| Year |
Citation |
Score |
| 2024 |
Zhang Y, Karagiannis D, Liu H, Lin M, Fang Y, Jiang M, Chen X, Suresh S, Huang H, She J, Shi F, Liu J, Luo D, Angel JC, Lin G, ... ... Rustgi AK, et al. Epigenetic regulation of p63 blocks squamous-to-neuroendocrine transdifferentiation in esophageal development and malignancy. Science Advances. 10: eadq0479. PMID 39383220 DOI: 10.1126/sciadv.adq0479 |
0.301 |
|
| 2023 |
Zhang Y, Karagiannis D, Liu H, Lin M, Fang Y, Jiang M, Chen X, Suresh S, Huang H, She J, Shi F, Yang P, El-Rifai W, Zaika A, Oro AE, ... Rustgi AK, et al. Epigenetic regulation of p63 blocks squamous-to-neuroendocrine transdifferentiation in esophageal development and malignancy. Biorxiv : the Preprint Server For Biology. PMID 37745439 DOI: 10.1101/2023.09.09.556982 |
0.301 |
|
| 2021 |
Tang Q, Lento A, Suzuki K, Efe G, Karakasheva T, Long A, Giroux V, Islam M, Wileyto EP, Klein-Szanto AJ, Nakagawa H, Bass A, Rustgi AK. Rab11-FIP1 mediates epithelial-mesenchymal transition and invasion in esophageal cancer. Embo Reports. e48351. PMID 33403789 DOI: 10.15252/embr.201948351 |
0.332 |
|
| 2020 |
Facompre ND, Rajagopalan P, Pearson AT, Montone KT, James CD, Gleber-Netto FO, Nakagawa H, White EA, Rustgi AK, Califano JA, Pickering CR, Windle B, Morgan IM, Gimotty PA, Basu D. Abstract A01: HPV+ oral cancer PDXs identify prognostic utility for E2F target gene expression and mutation burden Clinical Cancer Research. 26. DOI: 10.1158/1557-3265.Aacrahns19-A01 |
0.314 |
|
| 2019 |
Bailey DD, Zhang Y, van Soldt BJ, Jiang M, Suresh S, Nakagawa H, Rustgi AK, Aceves SS, Cardoso WV, Que J. Use of hPSC-derived 3D organoids and mouse genetics to define the roles of YAP in the development of the esophagus. Development (Cambridge, England). PMID 31748205 DOI: 10.1242/Dev.178855 |
0.367 |
|
| 2019 |
Sen M, Hahn F, Black TA, DeMarshall M, Porter W, Snowden E, Yee SS, Tong F, Ferguson M, Fleshman EN, Nakagawa H, Falk GW, Ginsberg GG, Kochman ML, Blaesius R, ... Rustgi AK, et al. Flow based single cell analysis of the immune landscape distinguishes Barrett's esophagus from adjacent normal tissue. Oncotarget. 10: 3592-3604. PMID 31217895 DOI: 10.18632/Oncotarget.26911 |
0.318 |
|
| 2019 |
Kumar S, Katona BW, Long JM, Domchek S, Rustgi AK, Roses R, Ginsberg GG. Endoscopic Ultrasound Has Limited Utility in Diagnosis of Gastric Cancer in Carriers of CDH1 Mutations. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 31077828 DOI: 10.1016/J.Cgh.2019.04.064 |
0.309 |
|
| 2019 |
Qie S, Yoshida A, Parnham S, Oleinik N, Beeson GC, Beeson CC, Ogretmen B, Bass AJ, Wong KK, Rustgi AK, Diehl JA. Targeting glutamine-addiction and overcoming CDK4/6 inhibitor resistance in human esophageal squamous cell carcinoma. Nature Communications. 10: 1296. PMID 30899002 DOI: 10.1038/S41467-019-09179-W |
0.373 |
|
| 2019 |
Marchand B, Pitarresi JR, Reichert M, Suzuki K, Laczkó D, Rustgi AK. PRRX1 isoforms cooperate with FOXM1 to regulate the DNA damage response in pancreatic cancer cells. Oncogene. PMID 30705403 DOI: 10.1038/S41388-019-0725-6 |
0.413 |
|
| 2019 |
Kijima T, Nakagawa H, Shimonosono M, Chandramouleeswaran PM, Hara T, Sahu V, Kasagi Y, Kikuchi O, Tanaka K, Giroux V, Muir AB, Whelan KA, Ohashi S, Naganuma S, Klein-Szanto AJ, ... ... Rustgi AK, et al. Three-Dimensional Organoids Reveal Therapy Resistance of Esophageal and Oropharyngeal Squamous Cell Carcinoma Cells. Cellular and Molecular Gastroenterology and Hepatology. 7: 73-91. PMID 30510992 DOI: 10.1016/J.Jcmgh.2018.09.003 |
0.372 |
|
| 2019 |
Pitarresi JR, Norgard RJ, Stanger BZ, Rustgi AK. Abstract B43: p120 catenin loss drives pancreatic cancer EMT and metastasis through activation of PTHrP-mediated calcium signaling Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-B43 |
0.409 |
|
| 2019 |
Norgard RJ, Maddipati R, Aiello NM, Balli D, Pitarresi JR, Rosario-Berrios DN, Li J, Yuan S, Yamazoe T, Sela Y, Merrell AJ, Wengyn MD, Sun K, Rustgi AK, Stanger BZ. Abstract B38: Calcium signaling induces a partial EMT in pancreatic ductal adenocarcinoma Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-B38 |
0.404 |
|
| 2019 |
Overbeek KA, Canto MI, Bartsch DK, Brand R, Carrato A, Chiaro MD, Farrell JJ, Fishman EK, Fockens P, Gress TM, Hooft JEv, Kastrinos F, Rustgi AK, Syngal S, Vasen HF, et al. Sa1350 – Updated International Cancer of the Pancreas Screening (CAPS) Consortium Guidelines on the Management of Patients with Increased Risk for Familial Pancreatic Cancer Gastroenterology. 156. DOI: 10.1016/S0016-5085(19)37637-1 |
0.312 |
|
| 2019 |
Kijima T, Shimonosono M, Chandramouleeswaran PM, Karakasheva T, Tang Q, Kasagi Y, Wada M, Muir AB, Whelan KA, Klein-Szanto A, Natsugoe S, Rustgi A, Nakagawa H. 529 – 3D Organoids Reveal the Expansion of Neoplastic Cell Heterogeneity During Development and Progression of Esophageal Squamous Cell Carcinoma Gastroenterology. 156: S-107. DOI: 10.1016/S0016-5085(19)37059-3 |
0.343 |
|
| 2018 |
Andres SF, Williams KN, Plesset JB, Headd JJ, Mizuno R, Chatterji P, Lento AA, Klein-Szanto AJ, Mick R, Hamilton KE, Rustgi AK. IMP1 3' UTR shortening enhances metastatic burden in colorectal cancer. Carcinogenesis. PMID 30407516 DOI: 10.1093/Carcin/Bgy153 |
0.38 |
|
| 2018 |
Brown JC, Rhim AD, Manning SL, Brennan L, Mansour AI, Rustgi AK, Damjanov N, Troxel AB, Rickels MR, Ky B, Zemel BS, Courneya KS, Schmitz KH. Effects of exercise on circulating tumor cells among patients with resected stage I-III colon cancer. Plos One. 13: e0204875. PMID 30332430 DOI: 10.1371/Journal.Pone.0204875 |
0.358 |
|
| 2018 |
Rustgi AK. 3D Human Esophageal Epithelium Steps Out from hPSCs. Cell Stem Cell. 23: 460-462. PMID 30290173 DOI: 10.1016/J.Stem.2018.09.010 |
0.327 |
|
| 2018 |
Andres SF, Williams KN, Rustgi AK. The Molecular Basis of Metastatic Colorectal Cancer. Current Colorectal Cancer Reports. 14: 69-79. PMID 30237756 DOI: 10.1007/S11888-018-0403-Z |
0.319 |
|
| 2018 |
Adeegbe DO, Liu S, Hattersley M, Bowden M, Zhou CW, Li S, Vlahos R, Grondine M, Dolgalev I, Ivanova E, Quinn MM, Gao P, Hammerman PS, Bradner JE, Diehl JA, ... Rustgi AK, et al. BET bromodomain inhibition cooperates with PD-1 blockade to facilitate antitumor response in Kras-mutant non-small cell lung cancer. Cancer Immunology Research. PMID 30087114 DOI: 10.1158/2326-6066.Cir-18-0077 |
0.336 |
|
| 2018 |
Chatterji P, Hamilton KE, Liang S, Andres SF, Wijeratne HRS, Mizuno R, Simon LA, Hicks PD, Foley SW, Pitarresi JR, Klein-Szanto AJ, Mah AT, Van Landeghem L, Gregory BD, Lengner CJ, ... ... Rustgi AK, et al. The LIN28B-IMP1 post-transcriptional regulon has opposing effects on oncogenic signaling in the intestine. Genes & Development. 32: 1020-1034. PMID 30068703 DOI: 10.1101/Gad.314369.118 |
0.37 |
|
| 2018 |
Karakasheva TA, Lin EW, Tang Q, Qiao E, Waldron TJ, Soni M, Klein-Szanto AJ, Sahu V, Basu D, Ohashi S, Baba K, Giaccone ZT, Walker SR, Frank DA, Wileyto EP, ... ... Rustgi AK, et al. IL-6 mediates cross-talk between activated fibroblasts and tumor cells in the tumor microenvironment. Cancer Research. PMID 29976575 DOI: 10.1158/0008-5472.Can-17-2268 |
0.366 |
|
| 2018 |
Reichert M, Bakir B, Moreira L, Pitarresi JR, Feldmann K, Simon L, Suzuki K, Maddipati R, Rhim AD, Schlitter AM, Kriegsmann M, Weichert W, Wirth M, Schuck K, Schneider G, ... ... Rustgi AK, et al. Regulation of Epithelial Plasticity Determines Metastatic Organotropism in Pancreatic Cancer. Developmental Cell. 45: 696-711.e8. PMID 29920275 DOI: 10.1016/J.Devcel.2018.05.025 |
0.363 |
|
| 2018 |
Alvarez MJ, Subramaniam PS, Tang LH, Grunn A, Aburi M, Rieckhof G, Komissarova EV, Hagan EA, Bodei L, Clemons PA, Dela Cruz FS, Dhall D, Diolaiti D, Fraker DA, Ghavami A, ... ... Rustgi A, et al. A precision oncology approach to the pharmacological targeting of mechanistic dependencies in neuroendocrine tumors. Nature Genetics. PMID 29915428 DOI: 10.1038/S41588-018-0138-4 |
0.335 |
|
| 2018 |
Wong GS, Zhou J, Liu JB, Wu Z, Xu X, Li T, Xu D, Schumacher SE, Puschhof J, McFarland J, Zou C, Dulak A, Henderson L, Xu P, O'Day E, ... ... Rustgi AK, et al. Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition. Nature Medicine. PMID 29808010 DOI: 10.1038/S41591-018-0022-X |
0.372 |
|
| 2018 |
Giroux V, Stephan J, Chatterji P, Rhoades B, Wileyto EP, Klein-Szanto AJ, Lengner CJ, Hamilton KE, Rustgi AK. Mouse Intestinal Krt15+ Crypt Cells Are Radio-Resistant and Tumor Initiating. Stem Cell Reports. PMID 29805107 DOI: 10.1016/J.Stemcr.2018.04.022 |
0.362 |
|
| 2018 |
McKenna DB, Van Den Akker J, Zhou AY, Ryan L, Leon A, O'Connor R, Shah PD, Rustgi AK, Katona BW. Identification of a novel GREM1 duplication in a patient with multiple colon polyps. Familial Cancer. PMID 29804199 DOI: 10.1007/S10689-018-0090-6 |
0.309 |
|
| 2018 |
Tamura K, Yu J, Hata T, Suenaga M, Shindo K, Abe T, MacGregor-Das A, Borges M, Wolfgang CL, Weiss MJ, He J, Canto MI, Petersen GM, Gallinger S, Syngal S, ... ... Rustgi A, et al. Mutations in the pancreatic secretory enzymes and are associated with pancreatic cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 29669919 DOI: 10.1073/Pnas.1720588115 |
0.327 |
|
| 2018 |
Chatterji P, Rustgi AK. RNA Binding Proteins in Intestinal Epithelial Biology and Colorectal Cancer. Trends in Molecular Medicine. PMID 29627433 DOI: 10.1016/J.Molmed.2018.03.008 |
0.346 |
|
| 2018 |
Campbell JD, Yau C, Bowlby R, Liu Y, Brennan K, Fan H, Taylor AM, Wang C, Walter V, Akbani R, Byers LA, Creighton CJ, Coarfa C, Shih J, Cherniack AD, ... ... Rustgi AK, et al. Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas. Cell Reports. 23: 194-212.e6. PMID 29617660 DOI: 10.1016/J.Celrep.2018.03.063 |
0.34 |
|
| 2018 |
Karakasheva TA, Dominguez GA, Hashimoto A, Lin EW, Chiu C, Sasser K, Lee JW, Beatty GL, Gabrilovich DI, Rustgi AK. CD38+ M-MDSC expansion characterizes a subset of advanced colorectal cancer patients. Jci Insight. 3. PMID 29563330 DOI: 10.1172/Jci.Insight.97022 |
0.332 |
|
| 2018 |
Kasagi Y, Chandramouleeswaran PM, Whelan KA, Tanaka K, Giroux V, Sharma M, Wang J, Benitez AJ, DeMarshall M, Tobias JW, Hamilton KE, Falk GW, Spergel JM, Klein-Szanto AJ, Rustgi AK, et al. The Esophageal Organoid System Reveals Functional Interplay Between Notch and Cytokines in Reactive Epithelial Changes. Cellular and Molecular Gastroenterology and Hepatology. 5: 333-352. PMID 29552622 DOI: 10.1016/J.Jcmgh.2017.12.013 |
0.32 |
|
| 2018 |
Moreira L, Bakir B, Chatterji P, Dantes Z, Reichert M, Rustgi AK. Pancreas 3D Organoids: Current and Future Aspects as a Research Platform for Personalized Medicine in Pancreatic Cancer. Cellular and Molecular Gastroenterology and Hepatology. 5: 289-298. PMID 29541683 DOI: 10.1016/J.Jcmgh.2017.12.004 |
0.325 |
|
| 2018 |
Das KK, Heeg S, Pitarresi JR, Reichert M, Bakir B, Takano S, Kopp JL, Wahl-Feuerstein A, Hicks P, Sander M, Rustgi AK. ETV5 regulates ductal morphogenesis with Sox9 and is critical for regeneration from pancreatitis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 29532564 DOI: 10.1002/Dvdy.24626 |
0.338 |
|
| 2018 |
