Shabaana A. Khader - Publications

Affiliations: 
Immunology University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Immunology, Cell Biology

118 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Gupta A, Thirunavukkarasu S, Rangel-Moreno J, Ahmed M, Swanson RV, Mbandi SK, Smrcka AV, Kaushal D, Scriba TJ, Khader SA. Phospholipase C epsilon-1 (PLCƐ1) mediates macrophage activation and protection against tuberculosis. Infection and Immunity. e0049523. PMID 38451080 DOI: 10.1128/iai.00495-23  0.403
2024 Das S, Chauhan KS, Ahmed M, Akter S, Lu L, Colonna M, Khader SA. Lung type 3 innate lymphoid cells respond early following infection. Mbio. e0329923. PMID 38407132 DOI: 10.1128/mbio.03299-23  0.429
2024 Chauhan KS, Dunlap MD, Akter S, Gupta A, Ahmed M, Rosa BA, Dela Peña NB, Mitreva M, Khader SA. NF-κB signaling deficiency in CD11c-expressing phagocytes mediates early inflammatory responses and enhances Mycobacterium tuberculosis control. The Journal of Infectious Diseases. PMID 38324907 DOI: 10.1093/infdis/jiae060  0.323
2024 Ahmed M, Farris E, Swanson RV, Das S, Yang Y, Martin T, Khader SA. Saponin TQL1055 adjuvant-containing vaccine confers protection upon challenge in mice. Human Vaccines & Immunotherapeutics. 20: 2302070. PMID 38190806 DOI: 10.1080/21645515.2024.2302070  0.362
2023 Bobba S, Howard NC, Das S, Ahmed M, Khan N, Marchante I, Barreiro LB, Sanz J, Divangahi M, Khader SA. infection drives differential responses in the bone marrow hematopoietic stem and progenitor cells. Infection and Immunity. e0020123. PMID 37754680 DOI: 10.1128/iai.00201-23  0.309
2023 Bobba S, Howard NC, Das S, Ahmed M, Tang L, Thirunavukkarasu S, Larsen MH, Mathema B, Divangahi M, Khader SA. carrying the rifampicin drug-resistance-conferring mutation H445Y is associated with suppressed immunity through type I interferons. Mbio. e0094623. PMID 37682004 DOI: 10.1128/mbio.00946-23  0.377
2023 Bobba S, Khader SA. Rifampicin drug resistance and host immunity in tuberculosis: more than meets the eye. Trends in Immunology. 44: 712-723. PMID 37543504 DOI: 10.1016/j.it.2023.07.003  0.311
2023 Thirunavukkarasu S, Ahmed M, Rosa BA, Boothby M, Cho SH, Rangel-Moreno J, Mbandi SK, Schreiber V, Gupta A, Zúñiga J, Mitreva M, Kaushal D, Scriba TJ, Khader SA. Poly(ADP)ribose polymerase 9 mediates early protection against Mycobacterium tuberculosis infection by regulating type I IFN production. The Journal of Clinical Investigation. PMID 37200107 DOI: 10.1172/JCI158630  0.357
2022 Scott NR, Thirunavukkarasu S, Rangel-Moreno J, Griggs DW, Khader SA. CWHM-12, an Antagonist of Integrin-Mediated Transforming Growth Factor-Beta Activation Confers Protection During Early Infection in Mice. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. PMID 35914102 DOI: 10.1089/jir.2022.0027  0.303
2022 Rahimi RA, Cho JL, Jakubzick CV, Khader SA, Lambrecht BN, Lloyd CM, Molofsky AB, Talbot S, Bonham CA, Drake WP, Sperling AI, Singer BD. Advancing Lung Immunology Research: An Official American Thoracic Society Workshop Report. American Journal of Respiratory Cell and Molecular Biology. 67: e1-18. PMID 35776495 DOI: 10.1165/rcmb.2022-0167ST  0.323
2022 Downey J, Randolph HE, Pernet E, Tran KA, Khader SA, King IL, Barreiro LB, Divangahi M. Mitochondrial cyclophilin D promotes disease tolerance by licensing NK cell development and IL-22 production against influenza virus. Cell Reports. 39: 110974. PMID 35732121 DOI: 10.1016/j.celrep.2022.110974  0.466
2022 Akter S, Chauhan KS, Dunlap MD, Choreño-Parra JA, Lu L, Esaulova E, Zúñiga J, Artyomov MN, Kaushal D, Khader SA. Mycobacterium tuberculosis infection drives a type I IFN signature in lung lymphocytes. Cell Reports. 39: 110983. PMID 35732116 DOI: 10.1016/j.celrep.2022.110983  0.401
2022 Singh DK, Aladyeva E, Das S, Singh B, Esaulova E, Swain A, Ahmed M, Cole J, Moodley C, Mehra S, Schlesinger LS, Artyomov MN, Khader SA, Kaushal D. Myeloid cell interferon responses correlate with clearance of SARS-CoV-2. Nature Communications. 13: 679. PMID 35115549 DOI: 10.1038/s41467-022-28315-7  0.325
2022 Urusova DV, Merriman JA, Gupta A, Chen L, Mathema B, Caparon MG, Khader SA. Rifampin resistance mutations in the rpoB gene of Enterococcus faecalis impact host macrophage cytokine production. Cytokine. 151: 155788. PMID 35030469 DOI: 10.1016/j.cyto.2021.155788  0.368
