virus Family Tree. Mbio. 8. PMID 28270583 DOI: 10.1128/Mbio.02014-16  0.525
2017 Gallichotte EN, Menachery VD, Yount BL, Widman DG, Dinnon KH, Hartman S, de Silva AM, Baric RS. Epitope Addition and Ablation via Manipulation of a Dengue Virus Serotype 1 Infectious Clone. Msphere. 2. PMID 28251184 DOI: 10.1128/mSphere.00380-16  0.422
2017 Menachery VD, Graham RL, Baric RS. Jumping species-a mechanism for coronavirus persistence and survival. Current Opinion in Virology. 23: 1-7. PMID 28214731 DOI: 10.1016/J.Coviro.2017.01.002  0.33
2017 Schäfer A, Baric RS. Epigenetic Landscape during Coronavirus Infection. Pathogens (Basel, Switzerland). 6. PMID 28212305 DOI: 10.3390/Pathogens6010008  0.443
2017 Burnum-Johnson KE, Kyle JE, Eisfeld AJ, Casey CP, Stratton KG, Gonzalez JF, Habyarimana F, Negretti NM, Sims AC, Chauhan S, Thackray LB, Halfmann PJ, Walters KB, Kim YM, Zink EM, ... ... Baric RS, et al. MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling. The Analyst. PMID 28091625 DOI: 10.1039/C6An02486F  0.382
2017 Jordan R, Hogg A, Warren T, De Wit E, Sheahan T, Lo M, Soloveva V, Weidner J, Gomba L, Feldmann F, Cronin J, Sims A, Cockrell A, Feng J, Trantcheva I, ... ... Baric R, et al. Broad-spectrum Investigational Agent GS-5734 for the Treatment of Ebola, MERS Coronavirus and Other Pathogenic Viral Infections with High Outbreak Potential Open Forum Infectious Diseases. 4: S737-S737. DOI: 10.1093/Ofid/Ofx180.008  0.688
2016 Cockrell AS, Baric RS. An effective DNA vaccine platform for Middle East respiratory syndrome coronavirus. Annals of Translational Medicine. 4: 499. PMID 28149861 DOI: 10.21037/Atm.2016.11.40  0.415
2016 Nivarthi UK, Kose N, Sapparapu G, Widman D, Gallichotte E, Pfaff JM, Doranz BJ, Weiskopf D, Sette A, Durbin AP, Whitehead SS, Baric R, Crowe JE, de Silva AM. Mapping the Human Memory B Cell and Serum Neutralizing Antibody Responses to DENV4 Infection and Vaccination. Journal of Virology. PMID 28031369 DOI: 10.1128/Jvi.02041-16  0.449
2016 Henein S, Swanstrom J, Byers AM, Moser JM, Shaik SF, Bonaparte M, Jackson N, Guy B, Baric R, de Silva AM. Dissecting antibodies induced by a chimeric yellow fever-dengue, live-attenuated, tetravalent dengue vaccine (CYD-TDV) in naïve and dengue exposed individuals. The Journal of Infectious Diseases. PMID 27932620 DOI: 10.1093/Infdis/Jiw576  0.409
2016 Cockrell AS, Yount BL, Scobey T, Jensen K, Douglas M, Beall A, Tang XC, Marasco WA, Heise MT, Baric RS. A mouse model for MERS coronavirus-induced acute respiratory distress syndrome. Nature Microbiology. 2: 16226. PMID 27892925 DOI: 10.1038/Nmicrobiol.2016.226  0.476
2016 Green R, Wilkins C, Thomas S, Sekine A, Ireton RC, Ferris MT, Hendrick DM, Voss K, Pardo-Manuel de Villena F, Baric RS, Heise MT, Gale M. Transcriptional profiles of WNV neurovirulence in a genetically diverse Collaborative Cross population. Genomics Data. 10: 137-140. PMID 27872814 DOI: 10.1016/J.Gdata.2016.10.005  0.396
2016 Green R, Wilkins C, Thomas S, Sekine A, Ireton RC, Ferris MT, Hendrick DM, Voss K, de Villena FP, Baric R, Heise M, Gale M. Identifying protective host gene expression signatures within the spleen during West Nile virus infection in the collaborative cross model. Genomics Data. 10: 114-117. PMID 27843766 DOI: 10.1016/J.Gdata.2016.10.006  0.429
2016 Baric RS, Crosson S, Damania B, Miller SI, Rubin EJ. Next-Generation High-Throughput Functional Annotation of Microbial Genomes. Mbio. 7. PMID 27703071 DOI: 10.1128/Mbio.01245-16  0.327
2016 McDermott JE, Mitchell HD, Gralinski LE, Eisfeld AJ, Josset L, Bankhead A, Neumann G, Tilton SC, Schäfer A, Li C, Fan S, McWeeney S, Baric RS, Katze MG, Waters KM. The effect of inhibition of PP1 and TNFα signaling on pathogenesis of SARS coronavirus. Bmc Systems Biology. 10: 93. PMID 27663205 DOI: 10.1186/S12918-016-0336-6  0.468
2016 Swanstrom JA, Plante JA, Plante KS, Young EF, McGowan E, Gallichotte EN, Widman DG, Heise MT, de Silva AM, Baric RS. Dengue Virus Envelope Dimer Epitope Monoclonal Antibodies Isolated from Dengue Patients Are Protective against Zika Virus. Mbio. 7. PMID 27435464 DOI: 10.1128/Mbio.01123-16  0.491
2016 Zhao J, Zhao J, Mangalam AK, Channappanavar R, Fett C, Meyerholz DK, Agnihothram S, Baric RS, David CS, Perlman S. Airway Memory CD4(+) T Cells Mediate Protective Immunity against Emerging Respiratory Coronaviruses. Immunity. PMID 27287409 DOI: 10.1016/J.Immuni.2016.05.006  0.414
2016 Menachery VD, Yount BL, Debbink K, Agnihothram S, Gralinski LE, Plante JA, Graham RL, Scobey T, Ge XY, Donaldson EF, Randell SH, Lanzavecchia A, Marasco WA, Shi ZL, Baric RS. Corrigendum: A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence. Nature Medicine. 22: 446. PMID 27050591 DOI: 10.1038/Nm0416-446D  0.765
2016 Thornbrough JM, Jha BK, Yount B, Goldstein SA, Li Y, Elliott R, Sims AC, Baric RS, Silverman RH, Weiss SR. Middle East Respiratory Syndrome Coronavirus NS4b Protein Inhibits Host RNase L Activation. Mbio. 7. PMID 27025250 DOI: 10.1128/Mbio.00258-16  0.402
2016 Menachery VD, Yount BL, Sims AC, Debbink K, Agnihothram SS, Gralinski LE, Graham RL, Scobey T, Plante JA, Royal SR, Swanstrom J, Sheahan TP, Pickles RJ, Corti D, Randell SH, ... ... Baric RS, et al. SARS-like WIV1-CoV poised for human emergence. Proceedings of the National Academy of Sciences of the United States of America. PMID 26976607 DOI: 10.1073/Pnas.1517719113  0.822
2016 Messer WB, Yount BL, Royal SR, de Alwis R, Widman DG, Smith SA, Crowe JE, Pfaff JM, Kahle KM, Doranz BJ, Ibarra KD, Harris E, de Silva AM, Baric RS. Functional transplant of a DENV3-specific human monoclonal antibody epitope into DENV1. Journal of Virology. PMID 26962223 DOI: 10.1128/Jvi.00155-16  0.503
2016 Johnson RF, Bagci U, Keith L, Tang X, Mollura DJ, Zeitlin L, Qin J, Huzella L, Bartos CJ, Bohorova N, Bohorov O, Goodman C, Kim DH, Paulty MH, Velasco J, ... ... Baric RS, et al. 3B11-N, a monoclonal antibody against MERS-CoV, reduces lung pathology in rhesus monkeys following intratracheal inoculation of MERS-CoV Jordan-n3/2012. Virology. 490: 49-58. PMID 26828465 DOI: 10.1016/J.Virol.2016.01.004  0.36
2016 Knoll BM, Lindesmith LC, Yount BL, Baric RS, Marty FM. Resolution of diarrhea in an immunocompromised patient with chronic norovirus gastroenteritis correlates with constitution of specific antibody blockade titer. Infection. PMID 26825307 DOI: 10.1007/S15010-016-0875-1  0.352
2016 Beall A, Yount B, Lin CM, Hou Y, Wang Q, Saif L, Baric R. Characterization of a Pathogenic Full-Length cDNA Clone and Transmission Model for Porcine Epidemic Diarrhea Virus Strain PC22A. Mbio. 7. PMID 26733065 DOI: 10.1128/Mbio.01451-15  0.484
2015 Peck KM, Burch CL, Heise MT, Baric RS. Coronavirus Host Range Expansion and Middle East Respiratory Syndrome Coronavirus Emergence: Biochemical Mechanisms and Evolutionary Perspectives. Annual Review of Virology. 2: 95-117. PMID 26958908 DOI: 10.1146/Annurev-Virology-100114-055029  0.329
2015 Menachery VD, Yount BL, Debbink K, Agnihothram S, Gralinski LE, Plante JA, Graham RL, Scobey T, Ge XY, Donaldson EF, Randell SH, Lanzavecchia A, Marasco WA, Shi ZL, Baric RS. A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence. Nature Medicine. PMID 26552008 DOI: 10.1038/Nm.3985  0.835
2015 Gallichotte EN, Widman DG, Yount BL, Wahala WM, Durbin A, Whitehead S, Sariol CA, Crowe JE, de Silva AM, Baric RS. A New Quaternary Structure Epitope on Dengue Virus Serotype 2 Is the Target of Durable Type-Specific Neutralizing Antibodies. Mbio. 6. PMID 26463165 DOI: 10.1128/Mbio.01461-15  0.447
2015 Gralinski LE, Ferris MT, Aylor DL, Whitmore AC, Green R, Frieman MB, Deming D, Menachery VD, Miller DR, Buus RJ, Bell TA, Churchill GA, Threadgill DW, Katze MG, McMillan L, ... ... Baric RS, et al. Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross. Plos Genetics. 11: e1005504. PMID 26452100 DOI: 10.1371/Journal.Pgen.1005504  0.785
2015 Totura AL, Baric RS. Reply to "Statins may decrease the Fatality Rate of MERS Infection". Mbio. 6: e01303-15. PMID 26419878 DOI: 10.1128/Mbio.01303-15  0.351
2015 Corti D, Zhao J, Pedotti M, Simonelli L, Agnihothram S, Fett C, Fernandez-Rodriguez B, Foglierini M, Agatic G, Vanzetta F, Gopal R, Langrish CJ, Barrett NA, Sallusto F, Baric RS, et al. Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus. Proceedings of the National Academy of Sciences of the United States of America. 112: 10473-8. PMID 26216974 DOI: 10.1073/Pnas.1510199112  0.466
