| Year | Citation | Score | |||
|---|---|---|---|---|---|
| 2023 | Nakashima F, Giménez-Bastida J, Luis P, Presley S, Boer R, Chiusa M, Shibata T, Sulikowski G, Pozzi A, Schneider C. The 5-lipoxygenase/cyclooxygenase-2 (5-LOX/COX-2) cross-over metabolite, hemiketal E, enhances VEGFR2 activation and promotes angiogenesis. The Journal of Biological Chemistry. 103050. PMID 36813233 DOI: 10.1016/j.jbc.2023.103050 | 0.331 | |||
| 2022 | Haake SM, Plosa EJ, Kropski JA, Venton LA, Reddy A, Bock F, Chang BT, Luna AJ, Nabukhotna K, Xu ZQ, Prather RA, Lee S, Tanjore H, Polosukhin VV, Viquez OM, ... ... Pozzi A, et al. Ligand-independent integrin beta1 signaling supports lung adenocarcinoma development. Jci Insight. PMID 35763345 DOI: 10.1172/jci.insight.154098 | 0.334 | |||
| 2022 | Borza CM, Bolas G, Zhang X, Browning Monroe MB, Zhang MZ, Meiler J, Skwark MJ, Harris RC, Lapierre LA, Goldenring JR, Hook M, Rivera J, Brown KL, Leitinger B, Tyska MJ, ... ... Pozzi A, et al. The Collagen Receptor Discoidin Domain Receptor 1b Enhances Integrin β1-Mediated Cell Migration by Interacting With Talin and Promoting Rac1 Activation. Frontiers in Cell and Developmental Biology. 10: 836797. PMID 35309920 DOI: 10.3389/fcell.2022.836797 | 0.362 | |||
| 2020 | Chiusa M, Hu W, Zienkiewicz J, Chen X, Zhang MZ, Harris RC, Vanacore RM, Bentz JA, Remuzzi G, Benigni A, Fogo AB, Luo W, Mili S, Wilson MH, Zent R, ... ... Pozzi A, et al. EGF receptor-mediated FUS phosphorylation promotes its nuclear translocation and fibrotic signaling. The Journal of Cell Biology. 219. PMID 32678881 DOI: 10.1083/Jcb.202001120 | 0.378 | |||
| 2020 | Aschner Y, Nelson M, Brenner M, Roybal H, Beke K, Meador C, Foster D, Reynolds PR, Anderson K, Redente EF, Matsuda J, Riches DWH, Groshong SD, Pozzi A, Sap J, et al. Protein Tyrosine Phosphatase-α Amplifies TGF-β-Dependent Pro-Fibrotic Signaling in Lung Fibroblasts. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 32491951 DOI: 10.1152/Ajplung.00235.2019 | 0.392 | |||
| 2020 | Jeffries DE, Borza CM, Blobaum AL, Pozzi A, Lindsley CW. Discovery of VU6015929: A Selective Discoidin Domain Receptor 1/2 (DDR1/2) Inhibitor to Explore the Role of DDR1 in Antifibrotic Therapy. Acs Medicinal Chemistry Letters. 11: 29-33. PMID 31938459 DOI: 10.1021/Acsmedchemlett.9B00382 | 0.321 | |||
| 2019 | Plosa EJ, Benjamin JT, Sucre JM, Gulleman PM, Gleaves LA, Han W, Kook S, Polosukhin VV, Haake SM, Guttentag SH, Young LR, Pozzi A, Blackwell TS, Zent R. β1 integrin regulates adult lung alveolar epithelial cell inflammation. Jci Insight. PMID 31873073 DOI: 10.1172/Jci.Insight.129259 | 0.379 | |||
| 2019 | Chiusa M, Hu W, Liao HJ, Su Y, Borza CM, de Caestecker MP, Skrypnyk NI, Fogo AB, Pedchenko V, Li X, Zhang MZ, Hudson BG, Basak T, Vanacore RM, Zent R, ... Pozzi A, et al. The Extracellular Matrix Receptor Discoidin Domain Receptor 1 Regulates Collagen Transcription by Translocating to the Nucleus. Journal of the American Society of Nephrology : Jasn. PMID 31383731 DOI: 10.1681/Asn.2018111160 | 0.37 | |||
| 2019 | Zhang MZ, Sasaki K, Li Y, Li Z, Pan Y, Jin GN, Wang Y, Niu A, Wang S, Fan X, Chen JC, Borza C, Yang H, Pozzi A, Fogo AB, et al. The Role of the EGF Receptor in Sex Differences in Kidney Injury. Journal of the American Society of Nephrology : Jasn. PMID 31292196 DOI: 10.1681/Asn.2018121244 | 0.318 | |||
| 2019 | CAPPEL DA, POZZI A, ZENT R, WASSERMAN D. 1944-P: Muscle a-Parvin Is Not Necessary for Integrin-Linked Kinase Related Insulin Resistance in Diet-Induced Obese Mice Diabetes. 68: 1944-P. DOI: 10.2337/Db19-1944-P | 0.314 | |||
| 2019 | Trefts E, Roby DA, Pozzi A, Zent R, Wasserman D. 1904-P: The Hepatocyte Integrin ß1 Subunit Links ECM-Integrin Signaling to Insulin Resistance in Obese Mice Diabetes. 68. DOI: 10.2337/Db19-1904-P | 0.346 | |||
| 2018 | Sausville LN, Williams SM, Pozzi A. Cytochrome P450 epoxygenases and cancer: A genetic and a molecular perspective. Pharmacology & Therapeutics. PMID 30521883 DOI: 10.1016/J.Pharmthera.2018.11.009 | 0.335 | |||
| 2018 | Yazlovitskaya EM, Viquez O, Tu T, De Arcangelis A, Georges-Labouesse E, Sonnenberg A, Pozzi A, Zent R. The laminin binding α3 and α6 integrins cooperate to promote epithelial cell adhesion and growth. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 30193894 DOI: 10.1016/J.Matbio.2018.08.010 | 0.383 | |||
| 2018 | Sausville LN, Gangadhariah M, Chiusa M, Mei S, Wei S, Zent R, Luther JM, Shuey MM, Capdevila JH, Falck JR, Guengerich FP, Williams SM, Pozzi A. The cytochrome P450 slow metabolizers CYP2C9*2 and CYP2C9*3 directly regulate tumorigenesis via reduced epoxyeicosatrienoic acid production. Cancer Research. PMID 30012669 DOI: 10.1158/0008-5472.Can-17-3977 | 0.391 | |||