2021 Singh B, Singh DK, Ganatra SR, Escobedo RA, Khader S, Schlesinger LS, Kaushal D, Mehra S. Myeloid-Derived Suppressor Cells Mediate T Cell Dysfunction in Nonhuman Primate TB Granulomas. Mbio. e0318921. PMID 34903057 DOI: 10.1128/mbio.03189-21  0.417
2021 Sharan R, Ganatra SR, Bucsan AN, Cole J, Singh DK, Alvarez X, Gough M, Alvarez C, Blakley A, Ferdin J, Thippeshappa R, Singh B, Escobedo R, Shivanna V, Dick EJ, ... ... Khader SA, et al. Antiretroviral therapy timing impacts latent tuberculosis infection reactivation in a tuberculosis/simian immunodeficiency virus coinfection model. The Journal of Clinical Investigation. PMID 34855621 DOI: 10.1172/JCI153090  0.366
2021 Choreño-Parra JA, Dunlap MD, Swanson R, Jiménez-Álvarez LA, Muñoz-Torrico M, Guzmán-Beltrán S, Zúñiga J, Khader SA. CXCL17 Is Dispensable during Hypervirulent HN878 Infection in Mice. Immunohorizons. 5: 752-759. PMID 34561226 DOI: 10.4049/immunohorizons.2100048  0.373
2021 Singh D, Aladyeva E, Das S, Singh B, Esaulova E, Swain A, Ahmed M, Cole J, Moodley C, Mehra S, Schlesinger L, Artyomov M, Khader S, Kaushal D. Myeloid cell interferon responses correlate with clearance of SARS-CoV-2. Research Square. PMID 34282414 DOI: 10.21203/rs.3.rs-664507/v1  0.328
2021 Das S, Marin ND, Esaulova E, Ahmed M, Swain A, Rosa BA, Mitreva M, Rangel-Moreno J, Netea MG, Barreiro LB, Divangahi M, Artyomov MN, Kaushal D, Khader SA. Lung Epithelial Signaling Mediates Early Vaccine-Induced CD4 T Cell Activation and Control. Mbio. e0146821. PMID 34253059 DOI: 10.1128/mBio.01468-21  0.416
2021 Chumakov K, Avidan MS, Benn CS, Bertozzi SM, Blatt L, Chang AY, Jamison DT, Khader SA, Kottilil S, Netea MG, Sparrow A, Gallo RC. Old vaccines for new infections: Exploiting innate immunity to control COVID-19 and prevent future pandemics. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34006644 DOI: 10.1073/pnas.2101718118  0.375
2021 Choreño-Parra JA, Jiménez-Álvarez LA, Cruz-Lagunas A, Rodríguez-Reyna TS, Ramírez-Martínez G, Sandoval-Vega M, Hernández-García DL, Choreño-Parra EM, Balderas-Martínez YI, Martinez-Sánchez ME, Márquez-García E, Sciutto E, Moreno-Rodríguez J, Barreto-Rodríguez JO, Vázquez-Rojas H, ... ... Khader SA, et al. Clinical and Immunological Factors That Distinguish COVID-19 From Pandemic Influenza A(H1N1). Frontiers in Immunology. 12: 593595. PMID 33995342 DOI: 10.3389/fimmu.2021.593595  0.411
2021 Rosa BA, Ahmed M, Singh DK, Choreño-Parra JA, Cole J, Jiménez-Álvarez LA, Rodríguez-Reyna TS, Singh B, Gonzalez O, Carrion R, Schlesinger LS, Martin J, Zúñiga J, Mitreva M, Kaushal D, ... Khader SA, et al. IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection. Communications Biology. 4: 290. PMID 33674719 DOI: 10.1038/s42003-021-01829-4  0.313
2020 Esaulova E, Das S, Singh DK, Choreño-Parra JA, Swain A, Arthur L, Rangel-Moreno J, Ahmed M, Singh B, Gupta A, Fernández-López LA, de la Luz Garcia-Hernandez M, Bucsan A, Moodley C, Mehra S, ... ... Khader SA, et al. The immune landscape in tuberculosis reveals populations linked to disease and latency. Cell Host & Microbe. PMID 33340449 DOI: 10.1016/j.chom.2020.11.013  0.422
2020 Singh DK, Singh B, Ganatra SR, Gazi M, Cole J, Thippeshappa R, Alfson KJ, Clemmons E, Gonzalez O, Escobedo R, Lee TH, Chatterjee A, Goez-Gazi Y, Sharan R, Gough M, ... ... Khader SA, et al. Responses to acute infection with SARS-CoV-2 in the lungs of rhesus macaques, baboons and marmosets. Nature Microbiology. PMID 33340034 DOI: 10.1038/s41564-020-00841-4  0.33
2020 Rosa BA, Ahmed M, Singh DK, Choreno-Parra JA, Cole J, Jimenez-Alvarez LA, Rodriguez-Reyna TS, Singh B, Golzalez O, Carrion R, Schlesinger LS, Martin J, Zuniga J, Mitreva M, Khader SA, et al. IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection. Biorxiv : the Preprint Server For Biology. PMID 32793903 DOI: 10.1101/2020.08.06.239798  0.351
2020 Nemes E, Khader SA, Swanson RV, Hanekom WA. Targeting Unconventional Host Components for Vaccination-Induced Protection Against TB. Frontiers in Immunology. 11: 1452. PMID 32793199 DOI: 10.3389/Fimmu.2020.01452  0.486
2020 Dunlap MD, Prince OA, Rangel-Moreno J, Thomas KA, Scordo JM, Torrelles JB, Cox J, Steyn AJC, Zúñiga J, Kaushal D, Khader SA. Formation of Lung Inducible Bronchus Associated Lymphoid Tissue Is Regulated by Expressed Determinants. Frontiers in Immunology. 11: 1325. PMID 32695111 DOI: 10.3389/Fimmu.2020.01325  0.471
