Jacques Genest - Publications

Affiliations: 
Université de Montréal, Montréal, Canada 
Area:
Animal Physiology Biology, Biochemistry
Website:
https://www.mcgill.ca/expmed/dr-jacques-genest

130 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Bélanger AM, Akioyamen L, Alothman L, Genest J. Evidence for improved survival with treatment of homozygous familial hypercholesterolemia. Current Opinion in Lipidology. PMID 32520777 DOI: 10.1097/Mol.0000000000000686  0.328
2018 Schwertani A, Choi HY, Genest J. HDLs and the pathogenesis of atherosclerosis. Current Opinion in Cardiology. PMID 29561322 DOI: 10.1097/Hco.0000000000000508  0.368
2017 Choi HY, Ruel I, Malina A, Garrod DR, Oda MN, Pelletier J, Schwertani A, Genest J. Desmocollin 1 is abundantly expressed in atherosclerosis and impairs high-density lipoprotein biogenesis. European Heart Journal. PMID 29106519 DOI: 10.1016/J.Atherosclerosissup.2018.04.080  0.361
2015 Hafiane A, Bielicki JK, Johansson JO, Genest J. Novel Apo E-Derived ABCA1 Agonist Peptide (CS-6253) Promotes Reverse Cholesterol Transport and Induces Formation of preβ-1 HDL In Vitro. Plos One. 10: e0131997. PMID 26207756 DOI: 10.1371/journal.pone.0131997  0.311
2014 Iatan I, Choi HY, Ruel I, Reddy MV, Kil H, Lee J, Odeh MA, Salah Z, Abu-Remaileh M, Weissglas-Volkov D, Nikkola E, Civelek M, Awan Z, Croce CM, Aqeilan RI, ... ... Genest J, et al. The WWOX gene modulates high-density lipoprotein and lipid metabolism. Circulation. Cardiovascular Genetics. 7: 491-504. PMID 24871327 DOI: 10.1161/Circgenetics.113.000248  0.352
2012 Reddy MV, Iatan I, Weissglas-Volkov D, Nikkola E, Haas BE, Juvonen M, Ruel I, Ruel MJ, Sinsheimer JS, Genest J, Pajukanta P. Exome sequencing identifies 2 rare variants for low high-density lipoprotein cholesterol in an extended family. Circulation. Cardiovascular Genetics. 5: 538-46. PMID 22923419 DOI: 10.1161/Circgenetics.112.963264  0.319
2012 You Z, Genest J, Barrette PO, Hafiane A, Behm DJ, D'Orleans-Juste P, Schwertani AG. Genetic and pharmacological manipulation of urotensin II ameliorate the metabolic and atherosclerosis sequalae in mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1809-16. PMID 22723440 DOI: 10.1161/Atvbaha.112.252973  0.308
2011 Iatan I, Bailey D, Ruel I, Hafiane A, Campbell S, Krimbou L, Genest J. Membrane microdomains modulate oligomeric ABCA1 function: impact on apoAI-mediated lipid removal and phosphatidylcholine biosynthesis. Journal of Lipid Research. 52: 2043-55. PMID 21846716 DOI: 10.1194/Jlr.M016196  0.363
2010 Bailey D, Ruel I, Hafiane A, Cochrane H, Iatan I, Jauhiainen M, Ehnholm C, Krimbou L, Genest J. Analysis of lipid transfer activity between model nascent HDL particles and plasma lipoproteins: implications for current concepts of nascent HDL maturation and genesis. Journal of Lipid Research. 51: 785-97. PMID 19797257 DOI: 10.1194/Jlr.M001875  0.422
2010 Dubuc G, Tremblay M, Paré G, Jacques H, Hamelin J, Benjannet S, Boulet L, Genest J, Bernier L, Seidah NG, Davignon J. A new method for measurement of total plasma PCSK9: clinical applications. Journal of Lipid Research. 51: 140-9. PMID 19571328 DOI: 10.1194/Jlr.M900273-Jlr200  0.379
2009 Iatan I, Dastani Z, Do R, Weissglas-Volkov D, Ruel I, Lee JC, Huertas-Vazquez A, Taskinen MR, Prat A, Seidah NG, Pajukanta P, Engert JC, Genest J. Genetic variation at the proprotein convertase subtilisin/kexin type 5 gene modulates high-density lipoprotein cholesterol levels. Circulation. Cardiovascular Genetics. 2: 467-75. PMID 20031622 DOI: 10.1161/Circgenetics.109.877811  0.39
2009 Abourbih S, Filion KB, Joseph L, Schiffrin EL, Rinfret S, Poirier P, Pilote L, Genest J, Eisenberg MJ. Effect of fibrates on lipid profiles and cardiovascular outcomes: a systematic review. The American Journal of Medicine. 122: 962.e1-8. PMID 19698935 DOI: 10.1016/J.Amjmed.2009.03.030  0.307
2009 Ridker PM, Danielson E, Fonseca FA, Genest J, Gotto AM, Kastelein JJ, Koenig W, Libby P, Lorenzatti AJ, MacFadyen JG, Nordestgaard BG, Shepherd J, Willerson JT, Glynn RJ. Reduction in C-Reactive Protein and Low-Density Lipoprotein Cholesterol and Cardiovascular Event Rates After Initiation of Rosuvastatin: A Prospective Study of the Justification for the Use of Statins in Prevention: An Intervention Trial Evaluating Rosuvastatin Trial Obstetrical & Gynecological Survey. 64: 596-597. DOI: 10.1097/01.Ogx.0000358018.78512.A1  0.316