| 2017 | Mathew S, Palamuttam RJ, Mernaugh G, Ramalingam H, Lu Z, Zhang MZ, Ishibe S, Critchley DR, Fässler R, Pozzi A, Sanders CR, Carroll TJ, Zent R. Talin regulates integrin β1 dependent and independent cell functions in ureteric bud development. Development (Cambridge, England). PMID 28993400 DOI: 10.1242/Dev.149914 | 0.429 | |||
| 2016 | Viquez OM, Yazlovitskaya EM, Tu T, Mernaugh G, Secades P, McKee KK, Quaranta V, Yurchenco P, Gewin LC, Sonnenberg A, Pozzi A, Zent R. Integrin alpha6 maintains the structural integrity of the kidney collecting system. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 28043890 DOI: 10.1016/J.Matbio.2016.12.003 | 0.399 | |||
| 2016 | Pozzi A, Yurchenco PD, Iozzo RV. The nature and biology of basement membranes. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 28040522 DOI: 10.1016/J.Matbio.2016.12.009 | 0.317 | |||
| 2016 | Borza CM, Su Y, Tran TL, Yu L, Steyns N, Temple KJ, Skwark MJ, Meiler J, Lindsley CW, Hicks BR, Leitinger B, Zent R, Pozzi A. Discoidin domain receptor 1 kinase activity is required for regulating collagen IV synthesis. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 27915093 DOI: 10.1016/J.Matbio.2016.11.009 | 0.431 | |||
| 2016 | Gewin L, Zent R, Pozzi A. Progression of chronic kidney disease: too much cellular talk causes damage. Kidney International. PMID 27773427 DOI: 10.1016/J.Kint.2016.08.025 | 0.393 | |||
| 2016 | Cummings CF, Pedchenko V, Brown KL, Colon S, Rafi M, Jones-Paris C, Pokydeshava E, Liu M, Pastor-Pareja JC, Stothers C, Ero-Tolliver IA, McCall AS, Vanacore R, Bhave G, Santoro S, ... ... Pozzi A, et al. Extracellular chloride signals collagen IV network assembly during basement membrane formation. The Journal of Cell Biology. 213: 479-94. PMID 27216258 DOI: 10.1083/Jcb.201510065 | 0.301 | |||
| 2016 | Mickiewicz B, Shin SY, Pozzi A, Vogel HJ, Clark AL. Serum metabolite profiles are altered by erlotinib treatment and the integrin α1-null genotype, but not by post traumatic osteoarthritis. Journal of Proteome Research. PMID 26784366 DOI: 10.1021/Acs.Jproteome.5B00719 | 0.341 | |||
| 2015 | Borza CM, Chen X, Zent R, Pozzi A. Cell Receptor-Basement Membrane Interactions in Health and Disease: A Kidney-Centric View. Current Topics in Membranes. 76: 231-53. PMID 26610916 DOI: 10.1016/Bs.Ctm.2015.07.003 | 0.368 | |||
| 2015 | Elias BC, Das A, Parekh DV, Mernaugh G, Adams R, Yang Z, Brakebusch C, Pozzi A, Marciano DK, Carroll TJ, Zent R. Cdc42 regulates epithelial cell polarity and cytoskeletal function in kidney tubule development. Journal of Cell Science. PMID 26490995 DOI: 10.1242/Jcs.164509 | 0.359 | |||
| 2015 | Chang J, Xue M, Yang S, Yao B, Zhang B, Chen X, Pozzi A, Zhang MZ. Inhibition of 11β-Hydroxysteroid Dehydrogenase Type II Suppresses Lung Carcinogenesis by Blocking Tumor COX-2 Expression as Well as the ERK and mTOR Signaling Pathways. Plos One. 10: e0127030. PMID 26011146 DOI: 10.1371/Journal.Pone.0127030 | 0.372 | |||
| 2015 | Yazlovitskaya EM, Tseng HY, Viquez O, Tu T, Mernaugh G, McKee KK, Riggins K, Quaranta V, Pathak A, Carter BD, Yurchenco P, Sonnenberg A, Böttcher RT, Pozzi A, Zent R. Integrin α3β1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of Akt. Molecular Biology of the Cell. 26: 1857-74. PMID 25808491 DOI: 10.1091/Mbc.E14-07-1203 | 0.424 | |||
| 2015 | Wang H, Chen X, Su Y, Paueksakon P, Hu W, Zhang MZ, Harris RC, Blackwell TS, Zent R, Pozzi A. p47(phox) contributes to albuminuria and kidney fibrosis in mice. Kidney International. 87: 948-62. PMID 25565313 DOI: 10.1038/Ki.2014.386 | 0.351 | |||
| 2015 | Kothiwale S, Borza CM, Lowe EW, Pozzi A, Meiler J. Discoidin domain receptor 1 (DDR1) kinase as target for structure-based drug discovery. Drug Discovery Today. 20: 255-61. PMID 25284748 DOI: 10.1016/J.Drudis.2014.09.025 | 0.388 | |||
| 2015 | Gangadhariah MH, Luther JM, Garcia V, Paueksakon P, Zhang MZ, Hayward SW, Love HD, Falck JR, Manthati VL, Imig JD, Schwartzman ML, Zent R, Capdevila JH, Pozzi A. Hypertension is a major contributor to 20-hydroxyeicosatetraenoic acid-mediated kidney injury in diabetic nephropathy. Journal of the American Society of Nephrology : Jasn. 26: 597-610. PMID 25071086 DOI: 10.1681/Asn.2013090980 | 0.319 | |||
| 2015 | Elias BC, Das A, Parekh DV, Mernaugh G, Adams R, Yang Z, Brakebusch C, Pozzi A, Marciano DK, Carroll TJ, Zent R. Cdc42 regulates epithelial cell polarity and cytoskeletal function during kidney tubule development Development. 142. DOI: 10.1242/Dev.133611 | 0.339 | |||
