John Fahy - Publications

Affiliations: 
Medicine University of California, San Francisco, San Francisco, CA 

96 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Tattersall MC, Lee KE, Tsuchiya N, Osman F, Korcarz CE, Hansen KM, Peters MC, Fahy JV, Longhurst CA, Dunican E, Wentzel SE, Leader JK, Israel E, Levy BD, Castro M, et al. Skeletal Muscle Adiposity and Lung Function Trajectory in the Severe Asthma Research Program (SARP). American Journal of Respiratory and Critical Care Medicine. PMID 36194556 DOI: 10.1164/rccm.202203-0597OC  0.4
2022 Wang Z, Xu W, Comhair SAA, Fu X, Shao Z, Bearden R, Zein JG, Bleecker ER, Castro M, Denlinger LC, Fahy JV, Israel E, Levy BD, Jarjour NN, Moore WC, et al. Urinary total conjugated 3-bromotyrosine, asthma severity and exacerbation risk. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 36126269 DOI: 10.1152/ajplung.00141.2022  0.481
2022 Li X, Guerra S, Ledford JG, Kraft M, Li H, Hastie AT, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston B, Israel E, Jarjour NN, Levy BD, Mauger DT, et al. Low CC16 mRNA Expression Levels in Bronchial Epithelial Cells Are Associated with Asthma Severity. American Journal of Respiratory and Critical Care Medicine. PMID 36066606 DOI: 10.1164/rccm.202206-1230OC  0.471
2022 Peters MC, Schiebler M, Cardet JC, Johansson MW, Sorkness R, DeBoer MD, Bleecker ER, Meyers DA, Castro M, Sumino K, Erzurum SC, Tattersall MC, Zein JG, Hastie AT, Moore W, ... ... Fahy JV, et al. The Impact of Insulin Resistance on Loss of Lung Function and Response to Treatment in Asthma. American Journal of Respiratory and Critical Care Medicine. PMID 35687105 DOI: 10.1164/rccm.202112-2745OC  0.303
2022 Izquierdo ME, Marion CR, Moore WC, Raraigh K, Taylor-Cousar JL, Cutting GR, Ampleford E, Hawkins GA, Zein J, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Israel E, Jarjour NN, et al. DNA Sequencing Analysis of Cystic Fibrosis Transmembrane Regulator Gene Identifies Cystic Fibrosis-Associated Variants in the Severe Asthma Research Program. Pediatric Pulmonology. PMID 35451201 DOI: 10.1002/ppul.25939  0.436
2022 Tang M, Elicker BM, Henry T, Gierada DS, Schiebler ML, Huang BK, Peters MC, Castro M, Hoffman EA, Fain SB, Ash SY, Choi J, Hall C, Phillips BR, Mauger DT, ... ... Fahy JV, et al. Mucus Plugs Persist in Asthma and Changes in Mucus Plugs Associate with Changes in Airflow Over Time. American Journal of Respiratory and Critical Care Medicine. PMID 35104436 DOI: 10.1164/rccm.202110-2265OC  0.392
2021 Mummy DG, Dunican EM, Carey KJ, Evans MD, Elicker BM, Newell JD, Gierada DS, Nagle SK, Schiebler ML, Sorkness RL, Jarjour NN, Denlinger LC, Fahy JV, Fain SB. Mucus Plugs in Asthma at CT Associated with Regional Ventilation Defects at Helium 3 MRI. Radiology. 204616. PMID 34931858 DOI: 10.1148/radiol.2021204616  0.361
2021 Georas SN, Wright RJ, Ivanova A, Israel E, LaVange LM, Akuthota P, Carr TF, Denlinger LC, Fajt ML, Kumar R, O'Neal WK, Phipatanakul W, Szefler SJ, Aronica MA, Bacharier LB, ... ... Fahy JV, et al. The Precision Interventions for Severe and/or Exacerbation-Prone (PrecISE) Asthma Network: an overview of Network organization, procedures and interventions. The Journal of Allergy and Clinical Immunology. PMID 34848210 DOI: 10.1016/j.jaci.2021.10.035  0.433
2021 Nagasaki T, Schuyler AJ, Zhao J, Samovich SN, Yamada K, Deng Y, Ginebaugh SP, Christenson SA, Woodruff PG, Fahy JV, Trudeau JB, Stoyanovsky D, Ray A, Tyurina YY, Kagan VE, et al. 15LO1 dictates glutathione redox changes in asthmatic airway epithelium to worsen type-2 inflammation. The Journal of Clinical Investigation. PMID 34762602 DOI: 10.1172/JCI151685  0.385
2021 Zein JG, McManus JM, Sharifi N, Erzurum SC, Marozkina N, Lahm T, Giddings O, Davis MD, DeBoer MD, Comhair SA, Bazeley P, Kim HJ, Busse W, Calhoun W, Castro M, ... ... Fahy JV, et al. Benefits of Airway Androgen Receptor Expression in Human Asthma. American Journal of Respiratory and Critical Care Medicine. PMID 33779531 DOI: 10.1164/rccm.202009-3720OC  0.429
