| Year |
Citation |
Score |
| 2023 |
Tacquard C, Tupin F, Magnenat S, Brouard N, Eckly A, Proamer F, Metz-Favre C, Stenger R, Piotin A, De Blay F, Ebo D, Elst J, Mertes PM, Hechler B. Human platelets do not possess the FcεRI and FcεRII receptors for IgE. Allergy. PMID 37897054 DOI: 10.1111/all.15935 |
0.479 |
|
| 2023 |
Brouard N, Pissenem-Rudwill F, Mouriaux C, Haas D, Galvanin A, Kientz D, Mangin PH, Isola H, Hechler B. Biochemical and functional characteristics of stored (double-dose) buffy-coat platelet concentrates treated with amotosalen and a prototype UVA light-emitting diode illuminator. Transfusion. 63: 1937-1950. PMID 37615493 DOI: 10.1111/trf.17519 |
0.305 |
|
| 2022 |
Feng M, Hechler B, Adam F, Gachet C, Eckly A, Kauskot A, Denis CV, Bryckaert M, Bobe R, Rosa JP. ADP receptor P2Y12 is the capstone of the cross-talk between Ca mobilization pathways dependent on Ca ATPases sarcoplasmic/endoplasmic reticulum type 3 and type 2b in platelets. Research and Practice in Thrombosis and Haemostasis. 7: 100004. PMID 36970741 DOI: 10.1016/j.rpth.2022.100004 |
0.518 |
|
| 2022 |
Tacquard C, Mouriaux C, Delabranche X, Bourdon C, Eckly A, Magnenat S, Sattler L, Gachet C, Mertes PM, Hechler B, Mangin PH. Platelet dysfunction and thrombus instability in flow conditions in patients with severe COVID-19. Thrombosis Research. 221: 137-148. PMID 36376109 DOI: 10.1016/j.thromres.2022.11.004 |
0.606 |
|
| 2022 |
El Mdawar MB, Maître B, Magnenat S, Tupin F, Jönsson F, Gachet C, de la Salle H, Hechler B. Platelet FcγRIIA-induced serotonin release exacerbates the severity of transfusion-related acute lung injury in mice. Blood Advances. 5: 4817-4830. PMID 34521102 DOI: 10.1182/bloodadvances.2021004336 |
0.6 |
|
| 2021 |
Rabouël Y, Magnenat S, Lefebvre F, Delabranche X, Gachet C, Hechler B. Transfusion of fresh washed platelets does not prevent experimental polymicrobial-induced septic shock in mice. Journal of Thrombosis and Haemostasis : Jth. 20: 449-460. PMID 34752015 DOI: 10.1111/jth.15583 |
0.633 |
|
| 2021 |
Rabouel Y, Magnenat S, Delabranche X, Gachet C, Hechler B. Platelet P2Y Receptor Deletion or Pharmacological Inhibition does not Protect Mice from Sepsis or Septic Shock. Th Open : Companion Journal to Thrombosis and Haemostasis. 5: e343-e352. PMID 34447900 DOI: 10.1055/s-0041-1733857 |
0.617 |
|
| 2021 |
Ahmed MU, Receveur N, Janus-Bell E, Mouriaux C, Gachet C, Jandrot-Perrus M, Hechler B, Gardiner EE, Mangin PH. Respective roles of Glycoprotein VI and FcγRIIA in the regulation of αIIbβ3-mediated platelet activation to fibrinogen, thrombus buildup, and stability. Research and Practice in Thrombosis and Haemostasis. 5: e12551. PMID 34263103 DOI: 10.1002/rth2.12551 |
0.657 |
|
| 2021 |
Isola H, Ravanat C, Rudwill F, Pongerard A, Haas D, Eckly A, Gachet C, Hechler B. Removal of citrate from PAS-III additive solution improves functional and biochemical characteristics of buffy-coat platelet concentrates stored for 7 days, with or without INTERCEPT pathogen reduction. Transfusion. PMID 33527430 DOI: 10.1111/trf.16280 |
0.562 |
|
| 2021 |
Godon O, Hechler B, Jönsson F. The role of IgG subclasses and platelets in experimental anaphylaxis. The Journal of Allergy and Clinical Immunology. PMID 33493556 DOI: 10.1016/j.jaci.2021.01.009 |
0.394 |
|
| 2020 |
