Year |
Citation |
Score |
2022 |
Piantoni C, Paina M, Molla D, Liu S, Bertoli G, Jiang H, Wang Y, Wang Y, Wang Y, DiFrancesco D, Barbuti A, Bucchi A, Baruscotti M. Chinese natural compound decreases pacemaking of rabbit cardiac sinoatrial cells by targeting second messenger regulation of f-channels. Elife. 11. PMID 35315774 DOI: 10.7554/eLife.75119 |
0.369 |
|
2021 |
Saponaro A, Bauer D, Giese MH, Swuec P, Porro A, Gasparri F, Sharifzadeh AS, Chaves-Sanjuan A, Alberio L, Parisi G, Cerutti G, Clarke OB, Hamacher K, Colecraft HM, Mancia F, ... ... DiFrancesco D, et al. Gating movements and ion permeation in HCN4 pacemaker channels. Molecular Cell. PMID 34166608 DOI: 10.1016/j.molcel.2021.05.033 |
0.355 |
|
2019 |
DiFrancesco D. A Brief History of Pacemaking. Frontiers in Physiology. 10: 1599. PMID 32038284 DOI: 10.3389/fphys.2019.01599 |
0.427 |
|
2019 |
DiFrancesco JC, Castellotti B, Milanesi R, Ragona F, Freri E, Canafoglia L, Franceschetti S, Ferrarese C, Magri S, Taroni F, Costa C, Labate A, Gambardella A, Solazzi R, Binda A, ... ... DiFrancesco D, et al. HCN ion channels and accessory proteins in epilepsy: genetic analysis of a large cohort of patients and review of the literature. Epilepsy Research. 153: 49-58. PMID 30986657 DOI: 10.1016/j.eplepsyres.2019.04.004 |
0.418 |
|
2018 |
Marini C, Porro A, Rastetter A, Dalle C, Rivolta I, Bauer D, Oegema R, Nava C, Parrini E, Mei D, Mercer C, Dhamija R, Chambers C, Coubes C, Thévenon J, ... ... DiFrancesco D, et al. HCN1 mutation spectrum: from neonatal epileptic encephalopathy to benign generalized epilepsy and beyond. Brain : a Journal of Neurology. 141: 3160-3178. PMID 30351409 DOI: 10.1093/Brain/Awy263 |
0.36 |
|
2018 |
Saponaro A, Cantini F, Porro A, Bucchi A, DiFrancesco D, Maione V, Donadoni C, Introini B, Mesirca P, Mangoni ME, Thiel G, Banci L, Santoro B, Moroni A. A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. Elife. 7. PMID 29923826 DOI: 10.7554/Elife.35753 |
0.357 |
|
2018 |
Saponaro A, Cantini F, Porro A, Bucchi A, DiFrancesco D, Maione V, Donadoni C, Introini B, Mesirca P, Mangoni ME, Thiel G, Banci L, Santoro B, Moroni A. Author response: A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels Elife. DOI: 10.7554/Elife.35753.022 |
0.399 |
|
2017 |
Baruscotti M, Bucchi A, Milanesi R, Paina M, Barbuti A, Gnecchi-Ruscone T, Bianco E, Vitali-Serdoz L, Cappato R, DiFrancesco D. A gain-of-function mutation in the cardiac pacemaker HCN4 channel increasing cAMP sensitivity is associated with familial Inappropriate Sinus Tachycardia. European Heart Journal. 38: 280-288. PMID 28182231 DOI: 10.1093/eurheartj/ehv582 |
0.418 |
|
2017 |
Paina M, Piantoni C, Carnevali L, Frosio A, Bucchi A, Barbuti A, Sheng L, Yanyan W, Wang Y, DiFrancesco D, Baruscotti M. A Traditional Chinese Medicine Drug (TMYX) Controls Heart Rate by Modulation of the Pacemaker (F) Channels Biophysical Journal. 112: 412a. DOI: 10.1016/j.bpj.2016.11.2565 |
0.359 |
|
2017 |
Piantoni C, Gualdoni A, Bazzini C, Milanesi R, Adelfio M, Bucchi A, Barbuti A, Pecchiari M, Baruscotti M, DiFrancesco D. HCN3 Channel Expression in Human Leukocytes Biophysical Journal. 112: 415a. DOI: 10.1016/j.bpj.2016.11.2224 |
0.369 |
|
2016 |
Biel S, Aquila M, Hertel B, Berthold A, Neumann T, DiFrancesco D, Moroni A, Thiel G, Kauferstein S. Mutation in S6 domain of HCN4 channel in patient with suspected Brugada syndrome modifies channel function. Pflugers Archiv : European Journal of Physiology. PMID 27553229 DOI: 10.1007/S00424-016-1870-1 |
0.468 |
|
2016 |
Baruscotti M, Bianco E, Bucchi A, DiFrancesco D. Current understanding of the pathophysiological mechanisms responsible for inappropriate sinus tachycardia: role of the If "funny" current. Journal of Interventional Cardiac Electrophysiology : An International Journal of Arrhythmias and Pacing. PMID 26781742 DOI: 10.1007/s10840-015-0097-y |
0.334 |
|
2016 |
Meraviglia V, Wen J, Piacentini L, Campostrini G, Wang C, Florio MC, Azzimato V, Fassina L, Langes M, Wong J, Miragoli M, Gaetano C, Pompilio G, Barbuti A, DiFrancesco D, et al. Higher cardiogenic potential of iPSCs derived from cardiac versus skin stromal cells. Frontiers in Bioscience (Landmark Edition). 21: 719-43. PMID 26709802 DOI: 10.2741/4417 |
0.328 |
|
2016 |
Sag C, Ward A, Crocini C, Watkins A, Hayer S, Wang Y, Rex N, Wagner S, De Franceschi L, Vinchi F, Cimino J, Petrillo S, Silengo L, Altruda F, Maier LS, ... ... DiFrancesco D, et al. Late Breaking Science502Hemopexin counteracts systolic dysfunction induced by heme overload503Inhibition of NF-kappa B suppressed inflammation induced by acute shear stress in endothelial cells: Implications for vein graft failure504Optical treatment of cardiac arrhythmias505Tachypacing-induced heart failure: a metabolomic investigation506Characterization of early left ventricle dysfunction in a relevant experimental model for human rheumatoid arthritis507Circadian rhythm in heart rate is due to an intrinsic circadian clock in the sinus node Cardiovascular Research. 111: S90-S91. DOI: 10.1093/Cvr/Cvw142 |
0.314 |
|
2015 |
DiFrancesco D. HCN4, Sinus Bradycardia and Atrial Fibrillation. Arrhythmia & Electrophysiology Review. 4: 9-13. PMID 26835093 DOI: 10.15420/aer.2015.4.1.9 |
0.465 |
|
2015 |
Ravagli E, Bucchi A, Bartolucci C, Paina M, Baruscotti M, DiFrancesco D, Severi S. Cell-specific Dynamic Clamp analysis of the role of funny If current in cardiac pacemaking. Progress in Biophysics and Molecular Biology. PMID 26718599 DOI: 10.1016/j.pbiomolbio.2015.12.004 |
0.405 |
|
2015 |
DiFrancesco JC, DiFrancesco D. Dysfunctional HCN ion channels in neurological diseases. Frontiers in Cellular Neuroscience. 6: 174. PMID 25805968 DOI: 10.3389/fncel.2015.00071 |
0.493 |
|
2015 |
Meraviglia V, Wen J, Piacentini L, Campostrini G, Wang C, Florio M, Azzimato V, Fassina L, Langes M, Wong J, Miragoli M, Gaetano C, Pompilio G, Barbuti A, DiFrancesco D, et al. High cardiac differentiation properties are evident in induced pluripotent stem cells obtained from atrial mesenchymal cells Vascular Pharmacology. 75: 68. DOI: 10.1016/J.Vph.2015.11.069 |
0.303 |
|
2014 |
D'Souza A, Bucchi A, Johnsen AB, Logantha SJ, Monfredi O, Yanni J, Prehar S, Hart G, Cartwright E, Wisloff U, Dobryznski H, DiFrancesco D, Morris GM, Boyett MR. Exercise training reduces resting heart rate via downregulation of the funny channel HCN4. Nature Communications. 5: 3775. PMID 24825544 DOI: 10.1038/ncomms4775 |
0.36 |
|
2014 |
Lolicato M, Bucchi A, Arrigoni C, Zucca S, Nardini M, Schroeder I, Simmons K, Aquila M, DiFrancesco D, Bolognesi M, Schwede F, Kashin D, Fishwick CW, Johnson AP, Thiel G, et al. Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness. Nature Chemical Biology. 10: 457-62. PMID 24776929 DOI: 10.1038/Nchembio.1521 |
0.401 |
|
2014 |
Barbuti A, DiFrancesco D. The 'funny' side of sepsis. The Journal of Physiology. 592: 1171. PMID 24634015 DOI: 10.1113/jphysiol.2014.271171 |
0.446 |
|
2014 |
Ravagli E, Bucchi A, Bartolucci C, Baruscotti M, DiFrancesco D, Severi S. How “Funny” is the Cardiac Pacemaking? a Quantitative Analysis Based on Dynamic Clamp Recordings Biophysical Journal. 106: 722a. DOI: 10.1016/j.bpj.2013.11.3987 |
