Year |
Citation |
Score |
2023 |
Fettweis G, Johnson TA, Almeida-Prieto B, Weller-Pérez J, Presman DM, Hager GL, Alvarez de la Rosa D. The mineralocorticoid receptor forms higher order oligomers upon DNA binding. Protein Science : a Publication of the Protein Society. e4890. PMID 38160317 DOI: 10.1002/pro.4890 |
0.319 |
|
2023 |
Wagh K, Stavreva DA, Upadhyaya A, Hager GL. Transcription Factor Dynamics: One Molecule at a Time. Annual Review of Cell and Developmental Biology. PMID 37540844 DOI: 10.1146/annurev-cellbio-022823-013847 |
0.337 |
|
2023 |
Tettey TT, Rinaldi L, Hager GL. Long-range gene regulation in hormone-dependent cancer. Nature Reviews. Cancer. PMID 37537310 DOI: 10.1038/s41568-023-00603-4 |
0.366 |
|
2023 |
Wagh K, Stavreva DA, Jensen RAM, Paakinaho V, Fettweis G, Schiltz RL, Wüstner D, Mandrup S, Presman DM, Upadhyaya A, Hager GL. Dynamic switching of transcriptional regulators between two distinct low-mobility chromatin states. Science Advances. 9: eade1122. PMID 37315128 DOI: 10.1126/sciadv.ade1122 |
0.336 |
|
2023 |
Johnson TA, Fettweis G, Wagh K, Almeida-Prieto B, Hager GL, de la Rosa DA. The Glucocorticoid Receptor is Required for Efficient Aldosterone-Induced Transcription by the Mineralocorticoid Receptor. Biorxiv : the Preprint Server For Biology. PMID 36789429 DOI: 10.1101/2023.01.26.525745 |
0.38 |
|
2023 |
Fettweis G, Johnson TA, Almeida-Prieto B, Presman DM, Hager GL, de la Rosa DA. The mineralocorticoid receptor forms higher order oligomers upon DNA binding. Biorxiv : the Preprint Server For Biology. PMID 36789424 DOI: 10.1101/2023.01.26.525752 |
0.339 |
|
2022 |
Jiménez-Panizo A, Alegre-Martí A, Tettey TT, Fettweis G, Abella M, Antón R, Johnson TA, Kim S, Schiltz RL, Núñez-Barrios I, Font-Díaz J, Caelles C, Valledor AF, Pérez P, Rojas AM, ... ... Hager GL, et al. The multivalency of the glucocorticoid receptor ligand-binding domain explains its manifold physiological activities. Nucleic Acids Research. PMID 36464162 DOI: 10.1093/nar/gkac1119 |
0.324 |
|
2022 |
Zhao Y, Vartak SV, Conte A, Wang X, Garcia DA, Stevens E, Kyoung Jung S, Kieffer-Kwon KR, Vian L, Stodola T, Moris F, Chopp L, Preite S, Schwartzberg PL, Kulinski JM, ... ... Hager G, et al. "Stripe" transcription factors provide accessibility to co-binding partners in mammalian genomes. Molecular Cell. PMID 35863348 DOI: 10.1016/j.molcel.2022.06.029 |
0.352 |
|
2022 |
Rinaldi L, Fettweis G, Kim S, Garcia DA, Fujiwara S, Johnson TA, Tettey TT, Ozbun L, Pegoraro G, Puglia M, Blagoev B, Upadhyaya A, Stavreva DA, Hager GL. The glucocorticoid receptor associates with the cohesin loader NIPBL to promote long-range gene regulation. Science Advances. 8: eabj8360. PMID 35353576 DOI: 10.1126/sciadv.abj8360 |
0.375 |
|
2021 |
Amin R, Shukla A, Zhu JJ, Kim S, Wang P, Tian SZ, Tran AD, Paul D, Cappell SD, Burkett S, Liu H, Lee MP, Kruhlak MJ, Dwyer JE, Simpson RM, ... Hager GL, et al. Nuclear pore protein NUP210 depletion suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response. Nature Communications. 12: 7216. PMID 34903738 DOI: 10.1038/s41467-021-27451-w |
0.305 |
|
2021 |
Flynn BP, Birnie MT, Kershaw YM, Pauza AG, Kim S, Baek S, Rogers MF, Paterson AR, Stavreva DA, Murphy D, Hager GL, Lightman SL, Conway-Campbell BL. Corticosterone pattern-dependent glucocorticoid receptor binding and transcriptional regulation within the liver. Plos Genetics. 17: e1009737. PMID 34375333 DOI: 10.1371/journal.pgen.1009737 |