2015 Lindesmith LC, Beltramello M, Swanstrom J, Jones TA, Corti D, Lanzavecchia A, Baric RS. Serum Immunoglobulin A Cross-Strain Blockade of Human Noroviruses. Open Forum Infectious Diseases. 2: ofv084. PMID 26180833 DOI: 10.1093/ofid/ofv084  0.362
2015 Menachery VD, Gralinski LE, Baric RS, Ferris MT. New Metrics for Evaluating Viral Respiratory Pathogenesis. Plos One. 10: e0131451. PMID 26115403 DOI: 10.1371/Journal.Pone.0131451  0.46
2015 Totura AL, Whitmore A, Agnihothram S, Schäfer A, Katze MG, Heise MT, Baric RS. Toll-Like Receptor 3 Signaling via TRIF Contributes to a Protective Innate Immune Response to Severe Acute Respiratory Syndrome Coronavirus Infection. Mbio. 6: e00638-15. PMID 26015500 DOI: 10.1128/Mbio.00638-15  0.447
2015 Huang X, Dong W, Milewska A, Golda A, Qi Y, Zhu QK, Marasco WA, Baric RS, Sims AC, Pyrc K, Li W, Sui J. Human Coronavirus HKU1 Spike Protein Uses O-Acetylated Sialic Acid as an Attachment Receptor Determinant and Employs Hemagglutinin-Esterase Protein as a Receptor-Destroying Enzyme. Journal of Virology. 89: 7202-13. PMID 25926653 DOI: 10.1128/Jvi.00854-15  0.33
2015 Lindesmith LC, Ferris MT, Mullan CW, Ferreira J, Debbink K, Swanstrom J, Richardson C, Goodwin RR, Baehner F, Mendelman PM, Bargatze RF, Baric RS. Broad blockade antibody responses in human volunteers after immunization with a multivalent norovirus VLP candidate vaccine: immunological analyses from a phase I clinical trial. Plos Medicine. 12: e1001807. PMID 25803642 DOI: 10.1371/Journal.Pmed.1001807  0.731
2015 Karst SM, Baric RS. What is the reservoir of emergent human norovirus strains? Journal of Virology. 89: 5756-9. PMID 25787285 DOI: 10.1128/JVI.03063-14  0.33
2015 Peck KM, Cockrell AS, Yount BL, Scobey T, Baric RS, Heise MT. Glycosylation of mouse DPP4 plays a role in inhibiting Middle East respiratory syndrome coronavirus infection. Journal of Virology. 89: 4696-9. PMID 25653445 DOI: 10.1128/Jvi.03445-14  0.378
2015 Zhang R, Li Y, Cowley TJ, Steinbrenner AD, Phillips JM, Yount BL, Baric RS, Weiss SR. The nsp1, nsp13, and M proteins contribute to the hepatotropism of murine coronavirus JHM.WU. Journal of Virology. 89: 3598-609. PMID 25589656 DOI: 10.1128/Jvi.03535-14  0.332
2015 Vatter HA, Donaldson EF, Huynh J, Rawlings S, Manoharan M, Legasse A, Planer S, Dickerson MF, Lewis AD, Colgin LM, Axthelm MK, Pecotte JK, Baric RS, Wong SW, Brinton MA. A simian hemorrhagic fever virus isolate from persistently infected baboons efficiently induces hemorrhagic fever disease in Japanese macaques. Virology. 474: 186-98. PMID 25463617 DOI: 10.1016/J.Virol.2014.10.018  0.695
2015 Gralinski LE, Baric RS. Molecular pathology of emerging coronavirus infections. The Journal of Pathology. 235: 185-95. PMID 25270030 DOI: 10.1002/path.4454  0.335
2015 Widman DG, Baric RS. Dengue virus envelope protein domain I/II hinge: a key target for dengue virus vaccine design? Expert Review of Vaccines. 14: 5-8. PMID 25249440 DOI: 10.1586/14760584.2015.961431  0.436
2015 Messer WB, De Alwis R, Yount BL, Royal SR, Huynh JP, Smith SA, Crowe JE, Doranz BJ, Kahle KM, Pfaff JM, White LJ, Sariol CA, De Silva AM, Baric RS. Retraction: Dengue virus envelope protein domain I/II hinge determines long-lived serotype-specific dengue immunity (Proc Natl Acad Sci USA (2014) 111, (1939-1944) DOI: 10.1073/pnas.1317350111) Proceedings of the National Academy of Sciences of the United States of America. 112: E2738. DOI: 10.1073/Pnas.1506982112  0.383
2014 Vatter HA, Di H, Donaldson EF, Baric RS, Brinton MA. Corrigendum to "Each of the eight simian hemorrhagic fever virus minor structural proteins is functionally important" [Virology 462-463 (2014) 351-362]. Virology. 464: 461. PMID 29054158 DOI: 10.1016/J.Virol.2014.07.045  0.631
2014 Aevermann BD, Pickett BE, Kumar S, Klem EB, Agnihothram S, Askovich PS, Bankhead A, Bolles M, Carter V, Chang J, Clauss TR, Dash P, Diercks AH, Eisfeld AJ, Ellis A, ... ... Baric R, et al. A comprehensive collection of systems biology data characterizing the host response to viral infection. Scientific Data. 1: 140033. PMID 25977790 DOI: 10.1038/Sdata.2014.33  0.353
2014 Selinger C, Tisoncik-Go J, Menachery VD, Agnihothram S, Law GL, Chang J, Kelly SM, Sova P, Baric RS, Katze MG. Cytokine systems approach demonstrates differences in innate and pro-inflammatory host responses between genetically distinct MERS-CoV isolates. Bmc Genomics. 15: 1161. PMID 25534508 DOI: 10.1186/1471-2164-15-1161  0.351
2014 Menachery VD, Debbink K, Baric RS. Coronavirus non-structural protein 16: evasion, attenuation, and possible treatments. Virus Research. 194: 191-9. PMID 25278144 DOI: 10.1016/J.Virusres.2014.09.009  0.722
2014 Vega E, Donaldson E, Huynh J, Barclay L, Lopman B, Baric R, Chen LF, Vinjé J. RNA populations in immunocompromised patients as reservoirs for novel norovirus variants. Journal of Virology. 88: 14184-96. PMID 25275120 DOI: 10.1128/Jvi.02494-14  0.648
2014 Sui J, Deming M, Rockx B, Liddington RC, Zhu QK, Baric RS, Marasco WA. Effects of human anti-spike protein receptor binding domain antibodies on severe acute respiratory syndrome coronavirus neutralization escape and fitness. Journal of Virology. 88: 13769-80. PMID 25231316 DOI: 10.1128/Jvi.02232-14  0.49
2014 Yang Y, Du L, Liu C, Wang L, Ma C, Tang J, Baric RS, Jiang S, Li F. Receptor usage and cell entry of bat coronavirus HKU4 provide insight into bat-to-human transmission of MERS coronavirus. Proceedings of the National Academy of Sciences of the United States of America. 111: 12516-21. PMID 25114257 DOI: 10.1073/Pnas.1405889111  0.391
2014 Deng X, Agnihothram S, Mielech AM, Nichols DB, Wilson MW, StJohn SE, Larsen SD, Mesecar AD, Lenschow DJ, Baric RS, Baker SC. A chimeric virus-mouse model system for evaluating the function and inhibition of papain-like proteases of emerging coronaviruses. Journal of Virology. 88: 11825-33. PMID 25100850 DOI: 10.1128/Jvi.01749-14  0.465
2014 Vatter HA, Di H, Donaldson EF, Baric RS, Brinton MA. Each of the eight simian hemorrhagic fever virus minor structural proteins is functionally important. Virology. 462: 351-62. PMID 25036340 DOI: 10.1016/J.Virol.2014.06.001  0.665
2014 Josset L, Tchitchek N, Gralinski LE, Ferris MT, Eisfeld AJ, Green RR, Thomas MJ, Tisoncik-Go J, Schroth GP, Kawaoka Y, Manuel de Villena FP, Baric RS, Heise MT, Peng X, Katze MG. Annotation of long non-coding RNAs expressed in collaborative cross founder mice in response to respiratory virus infection reveals a new class of interferon-stimulated transcripts. Rna Biology. 11: 875-90. PMID 24922324 DOI: 10.4161/Rna.29442  0.425
2014 Xiong H, Morrison J, Ferris MT, Gralinski LE, Whitmore AC, Green R, Thomas MJ, Tisoncik-Go J, Schroth GP, Pardo-Manuel de Villena F, Baric RS, Heise MT, Peng X, Katze MG. Genomic profiling of collaborative cross founder mice infected with respiratory viruses reveals novel transcripts and infection-related strain-specific gene and isoform expression. G3 (Bethesda, Md.). 4: 1429-44. PMID 24902603 DOI: 10.1534/G3.114.011759  0.447
2014 Lindesmith LC, Donaldson EF, Beltramello M, Pintus S, Corti D, Swanstrom J, Debbink K, Jones TA, Lanzavecchia A, Baric RS. Particle conformation regulates antibody access to a conserved GII.4 norovirus blockade epitope. Journal of Virology. 88: 8826-42. PMID 24872579 DOI: 10.1128/Jvi.01192-14  0.798
2014 Menachery VD, Eisfeld AJ, Schäfer A, Josset L, Sims AC, Proll S, Fan S, Li C, Neumann G, Tilton SC, Chang J, Gralinski LE, Long C, Green R, Williams CM, ... ... Baric RS, et al. Pathogenic influenza viruses and coronaviruses utilize similar and contrasting approaches to control interferon-stimulated gene responses. Mbio. 5: e01174-14. PMID 24846384 DOI: 10.1128/Mbio.01174-14  0.36
2014 Schäfer A, Baric RS, Ferris MT. Systems approaches to Coronavirus pathogenesis. Current Opinion in Virology. 6: 61-9. PMID 24842079 DOI: 10.1016/J.Coviro.2014.04.007  0.447
2014 Tang XC, Agnihothram SS, Jiao Y, Stanhope J, Graham RL, Peterson EC, Avnir Y, Tallarico AS, Sheehan J, Zhu Q, Baric RS, Marasco WA. Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution. Proceedings of the National Academy of Sciences of the United States of America. 111: E2018-26. PMID 24778221 DOI: 10.1073/Pnas.1402074111  0.368