Gachet C, Hechler B. Platelet Purinergic Receptors in Thrombosis and Inflammation. Hamostaseologie. 40: 145-152. PMID 32464678 DOI: 10.1055/A-1113-0711 |
0.723 |
|
| 2020 |
Do Sacramento V, Mallo L, Freund M, Eckly A, Hechler B, Mangin P, Lanza F, Gachet C, Strassel C. Functional properties of human platelets derived in vitro from CD34 cells. Scientific Reports. 10: 914. PMID 31969609 DOI: 10.1038/S41598-020-57754-9 |
0.663 |
|
| 2019 |
Hechler B, Dupuis A, Mangin PH, Gachet C. Platelet preparation for function testing in the laboratory and clinic: Historical and practical aspects. Research and Practice in Thrombosis and Haemostasis. 3: 615-625. PMID 31624781 DOI: 10.1002/rth2.12240 |
0.597 |
|
| 2019 |
Aguilar A, Weber J, Boscher J, Freund M, Ziessel C, Eckly A, Magnenat S, Bourdon C, Hechler B, Mangin PH, Gachet C, Lanza F, Léon C. Combined deficiency of RAB32 and RAB38 in the mouse mimics Hermansky-Pudlak syndrome and critically impairs thrombosis. Blood Advances. 3: 2368-2380. PMID 31399401 DOI: 10.1182/Bloodadvances.2019031286 |
0.59 |
|
| 2019 |
El Mdawar MB, Maître B, Magnenat S, Gachet C, Hechler B, de la Salle H. The ATP-gated P2X ion channel contributes to the severity of antibody-mediated Transfusion-Related Acute Lung Injury in mice. Scientific Reports. 9: 5159. PMID 30914724 DOI: 10.1038/S41598-019-41742-9 |
0.522 |
|
| 2018 |
Laurent PA, Hechler B, Solinhac R, Ragab A, Cabou C, Anquetil T, Severin S, Denis CV, Mangin PH, Vanhaesebroeck B, Payrastre B, Gratacap MP. Impact of PI3Kα (Phosphoinositide 3-Kinase Alpha) Inhibition on Hemostasis and Thrombosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 38: 2041-2053. PMID 30354258 DOI: 10.1161/Atvbaha.118.311410 |
0.445 |
|
| 2018 |
Beutier H, Hechler B, Godon O, Wang Y, Gillis CM, de Chaisemartin L, Gouel-Chéron A, Magnenat S, Macdonald LE, Murphy AJ, Chollet-Martin S, Longrois D, Gachet C, Bruhns P, et al. Platelets expressing IgG receptor FcγRIIA/CD32A determine the severity of experimental anaphylaxis. Science Immunology. 3. PMID 29654057 DOI: 10.1126/Sciimmunol.Aan5997 |
0.701 |
|
| 2018 |
Vermehren P, Trotman-Lucas M, Hechler B, Gachet C, Evans R, Gibson C, Fern R. Cooperation between NMDA-Type Glutamate and P2 Receptors for Neuroprotection during Stroke: Combining Astrocyte and Neuronal Protection Neuroglia. 1: 30-47. DOI: 10.3390/NEUROGLIA1010005 |
0.445 |
|
| 2017 |
Hechler B, Ravanat C, Gachet C. Amotosalen/UVA pathogen inactivation technology reduces platelet activability, induces apoptosis and accelerates clearance. Haematologica. 102: e502-e503. PMID 29192131 DOI: 10.3324/Haematol.2017.180539 |
0.633 |
|
| 2017 |
Ayme-Dietrich E, Lawson R, Côté F, de Tapia C, Da Silva S, Ebel C, Hechler B, Gachet C, Guyonnet J, Rouillard H, Stoltz J, Quentin E, Banas S, Daubeuf F, Frossard N, et al. Serotonergic 5-HT2B receptors in mitral valvulopathy: bone marrow mobilization of endothelial progenitors. British Journal of Pharmacology. PMID 28806488 DOI: 10.1111/Bph.13981 |
0.465 |
|
| 2017 |
Alberio L, Ravanat C, Hechler B, Mangin PH, Lanza F, Gachet C. Delayed-onset of procoagulant signalling revealed by kinetic analysis of COAT platelet formation. Thrombosis and Haemostasis. PMID 28382366 DOI: 10.1160/Th16-09-0711 |
0.617 |
|
| 2016 |
Ohlmann P, Hechler B, Chafey P, Ravanat C, Isola H, Wiesel ML, Cazenave JP, Gachet C. Hemostatic properties and protein expression profile of therapeutic apheresis plasma treated with amotosalen and ultraviolet A for pathogen inactivation. Transfusion. 56: 2239-47. PMID 27250038 DOI: 10.1111/Trf.13670 |