2009 Gordon A, Jahagirdar R, Johansson J, Chiacchia F, Hansen H, Wagner G, Bailey D, Krimbou L, Genest J, Wong N. Abstract: 1453 RVX-208 A SMALL MOLECULE INCREASES APOA-I, PREB-HDL, AND FUNCTIONALITY OF HDL IN HUMANS Atherosclerosis Supplements. 10. DOI: 10.1016/S1567-5688(09)70184-9  0.32
2008 Genest J. The Yin and Yang of high-density lipoprotein cholesterol. Journal of the American College of Cardiology. 51: 643-4. PMID 18261683 DOI: 10.1016/J.Jacc.2007.10.033  0.358
2008 Hassan HH, Bailey D, Lee DY, Iatan I, Hafiane A, Ruel I, Krimbou L, Genest J. Quantitative analysis of ABCA1-dependent compartmentalization and trafficking of apolipoprotein A-I: implications for determining cellular kinetics of nascent high density lipoprotein biogenesis. The Journal of Biological Chemistry. 283: 11164-75. PMID 18218626 DOI: 10.1074/Jbc.M707720200  0.382
2008 Dubuc G, Tremblay M, Pare G, Jacques H, Boulet L, Genest J, Bernier L, Seidah N, Davignon J. STATINS AND EZETIMIBE UPREGULATE PLASMA PCSK9 Atherosclerosis Supplements. 9: 186. DOI: 10.1016/S1567-5688(08)70747-5  0.337
2008 Jahagirdar R, Genest J, Hansen HC, Nicholls CD, Attwell S, McLure KG, Wagner GS, Johansson J, Wong NC. Rvx-208: A Small Molecule That Increases Apoa-I, Hdl-C, And Cholesterol Efflux Atherosclerosis Supplements. 9: 2. DOI: 10.1016/S1567-5688(08)70007-2  0.34
2007 Hassan HH, Denis M, Lee DY, Iatan I, Nyholt D, Ruel I, Krimbou L, Genest J. Identification of an ABCA1-dependent phospholipid-rich plasma membrane apolipoprotein A-I binding site for nascent HDL formation: implications for current models of HDL biogenesis. Journal of Lipid Research. 48: 2428-42. PMID 17656736 DOI: 10.1194/Jlr.M700206-Jlr200  0.356
2006 Krimbou L, Marcil M, Genest J. New insights into the biogenesis of human high-density lipoproteins. Current Opinion in Lipidology. 17: 258-67. PMID 16680030 DOI: 10.1097/01.Mol.0000226117.43178.7C  0.361
2006 Mikael LG, Genest J, Rozen R. Elevated homocysteine reduces apolipoprotein A-I expression in hyperhomocysteinemic mice and in males with coronary artery disease. Circulation Research. 98: 564-71. PMID 16439690 DOI: 10.1161/01.Res.0000204825.66410.0B  0.37
2006 Ching YL, Lesimple A, Denis M, Vincent J, Larsen A, Mamer O, Krimbou L, Genest J, Marcil M. Increased sphingomyelin content impairs HDL biogenesis and maturation in human Niemann-Pick disease type B Journal of Lipid Research. 47: 622-632. PMID 16319418 DOI: 10.1194/Jlr.M500487-Jlr200  0.394
2006 Lee JL, Aouizerat B, Genest J, Taskinen MR, Pajukanta P. We-W44:5 A two step strategy to localize gene(s) influencing low high-density lipoprotein cholesterol level on chromosome 16Q23-24 Atherosclerosis Supplements. 7: 333. DOI: 10.1016/S1567-5688(06)81327-9  0.301
2005 Krimbou L, Hajj Hassan H, Blain S, Rashid S, Denis M, Marcil M, Genest J. Biogenesis and speciation of nascent apoA-I-containing particles in various cell lines. Journal of Lipid Research. 46: 1668-77. PMID 15897603 DOI: 10.1194/Jlr.M500038-Jlr200  0.728
2005 Ching YL, Lesimple A, Larsen A, Mamer O, Genest J. ESI-MS quantitation of increased sphingomyelin in Niemann-Pick disease type B HDL Journal of Lipid Research. 46: 1213-1228. PMID 15741650 DOI: 10.1194/Jlr.M500011-Jlr200  0.386
2005 Hajj Hassan H, Blain S, Boucher B, Denis M, Krimbou L, Genest J. Structural modification of plasma HDL by phospholipids promotes efficient ABCA1-mediated cholesterol release. Journal of Lipid Research. 46: 1457-65. PMID 15654121 DOI: 10.1194/Jlr.M400477-Jlr200  0.76
2004 Denis M, Haidar B, Marcil M, Bouvier M, Krimbou L, Genest J. Characterization of oligomeric human ATP binding cassette transporter A1. Potential implications for determining the structure of nascent high density lipoprotein particles. The Journal of Biological Chemistry. 279: 41529-36. PMID 15280376 DOI: 10.1074/Jbc.M406881200  0.775
2004 Marcil M, O'Connell B, Krimbou L, Genest J. High-density lipoproteins: multifunctional vanguards of the cardiovascular system. Expert Review of Cardiovascular Therapy. 2: 417-30. PMID 15151487 DOI: 10.1586/14779072.2.3.417  0.316
2004 Alenezi MY, Marcil M, Blank D, Sherman M, Genest J. Is the decreased high-density lipoprotein cholesterol in the metabolic syndrome due to cellular lipid efflux defect? The Journal of Clinical Endocrinology and Metabolism. 89: 761-4. PMID 14764793 DOI: 10.1210/Jc.2003-031213  0.364
