Year |
Citation |
Score |
2023 |
Alexander SPH, Christopoulos A, Davenport AP, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA, Abbracchio MP, Abraham G, Agoulnik A, Alexander W, et al. The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors. British Journal of Pharmacology. S23-S144. PMID 38123151 DOI: 10.1111/bph.16177 |
0.735 |
|
2023 |
Williams TL, Macrae RGC, Kuc RE, Brown AJH, Maguire JJ, Davenport AP. Expanding the apelin receptor pharmacological toolbox using novel fluorescent ligands. Frontiers in Endocrinology. 14: 1139121. PMID 36967803 DOI: 10.3389/fendo.2023.1139121 |
0.322 |
|
2022 |
Abraham GR, Nyimanu D, Kuc RE, Maguire JJ, Davenport AP, Hoole SP. Trans-myocardial Extraction of Endothelin-1 Correlates with Increased Microcirculatory Resistance following Percutaneous Coronary Intervention. Journal of Interventional Cardiology. 2022: 9154048. PMID 36262459 DOI: 10.1155/2022/9154048 |
0.687 |
|
2022 |
Macrae RGC, Colzani MT, Williams TL, Bayraktar S, Kuc RE, Pullinger AL, Bernard WG, Robinson EL, Davenport EE, Maguire JJ, Sinha S, Davenport AP. Inducible apelin receptor knockdown reduces differentiation efficiency and contractility of hESC-derived cardiomyocytes. Cardiovascular Research. PMID 36239923 DOI: 10.1093/cvr/cvac065 |
0.324 |
|
2022 |
Nyimanu D, Chapman FA, Gallacher PJ, Kuc RE, Williams TL, Newby DE, Maguire JJ, Davenport AP, Dhaun N. Apelin is expressed throughout the human kidney, is elevated in chronic kidney disease & associates independently with decline in kidney function. British Journal of Clinical Pharmacology. PMID 35748053 DOI: 10.1111/bcp.15446 |
0.724 |
|
2021 |
Williams TL, Strachan G, Macrae RGC, Kuc RE, Nyimanu D, Paterson AL, Sinha S, Maguire JJ, Davenport AP. Differential expression in humans of the viral entry receptor ACE2 compared with the short deltaACE2 isoform lacking SARS-CoV-2 binding sites. Scientific Reports. 11: 24336. PMID 34934117 DOI: 10.1038/s41598-021-03731-9 |
0.724 |
|
2021 |
Alexander SP, Christopoulos A, Davenport AP, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Southan C, Davies JA, Abbracchio MP, Alexander W, et al. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors. British Journal of Pharmacology. 178: S27-S156. PMID 34529832 DOI: 10.1111/bph.15538 |
0.735 |
|
2021 |
Nyimanu D, Kay RG, Kuc RE, Brown AJH, Gribble FM, Maguire JJ, Davenport AP. In vitro metabolism of synthetic Elabela/Toddler (ELA-32) peptide in human plasma and kidney homogenates analyzed with mass spectrometry and validation of endogenous peptide quantification in tissues by ELISA. Peptides. 170642. PMID 34455010 DOI: 10.1016/j.peptides.2021.170642 |
0.736 |
|
2021 |
Chapman FA, Nyimanu D, Maguire JJ, Davenport AP, Newby DE, Dhaun N. The therapeutic potential of apelin in kidney disease. Nature Reviews. Nephrology. PMID 34389827 DOI: 10.1038/s41581-021-00461-z |
0.732 |
|
2021 |
Williams TL, Colzani MT, Macrae RGC, Robinson EL, Bloor S, Greenwood EJD, Zhan JR, Strachan G, Kuc RE, Nyimanu D, Maguire JJ, Lehner PJ, Sinha S, Davenport AP. Human embryonic stem cell-derived cardiomyocyte platform screens inhibitors of SARS-CoV-2 infection. Communications Biology. 4: 926. PMID 34326460 DOI: 10.1038/s42003-021-02453-y |
0.693 |
|
2020 |