2020 Ganatra SR, Bucsan AN, Alvarez X, Kumar S, Chatterjee A, Quezada M, Fish AI, Singh DK, Singh B, Sharan R, Lee TH, Shanmugasundaram U, Velu V, Khader SA, Mehra S, et al. Anti-retroviral therapy does not reduce tuberculosis reactivation in a tuberculosis-HIV co-infection model. The Journal of Clinical Investigation. PMID 32544085 DOI: 10.1172/Jci136502  0.41
2020 Sharan R, Bucşan AN, Ganatra S, Paiardini M, Mohan M, Mehra S, Khader SA, Kaushal D. Chronic Immune Activation in TB/HIV Co-infection: (Trends in Microbiology 28, XXX-XXX; 2020). Trends in Microbiology. PMID 32482557 DOI: 10.1016/J.Tim.2020.05.006  0.4
2020 Li LX, Hole CR, Rangel-Moreno J, Khader SA, Doering TL. evades pulmonary immunity by modulating xylose precursor transport. Infection and Immunity. PMID 32423915 DOI: 10.1128/Iai.00288-20  0.548
2020 Dorhoi A, Kotzé LA, Berzofsky JA, Sui Y, Gabrilovich DI, Garg A, Hafner R, Khader SA, Schaible UE, Kaufmann SH, Walzl G, Lutz MB, Mahon RN, Ostrand-Rosenberg S, Bishai W, et al. Therapies for tuberculosis and AIDS: myeloid-derived suppressor cells in focus. The Journal of Clinical Investigation. PMID 32420917 DOI: 10.1172/Jci136288  0.464
2020 Sharan R, Bucşan AN, Ganatra S, Paiardini M, Mohan M, Mehra S, Khader SA, Kaushal D. Chronic Immune Activation in TB/HIV Co-infection. Trends in Microbiology. PMID 32417227 DOI: 10.1016/J.Tim.2020.03.015  0.404
2020 Howard NC, Khader SA. Immunometabolism during Mycobacterium tuberculosis Infection. Trends in Microbiology. PMID 32409147 DOI: 10.1016/J.Tim.2020.04.010  0.385
2020 Choreño-Parra JA, Thirunavukkarasu S, Zúñiga J, Khader SA. The protective and pathogenic roles of CXCL17 in human health and disease: Potential in respiratory medicine. Cytokine & Growth Factor Reviews. PMID 32345516 DOI: 10.1016/J.Cytogfr.2020.04.004  0.338
2020 Scott NR, Swanson RV, Al-Hammadi N, Domingo-Gonzalez R, Rangel-Moreno J, Kriel BA, Bucsan AN, Das S, Ahmed M, Mehra S, Treerat P, Cruz-Lagunas A, Jimenez-Alvarez L, Muñoz-Torrico M, Bobadilla-Lozoya K, ... ... Khader S, et al. S100A8/A9 regulates CD11b expression and neutrophil recruitment during chronic tuberculosis. The Journal of Clinical Investigation. PMID 32134742 DOI: 10.1172/Jci130546  0.397
2020 Ahmed M, Thirunavukkarasu S, Rosa BA, Thomas KA, Das S, Rangel-Moreno J, Lu L, Mehra S, Mbandi SK, Thackray LB, Diamond MS, Murphy KM, Means T, Martin J, Kaushal D, ... ... Khader SA, et al. Immune correlates of tuberculosis disease and risk translate across species. Science Translational Medicine. 12. PMID 31996462 DOI: 10.1126/Scitranslmed.Aay0233  0.454
2019 Alberto Choreño-Parra J, Bobba S, Rangel-Moreno J, Ahmed M, Mehra S, Rosa B, Martin J, Mitreva M, Kaushal D, Zúñiga J, Khader SA. Mycobacterium tuberculosis HN878 infection induces human-like B cell follicles in mice. The Journal of Infectious Diseases. PMID 31832640 DOI: 10.1093/Infdis/Jiz663  0.503
2019 Bucşan AN, Chatterjee A, Singh DK, Foreman TW, Lee TH, Threeton B, Kirkpatrick MG, Ahmed M, Golden N, Alvarez X, Hoxie JA, Mehra S, Rengarajan J, Khader SA, Kaushal D. Mechanisms of reactivation of latent tuberculosis infection due to SIV co-infection. The Journal of Clinical Investigation. PMID 31479428 DOI: 10.1172/Jci125810  0.427
2019 Khader SA, Divangahi M, Hanekom W, Hill PC, Maeurer M, Makar KW, Mayer-Barber KD, Mhlanga MM, Nemes E, Schlesinger LS, van Crevel R, Vankalayapati R, Xavier RJ, Netea MG. Targeting innate immunity for tuberculosis vaccination. The Journal of Clinical Investigation. 129: 3482-3491. PMID 31478909 DOI: 10.1172/Jci128877  0.485
2019 Bucsan AN, Mehra S, Khader SA, Kaushal D. The current state of animal models and genomic approaches towards identifying and validating molecular determinants of Mycobacterium tuberculosis infection and tuberculosis disease. Pathogens and Disease. PMID 31381766 DOI: 10.1093/Femspd/Ftz037  0.444
2019 Ardain A, Domingo-Gonzalez R, Das S, Kazer SW, Howard NC, Singh A, Ahmed M, Nhamoyebonde S, Rangel-Moreno J, Ogongo P, Lu L, Ramsuran D, de la Luz Garcia-Hernandez M, Ulland TK, Darby M, ... ... Khader SA, et al. Publisher Correction: Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis. Nature. PMID 31337923 DOI: 10.1038/S41586-019-1458-Y  0.428
2019 Ardain A, Domingo-Gonzalez R, Das S, Kazer SW, Howard NC, Singh A, Ahmed M, Nhamoyebonde S, Rangel-Moreno J, Ogongo P, Lu L, Ramsuran D, de la Luz Garcia-Hernandez M, K Ulland T, Darby M, ... ... Khader SA, et al. Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis. Nature. PMID 31168092 DOI: 10.1038/S41586-019-1276-2  0.539