0.369 |
|
2014 |
Moroni A, Lolicato M, Bucchi A, Arrigoni C, Zucca S, Nardini M, Simmons K, Aquila M, Schwede F, Thiel G, Bolognesi M, DiFrancesco D. Discovery and Characterization of a Distinct Cyclic Nucleotide Binding Pocket in HCN Channels Biophysical Journal. 106: 627a. DOI: 10.1016/J.Bpj.2013.11.3470 |
0.424 |
|
2013 |
Difrancesco D, Nawathe PA, Robinson RB. Multifactorial impact of channel beta-subunit gene mutation on automaticity. Journal of Cardiovascular Electrophysiology. 24: E26-7. PMID 24015862 DOI: 10.1111/Jce.12235 |
0.319 |
|
2013 |
Nawathe PA, Kryukova Y, Oren RV, Milanesi R, Clancy CE, Lu JT, Moss AJ, Difrancesco D, Robinson RB. An LQTS6 MiRP1 mutation suppresses pacemaker current and is associated with sinus bradycardia. Journal of Cardiovascular Electrophysiology. 24: 1021-7. PMID 23631727 DOI: 10.1111/Jce.12163 |
0.437 |
|
2013 |
DiFrancesco D. Funny channel gene mutations associated with arrhythmias. The Journal of Physiology. 591: 4117-24. PMID 23507880 DOI: 10.1113/jphysiol.2013.253765 |
0.475 |
|
2013 |
Bucchi A, Baruscotti M, Nardini M, Barbuti A, Micheloni S, Bolognesi M, DiFrancesco D. Identification of the molecular site of ivabradine binding to HCN4 channels. Plos One. 8: e53132. PMID 23308150 DOI: 10.1371/journal.pone.0053132 |
0.454 |
|
2012 |
Vecellio M, Meraviglia V, Nanni S, Barbuti A, Scavone A, DiFrancesco D, Farsetti A, Pompilio G, Colombo GI, Capogrossi MC, Gaetano C, Rossini A. In vitro epigenetic reprogramming of human cardiac mesenchymal stromal cells into functionally competent cardiovascular precursors. Plos One. 7: e51694. PMID 23284745 DOI: 10.1371/journal.pone.0051694 |
0.36 |
|
2012 |
Bucchi A, Barbuti A, Difrancesco D, Baruscotti M. Funny Current and Cardiac Rhythm: Insights from HCN Knockout and Transgenic Mouse Models. Frontiers in Physiology. 3: 240. PMID 22783204 DOI: 10.3389/fphys.2012.00240 |
0.458 |
|
2012 |
Severi S, Fantini M, Charawi LA, DiFrancesco D. An updated computational model of rabbit sinoatrial action potential to investigate the mechanisms of heart rate modulation. The Journal of Physiology. 590: 4483-99. PMID 22711956 DOI: 10.1113/jphysiol.2012.229435 |
0.43 |
|
2012 |
Barbuti A, Scavone A, Mazzocchi N, Terragni B, Baruscotti M, Difrancesco D. A caveolin-binding domain in the HCN4 channels mediates functional interaction with caveolin proteins. Journal of Molecular and Cellular Cardiology. 53: 187-95. PMID 22659290 DOI: 10.1016/j.yjmcc.2012.05.013 |
0.466 |
|
2012 |
DiFrancesco D, Noble D. Rebuttal: "The funny current in the context of the coupled clock pacemaker cell system". Heart Rhythm : the Official Journal of the Heart Rhythm Society. 9: 457-8. PMID 21925135 DOI: 10.1016/j.hrthm.2011.09.023 |
0.381 |
|
2012 |
DiFrancesco D, Noble D. The funny current has a major pacemaking role in the sinus node. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 9: 299-301. PMID 21925134 DOI: 10.1016/j.hrthm.2011.09.021 |
0.474 |
|
2012 |
Severi S, Fantini M, Ravagli E, Charawi L, DiFrancesco D. A Validated Computational Model of Cardiac Pacemaking: Mechanisms of Physiological and Pharmacological Rate Modulation Biophysical Journal. 102: 672a. DOI: 10.1016/j.bpj.2011.11.3660 |
0.399 |
|
2011 |
DiFrancesco JC, Barbuti A, Milanesi R, Coco S, Bucchi A, Bottelli G, Ferrarese C, Franceschetti S, Terragni B, Baruscotti M, DiFrancesco D. Recessive loss-of-function mutation in the pacemaker HCN2 channel causing increased neuronal excitability in a patient with idiopathic generalized epilepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 17327-37. PMID 22131395 DOI: 10.1523/JNEUROSCI.3727-11.2011 |
0.421 |
|
2011 |
Avitabile D, Crespi A, Brioschi C, Parente V, Toietta G, Devanna P, Baruscotti M, Truffa S, Scavone A, Rusconi F, Biondi A, D'Alessandra Y, Vigna E, Difrancesco D, Pesce M, et al. Human cord blood CD34+ progenitor cells acquire functional cardiac properties through a cell fusion process. American Journal of Physiology. Heart and Circulatory Physiology. 300: H1875-84. PMID 21357510 DOI: 10.1152/ajpheart.00523.2010 |
0.336 |
|
2011 |
Baruscotti M, Bucchi A, Viscomi C, Mandelli G, Consalez G, Gnecchi-Rusconi T, Montano N, Casali KR, Micheloni S, Barbuti A, DiFrancesco D. Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4. Proceedings of the National Academy of Sciences of the United States of America. 108: 1705-10. PMID 21220308 DOI: 10.1073/pnas.1010122108 |
0.489 |
|
2011 |
Rossini A, Frati C, Lagrasta C, Graiani G, Scopece A, Cavalli S, Musso E, Baccarin M, Di Segni M, Fagnoni F, Germani A, Quaini E, Mayr M, Xu Q, Barbuti A, ... DiFrancesco D, et al. Human cardiac and bone marrow stromal cells exhibit distinctive properties related to their origin. Cardiovascular Research. 89: 650-60. PMID 20833652 DOI: 10.1093/cvr/cvq290 |
0.331 |
|
2010 |
Baruscotti M, Bottelli G, Milanesi R, DiFrancesco JC, DiFrancesco D. HCN-related channelopathies. PflüGers Archiv : European Journal of Physiology. 460: 405-15. PMID 20213494 DOI: 10.1007/s00424-010-0810-8 |
0.495 |
|
2010 |
DiFrancesco D. The role of the funny current in pacemaker activity. Circulation Research. 106: 434-46. PMID 20167941 DOI: 10.1161/CIRCRESAHA.109.208041 |
0.506 |
|
2010 |
DiFrancesco D. Funny channel-based pacemaking. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 7: 276-9. PMID 20022815 DOI: 10.1016/j.hrthm.2009.10.030 |
0.41 |
|
2010 |
Barbuti A, Galvez BG, Crespi A, Scavone A, Baruscotti M, Brioschi C, Cossu G, DiFrancesco D. Mesoangioblasts from ventricular vessels can differentiate in vitro into cardiac myocytes with sinoatrial-like properties. Journal of Molecular and Cellular Cardiology. 48: 415-23. PMID 19837079 DOI: 10.1016/j.yjmcc.2009.10.006 |
0.449 |
|
2010 |
DiFrancesco D. Considerations on the size of currents required for pacemaking Journal of Molecular and Cellular Cardiology. 48: 802-803. DOI: 10.1016/j.yjmcc.2009.11.022 |
0.305 |
|
2009 |
Brioschi C, Micheloni S, Tellez JO, Pisoni G, Longhi R, Moroni P, Billeter R, Barbuti A, Dobrzynski H, Boyett MR, DiFrancesco D, Baruscotti M. Distribution of the pacemaker HCN4 channel mRNA and protein in the rabbit sinoatrial node. Journal of Molecular and Cellular Cardiology. 47: 221-7. PMID 19394343 DOI: 10.1016/j.yjmcc.2009.04.009 |
0.444 |
|
2009 |
Lakatta EG, DiFrancesco D. What keeps us ticking: a funny current, a calcium clock, or both? Journal of Molecular and Cellular Cardiology. 47: 157-70. PMID 19361514 DOI: 10.1016/j.yjmcc.2009.03.022 |
0.485 |
|
2009 |
Chandler NJ, Greener ID, Tellez JO, Inada S, Musa H, Molenaar P, Difrancesco D, Baruscotti M, Longhi R, Anderson RH, Billeter R, Sharma V, Sigg DC, Boyett MR, Dobrzynski H. Molecular architecture of the human sinus node: insights into the function of the cardiac pacemaker. Circulation. 119: 1562-75. PMID 19289639 DOI: 10.1161/Circulationaha.108.804369 |
0.369 |
|
2009 |
Barbuti A, Crespi A, Capilupo D, Mazzocchi N, Baruscotti M, DiFrancesco D. Molecular composition and functional properties of f-channels in murine embryonic stem cell-derived pacemaker cells. Journal of Molecular and Cellular Cardiology. 46: 343-51. PMID 19135060 DOI: 10.1016/j.yjmcc.2008.12.001 |