0.304 |
|
2021 |
Johnson TA, Paakinaho V, Kim S, Hager GL, Presman DM. Genome-wide binding potential and regulatory activity of the glucocorticoid receptor's monomeric and dimeric forms. Nature Communications. 12: 1987. PMID 33790284 DOI: 10.1038/s41467-021-22234-9 |
0.344 |
|
2021 |
Garcia DA, Johnson TA, Presman DM, Fettweis G, Wagh K, Rinaldi L, Stavreva DA, Paakinaho V, Jensen RAM, Mandrup S, Upadhyaya A, Hager GL. An intrinsically disordered region-mediated confinement state contributes to the dynamics and function of transcription factors. Molecular Cell. PMID 33561389 DOI: 10.1016/j.molcel.2021.01.013 |
0.35 |
|
2020 |
Rosa DAdl, Johnson TA, Fettweis G, Hager GL. OR12-03 Mineralocorticoid and Glucocorticoid Receptors Adopt Distinct Quaternary Structures and Can Form Heteromultimers That Affect Chromatin-Binding Profiles Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.1651 |
0.413 |
|
2020 |
Goelzer J, Figueroa A, Stavreva DA, Hager G, Ferguson ML. Ligand Dependence of Hormone Action in Glucocorticoid Receptor Studied by 3D Orbital Tracking Fluorescence Cross Correlation Spectroscopy Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.1753 |
0.312 |
|
2019 |
Paul-Friedman K, Martin M, Crofton KM, Hsu CW, Sakamuru S, Zhao J, Xia M, Huang R, Stavreva DA, Soni V, Varticovski L, Raziuddin R, Hager GL, Houck KA. Limited Chemical Structural Diversity Found to Modulate Thyroid Hormone Receptor in the Tox21 Chemical Library. Environmental Health Perspectives. 127: 97009. PMID 31566444 DOI: 10.1289/Ehp5314 |
0.335 |
|
2019 |
Paakinaho V, Swinstead EE, Presman DM, Grøntved L, Hager GL. Meta-analysis of Chromatin Programming by Steroid Receptors. Cell Reports. 28: 3523-3534.e2. PMID 31553919 DOI: 10.1016/J.Celrep.2019.08.039 |
0.495 |
|
2019 |
Stavreva DA, Garcia DA, Fettweis G, Gudla PR, Zaki GF, Soni V, McGowan A, Williams G, Huynh A, Palangat M, Schiltz RL, Johnson TA, Presman DM, Ferguson ML, Pegoraro G, ... ... Hager GL, et al. Transcriptional Bursting and Co-bursting Regulation by Steroid Hormone Release Pattern and Transcription Factor Mobility. Molecular Cell. PMID 31421980 DOI: 10.1016/J.Molcel.2019.06.042 |
0.395 |
|
2019 |
Paakinaho V, Johnson TA, Presman DM, Hager GL. Glucocorticoid receptor quaternary structure drives chromatin occupancy and transcriptional outcome. Genome Research. PMID 31337711 DOI: 10.1101/Gr.244814.118 |
0.497 |
|
2019 |
Taves MD, Mittelstadt PR, Presman DM, Hager GL, Ashwell JD. Single-Cell Resolution and Quantitation of Targeted Glucocorticoid Delivery in the Thymus. Cell Reports. 26: 3629-3642.e4. PMID 30917317 DOI: 10.1016/J.Celrep.2019.02.108 |
0.398 |
|
2019 |
Fujiwara S, Baek S, Varticovski L, Kim S, Hager GL. High Quality ATAC-Seq Data Recovered from Cryopreserved Breast Cell Lines and Tissue. Scientific Reports. 9: 516. PMID 30679562 DOI: 10.1038/S41598-018-36927-7 |
0.373 |
|
2019 |
Paakinaho V, Johnson T, Presman D, Hager G. OR26-6 Glucocorticoid Receptor Quaternary Structure Drives Chromatin Occupancy and Transcriptional Outcome Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Or26-6 |
0.409 |
|
2019 |
