| Year |
Citation |
Score |
| 2024 |
Min J, Keswani T, LaHood NA, Lytle IR, Marini-Rapoport O, Andrieux L, Sneed SL, Edwards LL, Petrovich RM, Perera L, Pomés A, Pedersen LC, Patil SU, Mueller GA. Design of an Ara h 2 hypoallergen from conformational epitopes. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. PMID 38168500 DOI: 10.1111/cea.14433 |
0.48 |
|
| 2023 |
Kirby TW, Gabel SA, DeRose EF, Perera L, Krahn JM, Pedersen LC, London RE. Targeting the Structural Maturation Pathway of HIV-1 Reverse Transcriptase. Biomolecules. 13. PMID 38002285 DOI: 10.3390/biom13111603 |
0.504 |
|
| 2023 |
Min J, Foo ACY, Gabel SA, Perera L, DeRose EF, Pomés A, Pedersen LC, Mueller GA. Structural and ligand binding analysis of the pet allergens Can f 1 and Fel d 7. Frontiers in Allergy. 4: 1133412. PMID 36960093 DOI: 10.3389/falgy.2023.1133412 |
0.473 |
|
| 2021 |
Foo ACY, Thompson PM, Chen SH, Jadi R, Lupo B, DeRose EF, Arora S, Placentra VC, Premkumar L, Perera L, Pedersen LC, Martin N, Mueller GA. The mosquito protein AEG12 displays both cytolytic and antiviral properties via a common lipid transfer mechanism. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33688047 DOI: 10.1073/pnas.2019251118 |
0.474 |
|
| 2020 |
Duff MR, Gabel SA, Pedersen LC, DeRose EF, Krahn JM, Howell EE, London RE. The structural basis for NSAID inhibition of human dihydrofolate reductase. Journal of Medicinal Chemistry. PMID 32658475 DOI: 10.1021/Acs.Jmedchem.0C00546 |
0.34 |
|
| 2019 |
Pedersen LC, Inoue K, Kim S, Perera L, Shaw ND. A ubiquitin-like domain is required for stabilizing the N-terminal ATPase module of human SMCHD1. Communications Biology. 2: 255. PMID 31925095 DOI: 10.1038/s42003-019-0499-y |
0.502 |
|
| 2019 |
Kim K, Min J, Kirby TW, Gabel SA, Pedersen LC, London RE. Ligand binding characteristics of the Ku80 von Willebrand domain. Dna Repair. 85: 102739. PMID 31733588 DOI: 10.1016/J.Dnarep.2019.102739 |
0.406 |
|
| 2019 |
Kaminski AM, Chiruvella KK, Ramsden DA, Kunkel TA, Bebenek K, Pedersen LC. Unexpected behavior of DNA polymerase Mu opposite template 8-oxo-7,8-dihydro-2'-guanosine. Nucleic Acids Research. PMID 31435651 DOI: 10.2210/Pdb6P1R/Pdb |
0.367 |
|
| 2019 |
Pedersen LC, Inoue K, Kim S, Perera L, Shaw ND. A ubiquitin-like domain is required for stabilizing the N-terminal ATPase module of human SMCHD1. Communications Biology. 2: 255. PMID 31312724 DOI: 10.1038/s42003-019-0499-y |
0.502 |
|
| 2018 |
Kaminski AM, Tumbale PP, Schellenberg MJ, Williams RS, Williams JG, Kunkel TA, Pedersen LC, Bebenek K. Structures of DNA-bound human ligase IV catalytic core reveal insights into substrate binding and catalysis. Nature Communications. 9: 2642. PMID 29980672 DOI: 10.1038/S41467-018-05024-8 |
0.4 |
|
| 2018 |
Kirby TW, Pedersen LC, Gabel SA, Gassman NR, London RE. Variations in Nuclear Localization Strategies Among Pol X Family Enzymes. Traffic (Copenhagen, Denmark). PMID 29931796 DOI: 10.1111/Tra.12600 |
0.402 |
|
| 2018 |
Min J, Perera L, Krahn JM, Jewell CM, Moon AF, Cidlowski JA, Pedersen LC. Probing Dominant Negative Behavior of Glucocorticoid Receptor β through a Hybrid Structural and Biochemical Approach. Molecular and Cellular Biology. PMID 29437838 DOI: 10.1128/Mcb.00453-17 |
0.582 |
|
| 2017 |
Shizu R, Min J, Sobhany M, Pedersen LC, Mutoh S, Negishi M. Interaction of the phosphorylated DNA-binding domain in nuclear receptor CAR with its ligand binding domain regulates CAR activation. The Journal of Biological Chemistry. PMID 29133527 DOI: 10.1074/Jbc.M117.806604 |
0.35 |
|
| 2017 |
Kim K, Pedersen LC, Kirby TW, DeRose EF, London RE. Characterization of the APLF FHA-XRCC1 phosphopeptide interaction and its structural and functional implications. Nucleic Acids Research. PMID 29059378 DOI: 10.1093/Nar/Gkx941 |
0.387 |
|
| 2017 |
Moon AF, Pryor JM, Ramsden DA, Kunkel TA, Bebenek K, Pedersen LC. Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme polymerase Mu. Nucleic Acids Research. 45: 9138-9148. PMID 28911097 DOI: 10.1093/Nar/Gkx527 |
0.42 |
|
| 2017 |
Jamsen JA, Beard WA, Pedersen LC, Shock DD, Moon AF, Krahn JM, Bebenek K, Kunkel TA, Wilson SH. Time-lapse crystallography snapshots of a double-strand break repair polymerase in action. Nature Communications. 8: 253. PMID 28811466 DOI: 10.1038/S41467-017-00271-7 |
0.338 |
|
| 2017 |
Gabel SA, Duff MR, Pedersen LC, DeRose EF, Krahn JM, Howell EE, London RE. A structural basis for biguanide activity. Biochemistry. PMID 28766937 DOI: 10.1021/Acs.Biochem.7B00619 |
0.344 |
|
| 2017 |
