| Year |
Citation |
Score |
| 2024 |
Richter WF, Taatjes DJ. Changing structures, changing paradigms: NELF helps regulate paused or elongating RNA polymerase II. Molecular Cell. 84: 1180-1182. PMID 38579674 DOI: 10.1016/j.molcel.2024.03.008 |
0.443 |
|
| 2024 |
Jones T, Sigauke RF, Sanford L, Taatjes DJ, Allen MA, Dowell RD. A transcription factor (TF) inference method that broadly measures TF activity and identifies mechanistically distinct TF networks. Biorxiv : the Preprint Server For Biology. PMID 38559193 DOI: 10.1101/2024.03.15.585303 |
0.395 |
|
| 2023 |
Cozzolino K, Sanford L, Hunter S, Molison K, Erickson B, Jones T, Ajit D, Galbraith MD, Espinosa JM, Bentley DL, Allen MA, Dowell RD, Taatjes DJ. Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome. Biorxiv : the Preprint Server For Biology. PMID 37461585 DOI: 10.1101/2023.07.05.547813 |
0.31 |
|
| 2022 |
Nayak S, Taatjes DJ. SnapShot: Mediator complex structure. Cell. 185: 3458-3458.e1. PMID 36055203 DOI: 10.1016/j.cell.2022.07.011 |
0.432 |
|
| 2022 |
Bassett J, Rimel JK, Basu S, Basnet P, Luo J, Engel KL, Nagel M, Woyciehowsky A, Ebmeier CC, Kaplan CD, Taatjes DJ, Ranish JA. Systematic mutagenesis of TFIIH subunit p52/Tfb2 identifies residues required for XPB/Ssl2 subunit function and genetic interactions with TFB6. The Journal of Biological Chemistry. 102433. PMID 36041630 DOI: 10.1016/j.jbc.2022.102433 |
0.778 |
|
| 2022 |
Clopper KC, Taatjes DJ. Chemical inhibitors of transcription-associated kinases. Current Opinion in Chemical Biology. 70: 102186. PMID 35926294 DOI: 10.1016/j.cbpa.2022.102186 |
0.405 |
|
| 2022 |
Richter WF, Nayak S, Iwasa J, Taatjes DJ. The Mediator complex as a master regulator of transcription by RNA polymerase II. Nature Reviews. Molecular Cell Biology. PMID 35725906 DOI: 10.1038/s41580-022-00498-3 |
0.531 |
|
| 2022 |
Allen BL, Quach K, Jones T, Levandowski CB, Ebmeier CC, Rubin JD, Read T, Dowell RD, Schepartz A, Taatjes DJ. Suppression of p53 response by targeting p53-Mediator binding with a stapled peptide. Cell Reports. 39: 110630. PMID 35385747 DOI: 10.1016/j.celrep.2022.110630 |
0.723 |
|
| 2022 |
Luyties O, Taatjes DJ. The Mediator kinase module: an interface between cell signaling and transcription. Trends in Biochemical Sciences. 47: 314-327. PMID 35193797 DOI: 10.1016/j.tibs.2022.01.002 |
0.568 |
|
| 2021 |
Palacio M, Taatjes DJ. Merging Established Mechanisms with New Insights: Condensates, Hubs, and the Regulation of RNA Polymerase II Transcription. Journal of Molecular Biology. 167216. PMID 34474085 DOI: 10.1016/j.jmb.2021.167216 |
0.511 |
|
| 2021 |
Levandowski CB, Jones T, Gruca M, Ramamoorthy S, Dowell RD, Taatjes DJ. The Δ40p53 isoform inhibits p53-dependent eRNA transcription and enables regulation by signal-specific transcription factors during p53 activation. Plos Biology. 19: e3001364. PMID 34351910 DOI: 10.1371/journal.pbio.3001364 |
0.408 |
|
| 2021 |
Schier AC, Taatjes DJ. Everything at once: cryo-EM yields remarkable insights into human RNA polymerase II transcription. Nature Structural & Molecular Biology. 28: 540-543. PMID 34131334 DOI: 10.1038/s41594-021-00613-6 |