Goelzer JA, Stavreva DA, Hager GL, Ferguson ML. Transcriptional Activation by Glucocorticoid Receptor Studied by 3D Orbital Tracking Fluorescence Cross Correlation Spectroscopy Biophysical Journal. 116: 298a-299a. DOI: 10.1016/J.Bpj.2018.11.1618 |
0.364 |
|
2018 |
Oh KS, Gottschalk RA, Lounsbury NW, Sun J, Dorrington MG, Baek S, Sun G, Wang Z, Krauss KS, Milner JD, Dutta B, Hager GL, Sung MH, Fraser IDC. Dual Roles for Ikaros in Regulation of Macrophage Chromatin State and Inflammatory Gene Expression. Journal of Immunology (Baltimore, Md. : 1950). PMID 29898962 DOI: 10.4049/Jimmunol.1800158 |
0.423 |
|
2018 |
Swinstead EE, Paakinaho V, Hager GL. Chromatin reprogramming in breast cancer. Endocrine-Related Cancer. 25: R385-R404. PMID 29692347 DOI: 10.1530/Erc-18-0033 |
0.389 |
|
2017 |
Goldstein I, Paakinaho V, Baek S, Sung MH, Hager GL. Synergistic gene expression during the acute phase response is characterized by transcription factor assisted loading. Nature Communications. 8: 1849. PMID 29185442 DOI: 10.1038/S41467-017-02055-5 |
0.375 |
|
2017 |
Johnson TA, Chereji RV, Stavreva DA, Morris SA, Hager GL, Clark DJ. Conventional and pioneer modes of glucocorticoid receptor interaction with enhancer chromatin in vivo. Nucleic Acids Research. PMID 29126175 DOI: 10.1093/Nar/Gkx1044 |
0.484 |
|
2017 |
Goldstein I, Hager GL. The three D's of transcription activation by glucagon - direct, delayed and dynamic. Endocrinology. PMID 29077799 DOI: 10.1210/En.2017-00521 |
0.443 |
|
2017 |
Kieffer-Kwon KR, Nimura K, Rao SSP, Xu J, Jung S, Pekowska A, Dose M, Stevens E, Mathe E, Dong P, Huang SC, Ricci MA, Baranello L, Zheng Y, Ardori FT, ... ... Hager G, et al. Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation. Molecular Cell. PMID 28803781 DOI: 10.1016/J.Molcel.2017.07.013 |
0.479 |
|
2017 |
Oh KS, Patel H, Gottschalk RA, Lee WS, Baek S, Fraser IDC, Hager GL, Sung MH. Anti-Inflammatory Chromatinscape Suggests Alternative Mechanisms of Glucocorticoid Receptor Action. Immunity. PMID 28801231 DOI: 10.1016/J.Immuni.2017.07.012 |
0.382 |
|
2017 |
Paakinaho V, Presman DM, Ball DA, Johnson TA, Schiltz RL, Levitt P, Mazza D, Morisaki T, Karpova TS, Hager GL. Single-molecule analysis of steroid receptor and cofactor action in living cells. Nature Communications. 8: 15896. PMID 28635963 DOI: 10.1038/Ncomms15896 |
0.446 |
|
2017 |
Goldstein I, Hager GL. Dynamic enhancer function in the chromatin context. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. PMID 28544514 DOI: 10.1002/Wsbm.1390 |
0.42 |
|
2017 |
Baek S, Goldstein I, Hager GL. Bivariate Genomic Footprinting Detects Changes in Transcription Factor Activity. Cell Reports. 19: 1710-1722. PMID 28538187 DOI: 10.1016/J.Celrep.2017.05.003 |
0.447 |
|
2017 |
Lynch C, Sakamuru S, Huang R, Stavreva DA, Varticovski L, Hager GL, Judson RS, Houck KA, Kleinstreuer NC, Casey W, Paules RS, Simeonov A, Xia M. Identifying Environmental Chemicals as Agonists of the Androgen Receptor by Using a Quantitative High-throughput Screening Platform. Toxicology. PMID 28478275 DOI: 10.1016/J.Tox.2017.05.001 |
0.362 |
|
2017 |
Presman DM, Ball DA, Paakinaho V, Grimm JB, Lavis LD, Karpova TS, Hager GL. Quantifying transcription factor binding dynamics at the single-molecule level in live cells. Methods (San Diego, Calif.). PMID 28315485 DOI: 10.1016/J.Ymeth.2017.03.014 |