0.448 |
|
2008 |
Galvez BG, Sampaolesi M, Barbuti A, Crespi A, Covarello D, Brunelli S, Dellavalle A, Crippa S, Balconi G, Cuccovillo I, Molla F, Staszewsky L, Latini R, Difrancesco D, Cossu G. Cardiac mesoangioblasts are committed, self-renewable progenitors, associated with small vessels of juvenile mouse ventricle. Cell Death and Differentiation. 15: 1417-28. PMID 18497758 DOI: 10.1038/cdd.2008.75 |
0.356 |
|
2008 |
Barbuti A, DiFrancesco D. Control of cardiac rate by "funny" channels in health and disease. Annals of the New York Academy of Sciences. 1123: 213-23. PMID 18375593 DOI: 10.1196/annals.1420.024 |
0.509 |
|
2007 |
DiFrancesco D, Borer JS. The funny current: cellular basis for the control of heart rate. Drugs. 67: 15-24. PMID 17999560 DOI: 10.2165/00003495-200767002-00003 |
0.488 |
|
2007 |
Bucchi A, Baruscotti M, Robinson RB, DiFrancesco D. Modulation of rate by autonomic agonists in SAN cells involves changes in diastolic depolarization and the pacemaker current. Journal of Molecular and Cellular Cardiology. 43: 39-48. PMID 17543331 DOI: 10.1016/J.Yjmcc.2007.04.017 |
0.439 |
|
2007 |
Barbuti A, Baruscotti M, DiFrancesco D. The pacemaker current: from basics to the clinics. Journal of Cardiovascular Electrophysiology. 18: 342-7. PMID 17284289 DOI: 10.1111/j.1540-8167.2006.00736.x |
0.395 |
|
2007 |
Bucchi A, Barbuti A, Baruscotti M, DiFrancesco D. Heart rate reduction via selective 'funny' channel blockers. Current Opinion in Pharmacology. 7: 208-13. PMID 17267284 DOI: 10.1016/j.coph.2006.09.005 |
0.46 |
|
2007 |
Barbuti A, Terragni B, Brioschi C, DiFrancesco D. Localization of f-channels to caveolae mediates specific beta2-adrenergic receptor modulation of rate in sinoatrial myocytes. Journal of Molecular and Cellular Cardiology. 42: 71-8. PMID 17070839 DOI: 10.1016/j.yjmcc.2006.09.018 |
0.35 |
|
2007 |
Baruscotti M, Bucchi A, Robinson RB, DiFrancesco D. Autonomic rate modulation in san cells involves changes in diastolic depolarization and the i(f) current Journal of Molecular and Cellular Cardiology. 42: S14. DOI: 10.1016/J.Yjmcc.2007.03.040 |
0.392 |
|
2006 |
DiFrancesco D. Funny channels in the control of cardiac rhythm and mode of action of selective blockers. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 53: 399-406. PMID 16638640 DOI: 10.1016/j.phrs.2006.03.006 |
0.536 |
|
2006 |
Bucchi A, Tognati A, Milanesi R, Baruscotti M, DiFrancesco D. Properties of ivabradine-induced block of HCN1 and HCN4 pacemaker channels. The Journal of Physiology. 572: 335-46. PMID 16484306 DOI: 10.1113/jphysiol.2005.100776 |
0.496 |
|
2006 |
Milanesi R, Baruscotti M, Gnecchi-Ruscone T, DiFrancesco D. Familial sinus bradycardia associated with a mutation in the cardiac pacemaker channel. The New England Journal of Medicine. 354: 151-7. PMID 16407510 DOI: 10.1056/NEJMoa052475 |
0.483 |
|
2006 |
DiFrancesco D. Serious workings of the funny current. Progress in Biophysics and Molecular Biology. 90: 13-25. PMID 15975637 DOI: 10.1016/j.pbiomolbio.2005.05.001 |
0.515 |
|
2005 |
DiFrancesco D. Letter regarding article by Michels et al, "Single-channel properties support a potential contribution of hyperpolarization-activated cyclic nucleotide-gated channels and If to cardiac arrhythmias". Circulation. 112: e72; author reply e7. PMID 16061749 DOI: 10.1161/CIRCULATIONAHA.105.541367 |
0.496 |
|
2005 |
DiFrancesco D. Cardiac pacemaker I(f) current and its inhibition by heart rate-reducing agents. Current Medical Research and Opinion. 21: 1115-22. PMID 16004681 DOI: 10.1185/030079905X50543 |
0.504 |
|
2005 |
Baruscotti M, Bucchi A, Difrancesco D. Physiology and pharmacology of the cardiac pacemaker ("funny") current. Pharmacology & Therapeutics. 107: 59-79. PMID 15963351 DOI: 10.1016/j.pharmthera.2005.01.005 |
0.522 |
|
2004 |
DiFrancesco D, Camm JA. Heart rate lowering by specific and selective I(f) current inhibition with ivabradine: a new therapeutic perspective in cardiovascular disease. Drugs. 64: 1757-65. PMID 15301560 DOI: 10.2165/00003495-200464160-00003 |
0.415 |
|
2004 |
Gravante B, Barbuti A, Milanesi R, Zappi I, Viscomi C, DiFrancesco D. Interaction of the pacemaker channel HCN1 with filamin A. The Journal of Biological Chemistry. 279: 43847-53. PMID 15292205 DOI: 10.1074/jbc.M401598200 |
0.437 |
|
2004 |
Baruscotti M, Difrancesco D. Pacemaker channels. Annals of the New York Academy of Sciences. 1015: 111-21. PMID 15201153 DOI: 10.1196/annals.1302.009 |
0.401 |
|
2004 |
Gazzarrini S, Kang M, Van Etten JL, Tayefeh S, Kast SM, DiFrancesco D, Thiel G, Moroni A. Long distance interactions within the potassium channel pore are revealed by molecular diversity of viral proteins. The Journal of Biological Chemistry. 279: 28443-9. PMID 15105432 DOI: 10.1074/Jbc.M401184200 |
0.375 |
|
2004 |
Barbuti A, Gravante B, Riolfo M, Milanesi R, Terragni B, DiFrancesco D. Localization of pacemaker channels in lipid rafts regulates channel kinetics. Circulation Research. 94: 1325-31. PMID 15073040 DOI: 10.1161/01.RES.0000127621.54132.AE |
0.422 |
|
2004 |
Kang M, Moroni A, Gazzarrini S, DiFrancesco D, Thiel G, Severino M, Van Etten JL. Small potassium ion channel proteins encoded by chlorella viruses. Proceedings of the National Academy of Sciences of the United States of America. 101: 5318-24. PMID 14762169 DOI: 10.1073/Pnas.0307824100 |
0.393 |
|
2003 |
Robinson RB, Baruscotti M, DiFrancesco D. Autonomic modulation of heart rate: pitfalls of nonselective channel blockade. American Journal of Physiology. Heart and Circulatory Physiology. 285: H2865; author reply . PMID 14613917 DOI: 10.1152/ajpheart.00545.2003 |
0.382 |
|
2003 |
Gazzarrini S, Severino M, Lombardi M, Morandi M, DiFrancesco D, Van Etten JL, Thiel G, Moroni A. The viral potassium channel Kcv: structural and functional features. Febs Letters. 552: 12-6. PMID 12972145 DOI: 10.1016/S0014-5793(03)00777-4 |
0.408 |
|
2003 |
Bucchi A, Baruscotti M, Robinson RB, DiFrancesco D. I(f)-dependent modulation of pacemaker rate mediated by cAMP in the presence of ryanodine in rabbit sino-atrial node cells. Journal of Molecular and Cellular Cardiology. 35: 905-13. PMID 12878477 DOI: 10.1016/S0022-2828(03)00150-0 |
0.422 |
|
2003 |
Altomare C, Terragni B, Brioschi C, Milanesi R, Pagliuca C, Viscomi C, Moroni A, Baruscotti M, DiFrancesco D. Heteromeric HCN1-HCN4 channels: a comparison with native pacemaker channels from the rabbit sinoatrial node. The Journal of Physiology. 549: 347-59. PMID 12702747 DOI: 10.1113/jphysiol.2002.027698 |
0.502 |
|
2003 |
DiFrancesco D. If inhibition: A novel mechanism of action European Heart Journal, Supplement. 5: G19-G25. DOI: 10.1016/S1520-765X(03)90004-6 |
0.429 |
|
2002 |
Moroni A, Viscomi C, Sangiorgio V, Pagliuca C, Meckel T, Horvath F, Gazzarrini S, Valbuzzi P, Van Etten JL, DiFrancesco D, Thiel G. The short N-terminus is required for functional expression of the virus-encoded miniature K(+) channel Kcv. Febs Letters. 530: 65-9. PMID 12387867 DOI: 10.1016/S0014-5793(02)03397-5 |
0.385 |
|
2002 |