2004 Krimbou L, Denis M, Haidar B, Carrier M, Marcil M, Genest J. Molecular interactions between apoE and ABCA1: impact on apoE lipidation. Journal of Lipid Research. 45: 839-48. PMID 14754908 DOI: 10.1194/Jlr.M300418-Jlr200  0.787
2004 Haidar B, Denis M, Marcil M, Krimbou L, Genest J. Apolipoprotein A-I activates cellular cAMP signaling through the ABCA1 transporter. The Journal of Biological Chemistry. 279: 9963-9. PMID 14701824 DOI: 10.1074/Jbc.M313487200  0.765
2004 Denis M, Haidar B, Marcil M, Bouvier M, Krimbou L, Genest J. Molecular and cellular physiology of apolipoprotein A-I lipidation by the ATP-binding cassette transporter A1 (ABCA1). The Journal of Biological Chemistry. 279: 7384-94. PMID 14660648 DOI: 10.1074/Jbc.M306963200  0.783
2003 Denis M, Bissonnette R, Haidar B, Krimbou L, Bouvier M, Genest J. Expression, regulation, and activity of ABCA1 in human cell lines. Molecular Genetics and Metabolism. 78: 265-74. PMID 12706378 DOI: 10.1016/S1096-7192(03)00020-9  0.769
2003 Krimbou L, Marcil M, Chiba H, Genest J. Structural and functional properties of human plasma high density-sized lipoprotein containing only apoE particles. Journal of Lipid Research. 44: 884-92. PMID 12611904 DOI: 10.1194/Jlr.M200273-Jlr200  0.429
2002 Sniderman AD, Zhang Z, Genest J, Cianflone K. Effects on apoB-100 secretion and bile acid synthesis by redirecting cholesterol efflux from HepG2 cells. Journal of Lipid Research. 44: 527-32. PMID 12562860 DOI: 10.1194/Jlr.M200187-Jlr200  0.4
2002 Haidar B, Denis M, Krimbou L, Marcil M, Genest J. cAMP induces ABCA1 phosphorylation activity and promotes cholesterol efflux from fibroblasts. Journal of Lipid Research. 43: 2087-94. PMID 12454270 DOI: 10.1194/Jlr.M200235-Jlr200  0.775
2001 O’Connell BJ, Genest J. High-Density Lipoproteins and Endothelial Function Circulation. 104: 1978-1983. PMID 11602504 DOI: 10.1161/Hc3901.096667  0.402
2001 McPherson R, Angus C, Murray P, Genest J. Efficacy of atorvastatin in achieving National Cholesterol Education Program low-density lipoprotein targets in women with severe dyslipidemia and cardiovascular disease or risk factors for cardiovascular disease: The Women's Atorvastatin Trial on Cholesterol (WATCH). American Heart Journal. 141: 949-56. PMID 11376309 DOI: 10.1067/Mhj.2001.115588  0.317
2001 Clee SM, Zwinderman AH, Engert JC, Zwarts KY, Molhuizen HO, Roomp K, Jukema JW, van Wijland M, van Dam M, Hudson TJ, Brooks-Wilson A, Genest J, Kastelein JJ, Hayden MR. Common genetic variation in ABCA1 is associated with altered lipoprotein levels and a modified risk for coronary artery disease. Circulation. 103: 1198-205. PMID 11238261 DOI: 10.1161/01.Cir.103.9.1198  0.37
2001 Haidar B, Mott S, Boucher B, Lee CY, Marcil M, Genest J. Cellular cholesterol efflux is modulated by phospholipid-derived signaling molecules in familial HDL deficiency/Tangier disease fibroblasts. Journal of Lipid Research. 42: 249-57. PMID 11181755  0.78
2000 Clee SM, Kastelein JJ, van Dam M, Marcil M, Roomp K, Zwarts KY, Collins JA, Roelants R, Tamasawa N, Stulc T, Suda T, Ceska R, Boucher B, Rondeau C, DeSouich C, ... ... Genest J, et al. Age and residual cholesterol efflux affect HDL cholesterol levels and coronary artery disease in ABCA1 heterozygotes. The Journal of Clinical Investigation. 106: 1263-70. PMID 11086027 DOI: 10.1172/Jci10727  0.366
2000 Hayden MR, Clee SM, Brooks-Wilson A, Genest J, Attie A, Kastelein JJ. Cholesterol efflux regulatory protein, Tangier disease and familial high-density lipoprotein deficiency. Current Opinion in Lipidology. 11: 117-22. PMID 10787172 DOI: 10.1097/00041433-200004000-00003  0.364
1999 Marcil M, Brooks-Wilson A, Clee SM, Roomp K, Zhang LH, Yu L, Collins JA, van Dam M, Molhuizen HO, Loubster O, Ouellette BF, Sensen CW, Fichter K, Mott S, Denis M, ... ... Genest J, et al. Mutations in the ABC1 gene in familial HDL deficiency with defective cholesterol efflux. Lancet. 354: 1341-6. PMID 10533863 DOI: 10.1016/S0140-6736(99)07026-9  0.31
1999 Yu L, Heere-Ress E, Boucher B, Defesche JC, Kastelein J, Lavoie MA, Genest J. Familial hypercholesterolemia. Acceptor splice site (G-->C) mutation in intron 7 of the LDL-R gene: alternate RNA editing causes exon 8 skipping or a premature stop codon in exon 8. LDL-R(Honduras-1) [LDL-R1061(-1) G-->C]. Atherosclerosis. 146: 125-31. PMID 10487495 DOI: 10.1016/S0021-9150(99)00109-4  0.3
1999 Genest J, Lavoie M. Homozygous Familial Hypercholesterolemia The New England Journal of Medicine. 341: 490-490. PMID 10441605 DOI: 10.1056/Nejm199908123410705  0.327
