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David A. Colby - Publications

Affiliations: 
Chemistry Purdue University, West Lafayette, IN, United States 
Area:
natural product synthesis
Website:
http://www.chem.purdue.edu/people/faculty/faculty.asp?itemID=86
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41/73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Islam B, Colby DA. Transient Formation of Hemiketals from Pentafluoro--diols in the Presence of Alcohols. Journal of Fluorine Chemistry. 270. PMID 37546180 DOI: 10.1016/j.jfluchem.2023.110162  0.75
2022 Khatri HR, Han C, Alkhodier RA, Adam AT, Islam B, Colby DA. Generation of formaldehyde and formaldehyde-d for hydroxymethylations and hydroxydeuteromethylations of difluoroenolates and difluorobenzyl carbanions. Chemical Communications (Cambridge, England). 58: 5490-5493. PMID 35416212 DOI: 10.1039/d2cc01518h  0.74
2021 Sowaileh MF, Alshammari MD, Colby DA. Synthesis of Difluorinated Halohydrins by the Chemoselective Addition of Difluoroenolates to α-Haloketones. Organic Letters. PMID 34124917 DOI: 10.1021/acs.orglett.1c01636  0.803
2020 Adam AT, Fronczek FR, Colby DA. Synthesis of β-Fluoro-α,β-Unsaturated Amides from the Fragmentation of Morpholine 3,3,3-Trifluoropropanamide by Grignard Reagents. Organic Letters. PMID 32181669 DOI: 10.1021/Acs.Orglett.0C00599  0.366
2019 Khatri HR, Han C, Luong E, Pan X, Adam AT, Alshammari MD, Shao Y, Colby DA. Controlling the Cleavage of Carbon-Carbon Bonds to Generate α,α-Difluorobenzyl Carbanions for the Construction of Difluoromethylbenzenes. The Journal of Organic Chemistry. PMID 31449418 DOI: 10.1021/Acs.Joc.9B01595  0.791
2018 Sowaileh MF, Salyer AE, Roy KK, John JP, Woods JR, Doerksen RJ, Hockerman GH, Colby DA. Agonists of the γ-aminobutyric acid type B (GABA) receptor derived from β-hydroxy and β-amino difluoromethyl ketones. Bioorganic & Medicinal Chemistry Letters. PMID 29657102 DOI: 10.1016/J.Bmcl.2018.04.003  0.777
2018 Nguyen AL, Khatri HR, Woods JR, Baldwin CS, Fronczek FR, Colby DA. Magnesium-promoted Additions of Difluoroenolates to Unactivated Imines. The Journal of Organic Chemistry. PMID 29446944 DOI: 10.1021/Acs.Joc.7B03014  0.799
2017 Sowaileh MF, Han C, Hazlitt RA, Kim EH, John JP, Colby DA. Conversion of Methyl Ketones and Methyl Sulfones into α-Deutero-α,α-Difluoromethyl Ketones and α-Deutero-α,α-Difluoromethyl Sulfones in Three Synthetic Steps. Tetrahedron Letters. 58: 396-400. PMID 28943667 DOI: 10.1016/J.Tetlet.2016.12.018  0.752
2017 Sowaileh MF, Hazlitt RA, Colby DA. Application of the Pentafluorosulfanyl Group as a Bioisosteric Replacement. Chemmedchem. PMID 28782186 DOI: 10.1002/Cmdc.201700356  0.775
2017 Hazlitt RA, Tran QL, Sowaileh MF, Colby DA. Generation of Magnesium Pentafluoropropen-2-olate from Hexafluoroisopropanol and Synthesis of 2,2,4,4,4-Pentafluoro-3,3-dihydroxyketones. The Journal of Organic Chemistry. PMID 28107014 DOI: 10.1021/Acs.Joc.6B02863  0.789
2016 Gunasekara DC, Zheng MM, Mojtahed T, Woods JR, Fandy TE, Riofski MV, Glackin CA, Hassan HE, Kirshner J, Colby DA. 15-Methylene-Eburnamonine Kills Leukemic Stem Cells and Reduces Engraftment in a Humanized Bone Marrow Xenograft Mouse Model of Leukemia. Chemmedchem. PMID 27677525 DOI: 10.1002/Cmdc.201600334  0.751
