Year |
Citation |
Score |
2023 |
Liu Q, Pillus L, Petty EL. Functional tug of war between kinases, phosphatases, and the Gcn5 acetyltransferase in chromatin and cell cycle checkpoint controls. G3 (Bethesda, Md.). PMID 36772957 DOI: 10.1093/g3journal/jkad021 |
0.432 |
|
2020 |
Petty EL, Pillus L. Cell cycle roles for GCN5 revealed through genetic suppression. Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms. 194625. PMID 32798737 DOI: 10.1016/J.Bbagrm.2020.194625 |
0.531 |
|
2020 |
Li Y, Jiang Y, Paxman J, O'Laughlin R, Klepin S, Zhu Y, Pillus L, Tsimring LS, Hasty J, Hao N. A programmable fate decision landscape underlies single-cell aging in yeast. Science (New York, N.Y.). 369: 325-329. PMID 32675375 DOI: 10.1126/Science.Aax9552 |
0.337 |
|
2019 |
Hao N, Li Y, Jiang Y, Paxman J, O’Laughlin R, Pillus L, Tsimring L, Hasty J. WADDINGTON’S LANDSCAPE OF CELL AGING Innovation in Aging. 3: S208-S208. DOI: 10.1093/Geroni/Igz038.755 |
0.328 |
|
2018 |
Petty EL, Evpak M, Pillus L. Connecting GCN5's centromeric SAGA to the mitotic tension-sensing checkpoint. Molecular Biology of the Cell. mbcE17120701. PMID 29995571 DOI: 10.1091/Mbc.E17-12-0701 |
0.426 |
|
2017 |
Li Y, Jin M, O'Laughlin R, Bittihn P, Tsimring LS, Pillus L, Hasty J, Hao N. Multigenerational silencing dynamics control cell aging. Proceedings of the National Academy of Sciences of the United States of America. 114: 11253-11258. PMID 29073021 DOI: 10.1073/Pnas.1703379114 |
0.346 |
|
2017 |
Searle NE, Pillus L. Critical genomic regulation mediated by Enhancer of Polycomb. Current Genetics. PMID 28884217 DOI: 10.1007/S00294-017-0742-3 |
0.501 |
|
2017 |
Marquez-Lona EM, Torres-Machorro AL, Gonzales FR, Pillus L, Patrick GN. Phosphorylation of the 19S regulatory particle ATPase subunit, Rpt6, modifies susceptibility to proteotoxic stress and protein aggregation. Plos One. 12: e0179893. PMID 28662109 DOI: 10.1371/Journal.Pone.0179893 |
0.38 |
|
2017 |
Mason AG, Garza RM, McCormick MA, Patel B, Kennedy BK, Pillus L, La Spada AR. The replicative lifespan-extending deletion of SGF73 results in altered ribosomal gene expression in yeast. Aging Cell. PMID 28568901 DOI: 10.1111/Acel.12611 |
0.506 |
|
2017 |
Searle NE, Torres-Machorro AL, Pillus L. Chromatin Regulation by the NuA4 Acetyltransferase Complex Is Mediated by Essential Interactions Between Enhancer of Polycomb (Epl1) and Esa1. Genetics. PMID 28108589 DOI: 10.1534/Genetics.116.197830 |
0.572 |
|
2016 |
Petty EL, Lafon A, Tomlinson SL, Mendelsohn BA, Pillus L. Promotion of Cell Viability and Histone Gene Expression by the Acetyltransferase Gcn5 and the Protein Phosphatase PP2A in Saccharomyces cerevisiae. Genetics. PMID 27317677 DOI: 10.1534/Genetics.116.189506 |
0.623 |
|
2016 |
Su XB, Pillus L. Functions for diverse metabolic activities in heterochromatin. Proceedings of the National Academy of Sciences of the United States of America. PMID 26936955 DOI: 10.1073/Pnas.1518707113 |
0.503 |
|
2015 |
Torres-Machorro AL, Clark LG, Chang CS, Pillus L. The Set3 Complex Antagonizes the MYST Acetyltransferase Esa1 in the DNA Damage Response. Molecular and Cellular Biology. 35: 3714-25. PMID 26303527 DOI: 10.1128/Mcb.00298-15 |
