| Year |
Citation |
Score |
| 2024 |
Nabeel-Shah S, Pu S, Burns JD, Braunschweig U, Ahmed N, Burke GL, Lee H, Radovani E, Zhong G, Tang H, Marcon E, Zhang Z, Hughes TR, Blencowe BJ, Greenblatt JF. C2H2-zinc-finger transcription factors bind RNA and function in diverse post-transcriptional regulatory processes. Molecular Cell. PMID 39303720 DOI: 10.1016/j.molcel.2024.08.037 |
0.334 |
|
| 2024 |
Li JD, Taipale M, Blencowe BJ. Efficient, specific, and combinatorial control of endogenous exon splicing with dCasRx-RBM25. Molecular Cell. PMID 38917795 DOI: 10.1016/j.molcel.2024.05.028 |
0.33 |
|
| 2023 |
Roth JF, Braunschweig U, Wu M, Li JD, Lin ZY, Larsen B, Weatheritt RJ, Gingras AC, Blencowe BJ. Systematic analysis of alternative exon-dependent interactome remodeling reveals multitasking functions of gene regulatory factors. Molecular Cell. 83: 4222-4238.e10. PMID 38065061 DOI: 10.1016/j.molcel.2023.10.034 |
0.443 |
|
| 2023 |
Ray D, Laverty KU, Jolma A, Nie K, Samson R, Pour SE, Tam CL, von Krosigk N, Nabeel-Shah S, Albu M, Zheng H, Perron G, Lee H, Najafabadi H, Blencowe B, et al. RNA-binding proteins that lack canonical RNA-binding domains are rarely sequence-specific. Scientific Reports. 13: 5238. PMID 37002329 DOI: 10.1038/s41598-023-32245-9 |
0.349 |
|
| 2022 |
Song J, Nabeel-Shah S, Pu S, Lee H, Braunschweig U, Ni Z, Ahmed N, Marcon E, Zhong G, Ray D, Ha KCH, Guo X, Zhang Z, Hughes TR, Blencowe BJ, et al. Regulation of alternative polyadenylation by the C2H2-zinc-finger protein Sp1. Molecular Cell. PMID 35914531 DOI: 10.1016/j.molcel.2022.06.031 |
0.388 |
|
| 2022 |
Han H, Best AJ, Braunschweig U, Mikolajewicz N, Li JD, Roth J, Chowdhury F, Mantica F, Nabeel-Shah S, Parada G, Brown KR, O'Hanlon D, Wei J, Yao Y, Zid AA, ... ... Blencowe BJ, et al. Systematic exploration of dynamic splicing networks reveals conserved multistage regulators of neurogenesis. Molecular Cell. PMID 35914530 DOI: 10.1016/j.molcel.2022.06.036 |
0.646 |
|
| 2022 |
Barutcu AR, Wu M, Braunschweig U, Dyakov BJA, Luo Z, Turner KM, Durbic T, Lin ZY, Weatheritt RJ, Maass PG, Gingras AC, Blencowe BJ. Systematic mapping of nuclear domain-associated transcripts reveals speckles and lamina as hubs of functionally distinct retained introns. Molecular Cell. PMID 35182477 DOI: 10.1016/j.molcel.2021.12.010 |
0.419 |
|
| 2021 |
Dumbović G, Braunschweig U, Langner HK, Smallegan M, Biayna J, Hass EP, Jastrzebska K, Blencowe B, Cech TR, Caruthers MH, Rinn JL. Nuclear compartmentalization of TERT mRNA and TUG1 lncRNA is driven by intron retention. Nature Communications. 12: 3308. PMID 34083519 DOI: 10.1038/s41467-021-23221-w |
0.398 |
|
| 2020 |
Rodrigues DC, Mufteev M, Weatheritt RJ, Djuric U, Ha KCH, Ross PJ, Wei W, Piekna A, Sartori MA, Byres L, Mok RSF, Zaslavsky K, Pasceri P, Diamandis P, Morris Q, ... Blencowe BJ, et al. Shifts in Ribosome Engagement Impact Key Gene Sets in Neurodevelopment and Ubiquitination in Rett Syndrome. Cell Reports. 30: 4179-4196.e11. PMID 32209477 DOI: 10.1016/j.celrep.2020.02.107 |
0.415 |
|
| 2020 |
Gonatopoulos-Pournatzis T, Niibori R, Salter EW, Weatheritt RJ, Tsang B, Farhangmehr S, Liang X, Braunschweig U, Roth J, Zhang S, Henderson T, Sharma E, Quesnel-Vallières M, Permanyer J, Maier S, ... ... Blencowe BJ, et al. Autism-Misregulated eIF4G Microexons Control Synaptic Translation and Higher Order Cognitive Functions. Molecular Cell. PMID 31999954 DOI: 10.1016/J.Molcel.2020.01.006 |
0.597 |
|
| 2019 |
Ule J, Blencowe BJ. Alternative Splicing Regulatory Networks: Functions, Mechanisms, and Evolution. Molecular Cell. 76: 329-345. PMID 31626751 DOI: 10.1016/j.molcel.2019.09.017 |
0.405 |
|
| 2019 |
Capponi S, Stöffler N, Irimia M, Van Schaik FMA, Ondik MM, Biniossek ML, Lehmann L, Mitschke J, Vermunt MW, Creyghton MP, Graybiel AM, Reinheckel T, Schilling O, Blencowe BJ, Crittenden JR, et al. Neuronal-specific microexon splicing of mRNA is directly regulated by SRRM4/nSR100. Rna Biology. 1-13. PMID 31559909 DOI: 10.1080/15476286.2019.1667214 |
0.615 |
|
| 2019 |
Barutcu AR, Blencowe BJ, Rinn JL. Differential contribution of steady-state RNA and active transcription in chromatin organization. Embo Reports. e48068. PMID 31448565 DOI: 10.15252/embr.201948068 |
0.337 |
|
| 2019 |
Andersen RE, Hong SJ, Lim JJ, Cui M, Harpur BA, Hwang E, Delgado RN, Ramos AD, Liu SJ, Blencowe BJ, Lim DA. The Long Noncoding RNA Pnky Is a Trans-acting Regulator of Cortical Development In Vivo. Developmental Cell. 49: 632-642.e7. PMID 31112699 DOI: 10.1016/J.Devcel.2019.04.032 |