2021 Israel E, Denlinger LC, Bacharier LB, LaVange LM, Moore WC, Peters MC, Georas SN, Wright RJ, Mauger DT, Noel P, Akuthota P, Bach J, Bleecker ER, Cardet JC, Carr TF, ... ... Fahy JV, et al. PrecISE: Precision Medicine in Severe Asthma An Adaptive Platform Trial with Biomarker Ascertainment. The Journal of Allergy and Clinical Immunology. PMID 33667479 DOI: 10.1016/j.jaci.2021.01.037  0.361
2021 Krings JG, Goss CW, Lew D, Samant M, McGregor MC, Boomer J, Bacharier LB, Sheshadri A, Hall C, Brownell J, Schechtman KB, Peterson S, McEleney S, Mauger DT, Fahy JV, et al. Quantitative CT metrics are associated with longitudinal lung function decline and future asthma exacerbations: results from SARP-3. The Journal of Allergy and Clinical Immunology. PMID 33577895 DOI: 10.1016/j.jaci.2021.01.029  0.397
2021 Hastie AT, Mauger DT, Denlinger LC, Coverstone A, Castro M, Erzurum S, Jarjour N, Levy BD, Meyers DA, Moore WC, Phillips BR, Wenzel SE, Fahy JV, Israel E, Bleecker ER, et al. Mixed Sputum Granulocyte Longitudinal Impact on Lung Function in the Severe Asthma Research Program. American Journal of Respiratory and Critical Care Medicine. PMID 33545021 DOI: 10.1164/rccm.202009-3713OC  0.432
2020 Peters MC, Fahy JV. Erratum: COVID-19-related Genes in Sputum Cells in Asthma: Relationship to Demographic Features and Corticosteroids. American Journal of Respiratory and Critical Care Medicine. 202: 1744-1746. PMID 33320072 DOI: 10.1164/rccm.v202erratum7  0.417
2020 Denlinger LC, Phillips BR, Sorkness RL, Bleecker ER, Castro M, DeBoer MD, Fitzpatrick AM, Hastie AT, Gaffin JM, Moore WC, Peters MC, Peters SP, Phipatanakul W, Cardet JC, Erzurum SC, ... Fahy JV, et al. Responsiveness to Parenteral Corticosteroids and Lung Function Trajectory in Adults with Moderate to Severe Asthma. American Journal of Respiratory and Critical Care Medicine. PMID 33290668 DOI: 10.1164/rccm.202002-0454OC  0.376
2020 Li X, Christenson SA, Modena B, Li H, Busse WW, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston B, Hastie AT, Israel E, Jarjour NN, Levy BD, Moore WC, et al. Genetic analyses identify GSDMB associated with asthma severity, exacerbations, and antiviral pathways. The Journal of Allergy and Clinical Immunology. PMID 32795586 DOI: 10.1016/J.Jaci.2020.07.030  0.359
2020 Peters MC, Mauger D, Ross KR, Phillips B, Gaston B, Cardet JC, Israel E, Levy BD, Phipatanakul W, Jarjour NN, Castro M, Wenzel SE, Hastie A, Moore W, Bleecker E, ... Fahy JV, et al. Evidence for Exacerbation-Prone Asthma and Predictive Biomarkers of Exacerbation Frequency. American Journal of Respiratory and Critical Care Medicine. PMID 32479111 DOI: 10.1164/rccm.201909-1813OC  0.41
2020 Peters MC, Sajuthi S, Deford P, Christenson S, Rios CL, Montgomery MT, Woodruff PG, Mauger DT, Erzurum SC, Johansson MW, Denlinger LC, Jarjour NN, Castro M, Hastie AT, Moore W, ... ... Fahy JV, et al. COVID-19 Related Genes in Sputum Cells in Asthma: Relationship to Demographic Features and Corticosteroids. American Journal of Respiratory and Critical Care Medicine. PMID 32348692 DOI: 10.1164/Rccm.202003-0821Oc  0.398
2020 Hastie AT, Mauger DT, Denlinger LC, Coverstone A, Castro M, Erzurum S, Jarjour N, Levy BD, Meyers DA, Moore WC, Phillips B, Wenzel SE, Fahy JV, Israel E, Bleecker ER, et al. Baseline sputum eosinophil+neutrophil subgroups' clinical characteristics and longitudinal trajectories for NHLBI Severe Asthma Research Program (SARP 3) Cohort. The Journal of Allergy and Clinical Immunology. PMID 32032631 DOI: 10.1016/J.Jaci.2020.01.039  0.472
2020 Maun HR, Jackman JK, Choy DF, Loyet KM, Staton TL, Jia G, Dressen A, Hackney JA, Bremer M, Walters BT, Vij R, Chen X, Trivedi NN, Morando A, Lipari MT, ... ... Fahy JV, et al. An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma. Cell. 180: 406. PMID 31978350 DOI: 10.1016/j.cell.2020.01.003  0.367
2019 Ross KR, Gupta R, DeBoer MD, Zein J, Phillips BR, Mauger DT, Li C, Myers RE, Phipatanakul W, Fitzpatrick AM, Ly NP, Bacharier LB, Jackson DJ, Celedón JC, Larkin A, ... ... Fahy JV, et al. Severe asthma during childhood and adolescence: A longitudinal study. The Journal of Allergy and Clinical Immunology. PMID 31622688 DOI: 10.1016/J.Jaci.2019.09.030  0.426