Qu J, Altomare C, Bucchi A, DiFrancesco D, Robinson RB. Functional comparison of HCN isoforms expressed in ventricular and HEK 293 cells. PflüGers Archiv : European Journal of Physiology. 444: 597-601. PMID 12194012 DOI: 10.1007/S00424-002-0860-7 |
0.501 |
|
2002 |
Demontis GC, Moroni A, Gravante B, Altomare C, Longoni B, Cervetto L, DiFrancesco D. Functional characterisation and subcellular localisation of HCN1 channels in rabbit retinal rod photoreceptors. The Journal of Physiology. 542: 89-97. PMID 12096053 DOI: 10.1113/jphysiol.2002.017640 |
0.483 |
|
2002 |
Bucchi A, Baruscotti M, DiFrancesco D. Current-dependent block of rabbit sino-atrial node I(f) channels by ivabradine. The Journal of General Physiology. 120: 1-13. PMID 12084770 DOI: 10.1085/jgp.20028593 |
0.528 |
|
2002 |
Gazzarrini S, Etten JL, DiFrancesco D, Thiel G, Moroni A. Voltage-dependence of virus-encoded miniature K+ channel Kcv. The Journal of Membrane Biology. 187: 15-25. PMID 12029374 DOI: 10.1007/S00232-001-0147-5 |
0.503 |
|
2002 |
DiFrancesco D, Robinson RB. beta-modulation of pacemaker rate: novel mechanism or novel mechanics of an old one? Circulation Research. 90: E69-9. PMID 11934845 DOI: 10.1161/01.Res.0000014803.05780.E7 |
0.314 |
|
2002 |
Accili EA, Proenza C, Baruscotti M, DiFrancesco D. From funny current to HCN channels: 20 years of excitation. News in Physiological Sciences : An International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society. 17: 32-7. PMID 11821534 DOI: 10.1152/Physiologyonline.2002.17.1.32 |
0.508 |
|
2001 |
Protas L, DiFrancesco D, Robinson RB. L-type but not T-type calcium current changes during postnatal development in rabbit sinoatrial node. American Journal of Physiology. Heart and Circulatory Physiology. 281: H1252-9. PMID 11514294 DOI: 10.1152/Ajpheart.2001.281.3.H1252 |
0.38 |
|
2001 |
Baruscotti M, DiFrancesco D, Robinson RB. Single-channel properties of the sinoatrial node Na+ current in the newborn rabbit. PflüGers Archiv : European Journal of Physiology. 442: 192-6. PMID 11417213 DOI: 10.1007/S004240100527 |
0.523 |
|
2001 |
Viscomi C, Altomare C, Bucchi A, Camatini E, Baruscotti M, Moroni A, DiFrancesco D. C terminus-mediated control of voltage and cAMP gating of hyperpolarization-activated cyclic nucleotide-gated channels. The Journal of Biological Chemistry. 276: 29930-4. PMID 11397812 DOI: 10.1074/jbc.M103971200 |
0.419 |
|
2001 |
Altomare C, Bucchi A, Camatini E, Baruscotti M, Viscomi C, Moroni A, DiFrancesco D. Integrated allosteric model of voltage gating of HCN channels. The Journal of General Physiology. 117: 519-32. PMID 11382803 DOI: 10.1085/jgp.117.6.519 |
0.482 |
|
2001 |
Moroni A, Gorza L, Beltrame M, Gravante B, Vaccari T, Bianchi ME, Altomare C, Longhi R, Heurteaux C, Vitadello M, Malgaroli A, DiFrancesco D. Hyperpolarization-activated cyclic nucleotide-gated channel 1 is a molecular determinant of the cardiac pacemaker current I(f). The Journal of Biological Chemistry. 276: 29233-41. PMID 11328811 DOI: 10.1074/Jbc.M100830200 |
0.53 |
|
2001 |
DiFrancesco D, Moroni A, Baruscotti M, Accili EA. CHAPTER 18 – Cardiac Pacemaker Currents Journal of Biological Chemistry. 276: 357-372. DOI: 10.1016/B978-012656975-9/50020-1 |
0.461 |
|
2000 |
Baruscotti M, DiFrancesco D, Robinson RB. Na(+) current contribution to the diastolic depolarization in newborn rabbit SA node cells. American Journal of Physiology. Heart and Circulatory Physiology. 279: H2303-9. PMID 11045966 DOI: 10.1152/Ajpheart.2000.279.5.H2303 |
0.455 |
|
2000 |
Altomare C, Barbuti A, Viscomi C, Baruscotti M, DiFrancesco D. Effects of dronedarone on acetylcholine-activated current in rabbit SAN cells. British Journal of Pharmacology. 130: 1315-20. PMID 10903971 DOI: 10.1038/sj.bjp.0703446 |
0.465 |
|
2000 |
Moroni A, Barbuti A, Altomare C, Viscomi C, Morgan J, Baruscotti M, DiFrancesco D. Kinetic and ionic properties of the human HCN2 pacemaker channel. PflüGers Archiv : European Journal of Physiology. 439: 618-26. PMID 10764222 DOI: 10.1007/s004240050985 |
0.535 |
|
2000 |
Moroni A, Gazzarrini S, Cerana R, Colombo R, Sutter JU, DiFrancesco D, Gradmann D, Thiel G. Mutation in pore domain uncovers cation- and voltage-sensitive recovery from inactivation in KAT1 channel. Biophysical Journal. 78: 1862-71. PMID 10733966 DOI: 10.1016/S0006-3495(00)76735-X |
0.462 |
|
2000 |
Plugge B, Gazzarrini S, Nelson M, Cerana R, Van Etten JL, Derst C, DiFrancesco D, Moroni A, Thiel G. A potassium channel protein encoded by chlorella virus PBCV-1. Science (New York, N.Y.). 287: 1641-4. PMID 10698737 DOI: 10.1126/Science.287.5458.1641 |
0.382 |
|
1999 |
Barbuti A, Baruscotti M, Altomare C, Moroni A, DiFrancesco D. Action of internal pronase on the f-channel kinetics in the rabbit SA node. The Journal of Physiology. 520: 737-44. PMID 10545140 DOI: 10.1111/j.1469-7793.1999.00737.x |
0.519 |
|
1999 |
Vaccari T, Moroni A, Rocchi M, Gorza L, Bianchi ME, Beltrame M, DiFrancesco D. The human gene coding for HCN2, a pacemaker channel of the heart. Biochimica Et Biophysica Acta. 1446: 419-25. PMID 10524219 DOI: 10.1016/S0167-4781(99)00092-5 |
0.464 |
|
1999 |
Gasparini S, DiFrancesco D. Action of serotonin on the hyperpolarization-activated cation current (Ih) in rat CA1 hippocampal neurons. The European Journal of Neuroscience. 11: 3093-100. PMID 10510173 DOI: 10.1046/j.1460-9568.1999.00728.x |
0.57 |
|
1999 |
DiFrancesco D. Dual allosteric modulation of pacemaker (f) channels by cAMP and voltage in rabbit SA node. The Journal of Physiology. 515: 367-76. PMID 10050004 DOI: 10.1111/J.1469-7793.1999.367Ac.X |
0.518 |
|
1998 |
Accili EA, Redaelli G, DiFrancesco D. Two distinct pathways of muscarinic current responses in rabbit sino-atrial node myocytes. PflüGers Archiv : European Journal of Physiology. 437: 164-7. PMID 9817803 DOI: 10.1007/s004240050763 |
0.433 |
|
1997 |
Gasparini S, DiFrancesco D. Action of the hyperpolarization-activated current (Ih) blocker ZD 7288 in hippocampal CA1 neurons. PflüGers Archiv : European Journal of Physiology. 435: 99-106. PMID 9359908 DOI: 10.1007/s004240050488 |
0.601 |
|
1997 |
Bois P, Renaudon B, Baruscotti M, Lenfant J, DiFrancesco D. Activation of f-channels by cAMP analogues in macropatches from rabbit sino-atrial node myocytes. The Journal of Physiology. 501: 565-71. PMID 9218217 DOI: 10.1111/j.1469-7793.1997.565bm.x |
0.46 |
|
1997 |
Accili EA, Redaelli G, DiFrancesco D. Differential control of the hyperpolarization-activated current (i(f)) by cAMP gating and phosphatase inhibition in rabbit sino-atrial node myocytes. The Journal of Physiology. 500: 643-51. PMID 9161982 DOI: 10.1113/Jphysiol.1997.Sp022049 |
0.432 |
|
1997 |
Janigro D, Gasparini S, D'Ambrosio R, McKhann G, DiFrancesco D. Reduction of K+ uptake in glia prevents long-term depression maintenance and causes epileptiform activity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 2813-24. PMID 9092603 DOI: 10.1523/Jneurosci.17-08-02813.1997 |
0.604 |
|
1997 |
Accili EA, Robinson RB, DiFrancesco D. Properties and modulation of If in newborn versus adult cardiac SA node. The American Journal of Physiology. 272: H1549-52. PMID 9087633 DOI: 10.1152/Ajpheart.1997.272.3.H1549 |
0.412 |
|
1997 |
