Connie M. Krawczyk, Ph.D. - Publications

Affiliations: 
2002 University of Toronto, Toronto, ON, Canada 
Area:
Genetics, Molecular Biology, Immunology

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Luda KM, Longo J, Kitchen-Goosen SM, Duimstra LR, Ma EH, Watson MJ, Oswald BM, Fu Z, Madaj Z, Kupai A, Dickson BM, DeCamp LM, Dahabieh MS, Compton SE, Teis R, ... ... Krawczyk CM, et al. Ketolysis drives CD8 T cell effector function through effects on histone acetylation. Immunity. PMID 37516105 DOI: 10.1016/j.immuni.2023.07.002  0.401
2023 Ma EH, Dahabieh MS, DeCamp LM, Kaymak I, Kitchen-Goosen SM, Roy DG, Verway MJ, Johnson RM, Samborska B, Scullion CA, Steadman M, Vos M, Roddy TP, Krawczyk CM, Williams KS, et al. C metabolite tracing reveals glutamine and acetate as critical in vivo fuels for CD8 T cells. Biorxiv : the Preprint Server For Biology. PMID 37333111 DOI: 10.1101/2023.06.09.544407  0.33
2021 Pardy RD, Valbon SF, Cordeiro B, Krawczyk CM, Richer MJ. An epidemic Zika virus isolate suppresses antiviral immunity by disrupting antigen presentation pathways. Nature Communications. 12: 4051. PMID 34193875 DOI: 10.1038/s41467-021-24340-0  0.33
2020 Guak H, Krawczyk CM. Implications of cellular metabolism for immune cell migration. Immunology. PMID 32920838 DOI: 10.1111/imm.13260  0.302
2020 Roy DG, Chen J, Mamane V, Ma EH, Muhire BM, Sheldon RD, Shorstova T, Koning R, Johnson RM, Esaulova E, Williams KS, Hayes S, Steadman M, Samborska B, Swain A, ... ... Krawczyk CM, et al. Methionine Metabolism Shapes T Helper Cell Responses through Regulation of Epigenetic Reprogramming. Cell Metabolism. 31: 250-266.e9. PMID 32023446 DOI: 10.1016/J.Cmet.2020.01.006  0.351
2019 Ma EH, Verway MJ, Johnson RM, Roy DG, Steadman M, Hayes S, Williams KS, Sheldon RD, Samborska B, Kosinski PA, Kim H, Griss T, Faubert B, Condotta SA, Krawczyk CM, et al. Metabolic Profiling Using Stable Isotope Tracing Reveals Distinct Patterns of Glucose Utilization by Physiologically Activated CD8 T Cells. Immunity. 51: 856-870.e5. PMID 31747582 DOI: 10.1016/J.Immuni.2019.09.003  0.362
2018 Won SY, Hunt K, Guak H, Hasaj B, Charland N, Landry N, Ward BJ, Krawczyk CM. Characterization of the innate stimulatory capacity of plant-derived virus-like particles bearing influenza hemagglutinin. Vaccine. PMID 30448064 DOI: 10.1016/j.vaccine.2018.10.099  0.343
2018 Smith LK, Boukhaled GM, Condotta SA, Mazouz S, Guthmiller JJ, Vijay R, Butler NS, Bruneau J, Shoukry NH, Krawczyk CM, Richer MJ. Interleukin-10 Directly Inhibits CD8+ T Cell Function by Enhancing N-Glycan Branching to Decrease Antigen Sensitivity. Immunity. PMID 29396160 DOI: 10.1016/J.Immuni.2018.01.006  0.337
2017 Ma EH, Bantug G, Griss T, Condotta S, Johnson RM, Samborska B, Mainolfi N, Suri V, Guak H, Balmer ML, Verway MJ, Raissi TC, Tsui H, Boukhaled G, Henriques da Costa S, ... ... Krawczyk CM, et al. Serine Is an Essential Metabolite for Effector T Cell Expansion. Cell Metabolism. 25: 482. PMID 28178570 DOI: 10.1016/j.cmet.2017.01.014  0.381
2017 Ma EH, Bantug G, Griss T, Condotta S, Johnson RM, Samborska B, Mainolfi N, Suri V, Guak H, Balmer ML, Verway MJ, Raissi TC, Tsui H, Boukhaled G, Henriques da Costa S, ... ... Krawczyk CM, et al. Serine Is an Essential Metabolite for Effector T Cell Expansion. Cell Metabolism. PMID 28111214 DOI: 10.1016/J.Cmet.2016.12.011  0.404