2019 Fitzpatrick AM, Szefler SJ, Mauger DT, Phillips BR, Denlinger LC, Moore WC, Sorkness RL, Wenzel SE, Gergen PJ, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Israel E, et al. Development and Initial Validation of the Asthma Severity Scoring System (ASSESS). The Journal of Allergy and Clinical Immunology. PMID 31604088 DOI: 10.1016/J.Jaci.2019.09.018  0.436
2019 Maun HR, Jackman JK, Choy DF, Loyet KM, Staton TL, Jia G, Dressen A, Hackney JA, Bremer M, Walters BT, Vij R, Chen X, Trivedi NN, Morando A, Lipari MT, ... ... Fahy JV, et al. An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma. Cell. 179: 417-431.e19. PMID 31585081 DOI: 10.1016/J.Cell.2019.09.009  0.403
2019 Ash SY, Vegas Sanchez-Ferrero G, Schiebler ML, Rahaghi FN, Rai A, Come CE, Ross JC, Colon AG, Cardet JC, Bleecker ER, Castro M, Fahy JV, Fain SB, Gaston BM, Hoffman EA, et al. Estimated Ventricular Size, Asthma Severity and Exacerbations: The SARP III Cohort. Chest. PMID 31521672 DOI: 10.1016/J.Chest.2019.08.2185  0.348
2019 Li X, Hastie AT, Peters MC, Hawkins GA, Phipatanakul W, Li H, Moore WC, Busse WW, Castro M, Erzurum SC, Gaston B, Israel E, Jarjour NN, Levy BD, Wenzel SE, ... ... Fahy JV, et al. Investigation of the relationship between IL-6 and type 2 biomarkers in severe asthma. The Journal of Allergy and Clinical Immunology. PMID 31513878 DOI: 10.1016/J.Jaci.2019.08.031  0.474
2019 Fahy JV, Locksley RM. Making Asthma Crystal Clear. The New England Journal of Medicine. 381: 882-884. PMID 31461600 DOI: 10.1056/Nejmcibr1908064  0.443
2019 Coverstone AM, Bacharier LB, Wilson BS, Fitzpatrick AM, Teague WG, Phipatanakul W, Wenzel SE, Gaston BM, Bleecker ER, Moore WC, Ramratnam S, Jarjour NN, Ly NP, Fahy JV, Mauger DT, et al. Clinical significance of the bronchodilator response in children with severe asthma. Pediatric Pulmonology. PMID 31424170 DOI: 10.1002/Ppul.24473  0.417
2019 Lazarus SC, Krishnan JA, King TS, Lang JE, Blake KV, Covar R, Lugogo N, Wenzel S, Chinchilli VM, Mauger DT, Dyer AM, Boushey HA, Fahy JV, Woodruff PG, Bacharier LB, et al. Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level. The New England Journal of Medicine. PMID 31112384 DOI: 10.1056/Nejmoa1814917  0.435
2019 Schaefer N, Li X, Seibold MA, Jarjour NN, Denlinger LC, Castro M, Coverstone AM, Teague WG, Boomer J, Bleecker ER, Meyers DA, Moore WC, Hawkins GA, Fahy J, Phillips BR, et al. The effect of BPIFA1/SPLUNC1 genetic variation on its expression and function in asthmatic airway epithelium. Jci Insight. 4. PMID 30996135 DOI: 10.1172/Jci.Insight.127237  0.414
2019 Lachowicz-Scroggins ME, Dunican EM, Charbit AR, Raymond W, Looney MR, Peters MC, Gordon ED, Woodruff PG, Lefrançais E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, ... ... Fahy JV, et al. Extracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma. American Journal of Respiratory and Critical Care Medicine. PMID 30888839 DOI: 10.1164/Rccm.201810-1869Oc  0.41
2019 Fitzpatrick AM, Gillespie SE, Mauger DT, Phillips BR, Bleecker ER, Israel E, Meyers DA, Moore WC, Sorkness RL, Wenzel SE, Bacharier LB, Castro M, Denlinger LC, Erzurum SC, Fahy JV, et al. Racial disparities in asthma-related health care use in the National Heart, Lung, and Blood Institute's Severe Asthma Research Program. The Journal of Allergy and Clinical Immunology. PMID 30635198 DOI: 10.1016/j.jaci.2018.11.022  0.41
2018 Peters MC, Ringel L, Dyjack N, Herrin R, Woodruff PG, Rios C, O'Connor B, Fahy JV, Seibold MA. A Transcriptomic Method to Determine Airway Immune Dysfunction in T2-High and T2-Low Asthma. American Journal of Respiratory and Critical Care Medicine. PMID 30371106 DOI: 10.1164/Rccm.201807-1291Oc  0.403
2018 Krishnamoorthy N, Douda DN, Brüggemann TR, Ricklefs I, Duvall MG, Abdulnour RE, Martinod K, Tavares L, Wang X, Cernadas M, Israel E, Mauger DT, Bleecker ER, Castro M, Erzurum SC, ... ... Fahy JV, et al. Neutrophil cytoplasts induce T17 differentiation and skew inflammation toward neutrophilia in severe asthma. Science Immunology. 3. PMID 30076281 DOI: 10.1126/Sciimmunol.Aao4747  0.511
