| Year |
Citation |
Score |
| 2020 |
Lin HC, Chen YJ, Wei YH, Chuang YT, Hsieh SH, Hsieh JY, Hsieh YL, Ojcius DM, Huang KY, Chung IC, Yuan SN, Chang YS, Chen LC. Cbl Negatively Regulates NLRP3 Inflammasome Activation through GLUT1-Dependent Glycolysis Inhibition. International Journal of Molecular Sciences. 21. PMID 32707731 DOI: 10.3390/Ijms21145104 |
0.351 |
|
| 2020 |
Al-Kuhlani M, Lambert G, Pal S, de la Maza L, Ojcius DM. Immune response against Chlamydia trachomatis via toll-like receptors is negatively regulated by SIGIRR. Plos One. 15: e0230718. PMID 32210474 DOI: 10.1371/Journal.Pone.0230718 |
0.397 |
|
| 2020 |
Shenker BJ, Walker LM, Zekavat Z, Ojcius DM, Huang PR, Boesze-Battaglia K. Cytolethal distending toxin-induced release of interleukin-1β by human macrophages is dependent upon activation of glycogen synthase kinase (GSK) 3β, spleen tyrosine kinase (Syk) and the noncanonical inflammasome. Cellular Microbiology. PMID 32068949 DOI: 10.1111/Cmi.13194 |
0.383 |
|
| 2019 |
Chung IC, Chen LC, Tsang NM, Chuang WY, Liao TC, Yuan SN, OuYang CN, Ojcius DM, Wu CC, Chang YS. Mitochondrial oxidative phosphorylation complex regulates NLRP3 inflammasome activation and predicts patient survival in nasopharyngeal carcinoma. Molecular & Cellular Proteomics : McP. PMID 31723016 DOI: 10.1074/Mcp.Ra119.001808 |
0.315 |
|
| 2019 |
Ojcius DM, Jafari A, Yeruva L, Schindler CW, Abdul-Sater AA. Dicer regulates activation of the NLRP3 inflammasome. Plos One. 14: e0215689. PMID 31013297 DOI: 10.1371/Journal.Pone.0215689 |
0.315 |
|
| 2019 |
Li Y, Li KX, Hu WL, Ojcius DM, Fang JQ, Li SJ, Lin X, Yan J. Endocytic recycling and vesicular transport systems mediate transcytosis of across cell monolayer. Elife. 8. PMID 31012847 DOI: 10.7554/Elife.44594 |
0.334 |
|
| 2019 |
Almeida-da-Silva CLC, Alpagot T, Zhu Y, Lee SS, Roberts BP, Hung SC, Tang N, Ojcius DM. is present in the dental plaque of periodontitis patients and stimulates an inflammatory response in gingival epithelial cells. Microbial Cell (Graz, Austria). 6: 197-208. PMID 30956972 DOI: 10.15698/Mic2019.04.674 |
0.392 |
|
| 2019 |
Chung IC, OuYang CN, Yuan SN, Lin HC, Huang KY, Wu PS, Liu CY, Tsai KJ, Loi LK, Chen YJ, Chung AK, Ojcius DM, Chang YS, Chen LC. Pretreatment with a Heat-Killed Probiotic Modulates the NLRP3 Inflammasome and Attenuates Colitis-Associated Colorectal Cancer in Mice. Nutrients. 11. PMID 30823406 DOI: 10.3390/Nu11030516 |
0.325 |
|
| 2018 |
Chung IC, Yuan SN, OuYang CN, Lin HC, Huang KY, Chen YJ, Chung AK, Chu CL, Ojcius DM, Chang YS, Chen LC. Src-family kinase-Cbl axis negatively regulates NLRP3 inflammasome activation. Cell Death & Disease. 9: 1109. PMID 30382081 DOI: 10.1038/S41419-018-1163-Z |
0.348 |
|
| 2018 |
Johnson L, Almeida-da-Silva CLC, Takiya CM, Figliuolo V, Rocha GM, Weissmüller G, Scharfstein J, Coutinho-Silva R, Ojcius DM. Oral infection of mice with Fusobacterium nucleatum results in macrophage recruitment to the dental pulp and bone resorption. Biomedical Journal. 41: 184-193. PMID 30080658 DOI: 10.1016/J.Bj.2018.05.001 |
0.375 |
|
| 2018 |
Du P, Li SJ, Ojcius DM, Li KX, Hu WL, Lin X, Sun AH, Yan J. A novel Fas-binding outer membrane protein and lipopolysaccharide of Leptospira interrogans induce macrophage apoptosis through the Fas/FasL-caspase-8/-3 pathway. Emerging Microbes & Infections. 7: 135. PMID 30061622 DOI: 10.1038/S41426-018-0135-9 |
0.345 |
|
| 2018 |
Häfner SJ, Ojcius DM. Microbes and Infection turns 20. Microbes and Infection. 20: 451-454. PMID 29857123 DOI: 10.1016/J.Micinf.2018.05.002 |
0.315 |
|
| 2017 |
Peng H, Liu Y, Ojcius DM, Lee C, Chen R, Huang P, Martel J, Young JD. Mineral particles stimulate innate immunity through neutrophil extracellular traps containing HMGB1. Scientific Reports. 7: 16628. PMID 29192209 DOI: 10.1038/S41598-017-16778-4 |
0.332 |
|
| 2017 |
Hu WL, Dong HY, Li Y, Ojcius DM, Li SJ, Yan J. Bid-Induced Release of AIF/EndoG from Mitochondria Causes Apoptosis of Macrophages during Infection with Leptospira interrogans. Frontiers in Cellular and Infection Microbiology. 7: 471. PMID 29184851 DOI: 10.3389/Fcimb.2017.00471 |
0.371 |
|
| 2017 |
Dong SL, Hu WL, Ge YM, Ojcius DM, Lin X, Yan J. A leptospiral AAA+ chaperone-Ntn peptidase complex, HslUV, contributes to the intracellular survival of Leptospira interrogans in hosts and the transmission of leptospirosis. Emerging Microbes & Infections. 6: e105. PMID 29184154 DOI: 10.1038/Emi.2017.93 |