Pham P, Afif SA, Shimoda M, Maeda K, Sakaguchi N, Pedersen LC, Goodman MF. Activation-induced deoxycytidine deaminase: Structural basis for favoring WRC hot motif specificities unique among APOBEC family members. Dna Repair. 54: 8-12. PMID 28388461 DOI: 10.1016/J.Dnarep.2017.03.007 |
0.326 |
|
| 2017 |
Xu Y, Moon AF, Xu S, Krahn JM, Liu J, Pedersen LC. Structure Based Substrate Specificity Analysis of Heparan Sulfate 6-O-Sulfotransferases. Acs Chemical Biology. 12: 73-82. PMID 28103688 DOI: 10.1021/Acschembio.6B00841 |
0.411 |
|
| 2016 |
Batra VK, Beard WA, Pedersen LC, Wilson SH. Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism. Structure (London, England : 1993). PMID 27642161 DOI: 10.1016/J.Str.2016.08.006 |
0.381 |
|
| 2016 |
Pham P, Afif SA, Shimoda M, Maeda K, Sakaguchi N, Pedersen LC, Goodman MF. Structural analysis of the activation-induced deoxycytidine deaminase required in immunoglobulin diversification. Dna Repair. 43: 48-56. PMID 27258794 DOI: 10.1016/J.Dnarep.2016.05.029 |
0.43 |
|
| 2016 |
Moon AF, Krahn JM, Lu X, Cuneo MJ, Pedersen LC. Structural characterization of the virulence factor Sda1 nuclease from Streptococcus pyogenes. Nucleic Acids Research. PMID 26969731 DOI: 10.1093/Nar/Gkw143 |
0.352 |
|
| 2016 |
Zheng X, Pedersen LC, Gabel SA, Mueller GA, DeRose EF, London RE. Unfolding the HIV-1 reverse transcriptase RNase H domain - how to lose a molecular tug-of-war. Nucleic Acids Research. PMID 26773054 DOI: 10.1093/Nar/Gkv1538 |
0.345 |
|
| 2016 |
Mueller G, Randall TA, Glesner J, Pedersen L, Perera L, Edwards LL, DeRose E, Chapman MD, London R, Pomés A. Structural, Serological, and Genomic Analyses of the Major Mite Allergen Der p 23 The Journal of Allergy and Clinical Immunology. 137. DOI: 10.1016/J.Jaci.2015.12.1014 |
0.507 |
|
| 2015 |
Mueller GA, Randall TA, Glesner J, Pedersen LC, Perera L, Edwards LL, DeRose EF, Chapman MD, London RE, Pomés A. Serological, genomic, and structural analyses of the major mite allergen Der p 23. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. PMID 26602749 DOI: 10.1111/Cea.12680 |
0.534 |
|
| 2015 |
Kirby TW, Gassman NR, Smith CE, Pedersen LC, Gabel SA, Sobhany M, Wilson SH, London RE. Nuclear Localization of the DNA Repair Scaffold XRCC1: Uncovering the Functional Role of a Bipartite NLS. Scientific Reports. 5: 13405. PMID 26304019 DOI: 10.1038/Srep13405 |
0.378 |
|
| 2015 |
Moon AF, Gosavi RA, Kunkel TA, Pedersen LC, Bebenek K. Creative template-dependent synthesis by human polymerase mu. Proceedings of the National Academy of Sciences of the United States of America. 112: E4530-6. PMID 26240373 DOI: 10.1073/Pnas.1505798112 |
0.383 |
|
| 2015 |
Pomés A, Chruszcz M, Gustchina A, Minor W, Mueller GA, Pedersen LC, Wlodawer A, Chapman MD. 100 Years later: Celebrating the contributions of x-ray crystallography to allergy and clinical immunology. The Journal of Allergy and Clinical Immunology. 136: 29-37.e10. PMID 26145985 DOI: 10.1016/J.Jaci.2015.05.016 |
0.331 |
|
| 2015 |
Mueller GA, Pedersen LC, Glesner J, Edwards LL, Zakzuk J, London RE, Arruda LK, Chapman MD, Caraballo L, Pomés A. Analysis of glutathione S-transferase allergen cross-reactivity in a North American population: Relevance for molecular diagnosis. The Journal of Allergy and Clinical Immunology. PMID 25930195 DOI: 10.1016/J.Jaci.2015.03.015 |
0.328 |
|
| 2015 |
Mueller G, Pedersen L, Glesner J, Edwards LL, Zakzuk J, London R, Arruda LKP, Chapman MD, Caraballo L, Pomes A. Analysis of GST Allergen Cross-Reactivity in a North American Population for Molecular Diagnosis The Journal of Allergy and Clinical Immunology. 135. DOI: 10.1016/J.Jaci.2014.12.1545 |
0.312 |
|
| 2014 |
Moon AF, Gaudu P, Pedersen LC. Structural characterization of the virulence factor nuclease A from Streptococcus agalactiae Acta Crystallographica Section D: Biological Crystallography. 70: 2937-2949. PMID 25372684 DOI: 10.1107/S1399004714019725 |
0.399 |
|
| 2014 |
Bebenek K, Pedersen LC, Kunkel TA. Structure-function studies of DNA polymerase λ. Biochemistry. 53: 2781-92. PMID 24716527 DOI: 10.1021/Bi4017236 |
0.367 |
|
| 2014 |
Hewitt SC, Li L, Grimm SA, Winuthayanon W, Hamilton KJ, Pockette B, Rubel CA, Pedersen LC, Fargo D, Lanz RB, DeMayo FJ, Schütz G, Korach KS. Novel DNA motif binding activity observed in vivo with an estrogen receptor α mutant mouse. Molecular Endocrinology (Baltimore, Md.). 28: 899-911. PMID 24713037 DOI: 10.1210/Me.2014-1051 |
0.366 |
|
| 2014 |