2018 DeBoer MD, Phillips BR, Mauger DT, Zein J, Erzurum SC, Fitzpatrick AM, Gaston BM, Myers R, Ross KR, Chmiel J, Lee MJ, Fahy JV, Peters M, Ly NP, Wenzel SE, et al. Effects of endogenous sex hormones on lung function and symptom control in adolescents with asthma. Bmc Pulmonary Medicine. 18: 58. PMID 29631584 DOI: 10.1186/S12890-018-0612-X  0.371
2018 Ricklefs I, Barkas I, Duvall MG, Cernadas M, Grossman NL, Israel E, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Denlinger LC, Mauger DT, Wenzel SE, Comhair SA, et al. ALX receptor ligands define a biochemical endotype for severe asthma. Jci Insight. 3. PMID 29563345 DOI: 10.1172/jci.insight.120932  0.373
2018 Peters MC, Kerr S, Dunican EM, Woodruff PG, Fajt ML, Levy BD, Israel E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, Coverstone AM, Castro M, ... ... Fahy JV, et al. Refractory Airway Type-2 Inflammation in a Large Subgroup of Asthmatics treated with Inhaled Corticosteroids. The Journal of Allergy and Clinical Immunology. PMID 29524537 DOI: 10.1016/J.Jaci.2017.12.1009  0.456
2018 Dunican EM, Elicker BM, Gierada DS, Nagle SK, Schiebler ML, Newell JD, Raymond WW, Lachowicz-Scroggins ME, Di Maio S, Hoffman EA, Castro M, Fain SB, Jarjour NN, Israel E, Levy BD, ... ... Fahy JV, et al. Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of Clinical Investigation. PMID 29400693 DOI: 10.1172/Jci95693  0.492
2017 Wong-McGrath K, Denlinger LC, Bleecker ER, Castro M, Gaston B, Israel E, Jarjour NN, Mauger DT, Peters S, Phillips BR, Wenzel SE, Fahy JV, Peters MC. Internet-based monitoring in the Severe Asthma Research Program identifies a subgroup of patients with labile asthma control. Chest. PMID 29080709 DOI: 10.1016/j.chest.2017.10.017  0.448
2017 Bhakta NR, Christenson SA, Nerella S, Solberg OD, Nguyen CP, Choy DF, Jung KL, Garudadri S, Bonser LR, Pollack JL, Zlock LT, Erle DJ, Langelier C, Derisi JL, Arron JR, ... Fahy JV, et al. Interferon-stimulated Gene Expression, Type-2 Inflammation and Endoplasmic Reticulum Stress in Asthma. American Journal of Respiratory and Critical Care Medicine. PMID 29064281 DOI: 10.1164/Rccm.201706-1070Oc  0.497
2017 Pavord ID, Beasley R, Agusti A, Anderson GP, Bel E, Brusselle G, Cullinan P, Custovic A, Ducharme FM, Fahy JV, Frey U, Gibson P, Heaney LG, Holt PG, Humbert M, et al. After asthma: redefining airways diseases. Lancet (London, England). PMID 28911920 DOI: 10.1016/S0140-6736(17)30879-6  0.479
2017 Teague WG, Phillips BR, Fahy JV, Wenzel SE, Fitzpatrick AM, Moore WC, Hastie AT, Bleecker ER, Meyers DA, Peters SP, Castro M, Coverstone AM, Bacharier LB, Ly NP, Peters MC, et al. Baseline Features of the Severe Asthma Research Program (SARP III) Cohort: Differences with Age. The Journal of Allergy and Clinical Immunology. in Practice. PMID 28866107 DOI: 10.1016/J.Jaip.2017.05.032  0.39
2017 Duvall MG, Barnig C, Cernadas M, Ricklefs I, Krishnamoorthy N, Grossman NL, Bhakta NR, Fahy JV, Bleecker ER, Castro M, Erzurum SC, Gaston BM, Jarjour NN, Mauger DT, Wenzel SE, et al. Natural killer cell-mediated inflammation resolution is disabled in severe asthma. Science Immunology. 2. PMID 28783702 DOI: 10.1126/Sciimmunol.Aam5446  0.429
2017 Ricklefs I, Barkas I, Duvall MG, Cernadas M, Grossman NL, Israel E, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Denlinger LC, Mauger DT, Wenzel SE, Comhair SA, et al. ALX receptor ligands define a biochemical endotype for severe asthma. Jci Insight. 2. PMID 28724795 DOI: 10.1172/Jci.Insight.93534  0.333
2016 MacNee W, Fahy JV, Nicod LP, Kolls JK. Purpose of the Conference: 2016 Transatlantic Airway Conference. Annals of the American Thoracic Society. 13: S395. PMID 28005426 DOI: 10.1513/Annalsats.201611-900Aw  0.403
2016 Phipatanakul W, Mauger DT, Sorkness RL, Gaffin JM, Holguin F, Woodruff PG, Ly NP, Bacharier LB, Bhakta NR, Moore WC, Bleecker ER, Hastie AT, Meyers DA, Castro M, Fahy J, et al. Effects of Age and Disease Severity on Systemic Corticosteroid Responses in Asthma. American Journal of Respiratory and Critical Care Medicine. PMID 27967215 DOI: 10.1164/Rccm.201607-1453Oc  0.47