Read C, Nyimanu D, Yang P, Kuc RE, Williams TL, Fitzpatrick CM, Foster R, Glen RC, Maguire JJ, Davenport AP. The G Protein Biased Small Molecule Apelin Agonist CMF-019 is Disease Modifying in Endothelial Cell Apoptosis and Induces Vasodilatation Without Desensitisation . Frontiers in Pharmacology. 11: 588669. PMID 33716722 DOI: 10.3389/fphar.2020.588669 |
0.775 |
|
2020 |
Owen NE, Nyimanu D, Kuc RE, Upton PD, Morrell NW, Alexander GJ, Maguire JJ, Davenport AP. Plasma levels of apelin are reduced in patients with liver fibrosis and cirrhosis but are not correlated with circulating levels of bone morphogenetic protein 9 and 10. Peptides. 170440. PMID 33171278 DOI: 10.1016/j.peptides.2020.170440 |
0.711 |
|
2019 |
Nyimanu D, Kay RG, Sulentic P, Kuc RE, Ambery P, Jermutus L, Reimann F, Gribble FM, Cheriyan J, Maguire JJ, Davenport AP. Development and validation of an LC-MS/MS method for detection and quantification of in vivo derived metabolites of [Pyr]apelin-13 in humans. Scientific Reports. 9: 19934. PMID 31882594 DOI: 10.1038/S41598-019-56157-9 |
0.712 |
|
2019 |
Read C, Nyimanu D, Williams TL, Huggins DJ, Sulentic P, Macrae RGC, Yang P, Glen RC, Maguire JJ, Davenport AP. International Union of Basic and Clinical Pharmacology. CVII. Structure and Pharmacology of the Apelin Receptor with a Recommendation that Elabela/Toddler Is a Second Endogenous Peptide Ligand. Pharmacological Reviews. 71: 467-502. PMID 31492821 DOI: 10.1124/Pr.119.017533 |
0.785 |
|
2019 |
Nyimanu D, Kuc RE, Williams TL, Bednarek M, Ambery P, Jermutus L, Maguire JJ, Davenport AP. Apelin-36-[L28A] and Apelin-36-[L28C(30kDa-PEG)] peptides that improve diet induced obesity are G Protein Biased Ligands at the Apelin Receptor. Peptides. 170139. PMID 31472173 DOI: 10.1016/J.Peptides.2019.170139 |
0.757 |
|
2019 |
Read C, Yang P, Kuc RE, Nyimanu D, Williams TL, Glen RC, Holt LJ, Arulanantham H, Smart A, Davenport AP, Maguire JJ. Apelin peptides linked to anti-serum albumin domain antibodies retain affinity in vitro and are efficacious receptor agonists in vivo. Basic & Clinical Pharmacology & Toxicology. PMID 30901161 DOI: 10.1111/Bcpt.13227 |
0.757 |
|
2019 |
Yang P, Read C, Kuc RE, Nyimanu D, Williams TL, Crosby A, Buonincontri G, Southwood M, Sawiak SJ, Morrell NW, Davenport AP, Maguire JJ. A novel cyclic biased agonist of the apelin receptor, MM07, is disease modifying in the rat monocrotaline model of pulmonary arterial hypertension. British Journal of Pharmacology. PMID 30710493 DOI: 10.1111/Bph.14603 |
0.781 |
|
2019 |
Williams T, O’Flaherty E, Nyimanu D, Macrae R, Currinn H, Brown J, Brown A, Strachan G, Gräf S, Morrell N, Maguire J, Davenport A, Kuc RE. BS46 High content high resolution confocal imaging to characterise mutations in the apelin receptor identified in patients from the 100,000 genomes project Heart. 105. DOI: 10.1136/Heartjnl-2019-Bcs.207 |
0.747 |
|
2019 |
O’Flaherty E, Williams T, Nyimanu D, Macrae R, Currinn H, Brown J, Brown A, Strachan G, Maguire J, Davenport A. BS16 A novel fluorescent apelin ligand tracks apelin receptor internalisation Heart. DOI: 10.1136/Heartjnl-2019-Bcs.179 |
0.736 |
|
2018 |
Davenport A, Kuc R, Southan C, Maguire J. New drugs and emerging therapeutic targets in the endothelin signaling pathway and prospects for personalized precision medicine. Physiological Research. 67. PMID 29947527 DOI: 10.33549/Physiolres.933872 |
0.424 |
|
2018 |
Kennedy AJ, Davenport AP. International Union of Basic and Clinical Pharmacology CIII: Chemerin Receptors CMKLR1 (Chemerin1) and GPR1 (Chemerin2) Nomenclature, Pharmacology, and Function. Pharmacological Reviews. 70: 174-196. PMID 29279348 DOI: 10.1124/pr.116.013177 |