1999 Marcil M, Yu L, Krimbou L, Boucher B, Oram JF, Cohn JS, Genest J. Cellular Cholesterol Transport and Efflux in Fibroblasts Are Abnormal in Subjects With Familial HDL Deficiency Arteriosclerosis, Thrombosis, and Vascular Biology. 19: 159-169. PMID 9888879 DOI: 10.1161/01.Atv.19.1.159  0.421
1998 Batal R, Tremblay M, Krimbou L, Mamer O, Davignon J, Genest J, Cohn JS. Familial HDL deficiency characterized by hypercatabolism of mature apoA-I but not proapoA-I. Arteriosclerosis, Thrombosis, and Vascular Biology. 18: 655-64. PMID 9555873 DOI: 10.1161/01.Atv.18.4.655  0.38
1996 Cohn JS, Tremblay M, Amiot M, Bouthillier D, Roy M, Genest J, Davignon J. Plasma concentration of apolipoprotein E in intermediate-sized remnant-like lipoproteins in normolipidemic and hyperlipidemic subjects. Arteriosclerosis, Thrombosis, and Vascular Biology. 16: 149-59. PMID 8548416 DOI: 10.1161/01.Atv.16.1.149  0.384
1996 Marcil M, Krimbou L, Boucher B, Solymoss BC, Cohn JS, Genest J. Abnormal HDL3and apo Al-mediated cellular cholesterol efflux in subjects with familial HDL deficiency Journal of the American College of Cardiology. 27: 385. DOI: 10.1016/S0735-1097(96)82468-5  0.322
1996 Yu L, Qiu S, Genest J. Abnormal regulation of the LDL-R and HMG CoA reductase genes in subjects with familial hypercholesterolemia with the “French Canadian Mutation” Journal of the American College of Cardiology. 27: 385-386. DOI: 10.1016/0021-9150(96)05828-5  0.336
1995 Marcil M, Boucher B, Krimbou L, Solymoss BC, Davignon J, Frohlich J, Genest J. Severe familial HDL deficiency in French-Canadian kindreds. Clinical, biochemical, and molecular characterization. Arteriosclerosis, Thrombosis, and Vascular Biology. 15: 1015-24. PMID 7627690 DOI: 10.1161/01.Atv.15.8.1015  0.377
1990 Konrad EM, Bianchi C, Thibault G, Garcia R, Pelletier S, Genest J, Cantin M. Localization and characterization of binding sites for circulating and cerebroventricular atrial natriuretic factor in rat choroid plexus. Neuroendocrinology. 51: 304-14. PMID 2157994 DOI: 10.1159/000125354  0.301
1988 Kuchel O, Debinski W, Buu NT, Cantin M, Canttn M, Genest J. Ganglionic immunoreactive atrial natriuretic factor in rat experimental hypertension Hypertension. 11: I-47-I-51. PMID 2964403 DOI: 10.1161/01.Hyp.11.2_Pt_2.I47  0.317
1988 Genest J, Larochelle P, Cusson JR, Gutkowska J, Cantin M. The atrial natriuretic factor in hypertension. State of the art lecture. Hypertension. 11: I3-7. PMID 2964402 DOI: 10.1161/01.Hyp.11.2_Pt_2.I3  0.344
1988 Cantin M, Genest J. The heart as an endocrine gland. Hypertension (Dallas, Tex. : 1979). 10: I118-21. PMID 2824360 DOI: 10.1161/01.Hyp.10.5_Pt_2.I118  0.371
1987 Baranowska B, Gutkowska J, Talbot P, Genest J, Cantin M. Plasma immunoreactive atrial natriuretic factor is inhibited by selective blockade of alpha 2-adrenergic receptors in conscious Sprague-Dawley rats. Neuroscience Letters. 76: 119-23. PMID 3035429 DOI: 10.1016/0304-3940(87)90203-5  0.339
1987 Baranowska B, Gutkowska J, Cantin M, Genest J. Plasma immunoreactive atrial natriuretic factor (IR-ANF) increases markedly after alpha 2-adrenergic stimulation with clonidine in normally-hydrated rats. Biochemical and Biophysical Research Communications. 143: 159-63. PMID 3030313 DOI: 10.1016/0006-291X(87)90644-9  0.363
1987 Garcia R, Cantin M, Genest J, Gutkowska J, Thibault G. Body fluids and plasma atrial peptide after its chronic infusion in hypertensive rats. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 185: 352-8. PMID 2955421 DOI: 10.3181/00379727-185-3-Rc2  0.336
1987 Larochelle P, Cusson JR, Gutkowska J, Schiffrin EL, Hamet P, Kuchel O, Genest J, Cantin M. Plasma atrial natriuretic factor concentrations in essential and renovascular hypertension. British Medical Journal (Clinical Research Ed.). 294: 1249-52. PMID 2954611 DOI: 10.1136/Bmj.294.6582.1249  0.335
1987 Baranowska B, Gutkowska J, Lemire A, Cantin M, Genest J. Opposite effects of neuropeptide Y (NPY) and polypeptide YY (PYY) on plasma immunoreactive atrial natriuretic factor (IR-ANF) in rats. Biochemical and Biophysical Research Communications. 145: 680-5. PMID 2954552 DOI: 10.1016/0006-291X(87)91018-7  0.314
1987 Kuchel O, Cuche JL, Hamet P, Tolis G, Messerli FH, Barbeau A, Boucher R, Genest J. Labile (borderline) hypertension--new aspects of a common disorder. Angiology. 26: 619-31. PMID 233754 DOI: 10.1177/000331977502600805  0.331