0.501 |
|
| 2016 |
Hechler B, Maître B, Magnenat S, Heim V, El Mdawar MB, Gachet C, de la Salle H. Platelets are dispensable for antibody-mediated transfusion-related acute lung injury in the mouse. Journal of Thrombosis and Haemostasis : Jth. 14: 1255-67. PMID 27063192 DOI: 10.1111/Jth.13335 |
0.621 |
|
| 2016 |
Hechler B, Zimmermann C, Rabouel Y, Magnenat S, Burban M, Boisramé-Helms J, Meziani F, Gachet C. A Potential Protective Role of Platelets during Septic Shock Does Not Depend on Their Purinergic Receptors Blood. 128: 2537-2537. DOI: 10.1182/Blood.V128.22.2537.2537 |
0.633 |
|
| 2016 |
Lhermusier T, Severin S, Van Rothem J, Garcia C, Bertrand-Michel J, Le Faouder P, Hechler B, Broccardo C, Couvert P, Chimini G, Sié P, Payrastre B. ATP-binding cassette transporter 1 (ABCA1) deficiency decreases platelet reactivity and reduces thromboxane A2 production independently of hematopoietic ABCA1 Journal of Thrombosis and Haemostasis. 14: 585-595. DOI: 10.1111/Jth.13247 |
0.538 |
|
| 2015 |
Hechler B, Gachet C. Purinergic Receptors in Thrombosis and Inflammation. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 2307-15. PMID 26359511 DOI: 10.1161/Atvbaha.115.303395 |
0.646 |
|
| 2015 |
Ciciliano JC, Sakurai Y, Myers DR, Fay ME, Hechler B, Meeks S, Li R, Dixon JB, Lyon LA, Gachet C, Lam WA. Resolving the multifaceted mechanisms of the ferric chloride thrombosis model using an interdisciplinary microfluidic approach. Blood. PMID 25931587 DOI: 10.1182/Blood-2015-02-628594 |
0.578 |
|
| 2015 |
Maître B, Magnenat S, Heim V, Ravanat C, Evans RJ, de la Salle H, Gachet C, Hechler B. The P2X1 receptor is required for neutrophil extravasation during lipopolysaccharide-induced lethal endotoxemia in mice. Journal of Immunology (Baltimore, Md. : 1950). 194: 739-49. PMID 25480563 DOI: 10.4049/Jimmunol.1401786 |
0.586 |
|
| 2015 |
Laurent PA, Séverin S, Hechler B, Vanhaesebroeck B, Payrastre B, Gratacap MP. Platelet PI3Kβ and GSK3 regulate thrombus stability at a high shear rate. Blood. 125: 881-8. PMID 25398937 DOI: 10.1182/Blood-2014-07-588335 |
0.502 |
|
| 2015 |
Alame G, Mangin PH, Freund M, Riehl N, Magnenat S, Petitou M, Hechler B, Gachet C. EP217609, a neutralisable dual-action FIIa/FXa anticoagulant, with antithrombotic effects in arterial thrombosis. Thrombosis and Haemostasis. 113: 385-95. PMID 25374268 DOI: 10.1160/Th14-05-0399 |
0.525 |
|
| 2015 |
Laurent P, Severin S, Hechler B, Vanhaesebroeck B, Payrastre B, Gratacap M. 0448 : Essential role of platelet PI3Kβ and GSK3 in thrombus stability at high shear rate Archives of Cardiovascular Diseases Supplements. 7: 131-132. DOI: 10.1016/S1878-6480(15)30006-9 |
0.323 |
|
| 2015 |
Hechler B, Ravanat C, Ohlmann P, Eckly A, Leduc M, Guillonneau F, Isola H, Gachet C. L’inactivation des pathogènes par la technologie Intercept® préserve l’ultrastructure et les propriétés biochimiques des plaquettes au cours de leur conservation en vue de transfusion Transfusion Clinique Et Biologique. 22: 222. DOI: 10.1016/J.Tracli.2015.06.026 |
0.431 |
|
| 2013 |