0.34 |
|
2017 |
Yang P, Read C, Kuc RE, Buonincontri G, Southwood M, Torella R, Upton PD, Crosby A, Sawiak SJ, Carpenter TA, Glen RC, Morrell NW, Maguire JJ, Davenport AP. Elabela/Toddler is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of its Expression in Pulmonary Arterial Hypertension. Circulation. PMID 28137936 DOI: 10.1161/Circulationaha.116.023218 |
0.607 |
|
2016 |
Kennedy AJ, Yang P, Read C, Kuc RE, Yang L, Taylor EJ, Taylor CW, Maguire JJ, Davenport AP. Chemerin Elicits Potent Constrictor Actions via Chemokine-Like Receptor 1 (CMKLR1), not G-Protein-Coupled Receptor 1 (GPR1), in Human and Rat Vasculature. Journal of the American Heart Association. 5. PMID 27742615 DOI: 10.1161/Jaha.116.004421 |
0.596 |
|
2016 |
Read C, Fitzpatrick CM, Yang P, Kuc RE, Maguire JJ, Glen RC, Foster RE, Davenport AP. Cardiac action of the first G protein biased small molecule apelin agonist. Biochemical Pharmacology. PMID 27475715 DOI: 10.1016/J.Bcp.2016.07.018 |
0.568 |
|
2016 |
Davenport AP, Hyndman KA, Dhaun N, Southan C, Kohan DE, Pollock JS, Pollock DM, Webb DJ, Maguire JJ. Endothelin. Pharmacological Reviews. 68: 357-418. PMID 26956245 DOI: 10.1124/pr.115.011833 |
0.367 |
|
2015 |
Yang P, Maguire JJ, Davenport AP. Apelin, Elabela/Toddler, and biased agonists as novel therapeutic agents in the cardiovascular system. Trends in Pharmacological Sciences. PMID 26143239 DOI: 10.1016/j.tips.2015.06.002 |
0.352 |
|
2015 |
Shaikh LH, Zhou J, Teo AE, Garg S, Neogi SG, Figg N, Yeo GS, Yu H, Maguire JJ, Zhao W, Bennett MR, Azizan EA, Davenport AP, McKenzie G, Brown MJ. LGR5 Activates Noncanonical Wnt Signaling and Inhibits Aldosterone Production in the Human Adrenal. The Journal of Clinical Endocrinology and Metabolism. 100: E836-44. PMID 25915569 DOI: 10.1210/Jc.2015-1734 |
0.377 |
|
2015 |
Brame AL, Maguire JJ, Yang P, Dyson A, Torella R, Cheriyan J, Singer M, Glen RC, Wilkinson IB, Davenport AP. Design, characterization, and first-in-human study of the vascular actions of a novel biased apelin receptor agonist. Hypertension. 65: 834-40. PMID 25712721 DOI: 10.1161/Hypertensionaha.114.05099 |
0.307 |
|
2013 |
Azizan EA, Poulsen H, Tuluc P, Zhou J, Clausen MV, Lieb A, Maniero C, Garg S, Bochukova EG, Zhao W, Shaikh LH, Brighton CA, Teo AE, Davenport AP, Dekkers T, et al. Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension. Nature Genetics. 45: 1055-60. PMID 23913004 DOI: 10.1038/Ng.2716 |
0.348 |
|
2012 |
Maguire J, Kuc R, Pell V, Davenport A. 12 Pharmacology of Human ETA and ETB Receptor Signalling VIA G-Protein and Beta-Arrestin Pathways Heart. 98. DOI: 10.1136/Heartjnl-2012-302951.012 |
0.392 |
|
2011 |
Maguire JJ, Kirby HR, Mead EJ, Kuc RE, d'Anglemont de Tassigny X, Colledge WH, Davenport AP. Inotropic action of the puberty hormone kisspeptin in rat, mouse and human: cardiovascular distribution and characteristics of the kisspeptin receptor. Plos One. 6: e27601. PMID 22132116 DOI: 10.1371/journal.pone.0027601 |
0.332 |
|
2011 |
Jones KL, Maguire JJ, Davenport AP. Chemokine receptor CCR5: from AIDS to atherosclerosis. British Journal of Pharmacology. 162: 1453-69. PMID 21133894 DOI: 10.1111/J.1476-5381.2010.01147.X |
0.407 |
|
2010 |
