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Alexander M Xu

Affiliations: 
Institute for Systems Biology, Seattle, WA, United States 
Area:
Single Cell Analysis, Nanotechnology, Drug Delivery, Transcriptomics, Sequencing
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Nicholas  A. Melosh grad student 2010-2015 Stanford
James Richard Heath post-doc 2015- Caltech

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Chour W, Choi J, Xie J, et al. (2023) Large libraries of single-chain trimer peptide-MHCs enable antigen-specific CD8+ T cell discovery and analysis. Communications Biology. 6: 528
Xu AM, Chour W, DeLucia DC, et al. (2023) Entropic analysis of antigen-specific CDR3 domains identifies essential binding motifs shared by CDR3s with different antigen specificities. Cell Systems
Heath J, Chour W, Choi J, et al. (2022) Large libraries of single-chain trimer peptide-MHCs enable rapid antigen-specific CD8+ T cell discovery and analysis. Research Square
Su Y, Ko ME, Cheng H, et al. (2020) Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line. Nature Communications. 11: 2345
He G, Hu N, Xu AM, et al. (2020) Nanoneedle Platforms: The Many Ways to Pierce the Cell Membrane Advanced Functional Materials. 30: 1909890
Ng AHC, Peng S, Xu AM, et al. (2019) MATE-Seq: microfluidic antigen-TCR engagement sequencing. Lab On a Chip. 19: 3011-3021
Peng S, Zaretsky JM, Ng AHC, et al. (2019) Sensitive Detection and Analysis of Neoantigen-Specific T Cell Populations from Tumors and Blood. Cell Reports. 28: 2728-2738.e7
Xu AM, Liu Q, Takata KL, et al. (2018) Integrated measurement of intracellular proteins and transcripts in single cells. Lab On a Chip
Sander J, Schmidt SV, Cirovic B, et al. (2017) Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2. Immunity. 47: 1051-1066.e12
Xu AM, Wang DS, Shieh P, et al. (2017) Direct Intracellular Delivery of Cell Impermeable Probes of Protein Glycosylation Using Nanostraws. Chembiochem : a European Journal of Chemical Biology
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