1987 Cusson JR, Hamet P, Gutkowska J, Kuchel O, Genest J, Cantin M, Larochelle P. Effects of atrial natriuretic factor on natriuresis and cGMP in patients with essential hypertension. Journal of Hypertension. 5: 435-443. DOI: 10.1097/00004872-198708000-00008  0.342
1986 Januszewicz P, Larose P, Ong H, Gutkowska J, Genest J, Cantin M. Effect of atrial natriuretic factor on plasma vasopressin in conscious rats. Peptides. 7: 989-993. PMID 2951661 DOI: 10.1016/0196-9781(86)90126-9  0.336
1986 Genest J. The atrial natriuretic factor. British Heart Journal. 56: 302-16. PMID 2945572 DOI: 10.1136/Hrt.56.4.302  0.342
1986 Gutkowska J, Bonan R, Roy D, Bourassa M, Garcia R, Thibault G, Genest J, Cantin M. Atrial natriuretic factor in human plasma. Biochemical and Biophysical Research Communications. 139: 287-95. PMID 2945552 DOI: 10.1016/S0006-291X(86)80111-5  0.327
1986 Kuchel O, Garcia R, Debinski W, Racz K, Buu NT, Cantin M, Genest J. The blood pressure decrease-induced sympathetic discharge following atrial natriuretic factor administration may offset its natriuretic action. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 182: 570-5. PMID 2942946 DOI: 10.3181/00379727-182-4-Rc4  0.313
1986 Murthy KK, Thibault G, Schiffrin EL, Garcia R, Chartier L, Gutkowska J, Genest J, Cantin M. Disappearance of atrial natriuretic factor from circulation in the rat. Peptides. 7: 241-6. PMID 2942845 DOI: 10.1016/0196-9781(86)90220-2  0.348
1986 Januszewicz P, Gutkowska J, Thibault G, Garcia R, Mercure C, Jolicoeur F, Genest J, Cantin M. Dehydration-induced changes in the secretion of atrial natriuretic factor in Brattleboro rats: effect of water-drinking. Neuroscience Letters. 67: 203-207. PMID 2941703 DOI: 10.1016/0304-3940(86)90398-8  0.311
1986 Gutkowska J, Kuchel O, Racz K, Buu NT, Cantin M, Genest J. Increased plasma immunoreactive atrial natriuretic factor concentrations in salt sensitive Dahl rats. Biochemical and Biophysical Research Communications. 136: 411-6. PMID 2939831 DOI: 10.1016/0006-291X(86)90926-5  0.333
1986 Garcia R, Cantin M, De Léan A, Genest J, Godin J, Gutkowska J, Schiffrin EL, Thibault G. Comparative biological activities of ANF (Arg 101-Tyr 126) and the synthetic form of circulating ANF (Ser 99-Tyr 126). Biochemical and Biophysical Research Communications. 135: 987-93. PMID 2938586 DOI: 10.1016/0006-291X(86)91025-9  0.306
1986 Debinski W, Kuchel O, Buu NT, Garcia R, Cantin M, Genest J. Involvement of the adrenal glands in the action of the atrial natriuretic factor Proceedings of the Society For Experimental Biology and Medicine. 181: 318-324. PMID 2935881 DOI: 10.3181/00379727-181-2-Rc1  0.302
1986 Thibault G, Garcia R, Gutkowska J, Genest J, Cantin M. Atrial natriuretic factor. Circulation. 75. PMID 2872046 DOI: 10.2165/00003495-198631050-00001  0.365
1986 Kuchel O, Buu NT, Larochelle P, Hamet P, Genest J. Episodic Dopamine Discharge in Paroxysmal Hypertension: Page’s Syndrome Revisited Archives of Internal Medicine. 146: 1315-1320. DOI: 10.1001/Archinte.1986.00360190079011  0.321
1985 Gutkowska J, Horký K, Thibault G, Januszewicz P, Cantin M, Genest J. Atrial natriuretic factor is a circulating hormone. Biochemical and Biophysical Research Communications. 125: 315-23. PMID 6542365 DOI: 10.1016/S0006-291X(84)80370-8  0.307
1985 Garcia R, Thibault G, Gutkowska J, Horký K, Hamet P, Cantin M, Genest J. Chronic infusion of low doses of atrial natriuretic factor (ANF Arg 101-Tyr 126) reduces blood pressure in conscious SHR without apparent changes in sodium excretion. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 179: 396-401. PMID 4001134 DOI: 10.3181/00379727-179-Rc1Aa  0.301
1985 Kuchel O, Buu NT, Hamet P, Larochelle P, Gutkowska J, Schiffrin EL, Bourque M, Genest J. Orthostatic hypotension: a posture-induced hyperdopaminergic state. The American Journal of the Medical Sciences. 289: 3-11. PMID 3881951 DOI: 10.1097/00000441-198501000-00001  0.333
1985 Garcia R, Thibault G, Gutkowska J, Hamet P, Cantin M, Genest J. Effect of chronic infusion of synthetic atrial natriuretic factor (ANF 8-33) in conscious two-kidney, one-clip hypertensive rats. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 178: 155-9. PMID 3880894 DOI: 10.3181/00379727-178-Rc12  0.301