0.341 |
|
| 2017 |
Singh A, Koduru B, Carlisle C, Akhter H, Liu RM, Schroder K, Brandes RP, Ojcius DM. NADPH oxidase 4 modulates hepatic responses to lipopolysaccharide mediated by Toll-like receptor-4. Scientific Reports. 7: 14346. PMID 29085012 DOI: 10.1038/S41598-017-14574-8 |
0.305 |
|
| 2017 |
Hung SC, Huang PR, Almeida-da-Silva CLC, Atanasova KR, Yilmaz O, Ojcius DM. NLRX1 modulates differentially NLRP3 inflammasome activation and NF-κB signaling during Fusobacterium nucleatum infection. Microbes and Infection. PMID 29024797 DOI: 10.1016/J.Micinf.2017.09.014 |
0.403 |
|
| 2017 |
Coutinho CMLM, Coutinho-Silva R, Zinkevich V, Pearce CB, Ojcius DM, Beech I. Sulphate-reducing bacteria from ulcerative colitis patients induce apoptosis of gastrointestinal epithelial cells. Microbial Pathogenesis. 112: 126-134. PMID 28963010 DOI: 10.1016/J.Micpath.2017.09.054 |
0.335 |
|
| 2017 |
Chen W, Foo SS, Zaid A, Teng TS, Herrero LJ, Wolf S, Tharmarajah K, Vu LD, van Vreden C, Taylor A, Freitas JR, Li RW, Woodruff TM, Gordon R, Ojcius DM, et al. Specific inhibition of NLRP3 in chikungunya disease reveals a role for inflammasomes in alphavirus-induced inflammation. Nature Microbiology. PMID 28848230 DOI: 10.1038/S41564-017-0015-4 |
0.37 |
|
| 2017 |
Chen X, Li SJ, Ojcius DM, Sun AH, Hu WL, Lin X, Yan J. Mononuclear-macrophages but not neutrophils act as major infiltrating anti-leptospiral phagocytes during leptospirosis. Plos One. 12: e0181014. PMID 28700741 DOI: 10.1371/Journal.Pone.0181014 |
0.323 |
|
| 2017 |
Wu Q, Allouch A, Paoletti A, Leteur C, Mirjolet C, Martins I, Voisin L, Law F, Dakhli H, Mintet E, Thoreau M, Muradova Z, Gauthier M, Caron O, Milliat F, ... Ojcius DM, et al. NOX2-dependent ATM kinase activation dictates pro-inflammatory macrophage phenotype and improves effectiveness to radiation therapy. Cell Death and Differentiation. PMID 28574504 DOI: 10.1038/Cdd.2017.91 |
0.322 |
|
| 2016 |
Pettengill MA, Abdul-Sater AA, Coutinho-Silva R, Ojcius DM. Danger signals, inflammasomes, and the intricate intracellular lives of chlamydiae. Biomedical Journal. 39: 306-315. PMID 27884377 DOI: 10.1016/J.Bj.2016.07.001 |
0.362 |
|
| 2016 |
Atanasova K, Lee J, Roberts J, Lee K, Ojcius DM, Yilmaz Ö. Nucleoside-Diphosphate-Kinase of P. gingivalis is Secreted from Epithelial Cells In the Absence of a Leader Sequence Through a Pannexin-1 Interactome. Scientific Reports. 6: 37643. PMID 27883084 DOI: 10.1038/Srep37643 |
0.394 |
|
| 2016 |
Chung IC, OuYang CN, Yuan SN, Li HP, Chen JT, Shieh HR, Chen YJ, Ojcius DM, Chu CL, Yu JS, Chang YS, Chen LC. Pyk2 activates the NLRP3 inflammasome by directly phosphorylating ASC and contributes to inflammasome-dependent peritonitis. Scientific Reports. 6: 36214. PMID 27796369 DOI: 10.1038/Srep36214 |
0.314 |
|
| 2016 |
Martel J, Lai HC, Ko YF, Young JD, Ojcius DM. Alternative functions for the multifarious inflammasome. Biomedical Journal. 39: 183-7. PMID 27621119 DOI: 10.1016/J.Bj.2016.06.001 |
0.346 |
|
| 2016 |
Lu CC, Hsu YJ, Chang CJ, Lin CS, Martel J, Ojcius DM, Ko YF, Lai HC, Young JD. Immunomodulatory properties of medicinal mushrooms: differential effects of water and ethanol extracts on NK cell-mediated cytotoxicity. Innate Immunity. PMID 27469258 DOI: 10.1177/1753425916661402 |
0.3 |
|
| 2016 |
Chen MF, Weng KF, Huang SY, Liu YC, Tseng SN, Ojcius DM, Shih SR. Pretreatment with a heat-killed probiotic modulates monocyte chemoattractant protein-1 and reduces the pathogenicity of influenza and enterovirus 71 infections. Mucosal Immunology. PMID 27072606 DOI: 10.1038/Mi.2016.31 |
0.372 |
|
| 2015 |
Chen HH, Sun AH, Ojcius DM, Hu WL, Ge YM, Lin X, Li LJ, Pan JP, Yan J. Eosinophils from Murine Lamina Propria Induce Differentiation of Naïve T Cells into Regulatory T Cells via TGF-β1 and Retinoic Acid. Plos One. 10: e0142881. PMID 26587591 DOI: 10.1371/Journal.Pone.0142881 |
0.318 |
|
| 2015 |
Santana P, Martel J, Lai HC, Perfettini JL, Kanellopoulos J, Young JD, Coutinho-Silva R, Ojcius DM. Is the Inflammasome Relevant for Epithelial Cell Function? Microbes and Infection / Institut Pasteur. PMID 26546965 DOI: 10.1016/J.Micinf.2015.10.007 |
0.388 |
|
| 2015 |