0.368 |
|
2017 |
Pooley JR, Flynn BP, Grøntved L, Baek S, Guertin MJ, Kershaw YM, Birnie MT, Pellatt A, Rivers CA, Schiltz RL, Hager GL, Lightman SL, Conway-Campbell BL. Genome-wide identification of basic helix-loop helix and NF-1 motifs underlying GR binding sites in male rat hippocampus. Endocrinology. PMID 28200020 DOI: 10.1210/En.2016-1929 |
0.435 |
|
2017 |
Veschi V, Liu Z, Voss TC, Ozbun L, Gryder B, Yan C, Hu Y, Ma A, Jin J, Mazur SJ, Lam N, Souza BK, Giannini G, Hager GL, Arrowsmith CH, et al. Epigenetic siRNA and Chemical Screens Identify SETD8 Inhibition as a Therapeutic Strategy for p53 Activation in High-Risk Neuroblastoma. Cancer Cell. 31: 50-63. PMID 28073004 DOI: 10.1016/J.Ccell.2016.12.002 |
0.323 |
|
2017 |
Siersbæk M, Varticovski L, Yang S, Baek S, Nielsen R, Mandrup S, Hager GL, Chung JH, Grøntved L. High fat diet-induced changes of mouse hepatic transcription and enhancer activity can be reversed by subsequent weight loss. Scientific Reports. 7: 40220. PMID 28071704 DOI: 10.1038/Srep40220 |
0.33 |
|
2017 |
Goldstein I, Baek S, Sung M, Hager GL. Abstract 5510: Pro inflammatory cytokines induce synergistic gene expression by assisted loading of STAT3 at a subset of primed enhancers Cancer Research. 77: 5510-5510. DOI: 10.1158/1538-7445.Am2017-5510 |
0.324 |
|
2017 |
Swinstead E, Miranda T, Paakinaho V, Beak S, Hager G. Abstract 5499: The reprogramming of the steroid receptor binding landscape at active enhancers is associated with a fast DNA residence time through a mechanism termed dynamic assisted loading in breast cancer cells Cancer Research. 77: 5499-5499. DOI: 10.1158/1538-7445.Am2017-5499 |
0.37 |
|
2016 |
Goldstein I, Baek S, Presman DM, Pakkinaho V, Swinstead EE, Hager GL. Transcription factor assisted loading and enhancer dynamics dictate the hepatic fasting response. Genome Research. PMID 28031249 DOI: 10.1101/Gr.212175.116 |
0.467 |
|
2016 |
Sawyer IA, Sturgill D, Sung MH, Hager GL, Dundr M. Cajal body function in genome organization and transcriptome diversity. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. PMID 27767214 DOI: 10.1002/Bies.201600144 |
0.381 |
|
2016 |
Presman DM, Hager GL. More than meets the dimer: What is the quaternary structure of the glucocorticoid receptor? Transcription. 0. PMID 27764575 DOI: 10.1080/21541264.2016.1249045 |
0.339 |
|
2016 |
Sawyer IA, Hager GL, Dundr M. Specific genomic cues regulate Cajal body assembly. Rna Biology. 0. PMID 27715441 DOI: 10.1080/15476286.2016.1243648 |
0.39 |
|
2016 |
Swinstead EE, Paakinaho V, Presman DM, Hager GL. Pioneer factors and ATP-dependent chromatin remodeling factors interact dynamically: A new perspective: Multiple transcription factors can effect chromatin pioneer functions through dynamic interactions with ATP-dependent chromatin remodeling factors. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. PMID 27633730 DOI: 10.1002/Bies.201600137 |
0.472 |
|
2016 |
Stavreva DA, Varticovski L, Levkova L, George AA, Davis L, Pegoraro G, Blazer V, Iwanowicz L, Hager GL. Novel cell-based assay for detection of thyroid receptor beta-interacting environmental contaminants. Toxicology. PMID 27528272 DOI: 10.1016/J.Tox.2016.08.012 |
0.337 |
|
2016 |