1985 Garcia R, Gutkowska J, Genest J, Cantin M, Thibault G. Reduction of blood pressure and increased diuresis and natriuresis during chronic infusion of atrial natriuretic factor (ANF Arg 101-Tyr 126) in conscious one-kidney, one-clip hypertensive rats. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 179: 539-45. PMID 3161083 DOI: 10.3181/00379727-179-4-Rc1  0.31
1985 Pang SC, Hoang MC, Tremblay J, Cantin M, Garcia R, Genest J, Hamet P. Effect of natural and synthetic atrial natriuretic factor on arterial blood pressure, natriuresis and cyclic GMP excretion in spontaneously hypertensive rats. Clinical Science (London, England : 1979). 69: 721-6. PMID 2998690 DOI: 10.1042/Cs0690721  0.31
1985 Cantin M, Genest J. The heart and the atrial natriuretic factor. Endocrine Reviews. 6: 107-27. PMID 2988929 DOI: 10.1210/Edrv-6-2-107  0.3
1985 Anand-Srivastava MB, Genest J, Cantin M. Inhibitory effect of atrial natriuretic factor on adenylate cyclase activity in adrenal cortical membranes. Febs Letters. 181: 199-202. PMID 2982657 DOI: 10.1016/0014-5793(85)80259-3  0.305
1985 Garcia R, Debinski W, Gutkowska J, Kuchel O, Thibault G, Genest J, Cantin M. Gluco- and mineralocorticoids may regulate the natriuretic effect and the synthesis and release of atrial natriuretic factor by the rat atria in vivo Biochemical and Biophysical Research Communications. 131: 806-814. PMID 2932106 DOI: 10.1016/0006-291X(85)91311-7  0.363
1984 Desjardins-Giasson S, Gutkowska J, Garcia R, Genest J. Release of prostaglandins by the mesenteric artery of the renovascular and spontaneously hypertensive rat. Canadian Journal of Physiology and Pharmacology. 62: 89-93. PMID 6546893 DOI: 10.1139/Y84-014  0.316
1984 Anand-Srivastava MB, Franks DJ, Cantin M, Genest J. Atrial natriuretic factor inhibits adenylate cyclase activity. Biochemical and Biophysical Research Communications. 121: 855-62. PMID 6540085 DOI: 10.1016/0006-291X(84)90756-3  0.317
1984 Garcia R, Thibault G, Cantin M, Genest J. Effect of a purified atrial natriuretic factor on rat and rabbit vascular strips and vascular beds. The American Journal of Physiology. 247: R34-9. PMID 6540055 DOI: 10.1152/Ajpregu.1984.247.1.R34  0.329
1984 Garcia R, Constantopoulos G, Gutkowska J, Genest J. Effect of a potassium-deficient diet on arterial blood pressure, plasma and tissue cations, and tissue norepinephrine in the hypertensive dog. Canadian Journal of Physiology and Pharmacology. 61: 1473-7. PMID 6367910 DOI: 10.1139/Y83-210  0.329
1984 Thibault G, Garcia R, Cantin M, Genest J. Atrial natriuretic factor and urinary kallikrein in the rat: antagonistic factors? Canadian Journal of Physiology and Pharmacology. 62: 645-9. PMID 6204730 DOI: 10.1139/Y84-105  0.314
1984 Schiffrin EL, Gutkowska J, Thibault G, Genest J. Effect of enalapril (MK-421), an orally active angiotensin I converting enzyme inhibitor, on blood pressure, active and inactive plasma renin, urinary prostaglandin E2, and kallikrein excretion in conscious rats. Canadian Journal of Physiology and Pharmacology. 62: 116-23. PMID 6143602 DOI: 10.1139/Y84-019  0.363
1984 Hamet P, Tremblay J, Pang SC, Garcia R, Thibault G, Gutkowska J, Cantin M, Genest J. Effect of native and synthetic atrial natriuretic factor on cyclic GMP. Biochemical and Biophysical Research Communications. 123: 515-27. PMID 6091631 DOI: 10.1016/0006-291X(84)90260-2  0.329
1984 De Léan A, Racz K, Gutkowska J, Nguyen TT, Cantin M, Genest J. Specific receptor-mediated inhibition by synthetic atrial natriuretic factor of hormone-stimulated steroidogenesis in cultured bovine adrenal cells. Endocrinology. 115: 1636-8. PMID 6090110 DOI: 10.1210/Endo-115-4-1636  0.306
1983 Anand-Srivastava MB, Cantin M, Genest J. Altered hormone sensitivity of adenylate cyclase in myocardial sarcolemma of renal hypertensive rats. Biochemical Pharmacology. 32: 2857-62. PMID 6684927 DOI: 10.1016/0006-2952(83)90389-1  0.316
1983 Buu NT, Kuchel O, Genest J. Changes of catecholamines in central and peripheral tissues and in the urines of deoxycorticosterone--salt hypertensive rats. Canadian Journal of Physiology and Pharmacology. 61: 888-92. PMID 6627129 DOI: 10.1139/Y83-134  0.31
1983 Genest J. Volume hormones and blood pressure. Annals of Internal Medicine. 98: 744-9. PMID 6303174 DOI: 10.7326/0003-4819-98-5-744  0.31
1983 Schiffrin EL, Garcia R, Gutkowska J, Genest J. Role of the pituitary in the effects of tonin on adrenal secretion of the rat. Canadian Journal of Physiology and Pharmacology. 61: 201-6. PMID 6301666 DOI: 10.1139/Y83-031  0.343