2016 Hazlitt RA, John JP, Tran QL, Colby DA. Optimized Synthesis of a Pentafluoro-gem-diol and Conversion to a CF2Br-Glucopyranose through Trifluoroacetate-Release and Halogenation. Tetrahedron Letters. 57: 1906-1908. PMID 27182091 DOI: 10.1016/J.Tetlet.2016.03.064  0.363
2015 Barrios FJ, Springer BC, Hazlitt RA, Colby DA. Effect of Substituents and Stability of Transient Aluminum-Aminals in the Presence of Nucleophiles. Synthesis. 47: 175-180. PMID 28250502 DOI: 10.1055/S-0034-1379635  0.794
2015 Glauber KM, Dana CE, Park SS, Colby DA, Noro Y, Fujisawa T, Chamberlin AR, Steele RE. A small molecule screen identifies a novel compound that induces a homeotic transformation in Hydra. Development (Cambridge, England). 142: 2081. PMID 26015540 DOI: 10.1242/dev.126235  0.483
2015 Barrios FJ, Springer BC, Hazlitt RA, Colby DA. Effect of Substituents and Stability of Transient Aluminum-Aminals in the Presence of Nucleophiles Synthesis (Germany). 47: 175-180. DOI: 10.1055/s-0034-1379635  0.771
2013 Glauber KM, Dana CE, Park SS, Colby DA, Noro Y, Fujisawa T, Chamberlin AR, Steele RE. A small molecule screen identifies a novel compound that induces a homeotic transformation in Hydra. Development (Cambridge, England). 140: 4788-96. PMID 24255098 DOI: 10.1242/Dev.094490  0.532
2013 Woods JR, Riofski MV, Zheng MM, O'Banion MA, Mo H, Kirshner J, Colby DA. Synthesis of 15-methylene-eburnamonine from (+)-vincamine, evaluation of anticancer activity, and investigation of mechanism of action by quantitative NMR. Bioorganic & Medicinal Chemistry Letters. 23: 5865-9. PMID 24055047 DOI: 10.1016/J.Bmcl.2013.08.095  0.795
2013 Barrios FJ, Springer BC, Colby DA. Control of transient aluminum-aminals for masking and unmasking reactive carbonyl groups. Organic Letters. 15: 3082-5. PMID 23730896 DOI: 10.1021/Ol401265A  0.791
2013 Han C, Salyer AE, Kim EH, Jiang X, Jarrard RE, Powers MS, Kirchhoff AM, Salvador TK, Chester JA, Hockerman GH, Colby DA. Evaluation of difluoromethyl ketones as agonists of the γ-aminobutyric acid type B (GABAB) receptor. Journal of Medicinal Chemistry. 56: 2456-65. PMID 23428109 DOI: 10.1021/Jm301805E  0.766
2013 Riofski MV, Hart AD, Colby DA. Amidinate salt of hexafluoroacetone hydrate for the preparation of fluorinated compounds by the release of trifluoroacetate. Organic Letters. 15: 208-11. PMID 23240844 DOI: 10.1021/Ol303291X  0.785
2013 Woods JR, Mo H, Bieberich AA, Alavanja T, Colby DA. Amino-derivatives of the sesquiterpene lactone class of natural products as prodrugs Medchemcomm. 4: 27-33. DOI: 10.1039/C2Md20172K  0.412
2012 Zheng M, Riofski MV, Woods J, Colby DA, Kirshner J. Abstract 1984: Nature's pharmacy: eburnamonine and its derivative as therapeutics against brain tumors Cancer Research. 72: 1984-1984. DOI: 10.1158/1538-7445.Am2012-1984  0.751
2012 Han C, Kim EH, Colby DA. Cleaving carbon-carbon bonds by the release of trifluoroacetate to remodel molecules and assemble fluorinated structures Synlett. 23: 1559-1563. DOI: 10.1055/S-0031-1291156  0.546