Facompre ND, Harmeyer KM, Sahu V, Gimotty PA, Rustgi AK, Nakagawa H, Basu D. Targeting JARID1B's demethylase activity blocks a subset of its functions in oral cancer. Oncotarget. 9: 8985-8998. PMID 29507668 DOI: 10.18632/Oncotarget.23739 |
0.396 |
|
| 2018 |
Mizuno R, Chatterji P, Andres SF, Hamilton KE, Simon L, Foley SW, Jeganathan AN, Gregory BD, Madison BB, Rustgi AK. Differential Regulation of LET-7 by LIN28B Isoform-specific Functions. Molecular Cancer Research : McR. PMID 29330293 DOI: 10.1158/1541-7786.Mcr-17-0514 |
0.34 |
|
| 2018 |
Perez K, Weekes CD, Cleary JM, Abrams TA, Blaszkowsky LS, Enzinger PC, Giannakis M, Goyal L, Meyerhardt JA, Rubinson DA, Yurgelun MB, Stonely D, Raghavan S, Bakir B, Das K, ... ... Rustgi A, et al. Phase Ib study of gemcitabine, nab-paclitaxel, and ficlatuzumab in patients with advanced pancreatic cancer. Journal of Clinical Oncology. 36: 693-693. DOI: 10.1200/Jco.2020.38.4_Suppl.693 |
0.33 |
|
| 2018 |
Pitarresi JR, Reichert M, Bakir B, Moreira L, Simon L, Rustgi AK. Abstract PR04: p120 catenin loss drives pancreatic cancer EMT and metastasis through activation of calcium signaling Cancer Research. 78. DOI: 10.1158/1538-7445.Mousemodels17-Pr04 |
0.426 |
|
| 2018 |
Adeegbe DO, Liu S, Bowden M, Hammerman PS, Bradner JE, Rustgi AK, Bass AJ, Freeman GJ, Chen H, Wong k. Abstract 4713: BET bromodomain inhibition synergizes with PD-1 blockade to facilitate anti-tumor response in Kras-mutant non-small cell lung cancer Cancer Research. 78: 4713-4713. DOI: 10.1158/1538-7445.Am2018-4713 |
0.35 |
|
| 2018 |
Andres SF, Williams KN, Hamilton KE, Mizuno R, Headd J, Chatterji P, Rustgi AK. Su1772 - The RNA Binding Protein Imp1 Enhances Colon Cancer Metastasis via Promotion of a Pro-Metastatic Gene Expression Program Gastroenterology. 154. DOI: 10.1016/S0016-5085(18)32135-8 |
0.333 |
|
| 2018 |
Abrams JA, Bokhari A, Compres G, Dalerba P, DeMarshall M, Falk GW, Friedman RA, Ginsberg GG, Iyer PG, Jin Z, Lightdale CJ, Lutzke LS, Nakagawa H, Nguyen T, Raab W, ... Rustgi AK, et al. Sa1657 - Increased Notch Signaling and Loss of Goblet Cell Differentiation with Progression from Barrett's Esophagus to Esophageal Adenocarcinoma: A Betrnet Study Gastroenterology. 154. DOI: 10.1016/S0016-5085(18)31481-1 |
0.333 |
|
| 2017 |
Natsuizaka M, Whelan KA, Kagawa S, Tanaka K, Giroux V, Chandramouleeswaran PM, Long A, Sahu V, Darling DS, Que J, Yang Y, Katz JP, Wileyto EP, Basu D, Kita Y, ... ... Rustgi AK, et al. Interplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma. Nature Communications. 8: 1758. PMID 29170450 DOI: 10.1038/S41467-017-01500-9 |
0.379 |
|
| 2017 |
Brown JC, Zemel BS, Troxel AB, Rickels MR, Damjanov N, Ky B, Rhim AD, Rustgi AK, Courneya KS, Schmitz KH. Dose-response effects of aerobic exercise on body composition among colon cancer survivors: a randomised controlled trial. British Journal of Cancer. PMID 28934762 DOI: 10.1038/Bjc.2017.339 |
0.302 |
|
| 2017 |
Giroux V, Rustgi AK. Metaplasia: tissue injury adaptation and a precursor to the dysplasia-cancer sequence. Nature Reviews. Cancer. PMID 28860646 DOI: 10.1038/Nrc.2017.68 |
0.402 |
|
| 2017 |
Lin EW, Karakasheva TA, Lee DJ, Lee JS, Long Q, Bass AJ, Wong KK, Rustgi AK. Comparative transcriptomes of adenocarcinomas and squamous cell carcinomas reveal molecular similarities that span classical anatomic boundaries. Plos Genetics. 13: e1006938. PMID 28787442 DOI: 10.1371/Journal.Pgen.1006938 |
0.399 |
|
| 2017 |
Laczkó D, Wang F, Johnson FB, Jhala N, Rosztóczy A, Ginsberg GG, Falk GW, Rustgi AK, Lynch JP. Modeling Esophagitis Using Human Three-Dimensional Organotypic Culture System. The American Journal of Pathology. PMID 28627413 DOI: 10.1016/J.Ajpath.2017.04.013 |
0.336 |
|
| 2017 |
Giroux V, Lento AA, Islam M, Pitarresi JR, Kharbanda A, Hamilton KE, Whelan KA, Long A, Rhoades B, Tang Q, Nakagawa H, Lengner CJ, Bass AJ, Wileyto EP, Klein-Szanto AJ, ... ... Rustgi AK, et al. Long-lived keratin 15+ esophageal progenitor cells contribute to homeostasis and regeneration. The Journal of Clinical Investigation. PMID 28481227 DOI: 10.1172/Jci88941 |
0.367 |
|
| 2017 |
Whelan KA, Chandramouleeswaran PM, Tanaka K, Natsuizaka M, Guha M, Srinivasan S, Darling DS, Kita Y, Natsugoe S, Winkler JD, Klein-Szanto AJ, Amaravadi RK, Avadhani NG, Rustgi AK, Nakagawa H. Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance. Oncogene. PMID 28414310 DOI: 10.1038/Onc.2017.102 |
0.327 |
|
| 2017 |
Zhang H, Fillmore Brainson C, Koyama S, Redig AJ, Chen T, Li S, Gupta M, Garcia-de-Alba C, Paschini M, Herter-Sprie GS, Lu G, Zhang X, Marsh BP, Tuminello SJ, Xu C, ... ... Rustgi AK, et al. Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2. Nature Communications. 8: 14922. PMID 28387316 DOI: 10.1038/Ncomms14922 |
0.317 |
|
| 2017 |
Yang TB, Chen Q, Deng JT, Jagannathan G, Tobias JW, Schultz DC, Wang S, Lengner CJ, Rustgi AK, Lynch JP, Johnson FB. Mutual reinforcement between telomere capping and canonical Wnt signalling in the intestinal stem cell niche. Nature Communications. 8: 14766. PMID 28303901 DOI: 10.1038/Ncomms14766 |
0.33 |
|
| 2017 |
Katona BW, Rustgi AK. Gastric Cancer Genomics: Advances and Future Directions. Cellular and Molecular Gastroenterology and Hepatology. 3: 211-217. PMID 28275688 DOI: 10.1016/J.Jcmgh.2017.01.003 |
0.318 |
|
| 2017 |
Katlinski KV, Gui J, Katlinskaya YV, Ortiz A, Chakraborty R, Bhattacharya S, Carbone CJ, Beiting DP, Girondo MA, Peck AR, Puré E, Chatterji P, Rustgi AK, Diehl JA, Koumenis C, et al. Inactivation of Interferon Receptor Promotes the Establishment of Immune Privileged Tumor Microenvironment. Cancer Cell. 31: 194-207. PMID 28196594 DOI: 10.1016/J.Ccell.2017.01.004 |
0.362 |
|
| 2017 |
Zhou J, Wu Z, Wong G, Pectasides E, Nagaraja A, Stachler M, Zhang H, Chen T, Zhang H, Liu JB, Xu X, Sicinska E, Sanchez-Vega F, Rustgi AK, Diehl JA, et al. CDK4/6 or MAPK blockade enhances efficacy of EGFR inhibition in oesophageal squamous cell carcinoma. Nature Communications. 8: 13897. PMID 28059068 DOI: 10.1038/Ncomms13897 |
0.304 |
|
| 2017 |
Marchand B, Reichert M, Collins MA, Rustgi AK. Abstract 5503: Interplay between the transcription factors PRRX1 and FOXM1 in pancreatic cancer Cancer Research. 77: 5503-5503. DOI: 10.1158/1538-7445.Am2017-5503 |
0.411 |
|
| 2017 |
Giroux V, Stephan J, Hamilton KE, Chatterjee P, Andres S, Klein-Szanto AJ, Lengner CJ, Rustgi AK. Abstract 5022: Keratin15 (Krt15) + are radio resistant and tumor-initiating cells in the mouse small intestine Cancer Research. 77: 5022-5022. DOI: 10.1158/1538-7445.Am2017-5022 |
0.323 |
|
| 2017 |
Lento A, Long A, Giroux V, Tang Q, Sammons M, Klein-Szanto A, Berger S, Rustgi A. Abstract 2578: Investigating the role of mutant p53 in esophageal squamous cell carcinoma Cancer Research. 77: 2578-2578. DOI: 10.1158/1538-7445.Am2017-2578 |
0.315 |
|
| 2017 |
Bakir B, Moreira L, Reichert M, Pitarresi J, Marchand B, Adsay VN, Rustgi AK. Differential P120CTN Isoform Regulation of Pancreatic Cancer Initiation and Metastasis Gastroenterology. 152. DOI: 10.1016/S0016-5085(17)31216-7 |
0.38 |
|
| 2017 |
Rivera CA, Dominguez GA, Tomov V, Falk GW, Ginsberg GG, Gabrilovich D, Rustgi AK, Lynch JP. Identification of Myeloid Derived Suppressor Cells in the Barrett’s Metaplasia to Esophageal Adenocarcinoma Sequence Gastroenterology. 152: S234. DOI: 10.1016/S0016-5085(17)31071-5 |
0.318 |
|
| 2017 |
Whelan KA, Tanaka K, Kijima T, Ohashi S, Chandramouleeswaran P, Sharma M, Kita Y, Klein-Szanto A, Ginsberg GG, Muto M, Natsugoe S, Rustgi AK, Nakagawa H. 3D Organoids Reveal the Autophagy-CD44 Cell Axis in Esophageal Cancer Therapy Resistance Gastroenterology. 152: S169. DOI: 10.1016/S0016-5085(17)30883-1 |
0.307 |
|
| 2016 |
Condamine T, Dominguez GA, Youn JI, Kossenkov AV, Mony S, Alicea-Torres K, Tcyganov E, Hashimoto A, Nefedova Y, Lin C, Partlova S, Garfall A, Vogl DT, Xu X, Knight SC, ... ... Rustgi A, et al. Lectin-type oxidized LDL receptor-1 distinguishes population of human polymorphonuclear myeloid-derived suppressor cells in cancer patients. Science Immunology. 1. PMID 28417112 DOI: 10.1126/Sciimmunol.Aaf8943 |
0.365 |
|
| 2016 |
Lizotte PH, Ivanova EV, Awad MM, Jones RE, Keogh L, Liu H, Dries R, Almonte C, Herter-Sprie GS, Santos A, Feeney NB, Paweletz CP, Kulkarni MM, Bass AJ, Rustgi AK, et al. Multiparametric profiling of non-small-cell lung cancers reveals distinct immunophenotypes. Jci Insight. 1: e89014. PMID 27699239 DOI: 10.1172/Jci.Insight.89014 |
0.364 |
|
| 2016 |
Rustgi AK. Pancreatic fibroblasts smoothen their activities via AKT-GLI2-TGFα. Genes & Development. 30: 1911-2. PMID 27664234 DOI: 10.1101/Gad.289272.116 |
0.363 |
|
| 2016 |
von Burstin J, Bachhuber F, Paul M, Schmid RM, Rustgi AK. The TALE homeodomain transcription factor MEIS1 activates the pro-metastatic melanoma cell adhesion molecule Mcam to promote migration of pancreatic cancer cells. Molecular Carcinogenesis. PMID 27583552 DOI: 10.1002/Mc.22547 |
0.44 |
|
| 2016 |
Facompre ND, Harmeyer KM, Sole X, Kabraji S, Belden Z, Sahu V, Whelan K, Tanaka K, Weinstein GS, Montone KT, Roesch A, Gimotty PA, Herlyn M, Rustgi AK, Nakagawa H, et al. JARID1B enables transit between distinct states of the stem-like cell population in oral cancers. Cancer Research. PMID 27488530 DOI: 10.1158/0008-5472.Can-15-3377 |
0.391 |
|
| 2016 |
Lee Y, Urbanska AM, Hayakawa Y, Wang H, Au AS, Luna AM, Chang W, Jin G, Bhagat G, Abrams JA, Friedman RA, Varro A, Wang KK, Boyce M, Rustgi AK, et al. Gastrin stimulates a cholecystokinin-2-receptor-expressing cardia progenitor cell and promotes progression of Barrett's-like esophagus. Oncotarget. PMID 27448962 DOI: 10.18632/Oncotarget.10667 |
0.319 |
|
| 2016 |
Chowdhury AR, Long A, Fuchs SY, Rustgi A, Avadhani NG. Mitochondrial stress-induced p53 attenuates HIF-1α activity by physical association and enhanced ubiquitination. Oncogene. PMID 27345397 DOI: 10.1038/Onc.2016.211 |
0.301 |
|
| 2016 |
Heeg S, Das KK, Reichert M, Bakir B, Takano S, Caspers J, Aiello NM, Wu K, Neesse A, Maitra A, Iacobuzio-Donahue CA, Hicks P, Rustgi AK. The ETS-Transcription Factor ETV1 Regulates Stromal Expansion and Metastasis in Pancreatic Cancer. Gastroenterology. PMID 27318148 DOI: 10.1053/J.Gastro.2016.06.005 |
0.364 |
|
| 2016 |
Dotto GP, Rustgi AK. Squamous Cell Cancers: A Unified Perspective on Biology and Genetics. Cancer Cell. 29: 622-37. PMID 27165741 DOI: 10.1016/J.Ccell.2016.04.004 |
0.408 |
|
| 2016 |
Westphalen CB, Takemoto Y, Tanaka T, Macchini M, Jiang Z, Renz BW, Chen X, Ormanns S, Nagar K, Tailor Y, May R, Cho Y, Asfaha S, Worthley DL, Hayakawa Y, ... ... Rustgi AK, et al. Dclk1 Defines Quiescent Pancreatic Progenitors that Promote Injury-Induced Regeneration and Tumorigenesis. Cell Stem Cell. 18: 441-455. PMID 27058937 DOI: 10.1016/J.Stem.2016.03.016 |
0.391 |
|
| 2016 |
Lin EW, Karakasheva TA, Hicks PD, Bass AJ, Rustgi AK. The tumor microenvironment in esophageal cancer. Oncogene. PMID 26923327 DOI: 10.1038/Onc.2016.34 |
0.423 |
|
| 2016 |
Takano S, Reichert M, Bakir B, Das KK, Nishida T, Miyazaki M, Heeg S, Collins MA, Marchand B, Hicks PD, Maitra A, Rustgi AK. Prrx1 isoform switching regulates pancreatic cancer invasion and metastatic colonization. Genes & Development. 30: 233-47. PMID 26773005 DOI: 10.1101/Gad.263327.115 |