0.375 |
|
| 2019 |
Torres-Méndez A, Bonnal S, Marquez Y, Roth J, Iglesias M, Permanyer J, Almudí I, O'Hanlon D, Guitart T, Soller M, Gingras AC, Gebauer F, Rentzsch F, Blencowe BJ, Valcárcel J, et al. A novel protein domain in an ancestral splicing factor drove the evolution of neural microexons. Nature Ecology & Evolution. PMID 30833759 DOI: 10.1038/S41559-019-0813-6 |
0.642 |
|
| 2019 |
Magomedova L, Tiefenbach J, Zilberman E, Le Billan F, Voisin V, Saikali M, Boivin V, Robitaille M, Gueroussov S, Irimia M, Ray D, Patel R, Xu C, Jeyasuria P, Bader GD, ... ... Blencowe BJ, et al. ARGLU1 is a transcriptional coactivator and splicing regulator important for stress hormone signaling and development. Nucleic Acids Research. PMID 30698747 DOI: 10.1093/Nar/Gkz010 |
0.656 |
|
| 2018 |
Gonatopoulos-Pournatzis T, Wu M, Braunschweig U, Roth J, Han H, Best AJ, Raj B, Aregger M, O'Hanlon D, Ellis JD, Calarco JA, Moffat J, Gingras AC, Blencowe BJ. Genome-wide CRISPR-Cas9 Interrogation of Splicing Networks Reveals a Mechanism for Recognition of Autism-Misregulated Neuronal Microexons. Molecular Cell. 72: 510-524.e12. PMID 30388412 DOI: 10.1016/J.Molcel.2018.10.008 |
0.729 |
|
| 2018 |
Sterne-Weiler T, Weatheritt RJ, Best AJ, Ha KCH, Blencowe BJ. Efficient and Accurate Quantitative Profiling of Alternative Splicing Patterns of Any Complexity on a Laptop. Molecular Cell. PMID 30220560 DOI: 10.1016/j.molcel.2018.08.018 |
0.353 |
|
| 2018 |
Parikshak NN, Swarup V, Belgard TG, Irimia M, Ramaswami G, Gandal MJ, Hartl C, Leppa V, de la Torre Ubieta L, Huang J, Lowe JK, Blencowe BJ, Horvath S, Geschwind DH. Author Correction: Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism. Nature. PMID 29995847 DOI: 10.1038/S41586-018-0295-8 |
0.55 |
|
| 2018 |
Ha KCH, Blencowe BJ, Morris Q. QAPA: a new method for the systematic analysis of alternative polyadenylation from RNA-seq data. Genome Biology. 19: 45. PMID 29592814 DOI: 10.1186/s13059-018-1414-4 |
0.32 |
|
| 2017 |
Tapial J, Ha KCH, Sterne-Weiler T, Gohr A, Braunschweig U, Hermoso-Pulido A, Quesnel-Vallières M, Permanyer J, Sodaei R, Marquez Y, Cozzuto L, Wang X, Gómez-Velázquez M, Rayon T, Manzanares M, ... ... Blencowe B, et al. An atlas of alternative splicing profiles and functional associations reveals new regulatory programs and genes that simultaneously express multiple major isoforms. Genome Research. PMID 28855263 DOI: 10.1101/Gr.220962.117 |
0.69 |
|
| 2017 |
Gueroussov S, Weatheritt RJ, O'Hanlon D, Lin ZY, Narula A, Gingras AC, Blencowe BJ. Regulatory Expansion in Mammals of Multivalent hnRNP Assemblies that Globally Control Alternative Splicing. Cell. 170: 324-339.e23. PMID 28709000 DOI: 10.1016/J.Cell.2017.06.037 |
0.46 |
|
| 2017 |
Muñoz MJ, Nieto Moreno N, Giono LE, Cambindo Botto AE, Dujardin G, Bastianello G, Lavore S, Torres-Méndez A, Menck CF, Blencowe BJ, Irimia M, Foiani M, Kornblihtt AR. Major Roles for Pyrimidine Dimers, Nucleotide Excision Repair, and ATR in the Alternative Splicing Response to UV Irradiation. Cell Reports. 18: 2868-2879. PMID 28329680 DOI: 10.1016/J.Celrep.2017.02.066 |
0.532 |
|
| 2017 |
Han H, Braunschweig U, Gonatopoulos-Pournatzis T, Weatheritt RJ, Hirsch CL, Ha KC, Radovani E, Nabeel-Shah S, Sterne-Weiler T, Wang J, O'Hanlon D, Pan Q, Ray D, Zheng H, Vizeacoumar F, ... ... Blencowe BJ, et al. Multilayered Control of Alternative Splicing Regulatory Networks by Transcription Factors. Molecular Cell. 65: 539-553.e7. PMID 28157508 DOI: 10.1016/J.Molcel.2017.01.011 |
0.403 |
|
| 2017 |
Balachandran A, Wong R, Stoilov P, Pan S, Blencowe B, Cheung P, Harrigan PR, Cochrane A. Identification of small molecule modulators of HIV-1 Tat and Rev protein accumulation. Retrovirology. 14: 7. PMID 28122580 DOI: 10.1186/S12977-017-0330-0 |
0.386 |
|
| 2016 |
Quesnel-Vallières M, Dargaei Z, Irimia M, Gonatopoulos-Pournatzis T, Ip JY, Wu M, Sterne-Weiler T, Nakagawa S, Woodin MA, Blencowe BJ, Cordes SP. Misregulation of an Activity-Dependent Splicing Network as a Common Mechanism Underlying Autism Spectrum Disorders. Molecular Cell. 64: 1023-1034. PMID 27984743 DOI: 10.1016/J.Molcel.2016.11.033 |
0.579 |
|
| 2016 |
Parikshak NN, Swarup V, Belgard TG, Irimia M, Ramaswami G, Gandal MJ, Hartl C, Leppa V, Ubieta LT, Huang J, Lowe JK, Blencowe BJ, Horvath S, Geschwind DH. Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism. Nature. PMID 27919067 DOI: 10.1038/Nature20612 |