2019 Bucsan AN, Rout N, Foreman TW, Khader SA, Rengarajan J, Kaushal D. Mucosal-activated invariant T cells do not exhibit significant lung recruitment and proliferation profiles in macaques in response to infection with Mycobacterium tuberculosis CDC1551. Tuberculosis (Edinburgh, Scotland). PMID 31072689 DOI: 10.1016/J.Tube.2019.04.006  0.499
2019 Marin ND, Dunlap MD, Kaushal D, Khader SA. Friend or Foe: The Protective and Pathological Roles of Inducible Bronchus-Associated Lymphoid Tissue in Pulmonary Diseases. Journal of Immunology (Baltimore, Md. : 1950). 202: 2519-2526. PMID 31010841 DOI: 10.4049/Jimmunol.1801135  0.401
2019 Corleis B, Bucsan AN, Deruaz M, Vrbanac VD, Lisanti-Park AC, Gates SJ, Linder AH, Paer JM, Olson GS, Bowman BA, Schiff AE, Medoff BD, Tager AM, Luster AD, Khader SA, et al. HIV-1 and SIV Infection Are Associated with Early Loss of Lung Interstitial CD4+ T Cells and Dissemination of Pulmonary Tuberculosis. Cell Reports. 26: 1409-1418.e5. PMID 30726727 DOI: 10.1016/J.Celrep.2019.01.021  0.388
2019 Khader SA, Thirunavukkarasu S. The Tale of IL-12 and IL-23: A Paradigm Shift. Journal of Immunology (Baltimore, Md. : 1950). 202: 629-630. PMID 30670577 DOI: 10.4049/Jimmunol.1801603  0.502
2018 Howard NC, Marin ND, Ahmed M, Rosa BA, Martin J, Bambouskova M, Sergushichev A, Loginicheva E, Kurepina N, Rangel-Moreno J, Chen L, Kreiswirth BN, Klein RS, Balada-Llasat JM, Torrelles JB, ... ... Khader SA, et al. Publisher Correction: Mycobacterium tuberculosis carrying a rifampicin drug resistance mutation reprograms macrophage metabolism through cell wall lipid changes. Nature Microbiology. PMID 30327492 DOI: 10.1038/S41564-018-0281-9  0.389
2018 Howard NC, Marin ND, Ahmed M, Rosa BA, Martin J, Bambouskova M, Sergushichev A, Loginicheva E, Kurepina N, Rangel-Moreno J, Chen L, Kreiswirth BN, Klein RS, Balada-Llasat JM, Torrelles JB, ... ... Khader SA, et al. Mycobacterium tuberculosis carrying a rifampicin drug resistance mutation reprograms macrophage metabolism through cell wall lipid changes. Nature Microbiology. PMID 30224802 DOI: 10.1038/S41564-018-0245-0  0.42
2018 Dunlap MD, Howard N, Das S, Scott N, Ahmed M, Prince O, Rangel-Moreno J, Rosa BA, Martin J, Kaushal D, Kaplan G, Mitreva M, Kim KW, Randolph GJ, Khader SA. A novel role for C-C motif chemokine receptor 2 during infection with hypervirulent Mycobacterium tuberculosis. Mucosal Immunology. PMID 30115997 DOI: 10.1038/S41385-018-0071-Y  0.463
2017 Monin L, Mehta S, Elsegeiny W, Gopal R, McAleer JP, Oury TD, Kolls J, Khader SA. Aspergillus fumigatus pre-exposure worsens pathology and improves control of Mycobacterium abscessus pulmonary infection in mice. Infection and Immunity. PMID 29263106 DOI: 10.1128/Iai.00859-17  0.395
2017 Gautam US, Foreman TW, Bucsan AN, Veatch AV, Alvarez X, Adekambi T, Golden NA, Gentry KM, Doyle-Meyers LA, Russell-Lodrigue KE, Didier PJ, Blanchard JL, Kousoulas KG, Lackner AA, Kalman D, ... ... Khader SA, et al. In vivo inhibition of tryptophan catabolism reorganizes the tuberculoma and augments immune-mediated control of Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 29255022 DOI: 10.1073/Pnas.1711373114  0.483
2017 Domingo-Gonzalez R, Das S, Griffiths KL, Ahmed M, Bambouskova M, Gopal R, Gondi S, Muñoz-Torrico M, Salazar-Lezama MA, Cruz-Lagunas A, Jiménez-Álvarez L, Ramirez-Martinez G, Espinosa-Soto R, Sultana T, Lyons-Weiler J, ... ... Khader SA, et al. Interleukin-17 limits hypoxia-inducible factor 1α and development of hypoxic granulomas during tuberculosis. Jci Insight. 2. PMID 28978810 DOI: 10.1172/Jci.Insight.92973  0.583
2017 Srikanta DL, Hole CR, Williams M, Khader SA, Doering TL. RNAi screening reveals host CaMK4 as a regulator of cryptococcal uptake and pathogenesis. Infection and Immunity. PMID 28970273 DOI: 10.1128/Iai.00195-17  0.333
2017 Foreman TW, Veatch AV, LoBato DN, Didier PJ, Doyle-Meyers LA, Russell-Lodrigue KE, Lackner AA, Kousoulas KG, Khader SA, Kaushal D, Mehra S. Non-pathological infection of macaques by an attenuated mycobacterial vaccine is not reactivated in the setting of HIV coinfection. The American Journal of Pathology. PMID 28935575 DOI: 10.1016/J.Ajpath.2017.08.014  0.446
2017 Dunlap MD, Khader SA. Dancing with the Stars: Phenolic Glycolipids Partners with Macrophages. Cell Host & Microbe. 22: 249-251. PMID 28910627 DOI: 10.1016/J.Chom.2017.08.016  0.336