Baruscotti M, Westenbroek R, Catterall WA, DiFrancesco D, Robinson RB. The newborn rabbit sino-atrial node expresses a neuronal type I-like Na+ channel. The Journal of Physiology. 498: 641-8. PMID 9051576 DOI: 10.1113/Jphysiol.1997.Sp021889 |
0.431 |
|
1996 |
Zaza A, Robinson RB, DiFrancesco D. Basal responses of the L-type Ca2+ and hyperpolarization-activated currents to autonomic agonists in the rabbit sino-atrial node. The Journal of Physiology. 491: 347-55. PMID 8866859 DOI: 10.1113/Jphysiol.1996.Sp021220 |
0.374 |
|
1996 |
Zaza A, Rocchetti M, DiFrancesco D. Modulation of the hyperpolarization-activated current (I(f)) by adenosine in rabbit sinoatrial myocytes. Circulation. 94: 734-41. PMID 8772696 DOI: 10.1161/01.Cir.94.4.734 |
0.342 |
|
1996 |
Baruscotti M, DiFrancesco D, Robinson RB. A TTX-sensitive inward sodium current contributes to spontaneous activity in newborn rabbit sino-atrial node cells. The Journal of Physiology. 492: 21-30. PMID 8730579 DOI: 10.1113/Jphysiol.1996.Sp021285 |
0.437 |
|
1996 |
Mazzanti M, Assandri R, Ferroni A, DiFrancesco D. Cytoskeletal control of rectification and expression of four substates in cardiac inward rectifier K+ channels. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 10: 357-61. PMID 8641571 DOI: 10.1096/Fasebj.10.2.8641571 |
0.478 |
|
1996 |
Accili EA, Redaelli G, DiFrancesco D. Activation of the hyperpolarization-activated current (if) in sino-atrial node myocytes of the rabbit by vasoactive intestinal peptide. PflüGers Archiv : European Journal of Physiology. 431: 803-5. PMID 8596736 DOI: 10.1007/BF02253849 |
0.43 |
|
1996 |
Accili EA, DiFrancesco D. Inhibition of the hyperpolarization-activated current (if) of rabbit SA node myocytes by niflumic acid. PflüGers Archiv : European Journal of Physiology. 431: 757-62. PMID 8596727 DOI: 10.1007/BF02253840 |
0.476 |
|
1996 |
Accili E, Redaelli G, DiFrancesco D. Activation of the hyperpolarization-activated current (i PflüGers Archiv European Journal of Physiology. 431: 803. DOI: 10.1007/s004240050071 |
0.375 |
|
1995 |
DiFrancesco D. Cardiac pacemaker: 15 years of "new" interpretation. Acta Cardiologica. 50: 413-27. PMID 8932564 |
0.326 |
|
1995 |
DiFrancesco D. Cesium and the pacemaker current. Journal of Cardiovascular Electrophysiology. 6: 1152-5. PMID 8720217 DOI: 10.1111/J.1540-8167.1995.Tb00394.X |
0.384 |
|
1995 |
DiFrancesco D. The pacemaker current (I(f)) plays an important role in regulating SA node pacemaker activity. Cardiovascular Research. 30: 307-8. PMID 7585819 DOI: 10.1016/S0008-6363(95)00029-1 |
0.368 |
|
1995 |
DiFrancesco D. The onset and autonomic regulation of cardiac pacemaker activity: relevance of the f current. Cardiovascular Research. 29: 449-56. PMID 7540954 DOI: 10.1016/0008-6363(96)88518-X |
0.419 |
|
1995 |
Moroni A, Bardella L, Difrancesco D. Expression of kat1, a plant inward-rectifying potassium channel, in xenopus oocytes Giornale Botanico Italiano. 129: 1068-1069. DOI: 10.1080/11263509509440940 |
0.375 |
|
1994 |
DiFrancesco D. Some properties of the UL-FS 49 block of the hyperpolarization-activated current (i(f)) in sino-atrial node myocytes. PflüGers Archiv : European Journal of Physiology. 427: 64-70. PMID 8058476 DOI: 10.1007/BF00585943 |
0.526 |
|
1994 |
Maccaferri G, Janigro D, Lazzari A, DiFrancesco D. Cesium prevents maintenance of long-term depression in rat hippocampal CA1 neurons. Neuroreport. 5: 1813-6. PMID 7827339 DOI: 10.1097/00001756-199409080-00032 |
0.601 |
|
1994 |
DiFrancesco D, Mangoni M. Modulation of single hyperpolarization-activated channels (i(f)) by cAMP in the rabbit sino-atrial node. The Journal of Physiology. 474: 473-82. PMID 7516974 DOI: 10.1113/Jphysiol.1994.Sp020038 |
0.53 |
|
1993 |
Hundal SP, DiFrancesco D, Mangoni M, Brammar WJ, Conley EC. An isoform of the cGMP-gated retinal photoreceptor channel gene expressed in the sinoatrial node (pacemaker) region of rabbit heart. Biochemical Society Transactions. 21: 119S. PMID 8359375 DOI: 10.1042/bst021119s |
0.389 |
|
1993 |
Maccaferri G, Mangoni M, Lazzari A, DiFrancesco D. Properties of the hyperpolarization-activated current in rat hippocampal CA1 pyramidal cells. Journal of Neurophysiology. 69: 2129-36. PMID 7688802 DOI: 10.1152/Jn.1993.69.6.2129 |
0.678 |
|
1993 |
DiFrancesco D. Pacemaker mechanisms in cardiac tissue. Annual Review of Physiology. 55: 455-72. PMID 7682045 DOI: 10.1146/annurev.ph.55.030193.002323 |
0.406 |
|
1992 |
DiFrancesco D, Ducouret P, Robinson R. Differential effects of ACh on cardiac pacemaker cells. Trends in Neurosciences. 15: 249-50. PMID 1381117 DOI: 10.1016/0166-2236(92)90059-H |
0.335 |
|
1992 |
Cui J, Mandel G, DiFrancesco D, Kline RP, Pennefather P, Datyner NB, Haspel HC, Cohen IS. Expression and characterization of a canine hippocampal inwardly rectifying K+ current in Xenopus oocytes. The Journal of Physiology. 457: 229-46. PMID 1338458 DOI: 10.1113/Jphysiol.1992.Sp019375 |
0.301 |
|
1992 |
Noble D, Denyer JC, Brown HF, DiFrancesco D. Reciprocal role of the inward currents ib, Na and i(f) in controlling and stabilizing pacemaker frequency of rabbit sino-atrial node cells. Proceedings. Biological Sciences / the Royal Society. 250: 199-207. PMID 1283636 DOI: 10.1098/rspb.1992.0150 |
0.435 |
|
1992 |
DiFRANCESCO D, Zaza A. The Cardiac Pacemaker Current if Journal of Cardiovascular Electrophysiology. 3: 334-344. DOI: 10.1111/J.1540-8167.1992.Tb00978.X |
0.541 |
|
1991 |
Difrancesco D. Generation and control of cardiac pacing the pacemaker current. Trends in Cardiovascular Medicine. 1: 250-5. PMID 21239304 DOI: 10.1016/1050-1738(91)90030-I |
0.449 |
|
1991 |
DiFrancesco D, Porciatti F, Janigro D, Maccaferri G, Mangoni M, Tritella T, Chang F, Cohen IS. Block of the cardiac pacemaker current (If) in the rabbit sino-atrial node and in canine Purkinje fibres by 9-amino-1,2,3,4-tetrahydroacridine. PflüGers Archiv : European Journal of Physiology. 417: 611-5. PMID 2057325 DOI: 10.1007/Bf00372959 |
0.694 |
|
1991 |
DiFrancesco D, Porciatti F, Cohen IS. The effects of manganese and barium on the cardiac pacemaker current, if, in rabbit sino-atrial node myocytes. Experientia. 47: 449-52. PMID 2044699 DOI: 10.1007/BF01959940 |
0.371 |
|
1991 |
DiFrancesco D. The contribution of the 'pacemaker' current (if) to generation of spontaneous activity in rabbit sino-atrial node myocytes. The Journal of Physiology. 434: 23-40. PMID 2023118 DOI: 10.1113/Jphysiol.1991.Sp018457 |
0.484 |
|
1991 |
Zaza A, Maccaferri G, Mangoni M, DiFrancesco D. Intracellular calcium does not directly modulate cardiac pacemaker (if) channels. PflüGers Archiv : European Journal of Physiology. 419: 662-4. PMID 1724077 DOI: 10.1007/Bf00370312 |
0.699 |
|
1991 |
DiFrancesco D, Tortora P. Direct activation of cardiac pacemaker channels by intracellular cyclic AMP. Nature. 351: 145-7. PMID 1709448 DOI: 10.1038/351145a0 |
0.523 |
|
1990 |
DIFRANCESCO D. The hyperpolarization-activated F-channel Cell Biology International Reports. 14: 40. DOI: 10.1016/0309-1651(90)90268-4 |
0.32 |
|
1989 |
DiFrancesco D, Ducouret P, Robinson RB. Muscarinic modulation of cardiac rate at low acetylcholine concentrations. Science (New York, N.Y.). 243: 669-71. PMID 2916119 DOI: 10.1126/Science.2916119 |