Ramos-Junior ES, Morandini AC, Almeida-da-Silva CL, Franco EJ, Potempa J, Nguyen KA, Oliveira AC, Zamboni DS, Ojcius DM, Scharfstein J, Coutinho-Silva R. A Dual Role for P2X7 Receptor during Porphyromonas gingivalis Infection. Journal of Dental Research. 94: 1233-42. PMID 26152185 DOI: 10.1177/0022034515593465 |
0.347 |
|
| 2015 |
Yilmaz Ö, Ojcius DM. A new frontier: oral microbes without borders. Microbes and Infection / Institut Pasteur. PMID 26002119 DOI: 10.1016/J.Micinf.2015.05.002 |
0.304 |
|
| 2015 |
Johnson L, Atanasova KR, Bui PQ, Lee J, Hung SC, Yilmaz Ö, Ojcius DM. Porphyromonas gingivalis attenuates ATP-mediated inflammasome activation and HMGB1 release through expression of a nucleoside-diphosphate kinase. Microbes and Infection / Institut Pasteur. 17: 369-77. PMID 25828169 DOI: 10.1016/J.Micinf.2015.03.010 |
0.412 |
|
| 2015 |
Shenker BJ, Ojcius DM, Walker LP, Zekavat A, Scuron MD, Boesze-Battaglia K. Aggregatibacter actinomycetemcomitans cytolethal distending toxin activates the NLRP3 inflammasome in human macrophages, leading to the release of proinflammatory cytokines. Infection and Immunity. 83: 1487-96. PMID 25644004 DOI: 10.1128/Iai.03132-14 |
0.391 |
|
| 2015 |
Komi KK, Ge YM, Xin XY, Ojcius DM, Sun D, Hu WL, Zhao X, Lin X, Yan J. ChpK and MazF of the toxin-antitoxin modules are involved in the virulence of Leptospira interrogans during infection. Microbes and Infection / Institut Pasteur. 17: 34-47. PMID 25461800 DOI: 10.1016/J.Micinf.2014.10.010 |
0.396 |
|
| 2014 |
Lin SJ, Lo M, Kuo RL, Shih SR, Ojcius DM, Lu J, Lee CK, Chen HC, Lin MY, Leu CM, Lin CN, Tsai CH. The pathological effects of CCR2+ inflammatory monocytes are amplified by an IFNAR1-triggered chemokine feedback loop in highly pathogenic influenza infection. Journal of Biomedical Science. 21: 99. PMID 25407417 DOI: 10.1186/S12929-014-0099-6 |
0.336 |
|
| 2014 |
Weng KF, Hung CT, Hsieh PT, Li ML, Chen GW, Kung YA, Huang PN, Kuo RL, Chen LL, Lin JY, Wang RY, Chen SJ, Tang P, Horng JT, Huang HI, ... ... Ojcius DM, et al. A cytoplasmic RNA virus generates functional viral small RNAs and regulates viral IRES activity in mammalian cells. Nucleic Acids Research. 42: 12789-805. PMID 25352551 DOI: 10.1093/Nar/Gku952 |
0.301 |
|
| 2014 |
Lin CS, Chang CJ, Lu CC, Martel J, Ojcius DM, Ko YF, Young JD, Lai HC. Impact of the gut microbiota, prebiotics, and probiotics on human health and disease. Biomedical Journal. 37: 259-68. PMID 25179725 DOI: 10.4103/2319-4170.138314 |
0.302 |
|
| 2014 |
Wang LJ, Huang HY, Huang MP, Liou W, Chang YT, Wu CC, Ojcius DM, Chang YS. The microtubule-associated protein EB1 links AIM2 inflammasomes with autophagy-dependent secretion. The Journal of Biological Chemistry. 289: 29322-33. PMID 25164813 DOI: 10.1074/Jbc.M114.559153 |
0.314 |
|
| 2014 |
Lu CC, Wu TS, Hsu YJ, Chang CJ, Lin CS, Chia JH, Wu TL, Huang TT, Martel J, Ojcius DM, Young JD, Lai HC. NK cells kill mycobacteria directly by releasing perforin and granulysin. Journal of Leukocyte Biology. 96: 1119-29. PMID 25139289 DOI: 10.1189/Jlb.4A0713-363Rr |
0.385 |
|
| 2014 |
Häcker G, Heuer D, Ojcius DM. Is the hoopla over CPAF justified? Pathogens and Disease. 72: 1-2. PMID 25113036 DOI: 10.1111/2049-632X.12211 |
0.345 |
|
| 2014 |
Johnson L, Gaab EM, Sanchez J, Bui PQ, Nobile CJ, Hoyer KK, Peterson MW, Ojcius DM. Valley fever: danger lurking in a dust cloud. Microbes and Infection / Institut Pasteur. 16: 591-600. PMID 25038397 DOI: 10.1016/J.Micinf.2014.06.011 |
0.306 |
|
| 2014 |
Morandini AC, Ramos-Junior ES, Potempa J, Nguyen KA, Oliveira AC, Bellio M, Ojcius DM, Scharfstein J, Coutinho-Silva R. Porphyromonas gingivalis fimbriae dampen P2X7-dependent interleukin-1β secretion. Journal of Innate Immunity. 6: 831-45. PMID 24925032 DOI: 10.1159/000363338 |
0.339 |
|
| 2014 |
Al-Kuhlani M, Rothchild J, Pal S, de la Maza LM, Ouburg S, Morré SA, Dean D, Ojcius DM. TRAIL-R1 is a negative regulator of pro-inflammatory responses and modulates long-term sequelae resulting from Chlamydia trachomatis infections in humans. Plos One. 9: e93939. PMID 24695582 DOI: 10.1371/Journal.Pone.0093939 |
0.355 |
|
| 2014 |
Sellami H, Said-Sadier N, Znazen A, Gdoura R, Ojcius DM, Hammami A. Chlamydia trachomatis infection increases the expression of inflammatory tumorigenic cytokines and chemokines as well as components of the Toll-like receptor and NF-κB pathways in human prostate epithelial cells. Molecular and Cellular Probes. 28: 147-54. PMID 24613856 DOI: 10.1016/J.Mcp.2014.01.006 |