Presman DM, Ganguly S, Schiltz RL, Johnson TA, Karpova TS, Hager GL. DNA binding triggers tetramerization of the glucocorticoid receptor in live cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 27382178 DOI: 10.1073/pnas.1606774113 |
0.405 |
|
2016 |
Swinstead EE, Miranda TB, Paakinaho V, Baek S, Goldstein I, Hawkins M, Karpova TS, Ball D, Mazza D, Lavis LD, Grimm JB, Morisaki T, Grøntved L, Presman DM, Hager GL. Steroid Receptors Reprogram FoxA1 Occupancy through Dynamic Chromatin Transitions. Cell. PMID 27062924 DOI: 10.1016/J.Cell.2016.02.067 |
0.454 |
|
2016 |
Tesikova M, Dezitter X, Nenseth HZ, Klokk TI, Mueller F, Hager GL, Saatcioglu F. Divergent Binding and Transactivation by Two Related Steroid Receptors at the Same Response Element. The Journal of Biological Chemistry. PMID 27056330 DOI: 10.1074/Jbc.M115.684480 |
0.496 |
|
2016 |
Wang Q, Sawyer IA, Sung MH, Sturgill D, Shevtsov SP, Pegoraro G, Hakim O, Baek S, Hager GL, Dundr M. Cajal bodies are linked to genome conformation. Nature Communications. 7: 10966. PMID 26997247 DOI: 10.1038/Ncomms10966 |
0.353 |
|
2016 |
Sung MH, Baek S, Hager GL. Genome-wide footprinting: ready for prime time? Nature Methods. 13: 222-8. PMID 26914206 DOI: 10.1038/Nmeth.3766 |
0.354 |
|
2016 |
Thompson B, Varticovski L, Baek S, Hager GL. Genome-Wide Chromatin Landscape Transitions Identify Novel Pathways in Early Commitment to Osteoblast Differentiation. Plos One. 11: e0148619. PMID 26890492 DOI: 10.1371/Journal.Pone.0148619 |
0.383 |
|
2016 |
Stavreva DA, Hager GL. Chromatin structure and gene regulation: a dynamic view of enhancer function. Nucleus (Austin, Tex.). 1-7. PMID 26765055 DOI: 10.1080/19491034.2015.1107689 |
0.494 |
|
2015 |
Goldstein I, Hager GL. Transcriptional and Chromatin Regulation during Fasting - The Genomic Era. Trends in Endocrinology and Metabolism: Tem. PMID 26520657 DOI: 10.1016/J.Tem.2015.09.005 |
0.441 |
|
2015 |
Muratcioglu S, Presman DM, Pooley JR, Grøntved L, Hager GL, Nussinov R, Keskin O, Gursoy A. Structural Modeling of GR Interactions with the SWI/SNF Chromatin Remodeling Complex and C/EBP. Biophysical Journal. 109: 1227-39. PMID 26278180 DOI: 10.1016/J.Bpj.2015.06.044 |
0.459 |
|
2015 |
Grøntved L, Waterfall JJ, Kim DW, Baek S, Sung MH, Zhao L, Park JW, Nielsen R, Walker RL, Zhu YJ, Meltzer PS, Hager GL, Cheng SY. Transcriptional activation by the thyroid hormone receptor through ligand-dependent receptor recruitment and chromatin remodelling. Nature Communications. 6: 7048. PMID 25916672 DOI: 10.1038/Ncomms8048 |
0.509 |
|
2015 |
Salomon-Kent R, Marom R, John S, Dundr M, Schiltz LR, Gutierrez J, Workman J, Benayahu D, Hager GL. New Face for Chromatin-Related Mesenchymal Modulator: n-CHD9 Localizes to Nucleoli and Interacts With Ribosomal Genes. Journal of Cellular Physiology. 230: 2270-80. PMID 25689118 DOI: 10.1002/Jcp.24960 |
0.456 |
|
2015 |
Stavreva DA, Coulon A, Baek S, Sung MH, John S, Stixova L, Tesikova M, Hakim O, Miranda T, Hawkins M, Stamatoyannopoulos JA, Chow CC, Hager GL. Dynamics of chromatin accessibility and long-range interactions in response to glucocorticoid pulsing. Genome Research. 25: 845-57. PMID 25677181 DOI: 10.1101/Gr.184168.114 |
0.422 |
|
2015 |
Varticovski L, Kim S, Nickerson ML, Thompson B, Lao Q, Grøntved L, Baek S, Sung M, Theodorescu D, Dean M, Hager GL. Abstract 4783: Novel molecular markers of bladder cancer progression identified by global chromatin profiling Cancer Research. 75: 4783-4783. DOI: 10.1158/1538-7445.Am2015-4783 |