2011 Woods JR, Mo H, Bieberich AA, Alavanja T, Colby DA. Fluorinated amino-derivatives of the sesquiterpene lactone, parthenolide, as (19)f NMR probes in deuterium-free environments. Journal of Medicinal Chemistry. 54: 7934-41. PMID 22029741 DOI: 10.1021/Jm201114T  0.362
2011 John JP, Colby DA. Synthesis of α-halo-α,α-difluoromethyl ketones by a trifluoroacetate release/halogenation protocol. The Journal of Organic Chemistry. 76: 9163-8. PMID 21995668 DOI: 10.1021/Jo2017179  0.442
2011 Riofski MV, John JP, Zheng MM, Kirshner J, Colby DA. Exploiting the facile release of trifluoroacetate for the α-methylenation of the sterically hindered carbonyl groups on (+)-sclareolide and (-)-eburnamonine. The Journal of Organic Chemistry. 76: 3676-83. PMID 21491928 DOI: 10.1021/Jo102114F  0.805
2011 Han C, Kim EH, Colby DA. Cleavage of carbon-carbon bonds through the mild release of trifluoroacetate: generation of α,α-difluoroenolates for aldol reactions. Journal of the American Chemical Society. 133: 5802-5. PMID 21443226 DOI: 10.1021/Ja202213F  0.774
2011 Gunn EJ, Williams JT, Huynh DT, Iannotti MJ, Han C, Barrios FJ, Kendall S, Glackin CA, Colby DA, Kirshner J. The natural products parthenolide and andrographolide exhibit anti-cancer stem cell activity in multiple myeloma. Leukemia & Lymphoma. 52: 1085-97. PMID 21417826 DOI: 10.3109/10428194.2011.555891  0.758
2011 Williams JT, Gunn EJ, Huynh DT, Iannotti MJ, Glackin CA, Colby DA, Kirshner J. Abstract 3401: The natural products, parthenolide and andrographolide, exhibit anti-cancer stem cell activity in multiple myeloma Cancer Research. 71: 3401-3401. DOI: 10.1158/1538-7445.Am2011-3401  0.309
2010 Barrios FJ, Zhang X, Colby DA. Dialkylaluminum N,O-dimethylhydroxylamine complex as a reagent to mask reactive carbonyl groups in situ from nucleophiles. Organic Letters. 12: 5588-91. PMID 21038923 DOI: 10.1021/Ol102495V  0.783
2010 Huynh DT, Iannotti MJ, Gunn EJ, Han C, Barrios FJ, Colby DA, Kirshner J. Abstract 4292: Parthenolide and structurally related natural products as anti-cancer stem cell agents: A new era in treatment of multiple myeloma Cancer Research. 70: 4292-4292. DOI: 10.1158/1538-7445.Am10-4292  0.759
2009 Han C, Barrios FJ, Riofski MV, Colby DA. Semisynthetic derivatives of sesquiterpene lactones by palladium-catalyzed arylation of the alpha-methylene-gamma-lactone substructure. The Journal of Organic Chemistry. 74: 7176-9. PMID 19697954 DOI: 10.1021/Jo901533E  0.753
2009 Ishikawa H, Colby DA, Seto S, Va P, Tam A, Kakei H, Rayl TJ, Hwang I, Boger DL. Total synthesis of vinblastine, vincristine, related natural products, and key structural analogues. Journal of the American Chemical Society. 131: 4904-16. PMID 19292450 DOI: 10.1021/Ja809842B  0.517
2009 Ishikawa H, Colby DA, Seto S, Va P, Tam A, Kakei H, Rayl TJ, Hwang I, Boger DL. Synthesis of Vinblastine Synfacts. 2009: 944-944. DOI: 10.1055/S-0029-1217622  0.468
2008 Ishikawa H, Colby DA, Boger DL. Direct coupling of catharanthine and vindoline to provide vinblastine: total synthesis of (+)- and ent-(-)-vinblastine. Journal of the American Chemical Society. 130: 420-1. PMID 18081297 DOI: 10.1021/Ja078192M  0.48
2007 Boger D, Lawhorn B, Boga S, Wolkenberg S, Colby D, Gauss C, Swingle M, Amable L, Honkanen R. Synthesis of Cytostatin Synfacts. 2007: 0456-0456. DOI: 10.1055/S-2007-968390  0.701