1983 Garcia R, Thibault G, Gutkowska J, Genest J. Release of tonin and of kallikrein by perfused rat submaxillary gland. The American Journal of Physiology. 244: R228-34. PMID 6297317 DOI: 10.1152/Ajpregu.1983.244.2.R228  0.311
1983 Nowaczynski W, Murakami T, Richardson K, Genest J. Increased aldosterone plasma protein binding in women on combined oral contraceptives throughout the menstrual cycle. The Journal of Clinical Endocrinology and Metabolism. 47: 193-9. PMID 263655 DOI: 10.1210/Jcem-47-1-193  0.327
1982 Kuchel O, Buu NT, Hamet P, Larochelle P, Bourque M, Genest J. Dopamine surges in hyperadrenergic essential hypertension. Hypertension. 4: 845-52. PMID 7141610 DOI: 10.1161/01.Hyp.4.6.845  0.304
1982 Desjardins-Giasson S, Gutkowska J, Garcia R, Genest J. Effect of angiotensin ii and norepinephrine on release of prostaglandins E2 and I2 by the perfused rat mesenteric artery. Prostaglandins. 24: 105-14. PMID 6750695 DOI: 10.1016/0090-6980(82)90182-4  0.315
1982 Schiffrin EL, Garcia R, Gutkowska J, Lis M, Genest J. Effects of tonin on the adrenal secretion in the rat. Hypertension (Dallas, Tex. : 1979). 3: II-9-13. PMID 6271674 DOI: 10.1161/01.Hyp.3.6_Pt_2.Ii-9  0.325
1982 Schiffrin EL, Garcia R, Gutkowska J, Boucher R, Genest J. Pressor effect of tonin in anephric animals. Canadian Journal of Physiology and Pharmacology. 59: 864-71. PMID 6271377 DOI: 10.1139/Y81-129  0.349
1981 Schiffrin EL, Gutkowska J, Genest J. Mechanism of Captopril-induced renin release in conscious rats. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 167: 327-32. PMID 7019923 DOI: 10.3181/00379727-167-41173  0.334
1981 Garcia R, Schiffrin EL, Thibault G, Genest J. Effects of tonin, an angiotensin II-forming enzyme, on vascular smooth muscle in the normal rabbit. Hypertension (Dallas, Tex. : 1979). 3: I101-6. PMID 6266953 DOI: 10.1161/01.Hyp.3.3_Pt_2.I101  0.317
1980 Kuchel O, Buu NT, Vecsei P, Bourque M, Hamet P, Genest J. Are plasma aldosterone surges in primary aldosteronism due to a loss of an inhibitory dopaminergic control? The Journal of Clinical Endocrinology and Metabolism. 51: 337-44. PMID 7190577 DOI: 10.1210/Jcem-51-2-337  0.301
1979 Kuchel O, Buu NT, Unger T, Lis M, Genest J. Free and conjugated plasma and urinary dopamine in human hypertension. The Journal of Clinical Endocrinology and Metabolism. 48: 425-9. PMID 429495 DOI: 10.1210/Jcem-48-3-425  0.306
1979 Major P, Kuchel O, Boucher R, Nowaczynski W, Genest J. Selective hypopituitarism with severe hyponatremia and secondary hyporeninism. The Journal of Clinical Endocrinology and Metabolism. 46: 15-9. PMID 221513 DOI: 10.1210/Jcem-46-1-15  0.339
1978 Boucher R, Garcia R, Gutkowska J, Demassieux S, Genest J. Tonin–Angiotensin II System in Hypertension Clinical Science. 55: 183s-186s. DOI: 10.1042/Cs055183S  0.313
1977 Komatsu Y, Constantopoulos G, Gutkowska J, Rojo-Ortega JM, Genest J. Effects of reserpine on water, cation, and norepinephrine contents of cardiovascular tissues of normotensive dogs. Canadian Journal of Physiology and Pharmacology. 55: 206-11. PMID 871953 DOI: 10.1139/Y77-030  0.304
1977 Kuchel O, Buu NT, Hamet P, Guthrie GP, Cuche JL, Boucher R, Genest J. Catecholamines, cyclic AMP and renin in two contrasting forms of essential hypertension. Contributions to Nephrology. 8: 27-36. PMID 19203 DOI: 10.1159/000400611  0.315
1976 Honda M, Nowaczynski W, Messerli FH, Kuchel O, Genest J. Plasma deoxycorticosterone and aldosterone in essential hypertension. Journal of Steroid Biochemistry. 7: 565-9. PMID 183059 DOI: 10.1016/0022-4731(76)90078-9  0.367
1976 Messerli FH, Nowaczynski W, Honda M, Genest J, Kuchel O. Effects of ACTH on steroid metabolism. The Journal of Clinical Endocrinology and Metabolism. 42: 1074-80. PMID 180044 DOI: 10.1210/Jcem-42-6-1074  0.333
1975 Kusumoto M, Constantopoulos G, Genest J, Ganten D, Ganten U, Rojo-Ortega JM, Boucher R. Effects of hydrochlorothiazide on water, cation, and norepinephrine contents of cardiovascular tissues of renovascular hypertensive dogs. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 147: 769-74. PMID 4445165 DOI: 10.3181/00379727-147-38435  0.309
1975 Dornier A, Genest J, Boucher R, Nowaczynski W, Rojo-Ortega M, Kuchel O, Granger P. Effect of propranolol on plasma renin activity, renal cortex renin, and adrenal and brain isorenins in rats. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 150: 521-4. PMID 1208570 DOI: 10.3181/00379727-150-39069  0.353