Kirby HR, Maguire JJ, Colledge WH, Davenport AP. International Union of Basic and Clinical Pharmacology. LXXVII. Kisspeptin receptor nomenclature, distribution, and function. Pharmacological Reviews. 62: 565-78. PMID 21079036 DOI: 10.1124/pr.110.002774 |
0.342 |
|
2010 |
Pitkin SL, Maguire JJ, Bonner TI, Davenport AP. International Union of Basic and Clinical Pharmacology. LXXIV. Apelin receptor nomenclature, distribution, pharmacology, and function. Pharmacological Reviews. 62: 331-42. PMID 20605969 DOI: 10.1124/pr.110.002949 |
0.307 |
|
2010 |
Davenport A. Management of acute kidney injury in liver disease. Contributions to Nephrology. 165: 197-205. PMID 20427970 DOI: 10.1159/000313759 |
0.3 |
|
2009 |
Vachiery J, Davenport A. The endothelin system in pulmonary and renal vasculopathy: les liaisons dangereuses. European Respiratory Review. 18: 260-271. PMID 20956151 DOI: 10.1183/09059180.00005709 |
0.383 |
|
2009 |
Mitchell JD, Maguire JJ, Davenport AP. Emerging pharmacology and physiology of neuromedin U and the structurally related peptide neuromedin S. British Journal of Pharmacology. 158: 87-103. PMID 19519756 DOI: 10.1111/J.1476-5381.2009.00252.X |
0.425 |
|
2009 |
Maguire JJ, Parker WA, Foord SM, Bonner TI, Neubig RR, Davenport AP. International Union of Pharmacology. LXXII. Recommendations for trace amine receptor nomenclature. Pharmacological Reviews. 61: 1-8. PMID 19325074 DOI: 10.1124/pr.109.001107 |
0.308 |
|
2005 |
Maguire JJ, Davenport AP. Regulation of vascular reactivity by established and emerging GPCRs. Trends in Pharmacological Sciences. 26: 448-54. PMID 16054240 DOI: 10.1016/j.tips.2005.07.007 |
0.312 |
|
2005 |
Edvinsson L, Uddman E, Wackenfors A, Davenport A, Longmore J, Malmsjö M. Triptan-induced contractile (5-HT1B receptor) responses in human cerebral and coronary arteries: relationship to clinical effect. Clinical Science (London, England : 1979). 109: 335-42. PMID 15853772 DOI: 10.1042/Cs20050016 |
0.323 |
|
2005 |
Kleinz MJ, Skepper JN, Davenport AP. Immunocytochemical localisation of the apelin receptor, APJ, to human cardiomyocytes, vascular smooth muscle and endothelial cells. Regulatory Peptides. 126: 233-40. PMID 15664671 DOI: 10.1016/j.regpep.2004.10.019 |
0.307 |
|
2004 |
Wiley KE, Davenport AP. CRF2 receptors are highly expressed in the human cardiovascular system and their cognate ligands urocortins 2 and 3 are potent vasodilators. British Journal of Pharmacology. 143: 508-14. PMID 15381637 DOI: 10.1038/sj.bjp.0705985 |
0.31 |
|
2003 |
Katugampola S, Davenport A. Emerging roles for orphan G-protein-coupled receptors in the cardiovascular system. Trends in Pharmacological Sciences. 24: 30-5. PMID 12498728 DOI: 10.1016/S0165-6147(02)00007-X |
0.454 |
|
2002 |
Katugampola SD, Kuc RE, Maguire JJ, Davenport AP. G-protein-coupled receptors in human atherosclerosis: comparison of vasoconstrictors (endothelin and thromboxane) with recently de-orphanized (urotensin-II, apelin and ghrelin) receptors. Clinical Science (London, England : 1979). 103: 171S-175S. PMID 12193079 DOI: 10.1042/CS103S171S |
0.341 |
|
1993 |
Karet F, Plumpton C, Davenport A. Characterisation of Immunoreactive Endothelin in Human kidney by RP-HPLC and RIA Clinical Science. 84. DOI: 10.1042/Cs084006Pb |
0.309 |
|
1992 |
Harcombe A, Persidis A, Davenport A, Kuc R, Plumpton C, Weissberg P. Isolation of Endothelin Receptors from Human Atrium by Mobility Shift Analysis Clinical Science. 83. DOI: 10.1042/Cs083019Pb |
0.365 |
|
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