2016 Lachowicz-Scroggins ME, Yuan S, Kerr SC, Dunican EM, Yu M, Carrington SD, Fahy JV. Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma. American Journal of Respiratory and Critical Care Medicine. 194: 1296-1299. PMID 27845589 DOI: 10.1164/Rccm.201603-0526Le  0.682
2016 Luyster FS, Strollo PJ, Holguin F, Castro M, Dunican EM, Fahy J, Gaston B, Israel E, Jarjour NN, Mauger DT, Moore WC, Wenzel SE. Association between insomnia and asthma burden in the Severe Asthma Research Program (SARP) III. Chest. PMID 27720882 DOI: 10.1016/J.Chest.2016.09.020  0.423
2016 Gordon ED, Palandra J, Wesolowska-Andersen A, Ringel L, Rios CL, Lachowicz-Scroggins ME, Sharp LZ, Everman JL, MacLeod HJ, Lee JW, Mason RJ, Matthay MA, Sheldon RT, Peters MC, Nocka KH, ... Fahy JV, et al. IL1RL1 asthma risk variants regulate airway type 2 inflammation. Jci Insight. 1: e87871. PMID 27699235 DOI: 10.1172/Jci.Insight.87871  0.328
2016 Denlinger LC, Phillips BR, Ramratnam S, Ross K, Bhakta NR, Cardet JC, Castro M, Peters SP, Phipatanakul W, Aujla S, Bacharier LB, Bleecker ER, Comhair SA, Coverstone A, DeBoer M, ... ... Fahy JV, et al. Inflammatory and Co-Morbid Features of Patients with Severe Asthma and Frequent Exacerbations. American Journal of Respiratory and Critical Care Medicine. PMID 27556234 DOI: 10.1164/Rccm.201602-0419Oc  0.477
2016 Peters MC, Fahy JV. Metabolic consequences of obesity as an "outside in" mechanism of disease severity in asthma. The European Respiratory Journal. 48: 291-3. PMID 27478182 DOI: 10.1183/13993003.01132-2016  0.311
2016 Gordon ED, Simpson LJ, Rios CL, Ringel L, Lachowicz-Scroggins ME, Peters MC, Wesolowska-Andersen A, Gonzalez JR, MacLeod HJ, Christian LS, Yuan S, Barry L, Woodruff PG, Ansel KM, Nocka K, ... ... Fahy JV, et al. Alternative splicing of interleukin-33 and type 2 inflammation in asthma. Proceedings of the National Academy of Sciences of the United States of America. PMID 27432971 DOI: 10.1073/Pnas.1601914113  0.657
2016 Peters MC, McGrath KW, Hawkins GA, Hastie AT, Levy BD, Israel E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, Coverstone AM, Castro M, Holguin F, ... ... Fahy JV, et al. Plasma interleukin-6 concentrations, metabolic dysfunction, and asthma severity: a cross-sectional analysis of two cohorts. The Lancet. Respiratory Medicine. PMID 27283230 DOI: 10.1016/S2213-2600(16)30048-0  0.451
2016 Sweerus K, Lachowicz-Scroggins M, Gordon E, LaFemina M, Huang X, Parikh M, Kanegai C, Fahy JV, Frank JA. Claudin-18 deficiency is associated with airway epithelial barrier dysfunction and asthma. The Journal of Allergy and Clinical Immunology. PMID 27215490 DOI: 10.1016/j.jaci.2016.02.035  0.524
2016 Kerr SC, Fischer GJ, Sinha M, McCabe O, Palmer JM, Choera T, Yun Lim F, Wimmerova M, Carrington SD, Yuan S, Lowell CA, Oscarson S, Keller NP, Fahy JV. FleA Expression in Aspergillus fumigatus Is Recognized by Fucosylated Structures on Mucins and Macrophages to Prevent Lung Infection. Plos Pathogens. 12: e1005555. PMID 27058347 DOI: 10.1371/Journal.Ppat.1005555  0.563
2015 Levy BD, Noel PJ, Freemer MM, Cloutier MM, Georas SN, Jarjour NN, Ober C, Woodruff PG, Barnes KC, Bender BG, Camargo CA, Chupp GL, Denlinger LC, Fahy JV, Fitzpatrick AM, et al. Future Research Directions in Asthma: An NHLBI Working Group Report. American Journal of Respiratory and Critical Care Medicine. PMID 26305520 DOI: 10.1164/rccm.201505-0963WS  0.43
2015 Yuan S, Hollinger M, Lachowicz-Scroggins ME, Kerr SC, Dunican EM, Daniel BM, Ghosh S, Erzurum SC, Willard B, Hazen SL, Huang X, Carrington SD, Oscarson S, Fahy JV. Oxidation increases mucin polymer cross-links to stiffen airway mucus gels. Science Translational Medicine. 7: 276ra27. PMID 25717100 DOI: 10.1126/Scitranslmed.3010525  0.59
2014 Greer AM, Matthay MA, Kukreja J, Bhakta NR, Nguyen CP, Wolters PJ, Woodruff PG, Fahy JV, Shin JS. Accumulation of BDCA1⁺ dendritic cells in interstitial fibrotic lung diseases and Th2-high asthma. Plos One. 9: e99084. PMID 24915147 DOI: 10.1371/Journal.Pone.0099084  0.324