0.469 |
|
1989 |
Mazzanti M, DiFrancesco D. Intracellular Ca modulates K-inward rectification in cardiac myocytes. PflüGers Archiv : European Journal of Physiology. 413: 322-4. PMID 2717377 DOI: 10.1007/BF00581824 |
0.441 |
|
1988 |
DiFrancesco D, Tromba C. Inhibition of the hyperpolarization-activated current (if) induced by acetylcholine in rabbit sino-atrial node myocytes. The Journal of Physiology. 405: 477-91. PMID 3255798 DOI: 10.1113/Jphysiol.1988.Sp017343 |
0.44 |
|
1988 |
DiFrancesco D, Tromba C. Muscarinic control of the hyperpolarization-activated current (if) in rabbit sino-atrial node myocytes. The Journal of Physiology. 405: 493-510. PMID 2475609 DOI: 10.1113/Jphysiol.1988.Sp017344 |
0.426 |
|
1987 |
DiFrancesco D, Tromba C. Acetylcholine inhibits activation of the cardiac hyperpolarizing-activated current, if. PflüGers Archiv : European Journal of Physiology. 410: 139-42. PMID 2825112 DOI: 10.1007/BF00581906 |
0.424 |
|
1987 |
DiFrancesco D. The pacemaker current in the sinus node. European Heart Journal. 8: 19-23. PMID 2454189 DOI: 10.1093/Eurheartj/8.Suppl_L.19 |
0.488 |
|
1986 |
DiFrancesco D, Ferroni A, Mazzanti M, Tromba C. Properties of the hyperpolarizing-activated current (if) in cells isolated from the rabbit sino-atrial node. The Journal of Physiology. 377: 61-88. PMID 2432247 DOI: 10.1113/jphysiol.1986.sp016177 |
0.472 |
|
1986 |
DiFrancesco D. Characterization of single pacemaker channels in cardiac sino-atrial node cells. Nature. 324: 470-3. PMID 2431323 DOI: 10.1038/324470a0 |
0.541 |
|
1985 |
DiFrancesco D, Ferroni A, Visentin S, Zaza A. Cadmium-induced blockade of the cardiac fast Na channels in calf Purkinje fibres. Proceedings of the Royal Society of London. Series B, Biological Sciences. 223: 475-84. PMID 2580310 DOI: 10.1098/Rspb.1985.0013 |
0.425 |
|
1985 |
DiFrancesco D, Noble D. A model of cardiac electrical activity incorporating ionic pumps and concentration changes. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 307: 353-98. PMID 2578676 DOI: 10.1098/Rstb.1985.0001 |
0.404 |
|
1985 |
DiFrancesco D. The cardiac hyperpolarizing-activated current, if. Origins and developments. Progress in Biophysics and Molecular Biology. 46: 163-83. PMID 2418458 DOI: 10.1016/0079-6107(85)90008-2 |
0.43 |
|
1984 |
DiFrancesco D. Properties of the cardiac pacemaker (if) current. Bollettino Della Società Italiana Di Biologia Sperimentale. 60: 29-33. PMID 6466486 |
0.328 |
|
1984 |
DiFrancesco D. Characterization of the pace-maker current kinetics in calf Purkinje fibres. The Journal of Physiology. 348: 341-67. PMID 6325672 DOI: 10.1113/jphysiol.1984.sp015114 |
0.448 |
|
1984 |
DiFrancesco D, Ferroni A, Visentin S. Barium-induced blockade of the inward rectifier in calf Purkinje fibres. PflüGers Archiv : European Journal of Physiology. 402: 446-53. PMID 6097875 DOI: 10.1007/BF00583946 |
0.408 |
|
1983 |
DiFrancesco D, Ferroni A. Delayed activation of the cardiac pacemaker current and its dependence on conditioning pre-hyperpolarizations. PflüGers Archiv : European Journal of Physiology. 396: 265-7. PMID 6302637 DOI: 10.1007/BF00587866 |
0.325 |
|
1983 |
Hart G, Noble D, DiFrancesco D. Implications of electrogenic Na/Ca exchange in mammalian heart: Computer model Journal of Molecular and Cellular Cardiology. 15: 83-83. DOI: 10.1016/0022-2828(83)91021-0 |
0.32 |
|
1982 |
DiFrancesco D. Block and activation of the pace-maker channel in calf purkinje fibres: effects of potassium, caesium and rubidium. The Journal of Physiology. 329: 485-507. PMID 6292407 DOI: 10.1113/Jphysiol.1982.Sp014315 |
0.46 |
|
1981 |
DiFrancesco D. A study of the ionic nature of the pace-maker current in calf Purkinje fibres. The Journal of Physiology. 314: 377-93. PMID 6273534 DOI: 10.1113/Jphysiol.1981.Sp013714 |
0.473 |
|
1981 |
DiFrancesco D. A new interpretation of the pace-maker current in calf Purkinje fibres. The Journal of Physiology. 314: 359-76. PMID 6273533 DOI: 10.1113/Jphysiol.1981.Sp013713 |
0.466 |
|
1980 |
Brown H, DiFrancesco D, Noble D, Noble S. The contribution of potassium accumulation to outward currents in frog atrium. The Journal of Physiology. 306: 127-49. PMID 7463357 DOI: 10.1113/Jphysiol.1980.Sp013388 |
0.387 |
|
1980 |
Brown H, Difrancesco D. Voltage-clamp investigations of membrane currents underlying pace-maker activity in rabbit sino-atrial node. The Journal of Physiology. 308: 331-51. PMID 7230019 DOI: 10.1113/Jphysiol.1980.Sp013474 |
0.449 |
|
1980 |
DiFrancesco D, Ojeda C. Properties of the current if in the sino-atrial node of the rabbit compared with those of the current iK, in Purkinje fibres. The Journal of Physiology. 308: 353-67. PMID 6262501 |
0.34 |
|
1980 |
DiFrancesco D, Noma A, Trautwein W. Separation of current induced by potassium accumulation from acetylcholine-induced relaxation current in the rabbit S-A node. PflüGers Archiv : European Journal of Physiology. 387: 83-90. PMID 6253876 DOI: 10.1007/BF00584257 |
0.38 |
|
1979 |
DiFrancesco D, McNaughton PA. The effects of calcium on outward membrane currents in the cardiac Purkinje fibre. The Journal of Physiology. 289: 347-73. PMID 458668 DOI: 10.1113/jphysiol.1979.sp012741 |
0.402 |
|
1979 |
Brown HF, DiFrancesco D, Noble SJ. How does adrenaline accelerate the heart? Nature. 280: 235-6. PMID 450140 DOI: 10.1038/280235a0 |
0.474 |
|
1979 |
Brown H, Difrancesco D, Noble S. Cardiac pacemaker oscillation and its modulation by autonomic transmitters. The Journal of Experimental Biology. 81: 175-204. PMID 315983 |
0.413 |
|
1978 |
DiFrancesco D, Ohba M. Dependence of the apparent reversal potential for the pace-maker current iK2 on its degree of activation in cardiac Purkinje fibres [proceedings]. The Journal of Physiology. 280: 73P-74P. PMID 690937 |
0.34 |
|
Low-probability matches (unlikely to be authored by this person) |
2004 |
DiFrancesco D. Pacemaker Channels and Normal Automaticity Cardiac Electrophysiology: Fourth Edition. 103-111. DOI: 10.1016/B0-7216-0323-8/50015-4 |
0.299 |
|
2019 |
DiFrancesco D. Comparing pathways for long-term heart rate modulation by the funny current. The Journal of General Physiology. PMID 31431492 DOI: 10.1085/jgp.201912409 |
0.295 |
|
2019 |
Benzoni P, Campostrini G, Landi S, Bertini V, Marchina E, Iascone M, Ahlberg G, Olesen MS, Crescini E, Mora C, Bisleri G, Muneretto C, Ronca R, Presta M, Poliani PL, ... ... DiFrancesco D, et al. Human iPSC modeling of a familial form of atrial fibrillation reveals a gain of function of If and ICaL in patient-derived cardiomyocytes. Cardiovascular Research. PMID 31504264 DOI: 10.1093/cvr/cvz217 |
0.292 |
|
2011 |
Quinn TA, Granite S, Allessie MA, Antzelevitch C, Bollensdorff C, Bub G, Burton RA, Cerbai E, Chen PS, Delmar M, Difrancesco D, Earm YE, Efimov IR, Egger M, Entcheva E, et al. Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): standardised reporting for model reproducibility, interoperability, and data sharing. Progress in Biophysics and Molecular Biology. 107: 4-10. PMID 21745496 DOI: 10.1016/J.Pbiomolbio.2011.07.001 |
0.292 |
|
2017 |
