Year |
Citation |
Score |
2023 |
Keeble AH, Wood DP, Howarth M. Design and Evolution of Enhanced Peptide-Peptide Ligation for Modular Transglutaminase Assembly. Bioconjugate Chemistry. PMID 37289810 DOI: 10.1021/acs.bioconjchem.3c00122 |
0.736 |
|
2023 |
Hills RA, Tan TK, Cohen AA, Keeffe JR, Keeble AH, Gnanapragasam PNP, Storm KN, Hill ML, Liu S, Gilbert-Jaramillo J, Afzal M, Napier A, James WS, Bjorkman PJ, Townsend AR, ... Howarth M, et al. Multiviral Quartet Nanocages Elicit Broad Anti-Coronavirus Responses for Proactive Vaccinology. Biorxiv : the Preprint Server For Biology. PMID 36865256 DOI: 10.1101/2023.02.24.529520 |
0.705 |
|
2022 |
Dicks MDJ, Rose LM, Russell RA, Bowman LAH, Graham C, Jimenez-Guardeño JM, Doores KJ, Malim MH, Draper SJ, Howarth M, Biswas S. Modular capsid decoration boosts adenovirus vaccine-induced humoral immunity against SARS-CoV-2. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 35949171 DOI: 10.1016/j.ymthe.2022.08.002 |
0.314 |
|
2021 |
Keeble AH, Yadav VK, Ferla MP, Bauer CC, Chuntharpursat-Bon E, Huang J, Bon RS, Howarth M. DogCatcher allows loop-friendly protein-protein ligation. Cell Chemical Biology. PMID 34324879 DOI: 10.1016/j.chembiol.2021.07.005 |
0.81 |
|
2021 |
Scheu AHA, Lim SYT, Metzner FJ, Mohammed S, Howarth M. NeissLock provides an inducible protein anhydride for covalent targeting of endogenous proteins. Nature Communications. 12: 717. PMID 33514717 DOI: 10.1038/s41467-021-20963-5 |
0.309 |
|
2021 |
Tan TK, Rijal P, Rahikainen R, Keeble AH, Schimanski L, Hussain S, Harvey R, Hayes JWP, Edwards JC, McLean RK, Martini V, Pedrera M, Thakur N, Conceicao C, Dietrich I, ... ... Howarth M, et al. A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses. Nature Communications. 12: 542. PMID 33483491 DOI: 10.1038/s41467-020-20654-7 |
0.714 |
|
2021 |
Buldun CM, Khairil Anuar INA, Howarth M. SnoopLigase-Mediated Peptide-Peptide Conjugation and Purification. Methods in Molecular Biology (Clifton, N.J.). 2208: 13-31. PMID 32856253 DOI: 10.1007/978-1-0716-0928-6_2 |
0.817 |
|
2020 |
Keeble AH, Howarth M. Power to the protein: enhancing and combining activities using the Spy toolbox. Chemical Science. 11: 7281-7291. PMID 33552459 DOI: 10.1039/D0Sc01878C |
0.761 |
|
2020 |
Howarth M, Rahikainen R, Rijal P, Tan T, Draper S, Townsend A, Wu HJ, Bowden T, Andersson AM, Barrett J. Overcoming Symmetry Mismatch in Vaccine Nanoassembly via Spontaneous Amidation. Angewandte Chemie (International Ed. in English). PMID 32886840 DOI: 10.1002/Anie.202009663 |
0.392 |
|
2019 |
Keeble AH, Turkki P, Stokes S, Khairil Anuar INA, Rahikainen R, Hytönen VP, Howarth M. Approaching infinite affinity through engineering of peptide-protein interaction. Proceedings of the National Academy of Sciences of the United States of America. PMID 31822621 DOI: 10.1073/Pnas.1909653116 |
0.77 |
|
2019 |
Khairil Anuar INA, Banerjee A, Keeble AH, Carella A, Nikov GI, Howarth M. Spy&Go purification of SpyTag-proteins using pseudo-SpyCatcher to access an oligomerization toolbox. Nature Communications. 10: 1734. PMID 30988307 DOI: 10.1038/S41467-019-09678-W |
