Joseph Duffy

Affiliations: 
University of Florida, Gainesville, Gainesville, FL, United States 
Area:
Mechanical Engineering, Computer Science
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"Joseph Duffy"
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Publications

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Yu W, Liu J, Clausen D, et al. (2021) Discovery of Ethyl Ketone-Based Highly Selective HDACs 1, 2, 3 Inhibitors for HIV Latency Reactivation with Minimum Cellular Potency Serum Shift and Reduced hERG Activity. Journal of Medicinal Chemistry
Meng N, Yu W, Suzuki T, et al. (2021) Mild Condition for the Deoxygenation of α-Heteroaryl-Substituted Methanol Derivatives. The Journal of Organic Chemistry
Liu J, Yu Y, Kelly J, et al. (2020) Discovery of Highly Selective and Potent HDAC3 Inhibitors Based on a 2-Substituted Benzamide Zinc Binding Group. Acs Medicinal Chemistry Letters. 11: 2476-2483
Clausen DJ, Liu J, Yu W, et al. (2020) Development of a selective HDAC inhibitor aimed at reactivating the HIV latent reservoir. Bioorganic & Medicinal Chemistry Letters. 30: 127367
Liu J, Guiadeen D, Krikorian A, et al. (2020) Potent, non-covalent reversible BTK inhibitors with 8-amino-imidazo[1,5-a]pyrazine core featuring 3-position bicyclic ring substitutes. Bioorganic & Medicinal Chemistry Letters. 30: 127390
Liu J, Kelly J, Yu W, et al. (2020) Selective Class I HDAC Inhibitors Based on Aryl Ketone Zinc Binding Induce HIV-1 Protein for Clearance. Acs Medicinal Chemistry Letters. 11: 1476-1483
Lei Z, Bao J, Cheng C, et al. (2020) Selective N7 Alkylation of 7-Azaindazoles. The Journal of Organic Chemistry
Yu W, Liu J, Yu Y, et al. (2020) Discovery of ethyl ketone-based HDACs 1, 2, and 3 selective inhibitors for HIV latency reactivation. Bioorganic & Medicinal Chemistry Letters. 127197
Liu W, Hussain Z, Zang Y, et al. (2018) Optimization of Preclinical Metabolism for Somatostatin Receptor Subtype 5-Selective Antagonists. Acs Medicinal Chemistry Letters. 9: 1088-1093
Josephs KA, Whitwell JL, Tacik P, et al. (2016) [18F]AV-1451 tau-PET uptake does correlate with quantitatively measured 4R-tau burden in autopsy-confirmed corticobasal degeneration. Acta Neuropathologica
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