0.414 |
|
| 2021 |
Rubin JD, Stanley JT, Sigauke RF, Levandowski CB, Maas ZL, Westfall J, Taatjes DJ, Dowell RD. Transcription factor enrichment analysis (TFEA) quantifies the activity of multiple transcription factors from a single experiment. Communications Biology. 4: 661. PMID 34079046 DOI: 10.1038/s42003-021-02153-7 |
0.378 |
|
| 2021 |
Taatjes DJ. RNA Polymerase II Transcription. Journal of Molecular Biology. 167037. PMID 33957145 DOI: 10.1016/j.jmb.2021.167037 |
0.408 |
|
| 2021 |
Tomko EJ, Luyties O, Rimel JK, Tsai CL, Fuss JO, Fishburn J, Hahn S, Tsutakawa SE, Taatjes DJ, Galburt EA. The role of XPB/Ssl2 dsDNA translocation processivity in transcription-start-site scanning. Journal of Molecular Biology. 166813. PMID 33453189 DOI: 10.1016/j.jmb.2021.166813 |
0.457 |
|
| 2020 |
Rimel JK, Poss ZC, Erickson B, Maas ZL, Ebmeier CC, Johnson JL, Decker TM, Yaron TM, Bradley MJ, Hamman KB, Hu S, Malojcic G, Marineau JJ, White PW, Brault M, ... ... Taatjes DJ, et al. Selective inhibition of CDK7 reveals high-confidence targets and new models for TFIIH function in transcription. Genes & Development. PMID 33060135 DOI: 10.1101/gad.341545.120 |
0.771 |
|
| 2020 |
Schier AC, Taatjes DJ. Structure and mechanism of the RNA polymerase II transcription machinery. Genes & Development. 34: 465-488. PMID 32238450 DOI: 10.1101/Gad.335679.119 |
0.589 |
|
| 2020 |
Fant CB, Levandowski CB, Gupta K, Maas ZL, Moir J, Rubin JD, Sawyer A, Esbin MN, Rimel JK, Luyties O, Marr MT, Berger I, Dowell RD, Taatjes DJ. TFIID Enables RNA Polymerase II Promoter-Proximal Pausing. Molecular Cell. PMID 32229306 DOI: 10.1016/J.Molcel.2020.03.008 |
0.586 |
|
| 2019 |
Zamudio AV, Dall'Agnese A, Henninger JE, Manteiga JC, Afeyan LK, Hannett NM, Coffey EL, Li CH, Oksuz O, Sabari BR, Boija A, Klein IA, Hawken SW, Spille JH, Decker TM, ... ... Taatjes DJ, et al. Mediator Condensates Localize Signaling Factors to Key Cell Identity Genes. Molecular Cell. PMID 31563432 DOI: 10.1016/J.Molcel.2019.08.016 |
0.382 |
|
| 2019 |
Steinparzer I, Sedlyarov V, Rubin JD, Eislmayr K, Galbraith MD, Levandowski CB, Vcelkova T, Sneezum L, Wascher F, Amman F, Kleinova R, Bender H, Andrysik Z, Espinosa JM, Superti-Furga G, ... ... Taatjes DJ, et al. Transcriptional Responses to IFN-γ Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions. Molecular Cell. PMID 31495563 DOI: 10.1016/J.Molcel.2019.07.034 |
0.516 |
|
| 2019 |
Guo YE, Manteiga JC, Henninger JE, Sabari BR, Dall'Agnese A, Hannett NM, Spille JH, Afeyan LK, Zamudio AV, Shrinivas K, Abraham BJ, Boija A, Decker TM, Rimel JK, Fant CB, ... ... Taatjes DJ, et al. Pol II phosphorylation regulates a switch between transcriptional and splicing condensates. Nature. PMID 31391587 DOI: 10.1038/S41586-019-1464-0 |
0.579 |
|
| 2019 |
Guard SE, Poss ZC, Ebmeier CC, Pagratis M, Simpson H, Taatjes DJ, Old WM. The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair. Scientific Reports. 9: 6539. PMID 31024071 DOI: 10.1038/S41598-019-42990-5 |
0.725 |
|
| 2018 |