| 2014 | Chen X, Wang H, Liao HJ, Hu W, Gewin L, Mernaugh G, Zhang S, Zhang ZY, Vega-Montoto L, Vanacore RM, Fässler R, Zent R, Pozzi A. Integrin-mediated type II TGF-β receptor tyrosine dephosphorylation controls SMAD-dependent profibrotic signaling. The Journal of Clinical Investigation. 124: 3295-310. PMID 24983314 DOI: 10.1172/Jci71668 | 0.417 | |||
| 2014 | Miller CG, Pozzi A, Zent R, Schwarzbauer JE. Effects of high glucose on integrin activity and fibronectin matrix assembly by mesangial cells. Molecular Biology of the Cell. 25: 2342-50. PMID 24943838 DOI: 10.1091/Mbc.E14-03-0800 | 0.355 | |||
| 2014 | Irvin MW, Zijlstra A, Wikswo JP, Pozzi A. Techniques and assays for the study of angiogenesis. Experimental Biology and Medicine (Maywood, N.J.). 239: 1476-88. PMID 24872440 DOI: 10.1177/1535370214529386 | 0.326 | |||
| 2014 | Reinert RB, Cai Q, Hong JY, Plank JL, Aamodt K, Prasad N, Aramandla R, Dai C, Levy SE, Pozzi A, Labosky PA, Wright CV, Brissova M, Powers AC. Vascular endothelial growth factor coordinates islet innervation via vascular scaffolding. Development (Cambridge, England). 141: 1480-91. PMID 24574008 DOI: 10.1242/Dev.098657 | 0.324 | |||
| 2014 | Elias BC, Mathew S, Srichai MB, Palamuttam R, Bulus N, Mernaugh G, Singh AB, Sanders CR, Harris RC, Pozzi A, Zent R. The integrin β1 subunit regulates paracellular permeability of kidney proximal tubule cells. The Journal of Biological Chemistry. 289: 8532-44. PMID 24509849 DOI: 10.1074/Jbc.M113.526509 | 0.371 | |||
| 2014 | Jablonski CL, Ferguson S, Pozzi A, Clark AL. Integrin α1β1 participates in chondrocyte transduction of osmotic stress. Biochemical and Biophysical Research Communications. 445: 184-90. PMID 24495803 DOI: 10.1016/J.Bbrc.2014.01.157 | 0.362 | |||
| 2014 | Borza CM, Pozzi A. Discoidin domain receptors in disease. Matrix Biology : Journal of the International Society For Matrix Biology. 34: 185-92. PMID 24361528 DOI: 10.1016/J.Matbio.2013.12.002 | 0.416 | |||
| 2014 | Skrypnyk N, Chen X, Hu W, Su Y, Mont S, Yang S, Gangadhariah M, Wei S, Falck JR, Jat JL, Zent R, Capdevila JH, Pozzi A. PPARα activation can help prevent and treat non-small cell lung cancer. Cancer Research. 74: 621-31. PMID 24302581 DOI: 10.1158/0008-5472.Can-13-1928 | 0.345 | |||
| 2014 | Pozzi A, Zent R. New insights into disorders of basement membranes and integrins of the kidney Drug Discovery Today: Disease Models. 11: 37-44. DOI: 10.1016/J.Ddmod.2014.07.003 | 0.385 | |||
| 2013 | Jiang L, Yang S, Yin H, Fan X, Wang S, Yao B, Pozzi A, Chen X, Harris RC, Zhang MZ. Epithelial-specific deletion of 11β-HSD2 hinders Apcmin/+ mouse tumorigenesis. Molecular Cancer Research : McR. 11: 1040-50. PMID 23741059 DOI: 10.1158/1541-7786.Mcr-13-0084-T | 0.38 | |||
| 2013 | Pozzi A, Zent R. Integrins in kidney disease. Journal of the American Society of Nephrology : Jasn. 24: 1034-9. PMID 23641054 DOI: 10.1681/Asn.2013010012 | 0.383 | |||
| 2012 | Gewin L, Vadivelu S, Neelisetty S, Srichai MB, Paueksakon P, Pozzi A, Harris RC, Zent R. Deleting the TGF-β receptor attenuates acute proximal tubule injury. Journal of the American Society of Nephrology : Jasn. 23: 2001-11. PMID 23160515 DOI: 10.1681/Asn.2012020139 | 0.353 | |||
| 2012 | Carpenter G, Pozzi A. Cell responses to growth factors: the role of receptor tyrosine kinase intracellular domain fragments. Science Signaling. 5: pe42. PMID 23012654 DOI: 10.1126/Scisignal.2003526 | 0.357 | |||
| 2012 | Pozzi A. PI3-kinase and TGF-β in glomerular nephropathy: which comes first? Kidney International. 82: 507-9. PMID 22892855 DOI: 10.1038/Ki.2012.154 | 0.303 | |||
| 2012 | Shi M, Pedchenko V, Greer BH, Van Horn WD, Santoro SA, Sanders CR, Hudson BG, Eichman BF, Zent R, Pozzi A. Enhancing integrin α1 inserted (I) domain affinity to ligand potentiates integrin α1β1-mediated down-regulation of collagen synthesis. The Journal of Biological Chemistry. 287: 35139-52. PMID 22888006 DOI: 10.1074/Jbc.M112.358648 | 0.342 | |||
| 2012 | Mathew S, Lu Z, Palamuttam RJ, Mernaugh G, Hadziselimovic A, Chen J, Bulus N, Gewin LS, Voehler M, Meves A, Ballestrem C, Fässler R, Pozzi A, Sanders CR, Zent R. β1 integrin NPXY motifs regulate kidney collecting-duct development and maintenance by induced-fit interactions with cytosolic proteins. Molecular and Cellular Biology. 32: 4080-91. PMID 22869523 DOI: 10.1128/Mcb.00568-12 | 0.316 | |||
| 2012 | Bulus N, Feral C, Pozzi A, Zent R. CD98 increases renal epithelial cell proliferation by activating MAPKs. Plos One. 7: e40026. PMID 22768207 DOI: 10.1371/Journal.Pone.0040026 | 0.386 | |||
| 2012 | Borza CM, Su Y, Chen X, Yu L, Mont S, Chetyrkin S, Voziyan P, Hudson BG, Billings PC, Jo H, Bennett JS, Degrado WF, Eckes B, Zent R, Pozzi A. Inhibition of integrin α2β1 ameliorates glomerular injury. Journal of the American Society of Nephrology : Jasn. 23: 1027-38. PMID 22440900 DOI: 10.1681/Asn.2011040367 | 0.388 | |||