2017 Ahmed M, Smith DM, Hamouda T, Rangel-Moreno J, Fattom A, Khader SA. A novel nanoemulsion vaccine induces mucosal Interleukin-17 responses and confers protection upon Mycobacterium tuberculosis challenge in mice. Vaccine. PMID 28774560 DOI: 10.1016/J.Vaccine.2017.07.073  0.565
2017 Das S, Khader S. Yin and yang of interleukin-17 in host immunity to infection. F1000research. 6: 741. PMID 28713557 DOI: 10.12688/F1000Research.10862.1  0.604
2017 Eddens T, Elsegeiny W, Garcia-Hernadez ML, Castillo P, Trevejo-Nunez G, Serody K, Campfield BT, Khader SA, Chen K, Rangel-Moreno J, Kolls JK. Pneumocystis-Driven Inducible Bronchus-Associated Lymphoid Tissue Formation Requires Th2 and Th17 Immunity. Cell Reports. 18: 3078-3090. PMID 28355561 DOI: 10.1016/J.Celrep.2017.03.016  0.589
2017 Ahmed M, Jiao H, Domingo-Gonzalez R, Das S, Griffiths KL, Rangel-Moreno J, Nagarajan UM, Khader SA. Rationalized design of a mucosal vaccine protects against Mycobacterium tuberculosis challenge in mice. Journal of Leukocyte Biology. PMID 28258153 DOI: 10.1189/Jlb.4A0616-270R  0.526
2017 Treerat P, Prince O, Cruz-Lagunas A, Muñoz-Torrico M, Salazar-Lezama MA, Selman M, Fallert-Junecko B, Reinhardt TA, Alcorn JF, Kaushal D, Zuñiga J, Rangel-Moreno J, Kolls JK, Khader SA. Novel role for IL-22 in protection during chronic Mycobacterium tuberculosis HN878 infection. Mucosal Immunology. PMID 28247861 DOI: 10.1038/Mi.2017.15  0.644
2016 Griffiths KL, Ahmed M, Das S, Gopal R, Horne W, Connell TD, Moynihan KD, Kolls JK, Irvine DJ, Artyomov MN, Rangel-Moreno J, Khader SA. Targeting dendritic cells to accelerate T-cell activation overcomes a bottleneck in tuberculosis vaccine efficacy. Nature Communications. 7: 13894. PMID 28004802 DOI: 10.1038/Ncomms13894  0.482
2016 Domingo-Gonzalez R, Prince O, Cooper A, Khader SA. Cytokines and Chemokines in Mycobacterium tuberculosis Infection. Microbiology Spectrum. 4. PMID 27763255 DOI: 10.1128/Microbiolspec.Tbtb2-0018-2016  0.54
2016 Foreman TW, Mehra S, LoBato DN, Malek A, Alvarez X, Golden NA, Bucşan AN, Didier PJ, Doyle-Meyers LA, Russell-Lodrigue KE, Roy CJ, Blanchard J, Kuroda MJ, Lackner AA, Chan J, ... Khader SA, et al. CD4+ T-cell-independent mechanisms suppress reactivation of latent tuberculosis in a macaque model of HIV coinfection. Proceedings of the National Academy of Sciences of the United States of America. PMID 27601645 DOI: 10.1073/Pnas.1611987113  0.458
2016 Lampropoulou V, Sergushichev A, Bambouskova M, Nair S, Vincent EE, Loginicheva E, Cervantes-Barragan L, Ma X, Huang SC, Griss T, Weinheimer CJ, Khader S, Randolph GJ, Pearce EJ, Jones RG, et al. Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation. Cell Metabolism. PMID 27374498 DOI: 10.1016/J.Cmet.2016.06.004  0.337
2016 Griffiths KL, Villarreal DO, Weiner DB, Khader SA. A novel multivalent tuberculosis vaccine confers protection in a mouse model of tuberculosis. Human Vaccines & Immunotherapeutics. 0. PMID 27322875 DOI: 10.1080/21645515.2016.1197454  0.423
2016 Gish SR, Maier EJ, Haynes BC, Santiago-Tirado FH, Srikanta DL, Ma CZ, Li LX, Williams M, Crouch EC, Khader SA, Brent MR, Doering TL. Computational Analysis Reveals a Key Regulator of Cryptococcal Virulence and Determinant of Host Response. Mbio. 7. PMID 27094327 DOI: 10.1128/Mbio.00313-16  0.317
2015 Monin L, Griffiths KL, Lam WY, Gopal R, Kang DD, Ahmed M, Rajamanickam A, Cruz-Lagunas A, Zúñiga J, Babu S, Kolls JK, Mitreva M, Rosa BA, Ramos-Payan R, Morrison TE, ... ... Khader SA, et al. Helminth-induced arginase-1 exacerbates lung inflammation and disease severity in tuberculosis. The Journal of Clinical Investigation. PMID 26571397 DOI: 10.1172/Jci77378  0.523
2015 Kaushal D, Foreman TW, Gautam US, Alvarez X, Adekambi T, Rangel-Moreno J, Golden NA, Johnson AM, Phillips BL, Ahsan MH, Russell-Lodrigue KE, Doyle LA, Roy CJ, Didier PJ, Blanchard JL, ... ... Khader SA, et al. Mucosal vaccination with attenuated Mycobacterium tuberculosis induces strong central memory responses and protects against tuberculosis. Nature Communications. 6: 8533. PMID 26460802 DOI: 10.1038/Ncomms9533  0.452
2015 Mehra S, Foreman TW, Didier PJ, Ahsan MH, Hudock TA, Kissee R, Golden NA, Gautam US, Johnson AM, Alvarez X, Russell-Lodrigue KE, Doyle LA, Roy CJ, Niu T, Blanchard JL, ... Khader SA, et al. The DosR Regulon Modulates Adaptive Immunity and Is Essential for Mycobacterium tuberculosis Persistence. American Journal of Respiratory and Critical Care Medicine. 191: 1185-96. PMID 25730547 DOI: 10.1164/Rccm.201408-1502Oc  0.424