Fant CB, Taatjes DJ. Regulatory functions of the Mediator kinases CDK8 and CDK19. Transcription. 1-15. PMID 30585107 DOI: 10.1080/21541264.2018.1556915 |
0.469 |
|
| 2018 |
Boija A, Klein IA, Sabari BR, Dall'Agnese A, Coffey EL, Zamudio AV, Li CH, Shrinivas K, Manteiga JC, Hannett NM, Abraham BJ, Afeyan LK, Guo YE, Rimel JK, Fant CB, ... ... Taatjes DJ, et al. Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains. Cell. PMID 30449618 DOI: 10.1016/J.Cell.2018.10.042 |
0.414 |
|
| 2018 |
Goodrich J, Taatjes D. Transcription regulation enters a new phase. Nature. 558: 197-198. PMID 29895907 DOI: 10.1038/D41586-018-05244-4 |
0.432 |
|
| 2018 |
Rimel JK, Taatjes DJ. The essential and multifunctional TFIIH complex. Protein Science : a Publication of the Protein Society. PMID 29664212 DOI: 10.1002/Pro.3424 |
0.563 |
|
| 2017 |
Taatjes DJ. The Continuing SAGA of TFIID and RNA Polymerase II Transcription. Molecular Cell. 68: 1-2. PMID 28985500 DOI: 10.1016/J.Molcel.2017.09.028 |
0.438 |
|
| 2017 |
Harper TM, Taatjes DJ. The complex structure and function of Mediator. The Journal of Biological Chemistry. PMID 28912271 DOI: 10.1074/Jbc.R117.794438 |
0.593 |
|
| 2017 |
Ebmeier CC, Erickson B, Allen BL, Allen MA, Kim H, Fong N, Jacobsen JR, Liang K, Shilatifard A, Dowell RD, Old WM, Bentley DL, Taatjes DJ. Human TFIIH Kinase CDK7 Regulates Transcription-Associated Chromatin Modifications. Cell Reports. 20: 1173-1186. PMID 28768201 DOI: 10.1016/J.Celrep.2017.07.021 |
0.808 |
|
| 2017 |
Taatjes DJ. Transcription factor-Mediator interfaces: Multiple and multi-valent. Journal of Molecular Biology. PMID 28716626 DOI: 10.1016/J.Jmb.2017.07.006 |
0.4 |
|
| 2017 |
Audetat KA, Galbraith MD, Odell AT, Lee T, Pandey A, Espinosa JM, Dowell RD, Taatjes DJ. A kinase-independent role for CDK19 in p53 response. Molecular and Cellular Biology. PMID 28416637 DOI: 10.1128/Mcb.00626-16 |
0.512 |
|
| 2017 |
Alhadid Y, Chung S, Lerner E, Taatjes DJ, Borukhov S, Weiss S. Studying transcription initiation by RNA polymerase with diffusion-based single-molecule fluorescence. Protein Science : a Publication of the Protein Society. PMID 28370550 DOI: 10.1002/Pro.3160 |
0.454 |
|
| 2017 |
Tan Z, Guan X, Chaffey P, Ruan Y, Hurd C, Taatjes D. Chemical Synthesis of the Multiply Phosphorylated and Biotinylated N-Terminal Transactivation Domain of Human p53 (p53TAD) Synlett. 28: 1917-1922. DOI: 10.1055/S-0036-1590834 |
0.388 |
|
| 2016 |
Lerner E, Chung S, Allen BL, Wang S, Lee J, Lu SW, Grimaud LW, Ingargiola A, Michalet X, Alhadid Y, Borukhov S, Strick TR, Taatjes DJ, Weiss S. Backtracked and paused transcription initiation intermediate of Escherichia coli RNA polymerase. Proceedings of the National Academy of Sciences of the United States of America. PMID 27729537 DOI: 10.1073/Pnas.1605038113 |
0.462 |
|
| 2016 |
Passmore LA, Taatjes DJ. Macromolecular Complexes in Transcription and Co-transcriptional RNA Processing. Journal of Molecular Biology. PMID 27155574 DOI: 10.1016/J.Jmb.2016.05.001 |
0.481 |
|
| 2016 |