| 2012 | Borza CM, Pozzi A. The role of cell-extracellular matrix interactions in glomerular injury. Experimental Cell Research. 318: 1001-10. PMID 22417893 DOI: 10.1016/J.Yexcr.2012.02.033 | 0.394 | |||
| 2012 | Mathew S, Chen X, Pozzi A, Zent R. Integrins in renal development. Pediatric Nephrology (Berlin, Germany). 27: 891-900. PMID 21603909 DOI: 10.1007/S00467-011-1890-1 | 0.353 | |||
| 2012 | Schnaar R, Paulson JC, Macauley MS, Nycholat C, Pfrengle F, Rademacher C, Mahan A, Dionne K, Suscovich T, Alter G, Katoh T, Kiwamoto T, Brummet M, Bochner B, Tiemeyer M, ... ... Pozzi A, et al. Program and abstracts for the 2012 Joint Meeting of the Society for Glycobiology & American Society for Matrix Biology Glycobiology. 22: 1518-1650. DOI: 10.1093/Glycob/Cws127 | 0.312 | |||
| 2011 | Panigrahy D, Greene ER, Pozzi A, Wang DW, Zeldin DC. EET signaling in cancer. Cancer Metastasis Reviews. 30: 525-40. PMID 22009066 DOI: 10.1007/S10555-011-9315-Y | 0.321 | |||
| 2011 | Schneider C, Pozzi A. Cyclooxygenases and lipoxygenases in cancer. Cancer Metastasis Reviews. 30: 277-94. PMID 22002716 DOI: 10.1007/S10555-011-9310-3 | 0.433 | |||
| 2011 | Pozzi A, Zent R. Extracellular matrix receptors in branched organs. Current Opinion in Cell Biology. 23: 547-53. PMID 21561755 DOI: 10.1016/J.Ceb.2011.04.003 | 0.441 | |||
| 2011 | Li B, Pozzi A, Young PP. TNFalpha accelerates monocyte to endothelial transdifferentiation in tumors by the induction of integrin alpha5 expression and adhesion to fibronectin. Molecular Cancer Research : McR. 9: 702-11. PMID 21536688 DOI: 10.1158/1541-7786.Mcr-10-0484 | 0.424 | |||
| 2011 | Griesser M, Suzuki T, Tejera N, Mont S, Boeglin WE, Pozzi A, Schneider C. Biosynthesis of hemiketal eicosanoids by cross-over of the 5-lipoxygenase and cyclooxygenase-2 pathways. Proceedings of the National Academy of Sciences of the United States of America. 108: 6945-50. PMID 21482803 DOI: 10.1073/Pnas.1019473108 | 0.301 | |||
| 2011 | Srichai MB, Colleta H, Gewin L, Matrisian L, Abel TW, Koshikawa N, Seiki M, Pozzi A, Harris RC, Zent R. Membrane-type 4 matrix metalloproteinase (MT4-MMP) modulates water homeostasis in mice. Plos One. 6: e17099. PMID 21347258 DOI: 10.1371/Journal.Pone.0017099 | 0.32 | |||
| 2011 | Pozzi A, Zent R. TGF-β sequestration by mesangial cell integrin αvβ8: A novel mechanism of glomerular endothelial cell regulation. The American Journal of Pathology. 178: 485-9. PMID 21281780 DOI: 10.1016/J.Ajpath.2010.10.038 | 0.395 | |||
| 2011 | Kang L, Ayala JE, Lee-Young RS, Zhang Z, James FD, Neufer PD, Pozzi A, Zutter MM, Wasserman DH. Diet-induced muscle insulin resistance is associated with extracellular matrix remodeling and interaction with integrin alpha2beta1 in mice. Diabetes. 60: 416-26. PMID 21270253 DOI: 10.2337/Db10-1116 | 0.314 | |||
| 2011 | Pozzi A. Diseased renal glomeruli are getting soft. Focus on "Biophysical properties of normal and diseased renal glomeruli". American Journal of Physiology. Cell Physiology. 300: C394-6. PMID 21178112 DOI: 10.1152/Ajpcell.00511.2010 | 0.348 | |||
| 2011 | Xue Q, Gu C, Rivera J, Höök M, Chen X, Pozzi A, Xu Y. Entry of Bacillus anthracis spores into epithelial cells is mediated by the spore surface protein BclA, integrin α2β1 and complement component C1q. Cellular Microbiology. 13: 620-34. PMID 21134100 DOI: 10.1111/J.1462-5822.2010.01558.X | 0.41 | |||
| 2010 | Borza CM, Chen X, Mathew S, Mont S, Sanders CR, Zent R, Pozzi A. Integrin {alpha}1{beta}1 promotes caveolin-1 dephosphorylation by activating T cell protein-tyrosine phosphatase. The Journal of Biological Chemistry. 285: 40114-24. PMID 20940300 DOI: 10.1074/Jbc.M110.156729 | 0.425 | |||
| 2010 | Smeeton J, Zhang X, Bulus N, Mernaugh G, Lange A, Karner CM, Carroll TJ, Fässler R, Pozzi A, Rosenblum ND, Zent R. Integrin-linked kinase regulates p38 MAPK-dependent cell cycle arrest in ureteric bud development. Development (Cambridge, England). 137: 3233-43. PMID 20823064 DOI: 10.1242/Jcs.080705 | 0.35 | |||
| 2010 | Riggins KS, Mernaugh G, Su Y, Quaranta V, Koshikawa N, Seiki M, Pozzi A, Zent R. MT1-MMP-mediated basement membrane remodeling modulates renal development. Experimental Cell Research. 316: 2993-3005. PMID 20727881 DOI: 10.1016/J.Yexcr.2010.08.003 | 0.343 | |||
| 2010 | Gewin L, Bulus N, Mernaugh G, Moeckel G, Harris RC, Moses HL, Pozzi A, Zent R. TGF-beta receptor deletion in the renal collecting system exacerbates fibrosis. Journal of the American Society of Nephrology : Jasn. 21: 1334-43. PMID 20576806 DOI: 10.1681/Asn.2010020147 | 0.345 | |||