0.693 |
|
2015 |
Torres-Machorro AL, Aris JP, Pillus L. A moonlighting metabolic protein influences repair at DNA double-stranded breaks. Nucleic Acids Research. 43: 1646-58. PMID 25628362 DOI: 10.1093/Nar/Gku1405 |
0.501 |
|
2014 |
Basnet H, Su XB, Tan Y, Meisenhelder J, Merkurjev D, Ohgi KA, Hunter T, Pillus L, Rosenfeld MG. Tyrosine phosphorylation of histone H2A by CK2 regulates transcriptional elongation. Nature. 516: 267-71. PMID 25252977 DOI: 10.1038/Nature13736 |
0.572 |
|
2014 |
McCormick MA, Mason AG, Guyenet SJ, Dang W, Garza RM, Ting MK, Moller RM, Berger SL, Kaeberlein M, Pillus L, La Spada AR, Kennedy BK. The SAGA histone deubiquitinase module controls yeast replicative lifespan via Sir2 interaction. Cell Reports. 8: 477-86. PMID 25043177 DOI: 10.1016/J.Celrep.2014.06.037 |
0.506 |
|
2014 |
Torres-Machorro AL, Pillus L. Bypassing the requirement for an essential MYST acetyltransferase. Genetics. 197: 851-63. PMID 24831819 DOI: 10.1534/Genetics.114.165894 |
0.536 |
|
2014 |
Eustice M, Pillus L. Unexpected function of the glucanosyltransferase Gas1 in the DNA damage response linked to histone H3 acetyltransferases in Saccharomyces cerevisiae. Genetics. 196: 1029-39. PMID 24532730 DOI: 10.1534/Genetics.113.158824 |
0.531 |
|
2013 |
Petty E, Pillus L. Balancing chromatin remodeling and histone modifications in transcription. Trends in Genetics : Tig. 29: 621-9. PMID 23870137 DOI: 10.1016/J.Tig.2013.06.006 |
0.582 |
|
2013 |
Chen M, Licon K, Otsuka R, Pillus L, Ideker T. Decoupling epigenetic and genetic effects through systematic analysis of gene position. Cell Reports. 3: 128-37. PMID 23291096 DOI: 10.1016/J.Celrep.2012.12.003 |
0.516 |
|
2013 |
Garza R, Pillus L. STUbLs in chromatin and genome stability. Biopolymers. 99: 146-54. PMID 23175389 DOI: 10.1002/Bip.22125 |
0.532 |
|
2012 |
Lafon A, Petty E, Pillus L. Functional antagonism between Sas3 and Gcn5 acetyltransferases and ISWI chromatin remodelers. Plos Genetics. 8: e1002994. PMID 23055944 DOI: 10.1371/Journal.Pgen.1002994 |
0.564 |
|
2012 |
Chang CS, Clarke A, Pillus L. Suppression analysis of esa1 mutants in Saccharomyces cerevisiae links NAB3 to transcriptional silencing and nucleolar functions. G3 (Bethesda, Md.). 2: 1223-32. PMID 23050233 DOI: 10.1534/G3.112.003558 |
0.647 |
|
2010 |
Scott EM, Pillus L. Homocitrate synthase connects amino acid metabolism to chromatin functions through Esa1 and DNA damage. Genes & Development. 24: 1903-13. PMID 20810648 DOI: 10.1101/Gad.1935910 |
0.511 |
|
2010 |
Bulfer SL, Scott EM, Pillus L, Trievel RC. Structural basis for L-lysine feedback inhibition of homocitrate synthase. The Journal of Biological Chemistry. 285: 10446-53. PMID 20089861 DOI: 10.1074/Jbc.M109.094383 |
0.347 |
|
2010 |
Koch MR, Pillus L. Silent chromatin formation and regulation in the yeast saccharomyces cerevisiae Handbook of Cell Signaling, 2/E. 3: 2427-2436. DOI: 10.1016/B978-0-12-374145-5.00290-4 |
0.761 |
|
2009 |