2014 Debbink K, Lindesmith LC, Donaldson EF, Swanstrom J, Baric RS. Chimeric GII.4 norovirus virus-like-particle-based vaccines induce broadly blocking immune responses. Journal of Virology. 88: 7256-66. PMID 24741081 DOI: 10.1128/Jvi.00785-14  0.81
2014 Agnihothram S, Yount BL, Donaldson EF, Huynh J, Menachery VD, Gralinski LE, Graham RL, Becker MM, Tomar S, Scobey TD, Osswald HL, Whitmore A, Gopal R, Ghosh AK, Mesecar A, ... ... Baric RS, et al. A mouse model for Betacoronavirus subgroup 2c using a bat coronavirus strain HKU5 variant. Mbio. 5: e00047-14. PMID 24667706 DOI: 10.1128/Mbio.00047-14  0.713
2014 Debbink K, Lindesmith LC, Ferris MT, Swanstrom J, Beltramello M, Corti D, Lanzavecchia A, Baric RS. Within-host evolution results in antigenically distinct GII.4 noroviruses. Journal of Virology. 88: 7244-55. PMID 24648459 DOI: 10.1128/Jvi.00203-14  0.732
2014 Zhao J, Li K, Wohlford-Lenane C, Agnihothram SS, Fett C, Zhao J, Gale MJ, Baric RS, Enjuanes L, Gallagher T, McCray PB, Perlman S. Rapid generation of a mouse model for Middle East respiratory syndrome. Proceedings of the National Academy of Sciences of the United States of America. 111: 4970-5. PMID 24599590 DOI: 10.1073/Pnas.1323279111  0.435
2014 Debbink K, Lindesmith LC, Baric RS. The state of norovirus vaccines. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 58: 1746-52. PMID 24585561 DOI: 10.1093/Cid/Ciu120  0.694
2014 Cockrell AS, Peck KM, Yount BL, Agnihothram SS, Scobey T, Curnes NR, Baric RS, Heise MT. Mouse dipeptidyl peptidase 4 is not a functional receptor for Middle East respiratory syndrome coronavirus infection. Journal of Virology. 88: 5195-9. PMID 24574399 DOI: 10.1128/Jvi.03764-13  0.398
2014 Menachery VD, Yount BL, Josset L, Gralinski LE, Scobey T, Agnihothram S, Katze MG, Baric RS. Attenuation and restoration of severe acute respiratory syndrome coronavirus mutant lacking 2'-o-methyltransferase activity. Journal of Virology. 88: 4251-64. PMID 24478444 DOI: 10.1128/Jvi.03571-13  0.447
2014 Messer WB, de Alwis R, Yount BL, Royal SR, Huynh JP, Smith SA, Crowe JE, Doranz BJ, Kahle KM, Pfaff JM, White LJ, Sariol CA, de Silva AM, Baric RS. Dengue virus envelope protein domain I/II hinge determines long-lived serotype-specific dengue immunity. Proceedings of the National Academy of Sciences of the United States of America. 111: 1939-44. PMID 24385585 DOI: 10.1073/Pnas.1317350111  0.496
2014 Agnihothram S, Gopal R, Yount BL, Donaldson EF, Menachery VD, Graham RL, Scobey TD, Gralinski LE, Denison MR, Zambon M, Baric RS. Evaluation of serologic and antigenic relationships between middle eastern respiratory syndrome coronavirus and other coronaviruses to develop vaccine platforms for the rapid response to emerging coronaviruses. The Journal of Infectious Diseases. 209: 995-1006. PMID 24253287 DOI: 10.1093/Infdis/Jit609  0.716
2014 Swanstrom J, Lindesmith LC, Donaldson EF, Yount B, Baric RS. Characterization of blockade antibody responses in GII.2.1976 Snow Mountain virus-infected subjects. Journal of Virology. 88: 829-37. PMID 24173225 DOI: 10.1128/Jvi.02793-13  0.717
2014 Messer WB, De Alwis R, Yount BL, Royal SR, Huynh JP, Smith SA, Crowe JE, Doranz BJ, Kahle KM, Pfaff JM, White LJ, Sariol CA, De Silva AM, Baric RS. Dengue virus envelope protein domain I/II hinge determines long-lived serotype-specific dengue immunity (Proceedings of the National Academy of Sciences of the United States of America (2014) 111, 5, (1939-1944) doi:10.1073/pnas.1317350111) Proceedings of the National Academy of Sciences of the United States of America. 111: 6115. DOI: 10.1073/Pnas.1405351111  0.358
2014 Vatter HA, Di H, Donaldson EF, Baric RS, Brinton MA. Corrigendum to "Each of the eight simian hemorrhagic fever virus minor structural proteins is functionally important" [Virology 462-463 (2014) 351-362] Virology. DOI: 10.1016/j.virol.2014.07.045  0.626
2013 Debbink K, Costantini V, Swanstrom J, Agnihothram S, Vinjé J, Baric R, Lindesmith L. Human norovirus detection and production, quantification, and storage of virus-like particles. Current Protocols in Microbiology. 31: 15K.1.1-15K.1.45. PMID 24510290 DOI: 10.1002/9780471729259.Mc15K01S31  0.744
2013 Graham RL, Donaldson EF, Baric RS. A decade after SARS: strategies for controlling emerging coronaviruses. Nature Reviews. Microbiology. 11: 836-48. PMID 24217413 DOI: 10.1038/Nrmicro3143  0.663
2013 Scobey T, Yount BL, Sims AC, Donaldson EF, Agnihothram SS, Menachery VD, Graham RL, Swanstrom J, Bove PF, Kim JD, Grego S, Randell SH, Baric RS. Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus. Proceedings of the National Academy of Sciences of the United States of America. 110: 16157-62. PMID 24043791 DOI: 10.1073/Pnas.1311542110  0.677
2013 Mitchell HD, Eisfeld AJ, Sims AC, McDermott JE, Matzke MM, Webb-Robertson BJ, Tilton SC, Tchitchek N, Josset L, Li C, Ellis AL, Chang JH, Heegel RA, Luna ML, Schepmoes AA, ... ... Baric RS, et al. A network integration approach to predict conserved regulators related to pathogenicity of influenza and SARS-CoV respiratory viruses. Plos One. 8: e69374. PMID 23935999 DOI: 10.1371/Journal.Pone.0069374  0.462
2013 Gralinski LE, Bankhead A, Jeng S, Menachery VD, Proll S, Belisle SE, Matzke M, Webb-Robertson BJ, Luna ML, Shukla AK, Ferris MT, Bolles M, Chang J, Aicher L, Waters KM, ... ... Baric RS, et al. Mechanisms of severe acute respiratory syndrome coronavirus-induced acute lung injury. Mbio. 4. PMID 23919993 DOI: 10.1128/Mbio.00271-13  0.814
2013 Debbink K, Lindesmith LC, Donaldson EF, Costantini V, Beltramello M, Corti D, Swanstrom J, Lanzavecchia A, Vinjé J, Baric RS. Emergence of new pandemic GII.4 Sydney norovirus strain correlates with escape from herd immunity. The Journal of Infectious Diseases. 208: 1877-87. PMID 23908476 DOI: 10.1093/Infdis/Jit370  0.812
2013 Chen Y, Rajashankar KR, Yang Y, Agnihothram SS, Liu C, Lin YL, Baric RS, Li F. Crystal structure of the receptor-binding domain from newly emerged Middle East respiratory syndrome coronavirus. Journal of Virology. 87: 10777-83. PMID 23903833 DOI: 10.1128/Jvi.01756-13  0.423
2013 Tchitchek N, Eisfeld AJ, Tisoncik-Go J, Josset L, Gralinski LE, Bécavin C, Tilton SC, Webb-Robertson BJ, Ferris MT, Totura AL, Li C, Neumann G, Metz TO, Smith RD, Waters KM, ... Baric R, et al. Specific mutations in H5N1 mainly impact the magnitude and velocity of the host response in mice. Bmc Systems Biology. 7: 69. PMID 23895213 DOI: 10.1186/1752-0509-7-69  0.451
2013 de Groot RJ, Baker SC, Baric RS, Brown CS, Drosten C, Enjuanes L, Fouchier RA, Galiano M, Gorbalenya AE, Memish ZA, Perlman S, Poon LL, Snijder EJ, Stephens GM, Woo PC, et al. Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group. Journal of Virology. 87: 7790-2. PMID 23678167 DOI: 10.1128/Jvi.01244-13  0.305
2013 Josset L, Menachery VD, Gralinski LE, Agnihothram S, Sova P, Carter VS, Yount BL, Graham RL, Baric RS, Katze MG. Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus. Mbio. 4: e00165-13. PMID 23631916 DOI: 10.1128/Mbio.00165-13  0.348
2013 Chan RW, Chan MC, Agnihothram S, Chan LL, Kuok DI, Fong JH, Guan Y, Poon LL, Baric RS, Nicholls JM, Peiris JS. Tropism of and innate immune responses to the novel human betacoronavirus lineage C virus in human ex vivo respiratory organ cultures. Journal of Virology. 87: 6604-14. PMID 23552422 DOI: 10.1128/Jvi.00009-13  0.315
2013 Ferris MT, Aylor DL, Bottomly D, Whitmore AC, Aicher LD, Bell TA, Bradel-Tretheway B, Bryan JT, Buus RJ, Gralinski LE, Haagmans BL, McMillan L, Miller DR, Rosenzweig E, Valdar W, ... ... Baric RS, et al. Modeling host genetic regulation of influenza pathogenesis in the collaborative cross. Plos Pathogens. 9: e1003196. PMID 23468633 DOI: 10.1371/Journal.Ppat.1003196  0.438
2013 Zhou Y, Austin SK, Fremont DH, Yount BL, Huynh JP, de Silva AM, Baric RS, Messer WB. The mechanism of differential neutralization of dengue serotype 3 strains by monoclonal antibody 8A1 Virology. 439: 57-64. PMID 23453578 DOI: 10.1016/J.Virol.2013.01.022  0.386