0.383 |
|
| 2016 |
Westphalen CB, Renz B, Reichert M, Rustgi A, Wang TC. Cellular plasticity and heterogeneity in pancreatic regeneration and malignancy Cancer Cell & Microenvironment. 3. DOI: 10.14800/Ccm.1472 |
0.333 |
|
| 2016 |
Karakasheva T, Lin E, Hicks P, Waldron T, Rustgi AK. Abstract IA13: The interplay between tumor cells, cancer associated fibroblasts, and immature myeloid cells in the esophageal tumor microenvironment Cancer Research. 76. DOI: 10.1158/1538-7445.Tme16-Ia13 |
0.407 |
|
| 2016 |
Lin EW, Karakasheva TA, Derks S, Wong KK, Bass AJ, Rustgi AK. Abstract A37: The role of IL-6 in the interaction between fibroblasts and tumor cells in esophageal adenocarcinoma Cancer Research. 76. DOI: 10.1158/1538-7445.Tme16-A37 |
0.342 |
|
| 2016 |
Karakasheva TA, Soni M, Waldron TJ, Lin EW, Hicks PD, Klein-Szanto A, Wong KK, Bass AJ, Rustgi AK. Abstract A32: Il-6 initiates a self-sustaining signaling loop to promote nurturing tumor microenvironment Cancer Research. 76. DOI: 10.1158/1538-7445.Tme16-A32 |
0.39 |
|
| 2016 |
Takano S, Reichert M, Yoshitomi H, Bakir B, Das KK, Heeg S, Kagawa S, Shimizu H, Ohtsuka M, Furukawa K, Miyazaki M, Rustgi AK. Abstract B30: Prrx1 isoforms regulate pancreatic cancer stem cell functions during pancreatic cancer progression Cancer Research. 76. DOI: 10.1158/1538-7445.Panca16-B30 |
0.374 |
|
| 2016 |
Wang F, Laczkó D, Crissey MA, Falk G, Johnson B, Rustgi A, Lynch J. Abstract 4253: Modeling the effects of inflammatory stress on human intestinal epithelial cells in 3D enteroid co-culture system Cancer Research. 76: 4253-4253. DOI: 10.1158/1538-7445.Am2016-4253 |
0.353 |
|
| 2016 |
Chatterji P, Hamilton K, Andres S, Mizuno R, Hicks P, Jeganathan A, Winslow MM, Castells A, Cuatrecasas M, Madison B, Rustgi A. Abstract 1136: Cooperative functional roles of RNA binding proteins LIN28B and IMP1 in the pathogenesis of colorectal cancer Cancer Research. 76: 1136-1136. DOI: 10.1158/1538-7445.Am2016-1136 |
0.406 |
|
| 2016 |
Andres SF, Hamilton K, Chatterji P, Hicks PD, Rustgi AK. 467 Insulin-Like Growth Factor 2 mRNA Binding Protein 1 (IMP1)-Positive Cells in the Crypt Initiate Tumor Formation in the Small Intestinal and Colonic Epithelia Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)30452-8 |
0.321 |
|
| 2015 |
Ferreira MJ, McKenna LB, Zhang J, Reichert M, Bakir B, Buza EL, Furth EE, Bogue CW, Rustgi AK, Kaestner KH. Spontaneous Pancreatitis Caused by Tissue-Specific Gene Ablation of Hhex in Mice. Cellular and Molecular Gastroenterology and Hepatology. 1: 550-569. PMID 26740970 DOI: 10.1016/J.Jcmgh.2015.06.007 |
0.314 |
|
| 2015 |
Roberts NJ, Norris AL, Petersen GM, Bondy ML, Brand R, Gallinger S, Kurtz RC, Olson SH, Rustgi AK, Schwartz AG, Stoffel EM, Syngal S, Zogopoulos G, Ali SZ, Axilbund J, et al. Whole genome sequencing defines the genetic heterogeneity of familial pancreatic cancer. Cancer Discovery. PMID 26658419 DOI: 10.1158/2159-8290.Cd-15-0402 |
0.339 |
|
| 2015 |
Yang YX, Rustgi AK. Impact of Metformin on Advanced Pancreatic Cancer Survival: Too Little, Too Late? Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26637275 DOI: 10.1158/1078-0432.Ccr-15-2494 |
0.349 |
|
| 2015 |
Diersch S, Wirth M, Schneeweis C, Jörs S, Geisler F, Siveke JT, Rad R, Schmid RM, Saur D, Rustgi AK, Reichert M, Schneider G. Kras(G12D) induces EGFR-MYC cross signaling in murine primary pancreatic ductal epithelial cells. Oncogene. PMID 26592448 DOI: 10.1038/Onc.2015.437 |
0.35 |
|
| 2015 |
Sulahian R, Chen J, Arany Z, Jadhav U, Peng S, Rustgi AK, Bass AJ, Srivastava A, Hornick JL, Shivdasani RA. SOX15 governs transcription in human stratified epithelia and a subset of esophageal adenocarcinomas. Cellular and Molecular Gastroenterology and Hepatology. 1: 598-609.e6. PMID 26516633 DOI: 10.1016/J.Jcmgh.2015.07.009 |
0.355 |
|
| 2015 |
Schnepp RW, Khurana P, Attiyeh EF, Raman P, Chodosh SE, Oldridge DA, Gagliardi ME, Conkrite KL, Asgharzadeh S, Seeger RC, Madison BB, Rustgi AK, Maris JM, Diskin SJ. A LIN28B-RAN-AURKA Signaling Network Promotes Neuroblastoma Tumorigenesis. Cancer Cell. 28: 599-609. PMID 26481147 DOI: 10.1016/J.Ccell.2015.09.012 |
0.306 |
|
| 2015 |
Kong J, Whelan KA, Laczkó D, Dang B, Caro Monroig A, Soroush A, Falcone J, Amaravadi RK, Rustgi AK, Ginsberg GG, Falk GW, Nakagawa H, Lynch JP. Autophagy levels are elevated in barrett's esophagus and promote cell survival from acid and oxidative stress. Molecular Carcinogenesis. PMID 26373456 DOI: 10.1002/Mc.22406 |
0.328 |
|
| 2015 |
Karakasheva TA, Waldron TJ, Eruslanov E, Lee JS, O'Brien S, Hicks PD, Basu D, Singhal S, Malavasi F, Rustgi AK. CD38-Expressing Myeloid-Derived Suppressor Cells Promote Tumor Growth in a Murine Model of Esophageal Cancer. Cancer Research. PMID 26294209 DOI: 10.1158/0008-5472.Can-14-3639 |
0.343 |
|
| 2015 |
Madison BB, Jeganathan AN, Mizuno R, Winslow MM, Castells A, Cuatrecasas M, Rustgi AK. Let-7 Represses Carcinogenesis and a Stem Cell Phenotype in the Intestine via Regulation of Hmga2. Plos Genetics. 11: e1005408. PMID 26244988 DOI: 10.1371/Journal.Pgen.1005408 |
0.342 |
|
| 2015 |
Hamilton KE, Chatterji P, Lundsmith ET, Andres SF, Giroux V, Hicks PD, Noubissi FK, Spiegelman VS, Rustgi AK. Loss of Stromal Imp1 Promotes a Tumorigenic Microenvironment in the Colon. Molecular Cancer Research : McR. PMID 26194191 DOI: 10.1158/1541-7786.Mcr-15-0224 |
0.422 |
|
| 2015 |
Heidari P, Esfahani SA, Turker NS, Wong G, Wang TC, Rustgi AK, Mahmood U. Imaging of Secreted Extracellular Periostin, an Important Marker of Invasion in the Tumor Microenvironment in Esophageal Cancer. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 56: 1246-51. PMID 26069303 DOI: 10.2967/Jnumed.115.156216 |
0.372 |
|
| 2015 |
Asfaha S, Hayakawa Y, Muley A, Stokes S, Graham TA, Ericksen RE, Westphalen CB, von Burstin J, Mastracci TL, Worthley DL, Guha C, Quante M, Rustgi AK, Wang TC. Krt19(+)/Lgr5(-) Cells Are Radioresistant Cancer-Initiating Stem Cells in the Colon and Intestine. Cell Stem Cell. 16: 627-38. PMID 26046762 DOI: 10.1016/J.Stem.2015.04.013 |
0.379 |
|
| 2015 |
Rhim AD, Jechlinger M, Rustgi AK. Culturing mouse tumor cells. Cold Spring Harbor Protocols. 2015: 505-7. PMID 26034311 DOI: 10.1101/Pdb.Top069989 |
0.381 |
|
| 2015 |
Reichert M, Rhim AD, Rustgi AK. Culturing primary mouse pancreatic ductal cells. Cold Spring Harbor Protocols. 2015: 558-61. PMID 26034301 DOI: 10.1101/Pdb.Prot078279 |
0.38 |
|
| 2015 |
Hamilton KE, Crissey MA, Lynch JP, Rustgi AK. Culturing adult stem cells from mouse small intestinal crypts. Cold Spring Harbor Protocols. 2015: 354-8. PMID 25834260 DOI: 10.1101/Pdb.Prot078303 |
0.33 |
|
| 2015 |
Lian Z, Lee EK, Bass AJ, Wong KK, Klein-Szanto AJ, Rustgi AK, Diehl JA. FBXO4 loss facilitates carcinogen induced papilloma development in mice. Cancer Biology & Therapy. 16: 750-5. PMID 25801820 DOI: 10.1080/15384047.2015.1026512 |
0.317 |
|
| 2015 |
Long A, Giroux V, Whelan KA, Hamilton KE, Tétreault MP, Tanaka K, Lee JS, Klein-Szanto AJ, Nakagawa H, Rustgi AK. WNT10A promotes an invasive and self-renewing phenotype in esophageal squamous cell carcinoma. Carcinogenesis. 36: 598-606. PMID 25795715 DOI: 10.1093/Carcin/Bgv025 |
0.418 |
|
| 2015 |
von Burstin J, Diersch S, Schneider G, Reichert M, Rustgi AK, Schmid RM. Detection of Tumor Suppressor Genes in Cancer Development by a Novel shRNA-Based Method. Molecular Cancer Research : McR. 13: 863-9. PMID 25724428 DOI: 10.1158/1541-7786.Mcr-14-0709 |
0.405 |
|
| 2015 |
Li Y, Chitnis N, Nakagawa H, Kita Y, Natsugoe S, Yang Y, Li Z, Wasik M, Klein-Szanto AJ, Rustgi AK, Diehl JA. PRMT5 is required for lymphomagenesis triggered by multiple oncogenic drivers. Cancer Discovery. 5: 288-303. PMID 25582697 DOI: 10.1158/2159-8290.Cd-14-0625 |
0.379 |
|
| 2015 |
Reichert M, Bakir BS, Hahn CM, Botta GP, Rhim AD, Vonderheide RH, Reynolds AB, Bi Y, Davuluri R, Saka B, Adsay NV, Rustgi AK. Abstract PR05: p120 catenin mediated epithelial-to-mesenchymal plasticity determines the metastatic potential of pancreatic ductal adenocarcinoma Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-Pr05 |
0.363 |
|
| 2015 |
Das KK, Heeg S, Reichert M, Takano S, Bakir BS, Botta GP, Hahn C, Rhim AD, Rustgi AK. Abstract A46: The Ets-transcription factor Etv1 induces epithelial-mesenchymal transition (EMT) and invasion as well as expands the stromal compartment in vivo Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-A46 |
0.434 |
|
| 2015 |
Das KK, Heeg S, Reichert M, Takano S, Bakir BS, Botta GP, Hahn C, Rhim AD, Rustgi AK. Abstract A11: Ets transcription factor Etv5 regulates ductal morphogenesis and differentiation in association with Sox9 in vitro and increases susceptibility and delays recovery from pancreatitis in vivo Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-A11 |
0.391 |
|
| 2015 |
Natsuizaka M, Kagawa S, Whelan K, Ohashi S, Ohnishi S, Suda G, Sakamoto N, Rustgi AK, Nakagawa H. Abstract A74: TGF-β in tumor microenvironment changes a switch of Notch1-mediated signaling to maintain cancer stem-like cells in esophageal squamous cell carcinoma Cancer Research. 75. DOI: 10.1158/1538-7445.Chtme14-A74 |
0.391 |
|
| 2015 |
Schnepp RW, Khurana P, Attiyeh EF, Chodosh S, Raman P, Oldridge DA, Gagliardi ME, Conkrite K, Asgharzadeh S, Seeger RC, Madison B, Rustgi A, Maris JM, Diskin SJ. Abstract 4734: A LIN28B/RAN/AURKA signaling network promotes neuroblastoma tumorigenesis Cancer Research. 75: 4734-4734. DOI: 10.1158/1538-7445.Am2015-4734 |
0.379 |
|
| 2015 |
Karakasheva TA, Waldron TJ, Eruslanov E, Lee J, O'Brien S, Basu D, Singhal S, Malavasi F, Rustgi AK. Abstract 3175: CD38-expressing myeloid-derived suppressor cells promote tumor growth in a murine model of esophageal cancer Immunology. 75: 3175-3175. DOI: 10.1158/1538-7445.Am2015-3175 |
0.376 |
|
| 2015 |
Karakasheva TA, Soni M, Waldron T, Rustgi AK. Abstract 2383: IL-6 and RANTES mediate the cross-talk between tumor cells and CAFs in the esophageal tumor microenvironment Cancer Research. 75: 2383-2383. DOI: 10.1158/1538-7445.Am2015-2383 |
0.4 |
|
| 2015 |
Johnstone CN, Harris N, Ranson M, Rustgi AK, Anderson RL. Abstract 2251: Serglycin proteoglycan promotes progression and metastasis of triple-negative breast cancers Cancer Research. 75: 2251-2251. DOI: 10.1158/1538-7445.Am2015-2251 |
0.363 |
|
| 2015 |
Facompre N, Belden Z, Gimotty P, Rustgi A, Herlyn M, Nakagawa H, Basu D. Abstract 1517: G0-like cells support an oral cancer stem cell pool by transitioning to a JARID1B-high state Cancer Research. 75: 1517-1517. DOI: 10.1158/1538-7445.Am2015-1517 |
0.387 |
|
| 2015 |
Whelan KA, Kinugasa H, Tanaka K, Srinivasan S, Guha M, Clair DS, Klein-Szanto A, Avadhani N, Diehl A, Rustgi A, Nakagawa H. Abstract 1254: Mitochondrial SOD2 regulates EMT and cancer stem cell-like cell populations Cancer Research. 75: 1254-1254. DOI: 10.1158/1538-7445.Am2015-1254 |
0.354 |
|
| 2015 |