0.352 |
|
2014 |
Sung MH, Guertin MJ, Baek S, Hager GL. DNase footprint signatures are dictated by factor dynamics and DNA sequence. Molecular Cell. 56: 275-85. PMID 25242143 DOI: 10.1016/J.Molcel.2014.08.016 |
0.413 |
|
2014 |
Guertin MJ, Zhang X, Anguish L, Kim S, Varticovski L, Lis JT, Hager GL, Coonrod SA. Targeted H3R26 deimination specifically facilitates estrogen receptor binding by modifying nucleosome structure. Plos Genetics. 10: e1004613. PMID 25211228 DOI: 10.1371/Journal.Pgen.1004613 |
0.494 |
|
2014 |
Nenseth HZ, Dezitter X, Tesikova M, Mueller F, Klokk TI, Hager GL, Saatcioglu F. Distinctly different dynamics and kinetics of two steroid receptors at the same response elements in living cells. Plos One. 9: e105204. PMID 25133404 DOI: 10.1371/Journal.Pone.0105204 |
0.469 |
|
2014 |
Guertin MJ, Zhang X, Coonrod SA, Hager GL. Transient estrogen receptor binding and p300 redistribution support a squelching mechanism for estradiol-repressed genes. Molecular Endocrinology (Baltimore, Md.). 28: 1522-33. PMID 25051172 DOI: 10.1210/Me.2014-1130 |
0.44 |
|
2014 |
Siersbæk R, Baek S, Rabiee A, Nielsen R, Traynor S, Clark N, Sandelin A, Jensen ON, Sung MH, Hager GL, Mandrup S. Molecular architecture of transcription factor hotspots in early adipogenesis. Cell Reports. 7: 1434-42. PMID 24857666 DOI: 10.1016/J.Celrep.2014.04.043 |
0.439 |
|
2014 |
Presman DM, Ogara MF, Stortz M, Alvarez LD, Pooley JR, Schiltz RL, Grøntved L, Johnson TA, Mittelstadt PR, Ashwell JD, Ganesan S, Burton G, Levi V, Hager GL, Pecci A. Live cell imaging unveils multiple domain requirements for in vivo dimerization of the glucocorticoid receptor. Plos Biology. 12: e1001813. PMID 24642507 DOI: 10.1371/Journal.Pbio.1001813 |
0.423 |
|
2014 |
Sung MH, Li N, Lao Q, Gottschalk RA, Hager GL, Fraser ID. Switching of the relative dominance between feedback mechanisms in lipopolysaccharide-induced NF-κB signaling. Science Signaling. 7: ra6. PMID 24425788 DOI: 10.1126/Scisignal.2004764 |
0.345 |
|
2014 |
Voss TC, Hager GL. Dynamic regulation of transcriptional states by chromatin and transcription factors. Nature Reviews. Genetics. 15: 69-81. PMID 24342920 DOI: 10.1038/Nrg3623 |
0.443 |
|
2014 |
Morris SA, Baek S, Sung MH, John S, Wiench M, Johnson TA, Schiltz RL, Hager GL. Overlapping chromatin-remodeling systems collaborate genome wide at dynamic chromatin transitions. Nature Structural & Molecular Biology. 21: 73-81. PMID 24317492 DOI: 10.1038/Nsmb.2718 |
0.401 |
|
2014 |
Dull AB, George AA, Goncharova EI, Evans JR, Wamiru A, Cartner LK, Hager GL, McMahon JB. Identification of compounds by high-content screening that induce cytoplasmic to nuclear localization of a fluorescent estrogen receptor α chimera and exhibit agonist or antagonist activity in vitro. Journal of Biomolecular Screening. 19: 242-52. PMID 24051224 DOI: 10.1177/1087057113504136 |
0.36 |
|
2014 |
Kim S, Varticovski L, Grontved L, Baek S, Thompson B, Dean M, Theodoresco D, Nickerson ML, Hager GL. Abstract 474: Changes in global chromatin landscape identify bladder cancer progression Cancer Research. 74: 474-474. DOI: 10.1158/1538-7445.Am2014-474 |
0.358 |
|
2014 |