2013 Sims AC, Tilton SC, Menachery VD, Gralinski LE, Schäfer A, Matzke MM, Webb-Robertson BJ, Chang J, Luna ML, Long CE, Shukla AK, Bankhead AR, Burkett SE, Zornetzer G, Tseng CT, ... ... Baric RS, et al. Release of severe acute respiratory syndrome coronavirus nuclear import block enhances host transcription in human lung cells. Journal of Virology. 87: 3885-902. PMID 23365422 DOI: 10.1128/Jvi.02520-12  0.36
2013 Plant EP, Sims AC, Baric RS, Dinman JD, Taylor DR. Altering SARS coronavirus frameshift efficiency affects genomic and subgenomic RNA production. Viruses. 5: 279-94. PMID 23334702 DOI: 10.3390/V5010279  0.59
2013 Ishimaru D, Plant EP, Sims AC, Yount BL, Roth BM, Eldho NV, Pérez-Alvarado GC, Armbruster DW, Baric RS, Dinman JD, Taylor DR, Hennig M. RNA dimerization plays a role in ribosomal frameshifting of the SARS coronavirus. Nucleic Acids Research. 41: 2594-608. PMID 23275571 DOI: 10.1093/Nar/Gks1361  0.544
2013 Lindesmith LC, Costantini V, Swanstrom J, Debbink K, Donaldson EF, Vinjé J, Baric RS. Emergence of a norovirus GII.4 strain correlates with changes in evolving blockade epitopes. Journal of Virology. 87: 2803-13. PMID 23269783 DOI: 10.1128/Jvi.03106-12  0.798
2012 Graham RL, Becker MM, Eckerle LD, Bolles M, Denison MR, Baric RS. A live, impaired-fidelity coronavirus vaccine protects in an aged, immunocompromised mouse model of lethal disease. Nature Medicine. 18: 1820-6. PMID 23142821 DOI: 10.1038/Nm.2972  0.822
2012 Debbink K, Lindesmith LC, Donaldson EF, Baric RS. Norovirus immunity and the great escape. Plos Pathogens. 8: e1002921. PMID 23093932 DOI: 10.1371/Journal.Ppat.1002921  0.823
2012 Anderson LJ, Baric RS. Emerging human coronaviruses--disease potential and preparedness. The New England Journal of Medicine. 367: 1850-2. PMID 23075144 DOI: 10.1056/Nejme1212300  0.387
2012 Huynh J, Li S, Yount B, Smith A, Sturges L, Olsen JC, Nagel J, Johnson JB, Agnihothram S, Gates JE, Frieman MB, Baric RS, Donaldson EF. Evidence supporting a zoonotic origin of human coronavirus strain NL63. Journal of Virology. 86: 12816-25. PMID 22993147 DOI: 10.1128/Jvi.00906-12  0.772
2012 Rani M, Bolles M, Donaldson EF, Van Blarcom T, Baric R, Iverson B, Georgiou G. Increased antibody affinity confers broad in vitro protection against escape mutants of severe acute respiratory syndrome coronavirus. Journal of Virology. 86: 9113-21. PMID 22696652 DOI: 10.1128/Jvi.00233-12  0.804
2012 Lindesmith LC, Beltramello M, Donaldson EF, Corti D, Swanstrom J, Debbink K, Lanzavecchia A, Baric RS. Immunogenetic mechanisms driving norovirus GII.4 antigenic variation. Plos Pathogens. 8: e1002705. PMID 22615565 DOI: 10.1371/Journal.Ppat.1002705  0.819
2012 de Alwis R, Smith SA, Olivarez NP, Messer WB, Huynh JP, Wahala WM, White LJ, Diamond MS, Baric RS, Crowe JE, de Silva AM. Identification of human neutralizing antibodies that bind to complex epitopes on dengue virions. Proceedings of the National Academy of Sciences of the United States of America. 109: 7439-44. PMID 22499787 DOI: 10.1073/Pnas.1200566109  0.438
2012 Messer WB, Yount B, Hacker KE, Donaldson EF, Huynh JP, de Silva AM, Baric RS. Development and characterization of a reverse genetic system for studying dengue virus serotype 3 strain variation and neutralization Plos Neglected Tropical Diseases. 6. PMID 22389731 DOI: 10.1371/Journal.Pntd.0001486  0.713
2012 Bottomly D, Ferris MT, Aicher LD, Rosenzweig E, Whitmore A, Aylor DL, Haagmans BL, Gralinski LE, Bradel-Tretheway BG, Bryan JT, Threadgill DW, de Villena FP, Baric RS, Katze MG, Heise M, et al. Expression quantitative trait Loci for extreme host response to influenza a in pre-collaborative cross mice. G3 (Bethesda, Md.). 2: 213-21. PMID 22384400 DOI: 10.1534/G3.111.001800  0.434
2012 Varshney B, Agnihothram S, Agnihotram S, Tan YJ, Baric R, Lal SK. SARS coronavirus 3b accessory protein modulates transcriptional activity of RUNX1b. Plos One. 7: e29542. PMID 22253733 DOI: 10.1371/Journal.Pone.0029542  0.333
2012 Bolles M, Donaldson E, Baric R. SARS-CoV and emergent coronaviruses: viral determinants of interspecies transmission. Current Opinion in Virology. 1: 624-34. PMID 22180768 DOI: 10.1016/J.Coviro.2011.10.012  0.823
2012 Debbink K, Donaldson EF, Lindesmith LC, Baric RS. Genetic mapping of a highly variable norovirus GII.4 blockade epitope: potential role in escape from human herd immunity. Journal of Virology. 86: 1214-26. PMID 22090110 DOI: 10.1128/Jvi.06189-11  0.804
2012 Lindesmith LC, Debbink K, Swanstrom J, Vinjé J, Costantini V, Baric RS, Donaldson EF. Monoclonal antibody-based antigenic mapping of norovirus GII.4-2002. Journal of Virology. 86: 873-83. PMID 22090098 DOI: 10.1128/Jvi.06200-11  0.815
2012 Frieman M, Yount B, Agnihothram S, Page C, Donaldson E, Roberts A, Vogel L, Woodruff B, Scorpio D, Subbarao K, Baric RS. Molecular determinants of severe acute respiratory syndrome coronavirus pathogenesis and virulence in young and aged mouse models of human disease. Journal of Virology. 86: 884-97. PMID 22072787 DOI: 10.1128/Jvi.05957-11  0.824
2012 Menachery V, Sims A, Eisfeld A, Gralinski L, Chang J, Waters K, Metz T, Kawaoka Y, Katze M, Baric R. P115 Pathogenic Influenza A viruses and SARS-Coronaviruses modulate global interferon stimulated gene induction through diverse mechanisms Cytokine. 59: 556. DOI: 10.1016/J.Cyto.2012.06.206  0.479
2011 Frieman M, Basu D, Matthews K, Taylor J, Jones G, Pickles R, Baric R, Engel DA. Yeast based small molecule screen for inhibitors of SARS-CoV. Plos One. 6: e28479. PMID 22164298 DOI: 10.1371/Journal.Pone.0028479  0.711
2011 Peng X, Gralinski L, Ferris MT, Frieman MB, Thomas MJ, Proll S, Korth MJ, Tisoncik JR, Heise M, Luo S, Schroth GP, Tumpey TM, Li C, Kawaoka Y, Baric RS, et al. Integrative deep sequencing of the mouse lung transcriptome reveals differential expression of diverse classes of small RNAs in response to respiratory virus infection. Mbio. 2. PMID 22086488 DOI: 10.1128/Mbio.00198-11  0.644
2011 Bolles M, Deming D, Long K, Agnihothram S, Whitmore A, Ferris M, Funkhouser W, Gralinski L, Totura A, Heise M, Baric RS. A double-inactivated severe acute respiratory syndrome coronavirus vaccine provides incomplete protection in mice and induces increased eosinophilic proinflammatory pulmonary response upon challenge. Journal of Virology. 85: 12201-15. PMID 21937658 DOI: 10.1128/Jvi.06048-11  0.82
2011 Seitz SR, Leon JS, Schwab KJ, Lyon GM, Dowd M, McDaniels M, Abdulhafid G, Fernandez ML, Lindesmith LC, Baric RS, Moe CL. Norovirus infectivity in humans and persistence in water. Applied and Environmental Microbiology. 77: 6884-8. PMID 21856841 DOI: 10.1128/Aem.05806-11  0.39
2011 Takanashi S, Wang Q, Chen N, Shen Q, Jung K, Zhang Z, Yokoyama M, Lindesmith LC, Baric RS, Saif LJ. Characterization of emerging GII.g/GII.12 noroviruses from a gastroenteritis outbreak in the United States in 2010. Journal of Clinical Microbiology. 49: 3234-44. PMID 21752978 DOI: 10.1128/Jcm.00305-11  0.409
2011 de Alwis R, Beltramello M, Messer WB, Sukupolvi-Petty S, Wahala WM, Kraus A, Olivarez NP, Pham Q, Brien JD, Brian J, Tsai WY, Wang WK, Halstead S, Kliks S, Diamond MS, ... Baric R, et al. In-depth analysis of the antibody response of individuals exposed to primary dengue virus infection. Plos Neglected Tropical Diseases. 5: e1188. PMID 21713020 DOI: 10.1371/Journal.Pntd.0001188  0.442
2011 Denison MR, Graham RL, Donaldson EF, Eckerle LD, Baric RS. Coronaviruses: an RNA proofreading machine regulates replication fidelity and diversity. Rna Biology. 8: 270-9. PMID 21593585 DOI: 10.4161/Rna.8.2.15013  0.627
2011 Rockx B, Feldmann F, Brining D, Gardner D, LaCasse R, Kercher L, Long D, Rosenke R, Virtaneva K, Sturdevant DE, Porcella SF, Mattoon J, Parnell M, Baric RS, Feldmann H. Comparative pathogenesis of three human and zoonotic SARS-CoV strains in cynomolgus macaques. Plos One. 6: e18558. PMID 21533129 DOI: 10.1371/Journal.Pone.0018558  0.472
2011 Aylor DL, Valdar W, Foulds-Mathes W, Buus RJ, Verdugo RA, Baric RS, Ferris MT, Frelinger JA, Heise M, Frieman MB, Gralinski LE, Bell TA, Didion JD, Hua K, Nehrenberg DL, et al. Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Research. 21: 1213-22. PMID 21406540 DOI: 10.1101/Gr.111310.110  0.561
2011 Lindesmith LC, Donaldson EF, Baric RS. Norovirus GII.4 strain antigenic variation. Journal of Virology. 85: 231-42. PMID 20980508 DOI: 10.1128/Jvi.01364-10  0.703