2014 Jackson DJ, Hartert TV, Martinez FD, Weiss ST, Fahy JV. Asthma: NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases. Annals of the American Thoracic Society. 11: S139-45. PMID 24754822 DOI: 10.1513/Annalsats.201312-448Ld  0.439
2014 Kerr SC, Carrington SD, Oscarson S, Gallagher ME, Solon M, Yuan S, Ahn JN, Dougherty RH, Finkbeiner WE, Peters MC, Fahy JV. Intelectin-1 is a prominent protein constituent of pathologic mucus associated with eosinophilic airway inflammation in asthma. American Journal of Respiratory and Critical Care Medicine. 189: 1005-7. PMID 24735037 DOI: 10.1164/rccm.201312-2220LE  0.686
2014 Peters MC, Mekonnen ZK, Yuan S, Bhakta NR, Woodruff PG, Fahy JV. Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma. The Journal of Allergy and Clinical Immunology. 133: 388-94. PMID 24075231 DOI: 10.1016/J.Jaci.2013.07.036  0.644
2013 Peters MC, Fahy JV. Type 2 immune responses in obese individuals with asthma. American Journal of Respiratory and Critical Care Medicine. 188: 633-4. PMID 24032378 DOI: 10.1164/rccm.201307-1360ED  0.306
2013 Bhakta NR, Solberg OD, Nguyen CP, Nguyen CN, Arron JR, Fahy JV, Woodruff PG. A qPCR-based metric of Th2 airway inflammation in asthma. Clinical and Translational Allergy. 3: 24. PMID 23866775 DOI: 10.1186/2045-7022-3-24  0.493
2013 Denlinger LC, Manthei DM, Seibold MA, Ahn K, Bleecker E, Boushey HA, Calhoun WJ, Castro M, Chinchili VM, Fahy JV, Hawkins GA, Icitovic N, Israel E, Jarjour NN, King T, et al. P2X7-regulated protection from exacerbations and loss of control is independent of asthma maintenance therapy. American Journal of Respiratory and Critical Care Medicine. 187: 28-33. PMID 23144325 DOI: 10.1164/Rccm.201204-0750Oc  0.393
2012 Huang F, Zhang H, Wu M, Yang H, Kudo M, Peters CJ, Woodruff PG, Solberg OD, Donne ML, Huang X, Sheppard D, Fahy JV, Wolters PJ, Hogan BL, Finkbeiner WE, et al. Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction. Proceedings of the National Academy of Sciences of the United States of America. 109: 16354-9. PMID 22988107 DOI: 10.1073/Pnas.1214596109  0.388
2012 Calhoun WJ, Ameredes BT, King TS, Icitovic N, Bleecker ER, Castro M, Cherniack RM, Chinchilli VM, Craig T, Denlinger L, DiMango EA, Engle LL, Fahy JV, Grant JA, Israel E, et al. Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: the BASALT randomized controlled trial. Jama. 308: 987-97. PMID 22968888 DOI: 10.1001/2012.Jama.10893  0.359
2012 Jia G, Erickson RW, Choy DF, Mosesova S, Wu LC, Solberg OD, Shikotra A, Carter R, Audusseau S, Hamid Q, Bradding P, Fahy JV, Woodruff PG, Harris JM, Arron JR, et al. Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients. The Journal of Allergy and Clinical Immunology. 130: 647-654.e10. PMID 22857879 DOI: 10.1016/J.Jaci.2012.06.025  0.454
2012 Diez D, Goto S, Fahy JV, Erle DJ, Woodruff PG, Wheelock Ã…M, Wheelock CE. Network analysis identifies a putative role for the PPAR and type 1 interferon pathways in glucocorticoid actions in asthmatics. Bmc Medical Genomics. 5: 27. PMID 22713245 DOI: 10.1186/1755-8794-5-27  0.321
2012 Sutherland ER, Goleva E, King TS, Lehman E, Stevens AD, Jackson LP, Stream AR, Fahy JV, Leung DY. Cluster analysis of obesity and asthma phenotypes. Plos One. 7: e36631. PMID 22606276 DOI: 10.1371/journal.pone.0036631  0.377
2012 Szefler SJ, Wenzel S, Brown R, Erzurum SC, Fahy JV, Hamilton RG, Hunt JF, Kita H, Liu AH, Panettieri RA, Schleimer RP, Minnicozzi M. Asthma outcomes: biomarkers. The Journal of Allergy and Clinical Immunology. 129: S9-23. PMID 22386512 DOI: 10.1016/J.Jaci.2011.12.979  0.4
2012 McGrath KW, Icitovic N, Boushey HA, Lazarus SC, Sutherland ER, Chinchilli VM, Fahy JV. A large subgroup of mild-to-moderate asthma is persistently noneosinophilic. American Journal of Respiratory and Critical Care Medicine. 185: 612-9. PMID 22268133 DOI: 10.1164/Rccm.201109-1640Oc  0.495
2011 Fahy JV, Locksley RM. The airway epithelium as a regulator of Th2 responses in asthma. American Journal of Respiratory and Critical Care Medicine. 184: 390-2. PMID 21844510 DOI: 10.1164/Rccm.201107-1258Ed  0.486