0.613 |
|
| 2016 |
Weatheritt RJ, Sterne-Weiler T, Blencowe BJ. The ribosome-engaged landscape of alternative splicing. Nature Structural & Molecular Biology. PMID 27820807 DOI: 10.1038/nsmb.3317 |
0.452 |
|
| 2016 |
Tahmasebi S, Jafarnejad SM, Tam IS, Gonatopoulos-Pournatzis T, Matta-Camacho E, Tsukumo Y, Yanagiya A, Li W, Atlasi Y, Caron M, Braunschweig U, Pearl D, Khoutorsky A, Gkogkas CG, Nadon R, ... ... Blencowe BJ, et al. Control of embryonic stem cell self-renewal and differentiation via coordinated alternative splicing and translation of YY2. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791185 DOI: 10.1073/Pnas.1615540113 |
0.343 |
|
| 2016 |
Rodrigues DC, Kim DS, Yang G, Zaslavsky K, Ha KC, Mok RS, Ross PJ, Zhao M, Piekna A, Wei W, Blencowe BJ, Morris Q, Ellis J. MECP2 Is Post-transcriptionally Regulated during Human Neurodevelopment by Combinatorial Action of RNA-Binding Proteins and miRNAs. Cell Reports. 17: 720-734. PMID 27732849 DOI: 10.1016/j.celrep.2016.09.049 |
0.391 |
|
| 2016 |
Solana J, Irimia M, Ayoub S, Orejuela MR, Zywitza V, Jens M, Tapial J, Ray D, Morris Q, Hughes TR, Blencowe BJ, Rajewsky N. Conserved functional antagonism of CELF and MBNL proteins controls stem cell-specific alternative splicing in planarians. Elife. 5. PMID 27502555 DOI: 10.7554/eLife.16797 |
0.598 |
|
| 2016 |
Rodor J, Pan Q, Blencowe BJ, Eyras E, Cáceres JF. The RNA-binding profile of Acinus, a peripheral component of the exon junction complex, reveals its role in splicing regulation. Rna (New York, N.Y.). PMID 27365209 DOI: 10.1261/Rna.057158.116 |
0.468 |
|
| 2016 |
Ennajdaoui H, Howard JM, Sterne-Weiler T, Jahanbani F, Coyne DJ, Uren PJ, Dargyte M, Katzman S, Draper JM, Wallace A, Cazarez O, Burns SC, Qiao M, Hinck L, Smith AD, ... ... Blencowe BJ, et al. IGF2BP3 Modulates the Interaction of Invasion-Associated Transcripts with RISC. Cell Reports. PMID 27210763 DOI: 10.1016/J.Celrep.2016.04.083 |
0.382 |
|
| 2016 |
Sharma E, Sterne-Weiler T, O'Hanlon D, Blencowe BJ. Global Mapping of Human RNA-RNA Interactions. Molecular Cell. PMID 27184080 DOI: 10.1016/j.molcel.2016.04.030 |
0.338 |
|
| 2015 |
Yanling Zhao D, Gish G, Braunschweig U, Li Y, Ni Z, Schmitges FW, Zhong G, Liu K, Li W, Moffat J, Vedadi M, Min J, Pawson TJ, Blencowe BJ, Greenblatt JF. SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Nature. PMID 26700805 DOI: 10.1038/Nature16469 |
0.365 |
|
| 2015 |
Giampietro C, Deflorian G, Gallo S, Di Matteo A, Pradella D, Bonomi S, Belloni E, Nyqvist D, Quaranta V, Confalonieri S, Bertalot G, Orsenigo F, Pisati F, Ferrero E, Biamonti G, ... ... Blencowe BJ, et al. The alternative splicing factor Nova2 regulates vascular development and lumen formation. Nature Communications. 6: 8479. PMID 26446569 DOI: 10.1038/Ncomms9479 |
0.581 |
|
| 2015 |
Gueroussov S, Gonatopoulos-Pournatzis T, Irimia M, Raj B, Lin ZY, Gingras AC, Blencowe BJ. RNA SPLICING. An alternative splicing event amplifies evolutionary differences between vertebrates. Science (New York, N.Y.). 349: 868-73. PMID 26293963 DOI: 10.1126/Science.Aaa8381 |
0.673 |
|
| 2015 |
Raj B, Blencowe BJ. Alternative Splicing in the Mammalian Nervous System: Recent Insights into Mechanisms and Functional Roles. Neuron. 87: 14-27. PMID 26139367 DOI: 10.1016/j.neuron.2015.05.004 |
0.362 |
|
| 2015 |
Quesnel-Vallières M, Irimia M, Cordes SP, Blencowe BJ. Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development. Genes & Development. 29: 746-59. PMID 25838543 DOI: 10.1101/gad.256115.114 |
0.629 |
|
| 2015 |
Gueroussov S, Gonatopoulos-Pournatzis T, Irimia M, Raj B, Lin ZY, Gingras AC, Blencowe BJ. An alternative splicing event amplifies evolutionary differences between vertebrates Science. 349: 868-873. DOI: 10.1126/science.aaa8381 |
0.39 |
|
| 2015 |
Raj B, Blencowe BJ. Alternative Splicing in the Mammalian Nervous System: Recent Insights into Mechanisms and Functional Roles Neuron. 87: 14-27. DOI: 10.1016/j.neuron.2015.05.004 |
0.362 |
|
| 2014 |
Irimia M, Weatheritt RJ, Ellis JD, Parikshak NN, Gonatopoulos-Pournatzis T, Babor M, Quesnel-Vallières M, Tapial J, Raj B, O'Hanlon D, Barrios-Rodiles M, Sternberg MJ, Cordes SP, Roth FP, Wrana JL, ... ... Blencowe BJ, et al. A highly conserved program of neuronal microexons is misregulated in autistic brains. Cell. 159: 1511-23. PMID 25525873 DOI: 10.1016/J.Cell.2014.11.035 |