0.381 |
|
| 2014 |
Li Z, Lou H, Ojcius DM, Sun A, Sun D, Zhao J, Lin X, Yan J. Methyl-accepting chemotaxis proteins 3 and 4 are responsible for Campylobacter jejuni chemotaxis and jejuna colonization in mice in response to sodium deoxycholate. Journal of Medical Microbiology. 63: 343-54. PMID 24403598 DOI: 10.1099/Jmm.0.068023-0 |
0.309 |
|
| 2014 |
Kassegne K, Hu W, Ojcius DM, Sun D, Ge Y, Zhao J, Yang XF, Li L, Yan J. Identification of collagenase as a critical virulence factor for invasiveness and transmission of pathogenic Leptospira species. The Journal of Infectious Diseases. 209: 1105-15. PMID 24277745 DOI: 10.1093/Infdis/Jit659 |
0.318 |
|
| 2014 |
Huang TT, Lai HC, Chen YB, Chen LG, Wu YH, Ko YF, Lu CC, Chang CJ, Wu CY, Martel J, Ojcius DM, Chong KY, Young JD. cis-Resveratrol produces anti-inflammatory effects by inhibiting canonical and non-canonical inflammasomes in macrophages. Innate Immunity. 20: 735-50. PMID 24149798 DOI: 10.1177/1753425913507096 |
0.302 |
|
| 2014 |
Chang CJ, Chen YY, Lu CC, Lin CS, Martel J, Tsai SH, Ko YF, Huang TT, Ojcius DM, Young JD, Lai HC. Ganoderma lucidum stimulates NK cell cytotoxicity by inducing NKG2D/NCR activation and secretion of perforin and granulysin. Innate Immunity. 20: 301-11. PMID 23803412 DOI: 10.1177/1753425913491789 |
0.313 |
|
| 2013 |
Zhao JF, Chen HH, Ojcius DM, Zhao X, Sun D, Ge YM, Zheng LL, Lin X, Li LJ, Yan J. Identification of Leptospira interrogans phospholipase C as a novel virulence factor responsible for intracellular free calcium ion elevation during macrophage death. Plos One. 8: e75652. PMID 24124502 DOI: 10.1371/Journal.Pone.0075652 |
0.318 |
|
| 2013 |
Habbeddine M, Verbeke P, Delarbre C, Moutier R, Prieto S, Ojcius DM, Kanellopoulos-Langevin C. CD1d-restricted NKT cells modulate placental and uterine leukocyte populations during chlamydial infection in mice. Microbes and Infection / Institut Pasteur. 15: 928-38. PMID 23999314 DOI: 10.1016/J.Micinf.2013.08.006 |
0.339 |
|
| 2013 |
Hung SC, Choi CH, Said-Sadier N, Johnson L, Atanasova KR, Sellami H, Yilmaz Ö, Ojcius DM. P2X4 assembles with P2X7 and pannexin-1 in gingival epithelial cells and modulates ATP-induced reactive oxygen species production and inflammasome activation. Plos One. 8: e70210. PMID 23936165 DOI: 10.1371/Journal.Pone.0070210 |
0.372 |
|
| 2013 |
Szaszák M, Chang JC, Leng W, Rupp J, Ojcius DM, Kelley AM. Characterizing the intracellular distribution of metabolites in intact Chlamydia-infected cells by Raman and two-photon microscopy. Microbes and Infection / Institut Pasteur. 15: 461-9. PMID 23541981 DOI: 10.1016/J.Micinf.2013.03.005 |
0.353 |
|
| 2013 |
Hu W, Ge Y, Ojcius DM, Sun D, Dong H, Yang XF, Yan J. p53 signalling controls cell cycle arrest and caspase-independent apoptosis in macrophages infected with pathogenic Leptospira species. Cellular Microbiology. 15: 1642-59. PMID 23521874 DOI: 10.1111/Cmi.12141 |
0.373 |
|
| 2013 |
Huang TT, Chong KY, Ojcius DM, Wu YH, Ko YF, Wu CY, Martel J, Lu CC, Lai HC, Young JD. Hirsutella sinensis mycelium suppresses interleukin-1β and interleukin-18 secretion by inhibiting both canonical and non-canonical inflammasomes. Scientific Reports. 3: 1374. PMID 23459183 DOI: 10.1038/Srep01374 |
0.315 |
|
| 2013 |
Choi CH, Spooner R, DeGuzman J, Koutouzis T, Ojcius DM, Yilmaz Ö. Porphyromonas gingivalis-nucleoside-diphosphate-kinase inhibits ATP-induced reactive-oxygen-species via P2X7 receptor/NADPH-oxidase signalling and contributes to persistence. Cellular Microbiology. 15: 961-76. PMID 23241000 DOI: 10.1111/Cmi.12089 |
0.341 |
|
| 2013 |
Wang A, Al-Kuhlani M, Johnston SC, Ojcius DM, Chou J, Dean D. Transcription factor complex AP-1 mediates inflammation initiated by Chlamydia pneumoniae infection. Cellular Microbiology. 15: 779-94. PMID 23163821 DOI: 10.1111/Cmi.12071 |
0.379 |
|
| 2012 |
Saïd-Sadier N, Ojcius DM. Alarmins, inflammasomes and immunity. Biomedical Journal. 35: 437-49. PMID 23442356 DOI: 10.4103/2319-4170.104408 |
0.383 |
|
| 2012 |
Zhang L, Wang X, Zhang Y, Gong L, Mao H, Feng C, Ojcius DM, Yan J. Rapid and sensitive identification of RNA from the emerging pathogen, coxsackievirus A6. Virology Journal. 9: 298. PMID 23194501 DOI: 10.1186/1743-422X-9-298 |