Mueller GA, Ankney JA, Glesner J, Khurana T, Edwards LL, Pedersen LC, Perera L, Slater JE, Pomés A, London RE. Characterization of an anti-Bla g 1 scFv: epitope mapping and cross-reactivity. Molecular Immunology. 59: 200-7. PMID 24667070 DOI: 10.1016/J.Molimm.2014.02.003 |
0.529 |
|
| 2014 |
Liu C, Sheng J, Krahn JM, Perera L, Xu Y, Hsieh PH, Dou W, Liu J, Pedersen LC. Molecular mechanism of substrate specificity for heparan sulfate 2-O-sulfotransferase. The Journal of Biological Chemistry. 289: 13407-18. PMID 24652287 DOI: 10.1074/Jbc.M113.530535 |
0.563 |
|
| 2014 |
Mueller GA, Maleki SJ, Pedersen LC. The molecular basis of peanut allergy. Current Allergy and Asthma Reports. 14: 429. PMID 24633613 DOI: 10.1007/S11882-014-0429-5 |
0.311 |
|
| 2014 |
Zheng X, Pedersen LC, Gabel SA, Mueller GA, Cuneo MJ, DeRose EF, Krahn JM, London RE. Selective unfolding of one Ribonuclease H domain of HIV reverse transcriptase is linked to homodimer formation. Nucleic Acids Research. 42: 5361-77. PMID 24574528 DOI: 10.1093/Nar/Gku143 |
0.344 |
|
| 2014 |
Moon AF, Pryor JM, Ramsden DA, Kunkel TA, Bebenek K, Pedersen LC. Sustained active site rigidity during synthesis by human DNA polymerase μ. Nature Structural & Molecular Biology. 21: 253-60. PMID 24487959 DOI: 10.1038/Nsmb.2766 |
0.393 |
|
| 2013 |
Clausen AR, Murray MS, Passer AR, Pedersen LC, Kunkel TA. Structure-function analysis of ribonucleotide bypass by B family DNA replicases. Proceedings of the National Academy of Sciences of the United States of America. 110: 16802-7. PMID 24082122 DOI: 10.1073/Pnas.1309119110 |
0.339 |
|
| 2013 |
Xu D, Young JH, Krahn JM, Song D, Corbett KD, Chazin WJ, Pedersen LC, Esko JD. Stable RAGE-heparan sulfate complexes are essential for signal transduction. Acs Chemical Biology. 8: 1611-20. PMID 23679870 DOI: 10.1021/Cb4001553 |
0.344 |
|
| 2013 |
Batra VK, Perera L, Lin P, Shock DD, Beard WA, Pedersen LC, Pedersen LG, Wilson SH. Amino acid substitution in the active site of DNA polymerase β explains the energy barrier of the nucleotidyl transfer reaction. Journal of the American Chemical Society. 135: 8078-88. PMID 23647366 DOI: 10.1021/Ja403842J |
0.585 |
|
| 2013 |
Peterson EJ, Kireev D, Moon AF, Midon M, Janzen WP, Pingoud A, Pedersen LC, Singleton SF. Inhibitors of Streptococcus pneumoniae surface endonuclease EndA discovered by high-throughput screening using a PicoGreen fluorescence assay. Journal of Biomolecular Screening. 18: 247-57. PMID 23015019 DOI: 10.1177/1087057112461153 |
0.309 |
|
| 2012 |
Liu J, Moon AF, Sheng J, Pedersen LC. Understanding the substrate specificity of the heparan sulfate sulfotransferases by an integrated biosynthetic and crystallographic approach. Current Opinion in Structural Biology. 22: 550-7. PMID 22840348 DOI: 10.1016/J.Sbi.2012.07.004 |
0.363 |
|
| 2012 |
Gosavi RA, Moon AF, Kunkel TA, Pedersen LC, Bebenek K. The catalytic cycle for ribonucleotide incorporation by human DNA Pol λ. Nucleic Acids Research. 40: 7518-27. PMID 22584622 DOI: 10.1093/Nar/Gks413 |
0.427 |
|
| 2012 |
Moon AF, Xu Y, Woody SM, Krahn JM, Linhardt RJ, Liu J, Pedersen LC. Dissecting the substrate recognition of 3-O-sulfotransferase for the biosynthesis of anticoagulant heparin. Proceedings of the National Academy of Sciences of the United States of America. 109: 5265-70. PMID 22431632 DOI: 10.1073/Pnas.1117923109 |
0.422 |
|
| 2011 |
Schorzman AN, Perera L, Cutalo-Patterson JM, Pedersen LC, Pedersen LG, Kunkel TA, Tomer KB. Modeling of the DNA-binding site of yeast Pms1 by mass spectrometry. Dna Repair. 10: 454-65. PMID 21354867 DOI: 10.1016/J.Dnarep.2011.01.010 |
0.597 |
|
| 2011 |
Mueller GA, Gosavi RA, Pomés A, Wünschmann S, Moon AF, London RE, Pedersen LC. Ara h 2: crystal structure and IgE binding distinguish two subpopulations of peanut allergic patients by epitope diversity. Allergy. 66: 878-85. PMID 21255036 DOI: 10.1111/J.1398-9995.2010.02532.X |
0.353 |
|
| 2011 |
Bebenek K, Pedersen LC, Kunkel TA. Replication infidelity via a mismatch with Watson-Crick geometry. Proceedings of the National Academy of Sciences of the United States of America. 108: 1862-7. PMID 21233421 DOI: 10.1073/Pnas.1012825108 |
0.396 |
|
| 2011 |
Moon AF, Midon M, Meiss G, Pingoud A, London RE, Pedersen LC. Structural insights into catalytic and substrate binding mechanisms of the strategic EndA nuclease from Streptococcus pneumoniae. Nucleic Acids Research. 39: 2943-53. PMID 21113026 DOI: 10.1093/Nar/Gkq1152 |
0.463 |
|
| 2010 |