| 2010 | Chen X, Whiting C, Borza C, Hu W, Mont S, Bulus N, Zhang MZ, Harris RC, Zent R, Pozzi A. Integrin alpha1beta1 regulates epidermal growth factor receptor activation by controlling peroxisome proliferator-activated receptor gamma-dependent caveolin-1 expression. Molecular and Cellular Biology. 30: 3048-58. PMID 20368353 DOI: 10.1128/Mcb.00892-09 | 0.424 | |||
| 2010 | Pozzi A, Popescu V, Yang S, Mei S, Shi M, Puolitaival SM, Caprioli RM, Capdevila JH. The anti-tumorigenic properties of peroxisomal proliferator-activated receptor alpha are arachidonic acid epoxygenase-mediated. The Journal of Biological Chemistry. 285: 12840-50. PMID 20178979 DOI: 10.1074/Jbc.M109.081554 | 0.432 | |||
| 2010 | Pozzi A, Zent R. ZO-1 and ZONAB interact to regulate proximal tubular cell differentiation. Journal of the American Society of Nephrology : Jasn. 21: 388-90. PMID 20133486 DOI: 10.1681/Asn.2010010061 | 0.431 | |||
| 2009 | Pozzi A, Zent R. Regulation of endothelial cell functions by basement membrane- and arachidonic acid-derived products. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 1: 254-72. PMID 20835995 DOI: 10.1002/Wsbm.7 | 0.395 | |||
| 2009 | Nyström A, Shaik ZP, Gullberg D, Krieg T, Eckes B, Zent R, Pozzi A, Iozzo RV. Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity. Blood. 114: 4897-906. PMID 19789387 DOI: 10.1182/Blood-2009-02-207134 | 0.465 | |||
| 2009 | Zhang X, Mernaugh G, Yang DH, Gewin L, Srichai MB, Harris RC, Iturregui JM, Nelson RD, Kohan DE, Abrahamson D, Fässler R, Yurchenco P, Pozzi A, Zent R. beta1 integrin is necessary for ureteric bud branching morphogenesis and maintenance of collecting duct structural integrity. Development (Cambridge, England). 136: 3357-66. PMID 19710172 DOI: 10.1242/Dev.036269 | 0.392 | |||
| 2009 | Pozzi A, Zent R, Chetyrkin S, Borza C, Bulus N, Chuang P, Chen D, Hudson B, Voziyan P. Modification of collagen IV by glucose or methylglyoxal alters distinct mesangial cell functions. Journal of the American Society of Nephrology : Jasn. 20: 2119-25. PMID 19608705 DOI: 10.1681/Asn.2008080900 | 0.401 | |||
| 2009 | Red Brewer M, Choi SH, Alvarado D, Moravcevic K, Pozzi A, Lemmon MA, Carpenter G. The juxtamembrane region of the EGF receptor functions as an activation domain. Molecular Cell. 34: 641-51. PMID 19560417 DOI: 10.1016/J.Molcel.2009.04.034 | 0.323 | |||
| 2009 | Yang S, Wei S, Pozzi A, Capdevila JH. The arachidonic acid epoxygenase is a component of the signaling mechanisms responsible for VEGF-stimulated angiogenesis. Archives of Biochemistry and Biophysics. 489: 82-91. PMID 19464254 DOI: 10.1016/J.Abb.2009.05.006 | 0.399 | |||
| 2009 | Crooke CE, Pozzi A, Carpenter GF. PLC-gamma1 regulates fibronectin assembly and cell aggregation. Experimental Cell Research. 315: 2207-14. PMID 19379731 DOI: 10.1016/J.Yexcr.2009.04.008 | 0.386 | |||
| 2009 | Pozzi A, Voziyan PA, Hudson BG, Zent R. Regulation of matrix synthesis, remodeling and accumulation in glomerulosclerosis. Current Pharmaceutical Design. 15: 1318-33. PMID 19355971 DOI: 10.2174/138161209787846748 | 0.331 | |||
| 2009 | Zhang MZ, Xu J, Yao B, Yin H, Cai Q, Shrubsole MJ, Chen X, Kon V, Zheng W, Pozzi A, Harris RC. Inhibition of 11beta-hydroxysteroid dehydrogenase type II selectively blocks the tumor COX-2 pathway and suppresses colon carcinogenesis in mice and humans. The Journal of Clinical Investigation. 119: 876-85. PMID 19307727 DOI: 10.1172/Jci37398 | 0.38 | |||
| 2009 | Smith JP, Pozzi A, Dhawan P, Singh AB, Harris RC. Soluble HB-EGF induces epithelial-to-mesenchymal transition in inner medullary collecting duct cells by upregulating Snail-2. American Journal of Physiology. Renal Physiology. 296: F957-65. PMID 19244405 DOI: 10.1152/Ajprenal.90490.2008 | 0.411 | |||
| 2009 | Antar AA, Konopka JL, Campbell JA, Henry RA, Perdigoto AL, Carter BD, Pozzi A, Abel TW, Dermody TS. Junctional adhesion molecule-A is required for hematogenous dissemination of reovirus. Cell Host & Microbe. 5: 59-71. PMID 19154988 DOI: 10.1016/J.Chom.2008.12.001 | 0.359 | |||
| 2009 | Wang SE, Xiang B, Zent R, Quaranta V, Pozzi A, Arteaga CL. Transforming growth factor beta induces clustering of HER2 and integrins by activating Src-focal adhesion kinase and receptor association to the cytoskeleton. Cancer Research. 69: 475-82. PMID 19147560 DOI: 10.1158/0008-5472.Can-08-2649 | 0.393 | |||
| 2008 | Pyle AL, Atkinson JB, Pozzi A, Reese J, Eckes B, Davidson JM, Crimmins DL, Young PP. Regulation of the atheroma-enriched protein, SPRR3, in vascular smooth muscle cells through cyclic strain is dependent on integrin alpha1beta1/collagen interaction. The American Journal of Pathology. 173: 1577-88. PMID 18832573 DOI: 10.2353/Ajpath.2008.080042 | 0.39 | |||