2011 Sheahan T, Whitmore A, Long K, Ferris M, Rockx B, Funkhouser W, Donaldson E, Gralinski L, Collier M, Heise M, Davis N, Johnston R, Baric RS. Successful vaccination strategies that protect aged mice from lethal challenge from influenza virus and heterologous severe acute respiratory syndrome coronavirus. Journal of Virology. 85: 217-30. PMID 20980507 DOI: 10.1128/Jvi.01805-10  0.776
2010 te Velthuis AJ, van den Worm SH, Sims AC, Baric RS, Snijder EJ, van Hemert MJ. Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture. Plos Pathogens. 6: e1001176. PMID 21079686 DOI: 10.1371/Journal.Ppat.1001176  0.364
2010 Tian P, Yang D, Jiang X, Zhong W, Cannon JL, Burkhardt W, Woods JW, Hartman G, Lindesmith L, Baric RS, Mandrell R. Specificity and kinetics of norovirus binding to magnetic bead-conjugated histo-blood group antigens. Journal of Applied Microbiology. 109: 1753-62. PMID 21040268 DOI: 10.1111/J.1365-2672.2010.04812.X  0.301
2010 Peng X, Gralinski L, Armour CD, Ferris MT, Thomas MJ, Proll S, Bradel-Tretheway BG, Korth MJ, Castle JC, Biery MC, Bouzek HK, Haynor DR, Frieman MB, Heise M, Raymond CK, ... Baric RS, et al. Unique signatures of long noncoding RNA expression in response to virus infection and altered innate immune signaling. Mbio. 1. PMID 20978541 DOI: 10.1128/Mbio.00206-10  0.672
2010 Pyrc K, Sims AC, Dijkman R, Jebbink M, Long C, Deming D, Donaldson E, Vabret A, Baric R, van der Hoek L, Pickles R. Culturing the unculturable: human coronavirus HKU1 infects, replicates, and produces progeny virions in human ciliated airway epithelial cell cultures. Journal of Virology. 84: 11255-63. PMID 20719951 DOI: 10.1128/Jvi.00947-10  0.817
2010 Zornetzer GA, Frieman MB, Rosenzweig E, Korth MJ, Page C, Baric RS, Katze MG. Transcriptomic analysis reveals a mechanism for a prefibrotic phenotype in STAT1 knockout mice during severe acute respiratory syndrome coronavirus infection. Journal of Virology. 84: 11297-309. PMID 20702617 DOI: 10.1128/Jvi.01130-10  0.81
2010 LoBue AD, Lindesmith LC, Baric RS. Identification of cross-reactive norovirus CD4+ T cell epitopes. Journal of Virology. 84: 8530-8. PMID 20573810 DOI: 10.1128/Jvi.00727-10  0.826
2010 Frieman MB, Chen J, Morrison TE, Whitmore A, Funkhouser W, Ward JM, Lamirande EW, Roberts A, Heise M, Subbarao K, Baric RS. SARS-CoV pathogenesis is regulated by a STAT1 dependent but a type I, II and III interferon receptor independent mechanism. Plos Pathogens. 6: e1000849. PMID 20386712 DOI: 10.1371/Journal.Ppat.1000849  0.652
2010 Wahala WM, Donaldson EF, de Alwis R, Accavitti-Loper MA, Baric RS, de Silva AM. Natural strain variation and antibody neutralization of dengue serotype 3 viruses. Plos Pathogens. 6: e1000821. PMID 20333252 DOI: 10.1371/Journal.Ppat.1000821  0.67
2010 Rockx B, Donaldson E, Frieman M, Sheahan T, Corti D, Lanzavecchia A, Baric RS. Escape from human monoclonal antibody neutralization affects in vitro and in vivo fitness of severe acute respiratory syndrome coronavirus. The Journal of Infectious Diseases. 201: 946-55. PMID 20144042 DOI: 10.1086/651022  0.814
2010 Donaldson EF, Lindesmith LC, Lobue AD, Baric RS. Viral shape-shifting: norovirus evasion of the human immune system. Nature Reviews. Microbiology. 8: 231-41. PMID 20125087 DOI: 10.1038/Nrmicro2296  0.824
2010 Lindesmith LC, Donaldson E, Leon J, Moe CL, Frelinger JA, Johnston RE, Weber DJ, Baric RS. Heterotypic humoral and cellular immune responses following Norwalk virus infection. Journal of Virology. 84: 1800-15. PMID 20007270 DOI: 10.1128/Jvi.02179-09  0.663
2010 Graham RL, Baric RS. Recombination, reservoirs, and the modular spike: mechanisms of coronavirus cross-species transmission. Journal of Virology. 84: 3134-46. PMID 19906932 DOI: 10.1128/Jvi.01394-09  0.33
2010 Freundt EC, Yu L, Goldsmith CS, Welsh S, Cheng A, Yount B, Liu W, Frieman MB, Buchholz UJ, Screaton GR, Lippincott-Schwartz J, Zaki SR, Xu XN, Baric RS, Subbarao K, et al. The open reading frame 3a protein of severe acute respiratory syndrome-associated coronavirus promotes membrane rearrangement and cell death. Journal of Virology. 84: 1097-109. PMID 19889773 DOI: 10.1128/Jvi.01662-09  0.608
2010 Ortiz-Alcantara J, Bhardwaj K, Palaninathan S, Frieman M, Baric RS, Kao CC. Small molecule inhibitors of the SARS-CoV Nsp15 endoribonuclease Virus Adaptation and Treatment. 2: 125-133. DOI: 10.2147/Vaat.S12733  0.589
2010 Sheahan TP, Baric RS. SARS coronavirus pathogenesis and therapeutic treatment design Molecular Biology of the Sars-Coronavirus. 195-230. DOI: 10.1007/978-3-642-03683-5_13  0.701
2009 Day CW, Baric R, Cai SX, Frieman M, Kumaki Y, Morrey JD, Smee DF, Barnard DL. A new mouse-adapted strain of SARS-CoV as a lethal model for evaluating antiviral agents in vitro and in vivo. Virology. 395: 210-22. PMID 19853271 DOI: 10.1016/J.Virol.2009.09.023  0.63
2009 Rockx B, Baas T, Zornetzer GA, Haagmans B, Sheahan T, Frieman M, Dyer MD, Teal TH, Proll S, van den Brand J, Baric R, Katze MG. Early upregulation of acute respiratory distress syndrome-associated cytokines promotes lethal disease in an aged-mouse model of severe acute respiratory syndrome coronavirus infection. Journal of Virology. 83: 7062-74. PMID 19420084 DOI: 10.1128/Jvi.00127-09  0.773
2009 Frieman M, Ratia K, Johnston RE, Mesecar AD, Baric RS. Severe acute respiratory syndrome coronavirus papain-like protease ubiquitin-like domain and catalytic domain regulate antagonism of IRF3 and NF-kappaB signaling. Journal of Virology. 83: 6689-705. PMID 19369340 DOI: 10.1128/Jvi.02220-08  0.619
2009 Liao HI, Olson CA, Hwang S, Deng H, Wong E, Baric RS, Roberts RW, Sun R. mRNA display design of fibronectin-based intrabodies that detect and inhibit severe acute respiratory syndrome coronavirus nucleocapsid protein. The Journal of Biological Chemistry. 284: 17512-20. PMID 19364769 DOI: 10.1074/Jbc.M901547200  0.403
2009 Cannon JL, Lindesmith LC, Donaldson EF, Saxe L, Baric RS, Vinjé J. Herd immunity to GII.4 noroviruses is supported by outbreak patient sera. Journal of Virology. 83: 5363-74. PMID 19297483 DOI: 10.1128/Jvi.02518-08  0.697
2009 LoBue AD, Thompson JM, Lindesmith L, Johnston RE, Baric RS. Alphavirus-adjuvanted norovirus-like particle vaccines: heterologous, humoral, and mucosal immune responses protect against murine norovirus challenge. Journal of Virology. 83: 3212-27. PMID 19176631 DOI: 10.1128/Jvi.01650-08  0.82
2009 Miknis ZJ, Donaldson EF, Umland TC, Rimmer RA, Baric RS, Schultz LW. Severe acute respiratory syndrome coronavirus nsp9 dimerization is essential for efficient viral growth. Journal of Virology. 83: 3007-18. PMID 19153232 DOI: 10.1128/Jvi.01505-08  0.677
2009 Basu D, Walkiewicz MP, Frieman M, Baric RS, Auble DT, Engel DA. Novel influenza virus NS1 antagonists block replication and restore innate immune function. Journal of Virology. 83: 1881-91. PMID 19052087 DOI: 10.1128/Jvi.01805-08  0.662
2009 Rockx B, Baas T, Zornetzer GA, Haagmans B, Sheahan T, Frieman M, Dyer MD, Teal TH, Proll S, Van Den Brand J, Baric R, Katze MG. Early upregulation of acute respiratory distress syndrome-associated cytokines promotes lethal disease in an aged-mouse model of severe acute respiratory syndrome coronavirus infection (Journal of Virology (2009) 83, 14, (7062-7074)) Journal of Virology. 83: 9022. DOI: 10.1128/Jvi.01322-09  0.734
2008 Sheahan T, Morrison TE, Funkhouser W, Uematsu S, Akira S, Baric RS, Heise MT. MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV. Plos Pathogens. 4: e1000240. PMID 19079579 DOI: 10.1371/Journal.Ppat.1000240  0.663
2008 Chachu KA, LoBue AD, Strong DW, Baric RS, Virgin HW. Immune mechanisms responsible for vaccination against and clearance of mucosal and lymphatic norovirus infection. Plos Pathogens. 4: e1000236. PMID 19079577 DOI: 10.1371/Journal.Ppat.1000236  0.811
2008 Donaldson EF, Sims AC, Baric RS. Systematic assembly and genetic manipulation of the mouse hepatitis virus A59 genome. Methods in Molecular Biology (Clifton, N.J.). 454: 293-315. PMID 19057869 DOI: 10.1007/978-1-59745-181-9_21  0.593
2008 Frieman M, Baric R. Mechanisms of severe acute respiratory syndrome pathogenesis and innate immunomodulation. Microbiology and Molecular Biology Reviews : Mmbr. 72: 672-85, Table of Con. PMID 19052324 DOI: 10.1128/Mmbr.00015-08  0.688