Long A, Zhu J, Giroux V, Berger SL, Rustgi AK, Nachamkin SI. 87: Mutant p53 Can Drive Cancer Initiation and Progression Through Gain-of-Function Properties American Journal of Clinical Pathology. 143. DOI: 10.1093/Ajcp/143.Suppl1.051 |
0.327 |
|
| 2015 |
Caspers J, Das KK, Wahl A, Rustgi AK, Heeg S. Tu2001 The ETS-Transcription Factor Etv1 Induces Stromal Expansion Through Activation of Hyaluron Synthase 2 (HAS2) in an Orthotopic Mouse Model of Pancreatic Cancer Gastroenterology. 148. DOI: 10.1016/S0016-5085(15)33267-4 |
0.342 |
|
| 2015 |
Whelan KA, Tanaka K, Kinugasa H, Natsuizaka M, Que J, Amaravadi RK, Klein-Szanto AJ, Diehl JA, Rustgi AK, Nakagawa H. Tu1997 Mitochondrial-Targeted Autophagy Promotes Cancer Stem Cell Expansion in ESCC Gastroenterology. 148: S-955. DOI: 10.1016/S0016-5085(15)33263-7 |
0.333 |
|
| 2015 |
Long A, Giroux V, Whelan KA, Klein-Szanto AJ, Nakagawa H, Rustgi AK. Su1961 Wnt10a Promotes a More Invasive and Self-Renewing Phenotype in Esophageal Squamous Cell Carcinoma Gastroenterology. 148: S-561. DOI: 10.1016/S0016-5085(15)31890-4 |
0.312 |
|
| 2014 |
Vega ME, Giroux V, Natsuizaka M, Liu M, Klein-Szanto AJ, Stairs DB, Nakagawa H, Wang KK, Wang TC, Lynch JP, Rustgi AK. Inhibition of Notch signaling enhances transdifferentiation of the esophageal squamous epithelium towards a Barrett's-like metaplasia via KLF4. Cell Cycle (Georgetown, Tex.). 13: 3857-66. PMID 25558829 DOI: 10.4161/15384101.2014.972875 |
0.686 |
|
| 2014 |
Kim J, Fox C, Peng S, Pusung M, Pectasides E, Matthee E, Hong YS, Do IG, Jang J, Thorner AR, Van Hummelen P, Rustgi AK, Wong KK, Zhou Z, Tang P, et al. Preexisting oncogenic events impact trastuzumab sensitivity in ERBB2-amplified gastroesophageal adenocarcinoma. The Journal of Clinical Investigation. 124: 5145-58. PMID 25401468 DOI: 10.1172/Jci75200 |
0.322 |
|
| 2014 |
Xu C, Fillmore CM, Koyama S, Wu H, Zhao Y, Chen Z, Herter-Sprie GS, Akbay EA, Tchaicha JH, Altabef A, Reibel JB, Walton Z, Ji H, Watanabe H, Jänne PA, ... ... Rustgi AK, et al. Loss of Lkb1 and Pten leads to lung squamous cell carcinoma with elevated PD-L1 expression. Cancer Cell. 25: 590-604. PMID 24794706 DOI: 10.1016/J.Ccr.2014.03.033 |
0.334 |
|
| 2014 |
Abrams JA, Appelman HD, Beer DG, Berry LD, Chak A, Falk GW, Fitzgerald RC, Ginsberg GG, Grady WM, Joshi BP, Lynch JP, Markowitz S, Richmond ES, Rustgi AK, Seibel EJ, et al. Barrett's Esophagus Translational Research Network (BETRNet): the pivotal role of multi-institutional collaboration in esophageal adenocarcinoma research. Gastroenterology. 146: 1586-90. PMID 24768332 DOI: 10.1053/J.Gastro.2014.04.014 |
0.31 |
|
| 2014 |
Watanabe H, Ma Q, Peng S, Adelmant G, Swain D, Song W, Fox C, Francis JM, Pedamallu CS, DeLuca DS, Brooks AN, Wang S, Que J, Rustgi AK, Wong KK, et al. SOX2 and p63 colocalize at genetic loci in squamous cell carcinomas. The Journal of Clinical Investigation. 124: 1636-45. PMID 24590290 DOI: 10.1172/Jci71545 |
0.377 |
|
| 2014 |
Rustgi AK. Familial pancreatic cancer: genetic advances. Genes & Development. 28: 1-7. PMID 24395243 DOI: 10.1101/Gad.228452.113 |
0.386 |
|
| 2014 |
Watanabe H, Ma Q, Peng S, Adelmant G, Swain D, Song W, Fox C, Francis JM, Pedamallu CS, Deluca DS, Brooks AN, Que J, Rustgi AK, Wong K, Ligon KL, et al. Abstract 1391: SOX2-p63 interaction and genomic co-localization in squamous cell carcinomas Cancer Research. 74: 1391-1391. DOI: 10.1158/1538-7445.Am2014-1391 |
0.381 |
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| 2014 |
Whelan KA, Kagawa S, Guo A, Natsuizaka M, Kinugasa H, Ohashi S, Kita Y, Natsugoe S, Naganuma S, Klein-Szanto AJ, Amaravadi RK, Rustgi AK, Nakagawa H. Tu1699 Autophagy Regulates Esophageal Cancer Stem Cell Phenotypic Plasticity by Targeting Mitochondria and Oxidative Stress Gastroenterology. 146: S-821. DOI: 10.1016/S0016-5085(14)62976-0 |
0.382 |
|
| 2014 |
Natsuizaka M, Kaimila B, Kubota Y, Hatanaka Y, Marukawa K, Terashita K, Satou F, Ohnishi S, Suda G, Ohashi S, Kagawa S, Whelan KA, Rustgi AK, Nakagawa H, Sakamoto N. Tu1698 EGFR Inhibitors Eliminate Esophageal Cancer Stem Cells by Suppressing Epithelial-Mesenchymal Transition Gastroenterology. 146: S-821. DOI: 10.1016/S0016-5085(14)62975-9 |
0.384 |
|
| 2014 |
Takano S, Reichert M, Heeg S, Bakir B, Das KK, Rhim AD, Yoshitomi H, Stanger B, Rustgi AK. Tu1665 Prrx1a and Prrx1b Differentially Regulate Invasion and Metastasis in Pancreatic Cancer Gastroenterology. 146: S-813. DOI: 10.1016/S0016-5085(14)62941-3 |
0.375 |
|
| 2013 |
Hartman KG, Bortner JD, Falk GW, Yu J, MartÃn MG, Rustgi AK, Lynch JP. Modeling inflammation and oxidative stress in gastrointestinal disease development using novel organotypic culture systems. Stem Cell Research & Therapy. 4: S5. PMID 24564965 DOI: 10.1186/Scrt366 |
0.309 |
|
| 2013 |
Madison BB, Liu Q, Zhong X, Hahn CM, Lin N, Emmett MJ, Stanger BZ, Lee JS, Rustgi AK. LIN28B promotes growth and tumorigenesis of the intestinal epithelium via Let-7. Genes & Development. 27: 2233-45. PMID 24142874 DOI: 10.1101/Gad.224659.113 |
0.34 |
|
| 2013 |
Rasanen K, Sriswasdi S, Valiga A, Tang HY, Zhang G, Perego M, Somasundaram R, Li L, Speicher K, Klein-Szanto AJ, Basu D, Rustgi AK, Speicher DW, Herlyn M. Comparative secretome analysis of epithelial and mesenchymal subpopulations of head and neck squamous cell carcinoma identifies S100A4 as a potential therapeutic target. Molecular & Cellular Proteomics : McP. 12: 3778-92. PMID 24037664 DOI: 10.1074/Mcp.M113.029587 |
0.421 |
|
| 2013 |
Basu D, Bewley AF, Sperry SM, Montone KT, Gimotty PA, Rasanen K, Facompre ND, Weinstein GS, Nakagawa H, Diehl JA, Rustgi AK, Herlyn M. EGFR inhibition promotes an aggressive invasion pattern mediated by mesenchymal-like tumor cells within squamous cell carcinomas. Molecular Cancer Therapeutics. 12: 2176-86. PMID 23939378 DOI: 10.1158/1535-7163.Mct-12-1210 |
0.39 |
|
| 2013 |
Rustgi AK. BRAF: a driver of the serrated pathway in colon cancer. Cancer Cell. 24: 1-2. PMID 23845435 DOI: 10.1016/J.Ccr.2013.06.008 |
0.37 |
|
| 2013 |
Grugan KD, Vega ME, Wong GS, Diehl JA, Bass AJ, Wong KK, Nakagawa H, Rustgi AK. A common p53 mutation (R175H) activates c-Met receptor tyrosine kinase to enhance tumor cell invasion. Cancer Biology & Therapy. 14: 853-9. PMID 23792586 DOI: 10.4161/Cbt.25406 |
0.688 |
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| 2013 |
Reichert M, Takano S, Heeg S, Bakir B, Botta GP, Rustgi AK. Isolation, culture and genetic manipulation of mouse pancreatic ductal cells. Nature Protocols. 8: 1354-65. PMID 23787893 DOI: 10.1038/Nprot.2013.079 |
0.391 |
|
| 2013 |
Hamilton KE, Noubissi FK, Katti PS, Hahn CM, Davey SR, Lundsmith ET, Klein-Szanto AJ, Rhim AD, Spiegelman VS, Rustgi AK. IMP1 promotes tumor growth, dissemination and a tumor-initiating cell phenotype in colorectal cancer cell xenografts. Carcinogenesis. 34: 2647-54. PMID 23764754 DOI: 10.1093/Carcin/Bgt217 |
0.421 |
|
| 2013 |
Waldron TJ, Quatromoni JG, Karakasheva TA, Singhal S, Rustgi AK. Myeloid derived suppressor cells: Targets for therapy. Oncoimmunology. 2: e24117. PMID 23734336 DOI: 10.4161/Onci.24117 |
0.332 |
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| 2013 |
Botta GP, Reichert M, Reginato MJ, Heeg S, Rustgi AK, Lelkes PI. ERK2-regulated TIMP1 induces hyperproliferation of K-Ras(G12D)-transformed pancreatic ductal cells. Neoplasia (New York, N.Y.). 15: 359-72. PMID 23555182 DOI: 10.1593/Neo.121708 |
0.334 |
|
| 2013 |
Liu K, Jiang M, Lu Y, Chen H, Sun J, Wu S, Ku WY, Nakagawa H, Kita Y, Natsugoe S, Peters JH, Rustgi A, Onaitis MW, Kiernan A, Chen X, et al. Sox2 cooperates with inflammation-mediated Stat3 activation in the malignant transformation of foregut basal progenitor cells. Cell Stem Cell. 12: 304-15. PMID 23472872 DOI: 10.1016/J.Stem.2013.01.007 |
0.385 |
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| 2013 |
Kadaba R, Birke H, Wang J, Hooper S, Andl CD, Di Maggio F, Soylu E, Ghallab M, Bor D, Froeling FE, Bhattacharya S, Rustgi AK, Sahai E, Chelala C, Sasieni P, et al. Imbalance of desmoplastic stromal cell numbers drives aggressive cancer processes. The Journal of Pathology. 230: 107-17. PMID 23359139 DOI: 10.1002/Path.4172 |
0.438 |
|
| 2013 |
Reichert M, Takano S, von Burstin J, Kim SB, Lee JS, Ihida-Stansbury K, Hahn C, Heeg S, Schneider G, Rhim AD, Stanger BZ, Rustgi AK. The Prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis. Genes & Development. 27: 288-300. PMID 23355395 DOI: 10.1101/Gad.204453.112 |
0.392 |
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| 2013 |
Wong GS, Rustgi AK. Matricellular proteins: priming the tumour microenvironment for cancer development and metastasis. British Journal of Cancer. 108: 755-61. PMID 23322204 DOI: 10.1038/Bjc.2012.592 |
0.305 |
|
| 2013 |
Morris JF, Sul JY, Kim MS, Klein-Szanto AJ, Schochet T, Rustgi A, Eberwine JH. Elk-1 phosphorylated at threonine-417 is present in diverse cancers and correlates with differentiation grade of colonic adenocarcinoma. Human Pathology. 44: 766-76. PMID 23114923 DOI: 10.1016/J.Humpath.2012.08.001 |
0.344 |
|
| 2013 |
Wong GS, Habibollahi P, Heidari P, Lee JS, Klein-Szanto AJ, Waldron TJ, Gimotty P, Nakagawa H, Taylor PR, Wang TC, Mahmood U, Rustgi AK. Optical imaging of periostin enables early endoscopic detection and characterization of esophageal cancer in mice. Gastroenterology. 144: 294-7. PMID 23085486 DOI: 10.1053/J.Gastro.2012.10.030 |
0.343 |
|
| 2013 |
Madison B, Liu Q, Zhong X, Hahn CM, Lin N, Emmet M, Stanger BZ, Rustgi AK. Abstract PR04: LIN28B promotes growth and tumorigenesis of the intestinal epithelium primarily via Let-7 repression Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-Pr04 |
0.42 |
|
| 2013 |
Hamilton KE, Katti PS, Hahn CM, Davey SR, Lundsmith ET, Rhim AD, Rustgi AK. Abstract 253: IMP1 mediates tumor size and dissemination into the blood in colorectal cancer cell xenografts. Cancer Research. 73: 253-253. DOI: 10.1158/1538-7445.Am2013-253 |
0.42 |
|
| 2013 |
Kagawa S, Nakagawa K, Natsuizaka M, Kinugasa H, Whelan KA, Chang S, Subramanian H, Ohashi S, Klein-Szanto AJ, Gimotty PA, Diehl JA, Herlyn M, Nakagawa H, Rustgi AK. 677 Inactivation of the Retinoblastoma Protein-Dependent Senescence Checkpoint Functions Permits Notch1 to Gain Oncogenic Tumor Promoting Activity Gastroenterology. 144: S-124. DOI: 10.1016/S0016-5085(13)60444-8 |
0.405 |
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| 2013 |
Takano S, Reichert M, Heeg S, Bakir B, Rhim AD, Stanger B, Rustgi AK. 339 The Prrx1 Homeobox Transcription Factor Regulates Invasion and EMT in Pancreatic Cancer Gastroenterology. 144: S-71. DOI: 10.1016/S0016-5085(13)60263-2 |
0.361 |
|
| 2013 |
Lukin DJ, Asfaha S, Westphalen CB, Rustgi AK, Wang TC. 281 Mutant K-RAS in the Epithelial Stem Cell Compartment Promotes Symmetric Stem Cell Division and Crypt Fission but Not Tumorigenesis in the Mouse Intestine and Colon Gastroenterology. 144: S-63. DOI: 10.1016/S0016-5085(13)60227-9 |
0.36 |
|
| 2013 |
Natsuizaka M, Kagawa S, Whelan KA, Chang S, Kinugasa H, Ohashi S, Naganuma S, Sakamoto N, Klein-Szanto AJ, Gimotty PA, Diehl JA, Herlyn M, Rustgi AK, Nakagawa H. 237 Transforming Growth Factor-β and Notch1 Cooperate to Repress NOTCH3 to Facilitate Epithelial-Mesenchymal Transition and Tumor Initiating Capability in Esophageal Squamous Cell Carcinoma Gastroenterology. 144: S-52. DOI: 10.1016/S0016-5085(13)60183-3 |