0.621 |
|
| 2014 |
Braunschweig U, Barbosa-Morais NL, Pan Q, Nachman EN, Alipanahi B, Gonatopoulos-Pournatzis T, Frey B, Irimia M, Blencowe BJ. Widespread intron retention in mammals functionally tunes transcriptomes. Genome Research. 24: 1774-86. PMID 25258385 DOI: 10.1101/Gr.177790.114 |
0.673 |
|
| 2014 |
Raj B, Irimia M, Braunschweig U, Sterne-Weiler T, O'Hanlon D, Lin ZY, Chen GI, Easton LE, Ule J, Gingras AC, Eyras E, Blencowe BJ. A global regulatory mechanism for activating an exon network required for neurogenesis. Molecular Cell. 56: 90-103. PMID 25219497 DOI: 10.1016/J.Molcel.2014.08.011 |
0.64 |
|
| 2014 |
Katsani KR, Irimia M, Karapiperis C, Scouras ZG, Blencowe BJ, Promponas VJ, Ouzounis CA. Functional genomics evidence unearths new moonlighting roles of outer ring coat nucleoporins. Scientific Reports. 4: 4655. PMID 24722254 DOI: 10.1038/srep04655 |
0.636 |
|
| 2013 |
Sebé-Pedrós A, Irimia M, Del Campo J, Parra-Acero H, Russ C, Nusbaum C, Blencowe BJ, Ruiz-Trillo I. Regulated aggregative multicellularity in a close unicellular relative of metazoa. Elife. 2: e01287. PMID 24368732 DOI: 10.7554/Elife.01287 |
0.568 |
|
| 2013 |
Ray D, Kazan H, Cook KB, Weirauch MT, Najafabadi HS, Li X, Gueroussov S, Albu M, Zheng H, Yang A, Na H, Irimia M, Matzat LH, Dale RK, Smith SA, ... ... Blencowe BJ, et al. A compendium of RNA-binding motifs for decoding gene regulation. Nature. 499: 172-7. PMID 23846655 DOI: 10.1038/Nature12311 |
0.659 |
|
| 2013 |
Han H, Irimia M, Ross PJ, Sung HK, Alipanahi B, David L, Golipour A, Gabut M, Michael IP, Nachman EN, Wang E, Trcka D, Thompson T, O'Hanlon D, Slobodeniuc V, ... ... Blencowe BJ, et al. MBNL proteins repress ES-cell-specific alternative splicing and reprogramming. Nature. 498: 241-5. PMID 23739326 DOI: 10.1038/Nature12270 |
0.745 |
|
| 2013 |
Colak R, Kim T, Michaut M, Sun M, Irimia M, Bellay J, Myers CL, Blencowe BJ, Kim PM. Distinct types of disorder in the human proteome: functional implications for alternative splicing. Plos Computational Biology. 9: e1003030. PMID 23633940 DOI: 10.1371/Journal.Pcbi.1003030 |
0.582 |
|
| 2013 |
Braunschweig U, Gueroussov S, Plocik AM, Graveley BR, Blencowe BJ. Dynamic integration of splicing within gene regulatory pathways. Cell. 152: 1252-69. PMID 23498935 DOI: 10.1016/J.Cell.2013.02.034 |
0.417 |
|
| 2012 |
Barbosa-Morais NL, Irimia M, Pan Q, Xiong HY, Gueroussov S, Lee LJ, Slobodeniuc V, Kutter C, Watt S, Colak R, Kim T, Misquitta-Ali CM, Wilson MD, Kim PM, Odom DT, ... ... Blencowe BJ, et al. The evolutionary landscape of alternative splicing in vertebrate species. Science (New York, N.Y.). 338: 1587-93. PMID 23258890 DOI: 10.1126/Science.1230612 |
0.584 |
|
| 2012 |
Khare T, Pai S, Koncevicius K, Pal M, Kriukiene E, Liutkeviciute Z, Irimia M, Jia P, Ptak C, Xia M, Tice R, Tochigi M, Moréra S, Nazarians A, Belsham D, ... ... Blencowe BJ, et al. 5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary. Nature Structural & Molecular Biology. 19: 1037-43. PMID 22961382 DOI: 10.1038/Nsmb.2372 |
0.591 |
|
| 2012 |
Blencowe BJ. An exon-centric perspective. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 90: 603-12. PMID 22779775 DOI: 10.1139/o2012-019 |
0.379 |
|
| 2012 |
Ellis JD, Barrios-Rodiles M, Colak R, Irimia M, Kim T, Calarco JA, Wang X, Pan Q, O'Hanlon D, Kim PM, Wrana JL, Blencowe BJ. Tissue-specific alternative splicing remodels protein-protein interaction networks. Molecular Cell. 46: 884-92. PMID 22749401 DOI: 10.1016/J.Molcel.2012.05.037 |
0.775 |
|
| 2012 |
Labbé RM, Irimia M, Currie KW, Lin A, Zhu SJ, Brown DD, Ross EJ, Voisin V, Bader GD, Blencowe BJ, Pearson BJ. A comparative transcriptomic analysis reveals conserved features of stem cell pluripotency in planarians and mammals. Stem Cells (Dayton, Ohio). 30: 1734-45. PMID 22696458 DOI: 10.1002/Stem.1144 |
0.55 |
|
| 2012 |
Irimia M, Blencowe BJ. Alternative splicing: decoding an expansive regulatory layer. Current Opinion in Cell Biology. 24: 323-32. PMID 22465326 DOI: 10.1016/j.ceb.2012.03.005 |
0.673 |
|
| 2012 |
Martinez NM, Pan Q, Cole BS, Yarosh CA, Babcock GA, Heyd F, Zhu W, Ajith S, Blencowe BJ, Lynch KW. Alternative splicing networks regulated by signaling in human T cells. Rna (New York, N.Y.). 18: 1029-40. PMID 22454538 DOI: 10.1261/rna.032243.112 |
0.301 |
|
| 2011 |