0.315 |
|
| 2012 |
Pettengill MA, Lam VW, Ollawa I, Marques-da-Silva C, Ojcius DM. Ivermectin inhibits growth of Chlamydia trachomatis in epithelial cells. Plos One. 7: e48456. PMID 23119027 DOI: 10.1371/Journal.Pone.0048456 |
0.358 |
|
| 2012 |
Chen LC, Wang LJ, Tsang NM, Ojcius DM, Chen CC, Ouyang CN, Hsueh C, Liang Y, Chang KP, Chen CC, Chang YS. Tumour inflammasome-derived IL-1β recruits neutrophils and improves local recurrence-free survival in EBV-induced nasopharyngeal carcinoma. Embo Molecular Medicine. 4: 1276-93. PMID 23065753 DOI: 10.1002/Emmm.201201569 |
0.319 |
|
| 2012 |
Pettengill MA, Marques-da-Silva C, Avila ML, d'Arc dos Santos Oliveira S, Lam VW, Ollawa I, Abdul Sater AA, Coutinho-Silva R, Häcker G, Ojcius DM. Reversible inhibition of Chlamydia trachomatis infection in epithelial cells due to stimulation of P2X(4) receptors. Infection and Immunity. 80: 4232-8. PMID 22988022 DOI: 10.1128/Iai.00441-12 |
0.393 |
|
| 2012 |
Wang H, Wu Y, Ojcius DM, Yang XF, Zhang C, Ding S, Lin X, Yan J. Leptospiral hemolysins induce proinflammatory cytokines through Toll-like receptor 2-and 4-mediated JNK and NF-κB signaling pathways. Plos One. 7: e42266. PMID 22870312 DOI: 10.1371/Journal.Pone.0042266 |
0.369 |
|
| 2012 |
Wang LJ, Hsu CW, Chen CC, Liang Y, Chen LC, Ojcius DM, Tsang NM, Hsueh C, Wu CC, Chang YS. Interactome-wide analysis identifies end-binding protein 1 as a crucial component for the speck-like particle formation of activated absence in melanoma 2 (AIM2) inflammasomes. Molecular & Cellular Proteomics : McP. 11: 1230-44. PMID 22869553 DOI: 10.1074/Mcp.M112.020594 |
0.303 |
|
| 2012 |
Huang TT, Ojcius DM, Young JD, Wu YH, Ko YF, Wong TY, Wu CY, Lu CC, Lai HC. The anti-tumorigenic mushroom Agaricus blazei Murill enhances IL-1β production and activates the NLRP3 inflammasome in human macrophages. Plos One. 7: e41383. PMID 22844468 DOI: 10.1371/Journal.Pone.0041383 |
0.323 |
|
| 2012 |
Lai HC, Chang CJ, Yang CH, Hsu YJ, Chen CC, Lin CS, Tsai YH, Huang TT, Ojcius DM, Tsai YH, Lu CC. Activation of NK cell cytotoxicity by the natural compound 2,3-butanediol. Journal of Leukocyte Biology. 92: 807-14. PMID 22802446 DOI: 10.1189/Jlb.0112024 |
0.334 |
|
| 2012 |
Coutinho-Silva R, Ojcius DM. Role of extracellular nucleotides in the immune response against intracellular bacteria and protozoan parasites. Microbes and Infection / Institut Pasteur. 14: 1271-7. PMID 22634346 DOI: 10.1016/J.Micinf.2012.05.009 |
0.373 |
|
| 2012 |
Chen CC, Tsai SH, Lu CC, Hu ST, Wu TS, Huang TT, Saïd-Sadier N, Ojcius DM, Lai HC. Activation of an NLRP3 inflammasome restricts Mycobacterium kansasii infection. Plos One. 7: e36292. PMID 22558425 DOI: 10.1371/Journal.Pone.0036292 |
0.362 |
|
| 2012 |
Shimada K, Crother TR, Karlin J, Dagvadorj J, Chiba N, Chen S, Ramanujan VK, Wolf AJ, Vergnes L, Ojcius DM, Rentsendorj A, Vargas M, Guerrero C, Wang Y, Fitzgerald KA, et al. Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis. Immunity. 36: 401-14. PMID 22342844 DOI: 10.1016/J.Immuni.2012.01.009 |
0.301 |
|
| 2012 |
Zhang L, Zhang C, Ojcius DM, Sun D, Zhao J, Lin X, Li L, Li L, Yan J. The mammalian cell entry (Mce) protein of pathogenic Leptospira species is responsible for RGD motif-dependent infection of cells and animals. Molecular Microbiology. 83: 1006-23. PMID 22329803 DOI: 10.1111/J.1365-2958.2012.07985.X |
0.365 |
|
| 2011 |
Luo Y, Liu Y, Sun D, Ojcius DM, Zhao J, Lin X, Wu D, Zhang R, Chen M, Li L, Yan J. InvA protein is a Nudix hydrolase required for infection by pathogenic Leptospira in cell lines and animals. The Journal of Biological Chemistry. 286: 36852-63. PMID 21862592 DOI: 10.1074/Jbc.M111.219931 |
0.346 |
|
| 2011 |
Marques-da-Silva C, Chaves MM, Chaves SP, Figliuolo VR, Meyer-Fernandes JR, Corte-Real S, Lameu C, Ulrich H, Ojcius DM, Rossi-Bergmann B, Coutinho-Silva R. Infection with Leishmania amazonensis upregulates purinergic receptor expression and induces host-cell susceptibility to UTP-mediated apoptosis. Cellular Microbiology. 13: 1410-28. PMID 21740498 DOI: 10.1111/J.1462-5822.2011.01630.X |
0.41 |
|
| 2011 |
Shimada K, Crother TR, Karlin J, Chen S, Chiba N, Ramanujan VK, Vergnes L, Ojcius DM, Arditi M. Caspase-1 dependent IL-1β secretion is critical for host defense in a mouse model of Chlamydia pneumoniae lung infection. Plos One. 6: e21477. PMID 21731762 DOI: 10.1371/Journal.Pone.0021477 |