| 2008 | Abair TD, Sundaramoorthy M, Chen D, Heino J, Ivaska J, Hudson BG, Sanders CR, Pozzi A, Zent R. Cross-talk between integrins alpha1beta1 and alpha2beta1 in renal epithelial cells. Experimental Cell Research. 314: 3593-604. PMID 18809396 DOI: 10.1016/J.Yexcr.2008.08.014 | 0.384 | |||
| 2008 | Pozzi A, Capdevila JH. PPARalpha Ligands as Antitumorigenic and Antiangiogenic Agents. Ppar Research. 2008: 906542. PMID 18725983 DOI: 10.1155/2008/906542 | 0.404 | |||
| 2008 | Macias-Perez I, Borza C, Chen X, Yan X, Ibanez R, Mernaugh G, Matrisian LM, Zent R, Pozzi A. Loss of integrin alpha1beta1 ameliorates Kras-induced lung cancer. Cancer Research. 68: 6127-35. PMID 18676835 DOI: 10.1158/0008-5472.Can-08-1395 | 0.77 | |||
| 2008 | Abair TD, Bulus N, Borza C, Sundaramoorthy M, Zent R, Pozzi A. Functional analysis of the cytoplasmic domain of the integrin {alpha}1 subunit in endothelial cells. Blood. 112: 3242-54. PMID 18647959 DOI: 10.1182/Blood-2007-12-126433 | 0.431 | |||
| 2008 | Taylor JL, Bielefeldt-Ohmann H, Pozzi A, Izzo AA. Lack of alpha-1 integrin alters lesion morphology during pulmonary Mycobacterium tuberculosis infection. Tuberculosis (Edinburgh, Scotland). 88: 444-52. PMID 18639492 DOI: 10.1016/J.Tube.2008.05.006 | 0.324 | |||
| 2008 | Pozzi A, Zent R. Integrins, extracellular matrix, and terminal differentiation of renal epithelial cells. Journal of the American Society of Nephrology : Jasn. 19: 1043-4. PMID 18480310 DOI: 10.1681/Asn.2008040370 | 0.399 | |||
| 2008 | Pozzi A, Jarad G, Moeckel GW, Coffa S, Zhang X, Gewin L, Eremina V, Hudson BG, Borza DB, Harris RC, Holzman LB, Phillips CL, Fassler R, Quaggin SE, Miner JH, et al. Beta1 integrin expression by podocytes is required to maintain glomerular structural integrity. Developmental Biology. 316: 288-301. PMID 18328474 DOI: 10.1016/J.Ydbio.2008.01.022 | 0.361 | |||
| 2008 | Cosgrove D, Meehan DT, Delimont D, Pozzi A, Chen X, Rodgers KD, Tempero RM, Zallocchi M, Rao VH. Integrin alpha1beta1 regulates matrix metalloproteinases via P38 mitogen-activated protein kinase in mesangial cells: implications for Alport syndrome. The American Journal of Pathology. 172: 761-73. PMID 18258846 DOI: 10.2353/Ajpath.2008.070473 | 0.411 | |||
| 2008 | Borza CM, Borza DB, Pedchenko V, Saleem MA, Mathieson PW, Sado Y, Hudson HM, Pozzi A, Saus J, Abrahamson DR, Zent R, Hudson BG. Human podocytes adhere to the KRGDS motif of the alpha3alpha4alpha5 collagen IV network. Journal of the American Society of Nephrology : Jasn. 19: 677-84. PMID 18235087 DOI: 10.1681/Asn.2007070793 | 0.321 | |||
| 2008 | Macias-Perez IM, Zent R, Carmosino M, Breyer MD, Breyer RM, Pozzi A. Mouse EP3 alpha, beta, and gamma receptor variants reduce tumor cell proliferation and tumorigenesis in vivo. The Journal of Biological Chemistry. 283: 12538-45. PMID 18230618 DOI: 10.1074/Jbc.M800105200 | 0.772 | |||
| 2008 | Zhang Z, Ramirez NE, Yankeelov TE, Li Z, Ford LE, Qi Y, Pozzi A, Zutter MM. alpha2beta1 integrin expression in the tumor microenvironment enhances tumor angiogenesis in a tumor cell-specific manner. Blood. 111: 1980-8. PMID 18042800 DOI: 10.1182/Blood-2007-06-094680 | 0.448 | |||
| 2008 | Woodall BP, Nyström A, Iozzo RA, Eble JA, Niland S, Krieg T, Eckes B, Pozzi A, Iozzo RV. Integrin α2β1 is the required receptor for endorepellin angiostatic activity Journal of Biological Chemistry. 283: 2335-2343. PMID 18024432 DOI: 10.1074/Jbc.M708364200 | 0.446 | |||
| 2008 | Nystrom A, Shaik ZP, Pozzi A, Krieg T, Eckes B, Iozzo RV. Endorepellin evokes SHP1 activity in endothelial cells Matrix Biology. 27: 11-12. DOI: 10.1016/J.Matbio.2008.09.226 | 0.369 | |||
| 2007 | Zhang H, Lawson WE, Polosukhin VV, Pozzi A, Blackwell TS, Litingtung Y, Chiang C. Inhibitor of differentiation 1 promotes endothelial survival in a bleomycin model of lung injury in mice. The American Journal of Pathology. 171: 1113-26. PMID 17717145 DOI: 10.2353/Ajpath.2007.070226 | 0.364 | |||
| 2007 | Erdogan M, Pozzi A, Bhowmick N, Moses HL, Zent R. Signaling pathways regulating TC21-induced tumorigenesis. The Journal of Biological Chemistry. 282: 27713-20. PMID 17656362 DOI: 10.1074/Jbc.M703037200 | 0.384 | |||
| 2007 | Kanjanabuch T, Ma LJ, Chen J, Pozzi A, Guan Y, Mundel P, Fogo AB. PPAR-γ agonist protects podocytes from injury Kidney International. 71: 1232-1239. PMID 17457378 DOI: 10.1038/Sj.Ki.5002248 | 0.359 | |||