Morris SA, Baek S, Sung M, John S, Wiench M, Johnson TA, Schiltz RL, Hager GL. Corrigendum: Overlapping chromatin-remodeling systems collaborate genome wide at dynamic chromatin transitions Nature Structural & Molecular Biology. 21: 1106-1106. DOI: 10.1038/Nsmb1214-1106B |
0.332 |
|
2013 |
Kieffer-Kwon KR, Tang Z, Mathe E, Qian J, Sung MH, Li G, Resch W, Baek S, Pruett N, Grøntved L, Vian L, Nelson S, Zare H, Hakim O, Reyon D, ... ... Hager GL, et al. Interactome maps of mouse gene regulatory domains reveal basic principles of transcriptional regulation. Cell. 155: 1507-20. PMID 24360274 DOI: 10.1016/J.Cell.2013.11.039 |
0.423 |
|
2013 |
Lalmansingh AS, Arora K, Demarco RA, Hager GL, Nagaich AK. High-throughput RNA FISH analysis by imaging flow cytometry reveals that pioneer factor Foxa1 reduces transcriptional stochasticity. Plos One. 8: e76043. PMID 24073287 DOI: 10.1371/Journal.Pone.0076043 |
0.421 |
|
2013 |
Aguilar-Arnal L, Hakim O, Patel VR, Baldi P, Hager GL, Sassone-Corsi P. Cycles in spatial and temporal chromosomal organization driven by the circadian clock. Nature Structural & Molecular Biology. 20: 1206-13. PMID 24056944 DOI: 10.1038/Nsmb.2667 |
0.369 |
|
2013 |
Mousavi K, Zare H, Dell'orso S, Grontved L, Gutierrez-Cruz G, Derfoul A, Hager GL, Sartorelli V. eRNAs promote transcription by establishing chromatin accessibility at defined genomic loci. Molecular Cell. 51: 606-17. PMID 23993744 DOI: 10.1016/J.Molcel.2013.07.022 |
0.456 |
|
2013 |
Miranda TB, Voss TC, Hager GL. High-throughput fluorescence-based screen to identify factors involved in nuclear receptor recruitment to response elements. Methods in Molecular Biology (Clifton, N.J.). 1042: 3-12. PMID 23979996 DOI: 10.1007/978-1-62703-526-2_1 |
0.468 |
|
2013 |
He X, Chatterjee R, John S, Bravo H, Sathyanarayana BK, Biddie SC, FitzGerald PC, Stamatoyannopoulos JA, Hager GL, Vinson C. Contribution of nucleosome binding preferences and co-occurring DNA sequences to transcription factor binding. Bmc Genomics. 14: 428. PMID 23805837 DOI: 10.1186/1471-2164-14-428 |
0.442 |
|
2013 |
Miranda TB, Voss TC, Sung MH, Baek S, John S, Hawkins M, Grøntved L, Schiltz RL, Hager GL. Reprogramming the chromatin landscape: interplay of the estrogen and glucocorticoid receptors at the genomic level. Cancer Research. 73: 5130-9. PMID 23803465 DOI: 10.1158/0008-5472.Can-13-0742 |
0.414 |
|
2013 |
Nakahashi H, Kwon KR, Resch W, Vian L, Dose M, Stavreva D, Hakim O, Pruett N, Nelson S, Yamane A, Qian J, Dubois W, Welsh S, Phair RD, Pugh BF, ... ... Hager GL, et al. A genome-wide map of CTCF multivalency redefines the CTCF code. Cell Reports. 3: 1678-89. PMID 23707059 DOI: 10.1016/J.Celrep.2013.04.024 |
0.351 |
|
2013 |
Grøntved L, John S, Baek S, Liu Y, Buckley JR, Vinson C, Aguilera G, Hager GL. C/EBP maintains chromatin accessibility in liver and facilitates glucocorticoid receptor recruitment to steroid response elements. The Embo Journal. 32: 1568-83. PMID 23665916 DOI: 10.1038/Emboj.2013.106 |
0.477 |
|
2013 |
Miranda TB, Morris SA, Hager GL. Complex genomic interactions in the dynamic regulation of transcription by the glucocorticoid receptor. Molecular and Cellular Endocrinology. 380: 16-24. PMID 23499945 DOI: 10.1016/J.Mce.2013.03.002 |
0.483 |
|
2013 |