0.343 |
|
| 2012 |
Moreira L, Balaguer F, Lindor N, de la Chapelle A, Hampel H, Aaltonen LA, Hopper JL, Le Marchand L, Gallinger S, Newcomb PA, Haile R, Thibodeau SN, Gunawardena S, Jenkins MA, Buchanan DD, ... ... Rustgi AK, et al. Identification of Lynch syndrome among patients with colorectal cancer. Jama. 308: 1555-65. PMID 23073952 DOI: 10.1001/Jama.2012.13088 |
0.305 |
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| 2012 |
Ye Y, Madison B, Wu X, Rustgi AK. A LIN28B polymorphism predicts for colon cancer survival Cancer Biology and Therapy. 13: 1390-1395. PMID 23052130 DOI: 10.4161/Cbt.22336 |
0.348 |
|
| 2012 |
Tang W, Chowdhury AR, Guha M, Huang L, Van Winkle T, Rustgi AK, Avadhani NG. Silencing of IkBβ mRNA causes disruption of mitochondrial retrograde signaling and suppression of tumor growth in vivo. Carcinogenesis. 33: 1762-8. PMID 22637744 DOI: 10.1093/Carcin/Bgs190 |
0.355 |
|
| 2012 |
Rhim AD, Mirek ET, Aiello NM, Maitra A, Bailey JM, McAllister F, Reichert M, Beatty GL, Rustgi AK, Vonderheide RH, Leach SD, Stanger BZ. EMT and dissemination precede pancreatic tumor formation. Cell. 148: 349-61. PMID 22265420 DOI: 10.1016/J.Cell.2011.11.025 |
0.411 |
|
| 2012 |
Quante M, Bhagat G, Abrams JA, Marache F, Good P, Lee MD, Lee Y, Friedman R, Asfaha S, Dubeykovskaya Z, Mahmood U, Figueiredo JL, Kitajewski J, Shawber C, Lightdale CJ, ... Rustgi AK, et al. Bile acid and inflammation activate gastric cardia stem cells in a mouse model of Barrett-like metaplasia. Cancer Cell. 21: 36-51. PMID 22264787 DOI: 10.1016/J.Ccr.2011.12.004 |
0.312 |
|
| 2012 |
Kalabis J, Wong GS, Vega ME, Natsuizaka M, Robertson ES, Herlyn M, Nakagawa H, Rustgi AK. Isolation and characterization of mouse and human esophageal epithelial cells in 3D organotypic culture. Nature Protocols. 7: 235-46. PMID 22240585 DOI: 10.1038/Nprot.2011.437 |
0.669 |
|
| 2012 |
Botta GP, Reginato MJ, Reichert M, Rustgi AK, Lelkes PI. Constitutive K-RasG12D activation of ERK2 specifically regulates 3D invasion of human pancreatic cancer cells via MMP-1. Molecular Cancer Research : McR. 10: 183-96. PMID 22160930 DOI: 10.1158/1541-7786.Mcr-11-0399 |
0.338 |
|
| 2012 |
Patel ZS, Grugan KD, Rustgi AK, Cucinotta FA, Huff JL. Ionizing radiation enhances esophageal epithelial cell migration and invasion through a paracrine mechanism involving stromal-derived hepatocyte growth factor. Radiation Research. 177: 200-8. PMID 22077339 DOI: 10.1667/Rr2790.1 |
0.382 |
|
| 2012 |
Kosoff RE, Gardiner KL, Merlo LM, Pavlov K, Rustgi AK, Maley CC. Development and characterization of an organotypic model of Barrett's esophagus. Journal of Cellular Physiology. 227: 2654-9. PMID 21882191 DOI: 10.1002/Jcp.23007 |
0.339 |
|
| 2012 |
Reichert M, Rustgi AK, Takano S, Burstin JAv, Heeg S, Botta GP, Lee J, Schneider G, Rhim AD, Stanger BZ. Abstract A71: The Prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-A71 |
0.42 |
|
| 2012 |
Asfaha S, Westphalen CB, Ericksen R, Burstin Jv, Stokes S, Mastracci T, Quante M, Shibata W, Rustgi A, Wang TC. Abstract 3301: Multiple cytokeratin-19 positive stem cells contribute to the clonal origin of colonic tumors in mice Cancer Research. 72: 3301-3301. DOI: 10.1158/1538-7445.Am2012-3301 |
0.344 |
|
| 2012 |
Rhim AD, Reichert M, Rustgi AK, Stanger B. Mo1189 Inflammation is Sufficient and Required to Elicit EMT, Invasion and Dissemination of Pancreas Cells in a Genetically Engineered Mouse Model of Pancreatic Intraepithelial Neoplasia (PanIN) Gastroenterology. 142: S-617. DOI: 10.1016/S0016-5085(12)62369-5 |
0.34 |
|
| 2012 |
Asfaha S, Westphalen CB, Ericksen R, Burstin Jv, Stokes SC, Mastracci TL, Quante M, Shibata W, Worthley DL, Rustgi AK, Wang TC. Sa1772 Intestinal Isthmus Keratin-19 Positive Stem Cells Contribute to Intestinal Tumors Gastroenterology. 142. DOI: 10.1016/S0016-5085(12)61209-8 |
0.324 |
|
| 2011 |
Reichert M, Rustgi AK. Pancreatic ductal cells in development, regeneration, and neoplasia. The Journal of Clinical Investigation. 121: 4572-8. PMID 22133881 DOI: 10.1172/Jci57131 |
0.367 |
|
| 2011 |
Vaites LP, Lee EK, Lian Z, Barbash O, Roy D, Wasik M, Klein-Szanto AJ, Rustgi AK, Diehl JA. The Fbx4 tumor suppressor regulates cyclin D1 accumulation and prevents neoplastic transformation. Molecular and Cellular Biology. 31: 4513-23. PMID 21911473 DOI: 10.1128/Mcb.05733-11 |
0.358 |
|
| 2011 |
Predina JD, Judy B, Aliperti LA, Fridlender ZG, Blouin A, Kapoor V, Laguna B, Nakagawa H, Rustgi AK, Aguilar L, Aguilar-Cordova E, Albelda SM, Singhal S. Neoadjuvant in situ gene-mediated cytotoxic immunotherapy improves postoperative outcomes in novel syngeneic esophageal carcinoma models. Cancer Gene Therapy. 18: 871-83. PMID 21869822 DOI: 10.1038/Cgt.2011.56 |
0.352 |
|
| 2011 |
Weber SM, Bornstein S, Li Y, Malkoski SP, Wang D, Rustgi AK, Kulesz-Martin MF, Wang XJ, Lu SL. Tobacco-specific carcinogen nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induces AKT activation in head and neck epithelia. International Journal of Oncology. 39: 1193-8. PMID 21822536 DOI: 10.3892/Ijo.2011.1149 |
0.332 |
|
| 2011 |
King CE, Wang L, Winograd R, Madison BB, Mongroo PS, Johnstone CN, Rustgi AK. LIN28B fosters colon cancer migration, invasion and transformation through let-7-dependent and -independent mechanisms. Oncogene. 30: 4185-93. PMID 21625210 DOI: 10.1038/Onc.2011.131 |
0.646 |
|
| 2011 |
Basu D, Montone KT, Wang LP, Gimotty PA, Hammond R, Diehl JA, Rustgi AK, Lee JT, Rasanen K, Weinstein GS, Herlyn M. Detecting and targeting mesenchymal-like subpopulations within squamous cell carcinomas. Cell Cycle (Georgetown, Tex.). 10: 2008-16. PMID 21558812 DOI: 10.4161/Cc.10.12.15883 |
0.377 |
|
| 2011 |
Helland Ã…, Anglesio MS, George J, Cowin PA, Johnstone CN, House CM, Sheppard KE, Etemadmoghadam D, Melnyk N, Rustgi AK, Phillips WA, Johnsen H, Holm R, Kristensen GB, Birrer MJ, et al. Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers. Plos One. 6: e18064. PMID 21533284 DOI: 10.1371/Journal.Pone.0018064 |
0.368 |
|
| 2011 |
King CE, Cuatrecasas M, Castells A, Sepulveda AR, Lee JS, Rustgi AK. LIN28B promotes colon cancer progression and metastasis. Cancer Research. 71: 4260-8. PMID 21512136 DOI: 10.1158/0008-5472.Can-10-4637 |
0.63 |
|
| 2011 |
Stairs DB, Bayne LJ, Rhoades B, Vega ME, Waldron TJ, Kalabis J, Klein-Szanto A, Lee JS, Katz JP, Diehl JA, Reynolds AB, Vonderheide RH, Rustgi AK. Deletion of p120-catenin results in a tumor microenvironment with inflammation and cancer that establishes it as a tumor suppressor gene. Cancer Cell. 19: 470-83. PMID 21481789 DOI: 10.1016/J.Ccr.2011.02.007 |
0.678 |
|
| 2011 |
Mongroo PS, Noubissi FK, Cuatrecasas M, Kalabis J, King CE, Johnstone CN, Bowser MJ, Castells A, Spiegelman VS, Rustgi AK. IMP-1 displays cross-talk with K-Ras and modulates colon cancer cell survival through the novel proapoptotic protein CYFIP2. Cancer Research. 71: 2172-82. PMID 21252116 DOI: 10.1158/0008-5472.Can-10-3295 |
0.601 |
|
| 2011 |
Pinho AV, Rooman I, Reichert M, De Medts N, Bouwens L, Rustgi AK, Real FX. Adult pancreatic acinar cells dedifferentiate to an embryonic progenitor phenotype with concomitant activation of a senescence programme that is present in chronic pancreatitis. Gut. 60: 958-66. PMID 21193456 DOI: 10.1136/Gut.2010.225920 |
0.371 |
|
| 2011 |
Asfaha S, Ericksen R, Burstin Jv, Quante M, Shibata W, Rustgi AK, Wang TC. Abstract 5186: Lineage tracing of Cytokeratin 19 labels gastric, intestinal and colonic stem cells Cancer Research. 71: 5186-5186. DOI: 10.1158/1538-7445.Am2011-5186 |
0.37 |
|
| 2011 |
Stairs DB, Bayne LJ, Rhoades B, Vega ME, Nakagawa H, Klein-Szanto AJ, Katz JP, Reynolds AB, Vonderheide RH, Rustgi AK. Loss of P120-Catenin Results in Esophageal Tumorigenesis, Involving the Recruitment of Immature Myeloid Cells to the Tumor Microenvironment Gastroenterology. 140: S-182. DOI: 10.1016/S0016-5085(11)60735-X |
0.678 |
|
| 2010 |
Al-Adsani A, Burke ZD, Eberhard D, Lawrence KL, Shen CN, Rustgi AK, Sakaue H, Farrant JM, Tosh D. Dexamethasone treatment induces the reprogramming of pancreatic acinar cells to hepatocytes and ductal cells. Plos One. 5: e13650. PMID 21048969 DOI: 10.1371/Journal.Pone.0013650 |
0.373 |
|
| 2010 |
Okumura T, Ericksen RE, Takaishi S, Wang SS, Dubeykovskiy Z, Shibata W, Betz KS, Muthupalani S, Rogers AB, Fox JG, Rustgi AK, Wang TC. K-ras mutation targeted to gastric tissue progenitor cells results in chronic inflammation, an altered microenvironment, and progression to intraepithelial neoplasia. Cancer Research. 70: 8435-45. PMID 20959488 DOI: 10.1158/0008-5472.Can-10-1506 |
0.325 |
|
| 2010 |
Aggarwal P, Vaites LP, Kim JK, Mellert H, Gurung B, Nakagawa H, Herlyn M, Hua X, Rustgi AK, McMahon SB, Diehl JA. Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase. Cancer Cell. 18: 329-40. PMID 20951943 DOI: 10.1016/J.Ccr.2010.08.012 |
0.32 |
|
| 2010 |
von Burstin J, Reichert M, Wescott MP, Rustgi AK. The pancreatic and duodenal homeobox protein PDX-1 regulates the ductal specific keratin 19 through the degradation of MEIS1 and DNA binding. Plos One. 5: e12311. PMID 20808819 DOI: 10.1371/Journal.Pone.0012311 |
0.339 |
|
| 2010 |
Kashyap MK, Harsha HC, Renuse S, Pawar H, Sahasrabuddhe NA, Kim MS, Marimuthu A, Keerthikumar S, Muthusamy B, Kandasamy K, Subbannayya Y, Prasad TS, Mahmood R, Chaerkady R, Meltzer SJ, ... ... Rustgi AK, et al. SILAC-based quantitative proteomic approach to identify potential biomarkers from the esophageal squamous cell carcinoma secretome. Cancer Biology & Therapy. 10: 796-810. PMID 20686364 DOI: 10.4161/Cbt.10.8.12914 |
0.316 |
|
| 2010 |
Mongroo PS, Rustgi AK. The role of the miR-200 family in epithelial-mesenchymal transition. Cancer Biology & Therapy. 10: 219-22. PMID 20592490 DOI: 10.4161/Cbt.10.3.12548 |
0.341 |
|
| 2010 |
Andl CD, McCowan KM, Allison GL, Rustgi AK. Cathepsin B is the driving force of esophageal cell invasion in a fibroblast-dependent manner. Neoplasia (New York, N.Y.). 12: 485-98. PMID 20563251 DOI: 10.1593/Neo.10216 |
0.347 |
|
| 2010 |
Grugan KD, Miller CG, Yao Y, Michaylira CZ, Ohashi S, Klein-Szanto AJ, Diehl JA, Herlyn M, Han M, Nakagawa H, Rustgi AK. Fibroblast-secreted hepatocyte growth factor plays a functional role in esophageal squamous cell carcinoma invasion. Proceedings of the National Academy of Sciences of the United States of America. 107: 11026-31. PMID 20534479 DOI: 10.1073/Pnas.0914295107 |
0.423 |
|
| 2010 |
Michaylira CZ, Wong GS, Miller CG, Gutierrez CM, Nakagawa H, Hammond R, Klein-Szanto AJ, Lee JS, Kim SB, Herlyn M, Diehl JA, Gimotty P, Rustgi AK. Periostin, a cell adhesion molecule, facilitates invasion in the tumor microenvironment and annotates a novel tumor-invasive signature in esophageal cancer. Cancer Research. 70: 5281-92. PMID 20516120 DOI: 10.1158/0008-5472.Can-10-0704 |
0.427 |
|
| 2010 |