Surya Prakash GK, Zibinsky M, Upton TG, Kashemirov BA, McKenna CE, Oertell K, Goodman MF, Batra VK, Pedersen LC, Beard WA, Shock DD, Wilson SH, Olah GA. Synthesis and biological evaluation of fluorinated deoxynucleotide analogs based on bis-(difluoromethylene)triphosphoric acid. Proceedings of the National Academy of Sciences of the United States of America. 107: 15693-8. PMID 20724659 DOI: 10.1073/Pnas.1007430107 |
0.367 |
|
| 2010 |
Mueller GA, Gosavi RA, Krahn JM, Edwards LL, Cuneo MJ, Glesner J, Pomés A, Chapman MD, London RE, Pedersen LC. Der p 5 crystal structure provides insight into the group 5 dust mite allergens. The Journal of Biological Chemistry. 285: 25394-401. PMID 20534590 DOI: 10.1074/Jbc.M110.128306 |
0.388 |
|
| 2010 |
Batra VK, Beard WA, Hou EW, Pedersen LC, Prasad R, Wilson SH. Mutagenic conformation of 8-oxo-7,8-dihydro-2'-dGTP in the confines of a DNA polymerase active site. Nature Structural & Molecular Biology. 17: 889-90. PMID 20526335 DOI: 10.1038/Nsmb.1852 |
0.354 |
|
| 2010 |
Batra VK, Pedersen LC, Beard WA, Wilson SH, Kashemirov BA, Upton TG, Goodman MF, McKenna CE. Halogenated beta,gamma-methylene- and ethylidene-dGTP-DNA ternary complexes with DNA polymerase beta: structural evidence for stereospecific binding of the fluoromethylene analogues. Journal of the American Chemical Society. 132: 7617-25. PMID 20465217 DOI: 10.1021/Ja909370K |
0.375 |
|
| 2010 |
Mueller GA, Edwards LL, Aloor JJ, Fessler MB, Glesner J, Pomés A, Chapman MD, London RE, Pedersen LC. The structure of the dust mite allergen Der p 7 reveals similarities to innate immune proteins. The Journal of Allergy and Clinical Immunology. 125: 909-917.e4. PMID 20226507 DOI: 10.1016/J.Jaci.2009.12.016 |
0.376 |
|
| 2010 |
Moon AF, Mueller GA, Zhong X, Pedersen LC. A synergistic approach to protein crystallization: combination of a fixed-arm carrier with surface entropy reduction. Protein Science : a Publication of the Protein Society. 19: 901-13. PMID 20196072 DOI: 10.1002/Pro.368 |
0.316 |
|
| 2010 |
Arana ME, Holmes SF, Fortune JM, Moon AF, Pedersen LC, Kunkel TA. Functional residues on the surface of the N-terminal domain of yeast Pms1. Dna Repair. 9: 448-57. PMID 20138591 DOI: 10.1016/J.Dnarep.2010.01.010 |
0.432 |
|
| 2010 |
Mueller GA, Edwards L, Aloor JJ, Fessler MB, Pomes A, Chapman MD, London RE, Pedersen LC. The Der p 7 Crystal Structure Reveals Similarities to Innate Immune Proteins The Journal of Allergy and Clinical Immunology. 125. DOI: 10.1016/J.Jaci.2009.12.738 |
0.317 |
|
| 2009 |
Beard WA, Shock DD, Batra VK, Pedersen LC, Wilson SH. DNA polymerase beta substrate specificity: side chain modulation of the "A-rule". The Journal of Biological Chemistry. 284: 31680-9. PMID 19759017 DOI: 10.1074/Jbc.M109.029843 |
0.399 |
|
| 2009 |
Garcia-Diaz M, Bebenek K, Larrea AA, Havener JM, Perera L, Krahn JM, Pedersen LC, Ramsden DA, Kunkel TA. Template strand scrunching during DNA gap repair synthesis by human polymerase lambda. Nature Structural & Molecular Biology. 16: 967-72. PMID 19701199 DOI: 10.1038/Nsmb.1654 |
0.567 |
|
| 2009 |
Cisneros GA, Perera L, Schaaper RM, Pedersen LC, London RE, Pedersen LG, Darden TA. Reaction mechanism of the epsilon subunit of E. coli DNA polymerase III: insights into active site metal coordination and catalytically significant residues. Journal of the American Chemical Society. 131: 1550-6. PMID 19119875 DOI: 10.1021/Ja8082818 |
0.574 |
|
| 2008 |
Bethea HN, Xu D, Liu J, Pedersen LC. Redirecting the substrate specificity of heparan sulfate 2-O-sulfotransferase by structurally guided mutagenesis. Proceedings of the National Academy of Sciences of the United States of America. 105: 18724-9. PMID 19022906 DOI: 10.1073/Pnas.0806975105 |
0.373 |
|
| 2008 |
Ullah H, Scappini EL, Moon AF, Williams LV, Armstrong DL, Pedersen LC. Structure of a signal transduction regulator, RACK1, from Arabidopsis thaliana. Protein Science : a Publication of the Protein Society. 17: 1771-80. PMID 18715992 DOI: 10.1110/Ps.035121.108 |
0.339 |
|
| 2008 |
Mueller GA, Moon AF, Derose EF, Havener JM, Ramsden DA, Pedersen LC, London RE. A comparison of BRCT domains involved in nonhomologous end-joining: introducing the solution structure of the BRCT domain of polymerase lambda. Dna Repair. 7: 1340-51. PMID 18585102 DOI: 10.1016/J.Dnarep.2008.04.018 |
0.449 |
|
| 2008 |
Zhong X, Pedersen LC, Kunkel TA. Characterization of a replicative DNA polymerase mutant with reduced fidelity and increased translesion synthesis capacity. Nucleic Acids Research. 36: 3892-904. PMID 18503083 DOI: 10.1093/Nar/Gkn312 |
0.402 |
|
| 2008 |
Batra VK, Beard WA, Shock DD, Pedersen LC, Wilson SH. Structures of DNA polymerase beta with active-site mismatches suggest a transient abasic site intermediate during misincorporation. Molecular Cell. 30: 315-24. PMID 18471977 DOI: 10.1016/J.Molcel.2008.02.025 |
