Ellen T. Roche, Ph.D. - Publications

Affiliations: 
2017- Institute for Medical Engineering and Science Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
Medical Devices, Soft Robotics, Biomaterials
Website:
https://imes.mit.edu/people/faculty/ellen-roche/

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Park C, Singh M, Saeed MY, Nguyen CT, Roche ET. Biorobotic hybrid heart as a benchtop cardiac mitral valve simulator. Device. 2. PMID 38312504 DOI: 10.1016/j.device.2023.100217  0.329
2023 Singh M, Teodorescu DL, Rowlett M, Wang SX, Balcells M, Park C, Bernardo B, McGarel S, Reeves C, Mehra MR, Zhao X, Yuk H, Roche ET. A Tunable Soft Silicone Bioadhesive for Secure Anchoring of Diverse Medical Devices to Wet Biological Tissue. Advanced Materials (Deerfield Beach, Fla.). e2307288. PMID 37865838 DOI: 10.1002/adma.202307288  0.518
2023 Beatty R, Mendez KL, Schreiber LHJ, Tarpey R, Whyte W, Fan Y, Robinson ST, O'Dwyer J, Simpkin AJ, Tannian J, Dockery P, Dolan EB, Roche ET, Duffy GP. Soft robot-mediated autonomous adaptation to fibrotic capsule formation for improved drug delivery. Science Robotics. 8: eabq4821. PMID 37647382 DOI: 10.1126/scirobotics.abq4821  0.3
2023 Rosalia L, Ozturk C, Wang SX, Quevedo-Moreno D, Saeed MY, Mauskapf A, Roche ET. Soft robotics-enabled large animal model of HFpEF hemodynamics for device testing. Biorxiv : the Preprint Server For Biology. PMID 37547009 DOI: 10.1101/2023.07.26.550654  0.351
2023 Mendez K, Whyte W, Freedman BR, Rothenbucher SE, Fan Y, Singh M, Cruz JC, Varela CE, Li J, Mooney DJ, Roche ET. Mechanoresponsive drug release from a flexible, tissue-adherent, hybrid hydrogel actuator. Advanced Materials (Deerfield Beach, Fla.). e2303301. PMID 37310046 DOI: 10.1002/adma.202303301  0.614
2023 Lee Y, Koehler F, Dillon T, Loke G, Kim Y, Marion J, Antonini MJ, Garwood I, Sahasrabudhe A, Nagao K, Zhao X, Fink Y, Roche ET, Anikeeva P. Magnetically Actuated Fiber-Based Soft Robots. Advanced Materials (Deerfield Beach, Fla.). e2301916. PMID 37269476 DOI: 10.1002/adma.202301916  0.455
2023 Rosalia L, Ozturk C, Goswami D, Bonnemain J, Wang SX, Bonner B, Weaver JC, Puri R, Kapadia S, Nguyen CT, Roche ET. Soft robotic patient-specific hydrodynamic model of aortic stenosis and ventricular remodeling. Science Robotics. 8: eade2184. PMID 36812335 DOI: 10.1126/scirobotics.ade2184  0.702
2022 Ozturk C, Schmid Daners M, Zhao X, Roche ET, Nguyen CT. Editorial: Cardiovascular engineering. Frontiers in Cardiovascular Medicine. 9: 1089794. PMID 36479566 DOI: 10.3389/fcvm.2022.1089794  0.364
2022 Rosalia L, Ozturk C, Coll-Font J, Fan Y, Nagata Y, Singh M, Goswami D, Mauskapf A, Chen S, Eder RA, Goffer EM, Kim JH, Yurista S, Bonner BP, Foster AN, ... ... Roche ET, et al. A soft robotic sleeve mimicking the haemodynamics and biomechanics of left ventricular pressure overload and aortic stenosis. Nature Biomedical Engineering. PMID 36163494 DOI: 10.1038/s41551-022-00937-8  0.693
2022 Whyte W, Goswami D, Wang SX, Fan Y, Ward NA, Levey RE, Beatty R, Robinson ST, Sheppard D, O'Connor R, Monahan DS, Trask L, Mendez KL, Varela CE, Horvath MA, ... ... Roche ET, et al. Dynamic actuation enhances transport and extends therapeutic lifespan in an implantable drug delivery platform. Nature Communications. 13: 4496. PMID 35922421 DOI: 10.1038/s41467-022-32147-w  0.7