0.372 |
|
| 2011 |
Huang TT, Liu FG, Wei CF, Lu CC, Chen CC, Lin HC, Ojcius DM, Lai HC. Activation of multiple apoptotic pathways in human nasopharyngeal carcinoma cells by the prenylated isoflavone, osajin. Plos One. 6: e18308. PMID 21532751 DOI: 10.1371/Journal.Pone.0018308 |
0.354 |
|
| 2011 |
Marques-da-Silva C, Burnstock G, Ojcius DM, Coutinho-Silva R. Purinergic receptor agonists modulate phagocytosis and clearance of apoptotic cells in macrophages. Immunobiology. 216: 1-11. PMID 20471713 DOI: 10.1016/J.Imbio.2010.03.010 |
0.34 |
|
| 2010 |
Abdul-Sater AA, Saïd-Sadier N, Lam VM, Singh B, Pettengill MA, Soares F, Tattoli I, Lipinski S, Girardin SE, Rosenstiel P, Ojcius DM. Enhancement of reactive oxygen species production and chlamydial infection by the mitochondrial Nod-like family member NLRX1. The Journal of Biological Chemistry. 285: 41637-45. PMID 20959452 DOI: 10.1074/Jbc.M110.137885 |
0.356 |
|
| 2010 |
Abdul-Sater AA, Saïd-Sadier N, Padilla EV, Ojcius DM. Chlamydial infection of monocytes stimulates IL-1beta secretion through activation of the NLRP3 inflammasome. Microbes and Infection / Institut Pasteur. 12: 652-61. PMID 20434582 DOI: 10.1016/J.Micinf.2010.04.008 |
0.4 |
|
| 2010 |
Saïd-Sadier N, Padilla E, Langsley G, Ojcius DM. Aspergillus fumigatus stimulates the NLRP3 inflammasome through a pathway requiring ROS production and the Syk tyrosine kinase. Plos One. 5: e10008. PMID 20368800 DOI: 10.1371/Journal.Pone.0010008 |
0.397 |
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| 2010 |
Yao L, Jermanus C, Barbetta B, Choi C, Verbeke P, Ojcius DM, Yilmaz O. Porphyromonas gingivalis infection sequesters pro-apoptotic Bad through Akt in primary gingival epithelial cells. Molecular Oral Microbiology. 25: 89-101. PMID 20331797 DOI: 10.1111/J.2041-1014.2010.00569.X |
0.384 |
|
| 2010 |
Ojcius DM, Kaufmann SH. Microbes and Infection: past, present and future. Microbes and Infection / Institut Pasteur. 12: 1-2. PMID 19944181 DOI: 10.1016/J.Micinf.2009.11.008 |
0.317 |
|
| 2010 |
Yilmaz O, Sater AA, Yao L, Koutouzis T, Pettengill M, Ojcius DM. ATP-dependent activation of an inflammasome in primary gingival epithelial cells infected by Porphyromonas gingivalis. Cellular Microbiology. 12: 188-98. PMID 19811501 DOI: 10.1111/J.1462-5822.2009.01390.X |
0.392 |
|
| 2010 |
Li S, Ojcius DM, Liao S, Li L, Xue F, Dong H, Yan J. Replication or death: distinct fates of pathogenic Leptospira strain Lai within macrophages of human or mouse origin. Innate Immunity. 16: 80-92. PMID 19587003 DOI: 10.1177/1753425909105580 |
0.339 |
|
| 2009 |
Pettengill MA, Lam VW, Ojcius DM. The danger signal adenosine induces persistence of chlamydial infection through stimulation of A2b receptors. Plos One. 4: e8299. PMID 20011598 DOI: 10.1371/Journal.Pone.0008299 |
0.383 |
|
| 2009 |
Luo D, Xue F, Ojcius DM, Zhao J, Mao Y, Li L, Lin X, Yan J. Protein typing of major outer membrane lipoproteins from Chinese pathogenic Leptospira spp. and characterization of their immunogenicity. Vaccine. 28: 243-55. PMID 19796723 DOI: 10.1016/J.Vaccine.2009.09.089 |
0.305 |
|
| 2009 |
Ng LF, Ojcius DM. Chikungunya fever--re-emergence of an old disease. Microbes and Infection / Institut Pasteur. 11: 1163-4. PMID 19737627 DOI: 10.1016/J.Micinf.2009.09.001 |
0.317 |
|
| 2009 |
Abdul-Sater AA, Koo E, Häcker G, Ojcius DM. Inflammasome-dependent caspase-1 activation in cervical epithelial cells stimulates growth of the intracellular pathogen Chlamydia trachomatis. The Journal of Biological Chemistry. 284: 26789-96. PMID 19648107 DOI: 10.1074/Jbc.M109.026823 |
0.408 |
|
| 2009 |
Coutinho-Silva R, Corrêa G, Sater AA, Ojcius DM. The P2X(7) receptor and intracellular pathogens: a continuing struggle. Purinergic Signalling. 5: 197-204. PMID 19214779 DOI: 10.1007/S11302-009-9130-X |
0.419 |
|
| 2009 |
Jin D, Ojcius DM, Sun D, Dong H, Luo Y, Mao Y, Yan J. Leptospira interrogans induces apoptosis in macrophages via caspase-8- and caspase-3-dependent pathways. Infection and Immunity. 77: 799-809. PMID 19029301 DOI: 10.1128/Iai.00914-08 |
0.326 |
|
| 2009 |