Lahiry P, Lee LJ, Frey BJ, Rupar CA, Siu VM, Blencowe BJ, Hegele RA. Transcriptional profiling of endocrine cerebro-osteodysplasia using microarray and next-generation sequencing. Plos One. 6: e25400. PMID 21980446 DOI: 10.1371/Journal.Pone.0025400 |
0.38 |
|
| 2011 |
Gabut M, Samavarchi-Tehrani P, Wang X, Slobodeniuc V, O'Hanlon D, Sung HK, Alvarez M, Talukder S, Pan Q, Mazzoni EO, Nedelec S, Wichterle H, Woltjen K, Hughes TR, Zandstra PW, ... ... Blencowe BJ, et al. An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming. Cell. 147: 132-46. PMID 21924763 DOI: 10.1016/J.Cell.2011.08.023 |
0.323 |
|
| 2011 |
Raj B, O'Hanlon D, Vessey JP, Pan Q, Ray D, Buckley NJ, Miller FD, Blencowe BJ. Cross-regulation between an alternative splicing activator and a transcription repressor controls neurogenesis. Molecular Cell. 43: 843-50. PMID 21884984 DOI: 10.1016/j.molcel.2011.08.014 |
0.38 |
|
| 2011 |
Calarco JA, Zhen M, Blencowe BJ. Networking in a global world: establishing functional connections between neural splicing regulators and their target transcripts. Rna (New York, N.Y.). 17: 775-91. PMID 21415141 DOI: 10.1261/Rna.2603911 |
0.804 |
|
| 2011 |
Saltzman AL, Pan Q, Blencowe BJ. Regulation of alternative splicing by the core spliceosomal machinery. Genes & Development. 25: 373-84. PMID 21325135 DOI: 10.1101/Gad.2004811 |
0.823 |
|
| 2011 |
Ramani AK, Calarco JA, Pan Q, Mavandadi S, Wang Y, Nelson AC, Lee LJ, Morris Q, Blencowe BJ, Zhen M, Fraser AG. Genome-wide analysis of alternative splicing in Caenorhabditis elegans. Genome Research. 21: 342-8. PMID 21177968 DOI: 10.1101/Gr.114645.110 |
0.773 |
|
| 2011 |
Ip JY, Schmidt D, Pan Q, Ramani AK, Fraser AG, Odom DT, Blencowe BJ. Global impact of RNA polymerase II elongation inhibition on alternative splicing regulation. Genome Research. 21: 390-401. PMID 21163941 DOI: 10.1101/Gr.111070.110 |
0.379 |
|
| 2010 |
Tripathi V, Ellis JD, Shen Z, Song DY, Pan Q, Watt AT, Freier SM, Bennett CF, Sharma A, Bubulya PA, Blencowe BJ, Prasanth SG, Prasanth KV. The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation. Molecular Cell. 39: 925-38. PMID 20797886 DOI: 10.1016/j.molcel.2010.08.011 |
0.451 |
|
| 2010 |
McIlwain DR, Pan Q, Reilly PT, Elia AJ, McCracken S, Wakeham AC, Itie-Youten A, Blencowe BJ, Mak TW. Smg1 is required for embryogenesis and regulates diverse genes via alternative splicing coupled to nonsense-mediated mRNA decay. Proceedings of the National Academy of Sciences of the United States of America. 107: 12186-91. PMID 20566848 DOI: 10.1073/pnas.1007336107 |
0.443 |
|
| 2010 |
van Bakel H, Nislow C, Blencowe BJ, Hughes TR. Most "dark matter" transcripts are associated with known genes. Plos Biology. 8: e1000371. PMID 20502517 DOI: 10.1371/Journal.Pbio.1000371 |
0.415 |
|
| 2010 |
Barash Y, Calarco JA, Gao W, Pan Q, Wang X, Shai O, Blencowe BJ, Frey BJ. Deciphering the splicing code. Nature. 465: 53-9. PMID 20445623 DOI: 10.1038/Nature09000 |
0.731 |
|
| 2010 |
Luco RF, Pan Q, Tominaga K, Blencowe BJ, Pereira-Smith OM, Misteli T. Regulation of alternative splicing by histone modifications. Science (New York, N.Y.). 327: 996-1000. PMID 20133523 DOI: 10.1126/Science.1184208 |
0.315 |
|
| 2009 |
Khanna M, Van Bakel H, Tang X, Calarco JA, Babak T, Guo G, Emili A, Greenblatt JF, Hughes TR, Krogan NJ, Blencowe BJ. A systematic characterization of Cwc21, the yeast ortholog of the human spliceosomal protein SRm300. Rna (New York, N.Y.). 15: 2174-85. PMID 19789211 DOI: 10.1261/Rna.1790509 |
0.793 |
|
| 2009 |
Kornblihtt AR, Schor IE, Allo M, Blencowe BJ. When chromatin meets splicing. Nature Structural & Molecular Biology. 16: 902-3. PMID 19739285 DOI: 10.1038/nsmb0909-902 |
0.354 |
|
| 2009 |
Calarco JA, Superina S, O'Hanlon D, Gabut M, Raj B, Pan Q, Skalska U, Clarke L, Gelinas D, van der Kooy D, Zhen M, Ciruna B, Blencowe BJ. Regulation of vertebrate nervous system alternative splicing and development by an SR-related protein. Cell. 138: 898-910. PMID 19737518 DOI: 10.1016/J.Cell.2009.06.012 |
0.786 |
|
| 2009 |
Ray D, Kazan H, Chan ET, Peña Castillo L, Chaudhry S, Talukder S, Blencowe BJ, Morris Q, Hughes TR. Rapid and systematic analysis of the RNA recognition specificities of RNA-binding proteins. Nature Biotechnology. 27: 667-70. PMID 19561594 DOI: 10.1038/Nbt.1550 |
0.303 |
|
| 2009 |
Blencowe B, Brenner S, Hughes T, Morris Q. Post-transcriptional gene regulation: RNA-protein interactions, RNA processing, mRNA stability and localization. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 545-8. PMID 19209730 |