| 2007 | Pozzi A, Ibanez MR, Gatica AE, Yang S, Wei S, Mei S, Falck JR, Capdevila JH. Peroxisomal proliferator-activated receptor-alpha-dependent inhibition of endothelial cell proliferation and tumorigenesis. The Journal of Biological Chemistry. 282: 17685-95. PMID 17405874 DOI: 10.1074/Jbc.M701429200 | 0.479 | |||
| 2007 | Rao R, Redha R, Macias-Perez I, Su Y, Hao C, Zent R, Breyer MD, Pozzi A. Prostaglandin E2-EP4 receptor promotes endothelial cell migration via ERK activation and angiogenesis in vivo. The Journal of Biological Chemistry. 282: 16959-68. PMID 17401137 DOI: 10.1074/Jbc.M701214200 | 0.777 | |||
| 2007 | Chen X, Abair TD, Ibanez MR, Su Y, Frey MR, Dise RS, Polk DB, Singh AB, Harris RC, Zent R, Pozzi A. Integrin alpha1beta1 controls reactive oxygen species synthesis by negatively regulating epidermal growth factor receptor-mediated Rac activation. Molecular and Cellular Biology. 27: 3313-26. PMID 17339338 DOI: 10.1128/Mcb.01476-06 | 0.447 | |||
| 2007 | Zweers MC, Davidson JM, Pozzi A, Hallinger R, Janz K, Quondamatteo F, Leutgeb B, Krieg T, Eckes B. Integrin alpha2beta1 is required for regulation of murine wound angiogenesis but is dispensable for reepithelialization. The Journal of Investigative Dermatology. 127: 467-78. PMID 16977325 DOI: 10.1038/Sj.Jid.5700546 | 0.397 | |||
| 2007 | Zutter MM, Zhang Z, Ramirez NE, Pozzi A. The role of the α2β1 integrin in the tumor microenvironment The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A205-A | 0.313 | |||
| 2006 | Muñoz NM, Upton M, Rojas A, Washington MK, Lin L, Chytil A, Sozmen EG, Madison BB, Pozzi A, Moon RT, Moses HL, Grady WM. Transforming growth factor beta receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation. Cancer Research. 66: 9837-44. PMID 17047044 DOI: 10.1158/0008-5472.Can-06-0890 | 0.385 | |||
| 2006 | Acuff HB, Sinnamon M, Fingleton B, Boone B, Levy SE, Chen X, Pozzi A, Carbone DP, Schwartz DR, Moin K, Sloane BF, Matrisian LM. Analysis of host- and tumor-derived proteinases using a custom dual species microarray reveals a protective role for stromal matrix metalloproteinase-12 in non-small cell lung cancer. Cancer Research. 66: 7968-75. PMID 16912171 DOI: 10.1158/0008-5472.Can-05-4279 | 0.36 | |||
| 2006 | Liang XB, Ma LJ, Naito T, Wang Y, Madaio M, Zent R, Pozzi A, Fogo AB. Angiotensin type 1 receptor blocker restores podocyte potential to promote glomerular endothelial cell growth. Journal of the American Society of Nephrology : Jasn. 17: 1886-95. PMID 16790514 DOI: 10.1681/Asn.2005020205 | 0.435 | |||
| 2006 | Zent R, Yan X, Su Y, Hudson BG, Borza DB, Moeckel GW, Qi Z, Sado Y, Breyer MD, Voziyan P, Pozzi A. Glomerular injury is exacerbated in diabetic integrin alpha1-null mice. Kidney International. 70: 460-70. PMID 16775606 DOI: 10.1038/Sj.Ki.5000359 | 0.351 | |||
| 2006 | Kamiyama M, Pozzi A, Yang L, DeBusk LM, Breyer RM, Lin PC. EP2, a receptor for PGE2, regulates tumor angiogenesis through direct effects on endothelial cell motility and survival. Oncogene. 25: 7019-7028. PMID 16732324 DOI: 10.1038/Sj.Onc.1209694 | 0.48 | |||
| 2006 | Borza CM, Pozzi A, Borza DB, Pedchenko V, Hellmark T, Hudson BG, Zent R. Integrin alpha3beta1, a novel receptor for alpha3(IV) noncollagenous domain and a trans-dominant Inhibitor for integrin alphavbeta3. The Journal of Biological Chemistry. 281: 20932-9. PMID 16731529 DOI: 10.1074/Jbc.M601147200 | 0.42 | |||
| 2006 | Moeckel GW, Zhang L, Chen X, Rossini M, Zent R, Pozzi A. Role of integrin alpha1beta1 in the regulation of renal medullary osmolyte concentration. American Journal of Physiology. Renal Physiology. 290: F223-31. PMID 16106035 DOI: 10.1152/Ajprenal.00371.2004 | 0.466 | |||
| 2006 | Maciasperez I, Chen X, Yan X, Ibanez R, Zent R, Pozzi A. Integrin alpha1beta1 contributes to NSCLC progression Matrix Biology. 25. DOI: 10.1016/J.Matbio.2006.08.149 | 0.302 | |||
| 2006 | Chen X, Ibanez R, Su Y, Pozo MAD, Zent R, Pozzi A. Integrin α1β1 regulates EGFR activation Matrix Biology. 25. DOI: 10.1016/J.Matbio.2006.08.015 | 0.319 | |||
| 2005 | Frank DB, Abtahi A, Yamaguchi DJ, Manning S, Shyr Y, Pozzi A, Baldwin HS, Johnson JE, de Caestecker MP. Bone morphogenetic protein 4 promotes pulmonary vascular remodeling in hypoxic pulmonary hypertension. Circulation Research. 97: 496-504. PMID 16100039 DOI: 10.1161/01.Res.0000181152.65534.07 | 0.364 | |||
| 2005 | Chen X, Su Y, Fingleton B, Acuff H, Matrisian LM, Zent R, Pozzi A. An orthotopic model of lung cancer to analyze primary and metastatic NSCLC growth in integrin alpha1-null mice. Clinical & Experimental Metastasis. 22: 185-93. PMID 16086239 DOI: 10.1007/S10585-005-7453-8 | 0.413 | |||
