| Year |
Citation |
Score |
| 2021 |
Jacob Berger A, Gigi E, Kupershmidt L, Meir Z, Gavert N, Zwang Y, Prior A, Gilad S, Harush U, Haviv I, Stemmer SM, Blum G, Merquiol E, Mardamshina M, Kaminski Strauss S, et al. IRS1 phosphorylation underlies the non-stochastic probability of cancer cells to persist during EGFR inhibition therapy. Nature Cancer. 2: 1055-1070. PMID 35121883 DOI: 10.1038/s43018-021-00261-1 |
0.331 |
|
| 2020 |
Ben-Hamo R, Jacob Berger A, Gavert N, Miller M, Pines G, Oren R, Pikarsky E, Benes CH, Neuman T, Zwang Y, Efroni S, Getz G, Straussman R. Predicting and affecting response to cancer therapy based on pathway-level biomarkers. Nature Communications. 11: 3296. PMID 32620799 DOI: 10.1038/S41467-020-17090-Y |
0.308 |
|
| 2017 |
Zwang Y, Jonas O, Chen C, Rinne ML, Doench JG, Piccioni F, Tan L, Huang HT, Wang J, Ham YJ, O'Connell J, Bhola P, Doshi M, Whitman M, Cima M, et al. Synergistic interactions with PI3K inhibition that induce apoptosis. Elife. 6. PMID 28561737 DOI: 10.7554/Elife.24523 |
0.375 |
|
| 2017 |
Tarcic O, Granit RZ, Pateras IS, Masury H, Maly B, Zwang Y, Yarden Y, Gorgoulis VG, Pikarsky E, Ben-Porath I, Oren M. RNF20 and histone H2B ubiquitylation exert opposing effects in Basal-Like versus luminal breast cancer. Cell Death and Differentiation. PMID 28157208 DOI: 10.1038/Cdd.2016.126 |
0.515 |
|
| 2015 |
Baratta MG, Schinzel AC, Zwang Y, Bandopadhayay P, Bowman-Colin C, Kutt J, Curtis J, Piao H, Wong LC, Kung AL, Beroukhim R, Bradner JE, Drapkin R, Hahn WC, Liu JF, et al. An in-tumor genetic screen reveals that the BET bromodomain protein, BRD4, is a potential therapeutic target in ovarian carcinoma. Proceedings of the National Academy of Sciences of the United States of America. 112: 232-7. PMID 25535366 DOI: 10.1073/Pnas.1422165112 |
0.327 |
|
| 2015 |
Zwang Y, Chen C, Hahn WC. Abstract C73: A drug-modifier whole-genome shRNA screen identifies novel synthetic lethal interactions with PI3K inhibition in breast cancer Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-C73 |
0.373 |
|
| 2014 |
Shao DD, Xue W, Krall EB, Bhutkar A, Piccioni F, Wang X, Schinzel AC, Sood S, Rosenbluh J, Kim JW, Zwang Y, Roberts TM, Root DE, Jacks T, Hahn WC. KRAS and YAP1 converge to regulate EMT and tumor survival. Cell. 158: 171-84. PMID 24954536 DOI: 10.1016/J.Cell.2014.06.004 |
0.393 |
|
| 2012 |
Lovejoy CA, Li W, Reisenweber S, Thongthip S, Bruno J, de Lange T, De S, Petrini JH, Sung PA, Jasin M, Rosenbluh J, Zwang Y, Weir BA, Hatton C, Ivanova E, et al. Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway. Plos Genetics. 8: e1002772. PMID 22829774 DOI: 10.1371/Journal.Pgen.1002772 |
0.331 |
|
| 2012 |
Zwang Y, Oren M, Yarden Y. Consistency test of the cell cycle: roles for p53 and EGR1. Cancer Research. 72: 1051-4. PMID 22315347 DOI: 10.1158/0008-5472.Can-11-3382 |
0.523 |
|
| 2012 |
Tarcic G, Avraham R, Pines G, Amit I, Shay T, Lu Y, Zwang Y, Katz M, Ben-Chetrit N, Jacob-Hirsch J, Virgilio L, Rechavi G, Mavrothalassitis G, Mills GB, Domany E, et al. EGR1 and the ERK-ERF axis drive mammary cell migration in response to EGF. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 1582-92. PMID 22198386 DOI: 10.1096/Fj.11-194654 |
0.608 |
|
| 2011 |
Zwang Y, Sas-Chen A, Drier Y, Shay T, Avraham R, Lauriola M, Shema E, Lidor-Nili E, Jacob-Hirsch J, Amariglio N, Lu Y, Mills GB, Rechavi G, Oren M, Domany E, et al. Two phases of mitogenic signaling unveil roles for p53 and EGR1 in elimination of inconsistent growth signals. Molecular Cell. 42: 524-35. PMID 21596316 DOI: 10.1016/J.Molcel.2011.04.017 |
0.538 |
|
| 2010 |