0.773 |
|
2019 |
Andersson AC, Buldun CM, Pattinson DJ, Draper SJ, Howarth M. SnoopLigase peptide-peptide conjugation enables modular vaccine assembly. Scientific Reports. 9: 4625. PMID 30874593 DOI: 10.1038/S41598-019-40985-W |
0.808 |
|
2019 |
Keeble AH, Howarth M. Insider information on successful covalent protein coupling with help from SpyBank. Methods in Enzymology. 617: 443-461. PMID 30784412 DOI: 10.1016/Bs.Mie.2018.12.010 |
0.778 |
|
2018 |
Wieduwild R, Howarth M. Assembling and decorating hyaluronan hydrogels with twin protein superglues to mimic cell-cell interactions. Biomaterials. 180: 253-264. PMID 30053659 DOI: 10.1016/J.Biomaterials.2018.07.020 |
0.775 |
|
2018 |
Bruun TUJ, Andersson AC, Draper SJ, Howarth M. Engineering a Rugged Nanoscaffold To Enhance Plug-and-Display Vaccination. Acs Nano. PMID 30028591 DOI: 10.1021/Acsnano.8B02805 |
0.46 |
|
2018 |
Brune KD, Howarth M. New Routes and Opportunities for Modular Construction of Particulate Vaccines: Stick, Click, and Glue. Frontiers in Immunology. 9: 1432. PMID 29997617 DOI: 10.3389/Fimmu.2018.01432 |
0.785 |
|
2018 |
Buldun CM, Jean J, Bedford MR, Howarth M. SnoopLigase catalyzes peptide-peptide locking and enables solid-phase conjugate isolation. Journal of the American Chemical Society. PMID 29402082 DOI: 10.1021/Jacs.7B13237 |
0.8 |
|
2017 |
Banerjee A, Howarth M. Nanoteamwork: covalent protein assembly beyond duets towards protein ensembles and orchestras. Current Opinion in Biotechnology. 51: 16-23. PMID 29172131 DOI: 10.1016/J.Copbio.2017.10.006 |
0.391 |
|
2017 |
Keeble AH, Banerjee A, Reddington SC, Ferla MP, Howarth M, Khairil Anuar INA. Evolving accelerated amidation by SpyTag/SpyCatcher to analyze membrane dynamics. Angewandte Chemie (International Ed. in English). PMID 29024296 DOI: 10.1002/Anie.201707623 |
0.805 |
|
2017 |
Jacobsen MT, Fairhead M, Fogelstrand P, Howarth M. Amine Landscaping to Maximize Protein-Dye Fluorescence and Ultrastable Protein-Ligand Interaction. Cell Chemical Biology. PMID 28757182 DOI: 10.1016/J.Chembiol.2017.06.015 |
0.742 |
|
2017 |
Leneghan DB, Miura K, Taylor IJ, Li Y, Jin J, Brune KD, Bachmann MF, Howarth M, Long CA, Biswas S. Nanoassembly routes stimulate conflicting antibody quantity and quality for transmission-blocking malaria vaccines. Scientific Reports. 7: 3811. PMID 28630474 DOI: 10.1038/S41598-017-03798-3 |
0.779 |
|
2017 |
Howarth M. Smart superglue in streptococci? The proof is in the pulling. The Journal of Biological Chemistry. 292: 8998-8999. PMID 28550142 DOI: 10.1074/Jbc.H117.777466 |
0.371 |
|
2017 |
Brune K, Buldun C, Li Y, Taylor I, Brod F, Biswas S, Howarth M. Dual plug-and-display synthetic assembly using orthogonal reactive proteins for twin antigen immunization. Bioconjugate Chemistry. PMID 28437083 DOI: 10.1021/Acs.Bioconjchem.7B00174 |
0.775 |
|
2017 |
Gilbert C, Howarth M, Harwood CR, Ellis T. Extracellular self-assembly of functional and tunable protein conjugates from Bacillus subtilis. Acs Synthetic Biology. PMID 28230977 DOI: 10.1021/Acssynbio.6B00292 |
0.428 |
|
2016 |
