Lucas D. Ward

Affiliations: 
2000-2004 University of Virginia, Charlottesville, VA 
 2004-2010 Columbia University, New York, NY 
 2010-2014 Massachusetts Institute of Technology, Cambridge, MA, United States 
 2015-2019 Amgen Inc., Thousand Oaks, CA, United States 
 2016-2016 deCode Genetics Inc 
 2019- Alnylam Pharmaceuticals 
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"Lucas D. Ward"

Parents

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Joel G. Belasco research assistant 2003 (Microtree)
Anne Beyer research assistant 2002-2003 UVA (Neurotree)
Virginia W. Cornish research assistant 2004 (Chemistry Tree)
Iva Susan Greenwald research assistant 2005 (GenetiTree)
Harmen J. Bussemaker grad student 2010 Columbia (Physics Tree)
Manolis Kellis post-doc 2010-2014 MIT
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Publications

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Hoffing RA, Deaton AM, Holleman AM, et al. (2024) Transcript-aware analysis of rare predicted loss-of-function variants in the UK Biobank elucidate new isoform-trait associations. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 29: 247-260
Sun BB, Chiou J, Traylor M, et al. (2023) Plasma proteomic associations with genetics and health in the UK Biobank. Nature. 622: 329-338
Carss KJ, Deaton AM, Del Rio-Espinola A, et al. (2022) Using human genetics to improve safety assessment of therapeutics. Nature Reviews. Drug Discovery
Nguyen PA, Born DA, Deaton AM, et al. (2019) Phenotypes associated with genes encoding drug targets are predictive of clinical trial side effects. Nature Communications. 10: 1579
Fielden MR, Ward LD, Minocherhomji S, et al. (2017) Modernizing Human Cancer Risk Assessment of Therapeutics. Trends in Pharmacological Sciences
Jónsson H, Sulem P, Kehr B, et al. (2017) Parental influence on human germline de novo mutations in 1,548 trios from Iceland. Nature. 549: 519-522
Jónsson H, Sulem P, Kehr B, et al. (2017) Whole genome characterization of sequence diversity of 15,220 Icelanders. Scientific Data. 4: 170115
Benonisdottir S, Oddsson A, Helgason A, et al. (2016) Epigenetic and genetic components of height regulation. Nature Communications. 7: 13490
Ward LD, Kellis M. (2016) HaploReg v4: systematic mining of putative causal variants, cell types, regulators and target genes for human complex traits and disease. Nucleic Acids Research. 44: D877-81
Onengut-Gumuscu S, Chen WM, Burren O, et al. (2015) Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers. Nature Genetics. 47: 381-6
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