2008 Becker MM, Graham RL, Donaldson EF, Rockx B, Sims AC, Sheahan T, Pickles RJ, Corti D, Johnston RE, Baric RS, Denison MR. Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 19944-9. PMID 19036930 DOI: 10.1073/Pnas.0808116105  0.786
2008 Donaldson EF, Lindesmith LC, Lobue AD, Baric RS. Norovirus pathogenesis: mechanisms of persistence and immune evasion in human populations. Immunological Reviews. 225: 190-211. PMID 18837783 DOI: 10.1111/J.1600-065X.2008.00680.X  0.822
2008 Donaldson EF, Yount B, Sims AC, Burkett S, Pickles RJ, Baric RS. Systematic assembly of a full-length infectious clone of human coronavirus NL63. Journal of Virology. 82: 11948-57. PMID 18818320 DOI: 10.1128/Jvi.01804-08  0.691
2008 Sheahan T, Rockx B, Donaldson E, Corti D, Baric R. Pathways of cross-species transmission of synthetically reconstructed zoonotic severe acute respiratory syndrome coronavirus. Journal of Virology. 82: 8721-32. PMID 18579604 DOI: 10.1128/Jvi.00818-08  0.791
2008 Teunis PF, Moe CL, Liu P, Miller SE, Lindesmith L, Baric RS, Le Pendu J, Calderon RL. Norwalk virus: how infectious is it? Journal of Medical Virology. 80: 1468-76. PMID 18551613 DOI: 10.1002/Jmv.21237  0.338
2008 Lamirande EW, DeDiego ML, Roberts A, Jackson JP, Alvarez E, Sheahan T, Shieh WJ, Zaki SR, Baric R, Enjuanes L, Subbarao K. A live attenuated severe acute respiratory syndrome coronavirus is immunogenic and efficacious in golden Syrian hamsters. Journal of Virology. 82: 7721-4. PMID 18463152 DOI: 10.1128/Jvi.00304-08  0.709
2008 Chachu KA, Strong DW, LoBue AD, Wobus CE, Baric RS, Virgin HW. Antibody is critical for the clearance of murine norovirus infection. Journal of Virology. 82: 6610-7. PMID 18417579 DOI: 10.1128/Jvi.00141-08  0.81
2008 Sparks JS, Donaldson EF, Lu X, Baric RS, Denison MR. A novel mutation in murine hepatitis virus nsp5, the viral 3C-like proteinase, causes temperature-sensitive defects in viral growth and protein processing. Journal of Virology. 82: 5999-6008. PMID 18385240 DOI: 10.1128/Jvi.00203-08  0.675
2008 Pacciarini F, Ghezzi S, Canducci F, Sims A, Sampaolo M, Ferioli E, Clementi M, Poli G, Conaldi PG, Baric R, Vicenzi E. Persistent replication of severe acute respiratory syndrome coronavirus in human tubular kidney cells selects for adaptive mutations in the membrane protein. Journal of Virology. 82: 5137-44. PMID 18367528 DOI: 10.1128/Jvi.00096-08  0.437
2008 Lindesmith LC, Donaldson EF, Lobue AD, Cannon JL, Zheng DP, Vinje J, Baric RS. Mechanisms of GII.4 norovirus persistence in human populations. Plos Medicine. 5: e31. PMID 18271619 DOI: 10.1371/Journal.Pmed.0050031  0.832
2008 Rockx B, Corti D, Donaldson E, Sheahan T, Stadler K, Lanzavecchia A, Baric R. Structural basis for potent cross-neutralizing human monoclonal antibody protection against lethal human and zoonotic severe acute respiratory syndrome coronavirus challenge. Journal of Virology. 82: 3220-35. PMID 18199635 DOI: 10.1128/Jvi.02377-07  0.79
2008 McRoy WC, Baric RS. Amino acid substitutions in the S2 subunit of mouse hepatitis virus variant V51 encode determinants of host range expansion. Journal of Virology. 82: 1414-24. PMID 18032498 DOI: 10.1128/Jvi.01674-07  0.806
2008 Roberts A, Lamirande EW, Vogel L, Jackson JP, Paddock CD, Guarner J, Zaki SR, Sheahan T, Baric R, Subbarao K. Animal models and vaccines for SARS-CoV infection. Virus Research. 133: 20-32. PMID 17499378 DOI: 10.1016/J.Virusres.2007.03.025  0.709
2008 Frieman M, Heise M, Baric R. SARS coronavirus and innate immunity. Virus Research. 133: 101-12. PMID 17451827 DOI: 10.1016/J.Virusres.2007.03.015  0.588
2008 Enjuanes L, Dediego ML, Alvarez E, Deming D, Sheahan T, Baric R. Vaccines to prevent severe acute respiratory syndrome coronavirus-induced disease. Virus Research. 133: 45-62. PMID 17416434 DOI: 10.1016/J.Virusres.2007.01.021  0.8
2008 Lindesmith LC, Donaldson EF, LoBue AD, Cannon JL, Zheng D, Vinje J, Baric RS. Phylogenic Reconstruction of the GII.4 Shell Domain and P1 and P2 Subdomains Plos Medicine. DOI: 10.1371/Journal.Pmed.0050031.G003  0.746
2007 Sheahan T, Rockx B, Donaldson E, Sims A, Pickles R, Corti D, Baric R. Mechanisms of zoonotic severe acute respiratory syndrome coronavirus host range expansion in human airway epithelium. Journal of Virology. 82: 2274-85. PMID 18094188 DOI: 10.1128/Jvi.02041-07  0.792
2007 Wathelet MG, Orr M, Frieman MB, Baric RS. Severe acute respiratory syndrome coronavirus evades antiviral signaling: role of nsp1 and rational design of an attenuated strain. Journal of Virology. 81: 11620-33. PMID 17715225 DOI: 10.1128/JVI.00702-07  0.62
2007 Deming DJ, Graham RL, Denison MR, Baric RS. Processing of open reading frame 1a replicase proteins nsp7 to nsp10 in murine hepatitis virus strain A59 replication. Journal of Virology. 81: 10280-91. PMID 17634238 DOI: 10.1128/Jvi.00017-07  0.735
2007 Zhu Z, Chakraborti S, He Y, Roberts A, Sheahan T, Xiao X, Hensley LE, Prabakaran P, Rockx B, Sidorov IA, Corti D, Vogel L, Feng Y, Kim JO, Wang LF, ... Baric R, et al. Potent cross-reactive neutralization of SARS coronavirus isolates by human monoclonal antibodies. Proceedings of the National Academy of Sciences of the United States of America. 104: 12123-8. PMID 17620608 DOI: 10.1073/Pnas.0701000104  0.763
2007 Frieman M, Yount B, Heise M, Kopecky-Bromberg SA, Palese P, Baric RS. Severe acute respiratory syndrome coronavirus ORF6 antagonizes STAT1 function by sequestering nuclear import factors on the rough endoplasmic reticulum/Golgi membrane. Journal of Virology. 81: 9812-24. PMID 17596301 DOI: 10.1128/Jvi.01012-07  0.556
2007 von Brunn A, Teepe C, Simpson JC, Pepperkok R, Friedel CC, Zimmer R, Roberts R, Baric R, Haas J. Analysis of intraviral protein-protein interactions of the SARS coronavirus ORFeome. Plos One. 2: e459. PMID 17520018 DOI: 10.1371/Journal.Pone.0000459  0.349
2007 Rockx B, Sheahan T, Donaldson E, Harkema J, Sims A, Heise M, Pickles R, Cameron M, Kelvin D, Baric R. Synthetic reconstruction of zoonotic and early human severe acute respiratory syndrome coronavirus isolates that produce fatal disease in aged mice. Journal of Virology. 81: 7410-23. PMID 17507479 DOI: 10.1128/Jvi.00505-07  0.792
2007 Donaldson EF, Graham RL, Sims AC, Denison MR, Baric RS. Analysis of murine hepatitis virus strain A59 temperature-sensitive mutant TS-LA6 suggests that nsp10 plays a critical role in polyprotein processing. Journal of Virology. 81: 7086-98. PMID 17428870 DOI: 10.1128/Jvi.00049-07  0.638
2007 Donaldson EF, Sims AC, Graham RL, Denison MR, Baric RS. Murine hepatitis virus replicase protein nsp10 is a critical regulator of viral RNA synthesis. Journal of Virology. 81: 6356-68. PMID 17392363 DOI: 10.1128/Jvi.02805-06  0.658
2007 Roberts A, Deming D, Paddock CD, Cheng A, Yount B, Vogel L, Herman BD, Sheahan T, Heise M, Genrich GL, Zaki SR, Baric R, Subbarao K. A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice. Plos Pathogens. 3: e5. PMID 17222058 DOI: 10.1371/Journal.Ppat.0030005  0.844
2007 Deming D, Sheahan T, Heise M, Yount B, Davis N, Sims A, Suthar M, Harkema J, Whitmore A, Pickles R, West A, Donaldson E, Curtis K, Johnston R, Baric R. Correction: Vaccine Efficacy in Senescent Mice Challenged with Recombinant SARS-CoV Bearing Epidemic and Zoonotic Spike Variants Plos Medicine. 4: e80. DOI: 10.1371/Journal.Pmed.0040080  0.8
2007 Leon J, Lindesmith L, McNeal E, Baric R, Ailes E, Moe C. Human Norovirus Infection: Genetic and Immune Determinants of Susceptibility and Resistance Clinical Immunology. 123: S29. DOI: 10.1016/J.Clim.2007.03.257  0.35
2006 Deming D, Sheahan T, Heise M, Yount B, Davis N, Sims A, Suthar M, Harkema J, Whitmore A, Pickles R, West A, Donaldson E, Curtis K, Johnston R, Baric R. Vaccine efficacy in senescent mice challenged with recombinant SARS-CoV bearing epidemic and zoonotic spike variants. Plos Medicine. 3: e525. PMID 17194199 DOI: 10.1371/Journal.Pmed.0030525  0.829
2006 Baric RS, Sheahan T, Deming D, Donaldson E, Yount B, Sims AC, Roberts RS, Frieman M, Rockx B. SARS coronavirus vaccine development. Advances in Experimental Medicine and Biology. 581: 553-60. PMID 17037597 DOI: 10.1007/978-0-387-33012-9_101  0.784