2015 Monin L, Griffiths KL, Slight S, Lin Y, Rangel-Moreno J, Khader SA. Immune requirements for protective Th17 recall responses to Mycobacterium tuberculosis challenge. Mucosal Immunology. 8: 1099-109. PMID 25627812 DOI: 10.1038/Mi.2014.136  0.836
2015 Phillips BL, Mehra S, Ahsan MH, Selman M, Khader SA, Kaushal D. LAG3 expression in active Mycobacterium tuberculosis infections. The American Journal of Pathology. 185: 820-33. PMID 25549835 DOI: 10.1016/J.Ajpath.2014.11.003  0.478
2014 Monin L, Khader SA. Chemokines in tuberculosis: the good, the bad and the ugly. Seminars in Immunology. 26: 552-8. PMID 25444549 DOI: 10.1016/J.Smim.2014.09.004  0.528
2014 Griffiths KL, Khader SA. Bringing in the cavalry: IL-26 mediates neutrophil recruitment to the lungs. American Journal of Respiratory and Critical Care Medicine. 190: 1079-80. PMID 25398102 DOI: 10.1164/Rccm.201410-1870Ed  0.513
2014 Gopal R, Monin L, Slight S, Uche U, Blanchard E, Fallert Junecko BA, Ramos-Payan R, Stallings CL, Reinhart TA, Kolls JK, Kaushal D, Nagarajan U, Rangel-Moreno J, Khader SA. Unexpected role for IL-17 in protective immunity against hypervirulent Mycobacterium tuberculosis HN878 infection. Plos Pathogens. 10: e1004099. PMID 24831696 DOI: 10.1371/Journal.Ppat.1004099  0.852
2014 Khader SA, Kolls JK. Editorial overview: Vaccines: Vaccines for infectious diseases: are we there yet? Current Opinion in Immunology. 28: ix-x. PMID 24735901 DOI: 10.1016/J.Coi.2014.03.005  0.319
2014 Madan-Lala R, Sia JK, King R, Adekambi T, Monin L, Khader SA, Pulendran B, Rengarajan J. Mycobacterium tuberculosis impairs dendritic cell functions through the serine hydrolase Hip1. Journal of Immunology (Baltimore, Md. : 1950). 192: 4263-72. PMID 24659689 DOI: 10.4049/Jimmunol.1303185  0.582
2014 Griffiths KL, Khader SA. Novel vaccine approaches for protection against intracellular pathogens. Current Opinion in Immunology. 28: 58-63. PMID 24608070 DOI: 10.1016/J.Coi.2014.02.003  0.425
2014 Gopal R, Rangel-Moreno J, Fallert Junecko BA, Mallon DJ, Chen K, Pociask DA, Connell TD, Reinhart TA, Alcorn JF, Ross TM, Kolls JK, Khader SA. Mucosal pre-exposure to Th17-inducing adjuvants exacerbates pathology after influenza infection. The American Journal of Pathology. 184: 55-63. PMID 24183780 DOI: 10.1016/J.Ajpath.2013.09.012  0.575
2013 Torres-García D, Cruz-Lagunas A, García-Sancho Figueroa MC, Fernández-Plata R, Baez-Saldaña R, Mendoza-Milla C, Barquera R, Carrera-Eusebio A, Ramírez-Bravo S, Campos L, Angeles J, Vargas-Alarcón G, Granados J, Gopal R, Khader SA, et al. Variants in toll-like receptor 9 gene influence susceptibility to tuberculosis in a Mexican population. Journal of Translational Medicine. 11: 220. PMID 24053111 DOI: 10.1186/1479-5876-11-220  0.385
2013 Gopal R, Monin L, Torres D, Slight S, Mehra S, McKenna KC, Fallert Junecko BA, Reinhart TA, Kolls J, Báez-Saldaña R, Cruz-Lagunas A, Rodríguez-Reyna TS, Kumar NP, Tessier P, Roth J, ... ... Khader SA, et al. S100A8/A9 proteins mediate neutrophilic inflammation and lung pathology during tuberculosis. American Journal of Respiratory and Critical Care Medicine. 188: 1137-46. PMID 24047412 DOI: 10.1164/Rccm.201304-0803Oc  0.785
2013 Slight SR, Monin L, Gopal R, Avery L, Davis M, Cleveland H, Oury TD, Rangel-Moreno J, Khader SA. IL-10 restrains il-17 to limit lung pathology characteristics following pulmonary infection with francisella tularensis live vaccine strain American Journal of Pathology. 183: 1397-1404. PMID 24007881 DOI: 10.1016/J.Ajpath.2013.07.008  0.846
2013 Gopal R, Khader SA. Vaccines against tuberculosis: moving forward with new concepts. Expert Review of Vaccines. 12: 829-31. PMID 23944644 DOI: 10.1586/14760584.2013.814836  0.445
2013 Obermajer N, Wong JL, Edwards RP, Chen K, Scott M, Khader S, Kolls JK, Odunsi K, Billiar TR, Kalinski P. Induction and stability of human Th17 cells require endogenous NOS2 and cGMP-dependent NO signaling. The Journal of Experimental Medicine. 210: 1433-445. PMID 23797095 DOI: 10.1084/Jem.20121277  0.585
2013 Monin L, Khader SA. B cells produce CXCL13 in lymphoid neogenesis during chronic obstructive pulmonary disease. The new kid on the block? American Journal of Respiratory and Critical Care Medicine. 187: 1162-4. PMID 23725611 DOI: 10.1164/Rccm.201303-0552Ed  0.437
