Owen P. Hamill, PhD - Publications

Affiliations: 
University of Texas Medical Branch, Galveston, TX 
Area:
Mechanosensitive ion channels

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Nikolaev YA, Dosen PJ, Laver DR, Van Helden DF, Hamill OP. Biophysical Factors that Promote Mechanically-Induced Action Potentials in Neocortical and Hippocampal Pyramidal Neurons Biophysical Journal. 110: 349a. DOI: 10.1016/J.Bpj.2015.11.1877  0.45
2015 Nikolaev YA, Dosen PJ, Laver DR, van Helden DF, Hamill OP. Single mechanically-gated cation channel currents can trigger action potentials in neocortical and hippocampal pyramidal neurons. Brain Research. 1608: 1-13. PMID 25765154 DOI: 10.1016/J.Brainres.2015.02.051  0.45
2013 Soria B, Navas S, Hmadcha A, Hamill OP. Single mechanosensitive and Ca²⁺-sensitive channel currents recorded from mouse and human embryonic stem cells. The Journal of Membrane Biology. 246: 215-30. PMID 23188062 DOI: 10.1007/S00232-012-9523-6  0.46
2012 Maroto R, Kurosky A, Hamill OP. Mechanosensitive Ca(2+) permeant cation channels in human prostate tumor cells. Channels (Austin, Tex.). 6: 290-307. PMID 22874798 DOI: 10.4161/Chan.21063  0.368
2008 Gottlieb P, Folgering J, Maroto R, Raso A, Wood TG, Kurosky A, Bowman C, Bichet D, Patel A, Sachs F, Martinac B, Hamill OP, Honoré E. Revisiting TRPC1 and TRPC6 mechanosensitivity. Pflã¼Gers Archiv : European Journal of Physiology. 455: 1097-103. PMID 17957383 DOI: 10.1007/S00424-007-0359-3  0.431
2007 Hamill OP, Maroto R. TRPCs as MS Channels. Current Topics in Membranes. 59: 191-231. PMID 25168139 DOI: 10.1016/S1063-5823(06)59009-X  0.412
2007 Hamill OP. Foreword. Mechanosensitive Ion Channels, Part A Current Topics in Membranes. 58: XV-XVI. DOI: 10.1016/S1063-5823(06)58018-4  0.465
2006 Hamill OP. Twenty odd years of stretch-sensitive channels. Pflã¼Gers Archiv : European Journal of Physiology. 453: 333-51. PMID 17021800 DOI: 10.1007/S00424-006-0131-0  0.438
2005 Maroto R, Raso A, Wood TG, Kurosky A, Martinac B, Hamill OP. TRPC1 forms the stretch-activated cation channel in vertebrate cells. Nature Cell Biology. 7: 179-85. PMID 15665854 DOI: 10.1038/Ncb1218  0.44
2002 Martinac B, Hamill OP. Gramicidin A channels switch between stretch activation and stretch inactivation depending on bilayer thickness. Proceedings of the National Academy of Sciences of the United States of America. 99: 4308-12. PMID 11904391 DOI: 10.1073/Pnas.072632899  0.452
2001 Hamill OP, Martinac B. Molecular basis of mechanotransduction in living cells. Physiological Reviews. 81: 685-740. PMID 11274342 DOI: 10.1152/Physrev.2001.81.2.685  0.406
2001 Hamill OP. Targeting specific Na+ channel subunits: The key to neuropathic pain? Neuroreport. 12: A11. DOI: 10.1097/00001756-200103050-00001  0.336
2000 Sachs F, Morris CE, Hamill O. Does a stretch-inactivated cation channel integrate osmotic and peptidergic signals? Nature Neuroscience. 3: 847-8. PMID 10966605 DOI: 10.1038/78730  0.388
2000 Zhang Y, Gao F, Popov VL, Wen JW, Hamill OP. Mechanically gated channel activity in cytoskeleton-deficient plasma membrane blebs and vesicles from Xenopus oocytes. The Journal of Physiology. 523: 117-30. PMID 10673548 DOI: 10.1111/J.1469-7793.2000.T01-1-00117.X  0.471
