William E. Royer

Affiliations: 
Clark University, Worcester, MA, United States 
Area:
Biochemistry
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"William Royer"
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Nichols JC, Schiffer CA, Royer WE. (2021) NAD(H) phosphates mediate tetramer assembly of human C-terminal binding protein (CtBP). The Journal of Biological Chemistry. 100351
Jecrois AM, Dcona MM, Deng X, et al. (2020) Cryo-EM Structure of CtBP2 Confirms Tetrameric Architecture. Structure (London, England : 1993)
Lockbaum GJ, Leidner F, Royer WE, et al. (2020) Optimizing the refinement of merohedrally twinned P6 HIV-1 protease-inhibitor cocrystal structures. Acta Crystallographica. Section D, Structural Biology. 76: 302-310
Jecrois AM, Bellesis A, Schiffer C, et al. (2020) Cryo‐EM Structure of CtBP2 Confirms Tetrameric Architecture The Faseb Journal. 34: 1-1
Royer WE, Nichols JC, Schiffer CA. (2020) Illuminating the Structural Determinants for Tetrameric Assembly of Oncogenic CtBP to Guide Inhibitor Design Biophysical Journal. 118: 46a
Royer WE, Bellesis AG, Jecrois AM, et al. (2019) Tetrameric Assembly of the Oncogenic C-Terminal Binding Proteins Biophysical Journal. 116: 62a
Bellesis AG, Jecrois AM, Hayes JA, et al. (2018) Assembly of human C-terminal Binding Protein (CtBP) into tetramers. The Journal of Biological Chemistry
Kouno T, Silvas TV, Hilbert BJ, et al. (2017) Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity. Nature Communications. 8: 15024
Dcona MM, Morris BL, Damle PK, et al. (2017) Abstract 3204: Tryptophan 318/324, the target of C-terminal binding protein (CtBP) inhibitors, plays a critical role in CtBP enzymatic activity, oligomerization and transcriptional coregulation Cancer Research. 77: 3204-3204
Korwar S, Morris BL, Parikh HI, et al. (2016) Design, synthesis, and biological evaluation of substrate-competitive inhibitors of C-terminal Binding Protein (CtBP). Bioorganic & Medicinal Chemistry
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