Poss ZC, Ebmeier CC, Odell AT, Tangpeerachaikul A, Lee T, Pelish HE, Shair MD, Dowell RD, Old WM, Taatjes DJ. Identification of Mediator Kinase Substrates in Human Cells using Cortistatin A and Quantitative Phosphoproteomics. Cell Reports. PMID 27050516 DOI: 10.1016/J.Celrep.2016.03.030 |
0.763 |
|
| 2016 |
Alhadid YK, Allen BL, Chung S, Taatjes DJ, Weiss S. Single-Molecule Assay Development for Studying Human RNA Polymerase II Promoter-Proximal Pausing Biophysical Journal. 110: 639a. DOI: 10.1016/J.Bpj.2015.11.3421 |
0.601 |
|
| 2016 |
Lerner E, Chung S, Allen B, Shuang W, Jookyung LJ, Winson Shijia L, Wilson Logan G, Ingargiola A, Alhadid Y, Borukhov S, Strick T, Taatjes DJ, Weiss S. Pausing in Escherichia coli Transcription Initiation Biophysical Journal. 110: 231a. DOI: 10.1016/J.Bpj.2015.11.1273 |
0.453 |
|
| 2015 |
Rubin JD, Taatjes DJ. Molecular biology: Mediating transcription and RNA export. Nature. 526: 199-200. PMID 26450052 DOI: 10.1038/526199A |
0.494 |
|
| 2015 |
Pelish HE, Liau BB, Nitulescu II, Tangpeerachaikul A, Poss ZC, Da Silva DH, Caruso BT, Arefolov A, Fadeyi O, Christie AL, Du K, Banka D, Schneider EV, Jestel A, Zou G, ... ... Taatjes DJ, et al. Mediator kinase inhibition further activates super-enhancer-associated genes in AML. Nature. 526: 273-6. PMID 26416749 DOI: 10.1038/Nature14904 |
0.752 |
|
| 2015 |
Luo J, Cimermancic P, Viswanath S, Ebmeier CC, Kim B, Dehecq M, Raman V, Greenberg CH, Pellarin R, Sali A, Taatjes DJ, Hahn S, Ranish J. Architecture of the Human and Yeast General Transcription and DNA Repair Factor TFIIH. Molecular Cell. 59: 794-806. PMID 26340423 DOI: 10.1016/J.Molcel.2015.07.016 |
0.742 |
|
| 2015 |
Fant CB, Taatjes DJ. All in the family: a portrait of a nuclear receptor co-activator complex. Molecular Cell. 57: 952-4. PMID 25794613 DOI: 10.1016/J.Molcel.2015.03.001 |
0.324 |
|
| 2015 |
Allen BL, Taatjes DJ. The Mediator complex: a central integrator of transcription. Nature Reviews. Molecular Cell Biology. 16: 155-66. PMID 25693131 DOI: 10.1038/Nrm3951 |
0.606 |
|
| 2014 |
Bunch H, Zheng X, Burkholder A, Dillon ST, Motola S, Birrane G, Ebmeier CC, Levine S, Fargo D, Hu G, Taatjes DJ, Calderwood SK. TRIM28 regulates RNA polymerase II promoter-proximal pausing and pause release. Nature Structural & Molecular Biology. 21: 876-83. PMID 25173174 DOI: 10.1038/Nsmb.2878 |
0.792 |
|
| 2014 |
Sennett NC, Taatjes DJ. Mediator redefines itself. Cell Research. 24: 775-6. PMID 24913192 DOI: 10.1038/Cr.2014.76 |
0.491 |
|
| 2013 |
Phillips AJ, Taatjes DJ. Small molecule probes to target the human Mediator complex. Israel Journal of Chemistry. 53: 588-595. PMID 25705053 DOI: 10.1002/Ijch.201300039 |
0.516 |
|
| 2013 |
Poss ZC, Ebmeier CC, Taatjes DJ. The Mediator complex and transcription regulation. Critical Reviews in Biochemistry and Molecular Biology. 48: 575-608. PMID 24088064 DOI: 10.3109/10409238.2013.840259 |
0.809 |
|
| 2013 |
Lin SC, Karoly ED, Taatjes DJ. The human ΔNp53 isoform triggers metabolic and gene expression changes that activate mTOR and alter mitochondrial function. Aging Cell. 12: 863-72. PMID 23734707 DOI: 10.1111/Acel.12108 |
0.375 |
|