2013 Gopal R, Rangel-Moreno J, Slight S, Lin Y, Nawar HF, Fallert Junecko BA, Reinhart TA, Kolls J, Randall TD, Connell TD, Khader SA. Interleukin-17-dependent CXCL13 mediates mucosal vaccine-induced immunity against tuberculosis. Mucosal Immunology. 6: 972-84. PMID 23299616 DOI: 10.1038/Mi.2012.135  0.829
2013 Slight SR, Rangel-Moreno J, Gopal R, Lin Y, Fallert Junecko BA, Mehra S, Selman M, Becerril-Villanueva E, Baquera-Heredia J, Pavon L, Kaushal D, Reinhart TA, Randall TD, Khader SA. CXCR5⁺ T helper cells mediate protective immunity against tuberculosis. The Journal of Clinical Investigation. 123: 712-26. PMID 23281399 DOI: 10.1172/Jci65728  0.808
2013 Hernández-Santos N, Huppler AR, Peterson AC, Khader SA, McKenna KC, Gaffen SL. Th17 cells confer long-term adaptive immunity to oral mucosal Candida albicans infections. Mucosal Immunology. 6: 900-10. PMID 23250275 DOI: 10.1038/Mi.2012.128  0.58
2013 Slight SR, Khader SA. Chemokines shape the immune responses to tuberculosis. Cytokine & Growth Factor Reviews. 24: 105-13. PMID 23168132 DOI: 10.1016/J.Cytogfr.2012.10.002  0.804
2013 Obermajer N, Wong JL, Edwards RP, Chen K, Scott M, Khader S, Kolls JK, Odunsi K, Billiar TR, Kalinski P. Development and stability of Th17 cells in ovarian cancer requires nitric oxide and endogenous NOS2 activity in cancer-associated CD4+ T cells Journal For Immunotherapy of Cancer. 1. DOI: 10.1186/2051-1426-1-S1-P146  0.554
2012 Guglani L, Gopal R, Rangel-Moreno J, Junecko BF, Lin Y, Berger T, Mak TW, Alcorn JF, Randall TD, Reinhart TA, Chan YR, Khader SA. Lipocalin 2 regulates inflammation during pulmonary mycobacterial infections. Plos One. 7: e50052. PMID 23185529 DOI: 10.1371/Journal.Pone.0050052  0.457
2012 Khader SA. Restraining IL-17: Del-1 deals the blow. Nature Immunology. 13: 433-5. PMID 22513326 DOI: 10.1038/Ni.2290  0.531
2012 Gopal R, Lin Y, Obermajer N, Slight S, Nuthalapati N, Ahmed M, Kalinski P, Khader SA. IL-23-dependent IL-17 drives Th1-cell responses following Mycobacterium bovis BCG vaccination. European Journal of Immunology. 42: 364-73. PMID 22101830 DOI: 10.1002/Eji.201141569  0.841
2011 Khader SA, Guglani L, Rangel-Moreno J, Gopal R, Junecko BA, Fountain JJ, Martino C, Pearl JE, Tighe M, Lin YY, Slight S, Kolls JK, Reinhart TA, Randall TD, Cooper AM. IL-23 is required for long-term control of Mycobacterium tuberculosis and B cell follicle formation in the infected lung. Journal of Immunology (Baltimore, Md. : 1950). 187: 5402-7. PMID 22003199 DOI: 10.4049/Jimmunol.1101377  0.834
2011 Slight SR, Lin Y, Messmer M, Khader SA. Francisella tularensis LVS-induced Interleukin-12 p40 cytokine production mediates dendritic cell migration through IL-12 Receptor β1. Cytokine. 55: 372-9. PMID 21669537 DOI: 10.1016/J.Cyto.2011.05.017  0.813
2011 Rangel-Moreno J, Carragher DM, de la Luz Garcia-Hernandez M, Hwang JY, Kusser K, Hartson L, Kolls JK, Khader SA, Randall TD. The development of inducible bronchus-associated lymphoid tissue depends on IL-17. Nature Immunology. 12: 639-46. PMID 21666689 DOI: 10.1038/Ni.2053  0.515
2011 Kang DD, Lin Y, Moreno JR, Randall TD, Khader SA. Profiling early lung immune responses in the mouse model of tuberculosis. Plos One. 6: e16161. PMID 21249199 DOI: 10.1371/Journal.Pone.0016161  0.523
2011 Kudva A, Scheller EV, Robinson KM, Crowe CR, Choi SM, Slight SR, Khader SA, Dubin PJ, Enelow RI, Kolls JK, Alcorn JF. Influenza A inhibits Th17-mediated host defense against bacterial pneumonia in mice. Journal of Immunology (Baltimore, Md. : 1950). 186: 1666-74. PMID 21178015 DOI: 10.4049/Jimmunol.1002194  0.821
2010 Khader SA, Gopal R. IL-17 in protective immunity to intracellular pathogens. Virulence. 1: 423-7. PMID 21178483 DOI: 10.4161/Viru.1.5.12862  0.641
2010 Rapaka RR, Ricks DM, Alcorn JF, Chen K, Khader SA, Zheng M, Plevy S, Bengtén E, Kolls JK. Conserved natural IgM antibodies mediate innate and adaptive immunity against the opportunistic fungus Pneumocystis murina. The Journal of Experimental Medicine. 207: 2907-19. PMID 21149550 DOI: 10.1084/Jem.20100034  0.412
2010 Kolls JK, Khader SA. The role of Th17 cytokines in primary mucosal immunity. Cytokine & Growth Factor Reviews. 21: 443-8. PMID 21095154 DOI: 10.1016/J.Cytogfr.2010.11.002  0.611
2010 Khader SA. Th17 cytokines: the good, the bad, and the unknown. Cytokine & Growth Factor Reviews. 21: 403-4. PMID 21075041 DOI: 10.1016/J.Cytogfr.2010.10.008  0.454