2000 Zhang Y, Hamill OP. On the discrepancy between whole-cell and membrane patch mechanosensitivity in Xenopus oocytes. The Journal of Physiology. 523: 101-15. PMID 10673547 DOI: 10.1111/J.1469-7793.2000.00101.X  0.432
2000 Zhang Y, Hamill OP. Calcium-, voltage- and osmotic stress-sensitive currents in Xenopus oocytes and their relationship to single mechanically gated channels. The Journal of Physiology. 523: 83-99. PMID 10673546 DOI: 10.1111/J.1469-7793.2000.T01-2-00083.X  0.499
1999 McBride DW, Hamill OP. Simplified fast pressure-clamp technique for studying mechanically gated channels. Methods in Enzymology. 294: 482-9. PMID 9916244 DOI: 10.1016/S0076-6879(99)94028-4  0.323
1998 Wilkinson NC, Gao F, Hamill OP. Effects of mechano-gated cation channel blockers on Xenopus oocyte growth and development. The Journal of Membrane Biology. 165: 161-74. PMID 9745004 DOI: 10.1007/S002329900430  0.444
1998 Zhang Y, McBride DW, Hamill OP. The ion selectivity of a membrane conductance inactivated by extracellular calcium in Xenopus oocytes. The Journal of Physiology. 508: 763-76. PMID 9518731 DOI: 10.1111/J.1469-7793.1998.763Bp.X  0.402
1998 Wu G, McBride DW, Hamill OP. Mg2+ block and inward rectification of mechanosensitive channels in Xenopus oocytes. Pflã¼Gers Archiv : European Journal of Physiology. 435: 572-4. PMID 9446706 DOI: 10.1007/S004240050554  0.419
1997 Hamill OP. How many transmitter binding steps are involved in opening fast receptor-gated channels? Neuroreport. 8: iv. PMID 9480006  0.301
1997 Hamill OP, McBride DW. Induced membrane hypo/hyper-mechanosensitivity: a limitation of patch-clamp recording. Annual Review of Physiology. 59: 621-31. PMID 9074780 DOI: 10.1146/Annurev.Physiol.59.1.621  0.443
1997 Hamill OP, McBride DW. Mechanogated channels in Xenopus oocytes: different gating modes enable a channel to switch from a phasic to a tonic mechanotransducer. The Biological Bulletin. 192: 121-2. PMID 9057280 DOI: 10.2307/1542583  0.31
1996 Hamill OP, McBride DW. The pharmacology of mechanogated membrane ion channels. Pharmacological Reviews. 48: 231-52. PMID 8804105  0.351
1995 Hamill OP, McBride Jnr DW. Mechanoreceptive membrane channels Am.Sci.. 83: 30-37.  0.355
1994 Liu E, Hamill OP, Salpeter MM. Mouse muscle epsilon- and gamma-containing acetylcholine receptors expressed in Xenopus laevis oocytes do not differ in their degradation half-lives. Neuroscience Letters. 174: 77-80. PMID 7970160 DOI: 10.1016/0304-3940(94)90123-6  0.307
1994 Hamill OP, McBride DW. The cloning of a mechano-gated membrane ion channel. Trends in Neurosciences. 17: 439-43. PMID 7531881 DOI: 10.1016/0166-2236(94)90125-2  0.446
1993 McBride DW, Hamill OP. Pressure-clamp technique for measurement of the relaxation kinetics of mechanosensitive channels. Trends in Neurosciences. 16: 341-5. PMID 7694402 DOI: 10.1016/0166-2236(93)90089-5  0.399
1993 Lane JW, McBride DW, Hamill OP. Ionic effects on amiloride block of the mechanosensitive channel in Xenopus oocytes. British Journal of Pharmacology. 108: 116-9. PMID 7679024 DOI: 10.1111/J.1476-5381.1993.Tb13449.X  0.42
1992 Golino MD, Hamill OP. Subunit requirements for Torpedo AChR channel expression: a specific role for the delta-subunit in voltage-dependent gating. The Journal of Membrane Biology. 129: 297-309. PMID 1433281 DOI: 10.1007/Bf00232911  0.363