| 2013 |
He Y, Fang J, Taatjes DJ, Nogales E. Structural visualization of key steps in human transcription initiation. Nature. 495: 481-6. PMID 23446344 DOI: 10.1038/Nature11991 |
0.571 |
|
| 2013 |
Lai F, Orom UA, Cesaroni M, Beringer M, Taatjes DJ, Blobel GA, Shiekhattar R. Activating RNAs associate with Mediator to enhance chromatin architecture and transcription. Nature. 494: 497-501. PMID 23417068 DOI: 10.1038/Nature11884 |
0.579 |
|
| 2013 |
Bancerek J, Poss ZC, Steinparzer I, Sedlyarov V, Pfaffenwimmer T, Mikulic I, Dölken L, Strobl B, Müller M, Taatjes DJ, Kovarik P. CDK8 kinase phosphorylates transcription factor STAT1 to selectively regulate the interferon response. Immunity. 38: 250-62. PMID 23352233 DOI: 10.1016/J.Immuni.2012.10.017 |
0.522 |
|
| 2013 |
Davis MA, Larimore EA, Fissel BM, Swanger J, Taatjes DJ, Clurman BE. The SCF-Fbw7 ubiquitin ligase degrades MED13 and MED13L and regulates CDK8 module association with Mediator. Genes & Development. 27: 151-6. PMID 23322298 DOI: 10.1101/Gad.207720.112 |
0.525 |
|
| 2012 |
Schwartz JC, Ebmeier CC, Podell ER, Heimiller J, Taatjes DJ, Cech TR. FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2. Genes & Development. 26: 2690-5. PMID 23249733 DOI: 10.1101/Gad.204602.112 |
0.767 |
|
| 2012 |
Bernecky C, Taatjes DJ. Activator-mediator binding stabilizes RNA polymerase II orientation within the human mediator-RNA polymerase II-TFIIF assembly. Journal of Molecular Biology. 417: 387-94. PMID 22343046 DOI: 10.1016/J.Jmb.2012.02.014 |
0.833 |
|
| 2011 |
Taylor DJ, Podell ER, Taatjes DJ, Cech TR. Multiple POT1-TPP1 proteins coat and compact long telomeric single-stranded DNA. Journal of Molecular Biology. 410: 10-7. PMID 21596049 DOI: 10.1016/J.Jmb.2011.04.049 |
0.321 |
|
| 2011 |
Bernecky C, Grob P, Ebmeier CC, Nogales E, Taatjes DJ. Molecular architecture of the human Mediator-RNA polymerase II-TFIIF assembly. Plos Biology. 9: e1000603. PMID 21468301 DOI: 10.1371/Journal.Pbio.1000603 |
0.805 |
|
| 2011 |
Knuesel MT, Taatjes DJ. Mediator and post-recruitment regulation of RNA polymerase II. Transcription. 2: 28-31. PMID 21326907 DOI: 10.4161/trns.2.1.13950 |
0.825 |
|
| 2011 |
Kagey MH, Newman JJ, Bilodeau S, Zhan Y, Orlando DA, Van Berkum NL, Ebmeier CC, Goossens J, Rahl PB, Levine SS, Taatjes DJ, Dekker J, Young RA. Mediator and cohesin connect gene expression and chromatin architecture (Nature (2010) 467 (430-435)) Nature. 472: 247. DOI: 10.1038/Nature09930 |
0.733 |
|
| 2010 |
De Carlo S, Lin SC, Taatjes DJ, Hoenger A. Molecular basis of transcription initiation in Archaea. Transcription. 1: 103-11. PMID 21326901 DOI: 10.4161/trns.1.2.13189 |
0.374 |
|
| 2010 |
Kagey MH, Newman JJ, Bilodeau S, Zhan Y, Orlando DA, van Berkum NL, Ebmeier CC, Goossens J, Rahl PB, Levine SS, Taatjes DJ, Dekker J, Young RA. Mediator and cohesin connect gene expression and chromatin architecture. Nature. 467: 430-5. PMID 20720539 DOI: 10.1038/nature09380 |
0.746 |
|
| 2010 |
Ebmeier CC, Taatjes DJ. Activator-Mediator binding regulates Mediator-cofactor interactions. Proceedings of the National Academy of Sciences of the United States of America. 107: 11283-8. PMID 20534441 DOI: 10.1073/Pnas.0914215107 |