2006 Sheahan T, Deming D, Donaldson E, Pickles R, Baric R. Resurrection of an "extinct" SARS-CoV isolate GD03 from late 2003. Advances in Experimental Medicine and Biology. 581: 547-50. PMID 17037596 DOI: 10.1007/978-0-387-33012-9_100  0.825
2006 Sheahan T, Deming D, Donaldson E, Pickles R, Baric R. Resurrection of an "extinct" SARS-CoV isolate GD03 from late 2003. Advances in Experimental Medicine and Biology. 581: 547-50. PMID 17037596 DOI: 10.1007/978-0-387-33012-9_100  0.825
2006 Sims AC, Yount B, Burkett SE, Baric RS, Pickles RJ. SARS CoV replication and pathogenesis in human airway epithelial cultures. Advances in Experimental Medicine and Biology. 581: 535-8. PMID 17037593 DOI: 10.1007/978-0-387-33012-9_97  0.322
2006 McRoy WC, Baric RS. Spike gene determinants of mouse hepatitis virus host range expansion. Advances in Experimental Medicine and Biology. 581: 301-4. PMID 17037548 DOI: 10.1007/978-0-387-33012-9_52  0.822
2006 Frieman MB, Yount B, Sims AC, Deming DJ, Morrison TE, Sparks J, Denison M, Heise M, Baric RS. SARS coronavirus accessory ORFs encode luxury functions. Advances in Experimental Medicine and Biology. 581: 149-52. PMID 17037522 DOI: 10.1007/978-0-387-33012-9_26  0.818
2006 Deming DJ, Graham RL, Denison MR, Baric RS. MHV-A59 ORF1a replicase protein nsp7-nsp10 processing in replication. Advances in Experimental Medicine and Biology. 581: 101-4. PMID 17037513 DOI: 10.1007/978-0-387-33012-9_17  0.705
2006 Graham RL, Sims AC, Baric RS, Denison MR. The nsp2 proteins of mouse hepatitis virus and SARS coronavirus are dispensable for viral replication. Advances in Experimental Medicine and Biology. 581: 67-72. PMID 17037506 DOI: 10.1007/978-0-387-33012-9_10  0.401
2006 Donaldson EF, Sims AC, Deming DJ, Baric RS. Mutational analysis of MHV-A59 replicase protein-nsp10. Advances in Experimental Medicine and Biology. 581: 61-6. PMID 17037505 DOI: 10.1007/978-0-387-33012-9_9  0.752
2006 Yount B, Roberts RS, Lindesmith L, Baric RS. Rewiring the severe acute respiratory syndrome coronavirus (SARS-CoV) transcription circuit: engineering a recombination-resistant genome. Proceedings of the National Academy of Sciences of the United States of America. 103: 12546-51. PMID 16891412 DOI: 10.1073/pnas.0605438103  0.309
2006 LoBue AD, Lindesmith L, Yount B, Harrington PR, Thompson JM, Johnston RE, Moe CL, Baric RS. Multivalent norovirus vaccines induce strong mucosal and systemic blocking antibodies against multiple strains. Vaccine. 24: 5220-34. PMID 16650512 DOI: 10.1016/J.Vaccine.2006.03.080  0.84
2006 Lawler JV, Endy TP, Hensley LE, Garrison A, Fritz EA, Lesar M, Baric RS, Kulesh DA, Norwood DA, Wasieloski LP, Ulrich MP, Slezak TR, Vitalis E, Huggins JW, Jahrling PB, et al. Cynomolgus macaque as an animal model for severe acute respiratory syndrome. Plos Medicine. 3: e149. PMID 16605302 DOI: 10.1371/Journal.Pmed.0030149  0.426
2006 Baccaglini L, Schoenbach VJ, Poole C, McKaig RG, Ibrahim J, Baric RS, Wiesen C. Association between herpes simplex virus type 1 and Helicobacter pylori in US adolescents. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics. 101: 63-9. PMID 16360609 DOI: 10.1016/J.Tripleo.2004.12.018  0.341
2005 Sims AC, Baric RS, Yount B, Burkett SE, Collins PL, Pickles RJ. Severe acute respiratory syndrome coronavirus infection of human ciliated airway epithelia: role of ciliated cells in viral spread in the conducting airways of the lungs. Journal of Virology. 79: 15511-24. PMID 16306622 DOI: 10.1128/Jvi.79.24.15511-15524.2005  0.447
2005 Yount B, Roberts RS, Sims AC, Deming D, Frieman MB, Sparks J, Denison MR, Davis N, Baric RS. Severe acute respiratory syndrome coronavirus group-specific open reading frames encode nonessential functions for replication in cell cultures and mice. Journal of Virology. 79: 14909-22. PMID 16282490 DOI: 10.1128/Jvi.79.23.14909-14922.2005  0.802
2005 Graham RL, Sims AC, Brockway SM, Baric RS, Denison MR. The nsp2 replicase proteins of murine hepatitis virus and severe acute respiratory syndrome coronavirus are dispensable for viral replication. Journal of Virology. 79: 13399-411. PMID 16227261 DOI: 10.1128/Jvi.79.21.13399-13411.2005  0.44
2005 Rockx B, Baric RS, de Grijs I, Duizer E, Koopmans MP. Characterization of the homo- and heterotypic immune responses after natural norovirus infection. Journal of Medical Virology. 77: 439-46. PMID 16173019 DOI: 10.1002/Jmv.20473  0.405
2005 Sperry SM, Kazi L, Graham RL, Baric RS, Weiss SR, Denison MR. Single-amino-acid substitutions in open reading frame (ORF) 1b-nsp14 and ORF 2a proteins of the coronavirus mouse hepatitis virus are attenuating in mice. Journal of Virology. 79: 3391-400. PMID 15731233 DOI: 10.1128/Jvi.79.6.3391-3400.2005  0.407
2005 Baric RS, Sims AC. Development of mouse hepatitis virus and SARS-CoV infectious cDNA constructs Current Topics in Microbiology and Immunology. 287: 229-252. PMID 15609514  0.345
2004 Curtis KM, Yount B, Sims AC, Baric RS. Reverse genetic analysis of the transcription regulatory sequence of the coronavirus transmissible gastroenteritis virus. Journal of Virology. 78: 6061-6. PMID 15141005 DOI: 10.1128/Jvi.78.11.6061-6066.2004  0.578
2004 Denison MR, Yount B, Brockway SM, Graham RL, Sims AC, Lu X, Baric RS. Cleavage between replicase proteins p28 and p65 of mouse hepatitis virus is not required for virus replication. Journal of Virology. 78: 5957-65. PMID 15140993 DOI: 10.1128/Jvi.78.11.5957-5965.2004  0.369
2004 Harrington PR, Vinjé J, Moe CL, Baric RS. Norovirus capture with histo-blood group antigens reveals novel virus-ligand interactions. Journal of Virology. 78: 3035-45. PMID 14990722 DOI: 10.1128/Jvi.78.6.3035-3045.2004  0.679
2003 Shieh YC, Baric RS, Woods JW, Calci KR. Molecular surveillance of enterovirus and norwalk-like virus in oysters relocated to a municipal-sewage-impacted gulf estuary. Applied and Environmental Microbiology. 69: 7130-6. PMID 14660358 DOI: 10.1128/Aem.69.12.7130-7136.2003  0.358
2003 Yount B, Curtis KM, Fritz EA, Hensley LE, Jahrling PB, Prentice E, Denison MR, Geisbert TW, Baric RS. Reverse genetics with a full-length infectious cDNA of severe acute respiratory syndrome coronavirus. Proceedings of the National Academy of Sciences of the United States of America. 100: 12995-3000. PMID 14569023 DOI: 10.1073/Pnas.1735582100  0.671
2003 Lindesmith L, Moe C, Marionneau S, Ruvoen N, Jiang X, Lindblad L, Stewart P, LePendu J, Baric R. Human susceptibility and resistance to Norwalk virus infection. Nature Medicine. 9: 548-53. PMID 12692541 DOI: 10.1038/Nm860  0.449
2002 Harrington PR, Lindesmith L, Yount B, Moe CL, Baric RS. Binding of Norwalk virus-like particles to ABH histo-blood group antigens is blocked by antisera from infected human volunteers or experimentally vaccinated mice. Journal of Virology. 76: 12335-43. PMID 12414974 DOI: 10.1128/Jvi.76.23.12335-12343.2002  0.709
2002 Yount B, Denison MR, Weiss SR, Baric RS. Systematic assembly of a full-length infectious cDNA of mouse hepatitis virus strain A59. Journal of Virology. 76: 11065-78. PMID 12368349 DOI: 10.1128/Jvi.76.21.11065-11078.2002  0.391
2002 Baric RS, Yount B, Lindesmith L, Harrington PR, Greene SR, Tseng FC, Davis N, Johnston RE, Klapper DG, Moe CL. Expression and self-assembly of norwalk virus capsid protein from venezuelan equine encephalitis virus replicons. Journal of Virology. 76: 3023-30. PMID 11861868 DOI: 10.1128/Jvi.76.6.3023-3030.2002  0.658
2002 Curtis KM, Yount B, Baric RS. Heterologous gene expression from transmissible gastroenteritis virus replicon particles. Journal of Virology. 76: 1422-34. PMID 11773416 DOI: 10.1128/Jvi.76.3.1422-1434.2002  0.588
2002 Harrington PR, Yount B, Johnston RE, Davis N, Moe C, Baric RS. Systemic, mucosal, and heterotypic immune induction in mice inoculated with Venezuelan equine encephalitis replicons expressing Norwalk virus-like particles. Journal of Virology. 76: 730-42. PMID 11752163 DOI: 10.1128/Jvi.76.2.730-742.2002  0.725
2001 Curtis KM, Yount B, Baric RS. A simple strategy to assemble infectious RNA and DNA clones. Advances in Experimental Medicine and Biology. 494: 475-81. PMID 11774510 DOI: 10.1007/978-1-4615-1325-4_69  0.557
2001 Baric RS, Curtis KM, Yount B. MHV subgenomic negative strand function. Advances in Experimental Medicine and Biology. 494: 459-65. PMID 11774508 DOI: 10.1007/978-1-4615-1325-4_67  0.504