2011 Choy DF, Modrek B, Abbas AR, Kummerfeld S, Clark HF, Wu LC, Fedorowicz G, Modrusan Z, Fahy JV, Woodruff PG, Arron JR. Gene expression patterns of Th2 inflammation and intercellular communication in asthmatic airways. Journal of Immunology (Baltimore, Md. : 1950). 186: 1861-9. PMID 21187436 DOI: 10.4049/jimmunol.1002568  0.488
2011 Innes AL, McGrath KW, Dougherty RH, McCulloch CE, Woodruff PG, Seibold MA, Okamoto KS, Ingmundson KJ, Solon MC, Carrington SD, Fahy JV. The H antigen at epithelial surfaces is associated with susceptibility to asthma exacerbation. American Journal of Respiratory and Critical Care Medicine. 183: 189-94. PMID 20732988 DOI: 10.1164/Rccm.201003-0488Oc  0.461
2010 Peters SP, Kunselman SJ, Icitovic N, Moore WC, Pascual R, Ameredes BT, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Craig T, Denlinger L, Engle LL, DiMango EA, Fahy JV, et al. Tiotropium bromide step-up therapy for adults with uncontrolled asthma. The New England Journal of Medicine. 363: 1715-26. PMID 20979471 DOI: 10.1056/Nejmoa1008770  0.407
2010 Sutherland ER, King TS, Icitovic N, Ameredes BT, Bleecker E, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Chinchilli VM, Craig TJ, Denlinger L, DiMango EA, Fahy JV, Israel E, et al. A trial of clarithromycin for the treatment of suboptimally controlled asthma. The Journal of Allergy and Clinical Immunology. 126: 747-53. PMID 20920764 DOI: 10.1016/J.Jaci.2010.07.024  0.459
2010 Sidhu SS, Yuan S, Innes AL, Kerr S, Woodruff PG, Hou L, Muller SJ, Fahy JV. Roles of epithelial cell-derived periostin in TGF-beta activation, collagen production, and collagen gel elasticity in asthma. Proceedings of the National Academy of Sciences of the United States of America. 107: 14170-5. PMID 20660732 DOI: 10.1073/Pnas.1009426107  0.641
2010 Dougherty RH, Sidhu SS, Raman K, Solon M, Solberg OD, Caughey GH, Woodruff PG, Fahy JV. Accumulation of intraepithelial mast cells with a unique protease phenotype in T(H)2-high asthma. The Journal of Allergy and Clinical Immunology. 125: 1046-1053.e8. PMID 20451039 DOI: 10.1016/J.Jaci.2010.03.003  0.4
2009 Park SW, Verhaeghe C, Nguyenvu LT, Barbeau R, Eisley CJ, Nakagami Y, Huang X, Woodruff PG, Fahy JV, Erle DJ. Distinct roles of FOXA2 and FOXA3 in allergic airway disease and asthma. American Journal of Respiratory and Critical Care Medicine. 180: 603-10. PMID 19628779 DOI: 10.1164/rccm.200811-1768OC  0.493
2009 Woodruff PG, Modrek B, Choy DF, Jia G, Abbas AR, Ellwanger A, Koth LL, Arron JR, Fahy JV. T-helper type 2-driven inflammation defines major subphenotypes of asthma. American Journal of Respiratory and Critical Care Medicine. 180: 388-95. PMID 19483109 DOI: 10.1164/rccm.200903-0392OC  0.425
2009 Innes AL, Carrington SD, Thornton DJ, Kirkham S, Rousseau K, Dougherty RH, Raymond WW, Caughey GH, Muller SJ, Fahy JV. Ex vivo sputum analysis reveals impairment of protease-dependent mucus degradation by plasma proteins in acute asthma. American Journal of Respiratory and Critical Care Medicine. 180: 203-10. PMID 19423716 DOI: 10.1164/Rccm.200807-1056Oc  0.457
2008 Seibold MA, Donnelly S, Solon M, Innes A, Woodruff PG, Boot RG, Burchard EG, Fahy JV. Chitotriosidase is the primary active chitinase in the human lung and is modulated by genotype and smoking habit. The Journal of Allergy and Clinical Immunology. 122: 944-950.e3. PMID 18845328 DOI: 10.1016/J.Jaci.2008.08.023  0.425
2007 Woodruff PG, Boushey HA, Dolganov GM, Barker CS, Yang YH, Donnelly S, Ellwanger A, Sidhu SS, Dao-Pick TP, Pantoja C, Erle DJ, Yamamoto KR, Fahy JV. Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids. Proceedings of the National Academy of Sciences of the United States of America. 104: 15858-63. PMID 17898169 DOI: 10.1073/Pnas.0707413104  0.515
2007 Martin RJ, Szefler SJ, King TS, Kraft M, Boushey HA, Chinchilli VM, Craig TJ, Dimango EA, Deykin A, Fahy JV, Israel E, Lazarus SC, Lemanske RF, Leone FT, Pesola GR, et al. The Predicting Response to Inhaled Corticosteroid Efficacy (PRICE) trial. The Journal of Allergy and Clinical Immunology. 119: 73-80. PMID 17208587 DOI: 10.1016/J.Jaci.2006.10.035  0.437