Gambini E, Perrucci GL, Bassetti B, Spaltro G, Campostrini G, Lionetti MC, Pilozzi A, Martinelli F, Faruggia A, DiFrancesco D, Barbuti A, Pompilio G. Preferential myofibroblast differentiation of cardiac mesenchymal progenitor cells in the presence of atrial fibrillation. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 29245016 DOI: 10.1016/j.trsl.2017.11.003 |
0.288 |
|
2017 |
Atkinson A, Bucchi A, Piantoni C, Difrancesco D, Baruscotti M, Boyett M, Dobrzynski H. P1582Molecular basis of cardiac pacemaker ageing in mouse Ep Europace. 19: iii335-iii335. DOI: 10.1093/ehjci/eux158.208 |
0.288 |
|
2013 |
Scavone A, Capilupo D, Mazzocchi N, Crespi A, Zoia S, Campostrini G, Bucchi A, Milanesi R, Baruscotti M, Benedetti S, Antonini S, Messina G, DiFrancesco D, Barbuti A. Embryonic stem cell-derived CD166+ precursors develop into fully functional sinoatrial-like cells. Circulation Research. 113: 389-98. PMID 23753573 DOI: 10.1161/CIRCRESAHA.113.301283 |
0.288 |
|
2009 |
DiFrancesco D. More seafood to control heart rate? Heart Rhythm : the Official Journal of the Heart Rhythm Society. 6: 1493-4. PMID 19968930 DOI: 10.1016/j.hrthm.2009.08.019 |
0.284 |
|
2015 |
Baruscotti M, Bucchi A, Milanesi R, Paina M, Barbuti A, Gnecchi-Ruscone T, Bianco E, Vitali-Serdoz L, Cappato R, DiFrancesco D. A gain-of-function mutation in the cardiac pacemaker HCN4 channel increasing cAMP sensitivity is associated with familial Inappropriate Sinus Tachycardia. European Heart Journal. PMID 26553542 DOI: 10.1093/eurheartj/ehv582 |
0.282 |
|
1992 |
DIFRANCESCO D. Camp-induced control of cardiac pacemaker current Pharmacological Research. 26: 2. DOI: 10.1016/1043-6618(92)90716-O |
0.277 |
|
1992 |
DiFrancesco D, Zaza A. The cardiac pacemaker current i(f) Journal of Cardiovascular Electrophysiology. 3: 334-344. |
0.274 |
|
2017 |
Yavari A, Bellahcene M, Bucchi A, Sirenko S, Pinter K, Herring N, Jung JJ, Tarasov KV, Sharpe EJ, Wolfien M, Czibik G, Steeples V, Ghaffari S, Nguyen C, Stockenhuber A, ... ... DiFrancesco D, et al. Mammalian γ2 AMPK regulates intrinsic heart rate. Nature Communications. 8: 1258. PMID 29097735 DOI: 10.1038/S41467-017-01342-5 |
0.272 |
|
1989 |
Cohen IS, DiFrancesco D, Mulrine NK, Pennefather P. Internal and external K+ help gate the inward rectifier. Biophysical Journal. 55: 197-202. PMID 2930821 DOI: 10.1016/S0006-3495(89)82792-4 |
0.271 |
|
1990 |
Porciatti F, DiFrancesco D. High Na permeability of L-type Ca channels in isolated rabbit SA node cells Journal of Physiology. 426: 18P. |
0.271 |
|
2010 |
Barbuti A, Bucchi A, Baruscotti M, Difrancesco D. The "Funny" Pacemaker Current Novel Therapeutic Targets For Antiarrhythmic Drugs. 59-99. DOI: 10.1002/9780470561416.ch3 |
0.265 |
|
2017 |
Campostrini G, Bonzanni M, Lissoni A, Bazzini C, Milanesi R, Vezzoli E, Francolini M, Baruscotti M, Bucchi A, Rivolta I, Fantini M, Severi S, Cappato R, Crotti L, J Schwartz P, ... DiFrancesco D, et al. The expression of the rare caveolin-3 variant T78M alters cardiac ion channels function and membrane excitability. Cardiovascular Research. 113: 1256-1265. PMID 28898996 DOI: 10.1093/Cvr/Cvx122 |
0.265 |
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2016 |
Costantino S, Bonzanni M, Legchenko E, Paneni F, Mitchell K, Berrino L, Schwarzwald C, Volpe M, Luscher T, Cosentino F, Napoli A, Landi S, Bucchi A, Vernillo G, Baruscotti M, ... ... Difrancesco D, et al. Epigenetics in Cardiac Health and Disease225miR-218 and mi-R34a drive persistent myocardial oxidative stress by targeting chromatin remodelers DNMT3b and SIRT1: new mechanistic insights in diabetic cardiomyopathy226Effects of miRNAs modulated by endurance training on cardiomyocyte excitability227Differential transcriptome and microRNA expression signatures in the healthy heart (RV vs. LV) and the failing, pressure-overloaded right ventricle (SuHx model) Cardiovascular Research. 111: S43-S43. DOI: 10.1093/cvr/cvw128 |
0.264 |
|
1990 |
DiFrancesco D. Current If and the control of cardiac pacemaking Journal of Molecular and Cellular Cardiology. 22: x. DOI: 10.1016/0022-2828(90)91491-O |
0.263 |
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2017 |
Meraviglia V, Benzoni P, Landi S, Murano C, Langione M, Motta BM, Baratto S, Silipigni R, Di Segni M, Pramstaller PP, DiFrancesco D, Gazzerro E, Barbuti A, Rossini A. Generation of human induced pluripotent stem cells (EURACi001-A, EURACi002-A, EURACi003-A) from peripheral blood mononuclear cells of three patients carrying mutations in the CAV3 gene. Stem Cell Research. 27: 25-29. PMID 29304398 DOI: 10.1016/j.scr.2017.12.012 |
0.262 |
|
2015 |
Re A, Nanni S, Aiello A, Granata S, Colussi C, Campostrini G, Spallotta F, Mattiussi S, Pantisano V, D'Angelo C, Biroccio A, Rossini A, Barbuti A, DiFrancesco D, Trimarchi F, et al. Anacardic acid and thyroid hormone enhance cardiomyocytes production from undifferentiated mouse ES cells along functionally distinct pathways. Endocrine. PMID 26547215 DOI: 10.1007/s12020-015-0751-2 |
0.26 |
|
2006 |
DiFrancesco D. Cardiac Pacemaker (If) Current: Physiological and Pharmacological Properties Hospital Chronicles. 1: 151-155. DOI: 10.2015/Hc.V1I1 |
0.257 |
|
1990 |
Chang F, Gao J, Tromba C, Cohen I, DiFrancesco D. Acetylcholine reverses effects of beta-agonists on pacemaker current in canine cardiac Purkinje fibers but has no direct action. A difference between primary and secondary pacemakers. Circulation Research. 66: 633-6. PMID 1968362 DOI: 10.1161/01.Res.66.3.633 |
0.255 |
|
1979 |
DiFrancesco D, Noma A, Trautwein W. Kinetics and magnitude of the time-dependent potassium current in the rabbit sinoatrial node: effect of external potassium. PflüGers Archiv : European Journal of Physiology. 381: 271-9. PMID 574637 DOI: 10.1007/BF00583259 |
0.255 |
|
2024 |
Porro A, Saponaro A, Castelli R, Introini B, Hafez Alkotob A, Ranjbari G, Enke U, Kusch J, Benndorf K, Santoro B, DiFrancesco D, Thiel G, Moroni A. A high affinity switch for cAMP in the HCN pacemaker channels. Nature Communications. 15: 843. PMID 38287019 DOI: 10.1038/s41467-024-45136-y |
0.247 |
|
1979 |
DiFrancesco D, Ohba M, Ojeda C. Measurement and significance of the reversal potential for the pace-maker current (iK2) in sheep Purkinje fibres. The Journal of Physiology. 297: 135-62. PMID 536907 |
0.246 |
|
2011 |
Pisoni G, D'Amelio P, Sassi F, Manarolla G, Scaccabarozzi L, Locatelli C, Mazzocchi N, Baruscotti M, DiFrancesco D, Moroni P. Multinucleated giant cells with an osteoclast phenotype derived from caprine peripheral blood mononuclear cells. Veterinary Journal (London, England : 1997). 189: 361-3. PMID 20822938 DOI: 10.1016/j.tvjl.2010.07.016 |
0.241 |
|
1980 |
DiFrancesco D, Noble D. The time course of potassium current following potassium accumulation in frog atrium: analytical solutions using a linear approximation. The Journal of Physiology. 306: 151-73. PMID 7463358 |
0.238 |
|
2018 |
Campostrini G, DiFrancesco JC, Castellotti B, Milanesi R, Gnecchi-Ruscone T, Bonzanni M, Bucchi A, Baruscotti M, Ferrarese C, Franceschetti S, Canafoglia L, Ragona F, Freri E, Labate A, Gambardella A, ... ... DiFrancesco D, et al. A Loss-of-Function Mutation Associated With Familial Benign Myoclonic Epilepsy in Infancy Causes Increased Neuronal Excitability. Frontiers in Molecular Neuroscience. 11: 269. PMID 30127718 DOI: 10.3389/fnmol.2018.00269 |