Basu D, Nguyen TT, Montone KT, Zhang G, Wang LP, Diehl JA, Rustgi AK, Lee JT, Weinstein GS, Herlyn M. Evidence for mesenchymal-like sub-populations within squamous cell carcinomas possessing chemoresistance and phenotypic plasticity. Oncogene. 29: 4170-82. PMID 20498638 DOI: 10.1038/Onc.2010.170 |
0.363 |
|
| 2010 |
Hanlon L, Avila JL, Demarest RM, Troutman S, Allen M, Ratti F, Rustgi AK, Stanger BZ, Radtke F, Adsay V, Long F, Capobianco AJ, Kissil JL. Notch1 functions as a tumor suppressor in a model of K-ras-induced pancreatic ductal adenocarcinoma. Cancer Research. 70: 4280-6. PMID 20484026 DOI: 10.1158/0008-5472.Can-09-4645 |
0.337 |
|
| 2010 |
Goicoechea SM, Bednarski B, Stack C, Cowan DW, Volmar K, Thorne L, Cukierman E, Rustgi AK, Brentnall T, Hwang RF, McCulloch CA, Yeh JJ, Bentrem DJ, Hochwald SN, Hingorani SR, et al. Isoform-specific upregulation of palladin in human and murine pancreas tumors. Plos One. 5: e10347. PMID 20436683 DOI: 10.1371/Journal.Pone.0010347 |
0.393 |
|
| 2010 |
Ohashi S, Natsuizaka M, Wong GS, Michaylira CZ, Grugan KD, Stairs DB, Kalabis J, Vega ME, Kalman RA, Nakagawa M, Klein-Szanto AJ, Herlyn M, Diehl JA, Rustgi AK, Nakagawa H. Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors. Cancer Research. 70: 4174-84. PMID 20424117 DOI: 10.1158/0008-5472.CAN-09-4614 |
0.646 |
|
| 2010 |
Yang VW, Lewis J, Wang TC, Rustgi AK. Colon cancer: an update and future directions. Gastroenterology. 138: 2027-8. PMID 20226784 DOI: 10.1053/J.Gastro.2010.03.007 |
0.336 |
|
| 2010 |
Beroukhim R, Mermel CH, Porter D, Wei G, Raychaudhuri S, Donovan J, Barretina J, Boehm JS, Dobson J, Urashima M, Mc Henry KT, Pinchback RM, Ligon AH, Cho YJ, Haery L, ... ... Rustgi AK, et al. The landscape of somatic copy-number alteration across human cancers. Nature. 463: 899-905. PMID 20164920 DOI: 10.1038/Nature08822 |
0.36 |
|
| 2010 |
Rustgi AK, Stairs DB, Grugan KD, Wong GS, Vega ME, Kalabis J, Nakagawa H, Gimotty PA, Klein-Szanto AJ, Diehl JA, Herlyn M. Abstract CN04-03: Esophageal cancer and the tumor microenvironment Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-09-Cn04-03 |
0.713 |
|
| 2010 |
Grugan KD, Miller CG, Michaylira CZ, Klein-Szanto AJ, Nakagawa H, Rustgi AK. Abstract 279: Increased Met receptor activation mediates enhanced cell invasion upon mutant p53 expression in esophageal squamous cell carcinoma Cancer Research. 70: 279-279. DOI: 10.1158/1538-7445.Am10-279 |
0.408 |
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| 2010 |
Stairs D, Bayne LJ, Rhoades B, Mui KL, Kalabis J, Nakagawa H, Wong GS, Grugan KD, Klein-Szanto AJ, Lee J, Katz JP, Vonderheide RH, Reynolds AB, Rustgi AK. 847g Inactivation of the P120-Catenin Gene Results in a Tumor Microenvironment With Inflammation and Cancer That Establishes Its Identity as a Bone Fide Tumor Suppressor Gastroenterology. 138: S-112. DOI: 10.1016/S0016-5085(10)60513-6 |
0.329 |
|
| 2010 |
Rhim AD, Rustgi AK, Stanger B. 406 Paracrine Hedgehog Activation in Myofibroblasts Leads to Reciprocal Dedifferentiation and Proliferation of Pancreatic Intraepithelial Neoplasia (PanIN) Epithelial Cells: Insight Into the Role of Stromal-Epithelial Interactions in Cancer Progression Gastroenterology. 138: S-60. DOI: 10.1016/S0016-5085(10)60274-0 |
0.411 |
|
| 2010 |
Nakagawa M, Ohashi S, Natsuizaka M, Vega ME, Stairs D, Klein-Szanto AJ, Diehl JA, Pear WS, Nakagawa H, Rustgi AK. 184 Cyclin D1 and EGFR Promote Invasive Growth of Human Esophageal Epithelial Cells in Concert With Impaired Notch Signaling Gastroenterology. 138: S-34. DOI: 10.1016/S0016-5085(10)60155-2 |
0.674 |
|
| 2009 |
Bass AJ, Watanabe H, Mermel CH, Yu S, Perner S, Verhaak RG, Kim SY, Wardwell L, Tamayo P, Gat-Viks I, Ramos AH, Woo MS, Weir BA, Getz G, Beroukhim R, ... ... Rustgi AK, et al. SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas. Nature Genetics. 41: 1238-42. PMID 19801978 DOI: 10.1038/Ng.465 |
0.402 |
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| 2009 |
Wescott MP, Rovira M, Reichert M, von Burstin J, Means A, Leach SD, Rustgi AK. Pancreatic ductal morphogenesis and the Pdx1 homeodomain transcription factor. Molecular Biology of the Cell. 20: 4838-44. PMID 19793922 DOI: 10.1091/Mbc.E09-03-0203 |
0.382 |
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| 2009 |
Rangiah K, Tippornwong M, Sangar V, Austin D, Tétreault MP, Rustgi AK, Blair IA, Yu KH. Differential secreted proteome approach in murine model for candidate biomarker discovery in colon cancer. Journal of Proteome Research. 8: 5153-64. PMID 19769411 DOI: 10.1021/Pr900518V |
0.351 |
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| 2009 |
Oliver-Krasinski JM, Kasner MT, Yang J, Crutchlow MF, Rustgi AK, Kaestner KH, Stoffers DA. The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice. The Journal of Clinical Investigation. 119: 1888-98. PMID 19487809 DOI: 10.1172/Jci37028 |
0.34 |
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| 2009 |
Wilkey JF, Buchberger G, Saucier K, Patel SM, Eisenberg E, Nakagawa H, Michaylira CZ, Rustgi AK, Mallya SM. Cyclin D1 overexpression increases susceptibility to 4-nitroquinoline-1-oxide-induced dysplasia and neoplasia in murine squamous oral epithelium. Molecular Carcinogenesis. 48: 853-61. PMID 19263437 DOI: 10.1002/Mc.20531 |
0.32 |
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| 2009 |
Vakoc CR, Wen YY, Gibbs RA, Johnstone CN, Rustgi AK, Blobel GA. Low frequency of MLL3 mutations in colorectal carcinoma. Cancer Genetics and Cytogenetics. 189: 140-1. PMID 19215798 DOI: 10.1016/J.Cancergencyto.2008.10.014 |
0.325 |
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| 2009 |
Yu KH, Barry CG, Austin D, Busch CM, Sangar V, Rustgi AK, Blair IA. Stable isotope dilution multidimensional liquid chromatography-tandem mass spectrometry for pancreatic cancer serum biomarker discovery. Journal of Proteome Research. 8: 1565-76. PMID 19199705 DOI: 10.1021/Pr800904Z |
0.309 |
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| 2009 |
Kong J, Nakagawa H, Isariyawongse BK, Funakoshi S, Silberg DG, Rustgi AK, Lynch JP. Induction of intestinalization in human esophageal keratinocytes is a multistep process. Carcinogenesis. 30: 122-30. PMID 18845559 DOI: 10.1093/Carcin/Bgn227 |
0.406 |
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| 2009 |
Basu D, Nguyen T, Montone K, Zhang G, Wang LP, Rustgi A, Lee J, Weinstein G, Herlyn M. Abstract C77: A mesenchymal‐like subpopulation within squamous cell carcinomas with chemotherapy resistance and phenotypic plasticity Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-C77 |
0.361 |
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| 2009 |
Nakagawa M, Wong G, Ohashi S, Natsuizaka M, Vega ME, Stairs DB, Rustgi AK. Abstract B11: Cyclin D1 overexpression antagonizes Notch inhibition in the esophageal squamous epithelium Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-B11 |
0.703 |
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| 2009 |
Ohashi S, Natsuizaka M, Wong G, Grugan KD, Kalabis J, Rustgi AK, Nakagawa H. Abstract A3: Facilitating epithelial to mesenchymal transition through inhibition of senescence checkpoint functions Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-A3 |
0.367 |
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| 2009 |
Stairs DB, Kalabis J, Rhoades B, Grugan KD, Nakagawa H, Wong G, Klein-Szanto AJ, Katz JP, Reynolds AB, Rustgi AK. 543 P120ctn Functions As a Bona Fide Tumor Suppressor Gene in Esophageal Cancer Gastroenterology. 136: A-84. DOI: 10.1016/S0016-5085(09)60378-4 |
0.352 |
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| 2009 |
Lim DM, Lombardi LA, Michaylira CZ, Rustgi AK, Wang M. 179 Functional Characterization of Toll-Like Receptor 3 Signaling in Human Esophageal Keratinocytes Gastroenterology. 136. DOI: 10.1016/S0016-5085(09)60150-5 |
0.38 |
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| 2009 |
Burstin Jv, Scott S, Reichert M, Wescott MP, Leach SD, Rustgi AK. 161 A Novel Mouse Model, K19CreERT2; Rosa26R, for the Selective and Specific Marking of Pancreatic Ductal Epithelial Cells Gastroenterology. 136. DOI: 10.1016/S0016-5085(09)60144-X |
0.339 |
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| 2008 |
Wescott MP, Rustgi AK. Pancreatic cancer: translating lessons from mouse models and hereditary syndromes. Cancer Prevention Research (Philadelphia, Pa.). 1: 503-6. PMID 19138999 DOI: 10.1158/1940-6207.Capr-08-0195 |
0.351 |
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| 2008 |
Kalabis J, Oyama K, Okawa T, Nakagawa H, Michaylira CZ, Stairs DB, Figueiredo JL, Mahmood U, Diehl JA, Herlyn M, Rustgi AK. A subpopulation of mouse esophageal basal cells has properties of stem cells with the capacity for self-renewal and lineage specification. The Journal of Clinical Investigation. 118: 3860-9. PMID 19033657 DOI: 10.1172/Jci35012 |
0.346 |
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| 2008 |
Harada H, Nakagawa H, Takaoka M, Lee J, Herlyn M, Diehl JA, Rustgi AK. Cleavage of MCM2 licensing protein fosters senescence in human keratinocytes. Cell Cycle (Georgetown, Tex.). 7: 3534-8. PMID 19001876 DOI: 10.4161/Cc.7.22.7043 |
0.364 |
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| 2008 |
Kalabis J, Li G, Fukunaga-Kalabis M, Rustgi AK, Herlyn M. Endothelin-3 stimulates survival of goblet cells in organotypic cultures of fetal human colonic epithelium American Journal of Physiology - Gastrointestinal and Liver Physiology. 295. PMID 18832450 DOI: 10.1152/Ajpgi.90294.2008 |
0.37 |
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| 2008 |
Lioni M, Noma K, Snyder A, Klein-Szanto A, Diehl JA, Rustgi AK, Herlyn M, Smalley KS. Bortezomib induces apoptosis in esophageal squamous cell carcinoma cells through activation of the p38 mitogen-activated protein kinase pathway. Molecular Cancer Therapeutics. 7: 2866-75. PMID 18790767 DOI: 10.1158/1535-7163.Mct-08-0391 |
0.318 |
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| 2008 |
Barbash O, Zamfirova P, Lin DI, Chen X, Yang K, Nakagawa H, Lu F, Rustgi AK, Diehl JA. Mutations in Fbx4 inhibit dimerization of the SCF(Fbx4) ligase and contribute to cyclin D1 overexpression in human cancer. Cancer Cell. 14: 68-78. PMID 18598945 DOI: 10.1016/J.Ccr.2008.05.017 |
0.362 |
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| 2008 |
Johnstone CN, Mongroo PS, Rich AS, Schupp M, Bowser MJ, Delemos AS, Tobias JW, Liu Y, Hannigan GE, Rustgi AK. Parvin-beta inhibits breast cancer tumorigenicity and promotes CDK9-mediated peroxisome proliferator-activated receptor gamma 1 phosphorylation. Molecular and Cellular Biology. 28: 687-704. PMID 17998334 DOI: 10.1128/Mcb.01617-06 |
0.333 |
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| 2008 |
Wescott MP, Burstin Jv, Deramaudt TB, Leach SD, Rustgi AK. T1900 Hepatocyte Growth Factor in Concert with PDX-1 Homeodomain Transcription Factor Regulate Pancreatic Ductal Cell Branching Morphogenesis Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)62742-0 |
0.301 |
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| 2008 |