Bulfer SL, Scott EM, Couture JF, Pillus L, Trievel RC. Crystal structure and functional analysis of homocitrate synthase, an essential enzyme in lysine biosynthesis. The Journal of Biological Chemistry. 284: 35769-80. PMID 19776021 DOI: 10.1016/J.Bpj.2009.12.2446 |
0.326 |
|
2009 |
Jacobson S, Pillus L. The SAGA subunit Ada2 functions in transcriptional silencing. Molecular and Cellular Biology. 29: 6033-45. PMID 19737915 DOI: 10.1128/Mcb.00542-09 |
0.596 |
|
2009 |
Chang CS, Pillus L. Collaboration between the essential Esa1 acetyltransferase and the Rpd3 deacetylase is mediated by H4K12 histone acetylation in Saccharomyces cerevisiae. Genetics. 183: 149-60. PMID 19596907 DOI: 10.1534/Genetics.109.103846 |
0.735 |
|
2009 |
Koch MR, Pillus L. The glucanosyltransferase Gas1 functions in transcriptional silencing. Proceedings of the National Academy of Sciences of the United States of America. 106: 11224-9. PMID 19541632 DOI: 10.1073/Pnas.0900809106 |
0.777 |
|
2009 |
Mak HC, Pillus L, Ideker T. Dynamic reprogramming of transcription factors to and from the subtelomere. Genome Research. 19: 1014-25. PMID 19372386 DOI: 10.1101/Gr.084178.108 |
0.479 |
|
2009 |
Kennedy EJ, Yang J, Pillus L, Taylor SS, Ghosh G. Identifying critical non-catalytic residues that modulate protein kinase A activity. Plos One. 4: e4746. PMID 19270744 DOI: 10.1371/Journal.Pone.0004746 |
0.367 |
|
2008 |
Pillus L. MYSTs mark chromatin for chromosomal functions. Current Opinion in Cell Biology. 20: 326-33. PMID 18511253 DOI: 10.1016/J.Ceb.2008.04.009 |
0.497 |
|
2008 |
Darst RP, Garcia SN, Koch MR, Pillus L. Slx5 promotes transcriptional silencing and is required for robust growth in the absence of Sir2. Molecular and Cellular Biology. 28: 1361-72. PMID 18086879 DOI: 10.1128/Mcb.01291-07 |
0.772 |
|
2008 |
Kennedy EJ, Ghosh G, Pillus L. Identification of functionally distinct regions that mediate biological activity of the protein kinase a homolog Tpk2. The Journal of Biological Chemistry. 283: 1084-93. PMID 17971450 DOI: 10.1074/Jbc.M704028200 |
0.343 |
|
2008 |
Darst RP, Garcia SN, Koch MR, Pillus L. Slx5 promotes transcriptional silencing and is required for robust growth in the absence of Sir2 (Molecular and Cellular Biology (2008) 28, 4, (1361-1372)) Molecular and Cellular Biology. 28: 7532. DOI: 10.1128/MCB.01664-08 |
0.697 |
|
2007 |
Allis CD, Berger SL, Cote J, Dent S, Jenuwien T, Kouzarides T, Pillus L, Reinberg D, Shi Y, Shiekhattar R, Shilatifard A, Workman J, Zhang Y. New nomenclature for chromatin-modifying enzymes. Cell. 131: 633-6. PMID 18022353 DOI: 10.1016/J.Cell.2007.10.039 |
0.314 |
|
2007 |
Lafon A, Chang CS, Scott EM, Jacobson SJ, Pillus L. MYST opportunities for growth control: yeast genes illuminate human cancer gene functions. Oncogene. 26: 5373-84. PMID 17694079 DOI: 10.1038/Sj.Onc.1210606 |
0.698 |
|
2006 |
Wilson JM, Le VQ, Zimmerman C, Marmorstein R, Pillus L. Nuclear export modulates the cytoplasmic Sir2 homologue Hst2. Embo Reports. 7: 1247-51. PMID 17110954 DOI: 10.1038/Sj.Embor.7400829 |
0.659 |
|
2006 |
Ruault M, Pillus L. Chromatin-modifiying enzymes are essential when the Saccharomyces cerevisiae morphogenesis checkpoint is constitutively activated. Genetics. 174: 1135-49. PMID 16951088 DOI: 10.1534/Genetics.106.059873 |