Perfettini JL, Nardacci R, Séror C, Bourouba M, Subra F, Gros L, Manic G, Amendola A, Masdehors P, Rosselli F, Ojcius DM, Auclair C, de Thé H, Gougeon ML, Piacentini M, et al. The tumor suppressor protein PML controls apoptosis induced by the HIV-1 envelope. Cell Death and Differentiation. 16: 298-311. PMID 19023333 DOI: 10.1038/Cdd.2008.158 |
0.325 |
|
| 2008 |
Ying S, Pettengill M, Latham ER, Walch A, Ojcius DM, Häcker G. Premature apoptosis of Chlamydia-infected cells disrupts chlamydial development. The Journal of Infectious Diseases. 198: 1536-44. PMID 18821848 DOI: 10.1086/592755 |
0.388 |
|
| 2008 |
Paschen SA, Christian JG, Vier J, Schmidt F, Walch A, Ojcius DM, Häcker G. Cytopathicity of Chlamydia is largely reproduced by expression of a single chlamydial protease. The Journal of Cell Biology. 182: 117-27. PMID 18625845 DOI: 10.1083/Jcb.200804023 |
0.404 |
|
| 2008 |
Yilmaz O, Yao L, Maeda K, Rose TM, Lewis EL, Duman M, Lamont RJ, Ojcius DM. ATP scavenging by the intracellular pathogen Porphyromonas gingivalis inhibits P2X7-mediated host-cell apoptosis. Cellular Microbiology. 10: 863-75. PMID 18005240 DOI: 10.1111/J.1462-5822.2007.01089.X |
0.41 |
|
| 2007 |
Ying S, Pettengill M, Ojcius DM, Häcker G. Host-Cell Survival and Death During Chlamydia Infection. Current Immunology Reviews. 3: 31-40. PMID 18843378 DOI: 10.2174/157339507779802179 |
0.409 |
|
| 2007 |
Coutinho-Silva R, Monteiro da Cruz C, Persechini PM, Ojcius DM. The role of P2 receptors in controlling infections by intracellular pathogens. Purinergic Signalling. 3: 83-90. PMID 18404421 DOI: 10.1007/S11302-006-9039-6 |
0.399 |
|
| 2007 |
Darville T, Welter-Stahl L, Cruz C, Sater AA, Andrews CW, Ojcius DM. Effect of the purinergic receptor P2X7 on Chlamydia infection in cervical epithelial cells and vaginally infected mice. Journal of Immunology (Baltimore, Md. : 1950). 179: 3707-14. PMID 17785807 DOI: 10.4049/Jimmunol.179.6.3707 |
0.375 |
|
| 2007 |
Cruz CM, Rinna A, Forman HJ, Ventura AL, Persechini PM, Ojcius DM. ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages. The Journal of Biological Chemistry. 282: 2871-9. PMID 17132626 DOI: 10.1074/Jbc.M608083200 |
0.329 |
|
| 2006 |
Ying S, Fischer SF, Pettengill M, Conte D, Paschen SA, Ojcius DM, Häcker G. Characterization of host cell death induced by Chlamydia trachomatis. Infection and Immunity. 74: 6057-66. PMID 16940144 DOI: 10.1128/Iai.00760-06 |
0.391 |
|
| 2006 |
Verbeke P, Welter-Stahl L, Ying S, Hansen J, Häcker G, Darville T, Ojcius DM. Recruitment of BAD by the Chlamydia trachomatis vacuole correlates with host-cell survival. Plos Pathogens. 2: e45. PMID 16710454 DOI: 10.1371/Journal.Ppat.0020045 |
0.392 |
|
| 2006 |
Welter-Stahl L, Ojcius DM, Viala J, Girardin S, Liu W, Delarbre C, Philpott D, Kelly KA, Darville T. Stimulation of the cytosolic receptor for peptidoglycan, Nod1, by infection with Chlamydia trachomatis or Chlamydia muridarum. Cellular Microbiology. 8: 1047-57. PMID 16681844 DOI: 10.1111/J.1462-5822.2006.00686.X |
0.396 |
|
| 2006 |
Yilmaz O, Verbeke P, Lamont RJ, Ojcius DM. Intercellular spreading of Porphyromonas gingivalis infection in primary gingival epithelial cells. Infection and Immunity. 74: 703-10. PMID 16369027 DOI: 10.1128/Iai.74.1.703-710.2006 |
0.383 |
|
| 2005 |
Nagarajan UM, Ojcius DM, Stahl L, Rank RG, Darville T. Chlamydia trachomatis induces expression of IFN-γ-inducible protein 10 and IFN-β independent of TLR2 and TLR4, but largely dependent on MyD88 Journal of Immunology. 175: 450-460. PMID 15972679 DOI: 10.4049/Jimmunol.175.1.450 |
0.392 |
|
| 2005 |
Auger R, Motta I, Benihoud K, Ojcius DM, Kanellopoulos JM. A role for mitogen-activated protein kinaseErk1/2 activation and non-selective pore formation in P2X7 receptor-mediated thymocyte death Journal of Biological Chemistry. 280: 28142-28151. PMID 15937334 DOI: 10.1074/Jbc.M501290200 |
0.326 |
|
| 2005 |
Ojcius DM, Darville T, Bavoil PM. Can chlamyida be stopped? Scientific American. 292: 72-79. PMID 15882024 DOI: 10.1038/Scientificamerican0505-72 |
0.343 |
|
| 2004 |
Jungas T, Verbeke P, Darville T, Ojcius DM. Cell death, BAX activation, and HMGB1 release during infection with Chlamydia Microbes and Infection. 6: 1145-1155. PMID 15488733 DOI: 10.1016/J.Micinf.2004.07.004 |
0.41 |
|
| 2004 |
Byrne GI, Ojcius DM. Chlamydia and apoptosis: Life and death decisions of an intracellular pathogen Nature Reviews Microbiology. 2: 802-808. PMID 15378044 DOI: 10.1038/Nrmicro1007 |