Burstin Jv, Wescott MP, Deramaudt TB, Rustgi AK. T1899 The Meis Tale Transcription Factor Regulates K19 Gene Transcription in Pancreatic Ductal Epithelial Cells Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)62741-9 |
0.314 |
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| 2008 |
Yang Y, Stairs DB, Michaylira CZ, Lee JJ, Kalabis J, Grugan KD, Andl CD, Budo D, Pear WS, Katz JP, Rustgi AK, Nakagawa H. M2010 Notch Signaling Regulates Esophageal Epithelial Homeostasis and Tumor Progression Gastroenterology. 134: A-450. DOI: 10.1016/S0016-5085(08)62103-4 |
0.31 |
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| 2008 |
Tetreault M, Wang M, Goldstein BG, Yang Y, Yu Q, Klein-Szanto AJ, Rustgi AK, Katz JP. 177 Esophageal Squamous Cell Cancer in a Transgenic Mouse Model of KLF4 Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)60147-X |
0.391 |
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| 2007 |
Aggarwal P, Lessie MD, Lin DI, Pontano L, Gladden AB, Nuskey B, Goradia A, Wasik MA, Klein-Szanto AJ, Rustgi AK, Bassing CH, Diehl JA. Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication. Genes & Development. 21: 2908-22. PMID 18006686 DOI: 10.1101/Gad.1586007 |
0.355 |
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| 2007 |
Pasca di Magliano M, Biankin AV, Heiser PW, Cano DA, Gutierrez PJ, Deramaudt T, Segara D, Dawson AC, Kench JG, Henshall SM, Sutherland RL, Dlugosz A, Rustgi AK, Hebrok M. Common activation of canonical Wnt signaling in pancreatic adenocarcinoma. Plos One. 2: e1155. PMID 17982507 DOI: 10.1371/Journal.Pone.0001155 |
0.349 |
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| 2007 |
Okawa T, Michaylira CZ, Kalabis J, Stairs DB, Nakagawa H, Andl CD, Johnstone CN, Klein-Szanto AJ, El-Deiry WS, Cukierman E, Herlyn M, Rustgi AK. The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiation. Genes & Development. 21: 2788-803. PMID 17974918 DOI: 10.1101/Gad.1544507 |
0.459 |
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| 2007 |
Rustgi AK. The genetics of hereditary colon cancer Genes and Development. 21: 2525-2538. PMID 17938238 DOI: 10.1101/Gad.1593107 |
0.347 |
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| 2007 |
Plastaras JP, Kim SH, Liu YY, Dicker DT, Dorsey JF, McDonough J, Cerniglia G, Rajendran RR, Gupta A, Rustgi AK, Diehl JA, Smith CD, Flaherty KT, El-Deiry WS. Cell cycle dependent and schedule-dependent antitumor effects of sorafenib combined with radiation. Cancer Research. 67: 9443-54. PMID 17909054 DOI: 10.1158/0008-5472.Can-07-1473 |
0.334 |
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| 2007 |
Grandis JR, Carbone DP, Rustgi AK. Advances and challenges in aerodigestive epithelial cancer: Meeting summary and research opportunities Cancer Research. 67: 7556-7558. PMID 17686829 DOI: 10.1158/0008-5472.Can-07-1733 |
0.382 |
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| 2007 |
Guo M, House MG, Suzuki H, Ye Y, Brock MV, Lu F, Liu Z, Rustgi AK, Herman JG. Epigenetic silencing of CDX2 is a feature of squamous esophageal cancer International Journal of Cancer. 121: 1219-1226. PMID 17534889 DOI: 10.1002/Ijc.22828 |
0.405 |
|
| 2007 |
Lioni M, Brafford P, Andl C, Rustgi A, El-Deiry W, Herlyn M, Smalley KS. Dysregulation of claudin-7 leads to loss of E-cadherin expression and the increased invasion of esophageal squamous cell carcinoma cells. The American Journal of Pathology. 170: 709-21. PMID 17255337 DOI: 10.2353/Ajpath.2007.060343 |
0.379 |
|
| 2006 |
Rustgi AK. Models of Esophageal Carcinogenesis Seminars in Oncology. 33: 57-58. PMID 17178289 DOI: 10.1053/J.Seminoncol.2006.10.013 |
0.368 |
|
| 2006 |
Rustgi AK. The molecular pathogenesis of pancreatic cancer: Clarifying a complex circuitry Genes and Development. 20: 3049-3053. PMID 17114578 DOI: 10.1101/Gad.1501106 |
0.32 |
|
| 2006 |
Kim SH, Nakagawa H, Navaraj A, Naomoto Y, Klein-Szanto AJ, Rustgi AK, El-Deiry WS. Tumorigenic conversion of primary human esophageal epithelial cells using oncogene combinations in the absence of exogenous Ras. Cancer Research. 66: 10415-24. PMID 17079462 DOI: 10.1158/0008-5472.Can-06-2104 |
0.374 |
|
| 2006 |
Deramaudt TB, Sachdeva MM, Wescott MP, Chen Y, Stoffers DA, Rustgi AK. The PDX1 homeodomain transcription factor negatively regulates the pancreatic ductal cell-specific keratin 19 promoter. The Journal of Biological Chemistry. 281: 38385-95. PMID 17056599 DOI: 10.1074/Jbc.M605891200 |
0.368 |
|
| 2006 |
Andl CD, Fargnoli BB, Okawa T, Bowser M, Takaoka M, Nakagawa H, Klein-Szanto A, Hua X, Herlyn M, Rustgi AK. Coordinated functions of E-cadherin and transforming growth factor beta receptor II in vitro and in vivo. Cancer Research. 66: 9878-85. PMID 17047049 DOI: 10.1158/0008-5472.Can-05-4157 |
0.368 |
|
| 2006 |
Kobayashi M, Naomoto Y, Nobuhisa T, Okawa T, Takaoka M, Shirakawa Y, Yamatsuji T, Matsuoka J, Mizushima T, Matsuura H, Nakajima M, Nakagawa H, Rustgi A, Tanaka N. Heparanase regulates esophageal keratinocyte differentiation through nuclear translocation and heparan sulfate cleavage. Differentiation. 74: 235-243. PMID 16759289 DOI: 10.1111/J.1432-0436.2006.00072.X |
0.394 |
|
| 2006 |
Benzeno S, Lu F, Guo M, Barbash O, Zhang F, Herman JG, Klein PS, Rustgi A, Diehl JA. Identification of mutations that disrupt phosphorylation-dependent nuclear export of cyclin D1 Oncogene. 25: 6291-6303. PMID 16732330 DOI: 10.1038/Sj.Onc.1209644 |
0.33 |
|
| 2006 |
Deramaudt TB, Takaoka M, Upadhyay R, Bowser MJ, Porter J, Lee A, Rhoades B, Johnstone CN, Weissleder R, Hingorani SR, Mahmood U, Rustgi AK. N-cadherin and keratinocyte growth factor receptor mediate the functional interplay between Ki-RASG12V and p53V143A in promoting pancreatic cell migration, invasion, and tissue architecture disruption Molecular and Cellular Biology. 26: 4185-4200. PMID 16705170 DOI: 10.1128/Mcb.01055-05 |
0.405 |
|
| 2006 |
Hruban RH, Rustgi AK, Brentnall TA, Tempero MA, Wright CV, Tuveson DA. Pancreatic cancer in mice and man: the Penn Workshop 2004. Cancer Research. 66: 14-7. PMID 16397208 DOI: 10.1158/0008-5472.Can-05-3914 |
0.333 |
|
| 2006 |
El-Deiry WS, Rustgi AK. Cancer Biology: A new discipline with required reading Cancer Biology & Therapy. 5: 1415-1415. DOI: 10.4161/Cbt.5.10.3441 |
0.313 |
|
| 2005 |
Goessel G, Quante M, Hahn WC, Karada H, Heeg S, Suliman Y, Doebele M, Von Werder A, Fulda C, Nakagawa H, Rustgi AK, Blum HE, Opitz OG. Creating oral squamous cancer cells: A cellular model of oral-esophageal carcinogenesis Proceedings of the National Academy of Sciences of the United States of America. 102: 15599-15604. PMID 16239349 DOI: 10.1073/Pnas.0409730102 |
0.424 |
|
| 2005 |
Ouyang W, Ma Q, Li J, Zhang D, Liu ZG, Rustgi AK, Huang C. Cyclin D1 induction through IκB kinase β/nuclear factor-κB pathway is responsible for arsenite-induced increased cell cycle G 1-S phase transition in human keratinocytes Cancer Research. 65: 9287-9293. PMID 16230390 DOI: 10.1158/0008-5472.Can-05-0469 |
0.357 |
|
| 2005 |
Rustgi AK. Pancreatic cancer: Novel approaches to diagnosis and therapy Gastroenterology. 129: 1344-1347. PMID 16230087 DOI: 10.1053/J.Gastro.2005.08.036 |
0.302 |
|
| 2005 |
Deramaudt T, Rustgi AK. Mutant KRAS in the initiation of pancreatic cancer Biochimica Et Biophysica Acta - Reviews On Cancer. 1756: 97-101. PMID 16169155 DOI: 10.1016/J.Bbcan.2005.08.003 |
0.336 |
|
| 2005 |
Means AL, Meszoely IM, Suzuki K, Miyamoto Y, Rustgi AK, Coffey RJ, Wright CV, Stoffers DA, Leach SD. Pancreatic epithelial plasticity mediated by acinar cell transdifferentiation and generation of nestin-positive intermediates. Development (Cambridge, England). 132: 3767-76. PMID 16020518 DOI: 10.1242/Dev.01925 |
0.396 |
|
| 2005 |
Hingorani SR, Wang L, Multani AS, Combs C, Deramaudt TB, Hruban RH, Rustgi AK, Chang S, Tuveson DA. Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice. Cancer Cell. 7: 469-83. PMID 15894267 DOI: 10.1016/J.Ccr.2005.04.023 |
0.355 |
|
| 2005 |
Johnstone CN, Castellví-Bel S, Chang LM, Sung RK, Bowser MJ, Piqué JM, Castells A, Rustgi AK. PRR5 encodes a conserved proline-rich protein predominant in kidney: Analysis of genomic organization, expression, and mutation status in breast and colorectal carcinomas Genomics. 85: 338-351. PMID 15718101 DOI: 10.1016/J.Ygeno.2004.11.002 |
0.349 |
|
| 2005 |
Goessel G, Quante M, von Werder A, Heeg S, Doebele M, Doebele M, Fulda C, Nakagawa H, Suliman Y, Rustgi A, Hahn W, Blum H, Opitz O. Malignant transformation of primary human oral squamous epithelial cells using a defined set of genetic alterations Zeitschrift FüR Gastroenterologie. 43. DOI: 10.1055/S-2005-919794 |
0.324 |
|
| 2004 |
Mongroo PS, Johnstone CN, Naruszewicz I, Leung-Hagesteijn C, Sung RK, Carnio L, Rustgi AK, Hannigan GE. β-parvin inhibits integrin-linked kinase signaling and is downregulated in breast cancer Oncogene. 23: 8959-8970. PMID 15467740 DOI: 10.1038/Sj.Onc.1208112 |
0.348 |
|
| 2004 |
Halbert CH, Lynch H, Lynch J, Main D, Kucharski S, Rustgi AK, Lerman C. Colon cancer screening practices following genetic testing for hereditary nonpolyposis colon cancer (HNPCC) mutations Archives of Internal Medicine. 164: 1881-1887. PMID 15451763 DOI: 10.1001/Archinte.164.17.1881 |
0.315 |
|
| 2004 |
Andl CD, Mizushima T, Oyama K, Bowser M, Nakagawa H, Rustgi AK. EGFR-induced cell migration is mediated predominantly by the JAK-STAT pathway in primary esophageal keratinocytes American Journal of Physiology - Gastrointestinal and Liver Physiology. 287. PMID 15284024 DOI: 10.1152/Ajpgi.00253.2004 |
0.303 |
|
| 2004 |
Johnstone CN, Castellví-Bel S, Chang LM, Bessa X, Nakagawa H, Harada H, Sung RK, Piqué JM, Castells A, Rustgi AK. ARHGAP8 is a novel member of the RHOGAP family related to ARHGAP1/CDC42GAP/p50RHOGAP: mutation and expression analyses in colorectal and breast cancers. Gene. 336: 59-71. PMID 15225876 DOI: 10.1016/J.Gene.2004.01.025 |
0.333 |
|
| 2004 |
Kim K, Nakagawa H, Fei P, Rustgi AK, El-Deiry WS. Targeting Bcl-XL in esophageal squamous cancer to sensitize to chemotherapy plus TRAIL-induced apoptosis while normal epithelial cells are protected by blockade of caspase 9 Cell Death and Differentiation. 11: 583-587. PMID 14752513 DOI: 10.1038/Sj.Cdd.4401388 |
0.311 |
|
| 2003 |
Ohira T, Gemmill RM, Ferguson K, Kusy S, Roche J, Brambilla E, Zeng C, Baron A, Bemis L, Erickson P, Wilder E, Rustgi A, Kitajewski J, Gabrielson E, Bremnes R, et al. WNT7a induces E-cadherin in lung cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 10429-34. PMID 12937339 DOI: 10.1073/Pnas.1734137100 |
0.332 |
|
| 2003 |
Castellvı́-Bel S, Castells A, Johnstone CN, Piñol V, Pellisé M, Elizalde JI, Romo N, Rustgi AK, Piqué JM. Evaluation of PARVG located on 22q13 as a candidate tumor suppressor gene for colorectal and breast cancer. Cancer Genetics and Cytogenetics. 144: 80-82. PMID 12810262 DOI: 10.1016/S0165-4608(03)00034-7 |
0.364 |
|
| 2003 |
Okano Ji, Snyder L, Rustgi AK. Genetic alterations in esophageal cancer Methods in Molecular Biology (Clifton, N.J.). 222: 131-145. PMID 12710684 DOI: 10.1385/1-59259-328-3:131 |
0.319 |
|
| 2003 |