2015 Van Den Ham KM, Shio MT, Rainone A, Fournier S, Krawczyk CM, Olivier M. Iron prevents the development of experimental cerebral malaria by attenuating CXCR3-mediated T cell chemotaxis. Plos One. 10: e0118451. PMID 25768944 DOI: 10.1371/Journal.Pone.0118451  0.342
2015 Blagih J, Coulombe F, Vincent EE, Dupuy F, Galicia-Vázquez G, Yurchenko E, Raissi TC, van der Windt GJ, Viollet B, Pearce EL, Pelletier J, Piccirillo CA, Krawczyk CM, Divangahi M, Jones RG. The energy sensor AMPK regulates T cell metabolic adaptation and effector responses in vivo. Immunity. 42: 41-54. PMID 25607458 DOI: 10.1016/J.Immuni.2014.12.030  0.387
2014 Contreras I, Estrada JA, Guak H, Martel C, Borjian A, Ralph B, Shio MT, Fournier S, Krawczyk CM, Olivier M. Impact of Leishmania mexicana infection on dendritic cell signaling and functions. Plos Neglected Tropical Diseases. 8: e3202. PMID 25255446 DOI: 10.1371/Journal.Pntd.0003202  0.32
2012 Blagih J, Krawczyk CM, Jones RG. LKB1 and AMPK: central regulators of lymphocyte metabolism and function. Immunological Reviews. 249: 59-71. PMID 22889215 DOI: 10.1111/j.1600-065X.2012.01157.x  0.448
2011 Gervais FG, Sawyer N, Stocco R, Hamel M, Krawczyk C, Sillaots S, Denis D, Wong E, Wang Z, Gallant M, Abraham WM, Slipetz D, Crackower MA, O'Neill GP. Pharmacological characterization of MK-7246, a potent and selective CRTH2 (chemoattractant receptor-homologous molecule expressed on T-helper type 2 cells) antagonist. Molecular Pharmacology. 79: 69-76. PMID 20943773 DOI: 10.1124/mol.110.068585  0.316
2010 Krawczyk CM, Holowka T, Sun J, Blagih J, Amiel E, DeBerardinis RJ, Cross JR, Jung E, Thompson CB, Jones RG, Pearce EJ. Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation. Blood. 115: 4742-9. PMID 20351312 DOI: 10.1182/Blood-2009-10-249540  0.307
2009 Carvalho L, Sun J, Kane C, Marshall F, Krawczyk C, Pearce EJ. Review series on helminths, immune modulation and the hygiene hypothesis: mechanisms underlying helminth modulation of dendritic cell function. Immunology. 126: 28-34. PMID 19120496 DOI: 10.1111/j.1365-2567.2008.03008.x  0.347
2007 Jones RG, Bui T, White C, Madesh M, Krawczyk CM, Lindsten T, Hawkins BJ, Kubek S, Frauwirth KA, Wang YL, Conway SJ, Roderick HL, Bootman MD, Shen H, Foskett JK, et al. The proapoptotic factors Bax and Bak regulate T Cell proliferation through control of endoplasmic reticulum Ca(2+) homeostasis. Immunity. 27: 268-80. PMID 17692540 DOI: 10.1016/J.Immuni.2007.05.023  0.349
2007 Krawczyk CM, Shen H, Pearce EJ. Memory CD4 T cells enhance primary CD8 T-cell responses. Infection and Immunity. 75: 3556-60. PMID 17438031 DOI: 10.1128/Iai.00086-07  0.356
2005 Jones RG, Saibil SD, Pun JM, Elford AR, Bonnard M, Pellegrini M, Arya S, Parsons ME, Krawczyk CM, Gerondakis S, Yeh WC, Woodgett JM, Boothby MR, Ohashi PS. NF-κB couples protein kinase B/Akt signaling to distinct survival pathways and the regulation of lymphocyte homeostasis in vivo Journal of Immunology. 175: 3790-3799. PMID 16148125  0.351
2005 Krawczyk CM, Jones RG, Atfteld A, Bachmaier K, Arya S, Odermatt B, Ohashi PS, Penninger JM. Differential control of CD28-regulated in vivo immunity by the E3 ligase Cbl-b Journal of Immunology. 174: 1472-1478. PMID 15661906 DOI: 10.4049/Jimmunol.174.3.1472  0.613