2006 Lawhorn BG, Boga SB, Wolkenberg SE, Colby DA, Gauss CM, Swingle MR, Amable L, Honkanen RE, Boger DL. Total synthesis and evaluation of cytostatin, its C10-C11 diastereomers, and additional key analogues: impact on PP2A inhibition. Journal of the American Chemical Society. 128: 16720-32. PMID 17177422 DOI: 10.1021/Ja066477D  0.713
2006 Colby DA, Chamberlin AR. Pharmacophore identification: the case of the ser/thr protein phosphatase inhibitors. Mini Reviews in Medicinal Chemistry. 6: 657-65. PMID 16787376 DOI: 10.2174/138955706777435715  0.503
2003 Colby DA, Liu W, Sheppeck JE, Huang HB, Nairn AC, Chamberlin AR. A new model of the tautomycin-PP1 complex that is not analogous to the corresponding okadaic acid structure. Bioorganic & Medicinal Chemistry Letters. 13: 1601-5. PMID 12699764 DOI: 10.1016/S0960-894X(03)00106-9  0.541
2003 Liu W, Sheppeck JE, Colby DA, Huang HB, Nairn AC, Chamberlin AR. The selective inhibition of phosphatases by natural toxins: the anhydride domain of tautomycin is not a primary factor in controlling PP1/PP2A selectivity. Bioorganic & Medicinal Chemistry Letters. 13: 1597-600. PMID 12699763 DOI: 10.1016/S0960-894X(03)00105-7  0.555
2002 Romero-Ortega M, Colby DA, Olivo HF. Synthesis of the C10-C17 fragment of aurisides and callipeltosides Tetrahedron Letters. 43: 6439-6441. DOI: 10.1016/S0040-4039(02)01340-0  0.317
Low-probability matches (unlikely to be authored by this person)
1999 Olivo HF, Colby DA, Hemenway MS. Syntheses of New Open-Ring and homo-Epibatidine Analogues from Tropinone. The Journal of Organic Chemistry. 64: 4966-4968. PMID 11674583 DOI: 10.1021/Jo990097B  0.3
2015 Brown KM, Roy KK, Hockerman GH, Doerksen RJ, Colby DA. Activation of the γ-Aminobutyric Acid Type B (GABAB) Receptor by Agonists and Positive Allosteric Modulators. Journal of Medicinal Chemistry. PMID 25856547 DOI: 10.1021/Jm5018913  0.289
2013 Zheng MM, Harris B, Woods J, Colby D, Kirshner J. Abstract B30: 15-Methylene-Eburnamonine: A preventative agent against breast to brain metastases by targeting circulating tumor cells and cancer stem cells through induction of oxidative stress Cancer Prevention Research. 6. DOI: 10.1158/1940-6215.Prev-13-B30  0.287
2007 Lash TD, Colby DA, Idate AS, Davis RN. Fulvene dialdehyde strategy for adj-dicarbaporphyrinoid synthesis: preparation of a 22-carbaazuliporphyrin. Journal of the American Chemical Society. 129: 13800-1. PMID 17944474 DOI: 10.1021/Ja076414A  0.277
2010 Mo H, Balko KM, Colby DA. A practical deuterium-free NMR method for the rapid determination of 1-octanol/water partition coefficients of pharmaceutical agents. Bioorganic & Medicinal Chemistry Letters. 20: 6712-5. PMID 20864340 DOI: 10.1016/J.Bmcl.2010.08.145  0.272
2012 Lash TD, Lammer AD, Idate AS, Colby DA, White K. Preparation of azulene-derived fulvenedialdehydes and their application to the synthesis of stable adj-dicarbaporphyrinoids. The Journal of Organic Chemistry. 77: 2368-81. PMID 22288783 DOI: 10.1021/Jo2026977  0.267
2003 Lash TD, Colby DA, Ferrence GM. Further Studies on the Synthesis of meso-Tetraarylazuliporphyrins under Lindsey-Rothemund Reaction Conditions and Their Conversion into Benzocarbaporphyrins European Journal of Organic Chemistry. 4533-4548. DOI: 10.1002/Ejoc.200300530  0.26