0.424 |
|
| 2008 |
Lin P, Batra VK, Pedersen LC, Beard WA, Wilson SH, Pedersen LG. Incorrect nucleotide insertion at the active site of a G:A mismatch catalyzed by DNA polymerase beta. Proceedings of the National Academy of Sciences of the United States of America. 105: 5670-4. PMID 18391201 DOI: 10.1073/Pnas.0801257105 |
0.371 |
|
| 2008 |
Bebenek K, Garcia-Diaz M, Foley MC, Pedersen LC, Schlick T, Kunkel TA. Substrate-induced DNA strand misalignment during catalytic cycling by DNA polymerase lambda. Embo Reports. 9: 459-64. PMID 18369368 DOI: 10.1038/Embor.2008.33 |
0.355 |
|
| 2008 |
Xu D, Moon AF, Song D, Pedersen LC, Liu J. Engineering sulfotransferases to modify heparan sulfate. Nature Chemical Biology. 4: 200-2. PMID 18223645 DOI: 10.1038/Nchembio.66 |
0.359 |
|
| 2007 |
McKenna CE, Kashemirov BA, Upton TG, Batra VK, Goodman MF, Pedersen LC, Beard WA, Wilson SH. (R)-beta,gamma-fluoromethylene-dGTP-DNA ternary complex with DNA polymerase beta. Journal of the American Chemical Society. 129: 15412-3. PMID 18031037 DOI: 10.1021/Ja072127V |
0.347 |
|
| 2007 |
Moon AF, Garcia-Diaz M, Batra VK, Beard WA, Bebenek K, Kunkel TA, Wilson SH, Pedersen LC. The X family portrait: structural insights into biological functions of X family polymerases. Dna Repair. 6: 1709-25. PMID 17631059 DOI: 10.1016/J.Dnarep.2007.05.009 |
0.372 |
|
| 2007 |
Garcia-Diaz M, Bebenek K, Krahn JM, Pedersen LC, Kunkel TA. Role of the catalytic metal during polymerization by DNA polymerase lambda. Dna Repair. 6: 1333-40. PMID 17475573 DOI: 10.1016/J.Dnarep.2007.03.005 |
0.392 |
|
| 2007 |
Xu D, Song D, Pedersen LC, Liu J. Mutational study of heparan sulfate 2-O-sulfotransferase and chondroitin sulfate 2-O-sulfotransferase. The Journal of Biological Chemistry. 282: 8356-67. PMID 17227754 DOI: 10.1074/Jbc.M608062200 |
0.4 |
|
| 2007 |
Sucato CA, Upton TG, Kashemirov BA, Batra VK, Martínek V, Xiang Y, Beard WA, Pedersen LC, Wilson SH, McKenna CE, Florián J, Warshel A, Goodman MF. Modifying the beta,gamma leaving-group bridging oxygen alters nucleotide incorporation efficiency, fidelity, and the catalytic mechanism of DNA polymerase beta. Biochemistry. 46: 461-71. PMID 17209556 DOI: 10.1021/Bi061517B |
0.367 |
|
| 2007 |
Moon AF, Garcia-Diaz M, Bebenek K, Davis BJ, Zhong X, Ramsden DA, Kunkel TA, Pedersen LC. Structural insight into the substrate specificity of DNA Polymerase mu. Nature Structural & Molecular Biology. 14: 45-53. PMID 17159995 DOI: 10.1038/Nsmb1180 |
0.414 |
|
| 2007 |
Ghosh M, Meiss G, Pingoud AM, London RE, Pedersen LC. The nuclease a-inhibitor complex is characterized by a novel metal ion bridge. The Journal of Biological Chemistry. 282: 5682-90. PMID 17138564 DOI: 10.1074/Jbc.M605986200 |
0.382 |
|
| 2007 |
Liu J, Pedersen LC. Anticoagulant heparan sulfate: structural specificity and biosynthesis. Applied Microbiology and Biotechnology. 74: 263-72. PMID 17131147 DOI: 10.1007/S00253-006-0722-X |
0.313 |
|
| 2007 |
Moon AF, Garcia-Diaz M, Bebenek K, Davis BJ, Zhong X, Ramsden DA, Kunkel TA, Pedersen LC. Erratum: Corrigendum: Structural insight into the substrate specificity of DNA Polymerase μ Nature Structural & Molecular Biology. 14: 680-680. DOI: 10.1038/Nsmb0707-680B |
0.38 |
|
| 2006 |
Batra VK, Shock DD, Prasad R, Beard WA, Hou EW, Pedersen LC, Sayer JM, Yagi H, Kumar S, Jerina DM, Wilson SH. Structure of DNA polymerase beta with a benzo[c]phenanthrene diol epoxide-adducted template exhibits mutagenic features. Proceedings of the National Academy of Sciences of the United States of America. 103: 17231-6. PMID 17079493 DOI: 10.1073/Pnas.0605069103 |
0.379 |
|
| 2006 |
Kirby TW, Harvey S, DeRose EF, Chalov S, Chikova AK, Perrino FW, Schaaper RM, London RE, Pedersen LC. Structure of the Escherichia coli DNA polymerase III epsilon-HOT proofreading complex. The Journal of Biological Chemistry. 281: 38466-71. PMID 16973612 DOI: 10.1074/Jbc.M606917200 |
0.392 |
|
| 2006 |
Lin P, Pedersen LC, Batra VK, Beard WA, Wilson SH, Pedersen LG. Energy analysis of chemistry for correct insertion by DNA polymerase beta. Proceedings of the National Academy of Sciences of the United States of America. 103: 13294-9. PMID 16938895 DOI: 10.1073/Pnas.0606006103 |
0.388 |
|
| 2006 |
Picher AJ, García-Díaz M, Bebenek K, Pedersen LC, Kunkel TA, Blanco L. Promiscuous mismatch extension by human DNA polymerase lambda. Nucleic Acids Research. 34: 3259-66. PMID 16807316 DOI: 10.1093/Nar/Gkl377 |