2004 Jeon MS, Atfield A, Venuprasad K, Krawczyk C, Sarao R, Elly C, Yang C, Arya S, Bachmaier K, Su L, Bouchard D, Jones R, Gronski M, Ohashi P, Wada T, et al. Essential role of the E3 ubiquitin ligase Cbl-b in T cell anergy induction Immunity. 21: 167-177. PMID 15308098 DOI: 10.1016/J.Immuni.2004.07.013  0.628
2003 Pearce EL, Mullen AC, Martins GA, Krawczyk CM, Hutchins AS, Zediak VP, Banica M, DiCioccio CB, Gross DA, Mao CA, Shen H, Cereb N, Yang SY, Lindsten T, Rossant J, et al. Control of effector CD8+ T cell function by the transcription factor Eomesodermin. Science (New York, N.Y.). 302: 1041-3. PMID 14605368 DOI: 10.1126/Science.1090148  0.441
2003 Griffiths EK, Sanchez O, Mill P, Krawczyk C, Hojilla CV, Rubin E, Nau MM, Khokha R, Lipkowitz S, Hui CC, Penninger JM. Cbl-3-deficient mice exhibit normal epithelial development. Molecular and Cellular Biology. 23: 7708-18. PMID 14560016 DOI: 10.1128/Mcb.23.21.7708-7718.2003  0.674
2003 Hara H, Wada T, Bakal C, Kozieradzki I, Suzuki S, Suzuki N, Nghiem M, Griffiths EK, Krawczyk C, Bauer B, D'Acquisto F, Ghosh S, Yeh WC, Baier G, Rottapel R, et al. The MAGUK family protein CARD11 is essential for lymphocyte activation. Immunity. 18: 763-75. PMID 12818158 DOI: 10.1016/S1074-7613(03)00148-1  0.715
2002 Jones RG, Elford AR, Parsons MJ, Wu L, Krawczyk CM, Yeh WC, Hakem R, Rottapel R, Woodgett JR, Ohashi PS. CD28-dependent activation of protein kinase B/Akt blocks Fas-mediated apoptosis by preventing death-inducing signaling complex assembly. The Journal of Experimental Medicine. 196: 335-48. PMID 12163562 DOI: 10.1084/Jem.20020307  0.538
2002 Krawczyk C, Oliveira-dos-Santos A, Sasaki T, Griffiths E, Ohashi PS, Snapper S, Alt F, Penninger JM. Vav1 controls integrin clustering and MHC/peptide-specific cell adhesion to antigen-presenting cells. Immunity. 16: 331-43. PMID 11911819 DOI: 10.1016/S1074-7613(02)00291-1  0.705
2001 Griffiths EK, Krawczyk C, Kong YY, Raab M, Hyduk SJ, Bouchard D, Chan VS, Kozieradzki I, Oliveira-Dos-Santos AJ, Wakeham A, Ohashi PS, Cybulsky MI, Rudd CE, Penninger JM. Positive regulation of T cell activation and integrin adhesion by the adapter Fyb/Slap. Science (New York, N.Y.). 293: 2260-3. PMID 11567140 DOI: 10.1126/Science.1063397  0.73
2001 Krawczyk C, Penninger JM. Molecular controls of antigen receptor clustering and autoimmunity. Trends in Cell Biology. 11: 212-20. PMID 11316610 DOI: 10.1016/S0962-8924(01)01981-X  0.687
2001 Irie-Sasaki J, Sasaki T, Matsumoto W, Opavsky A, Cheng M, Welstead G, Griffiths E, Krawczyk C, Richardson CD, Aitken K, Iscove N, Koretzky G, Johnson P, Liu P, Rothstein DM, et al. CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling. Nature. 409: 349-54. PMID 11201744 DOI: 10.1038/35053086  0.689
2001 Krawczyk C, Penninger JM. Molecular motors involved in T cell receptor clusterings. Journal of Leukocyte Biology. 69: 317-330. DOI: 10.1189/Jlb.69.3.317  0.618
2000 Krawczyk C, Bachmaier K, Sasaki T, Jones RG, Snapper SB, Bouchard D, Kozieradzki I, Ohashi PS, Alt FW, Penninger JM. Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells. Immunity. 13: 463-73. PMID 11070165 DOI: 10.1016/S1074-7613(00)00046-7  0.671
2000 Bachmaier K, Krawczyk C, Kozieradzki I, Kong YY, Sasaki T, Oliveira-dos-Santos A, Mariathasan S, Bouchard D, Wakeham A, Itie A, Le J, Ohashi PS, Sarosi I, Nishina H, Lipkowitz S, et al. Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b. Nature. 403: 211-6. PMID 10646608 DOI: 10.1038/35003228  0.671
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