1992 Hamill OP, Lane JW, McBride DW. Amiloride: a molecular probe for mechanosensitive channels. Trends in Pharmacological Sciences. 13: 373-6. PMID 1384211 DOI: 10.1016/0165-6147(92)90115-M  0.349
1992 Lane JW, McBride DW, Hamill OP. Structure-activity relations of amiloride and its analogues in blocking the mechanosensitive channel in Xenopus oocytes. British Journal of Pharmacology. 106: 283-6. PMID 1382778 DOI: 10.1111/J.1476-5381.1992.Tb14329.X  0.433
1992 Hamill OP, McBride DW. Rapid adaptation of single mechanosensitive channels in Xenopus oocytes. Proceedings of the National Academy of Sciences of the United States of America. 89: 7462-6. PMID 1380158 DOI: 10.1073/Pnas.89.16.7462  0.461
1992 McBride DW, Hamill OP. Pressure-clamp: a method for rapid step perturbation of mechanosensitive channels. Pflã¼Gers Archiv : European Journal of Physiology. 421: 606-12. PMID 1279516 DOI: 10.1007/Bf00375058  0.366
1991 Lane JW, McBride DW, Hamill OP. Amiloride block of the mechanosensitive cation channel in Xenopus oocytes. The Journal of Physiology. 441: 347-66. PMID 1816379 DOI: 10.1113/Jphysiol.1991.Sp018755  0.504
1991 Hamill OP, Huguenard JR, Prince DA. Patch-clamp studies of voltage-gated currents in identified neurons of the rat cerebral cortex. Cerebral Cortex (New York, N.Y. : 1991). 1: 48-61. PMID 1668364 DOI: 10.1093/Cercor/1.1.48  0.311
1989 Huguenard JR, Hamill OP, Prince DA. Sodium channels in dendrites of rat cortical pyramidal neurons. Proceedings of the National Academy of Sciences of the United States of America. 86: 2473-7. PMID 2538843 DOI: 10.1073/Pnas.86.7.2473  0.367
1988 Huguenard JR, Hamill OP, Prince DA. Developmental changes in Na+ conductances in rat neocortical neurons: appearance of a slowly inactivating component. Journal of Neurophysiology. 59: 778-95. PMID 2452862 DOI: 10.1152/Jn.1988.59.3.778  0.408
1987 Bormann J, Hamill OP, Sakmann B. Mechanism of anion permeation through channels gated by glycine and gamma-aminobutyric acid in mouse cultured spinal neurones. The Journal of Physiology. 385: 243-86. PMID 2443667 DOI: 10.1113/Jphysiol.1987.Sp016493  0.505
1983 Sakmann B, Bormann J, Hamill OP. Ion transport by single receptor channels. Cold Spring Harbor Symposia On Quantitative Biology. 48: 247-57. PMID 6327159 DOI: 10.1101/Sqb.1983.048.01.027  0.379
1983 Hamill OP, Bormann J, Sakmann B. Activation of multiple-conductance state chloride channels in spinal neurones by glycine and GABA. Nature. 305: 805-8. PMID 6314144 DOI: 10.1038/305805A0  0.398
1983 Gage PW, Hamill OP, Wachtel RE. Sites of action of procaine at the motor end-plate. The Journal of Physiology. 335: 123-37. PMID 6308216 DOI: 10.1113/Jphysiol.1983.Sp014524  0.569
1983 Sakmann B, Hamill OP, Bormann J. Patch-clamp measurements of elementary chloride currents activated by the putative inhibitory transmitter GABA and glycine in mammalian spinal neurons. Journal of Neural Transmission. Supplementum. 18: 83-95. PMID 6308154  0.356
1983 Sakmann B, Hamill OP, Bormann J. Patch−clamp measurements of elementary ionic currents activated by the putative inhibitory transmitters GABA and glycine in mammalian spinal neurones Journal of Neural Transmission-Supplement. 18: 83-95. DOI: 10.1007/978-3-7091-4408-4_8  0.458