0.232 |
|
2019 |
Saponaro A, Cantini F, Porro A, Bucchi A, DiFrancesco D, Maione V, Laskowski M, Mesirca P, Mangoni M, Thiel G, Banci L, Santoro B, Moroni A. Developing Synthetic Peptides to Regulate Native HCN Channels Biophysical Journal. 116: 302a. DOI: 10.1016/J.Bpj.2018.11.1638 |
0.219 |
|
2016 |
Bartolucci C, Ravagli E, Bucchi A, Baruscotti M, Difrancesco D, Severi S. Rate-adapted dynamic-clamp of the funny current in sinoatrial pacemaker cells Computing in Cardiology. 42: 1-4. DOI: 10.1109/CIC.2015.7408571 |
0.217 |
|
2019 |
Frosio A, Molla D, Bertoli G, Bazzini C, Milanesi R, Gennaro F, Barbuti A, Bucchi A, Moretti L, Marchese P, DiFrancesco D, Baruscotti M. Abstract 808: Functional Characterization of a Novel Scn5a Mutation Associated With the Brugada Syndrome Circulation Research. 125. DOI: 10.1161/res.125.suppl_1.808 |
0.214 |
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2023 |
DiFrancesco D, Noble D. Silvio Weidmann: laying the foundations for unravelling the mechanism of heart rhythm. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 378: 20220161. PMID 37122226 DOI: 10.1098/rstb.2022.0161 |
0.21 |
|
1979 |
DiFrancesco D, Noble D. The influence of voltage non-uniformity on the determination of Erev for iK2. The Journal of Physiology. 297: 158-62. PMID 536908 |
0.206 |
|
2021 |
Zhang S, Wang Y, Yu M, Shang Y, Chang Y, Zhao H, Kang Y, Zhao L, Xu L, Zhao X, Difrancesco D, Baruscotti M, Wang Y. Discovery of Herbacetin as a Novel SGK1 Inhibitor to Alleviate Myocardial Hypertrophy. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2101485. PMID 34761560 DOI: 10.1002/advs.202101485 |
0.194 |
|
2023 |
Krumbach JH, Bauer D, Sharifzadeh AS, Saponaro A, Lautenschläger R, Lange K, Rauh O, DiFrancesco D, Moroni A, Thiel G, Hamacher K. Alkali metal cations modulate the geometry of different binding sites in HCN4 selectivity filter for permeation or block. The Journal of General Physiology. 155. PMID 37523352 DOI: 10.1085/jgp.202313364 |
0.192 |
|
2021 |
Piantoni C, Carnevali L, Molla D, Barbuti A, DiFrancesco D, Bucchi A, Baruscotti M. Age-Related Changes in Cardiac Autonomic Modulation and Heart Rate Variability in Mice. Frontiers in Neuroscience. 15: 617698. PMID 34084126 DOI: 10.3389/fnins.2021.617698 |
0.191 |
|
1991 |
Chang F, Cohen IS, DiFrancesco D, Rosen MR, Tromba C. Effects of protein kinase inhibitors on canine Purkinje fibre pacemaker depolarization and the pacemaker current i(f). The Journal of Physiology. 440: 367-84. PMID 1804968 DOI: 10.1113/Jphysiol.1991.Sp018713 |
0.191 |
|
2020 |
D'Souza A, Wang Y, Anderson C, Bucchi A, Barsucotti M, Olieslagers S, Mesirca P, Johnsen AB, Mastitskaya S, Ni H, Zhang Y, Black N, Cox C, Wegner S, Bano-Otalora B, ... ... DiFrancesco D, et al. A circadian clock in the sinus node mediates day-night rhythms in Hcn4 and heart rate. Heart Rhythm. PMID 33278629 DOI: 10.1016/j.hrthm.2020.11.026 |
0.184 |
|
2012 |
Perez-Pomares JM, Ruiz-Villalba A, Ziogas A, Segovia JC, Ehrbar M, Munoz-Chapuli R, De La Rosa A, Dominguez JN, Hove-Madsen L, Sankova B, Sedmera D, Franco D, Aranega Jimenez A, Babaeva G, Chizh N, ... ... Difrancesco D, et al. Poster session 2 Cardiovascular Research. 93: S52-S87. DOI: 10.1093/Cvr/Cvr334 |
0.181 |
|
1979 |
Brown HF, DiFrancesco D, Noble SJ. Adrenaline action on rabbit sino-atrial node Journal of Physiology. 31P-32P. PMID 469766 |
0.162 |
|
1978 |
DiFrancesco D, Eisner DA, Lederer WJ. Low-potassium inotropy in cardiac muscle [proceedings]. The Journal of Physiology. 284: 138P-139P. PMID 731484 |
0.138 |
|
2024 |
Benndorf K, DiFrancesco D. Missing validation of key features in HCN single-channel recordings. Proceedings of the National Academy of Sciences of the United States of America. 121: e2400523121. PMID 38588429 DOI: 10.1073/pnas.2400523121 |
0.12 |
|
1981 |
Brown H, DiFrancesco D, Kimura J, Noble S. Caesium: A useful tool for investigating sino-atrial (S-A) node pace-making Journal of Physiology. 54P. |
0.119 |
|
1978 |
Noma A, DiFrancesco D, Trautwein W. Dose-response curve for acetylcholine (ACh) and carbamylcholine (CCh) in the rabbit SA-node Pflugers Archiv European Journal of Physiology. 377: R4. |
0.101 |
|
2018 |
Bonzanni M, DiFrancesco JC, Milanesi R, Campostrini G, Castellotti B, Bucchi A, Baruscotti M, Ferrarese C, Franceschetti S, Canafoglia L, Ragona F, Freri E, Labate A, Gambardella A, Costa C, ... ... DiFrancesco D, et al. A novel de novo HCN1 loss-of-function mutation in genetic generalized epilepsy causing increased neuronal excitability. Neurobiology of Disease. PMID 29936235 DOI: 10.1016/j.nbd.2018.06.012 |
0.088 |
|
1979 |
DiFrancesco D, Noble D. On the time course of extracellular ion concentration changes in frog atrium [proceedings]. The Journal of Physiology. 296: 80P. PMID 529149 |
0.079 |
|
2014 |
Noble D, DiFrancesco D, Zancani D. LEONARDO DA VINCI AND THE ORIGIN OF SEMEN. Notes and Records of the Royal Society of London. 68: 391-402. PMID 27494016 |
0.055 |
|
1986 |
DiFrancesco D, Pinhas AR. The nickel promoted 1,3-migration of an sp2 center: Ring expansion of a vinylcyclobutene Journal of Organic Chemistry. 51: 2098-2102. |
0.03 |
|
2002 |
DiFrancesco DJ, Talwani M. Time lapse gravity gradiometry for reservoir monitoring Seg Technical Program Expanded Abstracts. 21: 787-790. DOI: 10.1190/1.1817377 |
0.024 |
|
2014 |
Noble D, Difrancesco D, Zancani D. Leonardo da Vinci and the origin of semen Notes and Records of the Royal Society. 68: 391-402. DOI: 10.1098/rsnr.2014.0021 |
0.013 |
|
2000 |
DiFrancesco DT. Comprehensive health care review is legislative priority. New Jersey Medicine : the Journal of the Medical Society of New Jersey. 97: 27-8. PMID 10832362 |
0.013 |
|
2009 |
Difrancesco D, Grierson A, Kaputa D, Meyer T. Gravity gradiometer systems -advances and challenges Geophysical Prospecting. 57: 615-623. DOI: 10.1111/j.1365-2478.2008.00764.x |
0.012 |
|
2011 |
DiFrancesco DA, Young N. Seeing climate change: The visual construction of global warming in Canadian national print media Cultural Geographies. 18: 517-536. DOI: 10.1177/1474474010382072 |
0.012 |
|
2011 |
Kohrn SB, Bonet C, DiFrancesco D, Gibson H. Geothermal exploration using gravity gradiometry - A Salton Sea example Transactions - Geothermal Resources Council. 35: 1699-1702. |
0.011 |
|
2010 |
Dimova I, Hlushchuk R, Makanya A, Djonov V, Theurl M, Schgoer W, Albrecht K, Beer A, Patsch JR, Schratzberger P, Mahata S, Kirchmair R, Didie M, Christalla P, Rau T, ... ... Difrancesco D, et al. Saturday, 17 July 2010 Cardiovascular Research. 87: S45-S88. DOI: 10.1093/cvr/cvq174 |
0.01 |
|
2001 |
DiFrancesco DT. Senate passes health care reform package. New Jersey Medicine : the Journal of the Medical Society of New Jersey. 98: 17-8. PMID 11198108 |
0.01 |
|
2001 |
Romaides AJ, Battis JC, Sands RW, Zorn A, Benson DO, DiFrancesco DJ. A comparison of gravimetric techniques for measuring subsurface void signals Journal of Physics D: Applied Physics. 34: 433-443. DOI: 10.1088/0022-3727/34/3/331 |
0.01 |
|
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