Schaff M, Tang C, Maurer E, Bourdon C, Receveur N, Eckly A, Hechler B, Arnold C, De Arcangelis A, Nieswandt B, Denis CV, Lefebvre O, Georges-Labouesse E, Gachet C, Lanza F, et al. Integrin α6β1 is the main receptor for vascular laminins and plays a role in platelet adhesion, activation, and arterial thrombosis Circulation. 128: 541-552. PMID 23797810 DOI: 10.1161/Circulationaha.112.000799 |
0.627 |
|
| 2013 |
Maurer E, Tang C, Schaff M, Bourdon C, Receveur N, Ravanat C, Eckly A, Hechler B, Gachet C, Lanza F, Mangin PH. Targeting platelet GPIbβ reduces platelet adhesion, GPIb signaling and thrombin generation and prevents arterial thrombosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 1221-9. PMID 23559635 DOI: 10.1161/Atvbaha.112.301013 |
0.661 |
|
| 2013 |
Hechler B, Ohlmann P, Chafey P, Ravanat C, Eckly A, Maurer E, Mangin P, Isola H, Cazenave JP, Gachet C. Preserved functional and biochemical characteristics of platelet components prepared with amotosalen and ultraviolet A for pathogen inactivation. Transfusion. 53: 1187-200. PMID 23067365 DOI: 10.1111/J.1537-2995.2012.03923.X |
0.595 |
|
| 2013 |
Zahid M, Mangin P, Loyau S, Hechler B, Billiald P, Gachet C, Jandrot-Perrus M. The future of glycoprotein VI as an antithrombotic target. Journal of Thrombosis and Haemostasis : Jth. 10: 2418-27. PMID 23020554 DOI: 10.1111/Jth.12009 |
0.531 |
|
| 2013 |
Maitre B, Leguay C, De La Salle H, Hechler B, Gachet C. NF449, un antagoniste du récepteur P2X1, inhibe le développement du TRALI dans un modèle murin Transfusion Clinique Et Biologique. 20: 289. DOI: 10.1016/J.Tracli.2013.04.016 |
0.449 |
|
| 2013 |
Hechler B, Ohlmann P, Chafey P, Ravanat C, Eckly A, Maurer E, Mangin P, Isola H, Cazenave J, Gachet C. L’inactivation des pathogènes par la technologie Intercept® préserve les propriétés fonctionnelles et biochimiques des plaquettes au cours de leur conservation en vue de transfusion Transfusion Clinique Et Biologique. 20: 334. DOI: 10.1016/J.Tracli.2013.03.152 |
0.427 |
|
| 2013 |
Gachet C, Hechler B. The P2Y receptors and thrombosis Wiley Interdisciplinary Reviews: Membrane Transport and Signaling. 2: 241-253. DOI: 10.1002/WMTS.97 |
0.555 |
|
| 2012 |
Mangin PH, Tang C, Bourdon C, Loyau S, Freund M, Hechler B, Gachet C, Jandrot-Perrus M. A humanized glycoprotein VI (GPVI) mouse model to assess the antithrombotic efficacies of anti-GPVI agents. The Journal of Pharmacology and Experimental Therapeutics. 341: 156-63. PMID 22238212 DOI: 10.1124/Jpet.111.189050 |
0.6 |
|
| 2012 |
Gachet C, Hechler B, Léon C, Vial C, Ohlmann P, Cazenave JP. Purinergic receptors on blood platelets. Platelets. 7: 261-7. PMID 21043660 DOI: 10.3109/09537109609023587 |
0.82 |
|
| 2012 |
Gachet C, Léon C, Hechler B. Corrigendum to “The platelet P2 receptors in arterial thrombosis” [Blood Cells Mol. Dis. 36 (2006) 223–227] Blood Cells, Molecules, and Diseases. 49: 120. DOI: 10.1016/J.Bcmd.2012.05.013 |
0.646 |
|
| 2011 |
Hechler B, Gachet C. P2 receptors and platelet function. Purinergic Signalling. 7: 293-303. PMID 21792575 DOI: 10.1007/S11302-011-9247-6 |
0.728 |
|
| 2011 |
Zerr M, Hechler B, Freund M, Magnenat S, Lanois I, Cazenave JP, Léon C, Gachet C. Major contribution of the P2Y₁receptor in purinergic regulation of TNFα-induced vascular inflammation. Circulation. 123: 2404-13. PMID 21576651 DOI: 10.1161/Circulationaha.110.002139 |
0.543 |
|
| 2011 |