0.758 |
|
| 2010 |
Meyer KD, Lin SC, Bernecky C, Gao Y, Taatjes DJ. p53 activates transcription by directing structural shifts in Mediator. Nature Structural & Molecular Biology. 17: 753-60. PMID 20453859 DOI: 10.1038/Nsmb.1816 |
0.817 |
|
| 2010 |
Taatjes DJ. The human Mediator complex: a versatile, genome-wide regulator of transcription. Trends in Biochemical Sciences. 35: 315-22. PMID 20299225 DOI: 10.1016/J.Tibs.2010.02.004 |
0.555 |
|
| 2010 |
Donner AJ, Ebmeier CC, Taatjes DJ, Espinosa JM. CDK8 is a positive regulator of transcriptional elongation within the serum response network. Nature Structural & Molecular Biology. 17: 194-201. PMID 20098423 DOI: 10.1038/Nsmb.1752 |
0.788 |
|
| 2009 |
Knuesel MT, Meyer KD, Bernecky C, Taatjes DJ. The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function. Genes & Development. 23: 439-51. PMID 19240132 DOI: 10.1101/Gad.1767009 |
0.792 |
|
| 2009 |
Knuesel MT, Meyer KD, Donner AJ, Espinosa JM, Taatjes DJ. The human CDK8 subcomplex is a histone kinase that requires Med12 for activity and can function independently of mediator. Molecular and Cellular Biology. 29: 650-61. PMID 19047373 DOI: 10.1128/Mcb.00993-08 |
0.8 |
|
| 2008 |
Panning B, Taatjes DJ. Transcriptional regulation: it takes a village. Molecular Cell. 31: 622-9. PMID 18775322 DOI: 10.1016/J.Molcel.2008.08.013 |
0.557 |
|
| 2008 |
Meyer KD, Donner AJ, Knuesel MT, York AG, Espinosa JM, Taatjes DJ. Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3. The Embo Journal. 27: 1447-57. PMID 18418385 DOI: 10.1038/Emboj.2008.78 |
0.784 |
|
| 2004 |
Taatjes DJ, Schneider-Poetsch T, Tjian R. Distinct conformational states of nuclear receptor-bound CRSP-Med complexes. Nature Structural & Molecular Biology. 11: 664-71. PMID 15195149 DOI: 10.1038/Nsmb789 |
0.35 |
|
| 2004 |
Taatjes DJ, Tjian R. Structure and function of CRSP/Med2; a promoter-selective transcriptional coactivator complex. Molecular Cell. 14: 675-83. PMID 15175162 DOI: 10.1016/J.Molcel.2004.05.014 |
0.53 |
|
| 2004 |
Taatjes DJ, Marr MT, Tjian R. Regulatory diversity among metazoan co-activator complexes. Nature Reviews. Molecular Cell Biology. 5: 403-10. PMID 15122353 DOI: 10.1038/Nrm1369 |
0.475 |
|
| 2002 |
Näär AM, Taatjes DJ, Zhai W, Nogales E, Tjian R. Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation. Genes & Development. 16: 1339-44. PMID 12050112 DOI: 10.1101/Gad.987602 |
0.564 |
|
| 2002 |
Taatjes DJ, Näär AM, Andel F, Nogales E, Tjian R. Structure, function, and activator-induced conformations of the CRSP coactivator. Science (New York, N.Y.). 295: 1058-62. PMID 11834832 DOI: 10.1126/Science.1065249 |
0.447 |
|
| 1999 |
Poynter ME, Janssen-Heininger YMW, Buder-Hoffmann S, Taatjes DJ, Mossman BT. Measurement of oxidant-induced signal transduction proteins using cell imaging Free Radical Biology and Medicine. 27: 1164-1172. PMID 10641707 DOI: 10.1016/S0891-5849(99)00202-6 |
0.306 |
|
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