Chung DC, Rustgi AK. The Hereditary Nonpolyposis Colorectal Cancer Syndrome: Genetics and Clinical Implications Annals of Internal Medicine. 138: 560-570+I53. PMID 12667026 DOI: 10.7326/0003-4819-138-7-200304010-00012 |
0.336 |
|
| 2003 |
Andl CD, Mizushima T, Nakagawa H, Oyama K, Harada H, Chruma K, Herlyn M, Rustgi AK. Epidermal growth factor receptor mediates increased cell proliferation, migration, and aggregation in esophageal keratinocytes in vitro and in vivo Journal of Biological Chemistry. 278: 1824-1830. PMID 12435727 DOI: 10.1074/Jbc.M209148200 |
0.372 |
|
| 2003 |
Oyama K, Nakagawa H, Harada H, Andl CD, Takaoka M, Rustgi AK. Murine oral-epithelial cells have a subpopulation of potential stem cells Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)82310-7 |
0.331 |
|
| 2003 |
Quante M, Werder AV, Goessel G, Jacobmeier B, Suliman Y, Beijersbergen R, Rustgi AK, Blum HE, Opitz OG. Differential Transcription regulation of human telomerase in a cellular model of esophageal squamous carcinogenesis Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)81444-0 |
0.315 |
|
| 2003 |
Rustgi AK. Gene family analysis uncovers new therapeutic targets for colorectal cancers Gastroenterology. 125: 4. DOI: 10.1016/S0016-5085(03)00809-6 |
0.308 |
|
| 2002 |
Opitz OG, Harada H, Suliman Y, Rhoades B, Sharpless NE, Kent R, Kopelovich L, Nakagawa H, Rustgi AK. A mouse model of human oral-esophageal cancer. The Journal of Clinical Investigation. 110: 761-9. PMID 12235107 DOI: 10.1172/Jci15324 |
0.361 |
|
| 2001 |
Opitz OG, Suliman Y, Hahn WC, Harada H, Blum HE, Rustgi AK. Cyclin D1 overexpression and p53 inactivation immortalize primary oral keratinocytes by a telomerase-independent mechanism Journal of Clinical Investigation. 108: 725-732. PMID 11544278 DOI: 10.1016/S0016-5085(08)81445-X |
0.354 |
|
| 2001 |
Brembeck FH, Moffett J, Wang TC, Rustgi AK. The keratin 19 promoter is potent for cell-specific targeting of genes in transgenic mice. Gastroenterology. 120: 1720-8. PMID 11375953 DOI: 10.1053/Gast.2001.24846 |
0.333 |
|
| 2001 |
Okano JI, Rustgi AK. Paclitaxel Induces Prolonged Activation of the Ras/MEK/ERK Pathway Independently of Activating the Programmed Cell Death Machinery Journal of Biological Chemistry. 276: 19555-19564. PMID 11278851 DOI: 10.1016/S0016-5085(08)83290-8 |
0.308 |
|
| 2001 |
Nakagawa H, Mizushima T, Harada H, Suliman Y, Opitz OG, Rustgi AK. The β1 integrin-EGFR interaction may regulate cell fate decisions in esophageal epithelial keratinocyte stem cells Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)80304-6 |
0.318 |
|
| 2001 |
Mizushima T, Nakagawa H, Rustgi AK. Wnt 1 activates TCF/LEF transcription in esophageal squamous cell carcinoma Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)80224-7 |
0.333 |
|
| 2000 |
Okano JI, Gaslightwala I, Birnbaum MJ, Rustgi AK, Nakagawa H. Akt/protein kinase B isoforms are differentially regulated by epidermal growth factor stimulation Journal of Biological Chemistry. 275: 30934-30942. PMID 10908564 DOI: 10.1074/Jbc.M004112200 |
0.31 |
|
| 2000 |
Brembeck FH, Rustgi AK. The tissue-dependent keratin 19 gene transcription is regulated by GKLF/KLF4 and Sp1 Journal of Biological Chemistry. 275: 28230-28239. PMID 10859317 DOI: 10.1074/Jbc.M004013200 |
0.396 |
|
| 2000 |
Brembeck FH, Opitz OG, Libermann TA, Rustgi AK. Dual function of the epithelial specific ets transcription factor, ELF3, in modulating differentiation Oncogene. 19: 1941-1949. PMID 10773884 DOI: 10.1038/Sj.Onc.1203441 |
0.355 |
|
| 2000 |
Opitz OG, Togawa K, Rustgi AK. Ectopic expression of cyclin D1 and dominant-negative p53 leads to immortalization of primary oral epithelial cells Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)85568-7 |
0.334 |
|
| 2000 |
Opitz OG, Suliman Y, Rhoades B, Sharpless NE, Rustgi AK. The combination of cyclin D1 overexpression and p53 inactivation is critical for oral-esophageal carcinogenesis in transgenic mice Gastroenterology. 118: A768. DOI: 10.1016/S0016-5085(00)85209-9 |
0.33 |
|
| 2000 |
Okano J, Gaslightwala I, Nakagawa H, Birnbaum MJ, Rustgi AK. Epidermal growth factor induced phosphoinositide 3-OH kinase pathway dependent activation of protein kinase B/Akt in human esophageal cancer cell lines Gastroenterology. 118: A90. DOI: 10.1016/S0016-5085(00)82438-5 |
0.324 |
|
| 2000 |
Nakagawa H, Okano J, Gaslightwala I, Landis AJ, Rustgi AK. The T cell factor (TCF)-B-catenin complex is present in nuclei but paradoxically transcriptionally inactive in esophageal cancer Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)82267-2 |
0.324 |
|
| 2000 |
Okano JI, Opitz OG, Nakagawa H, Jenkins TD, Friedman SL, Rustgi AK. The Kruppel-like transcriptional factors Zf9 and GKLF coactivate the human keratin 4 promoter and physically interact Febs Letters. 473: 95-100. DOI: 10.1016/S0014-5793(00)01468-X |
0.391 |
|
| 1999 |
Castells A, Ino Y, Louis DN, Ramesh V, Gusella JF, Rustgi AK. Mapping of a target region of allelic loss to a 0.5-cM interval on chromosome 22q13 in human colorectal cancer. Gastroenterology. 117: 831-7. PMID 10500065 DOI: 10.1016/S0016-5085(99)70341-0 |
0.315 |
|
| 1998 |
Compton CC, Warland G, Nakagawa H, Opitz OG, Rustgi AK. Cellular characterization and successful transfection of serially subcultured normal human esophageal keratinocytes Journal of Cellular Physiology. 177: 274-281. PMID 9766524 DOI: 10.1016/S0016-5085(98)82692-9 |
0.347 |
|
| 1998 |
Opitz OG, Jenkins TD, Rustgi AK. Transcriptional regulation of the differentiation-linked human K4 promoter is dependent upon esophageal-specific nuclear factors Journal of Biological Chemistry. 273: 23912-23921. PMID 9727005 DOI: 10.1074/Jbc.273.37.23912 |
0.347 |
|
| 1998 |
Ness SL, Edelmann W, Jenkins TD, Liedtke W, Rustgi AK, Kucherlapati R. Mouse keratin 4 is necessary for internal epithelial integrity. The Journal of Biological Chemistry. 273: 23904-11. PMID 9727004 DOI: 10.1074/Jbc.273.37.23904 |
0.304 |
|
| 1998 |
Rustgi AK. Cyclooxygenase-2: The future is now Nature Medicine. 4: 773-774. PMID 9662366 DOI: 10.1038/Nm0798-773 |
0.313 |
|
| 1998 |
Jenkins TD, Opitz OG, Okano JI, Rustgi AK. Transactivation of the human keratin 4 and Epstein-Barr virus ED-L2 promoters by gut-enriched Kruppel-like factor Journal of Biological Chemistry. 273: 10747-10754. PMID 9553140 DOI: 10.1074/Jbc.273.17.10747 |
0.342 |
|
| 1997 |
Rivera JA, Graeme-Cook F, Werner J, Z'graggen K, Rustgi AK, Rattner DW, Warshaw AL, Castillo CF. A rat model of pancreatic ductal adenocarcinoma: targeting chemical carcinogens. Surgery. 122: 82-90. PMID 9225919 DOI: 10.1016/S0039-6060(97)90268-3 |
0.347 |
|
| 1997 |
Nakagawa H, Inomoto T, Rustgi AK. A CACCC box-like cis-regulatory element of the Epstein-Barr virus ED-L2 promoter interacts with a novel transcriptional factor in tissue-specific squamous epithelia Journal of Biological Chemistry. 272: 16688-16699. PMID 9195985 DOI: 10.1074/Jbc.272.26.16688 |
0.35 |
|
| 1997 |
Nakagawa H, Wang TC, Zukerberg L, Odze R, Togawa K, May GH, Wilson J, Rustgi AK. The targeting of the cyclin D1 oncogene by an Epstein-Barr virus promoter in transgenic mice causes dysplasia in the tongue, esophagus and forestomach. Oncogene. 14: 1185-90. PMID 9121767 DOI: 10.1038/Sj.Onc.1200937 |
0.368 |
|
| 1997 |
Muller A, Nakagawa H, Rustgi AK. Retinoic acid and N-(4-hydroxy-phenyl) retinamide suppress growth of esophageal squamous carcinoma cell lines Cancer Letters. 113: 95-101. PMID 9065807 DOI: 10.1016/S0304-3835(97)04601-6 |
0.306 |
|
| 1997 |
Rivera JA, Rall CJN, Graeme-Cook F, Castillo CF, Shu P, Lakey N, Tepper R, Rattner DW, Warshaw AL, Rustgi AK. Analysis of K-ras oncogene mutations in chronic pancreatitis with ductal hyperplasia Surgery. 121: 42-49. PMID 9001550 DOI: 10.1016/S0039-6060(97)90181-1 |
0.305 |
|
| 1997 |
Rustgi AK. Prevention and Early Detection of Colorectal Cancer Annals of Surgery. 225: 439. DOI: 10.1097/00000658-199704000-00014 |
0.308 |
|
| 1996 |
Rall CJ, Yan YX, Graeme-Cook F, Beauchamp R, Yandell DW, Povoski SP, Rustgi AK. Ki-ras and p53 mutations in pancreatic ductal adenocarcinoma. Pancreas. 12: 10-7. PMID 8927612 DOI: 10.1097/00006676-199601000-00002 |
0.352 |
|
| 1996 |
Rustgi AK. MAD about colorectal cancer Gastroenterology. 111: 1387-1398. PMID 8898656 DOI: 10.1053/Gast.1996.V111.Agast961111387 |
0.323 |
|
| 1996 |
Jones RM, Branda J, Johnston KA, Polymenis M, Gadd M, Rustgi A, Callanan L, Schmidt EV. An essential E box in the promoter of the gene encoding the mRNA cap-binding protein (eukaryotic initiation factor 4E) is a target for activation by c-myc. Molecular and Cellular Biology. 16: 4754-64. PMID 8756633 DOI: 10.1128/Mcb.16.9.4754 |
0.308 |
|
| 1995 |
Liu Q, Yan YX, McClure M, Nakagawa H, Fujimura F, Rustgi AK. MTS-1 (CDKN2) tumor suppressor gene deletions are a frequent event in esophagus squamous cancer and pancreatic adenocarcinoma cell lines Oncogene. 10: 619-622. PMID 7845688 |
0.305 |
|
| 1995 |
Chung DC, Rustgi AK. DNA mismatch repair and cancer Gastroenterology. 109: 1685-1699. PMID 7557155 DOI: 10.1016/0016-5085(95)90660-6 |
0.322 |
|
| 1995 |
Rustgi AK, Xu L, Pinney D, Sterner C, Beauchamp R, Schmidt S, Gusella JF, Ramesh V. Neurofibromatosis 2 gene in human colorectal cancer. Cancer Genetics and Cytogenetics. 84: 24-6. PMID 7497438 DOI: 10.1016/0165-4608(95)00059-3 |
0.354 |
|
| 1995 |
Rall CJN, Rustgi AK. Novel CD44v6 isoform overexpressed in metastases of pancreatic adenocarcinoma Gastroenterology. 108. DOI: 10.1016/0016-5085(95)24199-X |
0.307 |
|
| 1994 |
Rustgi AK. Hereditary gastrointestinal polyposis and nonpolyposis syndromes New England Journal of Medicine. 331: 1694-1702. PMID 7969362 DOI: 10.1056/Nejm199412223312507 |
0.325 |
|
| 1994 |
Schroy PC, Rustgi AK, Ikonomu E, Liu XP, Polito J, Andry C, O'Keane JC. Growth and intestinal differentiation are independently regulated in HT29 colon cancer cells Journal of Cellular Physiology. 161: 111-123. PMID 7929596 DOI: 10.1002/Jcp.1041610114 |
0.343 |
|
| 1994 |
Togawa K, Jaskiewicz K, Takahashi H, Meltzer SJ, Rustgi AK. Human papillomavirus DNA sequences in esophagus squamous cell carcinoma. Gastroenterology. 107: 128-36. PMID 7912679 DOI: 10.1016/0016-5085(94)90070-1 |
0.334 |
|
| 1993 |
Rustgi AK. Ornithine decarboxylase: An oncogene? Gastroenterology. 105: 1255-1256. PMID 8405875 DOI: 10.1016/0016-5085(93)90980-Q |
0.309 |
|
| 1993 |
Rustgi AK. Molecular genetics and colorectal cancer Gastroenterology. 104: 1223-1225. PMID 8385044 DOI: 10.1016/0016-5085(93)90302-S |
0.313 |
|
| 1993 |
Rustgi AK. The genetics of colon cancer Seminars in Radiation Oncology. 3: 2-7. DOI: 10.1016/S1053-4296(05)80071-2 |
0.321 |
|
| 1992 |
Rustgi AK, Podolsky DK. The molecular basis of colon cancer Annual Review of Medicine. 43: 61-68. PMID 1580606 DOI: 10.1146/Annurev.Me.43.020192.000425 |
0.365 |
|
| 1991 |
Rustgi AK, Dyson N, Hill D, Bernards R. The c-myc oncoprotein forms a specific complex with the product of the retinoblastoma gene Cold Spring Harbor Symposia On Quantitative Biology. 56: 163-167. PMID 1840250 DOI: 10.1101/Sqb.1991.056.01.021 |
0.312 |
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