Hechler B, Freund M, Alame G, Leguay C, Gaertner S, Cazenave JP, Petitou M, Gachet C. The antithrombotic activity of EP224283, a neutralizable dual factor Xa inhibitor/glycoprotein IIbIIIa antagonist, exceeds that of the coadministered parent compounds. The Journal of Pharmacology and Experimental Therapeutics. 338: 412-20. PMID 21527535 DOI: 10.1124/Jpet.111.181321 |
0.563 |
|
| 2011 |
Hechler B, Gachet C. Comparison of two murine models of thrombosis induced by atherosclerotic plaque injury. Thrombosis and Haemostasis. 105: S3-12. PMID 21479341 DOI: 10.1160/Ths10-11-0730 |
0.573 |
|
| 2011 |
Eckly A, Hechler B, Freund M, Zerr M, Cazenave JP, Lanza F, Mangin PH, Gachet C. Mechanisms underlying FeCl3-induced arterial thrombosis. Journal of Thrombosis and Haemostasis : Jth. 9: 779-89. PMID 21261806 DOI: 10.1111/J.1538-7836.2011.04218.X |
0.486 |
|
| 2010 |
de Castro S, Maruoka H, Hong K, Kilbey SM, Costanzi S, Hechler B, Brown GG, Gachet C, Harden TK, Jacobson KA. Functionalized congeners of P2Y1 receptor antagonists: 2-alkynyl (N)-methanocarba 2'-deoxyadenosine 3',5'-bisphosphate analogues and conjugation to a polyamidoamine (PAMAM) dendrimer carrier. Bioconjugate Chemistry. 21: 1190-205. PMID 20565071 DOI: 10.1021/Bc900569U |
0.596 |
|
| 2010 |
Ravanat C, Strassel C, Hechler B, Schuhler S, Chicanne G, Payrastre B, Gachet C, Lanza F. A central role of GPIb-IX in the procoagulant function of platelets that is independent of the 45-kDa GPIbalpha N-terminal extracellular domain. Blood. 116: 1157-64. PMID 20457869 DOI: 10.1182/Blood-2010-01-266080 |
0.653 |
|
| 2010 |
Hechler B, Nonne C, Eckly A, Magnenat S, Rinckel JY, Denis CV, Freund M, Cazenave JP, Lanza F, Gachet C. Arterial thrombosis: relevance of a model with two levels of severity assessed by histologic, ultrastructural and functional characterization. Journal of Thrombosis and Haemostasis : Jth. 8: 173-84. PMID 19874458 DOI: 10.1111/J.1538-7836.2009.03666.X |
0.559 |
|
| 2009 |
Kim Y, Hechler B, Gao ZG, Gachet C, Jacobson KA. PEGylated dendritic unimolecular micelles as versatile carriers for ligands of G protein-coupled receptors. Bioconjugate Chemistry. 20: 1888-98. PMID 19785401 DOI: 10.1021/Bc9001689 |
0.571 |
|
| 2009 |
Strassel C, Hechler B, Bull A, Gachet C, Lanza F. Studies of mice lacking the GPIb-V-IX complex question the role of this receptor in atherosclerosis. Journal of Thrombosis and Haemostasis : Jth. 7: 1935-8. PMID 19740100 DOI: 10.1111/J.1538-7836.2009.03608.X |
0.615 |
|
| 2009 |
Kim Y, Klutz AM, Hechler B, Gao ZG, Gachet C, Jacobson KA. Application of the functionalized congener approach to dendrimer-based signaling agents acting through A(2A) adenosine receptors. Purinergic Signalling. 5: 39-50. PMID 18600474 DOI: 10.1007/S11302-008-9113-3 |
0.575 |
|
| 2008 |
Hechler B, Freund M, Ravanat C, Magnenat S, Cazenave JP, Gachet C. Reduced atherosclerotic lesions in P2Y1/apolipoprotein E double-knockout mice: the contribution of non-hematopoietic-derived P2Y1 receptors. Circulation. 118: 754-63. PMID 18663083 DOI: 10.1161/Circulationaha.108.788927 |
0.565 |
|
| 2008 |
Ohlmann P, Hechler B, Ravanat C, Loyau S, Herrenschmidt N, Wanert F, Jandrot-Perrus M, Gachet C. Ex vivo inhibition of thrombus formation by an anti-glycoprotein VI Fab fragment in non-human primates without modification of glycoprotein VI expression. Journal of Thrombosis and Haemostasis : Jth. 6: 1003-11. PMID 18419749 DOI: 10.1111/J.1538-7836.2008.02976.X |
0.521 |
|
| 2008 |