0.382 |
|
| 2008 |
Pan Q, Shai O, Lee LJ, Frey BJ, Blencowe BJ. Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing. Nature Genetics. 40: 1413-5. PMID 18978789 DOI: 10.1038/Ng.259 |
0.375 |
|
| 2008 |
Aznarez I, Barash Y, Shai O, He D, Zielenski J, Tsui LC, Parkinson J, Frey BJ, Rommens JM, Blencowe BJ. A systematic analysis of intronic sequences downstream of 5' splice sites reveals a widespread role for U-rich motifs and TIA1/TIAL1 proteins in alternative splicing regulation. Genome Research. 18: 1247-58. PMID 18456862 DOI: 10.1101/Gr.073155.107 |
0.401 |
|
| 2008 |
Saltzman AL, Kim YK, Pan Q, Fagnani MM, Maquat LE, Blencowe BJ. Regulation of multiple core spliceosomal proteins by alternative splicing-coupled nonsense-mediated mRNA decay. Molecular and Cellular Biology. 28: 4320-30. PMID 18443041 DOI: 10.1128/Mcb.00361-08 |
0.812 |
|
| 2008 |
Gabut M, Chaudhry S, Blencowe BJ. SnapShot: The splicing regulatory machinery. Cell. 133: 192.e1. PMID 18394998 DOI: 10.1016/j.cell.2008.03.010 |
0.397 |
|
| 2008 |
Misquitta-Ali C, Cheng E, Shai O, Liu N, Pan Q, Lee L, O'Hanlon D, McGlade J, Tsao M, Blencowe B. Abstract B67: Using alternative splicing microarrays to identify potential biomarkers in lung cancer Cancer Prevention Research. 1. DOI: 10.1158/1940-6207.Prev-08-B67 |
0.444 |
|
| 2007 |
Calarco JA, Saltzman AL, Ip JY, Blencowe BJ. Technologies for the global discovery and analysis of alternative splicing. Advances in Experimental Medicine and Biology. 623: 64-84. PMID 18380341 DOI: 10.1007/978-0-387-77374-2_5 |
0.791 |
|
| 2007 |
Calarco JA, Xing Y, Cáceres M, Calarco JP, Xiao X, Pan Q, Lee C, Preuss TM, Blencowe BJ. Global analysis of alternative splicing differences between humans and chimpanzees. Genes & Development. 21: 2963-75. PMID 17978102 DOI: 10.1101/Gad.1606907 |
0.724 |
|
| 2007 |
Fagnani M, Barash Y, Ip JY, Misquitta C, Pan Q, Saltzman AL, Shai O, Lee L, Rozenhek A, Mohammad N, Willaime-Morawek S, Babak T, Zhang W, Hughes TR, van der Kooy D, ... ... Blencowe BJ, et al. Functional coordination of alternative splicing in the mammalian central nervous system. Genome Biology. 8: R108. PMID 17565696 DOI: 10.1186/Gb-2007-8-6-R108 |
0.793 |
|
| 2007 |
Fortes P, Longman D, McCracken S, Ip JY, Poot R, Mattaj IW, Cáceres JF, Blencowe BJ. Identification and characterization of RED120: a conserved PWI domain protein with links to splicing and 3'-end formation. Febs Letters. 581: 3087-97. PMID 17560998 DOI: 10.1016/J.Febslet.2007.05.066 |
0.45 |
|
| 2007 |
Blencowe BJ, Khanna M. Molecular biology: RNA in control. Nature. 447: 391-3. PMID 17522667 DOI: 10.1038/447391A |
0.7 |
|
| 2006 |
Ule J, Stefani G, Mele A, Ruggiu M, Wang X, Taneri B, Gaasterland T, Blencowe BJ, Darnell RB. An RNA map predicting Nova-dependent splicing regulation. Nature. 444: 580-6. PMID 17065982 DOI: 10.1038/Nature05304 |
0.327 |
|
| 2006 |
Hughes TR, Hiley SL, Saltzman AL, Babak T, Blencowe BJ. Microarray analysis of RNA processing and modification. Methods in Enzymology. 410: 300-16. PMID 16938557 DOI: 10.1016/S0076-6879(06)10014-2 |
0.769 |
|
| 2006 |
Blencowe BJ. Alternative splicing: new insights from global analyses. Cell. 126: 37-47. PMID 16839875 DOI: 10.1016/j.cell.2006.06.023 |
0.368 |
|
| 2006 |
Pan Q, Saltzman AL, Kim YK, Misquitta C, Shai O, Maquat LE, Frey BJ, Blencowe BJ. Quantitative microarray profiling provides evidence against widespread coupling of alternative splicing with nonsense-mediated mRNA decay to control gene expression. Genes & Development. 20: 153-8. PMID 16418482 DOI: 10.1101/Gad.1382806 |
0.799 |
|
| 2006 |
Shai O, Morris QD, Blencowe BJ, Frey BJ. Inferring global levels of alternative splicing isoforms using a generative model of microarray data. Bioinformatics (Oxford, England). 22: 606-13. PMID 16403798 DOI: 10.1093/Bioinformatics/Btk028 |
0.329 |
|
| 2005 |
McCracken S, Longman D, Marcon E, Moens P, Downey M, Nickerson JA, Jessberger R, Wilde A, Caceres JF, Emili A, Blencowe BJ. Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin. The Journal of Biological Chemistry. 280: 42227-36. PMID 16159877 DOI: 10.1074/Jbc.M507410200 |
0.402 |
|
| 2005 |
Frey BJ, Mohammad N, Morris QD, Zhang W, Robinson MD, Mnaimneh S, Chang R, Pan Q, Sat E, Rossant J, Bruneau BG, Aubin JE, Blencowe BJ, Hughes TR. Genome-wide analysis of mouse transcripts using exon microarrays and factor graphs. Nature Genetics. 37: 991-6. PMID 16127451 DOI: 10.1038/Ng1630 |