0.404 |
|
| 2004 |
Yilmaz O, Jungas T, Verbeke P, Ojcius DM. Activation of the phosphatidylinositol 3-kinase/Akt pathway contributes to survival of primary epithelial cells infected with the periodontal pathogen Porphyromonas gingivalis Infection and Immunity. 72: 3743-3751. PMID 15213114 DOI: 10.1128/Iai.72.7.3743-3751.2004 |
0.401 |
|
| 2004 |
Darville T, Yedgar S, Krimsky M, Andrews CW, Jungas T, Ojcius DM. Protection against Chlamydia trachomatis infection in vitro and modulation of inflammatory response in vivo by membrane-bound glycosaminoglycans. Microbes and Infection / Institut Pasteur. 6: 369-76. PMID 15050964 DOI: 10.1016/J.Micinf.2003.12.011 |
0.393 |
|
| 2004 |
Mascarell L, Auger R, Alcover A, Ojcius DM, Jungas T, Cadet-Daniel V, Kanellopoulos JM, Truffa-Bachi P. Characterization of a Gene Encoding Two Isoforms of a Mitochondrial Protein Up-regulated by Cyclosporin A in Activated T Cells Journal of Biological Chemistry. 279: 10556-10563. PMID 14684732 DOI: 10.1074/Jbc.M313770200 |
0.313 |
|
| 2003 |
Lupu M, Ojcius DM, Perfettini J, Patry J, Dimicoli JL, Mispelter J. Evidences on sodium ions compartmentalization in biological systems due to pathological states. A noninvasive NMR study Biochimie. 85: 849-861. PMID 14652174 DOI: 10.1016/S0300-9084(03)00122-6 |
0.315 |
|
| 2003 |
Darville T, O'Neill JM, Andrews CW, Nagarajan UM, Stahl L, Ojcius DM. Toll-Like Receptor-2, but Not Toll-Like Receptor-4, Is Essential for Development of Oviduct Pathology in Chlamydial Genital Tract Infection Journal of Immunology. 171: 6187-6197. PMID 14634135 DOI: 10.4049/Jimmunol.171.11.6187 |
0.37 |
|
| 2003 |
Coutinho-Silva R, Stahl L, Raymond MN, Jungas T, Verbeke P, Burnstock G, Darville T, Ojcius DM. Inhibition of chlamydial infectious activity due to P2X7R-dependent phospholipase D activation. Immunity. 19: 403-12. PMID 14499115 DOI: 10.1016/S1074-7613(03)00235-8 |
0.344 |
|
| 2003 |
Boya P, Andreau K, Poncet D, Zamzami N, Perfettini JL, Metivier D, Ojcius DM, Jäättelä M, Kroemer G. Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion Journal of Experimental Medicine. 197: 1323-1334. PMID 12756268 DOI: 10.1084/Jem.20021952 |
0.33 |
|
| 2003 |
Perfettini JL, Ojcius DM, Andrews CW, Korsmeyer SJ, Rank RG, Darville T. Role of proapoptotic BAX in propagation of Chlamydia muridarum (the mouse pneumonitis strain of Chlamydia trachomatis) and the host inflammatory response Journal of Biological Chemistry. 278: 9496-9502. PMID 12509420 DOI: 10.1074/Jbc.M211275200 |
0.399 |
|
| 2002 |
Perfettini JL, Gissot M, Souque P, Ojcius DM. Modulation of apoptosis during infection with Chlamydia Methods in Enzymology. 358: 334-344. PMID 12474397 DOI: 10.1016/S0076-6879(02)58099-X |
0.386 |
|
| 2002 |
Perfettini JL, Reed JC, Israël N, Martinou JC, Dautry-Varsat A, Ojcius DM. Role of Bcl-2 family members in caspase-independent apoptosis during Chlamydia infection Infection and Immunity. 70: 55-61. PMID 11748163 DOI: 10.1128/Iai.70.1.55-61.2002 |
0.367 |
|
| 2000 |
Perfettini JL, Darville T, Gachelin G, Souque P, Huerre M, Dautry-Varsat A, Ojcius DM. Effect of Chlamydia trachomatis infection and subsequent tumor necrosis factor alpha secretion on apoptosis in the murine genital tract Infection and Immunity. 68: 2237-2244. PMID 10722625 DOI: 10.1128/Iai.68.4.2237-2244.2000 |
0.425 |
|
| 1997 |
Ojcius DM, Hellio R, Dautry-Varsat A. Distribution of endosomal, lysosomal, and major histocompatability complex markers in a monocytic cell line infected with Chlamydia psittaci. Infection and Immunity. 65: 2437-2442. PMID 9169786 DOI: 10.1128/Iai.65.6.2437-2442.1997 |
0.328 |
|
| 1991 |
Golstein P, Ojcius DM, Young KDE. Cell death mechanisms and the immune system Immunological Reviews. 29-65. PMID 1937533 DOI: 10.1111/J.1600-065X.1991.Tb00822.X |
0.339 |
|
| 1991 |
Zheng LM, Zychlinsky A, Liu CC, Ojcius DM, Young JDE. Extracellular APT as a trigger for apoptosis or programmed cell death Journal of Cell Biology. 112: 279-288. DOI: 10.1083/Jcb.112.2.279 |
0.336 |
|
| 1990 |
Ojcius DM, Young JD. A role for pore-forming proteins in the pathogenesis by parasites? Parasitology Today. 6: 163-165. PMID 15463330 DOI: 10.1016/0169-4758(90)90340-A |
0.306 |
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