Bano F, Banerji S, Howarth M, Jackson DG, Richter RP. A single molecule assay to probe monovalent and multivalent bonds between hyaluronan and its key leukocyte receptor CD44 under force. Scientific Reports. 6: 34176. PMID 27679982 DOI: 10.1038/Srep34176 |
0.318 |
|
2016 |
Schoene C, Bennett SP, Howarth M. SpyRings Declassified: A Blueprint for Using Isopeptide-Mediated Cyclization to Enhance Enzyme Thermal Resilience. Methods in Enzymology. 580: 149-67. PMID 27586332 DOI: 10.1016/Bs.Mie.2016.05.004 |
0.77 |
|
2016 |
Schoene C, Bennett SP, Howarth M. SpyRing interrogation: analyzing how enzyme resilience can be achieved with phytase and distinct cyclization chemistries. Scientific Reports. 6: 21151. PMID 26861173 DOI: 10.1038/Srep21151 |
0.799 |
|
2016 |
Veggiani G, Nakamura T, Brenner MD, Gayet RV, Yan J, Robinson CV, Howarth M. Programmable polyproteams built using twin peptide superglues. Proceedings of the National Academy of Sciences of the United States of America. PMID 26787909 DOI: 10.1073/Pnas.1519214113 |
0.805 |
|
2016 |
Brune KD, Leneghan DB, Brian IJ, Ishizuka AS, Bachmann MF, Draper SJ, Biswas S, Howarth M. Plug-and-Display: decoration of Virus-Like Particles via isopeptide bonds for modular immunization. Scientific Reports. 6: 19234. PMID 26781591 DOI: 10.1038/Srep19234 |
0.805 |
|
2016 |
Schoene C, Bennett SP, Howarth M. SpyRing interrogation: Analyzing how enzyme resilience can be achieved with phytase and distinct cyclization chemistries Scientific Reports. 6. DOI: 10.1038/srep21151 |
0.763 |
|
2015 |
Reddington SC, Howarth M. Secrets of a covalent interaction for biomaterials and biotechnology: SpyTag and SpyCatcher. Current Opinion in Chemical Biology. 29: 94-9. PMID 26517567 DOI: 10.1016/J.Cbpa.2015.10.002 |
0.514 |
|
2015 |
Fairhead M, Howarth M. Site-specific biotinylation of purified proteins using BirA. Methods in Molecular Biology (Clifton, N.J.). 1266: 171-84. PMID 25560075 DOI: 10.1007/978-1-4939-2272-7_12 |
0.458 |
|
2014 |
Veggiani G, Zakeri B, Howarth M. Superglue from bacteria: unbreakable bridges for protein nanotechnology. Trends in Biotechnology. 32: 506-12. PMID 25168413 DOI: 10.1016/J.Tibtech.2014.08.001 |
0.486 |
|
2014 |
Fairhead M, Shen D, Chan LK, Lowe ED, Donohoe TJ, Howarth M. Love-Hate ligands for high resolution analysis of strain in ultra-stable protein/small molecule interaction. Bioorganic & Medicinal Chemistry. 22: 5476-86. PMID 25128469 DOI: 10.1016/J.Bmc.2014.07.029 |
0.323 |
|
2014 |
Fairhead M, Veggiani G, Lever M, Yan J, Mesner D, Robinson CV, Dushek O, van der Merwe PA, Howarth M. SpyAvidin hubs enable precise and ultrastable orthogonal nanoassembly. Journal of the American Chemical Society. 136: 12355-63. PMID 25111182 DOI: 10.1021/Ja505584F |
0.397 |
|
2014 |
Schoene C, Fierer JO, Bennett SP, Howarth M. SpyTag/SpyCatcher cyclization confers resilience to boiling on a mesophilic enzyme. Angewandte Chemie (International Ed. in English). 53: 6101-4. PMID 24817566 DOI: 10.1002/Anie.201402519 |
0.78 |
|
2014 |