0.314 |
|
| 2005 |
Babak T, Blencowe BJ, Hughes TR. A systematic search for new mammalian noncoding RNAs indicates little conserved intergenic transcription. Bmc Genomics. 6: 104. PMID 16083503 DOI: 10.1186/1471-2164-6-104 |
0.376 |
|
| 2005 |
Rosonina E, Ip JY, Calarco JA, Bakowski MA, Emili A, McCracken S, Tucker P, Ingles CJ, Blencowe BJ. Role for PSF in mediating transcriptional activator-dependent stimulation of pre-mRNA processing in vivo. Molecular and Cellular Biology. 25: 6734-46. PMID 16024807 DOI: 10.1128/Mcb.25.15.6734-6746.2005 |
0.807 |
|
| 2004 |
Pan Q, Shai O, Misquitta C, Zhang W, Saltzman AL, Mohammad N, Babak T, Siu H, Hughes TR, Morris QD, Frey BJ, Blencowe BJ. Revealing global regulatory features of mammalian alternative splicing using a quantitative microarray platform. Molecular Cell. 16: 929-41. PMID 15610736 DOI: 10.1016/J.Molcel.2004.12.004 |
0.768 |
|
| 2004 |
Zhang W, Morris QD, Chang R, Shai O, Bakowski MA, Mitsakakis N, Mohammad N, Robinson MD, Zirngibl R, Somogyi E, Laurin N, Eftekharpour E, Sat E, Grigull J, Pan Q, ... ... Blencowe BJ, et al. The functional landscape of mouse gene expression. Journal of Biology. 3: 21. PMID 15588312 DOI: 10.1186/Jbiol16 |
0.328 |
|
| 2004 |
Custódio N, Carvalho C, Condado I, Antoniou M, Blencowe BJ, Carmo-Fonseca M. In vivo recruitment of exon junction complex proteins to transcription sites in mammalian cell nuclei. Rna (New York, N.Y.). 10: 622-33. PMID 15037772 DOI: 10.1261/Rna.5258504 |
0.418 |
|
| 2004 |
Rosonina E, Blencowe BJ. Analysis of the requirement for RNA polymerase II CTD heptapeptide repeats in pre-mRNA splicing and 3'-end cleavage. Rna (New York, N.Y.). 10: 581-9. PMID 15037767 DOI: 10.1261/Rna.5207204 |
0.778 |
|
| 2003 |
McCracken S, Longman D, Johnstone IL, Cáceres JF, Blencowe BJ. An evolutionarily conserved role for SRm160 in 3'-end processing that functions independently of exon junction complex formation. The Journal of Biological Chemistry. 278: 44153-60. PMID 12944400 DOI: 10.1074/Jbc.M306856200 |
0.387 |
|
| 2003 |
Rosonina E, Bakowski MA, McCracken S, Blencowe BJ. Transcriptional activators control splicing and 3'-end cleavage levels. The Journal of Biological Chemistry. 278: 43034-40. PMID 12939267 DOI: 10.1074/Jbc.M307289200 |
0.767 |
|
| 2003 |
Szymczyna BR, Bowman J, McCracken S, Pineda-Lucena A, Lu Y, Cox B, Lambermon M, Graveley BR, Arrowsmith CH, Blencowe BJ. Structure and function of the PWI motif: a novel nucleic acid-binding domain that facilitates pre-mRNA processing. Genes & Development. 17: 461-75. PMID 12600940 DOI: 10.1101/Gad.1060403 |
0.318 |
|
| 2003 |
Blencowe BJ. Splicing regulation: the cell cycle connection. Current Biology : Cb. 13: R149-51. PMID 12593819 DOI: 10.1016/S0960-9822(03)00079-4 |
0.417 |
|
| 2002 |
Emili A, Shales M, McCracken S, Xie W, Tucker PW, Kobayashi R, Blencowe BJ, Ingles CJ. Splicing and transcription-associated proteins PSF and p54nrb/nonO bind to the RNA polymerase II CTD. Rna (New York, N.Y.). 8: 1102-11. PMID 12358429 DOI: 10.1017/S1355838202025037 |
0.413 |
|
| 2002 |
Rosonina E, Blencowe BJ. Gene expression: the close coupling of transcription and splicing. Current Biology : Cb. 12: R319-21. PMID 12007432 DOI: 10.1016/S0960-9822(02)00829-1 |
0.763 |
|
| 2002 |
Blencowe BJ. Transcription: surprising role for an elusive small nuclear RNA. Current Biology : Cb. 12: R147-9. PMID 11864590 DOI: 10.1016/S0960-9822(02)00711-X |
0.334 |
|
| 2002 |
McCracken S, Lambermon M, Blencowe BJ. SRm160 splicing coactivator promotes transcript 3'-end cleavage. Molecular and Cellular Biology. 22: 148-60. PMID 11739730 DOI: 10.1128/MCB.22.1.148-160.2002 |
0.42 |
|
| 2001 |
Boucher L, Ouzounis CA, Enright AJ, Blencowe BJ. A genome-wide survey of RS domain proteins. Rna (New York, N.Y.). 7: 1693-701. PMID 11780626 |
0.313 |
|
| 2001 |
Longman D, McGarvey T, McCracken S, Johnstone IL, Blencowe BJ, Cáceres JF. Multiple interactions between SRm160 and SR family proteins in enhancer-dependent splicing and development of C. elegans. Current Biology : Cb. 11: 1923-33. PMID 11747818 DOI: 10.1016/S0960-9822(01)00589-9 |
0.336 |
|
| 2001 |
Rodrigues JP, Rode M, Gatfield D, Blencowe BJ, Carmo-Fonseca M, Izaurralde E. REF proteins mediate the export of spliced and unspliced mRNAs from the nucleus. Proceedings of the National Academy of Sciences of the United States of America. 98: 1030-5. PMID 11158589 DOI: 10.1073/Pnas.98.3.1030 |