0.486 |
|
2006 |
Clarke AS, Samal E, Pillus L. Distinct roles for the essential MYST family HAT Esa1p in transcriptional silencing. Molecular Biology of the Cell. 17: 1744-57. PMID 16436512 DOI: 10.1091/Mbc.E05-07-0613 |
0.561 |
|
2005 |
Kennedy EJ, Pillus L, Ghosh G. Pho5p and newly identified nucleotide pyrophosphatases/ phosphodiesterases regulate extracellular nucleotide phosphate metabolism in Saccharomyces cerevisiae. Eukaryotic Cell. 4: 1892-901. PMID 16278456 DOI: 10.1128/Ec.4.11.1892-1901.2005 |
0.351 |
|
2005 |
Pillus L, Rine J. SIR1 and the origin of epigenetic states in Saccharomyces cerevisiae. Cold Spring Harbor Symposia On Quantitative Biology. 69: 259-65. PMID 16117657 DOI: 10.1101/Sqb.2004.69.259 |
0.36 |
|
2005 |
Wirén M, Silverstein RA, Sinha I, Walfridsson J, Lee HM, Laurenson P, Pillus L, Robyr D, Grunstein M, Ekwall K. Genomewide analysis of nucleosome density histone acetylation and HDAC function in fission yeast. The Embo Journal. 24: 2906-18. PMID 16079916 DOI: 10.1038/Sj.Emboj.7600758 |
0.511 |
|
2005 |
Lo WS, Gamache ER, Henry KW, Yang D, Pillus L, Berger SL. Histone H3 phosphorylation can promote TBP recruitment through distinct promoter-specific mechanisms. The Embo Journal. 24: 997-1008. PMID 15719021 DOI: 10.1038/Sj.Emboj.7600577 |
0.58 |
|
2005 |
Freeman-Cook LL, Gómez EB, Spedale EJ, Marlett J, Forsburg SL, Pillus L, Laurenson P. Conserved locus-specific silencing functions of Schizosaccharomyces pombe sir2+. Genetics. 169: 1243-60. PMID 15545655 DOI: 10.1534/Genetics.104.032714 |
0.537 |
|
2004 |
Jacobson S, Pillus L. Molecular requirements for gene expression mediated by targeted histone acetyltransferases. Molecular and Cellular Biology. 24: 6029-39. PMID 15199156 DOI: 10.1128/Mcb.24.13.6029-6039.2004 |
0.535 |
|
2004 |
Jacobson SJ, Laurenson PM, Pillus L. Functional analyses of chromatin modifications in yeast. Methods in Enzymology. 377: 3-55. PMID 14979016 DOI: 10.1016/S0076-6879(03)77001-3 |
0.511 |
|
2003 |
Murphy GA, Spedale EJ, Powell ST, Pillus L, Schultz SC, Chen L. The Sir4 C-terminal coiled coil is required for telomeric and mating type silencing in Saccharomyces cerevisiae. Journal of Molecular Biology. 334: 769-80. PMID 14636601 DOI: 10.1016/J.Jmb.2003.09.066 |
0.365 |
|
2003 |
Henry KW, Wyce A, Lo WS, Duggan LJ, Emre NC, Kao CF, Pillus L, Shilatifard A, Osley MA, Berger SL. Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8. Genes & Development. 17: 2648-63. PMID 14563679 DOI: 10.1101/Gad.1144003 |
0.582 |
|
2003 |
Clements A, Poux AN, Lo WS, Pillus L, Berger SL, Marmorstein R. Structural basis for histone and phosphohistone binding by the GCN5 histone acetyltransferase. Molecular Cell. 12: 461-73. PMID 14536085 DOI: 10.1016/S1097-2765(03)00288-0 |
0.54 |
|
2003 |
Parsons XH, Garcia SN, Pillus L, Kadonaga JT. Histone deacetylation by Sir2 generates a transcriptionally repressed nucleoprotein complex. Proceedings of the National Academy of Sciences of the United States of America. 100: 1609-14. PMID 12571358 DOI: 10.1073/Pnas.0434064100 |
0.563 |
|
2002 |