Pines G, Huang PH, Zwang Y, White FM, Yarden Y. EGFRvIV: a previously uncharacterized oncogenic mutant reveals a kinase autoinhibitory mechanism. Oncogene. 29: 5850-60. PMID 20676128 DOI: 10.1038/Onc.2010.313 |
0.654 |
|
| 2010 |
Avraham R, Sas-Chen A, Manor O, Steinfeld I, Shalgi R, Tarcic G, Bossel N, Zeisel A, Amit I, Zwang Y, Enerly E, Russnes HG, Biagioni F, Mottolese M, Strano S, et al. EGF decreases the abundance of microRNAs that restrain oncogenic transcription factors. Science Signaling. 3: ra43. PMID 20516477 DOI: 10.1126/Scisignal.2000876 |
0.609 |
|
| 2009 |
Zwang Y, Yarden Y. Systems biology of growth factor-induced receptor endocytosis. Traffic (Copenhagen, Denmark). 10: 349-63. PMID 19183301 DOI: 10.1111/J.1600-0854.2008.00870.X |
0.65 |
|
| 2007 |
Shtiegman K, Kochupurakkal BS, Zwang Y, Pines G, Starr A, Vexler A, Citri A, Katz M, Lavi S, Ben-Basat Y, Benjamin S, Corso S, Gan J, Yosef RB, Giordano S, et al. Defective ubiquitinylation of EGFR mutants of lung cancer confers prolonged signaling. Oncogene. 26: 6968-78. PMID 17486068 DOI: 10.1038/Sj.Onc.1210503 |
0.721 |
|
| 2007 |
Zwang Y, Yarden Y. Growth factor signalling: ample opportunities for pharmaceutical interventions in oncology European Journal of Cancer, Supplement. 5: 427-429. DOI: 10.1016/S1359-6349(07)70086-1 |
0.517 |
|
| 2006 |
Zwang Y, Yarden Y. p38 MAP kinase mediates stress-induced internalization of EGFR: implications for cancer chemotherapy. The Embo Journal. 25: 4195-206. PMID 16932740 DOI: 10.1038/Sj.Emboj.7601297 |
0.644 |
|
| 2006 |
Oved S, Mosesson Y, Zwang Y, Santonico E, Shtiegman K, Marmor MD, Kochupurakkal BS, Katz M, Lavi S, Cesareni G, Yarden Y. Conjugation to Nedd8 instigates ubiquitylation and down-regulation of activated receptor tyrosine kinases. The Journal of Biological Chemistry. 281: 21640-51. PMID 16735510 DOI: 10.1074/Jbc.M513034200 |
0.688 |
|
| 2005 |
Rubin C, Zwang Y, Vaisman N, Ron D, Yarden Y. Phosphorylation of carboxyl-terminal tyrosines modulates the specificity of Sprouty-2 inhibition of different signaling pathways. The Journal of Biological Chemistry. 280: 9735-44. PMID 15637081 DOI: 10.1074/Jbc.M408308200 |
0.649 |
|
| 2004 |
Amit I, Yakir L, Katz M, Zwang Y, Marmor MD, Citri A, Shtiegman K, Alroy I, Tuvia S, Reiss Y, Roubini E, Cohen M, Wides R, Bacharach E, Schubert U, et al. Tal, a Tsg101-specific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus budding. Genes & Development. 18: 1737-52. PMID 15256501 DOI: 10.1101/Gad.294904 |
0.711 |
|
| 2003 |
Shelly M, Mosesson Y, Citri A, Lavi S, Zwang Y, Melamed-Book N, Aroeti B, Yarden Y. Polar expression of ErbB-2/HER2 in epithelia. Bimodal regulation by Lin-7. Developmental Cell. 5: 475-86. PMID 12967566 DOI: 10.1016/J.Devcel.2003.08.001 |
0.707 |
|
| 2003 |
Mosesson Y, Shtiegman K, Katz M, Zwang Y, Vereb G, Szollosi J, Yarden Y. Endocytosis of receptor tyrosine kinases is driven by monoubiquitylation, not polyubiquitylation. The Journal of Biological Chemistry. 278: 21323-6. PMID 12719435 DOI: 10.1074/Jbc.C300096200 |
0.685 |
|
| 2003 |
Rubin C, Litvak V, Medvedovsky H, Zwang Y, Lev S, Yarden Y. Sprouty fine-tunes EGF signaling through interlinked positive and negative feedback loops. Current Biology : Cb. 13: 297-307. PMID 12593795 DOI: 10.1016/S0960-9822(03)00053-8 |
0.737 |
|
| 2002 |
Goldberg Z, Vogt Sionov R, Berger M, Zwang Y, Perets R, Van Etten RA, Oren M, Taya Y, Haupt Y. Tyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulation. The Embo Journal. 21: 3715-27. PMID 12110584 DOI: 10.1093/Emboj/Cdf384 |
0.359 |
|
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