0.395 |
|
| 2000 |
McGarvey T, Rosonina E, McCracken S, Li Q, Arnaout R, Mientjes E, Nickerson JA, Awrey D, Greenblatt J, Grosveld G, Blencowe BJ. The acute myeloid leukemia-associated protein, DEK, forms a splicing-dependent interaction with exon-product complexes. The Journal of Cell Biology. 150: 309-20. PMID 10908574 DOI: 10.1083/Jcb.150.2.309 |
0.76 |
|
| 2000 |
Blencowe BJ, Baurén G, Eldridge AG, Issner R, Nickerson JA, Rosonina E, Sharp PA. The SRm160/300 splicing coactivator subunits. Rna (New York, N.Y.). 6: 111-20. PMID 10668804 DOI: 10.1017/S1355838200991982 |
0.809 |
|
| 1999 |
Li Y, Blencowe BJ. Distinct factor requirements for exonic splicing enhancer function and binding of U2AF to the polypyrimidine tract. The Journal of Biological Chemistry. 274: 35074-9. PMID 10574987 DOI: 10.1074/jbc.274.49.35074 |
0.413 |
|
| 1999 |
Blencowe BJ, Lamond AI. Purification and depletion of RNP particles by antisense affinity chromatography. Methods in Molecular Biology (Clifton, N.J.). 118: 275-87. PMID 10549530 DOI: 10.1385/1-59259-676-2:275 |
0.554 |
|
| 1999 |
Blencowe BJ, Bowman JA, McCracken S, Rosonina E. SR-related proteins and the processing of messenger RNA precursors. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 77: 277-91. PMID 10546891 DOI: 10.1139/O99-048 |
0.766 |
|
| 1999 |
Eldridge AG, Li Y, Sharp PA, Blencowe BJ. The SRm160/300 splicing coactivator is required for exon-enhancer function. Proceedings of the National Academy of Sciences of the United States of America. 96: 6125-30. PMID 10339552 DOI: 10.1073/Pnas.96.11.6125 |
0.698 |
|
| 1999 |
Eldridge A, Issner R, Li Y, Reifenberg E, Sharp PA, Blencowe BJ. Role of the SRm160/300 splicing coactivator in exon-enhancer function Biochemistry and Cell Biology. 77: 393. DOI: 10.1139/O99-903J |
0.611 |
|
| 1998 |
Blencowe BJ, Issner R, Nickerson JA, Sharp PA. A coactivator of pre-mRNA splicing. Genes & Development. 12: 996-1009. PMID 9531537 DOI: 10.1101/Gad.12.7.996 |
0.656 |
|
| 1996 |
Mortillaro MJ, Blencowe BJ, Wei X, Nakayasu H, Du L, Warren SL, Sharp PA, Berezney R. A hyperphosphorylated form of the large subunit of RNA polymerase II is associated with splicing complexes and the nuclear matrix. Proceedings of the National Academy of Sciences of the United States of America. 93: 8253-7. PMID 8710856 DOI: 10.1073/Pnas.93.16.8253 |
0.656 |
|
| 1995 |
Blencowe BJ, Issner R, Kim J, Mccaw P, Sharp PA. New proteins related to the Ser-Arg family of splicing factors. Rna (New York, N.Y.). 1: 852-65. PMID 7493330 |
0.616 |
|
| 1994 |
Crispino JD, Blencowe BJ, Sharp PA. Complementation by SR proteins of pre-mRNA splicing reactions depleted of U1 snRNP. Science (New York, N.Y.). 265: 1866-9. PMID 8091213 DOI: 10.1126/Science.8091213 |
0.703 |
|
| 1994 |
Blencowe BJ, Nickerson JA, Issner R, Penman S, Sharp PA. Association of nuclear matrix antigens with exon-containing splicing complexes. The Journal of Cell Biology. 127: 593-607. PMID 7962048 DOI: 10.1083/Jcb.127.3.593 |
0.59 |
|
| 1993 |
Blencowe BJ, Carmo-Fonseca M, Behrens SE, Lührmann R, Lamond AI. Interaction of the human autoantigen p150 with splicing snRNPs. Journal of Cell Science. 105: 685-97. PMID 8408296 |
0.616 |
|
| 1991 |
Lamm GM, Blencowe BJ, Sproat BS, Iribarren AM, Ryder U, Lamond AI. Antisense probes containing 2-aminoadenosine allow efficient depletion of U5 snRNP from HeLa splicing extracts. Nucleic Acids Research. 19: 3193-8. PMID 1648201 |
0.649 |
|
| 1990 |
Barabino SM, Blencowe BJ, Ryder U, Sproat BS, Lamond AI. Targeted snRNP depletion reveals an additional role for mammalian U1 snRNP in spliceosome assembly. Cell. 63: 293-302. PMID 2170025 DOI: 10.1016/0092-8674(90)90162-8 |
0.675 |
|
| 1990 |
Lamond AI, Barabino S, Blencowe BJ, Sproat B, Ryder U. Studying pre-mRNA splicing using antisense 2-OMe RNA oligonucleotides. Molecular Biology Reports. 14: 201. PMID 1694562 DOI: 10.1007/BF00360473 |
0.678 |
|
| 1989 |
Barabino SM, Sproat BS, Ryder U, Blencowe BJ, Lamond AI. Mapping U2 snRNP--pre-mRNA interactions using biotinylated oligonucleotides made of 2'-OMe RNA. The Embo Journal. 8: 4171-8. PMID 2531659 |
0.682 |
|
| 1989 |
Blencowe BJ, Sproat BS, Ryder U, Barabino S, Lamond AI. Antisense probing of the human U4/U6 snRNP with biotinylated 2'-OMe RNA oligonucleotides. Cell. 59: 531-9. PMID 2478298 DOI: 10.1016/0092-8674(89)90036-6 |
0.649 |
|
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