2000 Yount B, Curtis KM, Baric RS. Strategy for systematic assembly of large RNA and DNA genomes: transmissible gastroenteritis virus model. Journal of Virology. 74: 10600-11. PMID 11044104 DOI: 10.1128/Jvi.74.22.10600-10611.2000  0.618
2000 Carol Shieh YS, Monroe SS, Fankhauser RL, Langlois GW, Burkhardt W, Baric RS. Detection of Norwalk-like virus in shellfish implicated in illness Journal of Infectious Diseases. 181. PMID 10804149 DOI: 10.1086/315578  0.397
2000 Baric RS, Yount B. Subgenomic negative-strand RNA function during mouse hepatitis virus infection Journal of Virology. 74: 4039-4046. PMID 10756015 DOI: 10.1128/Jvi.74.9.4039-4046.2000  0.317
1999 Shieh YSC, Calci KR, Baric RS. A method to detect low levels of enteric viruses in contaminated oysters Applied and Environmental Microbiology. 65: 4709-4714. PMID 10543775 DOI: 10.1128/Aem.65.11.4709-4714.1999  0.361
1999 Parks CG, Moe CL, Rhodes D, Lima A, Barrett L, Tseng F, Baric R, Talal A, Guerrant R. Genomic diversity of "Norwalk like viruses" (NLVs): pediatric infections in a Brazilian shantytown. Journal of Medical Virology. 58: 426-34. PMID 10421412 DOI: 10.1002/(Sici)1096-9071(199908)58:4<426::Aid-Jmv17>3.0.Co;2-K  0.383
1999 Baric RS, Sullivan E, Hensley L, Yount B, Chen W. Persistent infection promotes cross-species transmissibility of mouse hepatitis virus Journal of Virology. 73: 638-649. PMID 9847369 DOI: 10.1128/Jvi.73.1.638-649.1999  0.466
1998 Chen W, Yount B, Hensley L, Baric RS. Receptor homologue scanning functions in the maintenance of MHV-A59 persistence in vitro Advances in Experimental Medicine and Biology. 440: 743-750. PMID 9782353 DOI: 10.1007/978-1-4615-5331-1_96  0.389
1998 Hensley LE, Baric RS. Human biliary glycoproteins function as receptors for interspecies transfer of mouse hepatitis virus Advances in Experimental Medicine and Biology. 440: 43-52. PMID 9782263 DOI: 10.1007/978-1-4615-5331-1_6  0.389
1998 Hensley LE, Holmes KV, Beauchemin N, Baric RS. Virus-receptor interactions and interspecies transfer of a mouse hepatitis virus Advances in Experimental Medicine and Biology. 440: 33-41. PMID 9782262 DOI: 10.1007/978-1-4615-5331-1_5  0.424
1998 Stalcup RP, Baric RS, Leibowitz JL. Genetic complementation among three panels of mouse hepatitis virus gene 1 mutants Virology. 241: 112-121. PMID 9454722 DOI: 10.1006/Viro.1997.8957  0.308
1997 Shieh YSC, Baric RS, Sobsey MD. Detection of low levels of enteric viruses in metropolitan and airplane sewage Applied and Environmental Microbiology. 63: 4401-4407. PMID 9361427 DOI: 10.1128/Aem.63.11.4401-4407.1997  0.348
1997 Chen W, Madden VJ, Bagnell CR, Baric RS. Host-derived intracellular immunization against mouse hepatitis virus infection Virology. 228: 318-332. PMID 9123839 DOI: 10.1006/Viro.1996.8402  0.412
1997 Baric RS, Yount B, Hensley L, Peel SA, Chen W. Episodic evolution mediates interspecies transfer of a murine coronavirus Journal of Virology. 71: 1946-1955. PMID 9032326 DOI: 10.1128/Jvi.71.3.1946-1955.1997  0.425
1996 Chen W, Baric RS. Molecular anatomy of mouse hepatitis virus persistence: Coevolution of increased host cell resistance and virus virulence Journal of Virology. 70: 3947-3960. PMID 8648732 DOI: 10.1128/Jvi.70.6.3947-3960.1996  0.415
1995 Chen W, Baric RS. Evolution and persistence mechanisms of mouse hepatitis virus Advances in Experimental Medicine and Biology. 380: 63-71. PMID 8830548 DOI: 10.1007/978-1-4615-1899-0_9  0.373
1995 Baric RS, Fu K, Chen W, Yount B. High recombination and mutation rates in mouse hepatitis virus suggest that coronaviruses may be potentially important emerging viruses Advances in Experimental Medicine and Biology. 380: 571-576. PMID 8830544 DOI: 10.1007/978-1-4615-1899-0_91  0.458
1995 Alexander LK, Keene BW, Baric RS. Echocardiographic changes following rabbit coronavirus infection Advances in Experimental Medicine and Biology. 380: 113-115. PMID 8830464 DOI: 10.1007/978-1-4615-1899-0_18  0.38
1995 Chen W, Baric RS. Function of a 5′-end genomic RNA mutation that evolves during persistent mouse hepatitis virus infection in vitro Journal of Virology. 69: 7529-7540. PMID 7494259 DOI: 10.1128/Jvi.69.12.7529-7540.1995  0.375
1994 Baker SC, Gao H, Baric RS. Altered proteolytic processing of the polymerase polyprotein in RNA(-) temperature sensitive mutants of murine coronavirus Advances in Experimental Medicine and Biology. 342: 215-219. PMID 8209733 DOI: 10.1007/978-1-4615-2996-5_34  0.311
1994 Schaad MC, Baric RS. Genetics of mouse hepatitis virus transcription: Evidence that subgenomic negative strands are functional templates Journal of Virology. 68: 8169-8179. PMID 7966608 DOI: 10.1128/Jvi.68.12.8169-8179.1994  0.316
1994 Fu K, Baric RS. Map locations of mouse hepatitis virus temperature-sensitive mutants: Confirmation of variable rates of recombination Journal of Virology. 68: 7458-7466. PMID 7933129 DOI: 10.1128/Jvi.68.11.7458-7466.1994  0.352
1993 Schaad MC, Baric RS. Evidence for New Transcriptional Units Encoded at the 3′ End of the Mouse Hepatitis Virus Genome Virology. 196: 190-198. PMID 8395114 DOI: 10.1006/Viro.1993.1467  0.343
1993 Hughes SA, Denison MR, Bonilla P, Leibowitz JL, Baric RS, Weiss SR. A newly identified MHV-A59 ORF1a polypeptide p65 is temperature sensitive in two RNA negative mutants. Advances in Experimental Medicine and Biology. 342: 221-6. PMID 8209734 DOI: 10.1007/978-1-4615-2996-5_35  0.308
1992 Alexander LK, David Small J, Edwards S, Baric RS. An experimental model for dilated cardiomyopathy after rabbit coronavirus infection Journal of Infectious Diseases. 166: 978-985. PMID 1328411 DOI: 10.1093/Infdis/166.5.978  0.309
1992 Fu K, Baric RS. Evidence for variable rates of recombination in the MHV genome Virology. 189: 88-102. PMID 1318616 DOI: 10.1016/0042-6822(92)90684-H  0.328
1991 Carol Shieh YS, Baric RS, Sobsey MD, Ticehurst J, Miele TA, DeLeon R, Walter R. Detection of hepatitis A virus and other enteroviruses in water by ssRNA probes Journal of Virological Methods. 31: 119-136. PMID 1849914 DOI: 10.1016/0166-0934(91)90150-X  0.321
1990 Baric RS, Fu K, Schaad MC, Stohlman SA. Establishing a genetic recombination map for murine coronavirus strain A59 complementation groups Virology. 177: 646-656. PMID 2164728 DOI: 10.1016/0042-6822(90)90530-5  0.394
1990 Schaad MC, Stohlman SA, Egbert J, Lum K, Fu K, Wei T, Baric RS. Genetics of mouse hepatitis virus transcription: identification of cistrons which may function in positive and negative strand RNA synthesis. Virology. 177: 634-45. PMID 2164727 DOI: 10.1016/0042-6822(90)90529-Z  0.311
1990 Baric RS, Edwards S, Small JD. Rabbit dilated cardiomyopathy Advances in Experimental Medicine and Biology. 276: 511-518. PMID 1966443 DOI: 10.1007/978-1-4684-5823-7_71  0.333
1990 Baric RS, Schaad MC, Wei T, Fu K, Lum K, Shieh C, Stohlman SA. Murine coronavirus temperature sensitive mutants Advances in Experimental Medicine and Biology. 276: 349-356. PMID 1966422 DOI: 10.1007/978-1-4684-5823-7_47  0.385
1988 Baric RS, Nelson GW, Fleming JO, Deans RJ, Keck JG, Casteel N, Stohlman SA. Interactions between coronavirus nucleocapsid protein and viral RNAs: Implications for viral transcription Journal of Virology. 62: 4280-4287. PMID 2845140 DOI: 10.1128/Jvi.62.11.4280-4287.1988  0.345
1987 Baric RS, Shieh CK, Stohlman SA, Lai MM. Studies into the mechanism of MHV transcription Advances in Experimental Medicine and Biology. 218: 137-149. PMID 2829521  0.398
1985 Lai MM, Baric RS, Makino S, Keck JG, Egbert J, Leibowitz JL, Stohlman SA. Recombination between nonsegmented RNA genomes of murine coronaviruses. Journal of Virology. 56: 449-56. PMID 2997467 DOI: 10.1128/Jvi.56.2.449-456.1985  0.521
1984 Lai MM, Baric RS, Brayton PR, Stohlman SA. Studies on the mechanism of RNA synthesis of a murine coronavirus Advances in Experimental Medicine and Biology. 173: 187-200. PMID 6331110 DOI: 10.1007/978-1-4615-9373-7_19  0.464
1984 Olmsted RA, Baric RS, Sawyer BA, Johnston RE. Sindbis virus mutants selected for rapid growth in cell culture display attenuated virulence in animals. Science (New York, N.Y.). 225: 424-7. PMID 6204381 DOI: 10.1126/Science.6204381  0.416
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