2021 Yuk H, Wu J, Sarrafian TL, Mao X, Varela CE, Roche ET, Griffiths LG, Nabzdyk CS, Zhao X. Rapid and coagulation-independent haemostatic sealing by a paste inspired by barnacle glue. Nature Biomedical Engineering. PMID 34373600 DOI: 10.1038/s41551-021-00769-y  0.46
2021 Goswami D, Domingo-Lopez DA, Ward NA, Millman JR, Duffy GP, Dolan EB, Roche ET. Design Considerations for Macroencapsulation Devices for Stem Cell Derived Islets for the Treatment of Type 1 Diabetes. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2100820. PMID 34155834 DOI: 10.1002/advs.202100820  0.668
2020 Park C, Fan Y, Hager G, Yuk H, Singh M, Rojas A, Hameed A, Saeed M, Vasilyev NV, Steele TWJ, Zhao X, Nguyen CT, Roche ET. An organosynthetic dynamic heart model with enhanced biomimicry guided by cardiac diffusion tensor imaging. Science Robotics. 5. PMID 33022595 DOI: 10.1126/scirobotics.aay9106  0.519
2020 Deng J, Yuk H, Wu J, Varela CE, Chen X, Roche ET, Guo CF, Zhao X. Electrical bioadhesive interface for bioelectronics. Nature Materials. PMID 32989277 DOI: 10.1038/s41563-020-00814-2  0.488
2020 Roche ET. Minimally Invasive Delivery of Tissue Engineered Heart Valves to the Pulmonary Annulus. Jacc: Basic to Translational Science. 5: 829-830. PMID 32876644 DOI: 10.1016/J.Jacbts.2020.07.001  0.359
2020 Duffy GP, Robinson ST, O'Connor R, Wylie R, Mauerhofer C, Bellavia G, Straino S, Cianfarani F, Mendez K, Beatty R, Levey R, O'Sullivan J, McDonough L, Kelly H, Roche ET, et al. Implantable Therapeutic Reservoir Systems for Diverse Clinical Applications in Large Animal Models. Advanced Healthcare Materials. e2000305. PMID 32339411 DOI: 10.1002/Adhm.202000305  0.405
2020 Roche ET. Shedding light on heart failure Science Translational Medicine. 12. DOI: 10.1126/Scitranslmed.Abe4436  0.303
2020 Roche E. Paving the path to inpatient printing Science Translational Medicine. 12. DOI: 10.1126/Scitranslmed.Abd3082  0.327
2020 Park C, Fan Y, Hager G, Yuk H, Singh M, Rojas A, Hameed A, Saeed M, Vasilyev NV, Steele TWJ, Zhao X, Nguyen CT, Roche ET. An organosynthetic dynamic heart model with enhanced biomimicry guided by cardiac diffusion tensor imaging Science Robotics. 5: eaay9106. DOI: 10.1126/scirobotics.aay9106  0.519
2020 Duffy GP, Robinson ST, O'Connor R, Wylie R, Mauerhofer C, Bellavia G, Straino S, Cianfarani F, Mendez K, Beatty R, Levey R, O'Sullivan J, McDonough L, Kelly H, Roche ET, et al. Therapeutic Resevoirs: Implantable Therapeutic Reservoir Systems for Diverse Clinical Applications in Large Animal Models (Adv. Healthcare Mater. 11/2020) Advanced Healthcare Materials. 9: 2070035. DOI: 10.1002/Adhm.202070035  0.314
2019 Yuk H, Varela CE, Nabzdyk CS, Mao X, Padera RF, Roche ET, Zhao X. Dry double-sided tape for adhesion of wet tissues and devices. Nature. PMID 31666696 DOI: 10.1038/S41586-019-1710-5  0.526
2019 Shirazi RN, Islam S, Weafer FM, Whyte WD, Varela CE, Villanyi A, Ronan W, McHugh P, Roche ET. Multiscale Experimental and Computational Modeling Approaches to Characterize Therapy Delivery to the Heart from an Implantable Epicardial Biomaterial Reservoir. Advanced Healthcare Materials. e1900228. PMID 31322319 DOI: 10.1002/Adhm.201900228  0.39