0.362 |
|
| 2006 |
Batra VK, Beard WA, Shock DD, Krahn JM, Pedersen LC, Wilson SH. Magnesium-induced assembly of a complete DNA polymerase catalytic complex. Structure (London, England : 1993). 14: 757-66. PMID 16615916 DOI: 10.1016/J.Str.2006.01.011 |
0.415 |
|
| 2006 |
Garcia-Diaz M, Bebenek K, Krahn JM, Pedersen LC, Kunkel TA. Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase. Cell. 124: 331-42. PMID 16439207 DOI: 10.1016/J.Cell.2005.10.039 |
0.385 |
|
| 2006 |
Ping L, Yang W, Pedersen LC, Negishi M, Pedersen LG. Searching for the minimum energy path in the sulfuryl transfer reaction catalyzed by human estrogen sulfotransferase: Role of enzyme dynamics International Journal of Quantum Chemistry. 106: 2981-2998. DOI: 10.1002/Qua.21123 |
0.316 |
|
| 2005 |
Chen J, Avci FY, Muñoz EM, McDowell LM, Chen M, Pedersen LC, Zhang L, Linhardt RJ, Liu J. Enzymatic redesigning of biologically active heparan sulfate. The Journal of Biological Chemistry. 280: 42817-25. PMID 16260789 DOI: 10.1074/Jbc.M504338200 |
0.314 |
|
| 2005 |
Garcia-Diaz M, Bebenek K, Gao G, Pedersen LC, London RE, Kunkel TA. Structure-function studies of DNA polymerase lambda. Dna Repair. 4: 1358-67. PMID 16213194 DOI: 10.1016/J.Dnarep.2005.09.001 |
0.337 |
|
| 2005 |
Prasad R, Batra VK, Yang XP, Krahn JM, Pedersen LC, Beard WA, Wilson SH. Structural insight into the DNA polymerase beta deoxyribose phosphate lyase mechanism. Dna Repair. 4: 1347-57. PMID 16172026 DOI: 10.1016/J.Dnarep.2005.08.009 |
0.418 |
|
| 2005 |
Batra VK, Beard WA, Shock DD, Pedersen LC, Wilson SH. Nucleotide-induced DNA polymerase active site motions accommodating a mutagenic DNA intermediate. Structure (London, England : 1993). 13: 1225-33. PMID 16084394 DOI: 10.1016/J.Str.2005.05.010 |
0.381 |
|
| 2005 |
Ghosh M, Meiss G, Pingoud A, London RE, Pedersen LC. Structural insights into the mechanism of nuclease A, a betabeta alpha metal nuclease from Anabaena. The Journal of Biological Chemistry. 280: 27990-7. PMID 15897201 DOI: 10.1074/Jbc.M501798200 |
0.409 |
|
| 2005 |
Ueda A, Matsui K, Yamamoto Y, Pedersen LC, Sueyoshi T, Negishi M. Thr176 regulates the activity of the mouse nuclear receptor CAR and is conserved in the NR1I subfamily members PXR and VDR. The Biochemical Journal. 388: 623-30. PMID 15610065 DOI: 10.1042/Bj20041572 |
0.331 |
|
| 2005 |
Garcia-Diaz M, Bebenek K, Krahn JM, Kunkel TA, Pedersen LC. A closed conformation for the Pol lambda catalytic cycle. Nature Structural & Molecular Biology. 12: 97-8. PMID 15608652 DOI: 10.1038/Nsmb876 |
0.397 |
|
| 2004 |
Moon AF, Edavettal SC, Krahn JM, Munoz EM, Negishi M, Linhardt RJ, Liu J, Pedersen LC. Structural analysis of the sulfotransferase (3-o-sulfotransferase isoform 3) involved in the biosynthesis of an entry receptor for herpes simplex virus 1. The Journal of Biological Chemistry. 279: 45185-93. PMID 15304505 DOI: 10.1074/Jbc.M405013200 |
0.399 |
|
| 2004 |
Edavettal SC, Carrick K, Shah RR, Pedersen LC, Tropsha A, Pope RM, Liu J. A conformational change in heparan sulfate 3-O-sulfotransferase-1 is induced by binding to heparan sulfate. Biochemistry. 43: 4680-8. PMID 15096036 DOI: 10.1021/Bi0499112 |
0.357 |
|
| 2004 |
Edavettal SC, Lee KA, Negishi M, Linhardt RJ, Liu J, Pedersen LC. Crystal structure and mutational analysis of heparan sulfate 3-O-sulfotransferase isoform 1. The Journal of Biological Chemistry. 279: 25789-97. PMID 15060080 DOI: 10.1074/Jbc.M401089200 |
0.428 |
|
| 2004 |
Garcia-Diaz M, Bebenek K, Krahn JM, Blanco L, Kunkel TA, Pedersen LC. A structural solution for the DNA polymerase lambda-dependent repair of DNA gaps with minimal homology. Molecular Cell. 13: 561-72. PMID 14992725 DOI: 10.1016/S1097-2765(04)00061-9 |
0.383 |
|
| 2003 |
Inoue K, Sobhany M, Transue TR, Oguma K, Pedersen LC, Negishi M. Structural analysis by X-ray crystallography and calorimetry of a haemagglutinin component (HA1) of the progenitor toxin from Clostridium botulinum. Microbiology (Reading, England). 149: 3361-70. PMID 14663070 DOI: 10.1099/Mic.0.26586-0 |
0.416 |
|
| 2003 |
Lee KA, Fuda H, Lee YC, Negishi M, Strott CA, Pedersen LC. Crystal structure of human cholesterol sulfotransferase (SULT2B1b) in the presence of pregnenolone and 3'-phosphoadenosine 5'-phosphate. Rationale for specificity differences between prototypical SULT2A1 and the SULT2BG1 isoforms. The Journal of Biological Chemistry. 278: 44593-9. PMID 12923182 DOI: 10.1074/Jbc.M308312200 |
0.433 |
|
| 2003 |