Fierer JO, Veggiani G, Howarth M. SpyLigase peptide-peptide ligation polymerizes affibodies to enhance magnetic cancer cell capture. Proceedings of the National Academy of Sciences of the United States of America. 111: E1176-81. PMID 24639550 DOI: 10.1073/Pnas.1315776111 |
0.455 |
|
2014 |
Li L, Fierer JO, Rapoport TA, Howarth M. Structural analysis and optimization of the covalent association between SpyCatcher and a peptide Tag. Journal of Molecular Biology. 426: 309-17. PMID 24161952 DOI: 10.1016/J.Jmb.2013.10.021 |
0.455 |
|
2014 |
Fairhead M, Krndija D, Lowe ED, Howarth M. Plug-and-play pairing via defined divalent streptavidins. Journal of Molecular Biology. 426: 199-214. PMID 24056174 DOI: 10.1016/J.Jmb.2013.09.016 |
0.31 |
|
2013 |
Jain J, Veggiani G, Howarth M. Cholesterol loading and ultrastable protein interactions determine the level of tumor marker required for optimal isolation of cancer cells. Cancer Research. 73: 2310-21. PMID 23378340 DOI: 10.1158/0008-5472.Can-12-2956 |
0.334 |
|
2013 |
Koner AL, Krndija D, Hou Q, Sherratt DJ, Howarth M. Hydroxy-terminated conjugated polymer nanoparticles have near-unity bright fraction and reveal cholesterol-dependence of IGF1R nanodomains. Acs Nano. 7: 1137-44. PMID 23330847 DOI: 10.1021/Nn3042122 |
0.627 |
|
2012 |
Liu DS, Phipps WS, Loh KH, Howarth M, Ting AY. Quantum dot targeting with lipoic acid ligase and HaloTag for single-molecule imaging on living cells. Acs Nano. 6: 11080-7. PMID 23181687 DOI: 10.1021/Nn304793Z |
0.767 |
|
2012 |
Zakeri B, Fierer JO, Celik E, Chittock EC, Schwarz-Linek U, Moy VT, Howarth M. Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin. Proceedings of the National Academy of Sciences of the United States of America. 109: E690-7. PMID 22366317 DOI: 10.1073/Pnas.1115485109 |
0.473 |
|
2012 |
Celik E, Zakeri B, Howarth M, Moy VT. An Irreversible Lock to Proteins for Dynamic Force Spectroscopy at the Mammalian Cell Surface Biophysical Journal. 102: 7-8. DOI: 10.1016/J.Bpj.2011.11.3897 |
0.437 |
|
2011 |
Dalchau N, Phillips A, Goldstein LD, Howarth M, Cardelli L, Emmott S, Elliott T, Werner JM. A peptide filtering relation quantifies MHC class I peptide optimization. Plos Computational Biology. 7: e1002144. PMID 22022238 DOI: 10.1371/Journal.Pcbi.1002144 |
0.379 |
|
2011 |
Alakoskela JM, Koner AL, Rudnicka D, Köhler K, Howarth M, Davis DM. Mechanisms for size-dependent protein segregation at immune synapses assessed with molecular rulers. Biophysical Journal. 100: 2865-74. PMID 21689519 DOI: 10.1016/J.Bpj.2011.05.013 |
0.645 |
|
2011 |
Chivers CE, Koner AL, Lowe ED, Howarth M. How the biotin-streptavidin interaction was made even stronger: investigation via crystallography and a chimaeric tetramer. The Biochemical Journal. 435: 55-63. PMID 21241253 DOI: 10.1042/Bj20101593 |
0.62 |
|
2010 |
Chivers CE, Crozat E, Chu C, Moy VT, Sherratt DJ, Howarth M. A streptavidin variant with slower biotin dissociation and increased mechanostability. Nature Methods. 7: 391-3. PMID 20383133 DOI: 10.1038/Nmeth.1450 |
0.303 |
|
2010 |
Zakeri B, Howarth M. Spontaneous intermolecular amide bond formation between side chains for irreversible peptide targeting. Journal of the American Chemical Society. 132: 4526-7. PMID 20235501 DOI: 10.1021/Ja910795A |