Gao ZG, Hechler B, Besada P, Gachet C, Jacobson KA. Caged agonist of P2Y1 and P2Y12 receptors for light-directed facilitation of platelet aggregation. Biochemical Pharmacology. 75: 1341-7. PMID 18199424 DOI: 10.1016/J.Bcp.2007.10.037 |
0.678 |
|
| 2008 |
Kim Y, Hechler B, Klutz AM, Gachet C, Jacobson KA. Toward multivalent signaling across G protein-coupled receptors from poly(amidoamine) dendrimers. Bioconjugate Chemistry. 19: 406-11. PMID 18176997 DOI: 10.1021/Bc700327U |
0.641 |
|
| 2007 |
Lantz N, Hechler B, Ravanat C, Cazenave JP, Gachet C. A high concentration of ADP induces weak platelet granule secretion independently of aggregation and thromboxane A2 production. Thrombosis and Haemostasis. 98: 1145-7. PMID 18000625 DOI: 10.1160/Th07-06-0392 |
0.765 |
|
| 2007 |
Nonne C, Hechler B, Cazenave JP, Gachet C, Lanza F. Reassessment of in vivo thrombus formation in glycoprotein V deficient mice backcrossed on a C57Bl/6 strain. Journal of Thrombosis and Haemostasis : Jth. 6: 210-2. PMID 17988230 DOI: 10.1111/J.1538-7836.2007.02825.X |
0.481 |
|
| 2007 |
Léon C, Eckly A, Hechler B, Aleil B, Freund M, Ravanat C, Jourdain M, Nonne C, Weber J, Tiedt R, Gratacap MP, Severin S, Cazenave JP, Lanza F, Skoda R, et al. Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion. Blood. 110: 3183-91. PMID 17664350 DOI: 10.1182/Blood-2007-03-080184 |
0.68 |
|
| 2007 |
Wurtz V, Hechler B, Ohlmann P, Isola H, Schaeffer-Reiss C, Cazenave JP, Van Dorsselaer A, Gachet C. Identification of platelet factor 4 and beta-thromboglobulin by profiling and liquid chromatography tandem mass spectrometry of supernatant peptides in stored apheresis and buffy-coat platelet concentrates. Transfusion. 47: 1099-101. PMID 17524104 DOI: 10.1111/J.1537-2995.2007.01260.X |
0.565 |
|
| 2007 |
Hechler B, Freund M, Ravanat C, Magnenat S, Cazenave J, Gachet C. REDUCED ATHEROSCLEROTIC LESIONS IN P2Y1/APOE DOUBLE KNOCKOUT MICE Journal of Thrombosis and Haemostasis. 5: O-S-082-O-S-082. DOI: 10.1111/J.1538-7836.2007.Tb00085.X |
0.48 |
|
| 2006 |
Gachet C, Hechler B, Nonne C, Cazenave JP, Lanza F, Aleil B. [Atherothrombosis: transposition of the models to the clinic and reciprocally]. Therapie. 61: 389-94. PMID 17243267 DOI: 10.2515/Therapie:2006067 |
0.515 |
|
| 2006 |
Gachet C, Léon C, Hechler B. The platelet P2 receptors in arterial thrombosis. Blood Cells, Molecules & Diseases. 36: 223-7. PMID 16466948 DOI: 10.1016/J.Bcmd.2005.12.024 |
0.667 |
|
| 2006 |
Hechler B, Nonne C, Roh EJ, Cattaneo M, Cazenave JP, Lanza F, Jacobson KA, Gachet C. MRS2500 [2-iodo-N6-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate], a potent, selective, and stable antagonist of the platelet P2Y1 receptor with strong antithrombotic activity in mice. The Journal of Pharmacology and Experimental Therapeutics. 316: 556-63. PMID 16236815 DOI: 10.1124/Jpet.105.094037 |
0.702 |
|
| 2005 |
Soulet C, Hechler B, Gratacap MP, Plantavid M, Offermanns S, Gachet C, Payrastre B. A differential role of the platelet ADP receptors P2Y1 and P2Y12 in Rac activation. Journal of Thrombosis and Haemostasis : Jth. 3: 2296-306. PMID 16194206 DOI: 10.1111/J.1538-7836.2005.01588.X |
0.651 |
|
| 2005 |
Gachet C, Hechler B. The platelet P2 receptors in thrombosis. Seminars in Thrombosis and Hemostasis. 31: 162-7. PMID 15852219 DOI: 10.1055/S-2005-869521 |
0.664 |
|
| 2005 |