Shevtsov S, Petrotchenko EV, Pedersen LC, Negishi M. Crystallographic analysis of a hydroxylated polychlorinated biphenyl (OH-PCB) bound to the catalytic estrogen binding site of human estrogen sulfotransferase. Environmental Health Perspectives. 111: 884-8. PMID 12782487 DOI: 10.1289/Ehp.6056 |
0.384 |
|
| 2003 |
Negishi M, Dong J, Darden TA, Pedersen LG, Pedersen LC. Glucosaminylglycan biosynthesis: what we can learn from the X-ray crystal structures of glycosyltransferases GlcAT1 and EXTL2. Biochemical and Biophysical Research Communications. 303: 393-8. PMID 12659829 DOI: 10.1016/S0006-291X(03)00356-5 |
0.391 |
|
| 2003 |
Kakuta Y, Li L, Pedersen LC, Pedersen LG, Negishi M. Heparan sulphate N-sulphotransferase activity: reaction mechanism and substrate recognition. Biochemical Society Transactions. 31: 331-4. PMID 12653630 DOI: 10.1042/Bst0310331 |
0.384 |
|
| 2003 |
Pedersen LC, Dong J, Taniguchi F, Kitagawa H, Krahn JM, Pedersen LG, Sugahara K, Negishi M. Crystal structure of an alpha 1,4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis. The Journal of Biological Chemistry. 278: 14420-8. PMID 12562774 DOI: 10.1074/Jbc.M210532200 |
0.398 |
|
| 2003 |
Mueller SO, Hall JM, Swope DL, Pedersen LC, Korach KS. Molecular determinants of the stereoselectivity of agonist activity of estrogen receptors (ER) alpha and beta. The Journal of Biological Chemistry. 278: 12255-62. PMID 12547836 DOI: 10.1074/Jbc.M203578200 |
0.331 |
|
| 2003 |
Gorokhov A, Negishi M, Johnson EF, Pedersen LC, Perera L, Darden TA, Pedersen LG. Explicit water near the catalytic I helix Thr in the predicted solution structure of CYP2A4. Biophysical Journal. 84: 57-68. PMID 12524265 DOI: 10.1016/S0006-3495(03)74832-2 |
0.598 |
|
| 2002 |
Pedersen LC, Darden TA, Negishi M. Crystal structure of beta 1,3-glucuronyltransferase I in complex with active donor substrate UDP-GlcUA. The Journal of Biological Chemistry. 277: 21869-73. PMID 11950836 DOI: 10.1074/Jbc.M112343200 |
0.409 |
|
| 2002 |
Pedersen LC, Petrotchenko E, Shevtsov S, Negishi M. Crystal structure of the human estrogen sulfotransferase-PAPS complex: evidence for catalytic role of Ser137 in the sulfuryl transfer reaction. The Journal of Biological Chemistry. 277: 17928-32. PMID 11884392 DOI: 10.1074/Jbc.M111651200 |
0.425 |
|
| 2001 |
Negishi M, Pedersen LG, Petrotchenko E, Shevtsov S, Gorokhov A, Kakuta Y, Pedersen LC. Structure and function of sulfotransferases. Archives of Biochemistry and Biophysics. 390: 149-57. PMID 11396917 DOI: 10.1006/Abbi.2001.2368 |
0.409 |
|
| 2001 |
Yoshinari K, Petrotchenko EV, Pedersen LC, Negishi M. Crystal structure-based studies of cytosolic sulfotransferase. Journal of Biochemical and Molecular Toxicology. 15: 67-75. PMID 11284047 DOI: 10.1002/Jbt.1 |
0.415 |
|
| 2001 |
Petrotchenko EV, Pedersen LC, Borchers CH, Tomer KB, Negishi M. The dimerization motif of cytosolic sulfotransferases Febs Letters. 490: 39-43. PMID 11172807 DOI: 10.1016/S0014-5793(01)02129-9 |
0.358 |
|
| 2001 |
Pedersen LC, Darden TA, Kakuta Y, Negishi M. Crystal Structure-Based Analysis of Human Glucuronyltransferase 1 Trends in Glycoscience and Glycotechnology. 13: 121-129. DOI: 10.4052/Tigg.13.121 |
0.327 |
|
| 2000 |
Gorokhov A, Perera L, Darden TA, Negishi M, Pedersen LC, Pedersen LG. Heparan sulfate biosynthesis: a theoretical study of the initial sulfation step by N-deacetylase/N-sulfotransferase. Biophysical Journal. 79: 2909-17. PMID 11106599 DOI: 10.1016/S0006-3495(00)76528-3 |
0.588 |
|
| 2000 |
Pedersen LC, Tsuchida K, Kitagawa H, Sugahara K, Darden TA, Negishi M. Heparan/chondroitin sulfate biosynthesis. Structure and mechanism of human glucuronyltransferase I. The Journal of Biological Chemistry. 275: 34580-5. PMID 10946001 DOI: 10.1074/Jbc.M007399200 |
0.398 |
|
| 2000 |
Pedersen LC, Petrotchenko EV, Negishi M. Crystal structure of SULT2A3, human hydroxysteroid sulfotransferase. Febs Letters. 475: 61-4. PMID 10854859 DOI: 10.1016/S0014-5793(00)01479-4 |
0.446 |
|
| 1999 |
Bidwell LM, McManus ME, Gaedigk A, Kakuta Y, Negishi M, Pedersen L, Martin JL. Crystal structure of human catecholamine sulfotransferase. Journal of Molecular Biology. 293: 521-30. PMID 10543947 DOI: 10.1006/Jmbi.1999.3153 |
0.409 |
|
| 1999 |
Petrotchenko EV, Doerflein ME, Kakuta Y, Pedersen LC, Negishi M. Substrate gating confers steroid specificity to estrogen sulfotransferase. The Journal of Biological Chemistry. 274: 30019-22. PMID 10514486 DOI: 10.1074/Jbc.274.42.30019 |
0.347 |
|
| 1999 |