Garcia SN, Pillus L. A unique class of conditional sir2 mutants displays distinct silencing defects in Saccharomyces cerevisiae. Genetics. 162: 721-36. PMID 12399383 |
0.45 |
|
2001 |
Howe L, Auston D, Grant P, John S, Cook RG, Workman JL, Pillus L. Histone H3 specific acetyltransferases are essential for cell cycle progression. Genes & Development. 15: 3144-54. PMID 11731478 DOI: 10.1101/Gad.931401 |
0.441 |
|
2001 |
Dutnall RN, Pillus L. Deciphering NAD-dependent deacetylases. Cell. 105: 161-4. PMID 11336664 DOI: 10.1016/S0092-8674(01)00305-1 |
0.379 |
|
2000 |
Landry J, Sutton A, Tafrov ST, Heller RC, Stebbins J, Pillus L, Sternglanz R. The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases Proceedings of the National Academy of Sciences of the United States of America. 97: 5807-5811. PMID 10811920 DOI: 10.1073/Pnas.110148297 |
0.581 |
|
2000 |
Stone EM, Heun P, Laroche T, Pillus L, Gasser SM. MAP kinase signaling induces nuclear reorganization in budding yeast. Current Biology : Cb. 10: 373-82. PMID 10753745 DOI: 10.1016/S0960-9822(00)00413-9 |
0.387 |
|
2000 |
Nislow C, Ray E, Pillus L. SET1, a yeast member of the trithorax family, functions in transcriptional silencing and diverse cellular processes. Molecular Biology of the Cell. 8: 2421-36. PMID 9398665 DOI: 10.1091/Mbc.8.12.2421 |
0.462 |
|
1999 |
Freeman-Cook LL, Sherman JM, Brachmann CB, Allshire RC, Boeke JD, Pillus L. The Schizosaccharomyces pombe hst4(+) gene is a SIR2 homologue with silencing and centromeric functions. Molecular Biology of the Cell. 10: 3171-86. PMID 10512858 DOI: 10.1091/Mbc.10.10.3171 |
0.534 |
|
1999 |
Allard S, Utley RT, Savard J, Clarke A, Grant P, Brandl CJ, Pillus L, Workman JL, Côté J. NuA4, an essential transcription adaptor/histone H4 acetyltransferase complex containing Esa1p and the ATM-related cofactor Tra1p. The Embo Journal. 18: 5108-19. PMID 10487762 DOI: 10.1093/Emboj/18.18.5108 |
0.586 |
|
1999 |
Sherman JM, Stone EM, Freeman-Cook LL, Brachmann CB, Boeke JD, Pillus L. The conserved core of a human SIR2 homologue functions in yeast silencing. Molecular Biology of the Cell. 10: 3045-59. PMID 10473645 DOI: 10.1091/Mbc.10.9.3045 |
0.518 |
|
1999 |
Garcia SN, Pillus L. Net results of nucleolar dynamics. Cell. 97: 825-8. PMID 10399910 DOI: 10.1016/S0092-8674(00)80794-1 |
0.395 |
|
1999 |
Jacobson S, Pillus L. Modifying chromatin and concepts of cancer. Current Opinion in Genetics & Development. 9: 175-84. PMID 10322138 DOI: 10.1016/S0959-437X(99)80027-6 |
0.512 |
|
1999 |
Clarke AS, Lowell JE, Jacobson SJ, Pillus L. Esa1p is an essential histone acetyltransferase required for cell cycle progression Molecular and Cellular Biology. 19: 2515-2526. PMID 10082517 DOI: 10.1128/Mcb.19.4.2515 |
0.611 |
|
1999 |
Allard S, Utley RT, Savard J, Clarke A, Grant P, Brandl CJ, Pillus L, Workman JL, Côté J. The NuA4 transcription activation/histone H4 acetyltransferase complex contains the essential Esa1 protein as the catalytic subunit and the essential ATM-related cofactor Tra1p Biochemistry and Cell Biology. 77: 383. DOI: 10.1139/O99-903 |
0.456 |
|
1998 |
