Samarth Hegde

Affiliations: 
Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Cancer Immunology
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"Samarth Hegde"

Parents

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David G. DeNardo grad student 2014-2019 Washington University
Miriam Merad post-doc (Cell Biology Tree)
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Publications

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LaMarche NM, Hegde S, Park MD, et al. (2023) An IL-4 signalling axis in bone marrow drives pro-tumorigenic myelopoiesis. Nature
Magen A, Hamon P, Fiaschi N, et al. (2023) Intratumoral dendritic cell-CD4 T helper cell niches enable CD8 T cell differentiation following PD-1 blockade in hepatocellular carcinoma. Nature Medicine
Park MD, Reyes-Torres I, LeBerichel J, et al. (2023) TREM2 macrophages drive NK cell paucity and dysfunction in lung cancer. Nature Immunology
Hegde S. (2021) Pancreatic Cancer Immuno-oncology in the Era of Precision Medicine. Indian Journal of Surgical Oncology. 12: 118-127
Hegde S, Leader AM, Merad M. (2021) MDSC: Markers, development, states, and unaddressed complexity. Immunity. 54: 875-884
Vabret N, Britton GJ, Gruber C, et al. (2020) Immunology of COVID-19: Current State of the Science. Immunity
Hegde S, Krisnawan VE, Herzog BH, et al. (2020) Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer. Cancer Cell. 37: 289-307.e9
Panni RZ, Herndon JM, Zuo C, et al. (2019) Agonism of CD11b reprograms innate immunity to sensitize pancreatic cancer to immunotherapies. Science Translational Medicine. 11
Jiang H, Liu X, Knolhoff BL, et al. (2019) Development of resistance to FAK inhibition in pancreatic cancer is linked to stromal depletion. Gut
Jiang H, Hegde S, DeNardo DG. (2017) Tumor-associated fibrosis as a regulator of tumor immunity and response to immunotherapy. Cancer Immunology, Immunotherapy : Cii
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