2007 Lazarus SC, Chinchilli VM, Rollings NJ, Boushey HA, Cherniack R, Craig TJ, Deykin A, DiMango E, Fish JE, Ford JG, Israel E, Kiley J, Kraft M, Lemanske RF, Leone FT, ... ... Fahy JV, et al. Smoking affects response to inhaled corticosteroids or leukotriene receptor antagonists in asthma. American Journal of Respiratory and Critical Care Medicine. 175: 783-90. PMID 17204725 DOI: 10.1164/Rccm.200511-1746Oc  0.399
2007 Deykin A, Wechsler ME, Boushey HA, Chinchilli VM, Kunselman SJ, Craig TJ, DiMango E, Fahy JV, Kraft M, Leone F, Lazarus SC, Lemanske RF, Martin RJ, Pesola GR, Peters SP, et al. Combination therapy with a long-acting beta-agonist and a leukotriene antagonist in moderate asthma. American Journal of Respiratory and Critical Care Medicine. 175: 228-34. PMID 16973987 DOI: 10.1164/Rccm.200601-112Oc  0.407
2006 Innes AL, Woodruff PG, Ferrando RE, Donnelly S, Dolganov GM, Lazarus SC, Fahy JV. Epithelial mucin stores are increased in the large airways of smokers with airflow obstruction. Chest. 130: 1102-8. PMID 17035444 DOI: 10.1378/chest.130.4.1102  0.342
2005 Kuperman DA, Lewis CC, Woodruff PG, Rodriguez MW, Yang YH, Dolganov GM, Fahy JV, Erle DJ. Dissecting asthma using focused transgenic modeling and functional genomics. The Journal of Allergy and Clinical Immunology. 116: 305-11. PMID 16083784 DOI: 10.1016/j.jaci.2005.03.024  0.404
2005 Boushey HA, Sorkness CA, King TS, Sullivan SD, Fahy JV, Lazarus SC, Chinchilli VM, Craig TJ, Dimango EA, Deykin A, Fagan JK, Fish JE, Ford JG, Kraft M, Lemanske RF, et al. Daily versus as-needed corticosteroids for mild persistent asthma. The New England Journal of Medicine. 352: 1519-28. PMID 15829533 DOI: 10.1056/Nejmoa042552  0.375
2005 Deykin A, Lazarus SC, Fahy JV, Wechsler ME, Boushey HA, Chinchilli VM, Craig TJ, Dimango E, Kraft M, Leone F, Lemanske RF, Martin RJ, Pesola GR, Peters SP, Sorkness CA, et al. Sputum eosinophil counts predict asthma control after discontinuation of inhaled corticosteroids. The Journal of Allergy and Clinical Immunology. 115: 720-7. PMID 15805990 DOI: 10.1016/J.Jaci.2004.12.1129  0.47
2004 McNamara N, Gallup M, Khong A, Sucher A, Maltseva I, Fahy J, Basbaum C. Adenosine up-regulation of the mucin gene, MUC2, in asthma. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1770-2. PMID 15345696 DOI: 10.1096/Fj.04-1964Fje  0.409
2004 Djukanovi? R, Wilson SJ, Kraft M, Jarjour NN, Steel M, Chung KF, Bao W, Fowler-Taylor A, Matthews J, Busse WW, Holgate ST, Fahy JV. Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma. American Journal of Respiratory and Critical Care Medicine. 170: 583-93. PMID 15172898 DOI: 10.1164/rccm.200312-1651OC  0.492
2004 Woodruff PG, Dolganov GM, Ferrando RE, Donnelly S, Hays SR, Solberg OD, Carter R, Wong HH, Cadbury PS, Fahy JV. Hyperplasia of smooth muscle in mild to moderate asthma without changes in cell size or gene expression. American Journal of Respiratory and Critical Care Medicine. 169: 1001-6. PMID 14726423 DOI: 10.1164/Rccm.200311-1529Oc  0.39
2003 Janson SL, Fahy JV, Covington JK, Paul SM, Gold WM, Boushey HA. Effects of individual self-management education on clinical, biological, and adherence outcomes in asthma. The American Journal of Medicine. 115: 620-6. PMID 14656614 DOI: 10.1016/J.Amjmed.2003.07.008  0.336
2003 Hays SR, Fahy JV. The role of mucus in fatal asthma. The American Journal of Medicine. 115: 68-9. PMID 12867239 DOI: 10.1016/S0002-9343(03)00260-2  0.499
2003 Kraft M, Martin RJ, Lazarus SC, Fahy JV, Boushey HA, Lemanske RF, Szefler SJ. Airway tissue mast cells in persistent asthma: predictor of treatment failure when patients discontinue inhaled corticosteroids. Chest. 124: 42-50. PMID 12853500 DOI: 10.1378/chest.124.1.42  0.369
2002 Szefler SJ, Martin RJ, King TS, Boushey HA, Cherniack RM, Chinchilli VM, Craig TJ, Dolovich M, Drazen JM, Fagan JK, Fahy JV, Fish JE, Ford JG, Israel E, Kiley J, et al. Significant variability in response to inhaled corticosteroids for persistent asthma. The Journal of Allergy and Clinical Immunology. 109: 410-8. PMID 11897984 DOI: 10.1067/Mai.2002.122635  0.401
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