2012 Colby DA, Tsai AS, Bergman RG, Ellman JA. Rhodium catalyzed chelation-assisted C-H bond functionalization reactions. Accounts of Chemical Research. 45: 814-25. PMID 22148885 DOI: 10.1021/Ar200190G  0.251
2010 Colby DA, Bergman RG, Ellman JA. Rhodium-catalyzed C-C bond formation via heteroatom-directed C-H bond activation. Chemical Reviews. 110: 624-55. PMID 19438203 DOI: 10.1021/Cr900005N  0.228
2007 Mohrig JR, Hammond CN, Colby DA. On the successful use of inquiry-driven experiments in the organic chemistry laboratory Journal of Chemical Education. 84: 992-998. DOI: 10.1021/Ed084P992  0.227
2015 Fandy TE, Abdallah I, Khayat M, Colby DA, Hassan HE. In vitro characterization of transport and metabolism of the alkaloids: vincamine, vinpocetine and eburnamonine. Cancer Chemotherapy and Pharmacology. PMID 26666648 DOI: 10.1007/S00280-015-2924-3  0.225
2016 Thorlton J, Ahmed A, Colby DA. Energy Drinks: Implications for the Breastfeeding Mother. McN. the American Journal of Maternal Child Nursing. PMID 26909852 DOI: 10.1097/Nmc.0000000000000228  0.22
2020 Alshammari MD, Kucheryavy PV, Ashpole NM, Colby DA. Synthesis, biological evaluation, and NMR studies of 3-fluorinated derivatives of 3',4',5'-trihydroxyflavone and 3',4',5'-trimethoxyflavone. Bioorganic & Medicinal Chemistry Letters. 32: 127720. PMID 33259925 DOI: 10.1016/j.bmcl.2020.127720  0.22
2009 Lash TD, El-Beck JA, Colby DA. Synthesis of a tetraazulene porphodimethene analogue. The Journal of Organic Chemistry. 74: 8830-3. PMID 19908914 DOI: 10.1021/Jo901959K  0.218
2014 Thorlton J, Colby DA, Devine P. Proposed actions for the US Food and Drug Administration to implement to minimize adverse effects associated with energy drink consumption. American Journal of Public Health. 104: 1175-80. PMID 24832439 DOI: 10.2105/Ajph.2014.301967  0.218
2002 Colby DA, Lash TD. Adaptation of the Rothemund reaction for carbaporphyrin synthesis: preparation of meso-tetraphenylazuliporphyrin and related benzocarbaporphyrins. Chemistry (Weinheim An Der Bergstrasse, Germany). 8: 5397-402. PMID 12561311 DOI: 10.1002/1521-3765(20021202)8:23<5397::Aid-Chem5397>3.0.Co;2-D  0.207
2002 Colby DA, Lash TD. Calix[4]azulene. The Journal of Organic Chemistry. 67: 1031-3. PMID 11856059 DOI: 10.1021/Jo0110101  0.205
2008 Colby DA, Bergman RG, Ellman JA. Synthesis of dihydropyridines and pyridines from imines and alkynes via C-H activation. Journal of the American Chemical Society. 130: 3645-51. PMID 18302381 DOI: 10.1021/Ja7104784  0.198
2004 Lash TD, Colby DA, Graham SR, Chaney ST. Synthesis, spectroscopy, and reactivity of meso-unsubstituted azuliporphyrins and their heteroanalogues. Oxidative ring contractions to carba-, oxacarba-, thiacarba-, and selenacarbaporphyrins. The Journal of Organic Chemistry. 69: 8851-64. PMID 15575767 DOI: 10.1021/Jo0402531  0.196
2017 Thorlton J, Colby DA. Energy Drink Adverse Effects: What Is Being Done to Protect Public Health? Western Journal of Nursing Research. 193945917731994. PMID 28914182 DOI: 10.1177/0193945917731994  0.193