1982 Adams DJ, Gage PW, Hamill OP. Inhibitory postsynaptic currents at Aplysia cholinergic synapses: effects of permeant anions and depressant drugs. Proceedings of the Royal Society of London. Series B, Biological Sciences. 214: 335-50. PMID 6127686 DOI: 10.1098/Rspb.1982.0015  0.661
1982 Hamill OP. Ca and volume sensitive K channels in frog red blood cells PflüGers Archiv European Journal of Physiology. 394: R30-R30. DOI: 10.1007/Bf02580695  0.334
1981 Hamill OP, Sakmann B. Multiple conductance states of single acetylcholine receptor channels in embryonic muscle cells. Nature. 294: 462-4. PMID 6273742 DOI: 10.1038/294462A0  0.443
1981 Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflã¼Gers Archiv : European Journal of Physiology. 391: 85-100. PMID 6270629 DOI: 10.1007/Bf00656997  0.45
1981 Gage PW, Hamill OP. Effects of anesthetics on ion channels in synapses. International Review of Physiology. 25: 1-45. PMID 6110640  0.567
1981 Hamill OP, Sakmann B. A cell-free method for recording single-channel currents from biological membranes The Journal of Physiology. 312: 41-42. DOI: 10.1113/Jphysiol.1981.Sp013646  0.462
1980 Gage PW, Hamill OP. Lifetime and conductance of acetylcholine-activated channels in normal and denervated toad sartorius muscle. The Journal of Physiology. 298: 525-38. PMID 6767026 DOI: 10.1113/Jphysiol.1980.Sp013099  0.652
1979 van Helden DF, Gage PW, Hamill OP. Conductance of end-plate channels is voltage dependent. Neuroscience Letters. 11: 227-32. PMID 460691 DOI: 10.1016/0304-3940(79)90133-2  0.654
1979 Gage PW, Hamill OP, Van Helden D. Dual effects of ether on end-plate currents. The Journal of Physiology. 287: 353-69. PMID 107308 DOI: 10.1113/Jphysiol.1979.Sp012664  0.607
1979 Gage PW, Hamill OP, Van Helden DF, Barry PH. Acetylcholine receptors Muscle and Nerve. 2: 314.  0.437
1978 Hamill OP, Adams DJ, Gage PW. An effect of ethanol at a glutamate synapse Clinical and Experimental Pharmacology and Physiology. 5: 275-276. DOI: 10.1111/J.1440-1681.1978.Tb00677.X  0.553
1977 Van Helden D, Hamill OP, Gage PW. Permeant cations alter endplate channel characteristics. Nature. 269: 711-3. PMID 413051 DOI: 10.1038/269711A0  0.657
1977 Adams DJ, Gage PW, Hamill OP. Ethanol reduces excitatory postsynaptic current duration at a crustacean neuromuscular junction. Nature. 266: 739-41. PMID 195212 DOI: 10.1038/266739A0  0.627
1977 Hamill OP, Gage PW, Spence I. Influence of temperature on the effect produced by a general anaesthetic at the post synaptic membrane Clinical and Experimental Pharmacology and Physiology. 4: 210.  0.502
1977 Torda TA, Hamill O, Gage PW. The mode of action of general anaesthetics Anaesthesia and Intensive Care. 5: 392.  0.434
1976 Adams DJ, Gage PW, Hamill OP. Voltage sensitivity of inhibitory postsynaptic current in Aplysia buccal ganglia. Brain Research. 115: 506-11. PMID 974759 DOI: 10.1016/0006-8993(76)90368-1  0.613
1976 Gage PW, Hamill OP. Effects of several inhalation anaesthetics on the kinetics of postsynaptic conductance changes in mouse diaphragm. British Journal of Pharmacology. 57: 263-72. PMID 938796 DOI: 10.1111/J.1476-5381.1976.Tb07476.X  0.584
1975 Gage PW, Hamill O. General anaesthetics: synaptic depression consistent with increased membrane fluidity. Neuroscience Letters. 1: 61-5. PMID 19604753 DOI: 10.1016/0304-3940(75)90013-0  0.581
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