Ong E, Yeh JC, Ding Y, Hindsgaul O, Pedersen LC, Negishi M, Fukuda M. Structure and function of HNK-1 sulfotransferase. Identification of donor and acceptor binding sites by site-directed mutagenesis. The Journal of Biological Chemistry. 274: 25608-12. PMID 10464296 DOI: 10.1074/Jbc.274.36.25608 |
0.407 |
|
| 1999 |
Kakuta Y, Sueyoshi T, Negishi M, Pedersen LC. Crystal structure of the sulfotransferase domain of human heparan sulfate N-deacetylase/ N-sulfotransferase 1. The Journal of Biological Chemistry. 274: 10673-6. PMID 10196134 DOI: 10.1074/Jbc.274.16.10673 |
0.341 |
|
| 1999 |
Marsolais F, Laviolette M, Kakuta Y, Negishi M, Pedersen LC, Auger M, Varin L. 3'-Phosphoadenosine 5'-phosphosulfate binding site of flavonol 3-sulfotransferase studied by affinity chromatography and 31P NMR. Biochemistry. 38: 4066-71. PMID 10194320 DOI: 10.1021/Bi982239M |
0.391 |
|
| 1999 |
Fox BA, Yee VC, Pedersen LC, Le Trong I, Bishop PD, Stenkamp RE, Teller DC. Identification of the calcium binding site and a novel ytterbium site in blood coagulation factor XIII by x-ray crystallography. The Journal of Biological Chemistry. 274: 4917-23. PMID 9988734 DOI: 10.1074/Jbc.274.8.4917 |
0.635 |
|
| 1999 |
Bartolotti L, Kakuta Y, Pedersen L, Negishi M. A quantum mechanical study of the transfer of biological sulfate Journal of Molecular Structure: Theochem. 461: 105-111. DOI: 10.1016/S0166-1280(98)00424-2 |
0.314 |
|
| 1998 |
Behnke CA, Yee VC, Trong IL, Pedersen LC, Stenkamp RE, Kim SS, Reeck GR, Teller DC. Structural determinants of the bifunctional corn Hageman factor inhibitor: x-ray crystal structure at 1.95 A resolution. Biochemistry. 37: 15277-88. PMID 9799488 DOI: 10.1021/Bi9812266 |
0.756 |
|
| 1998 |
Kakuta Y, Petrotchenko EV, Pedersen LC, Negishi M. The sulfuryl transfer mechanism. Crystal structure of a vanadate complex of estrogen sulfotransferase and mutational analysis. The Journal of Biological Chemistry. 273: 27325-30. PMID 9765259 DOI: 10.1074/Jbc.273.42.27325 |
0.373 |
|
| 1998 |
Sueyoshi T, Kakuta Y, Pedersen LC, Wall FE, Pedersen LG, Negishi M. A role of Lys614 in the sulfotransferase activity of human heparan sulfate N-deacetylase/N-sulfotransferase. Febs Letters. 433: 211-4. PMID 9744796 DOI: 10.1016/S0014-5793(98)00913-2 |
0.344 |
|
| 1998 |
Kakuta Y, Pedersen LG, Pedersen LC, Negishi M. Conserved structural motifs in the sulfotransferase family. Trends in Biochemical Sciences. 23: 129-30. PMID 9584614 DOI: 10.1016/S0968-0004(98)01182-7 |
0.312 |
|
| 1998 |
Kakuta Y, Pedersen LC, Chae K, Song WC, Leblanc D, London R, Carter CW, Negishi M. Mouse steroid sulfotransferases: substrate specificity and preliminary X-ray crystallographic analysis. Biochemical Pharmacology. 55: 313-7. PMID 9484797 DOI: 10.1016/S0006-2952(97)00465-6 |
0.355 |
|
| 1997 |
Kakuta Y, Pedersen LG, Carter CW, Negishi M, Pedersen LC. Crystal structure of estrogen sulphotransferase. Nature Structural Biology. 4: 904-8. PMID 9360604 DOI: 10.1038/Nsb1197-904 |
0.363 |
|
| 1996 |
Yee VC, Le Trong I, Bishop PD, Pedersen LC, Stenkamp RE, Teller DC. Structure and function studies of factor XIIIa by x-ray crystallography. Seminars in Thrombosis and Hemostasis. 22: 377-84. PMID 8989820 DOI: 10.1055/S-2007-999035 |
0.648 |
|
| 1995 |
Yee VC, Pedersen LC, Bishop PD, Stenkamp RE, Teller DC. Structural evidence that the activation peptide is not released upon thrombin cleavage of factor XIII. Thrombosis Research. 78: 389-97. PMID 7660355 DOI: 10.1016/0049-3848(95)00072-Y |
0.617 |
|
| 1995 |
Pedersen LC, Benning MM, Holden HM. Structural investigation of the antibiotic and ATP-binding sites in kanamycin nucleotidyltransferase Biochemistry. 34: 13305-13311. PMID 7577914 DOI: 10.1021/Bi00041A005 |
0.58 |
|
| 1994 |
Pedersen LC, Yee VC, von Dassow G, Hazeghazam M, Reeck GR, Stenkamp RE, Teller DC. The corn inhibitor of blood coagulation factor XIIa. Crystallization and preliminary crystallographic analysis. Journal of Molecular Biology. 236: 385-7. PMID 8107123 DOI: 10.1006/Jmbi.1994.1147 |
0.576 |
|
| 1994 |
Pedersen LC, Yee VC, Bishop PD, Le Trong I, Teller DC, Stenkamp RE. Transglutaminase factor XIII uses proteinase-like catalytic triad to crosslink macromolecules. Protein Science : a Publication of the Protein Society. 3: 1131-5. PMID 7920263 DOI: 10.1002/Pro.5560030720 |
0.644 |
|
| 1994 |
Yee VC, Pedersen LC, Le Trong I, Bishop PD, Stenkamp RE, Teller DC. Three-dimensional structure of a transglutaminase: human blood coagulation factor XIII. Proceedings of the National Academy of Sciences of the United States of America. 91: 7296-300. PMID 7913750 DOI: 10.1073/Pnas.91.15.7296 |
0.645 |
|
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