2019 Varela CE, Fan Y, Roche ET. Optimizing Epicardial Restraint and Reinforcement Following Myocardial Infarction: Moving Towards Localized, Biomimetic, and Multitherapeutic Options. Biomimetics (Basel, Switzerland). 4. PMID 31105193 DOI: 10.3390/Biomimetics4010007  0.362
2019 Fan Y, Ronan W, Teh I, Schneider JE, Varela CE, Whyte W, McHugh P, Leen S, Roche E. A comparison of two quasi-static computational models for assessment of intra-myocardial injection as a therapeutic strategy for heart failure. International Journal For Numerical Methods in Biomedical Engineering. e3213. PMID 31062508 DOI: 10.1002/Cnm.3213  0.401
2019 Weafer FM, Duffy S, Machado I, Gunning G, Mordasini P, Roche E, McHugh PE, Gilvarry M. Characterization of strut indentation during mechanical thrombectomy in acute ischemic stroke clot analogs. Journal of Neurointerventional Surgery. PMID 30661030 DOI: 10.1136/Neurintsurg-2018-014601  0.312
2019 Roche ET. Implanted device enables responsive bladder control. Nature. 565: 298-300. PMID 30643302 DOI: 10.1038/D41586-018-07811-1  0.309
2019 Shirazi RN, Islam S, Weafer FM, Whyte W, Varela CE, Villanyi A, Ronan W, McHugh P, Roche ET. Multiscale Computational Modeling: Multiscale Experimental and Computational Modeling Approaches to Characterize Therapy Delivery to the Heart from an Implantable Epicardial Biomaterial Reservoir (Adv. Healthcare Mater. 16/2019) Advanced Healthcare Materials. 8: 1970068. DOI: 10.1002/Adhm.201970068  0.33
2018 Whyte W, Roche ET, Varela CE, Mendez K, Islam S, O'Neill H, Weafer F, Shirazi RN, Weaver JC, Vasilyev NV, McHugh PE, Murphy B, Duffy GP, Walsh CJ, Mooney DJ. Sustained release of targeted cardiac therapy with a replenishable implanted epicardial reservoir. Nature Biomedical Engineering. 2: 416-428. PMID 31011199 DOI: 10.1038/S41551-018-0247-5  0.638
2018 Horvath MA, Varela CE, Dolan EB, Whyte W, Monahan DS, Payne CJ, Wamala IA, Vasilyev NV, Pigula FA, Mooney DJ, Walsh CJ, Duffy GP, Roche ET. Towards Alternative Approaches for Coupling of a Soft Robotic Sleeve to the Heart. Annals of Biomedical Engineering. PMID 29766347 DOI: 10.1007/S10439-018-2046-2  0.661
2017 Payne CJ, Wamala I, Abah C, Thalhofer T, Saeed M, Bautista-Salinas D, Horvath MA, Vasilyev NV, Roche ET, Pigula FA, Walsh CJ. An Implantable Extracardiac Soft Robotic Device for the Failing Heart: Mechanical Coupling and Synchronization. Soft Robotics. 4: 241-250. PMID 29182083 DOI: 10.1089/soro.2016.0076  0.586
2017 Wamala I, Roche ET, Pigula FA. The use of soft robotics in cardiovascular therapy Expert Review of Cardiovascular Therapy. 15: 767-774. PMID 28817983 DOI: 10.1080/14779072.2017.1366313  0.385
2017 Horvath MA, Wamala I, Rytkin E, Doyle E, Payne CJ, Thalhofer T, Berra I, Solovyeva A, Saeed M, Hendren S, Roche ET, Del Nido PJ, Walsh CJ, Vasilyev NV. An Intracardiac Soft Robotic Device for Augmentation of Blood Ejection from the Failing Right Ventricle. Annals of Biomedical Engineering. PMID 28512702 DOI: 10.1007/S10439-017-1855-Z  0.621
2017 Roche ET, Horvath MA, Wamala I, Alazmani A, Song SE, Whyte W, Machaidze Z, Payne CJ, Weaver JC, Fishbein G, Kuebler J, Vasilyev NV, Mooney DJ, Pigula FA, Walsh CJ. Soft robotic sleeve supports heart function. Science Translational Medicine. 9. PMID 28100834 DOI: 10.1126/Scitranslmed.Aaf3925  0.675