Hechler B, Cattaneo M, Gachet C. The P2 receptors in platelet function. Seminars in Thrombosis and Hemostasis. 31: 150-61. PMID 15852218 DOI: 10.1055/S-2005-869520 |
0.728 |
|
| 2005 |
Hechler B, Magnenat S, Zighetti ML, Kassack MU, Ullmann H, Cazenave JP, Evans R, Cattaneo M, Gachet C. Inhibition of platelet functions and thrombosis through selective or nonselective inhibition of the platelet P2 receptors with increasing doses of NF449 [4,4',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis-(carbonylimino)))tetrakis-benzene-1,3-disulfonic acid octasodium salt]. The Journal of Pharmacology and Experimental Therapeutics. 314: 232-43. PMID 15792995 DOI: 10.1124/Jpet.105.084673 |
0.689 |
|
| 2005 |
Nonne C, Lenain N, Hechler B, Mangin P, Cazenave JP, Gachet C, Lanza F. Importance of platelet phospholipase Cgamma2 signaling in arterial thrombosis as a function of lesion severity. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 1293-8. PMID 15774906 DOI: 10.1161/01.Atv.0000163184.02484.69 |
0.663 |
|
| 2005 |
Baurand A, Eckly A, Hechler B, Kauffenstein G, Galzi JL, Cazenave JP, Léon C, Gachet C. Differential regulation and relocalization of the platelet P2Y receptors after activation: a way to avoid loss of hemostatic properties? Molecular Pharmacology. 67: 721-33. PMID 15602005 DOI: 10.1124/Mol.104.004846 |
0.809 |
|
| 2005 |
Kauffenstein G, Hechler B, Cazenave JP, Gachet C. Adenine triphosphate nucleotides are antagonists at the P2Y receptor. Journal of Thrombosis and Haemostasis : Jth. 2: 1980-8. PMID 15550030 DOI: 10.1111/J.1538-7836.2004.00926.X |
0.796 |
|
| 2004 |
Ohlmann P, Hechler B, Cazenave JP, Gachet C. Measurement and manipulation of [Ca2+]i in suspensions of platelets and cell cultures. Methods in Molecular Biology (Clifton, N.J.). 273: 229-50. PMID 15308805 DOI: 10.1385/1-59259-783-1:229 |
0.553 |
|
| 2004 |
Cazenave JP, Ohlmann P, Cassel D, Eckly A, Hechler B, Gachet C. Preparation of washed platelet suspensions from human and rodent blood. Methods in Molecular Biology (Clifton, N.J.). 272: 13-28. PMID 15226531 DOI: 10.1385/1-59259-782-3:013 |
0.638 |
|
| 2003 |
Hechler B, Lenain N, Marchese P, Vial C, Heim V, Freund M, Cazenave JP, Cattaneo M, Ruggeri ZM, Evans R, Gachet C. A role of the fast ATP-gated P2X1 cation channel in thrombosis of small arteries in vivo. The Journal of Experimental Medicine. 198: 661-7. PMID 12913094 DOI: 10.1084/Jem.20030144 |
0.808 |
|
| 2003 |
Hechler B, Zhang Y, Eckly A, Cazenave JP, Gachet C, Ravid K. Lineage-specific overexpression of the P2Y 1 receptor induces platelet hyper-reactivity in transgenic mice Journal of Thrombosis and Haemostasis. 1: 155-163. PMID 12871553 DOI: 10.1046/j.1538-7836.2003.00003.x |
0.704 |
|
| 2003 |
Hechler B, Lenain N, Marchese P, Vial C, Heim V, Freund M, Cazenave J, Cattaneo M, Ruggeri Z, Evans R, Gachet C. A key role of the fast ATP-gated P2X1cation channel in the thrombosis of small arteriesin vivo Journal of Thrombosis and Haemostasis. 1: OC209-OC209. DOI: 10.1111/J.1538-7836.2003.Tb04596.X |
0.697 |
|
| 2002 |
Boeynaems J, Communi D, Suarez Gonzalez N, Hechler B, Léon C, Gachet C. Les récepteurs P2Y des nucléotides extracellulaires : du clonage à la physiologie MéDecine/Sciences. 18: 965-973. DOI: 10.1051/Medsci/20021810965 |
0.438 |
|
| 2001 |