0.475 |
|
2009 |
Holm L, Moody P, Howarth M. Electrophilic affibodies forming covalent bonds to protein targets. The Journal of Biological Chemistry. 284: 32906-13. PMID 19759009 DOI: 10.1074/Jbc.M109.034322 |
0.412 |
|
2008 |
Howarth M, Liu W, Puthenveetil S, Zheng Y, Marshall LF, Schmidt MM, Wittrup KD, Bawendi MG, Ting AY. Monovalent, reduced-size quantum dots for imaging receptors on living cells. Nature Methods. 5: 397-9. PMID 18425138 DOI: 10.1038/Nmeth.1206 |
0.596 |
|
2008 |
Howarth M, Ting AY. Imaging proteins in live mammalian cells with biotin ligase and monovalent streptavidin. Nature Protocols. 3: 534-45. PMID 18323822 DOI: 10.1038/Nprot.2008.20 |
0.652 |
|
2008 |
Thirdborough SM, Roddick JS, Radcliffe JN, Howarth M, Stevenson FK, Elliott T. Tapasin shapes immunodominance hierarchies according to the kinetic stability of peptide-MHC class I complexes. European Journal of Immunology. 38: 364-9. PMID 18196518 DOI: 10.1002/Eji.200737832 |
0.4 |
|
2008 |
Liu W, Howarth M, Greytak AB, Zheng Y, Nocera DG, Ting AY, Bawendi MG. Compact biocompatible quantum dots functionalized for cellular imaging. Journal of the American Chemical Society. 130: 1274-84. PMID 18177042 DOI: 10.1021/Ja076069P |
0.596 |
|
2008 |
Howarth M, Ting A. Monovalent streptavidin expression and purification Nature Protocols. DOI: 10.1038/Nprot.2008.81 |
0.536 |
|
2006 |
Howarth M, Chinnapen DJ, Gerrow K, Dorrestein PC, Grandy MR, Kelleher NL, El-Husseini A, Ting AY. A monovalent streptavidin with a single femtomolar biotin binding site. Nature Methods. 3: 267-73. PMID 16554831 DOI: 10.1038/Nmeth861 |
0.582 |
|
2006 |
Howarth M, Ting AY. Giving cells a new sugar-coating. Nature Chemical Biology. 2: 127-8. PMID 16485002 DOI: 10.1038/Nchembio0306-127 |
0.564 |
|
2005 |
Howarth M, Takao K, Hayashi Y, Ting AY. Targeting quantum dots to surface proteins in living cells with biotin ligase. Proceedings of the National Academy of Sciences of the United States of America. 102: 7583-8. PMID 15897449 DOI: 10.1073/Pnas.0503125102 |
0.637 |
|
2005 |
Chen I, Howarth M, Lin W, Ting AY. Site-specific labeling of cell surface proteins with biophysical probes using biotin ligase. Nature Methods. 2: 99-104. PMID 15782206 DOI: 10.1038/Nmeth735 |
0.655 |
|
2004 |
Howarth M, Williams A, Tolstrup AB, Elliott T. Tapasin enhances MHC class I peptide presentation according to peptide half-life. Proceedings of the National Academy of Sciences of the United States of America. 101: 11737-42. PMID 15286279 DOI: 10.1073/Pnas.0306294101 |
0.375 |
|
2004 |
Howarth M, Elliott T. The processing of antigens delivered as DNA vaccines. Immunological Reviews. 199: 27-39. PMID 15233724 DOI: 10.1111/J.0105-2896.2004.00141.X |
0.341 |
|
2002 |
Gao B, Adhikari R, Howarth M, Nakamura K, Gold MC, Hill AB, Knee R, Michalak M, Elliott T. Assembly and antigen-presenting function of MHC class I molecules in cells lacking the ER chaperone calreticulin. Immunity. 16: 99-109. PMID 11825569 DOI: 10.1016/S1074-7613(01)00260-6 |
0.341 |
|
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