2010 Guglani L, Khader SA. Th17 cytokines in mucosal immunity and inflammation. Current Opinion in Hiv and Aids. 5: 120-7. PMID 20543588 DOI: 10.1097/Coh.0B013E328335C2F6  0.557
2010 Robinson RT, Khader SA, Martino CA, Fountain JJ, Teixeira-Coelho M, Pearl JE, Smiley ST, Winslow GM, Woodland DL, Walter MJ, Conejo-Garcia JR, Gubler U, Cooper AM. Mycobacterium tuberculosis infection induces il12rb1 splicing to generate a novel IL-12Rbeta1 isoform that enhances DC migration. The Journal of Experimental Medicine. 207: 591-605. PMID 20212068 DOI: 10.1084/Jem.20091085  0.625
2010 Lin Y, Slight SR, Khader SA. Th17 cytokines and vaccine-induced immunity. Seminars in Immunopathology. 32: 79-90. PMID 20112107 DOI: 10.1007/S00281-009-0191-2  0.844
2010 Gopal R, Lin Y, Khader SA. SS11-5 Role of interleukin-17 in immunity to intracellular pulmonary pathogens Cytokine. 52: 81. DOI: 10.1016/J.Cyto.2010.07.336  0.444
2009 Khader SA, Rangel-Moreno J, Fountain JJ, Martino CA, Reiley WW, Pearl JE, Winslow GM, Woodland DL, Randall TD, Cooper AM. In a murine tuberculosis model, the absence of homeostatic chemokines delays granuloma formation and protective immunity. Journal of Immunology (Baltimore, Md. : 1950). 183: 8004-14. PMID 19933855 DOI: 10.4049/Jimmunol.0901937  0.526
2009 Lin Y, Ritchea S, Logar A, Slight S, Messmer M, Rangel-Moreno J, Guglani L, Alcorn JF, Strawbridge H, Park SM, Onishi R, Nyugen N, Walter MJ, Pociask D, Randall TD, ... ... Khader SA, et al. Interleukin-17 is required for T helper 1 cell immunity and host resistance to the intracellular pathogen Francisella tularensis. Immunity. 31: 799-810. PMID 19853481 DOI: 10.1016/J.Immuni.2009.08.025  0.84
2009 Khader SA, Gaffen SL, Kolls JK. Th17 cells at the crossroads of innate and adaptive immunity against infectious diseases at the mucosa Mucosal Immunology. 2: 403-411. PMID 19587639 DOI: 10.1038/Mi.2009.100  0.619
2008 Cooper AM, Khader SA. The role of cytokines in the initiation, expansion, and control of cellular immunity to tuberculosis Immunological Reviews. 226: 191-204. PMID 19161425 DOI: 10.1111/J.1600-065X.2008.00702.X  0.657
2008 Robinson RT, Khader SA, Locksley RM, Lien E, Smiley ST, Cooper AM. Yersinia pestis evades TLR4-dependent induction of IL-12(p40)2 by dendritic cells and subsequent cell migration. Journal of Immunology (Baltimore, Md. : 1950). 181: 5560-7. PMID 18832714 DOI: 10.4049/Jimmunol.181.8.5560  0.509
2008 Khader SA, Cooper AM. IL-23 and IL-17 in tuberculosis Cytokine. 41: 79-83. PMID 18218322 DOI: 10.1016/J.Cyto.2007.11.022  0.663
2007 Cooper AM, Solache A, Khader SA. Interleukin-12 and tuberculosis: an old story revisited Current Opinion in Immunology. 19: 441-447. PMID 17702558 DOI: 10.1016/J.Coi.2007.07.004  0.579
2007 Khader SA, Bell GK, Pearl JE, Fountain JJ, Rangel-Moreno J, Cilley GE, Shen F, Eaton SM, Gaffen SL, Swain SL, Locksley RM, Haynes L, Randall TD, Cooper AM. IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge. Nature Immunology. 8: 369-77. PMID 17351619 DOI: 10.1038/Ni1449  0.576
2007 Cooper AM, Khader SA. IL-12p40: an inherently agonistic cytokine Trends in Immunology. 28: 33-38. PMID 17126601 DOI: 10.1016/J.It.2006.11.002  0.557
2006 Cruz A, Khader SA, Torrado E, Fraga A, Pearl JE, Pedrosa J, Cooper AM, Castro AG. Cutting edge: IFN-γ regulates the induction and expansion of IL-17-producing CD4 T cells during mycobacterial infection Journal of Immunology. 177: 1416-1420. PMID 16849446 DOI: 10.4049/Jimmunol.177.3.1416  0.6
2006 Khader SA, Partida-Sanchez S, Bell G, Jelley-Gibbs DM, Swain S, Pearl JE, Ghilardi N, DeSauvage FJ, Lund FE, Cooper AM. Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection Journal of Experimental Medicine. 203: 1805-1815. PMID 16818672 DOI: 10.1084/Jem.20052545  0.558
2005 Khader SA, Pearl JE, Sakamoto K, Gilmartin L, Bell GK, Jelley-Gibbs DM, Ghilardi N, deSauvage F, Cooper AM. IL-23 compensates for the absence of IL-12p70 and is essential for the IL-17 response during tuberculosis but is dispensable for protection and antigen-specific IFN-gamma responses if IL-12p70 is available. Journal of Immunology (Baltimore, Md. : 1950). 175: 788-95. PMID 16002675 DOI: 10.4049/Jimmunol.175.2.788  0.579
2004 Pearl JE, Khader SA, Solache A, Gilmartin L, Ghilardi N, DeSauvage F, Cooper AM. IL-27 signaling compromises control of bacterial growth in mycobacteria-infected mice Journal of Immunology. 173: 7490-7496. PMID 15585875 DOI: 10.4049/Jimmunol.173.12.7490  0.61
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