Hechler B, Toselli P, Ravanat C, Gachet C, Ravid K. Mpl ligand increases P2Y1 receptor gene expression in megakaryocytes with no concomitant change in platelet response to ADP Molecular Pharmacology. 60: 1112-1120. PMID 11641440 DOI: 10.1124/Mol.60.5.1112 |
0.603 |
|
| 2001 |
Eckly A, Gendrault J, Hechler B, Cazenave J, Gachet C. Differential Involvement of the P2Y1 and P2YT Receptors in the Morphological Changes of Platelet Aggregation Thrombosis and Haemostasis. 85: 694-701. DOI: 10.1055/S-0037-1615655 |
0.713 |
|
| 2000 |
Léon C, Hechler B, Freund M, Eckly A, Vial C, Ohlmann P, Dierich A, LeMeur M, Cazenave JP, Gachet C. Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y(1) receptor-null mice. The Journal of Clinical Investigation. 104: 1731-7. PMID 10606627 DOI: 10.1172/Jci8399 |
0.83 |
|
| 2000 |
Baurand A, Eckly A, Bari N, Léon C, Hechler B, Cazenave J, Gachet C. Desensitization of the Platelet Aggregation Response to ADP: Differential Down-regulation of the P2Y1 and P2cyc Receptors Thrombosis and Haemostasis. 84: 484-491. DOI: 10.1055/S-0037-1614049 |
0.714 |
|
| 1999 |
Vigne P, Hechler B, Gachet C, Breittmayer JP, Frelin C. Benzoyl ATP is an antagonist of rat and human P2Y1 receptors and of platelet aggregation. Biochemical and Biophysical Research Communications. 256: 94-7. PMID 10066429 DOI: 10.1006/Bbrc.1999.9558 |
0.665 |
|
| 1999 |
Hechler B, Eckly A, Ohlmann P, Cazenave JP, Gachet C. The P2Y1 receptor, necessary but not sufficient to support full ADP-induced platelet aggregation, is not the target of the drug clopidogrel. British Journal of Haematology. 103: 858-66. PMID 9858246 DOI: 10.1046/J.1365-2141.1998.01056.X |
0.708 |
|
| 1999 |
Trumel C, Payrastre B, Plantavid M, Hechler B, Viala C, Presek P, Martinson EA, Cazenave J, Chap H, Gachet C. A Key Role of Adenosine Diphosphate in the Irreversible Platelet Aggregation Induced by the PAR1-Activating Peptide Through the Late Activation of Phosphoinositide 3-Kinase Blood. 94: 4156-4165. DOI: 10.1182/Blood.V94.12.4156.424K29_4156_4165 |
0.674 |
|
| 1999 |
Léon C, Vial C, Ohlmann P, Hechler B, Cazenave J, Lecchi A, Cattaneo M, Gachet C. The P2Y1 Receptor Is Normal in a Patient Presenting a Severe Deficiency of ADP-induced Platelet Aggregation Thrombosis and Haemostasis. 81: 775-781. DOI: 10.1055/S-0037-1614570 |
0.825 |
|
| 1998 |
Hechler B, Léon C, Vial C, Vigne P, Frelin C, Cazenave J, Gachet C. The P2Y1 Receptor Is Necessary for Adenosine 5′-Diphosphate–Induced Platelet Aggregation Blood. 92: 152-159. DOI: 10.1182/Blood.V92.1.152.413K27_152_159 |
0.828 |
|
| 1998 |
Hechler B, Vigne P, Léon C, Breittmayer J, Gachet C, Frelin C. ATP Derivatives Are Antagonists of the P2Y1 Receptor: Similarities to the Platelet ADP Receptor Molecular Pharmacology. 53: 727-733. DOI: 10.1124/Mol.53.4.727 |
0.627 |
|
| 1997 |
Léon C, Hechler B, Vial C, Leray C, Cazenave JP, Gachet C. The P2Y1 receptor is an ADP receptor antagonized by ATP and expressed in platelets and megakaryoblastic cells. Febs Letters. 403: 26-30. PMID 9038354 DOI: 10.1016/S0014-5793(97)00022-7 |
0.81 |
|
| 1996 |
Gachet C, Cattaneo M, Ohlmann P, Hechler B, Lecchi A, Chevalier J, Cassel D, Mannucci PM, Cazenave JP. Purinoceptors on blood platelets: further pharmacological and clinical evidence to suggest the presence of two ADP receptors. British Journal of Haematology. 91: 434-44. PMID 8547091 DOI: 10.1111/J.1365-2141.1995.Tb05319.X |
0.695 |
|
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