| 2005 | Brábek J, Constancio SS, Siesser PF, Shin NY, Pozzi A, Hanks SK. Crk-associated substrate tyrosine phosphorylation sites are critical for invasion and metastasis of SRC-transformed cells. Molecular Cancer Research : McR. 3: 307-15. PMID 15972849 DOI: 10.1158/1541-7786.Mcr-05-0015 | 0.334 | |||
| 2005 | Pozzi A, Macias-Perez I, Abair T, Wei S, Su Y, Zent R, Falck JR, Capdevila JH. Characterization of 5,6- and 8,9-epoxyeicosatrienoic acids (5,6- and 8,9-EET) as potent in vivo angiogenic lipids. The Journal of Biological Chemistry. 280: 27138-46. PMID 15917237 DOI: 10.1074/Jbc.M501730200 | 0.771 | |||
| 2005 | Thomas EK, Nakamura M, Wienke D, Isacke CM, Pozzi A, Liang P. Endo180 binds to the C-terminal region of type I collagen. The Journal of Biological Chemistry. 280: 22596-605. PMID 15817460 DOI: 10.1074/Jbc.M501155200 | 0.385 | |||
| 2005 | Chen X, Su Y, Fingleton B, Acuff H, Matrisian LM, Zent R, Pozzi A. Increased plasma MMP9 in integrin alpha1-null mice enhances lung metastasis of colon carcinoma cells. International Journal of Cancer. 116: 52-61. PMID 15756690 DOI: 10.1002/Ijc.20997 | 0.396 | |||
| 2005 | Cai S, Bulus N, Fonseca-Siesser PM, Chen D, Hanks SK, Pozzi A, Zent R. CD98 modulates integrin beta1 function in polarized epithelial cells. Journal of Cell Science. 118: 889-99. PMID 15713750 DOI: 10.1242/Jcs.01674 | 0.33 | |||
| 2004 | Chen X, Moeckel G, Morrow JD, Cosgrove D, Harris RC, Fogo AB, Zent R, Pozzi A. Lack of integrin alpha1beta1 leads to severe glomerulosclerosis after glomerular injury. The American Journal of Pathology. 165: 617-30. PMID 15277235 DOI: 10.1016/S0002-9440(10)63326-3 | 0.403 | |||
| 2004 | Brábek J, Constancio SS, Shin NY, Pozzi A, Weaver AM, Hanks SK. CAS promotes invasiveness of Src-transformed cells. Oncogene. 23: 7406-15. PMID 15273716 DOI: 10.1038/Sj.Onc.1207965 | 0.326 | |||
| 2004 | Chen D, Roberts R, Pohl M, Nigam S, Kreidberg J, Wang Z, Heino J, Ivaska J, Coffa S, Harris RC, Pozzi A, Zent R. Differential expression of collagen- and laminin-binding integrins mediates ureteric bud and inner medullary collecting duct cell tubulogenesis American Journal of Physiology - Renal Physiology. 287: F602-F611. PMID 15187002 DOI: 10.1152/Ajprenal.00015.2004 | 0.422 | |||
| 2004 | Pozzi A, Yan X, Macias-Perez I, Wei S, Hata AN, Breyer RM, Morrow JD, Capdevila JH. Colon carcinoma cell growth is associated with prostaglandin E2/EP4 receptor-evoked ERK activation. The Journal of Biological Chemistry. 279: 29797-804. PMID 15123663 DOI: 10.1074/Jbc.M313989200 | 0.774 | |||
| 2004 | Brantley-Sieders DM, Caughron J, Hicks D, Pozzi A, Ruiz JC, Chen J. EphA2 receptor tyrosine kinase regulates endothelial cell migration and vascular assembly through phosphoinositide 3-kinase-mediated Rac1 GTPase activation Journal of Cell Science. 117: 2037-2049. PMID 15054110 DOI: 10.1242/Jcs.01061 | 0.446 | |||
| 2004 | Pozzi A, Zent R. Integrins: sensors of extracellular matrix and modulators of cell function. Nephron Experimental Nephrology. 94. PMID 12902617 DOI: 10.1159/000072025 | 0.351 | |||
| 2003 | Moeckel GW, Zhang L, Fogo AB, Hao CM, Pozzi A, Breyer MD. COX2 activity promotes organic osmolyte accumulation and adaptation of renal medullary interstitial cells to hypertonic stress. The Journal of Biological Chemistry. 278: 19352-7. PMID 12637551 DOI: 10.1074/Jbc.M302209200 | 0.388 | |||
| 2002 | Brantley DM, Cheng N, Thompson EJ, Lin Q, Brekken RA, Thorpe PE, Muraoka RS, Cerretti DP, Pozzi A, Jackson D, Lin C, Chen J. Soluble Eph A receptors inhibit tumor angiogenesis and progression in vivo. Oncogene. 21: 7011-26. PMID 12370823 DOI: 10.1038/Sj.Onc.1205679 | 0.434 | |||
| 2002 | Pozzi A, LeVine WF, Gardner HA. Low plasma levels of matrix metalloproteinase 9 permit increased tumor angiogenesis. Oncogene. 21: 272-81. PMID 11803470 DOI: 10.1038/Sj.Onc.1205045 | 0.405 | |||
| 2000 | Pozzi A, Moberg PE, Miles LA, Wagner S, Soloway P, Gardner HA. Elevated matrix metalloprotease and angiostatin levels in integrin alpha 1 knockout mice cause reduced tumor vascularization. Proceedings of the National Academy of Sciences of the United States of America. 97: 2202-7. PMID 10681423 DOI: 10.1073/Pnas.040378497 | 0.444 | |||
| 1999 | Giannelli G, Pozzi A, Stetler-Stevenson WG, Gardner HA, Quaranta V. Expression of matrix metalloprotease-2-cleaved laminin-5 in breast remodeling stimulated by sex steroids. The American Journal of Pathology. 154: 1193-201. PMID 10233857 DOI: 10.1016/S0002-9440(10)65371-0 | 0.313 | |||
| 1998 | Pozzi A, Wary KK, Giancotti FG, Gardner HA. Integrin alpha1beta1 mediates a unique collagen-dependent proliferation pathway in vivo. The Journal of Cell Biology. 142: 587-94. PMID 9679154 DOI: 10.1083/Jcb.142.2.587 | 0.45 | |||
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