Stone EM, Pillus L. Silent chromatin in yeast: an orchestrated medley featuring Sir3p [corrected]. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 20: 30-40. PMID 9504045 DOI: 10.1002/(Sici)1521-1878(199801)20:1<30::Aid-Bies6>3.0.Co;2-W |
0.59 |
|
1998 |
Lowell JE, Pillus L. Telomere tales: chromatin, telomerase and telomere function in Saccharomyces cerevisiae. Cellular and Molecular Life Sciences : Cmls. 54: 32-49. PMID 9487385 DOI: 10.1007/S000180050123 |
0.531 |
|
1997 |
Sherman JM, Pillus L. An uncertain silence. Trends in Genetics : Tig. 13: 308-13. PMID 9260516 DOI: 10.1016/S0168-9525(97)01198-0 |
0.558 |
|
1997 |
Laible G, Wolf A, Dorn R, Reuter G, Nislow C, Lebersorger A, Popkin D, Pillus L, Jenuwein T. Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres. The Embo Journal. 16: 3219-32. PMID 9214638 DOI: 10.1093/Emboj/16.11.3219 |
0.467 |
|
1996 |
Stone EM, Pillus L. Activation of an MAP kinase cascade leads to Sir3p hyperphosphorylation and strengthens transcriptional silencing. The Journal of Cell Biology. 135: 571-83. PMID 8909534 DOI: 10.1083/Jcb.135.3.571 |
0.493 |
|
1996 |
Reifsnyder C, Lowell J, Clarke A, Pillus L. Yeast SAS silencing genes and human genes associated with AML and HIV-1 Tat interactions are homologous with acetyltransferases. Nature Genetics. 14: 42-9. PMID 8782818 DOI: 10.1038/Ng0996-42 |
0.493 |
|
1995 |
Brachmann CB, Sherman JM, Devine SE, Cameron EE, Pillus L, Boeke JD. The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability. Genes & Development. 9: 2888-902. PMID 7498786 DOI: 10.1101/Gad.9.23.2888 |
0.509 |
|
1994 |
Rivier DH, Pillus L. Silencing speaks up. Cell. 76: 963-6. PMID 8137430 DOI: 10.1016/0092-8674(94)90373-5 |
0.503 |
|
1993 |
Palladino F, Laroche T, Gilson E, Axelrod A, Pillus L, Gasser SM. SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres Cell. 75: 543-555. PMID 8221893 DOI: 10.1016/0092-8674(93)90388-7 |
0.454 |
|
1993 |
Palladino F, Laroche T, Gilson E, Pillus L, Gasser SM. The positioning of yeast telomeres depends on SIR3, SIR4, and the integrity of the nuclear membrane Cold Spring Harbor Symposia On Quantitative Biology. 58: 733-746. PMID 7956091 DOI: 10.1101/Sqb.1993.058.01.081 |
0.37 |
|
1992 |
Pillus L. An acquired state: epigenetic mechanisms in transcription. Current Opinion in Cell Biology. 4: 453-8. PMID 1497916 DOI: 10.1016/0955-0674(92)90011-Z |
0.493 |
|
1991 |
Pillus L. Any which way but loose - determining a transcription state in yeast Bioessays. 13: 303-304. DOI: 10.1002/Bies.950130608 |
0.389 |
|
1990 |
Pillus L, Rine J. Epigenetic inheritance of transcriptional states in S. cerevisiae. Cell. 59: 637-47. PMID 2684414 DOI: 10.1016/0092-8674(89)90009-3 |
0.393 |
|
1986 |
Pillus L, Solomon F. Components of microtubular structures in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 83: 2468-72. PMID 3517870 DOI: 10.1073/Pnas.83.8.2468 |
0.341 |
|
1986 |
Schatz PJ, Pillus L, Grisafi P, Solomon F, Botstein D. Two functional alpha-tubulin genes of the yeast Saccharomyces cerevisiae encode divergent proteins. Molecular and Cellular Biology. 6: 3711-21. PMID 3025610 DOI: 10.1128/Mcb.6.11.3711 |
0.345 |
|
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