2002 Graham SR, Colby DA, Lash TD. An azulene analogue of the tripyrranes and carbaporphyrinoids therefrom. Angewandte Chemie (International Ed. in English). 41: 1371-4. PMID 19750768 DOI: 10.1002/1521-3773(20020415)41:8<1371::Aid-Anie1371>3.0.Co;2-Q  0.181
2011 Crimmin MR, Colby DA, Ellman JA, Bergman RG. Synthesis and coordination chemistry of tri-substituted benzamidrazones. Dalton Transactions (Cambridge, England : 2003). 40: 514-22. PMID 21109860 DOI: 10.1039/C0Dt01267J  0.172
2004 Lash TD, Colby DA, Szczepura LF. New riches in carbaporphyrin chemistry: silver and gold organometallic complexes of benzocarbaporphyrins. Inorganic Chemistry. 43: 5258-67. PMID 15310203 DOI: 10.1021/Ic0400540  0.148
2022 Alkhodier RA, Mishra SK, Doerksen RJ, Colby DA. Comparison of Conformational Analyses of Naturally Occurring Flavonoid--Glycosides with Unnatural Flavonoid-CF-Glycosides Using Molecular Modeling. Journal of Chemical Information and Modeling. 63: 375-386. PMID 36512328 DOI: 10.1021/acs.jcim.2c01147  0.147
2015 Lash TD, Colby DA, El-Beck JA, AbuSalim DI, Ferrence GM. Preparation, Structural Characterization, Assessment of Potential Antiaromaticity and Metalation of 21-Oxyazuliporphyrins. Inorganic Chemistry. 54: 9174-87. PMID 26325126 DOI: 10.1021/Acs.Inorgchem.5B01587  0.132
2003 Lash TD, Colby DA, Graham SR, Ferrence GM, Szczepura LF. Organometallic chemistry of azuliporphyrins: synthesis, spectroscopy, electrochemistry, and structural characterization of nickel(II), palladium(II), and platinum(II) complexes of azuliporphyrins. Inorganic Chemistry. 42: 7326-38. PMID 14577805 DOI: 10.1021/Ic030166B  0.128
2006 Colby DA, Bergman RG, Ellman JA. Stereoselective alkylation of alpha,beta-unsaturated imines via C-H bond activation. Journal of the American Chemical Society. 128: 5604-5. PMID 16637605 DOI: 10.1021/Ja0584931  0.126
2004 Lash TD, Rasmussen JM, Bergman KM, Colby DA. Carbaporphyrinoid chemistry has a silver lining! silver(III) oxybenzi-, oxynaphthi-, tropi-, and benzocarbaporphyrins. Organic Letters. 6: 549-52. PMID 14961620 DOI: 10.1021/Ol0363265  0.122
2024 Islam B, Sulochana SP, Colby DA. Synthesis of α,α-Difluoro-β-amino Ketones from -Boc-α-Amidosulfones and Pentafluoro--diols. The Journal of Organic Chemistry. PMID 38606727 DOI: 10.1021/acs.joc.3c02181  0.12
2004 Colby DA, Ferrence GM, Lash TD. Oxidative metalation of azuliporphyrins with copper(II) salts: formation of a porphyrin analogue system with a unique fully conjugated nonaromatic azulene subunit. Angewandte Chemie (International Ed. in English). 43: 1346-9. PMID 15368402 DOI: 10.1002/Anie.200353189  0.079
2003 Feldhaus MJ, Siegel RW, Opresko LK, Coleman JR, Feldhaus JM, Yeung YA, Cochran JR, Heinzelman P, Colby D, Swers J, Graff C, Wiley HS, Wittrup KD. Flow-cytometric isolation of human antibodies from a nonimmune Saccharomyces cerevisiae surface display library. Nature Biotechnology. 21: 163-70. PMID 12536217 DOI: 10.1038/Nbt785  0.066
2013 Colby DA, Shifren K. Optimism, mental health, and quality of life: a study among breast cancer patients. Psychology, Health & Medicine. 18: 10-20. PMID 22690751 DOI: 10.1080/13548506.2012.686619  0.031
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