2016 O'Neill HS, Gallagher LB, O'Sullivan J, Whyte W, Curley C, Dolan E, Hameed A, O'Dwyer J, Payne C, O'Reilly D, Ruiz-Hernandez E, Roche ET, O'Brien FJ, Cryan SA, Kelly H, et al. Biomaterial-Enhanced Cell and Drug Delivery: Lessons Learned in the Cardiac Field and Future Perspectives. Advanced Materials (Deerfield Beach, Fla.). PMID 26840955 DOI: 10.1002/Adma.201505349  0.397
2016 Cezar CA, Roche ET, Vandenburgh HH, Duda GN, Walsh CJ, Mooney DJ. Biologic-free mechanically induced muscle regeneration. Proceedings of the National Academy of Sciences of the United States of America. PMID 26811474 DOI: 10.1073/Pnas.1517517113  0.587
2015 Roche ET, Fabozzo A, Lee Y, Polygerinos P, Friehs I, Schuster L, Whyte W, Casar Berazaluce AM, Bueno A, Lang N, Pereira MJ, Feins E, Wasserman S, O'Cearbhaill ED, Vasilyev NV, et al. A light-reflecting balloon catheter for atraumatic tissue defect repair. Science Translational Medicine. 7: 306ra149. PMID 26400910 DOI: 10.1126/Scitranslmed.Aaa2406  0.66
2015 Hastings CL, Roche ET, Ruiz-Hernandez E, Schenke-Layland K, Walsh CJ, Duffy GP. Drug and cell delivery for cardiac regeneration. Advanced Drug Delivery Reviews. 84: 85-106. PMID 25172834 DOI: 10.1016/J.Addr.2014.08.006  0.571
2014 Roche ET, Hastings CL, Lewin SA, Shvartsman DE, Brudno Y, Vasilyev NV, O'Brien FJ, Walsh CJ, Duffy GP, Mooney DJ. Comparison of biomaterial delivery vehicles for improving acute retention of stem cells in the infarcted heart. Biomaterials. 35: 6850-8. PMID 24862441 DOI: 10.1016/J.Biomaterials.2014.04.114  0.731
2014 Roche ET, Wohlfarth R, Overvelde JT, Vasilyev NV, Pigula FA, Mooney DJ, Bertoldi K, Walsh CJ. A bioinspired soft actuated material. Advanced Materials (Deerfield Beach, Fla.). 26: 1200-6. PMID 24227698 DOI: 10.1002/Adma.201304018  0.681
2014 Isakov A, Murdaugh KM, Burke WC, Zimmerman S, Roche E, Holland D, Einarsson JI, Walsh CJ. A New Laparoscopic Morcellator Using an Actuated Wire Mesh and Bag Journal of Medical Devices. 8. DOI: 10.1115/1.4026294  0.575
2014 Roche ET, Wohlfarth R, Overvelde JTB, Vasilyev NV, Pigula FA, Mooney DJ, Bertoldi K, Walsh CJ. Actuators: A Bioinspired Soft Actuated Material (Adv. Mater. 8/2014) Advanced Materials. 26: 1145-1145. DOI: 10.1002/Adma.201470047  0.675
2013 Obiajulu SC, Roche ET, Pigula FA, Walsh CJ. Soft pneumatic artificial muscles with low threshold pressures for a cardiac compression device Proceedings of the Asme Design Engineering Technical Conference. 6. DOI: 10.1115/DETC2013-13004  0.526
2013 Frech AJ, Orozco D, Davoudi K, Ding C, Field R, Yasin R, Roche E, Holland D, Walsh C. Laparoscopic device for direct and indirect suction Journal of Medical Devices, Transactions of the Asme. 7. DOI: 10.1115/1.4024519  0.558
2013 Pardo-Martin C, Duffy M, Hoffman K, Poddar R, Holland D, Roche E, Walsh C, Loughlin K. Minimally invasive device for rapid urethrovesical anastomosis Journal of Medical Devices, Transactions of the Asme. 7. DOI: 10.1115/1.4024503  0.516
2013 Wan Q, Schoppe O, Gunasekaran S, Holland D, Roche E, Hur H, Walsh C. Multifunctional Laparoscopic Trocar With Built-in Fascial Closure and Stabilization Journal of Medical Devices. 7. DOI: 10.1115/1.4024478  0.477
2005 O'flynn PM, Roche ET, Pandit AS. Generating an ex vivo vascular model. Asaio Journal. 51: 426-433. PMID 16156309 DOI: 10.1097/01.Mat.0000170629.92765.Bb  0.306
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