1975 Kuchel O, Hamet P, Cuche JL, Tolis G, Fraysse J, Genest J. Urinary and plasma cyclic adenosine 3',5'-monophosphate in patients with idiopathic edema. The Journal of Clinical Endocrinology and Metabolism. 41: 282-9. PMID 169278 DOI: 10.1210/Jcem-41-2-282  0.339
1975 Rosas R, Rojo-Ortega JM, Ganten D, Boucher R, Genest J. The Renin-Angiotensin System in Rats Made Hypertensive by Ligation of the Kidney Poles Proceedings of the Society For Experimental Biology and Medicine. 148: 562-567. PMID 164676 DOI: 10.3181/00379727-148-38584  0.309
1974 Kubo S, Ganten D, Ganten U, Nowaczynski W, Genest J. Plasma steroids in rats with experimental ectopic pituitary tumor and arterial hypertension. Endocrinology. 94: 459-63. PMID 4810381 DOI: 10.1210/Endo-94-2-459  0.335
1974 Cuche J, Kuchel O, Barbeau A, Langlois Y, Boucher R, Genest J. Autonomic Nervous System and Benign Essential Hypertension in Man: II. Circulatory and Hormonal Responses to Upright Posture Circulation Research. 35: 290-297. DOI: 10.1161/01.Res.35.2.290  0.317
1973 Cuche JL, Kuchel O, Barbeau A, Boucher R, Genest J. Relationship between the adrenergic nervous system and renin during adaptation to upright posture: a possible role for 3,4-dihydroxyphenethylamine (dopamine). Clinical Science. 43: 481-91. PMID 4653587 DOI: 10.1042/Cs0430481  0.312
1973 Sambhi MP, Crane MG, Genest J. Essential Hypertension: New Concepts About Mechanisms Annals of Internal Medicine. 79: 411-424. PMID 4355954 DOI: 10.7326/0003-4819-79-3-411  0.307
1973 Kurihara H, Gregory A, Dewailly P, Boucher R, Genest J. Effects of changes in sodium balance and of experimental renal hypertension on plasma angiotensin I converting enzyme activity of rabbits. The Tohoku Journal of Experimental Medicine. 109: 19-27. PMID 4352132 DOI: 10.1620/Tjem.109.19  0.308
1972 Nowaczynski W, Kuchel O, Genest J. A decreased metabolic clearance rate of aldosterone in benign essential hypertension. The Journal of Clinical Investigation. 50: 2184-90. PMID 5116208 DOI: 10.1172/Jci106713  0.309
1971 Hayduk K, Boucher R, Genest J. Renin activity in urine, plasma, and renal cortex of dogs during changes in sodium balance. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 136: 399-402. PMID 5544470 DOI: 10.3181/00379727-136-35273  0.315
1971 Granger P, Rojo-Ortega JM, Casado Pérez S, Boucher R, Genest J. The renin-angiotensin system in newborn dogs. Canadian Journal of Physiology and Pharmacology. 49: 134-8. PMID 4328059 DOI: 10.1139/Y71-019  0.338
1970 Hayduk K, Brecht HM, Vladutiu A, Simard S, Rojo-Ortega JM, Belleau L, Boucher R, Genest J. Renin activity and norepinephrine, cation, and water contents of cardiovascular tissue of dogs with congestive heart failure, and ascites. Canadian Journal of Physiology and Pharmacology. 48: 463-8. PMID 5464322 DOI: 10.1139/Y70-071  0.304
1970 Granger P, Boucher R, Genest J. A method for determination of renin activity in dog's plasma and renal tissue. Canadian Journal of Physiology and Pharmacology. 48: 457-62. PMID 4317167 DOI: 10.1139/Y70-070  0.314
1969 Barbeau A, Gillo-Joffroy L, Boucher R, Nowaczynski W, Genest J. Renin-aldosterone system in Parkinson's disease. Science (New York, N.Y.). 165: 291-2. PMID 5787986 DOI: 10.1126/Science.165.3890.291  0.324
1969 Rosenthal J, Boucher R, Rojo-Ortega JM, Genest J. Renin activity in aortic tissue of rats. Canadian Journal of Physiology and Pharmacology. 47: 53-6. PMID 5761846 DOI: 10.1139/Y69-009  0.34
1969 Rojo-Ortega JM, Rosenthal J, Boucher R, Genest J. Effects of high temperature and acute diuresis on glucose-6-phosphate dehydrogenase activity of mascula densa and plasma renin activity in rats. Canadian Journal of Physiology and Pharmacology. 47: 837-40. PMID 5346439 DOI: 10.1139/Y69-139  0.323
1968 Rosenthal J, Boucher R, Nowaczynski W, Genest J. Acute changes in plasma volume, renin activity, and free aldosterone levels in healthy subjects following Fursemide administration. Canadian Journal of Physiology and Pharmacology. 46: 85-91. PMID 5642446 DOI: 10.1139/Y68-015  0.339
1966 Champlain JD, Genest J, Veyratt R, Boucher R. Factors Controlling Renin in Man Jama Internal Medicine. 117: 355-363. DOI: 10.1001/Archinte.1966.03870090039007  0.319
1955 Nowaczynski W, Genest J. Prednisone And Plasma Lipids The Journal of Clinical Endocrinology and Metabolism. 15: 1308-1312. PMID 13263421 DOI: 10.1210/Jcem-15-10-1308  0.356
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