Hakim O, Sung MH, Nakayamada S, Voss TC, Baek S, Hager GL. Spatial congregation of STAT binding directs selective nuclear architecture during T-cell functional differentiation. Genome Research. 23: 462-72. PMID 23212947 DOI: 10.1101/Gr.147652.112 |
0.416 |
|
2013 |
Wiench M, Baek S, Hager G. Epigenetic modulation of distal regulatory elements in oral squamous cell carcinoma (OSCC). Clinical Epigenetics. 5: 1-1. DOI: 10.1186/1868-7083-5-S1-S3 |
0.394 |
|
2013 |
Hager GL. Reprogramming the chromain landscape at eukaryotic regulatory elements Epigenetics & Chromatin. 6: 1-1. DOI: 10.1186/1756-8935-6-S1-O20 |
0.441 |
|
2013 |
Grontved L, John S, Baek S, Liu Y, Buckley J, Vinson C, Aguilera G, Hager GL. Abstract 2314: The chromatin structure regulates selective glucocorticoid receptor recruitment to the genome in intact tissue. Cancer Research. 73: 2314-2314. DOI: 10.1158/1538-7445.Am2013-2314 |
0.46 |
|
2013 |
Miranda TB, Voss TC, Sung M, Baek S, John S, Hawkins M, Grontved L, Schiltz RL, Hager GL. Abstract 1075: Steroid receptor reprogramming of the chromatin landscape: crosstalk at the genomic level. Cancer Research. 73: 1075-1075. DOI: 10.1158/1538-7445.Am2013-1075 |
0.443 |
|
2012 |
Stavreva DA, George AA, Klausmeyer P, Varticovski L, Sack D, Voss TC, Schiltz RL, Blazer VS, Iwanowicz LR, Hager GL. Prevalent glucocorticoid and androgen activity in US water sources. Scientific Reports. 2: 937. PMID 23226835 DOI: 10.1038/Srep00937 |
0.321 |
|
2012 |
Khozoie C, Borland MG, Zhu B, Baek S, John S, Hager GL, Shah YM, Gonzalez FJ, Peters JM. Analysis of the peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) cistrome reveals novel co-regulatory role of ATF4. Bmc Genomics. 13: 665. PMID 23176727 DOI: 10.1186/1471-2164-13-665 |
0.414 |
|
2012 |
Grøntved L, Bandle R, John S, Baek S, Chung HJ, Liu Y, Aguilera G, Oberholtzer C, Hager GL, Levens D. Rapid genome-scale mapping of chromatin accessibility in tissue. Epigenetics & Chromatin. 5: 10. PMID 22734930 DOI: 10.1186/1756-8935-5-10 |
0.311 |
|
2012 |
Kovalchuk AL, Ansarah-Sobrinho C, Hakim O, Resch W, Tolarová H, Dubois W, Yamane A, Takizawa M, Klein I, Hager GL, Morse HC, Potter M, Nussenzweig MC, Casellas R. Mouse model of endemic Burkitt translocations reveals the long-range boundaries of Ig-mediated oncogene deregulation. Proceedings of the National Academy of Sciences of the United States of America. 109: 10972-7. PMID 22711821 DOI: 10.1073/Pnas.1200106109 |
0.433 |
|
2012 |
Mandrup S, Hager GL. Modulation of chromatin access during adipocyte differentiation. Nucleus (Austin, Tex.). 3: 12-5. PMID 22540022 DOI: 10.4161/Nucl.18928 |
0.399 |
|
2012 |
Stavreva DA, Varticovski L, Hager GL. Complex dynamics of transcription regulation. Biochimica Et Biophysica Acta. 1819: 657-66. PMID 22484099 DOI: 10.1016/J.Bbagrm.2012.03.004 |
0.442 |
|
2012 |
Romero OA, Setien F, John S, Gimenez-Xavier P, Gómez-López G, Pisano D, Condom E, Villanueva A, Hager GL, Sanchez-Cespedes M. The tumour suppressor and chromatin-remodelling factor BRG1 antagonizes Myc activity and promotes cell differentiation in human cancer. Embo Molecular Medicine. 4: 603-16. PMID 22407764 DOI: 10.1002/Emmm.201200236 |
0.355 |
|
2012 |
Hakim O, Resch W, Yamane A, Klein I, Kieffer-Kwon KR, Jankovic M, Oliveira T, Bothmer A, Voss TC, Ansarah-Sobrinho C, Mathe E, Liang G, Cobell J, Nakahashi H, Robbiani DF, ... ... Hager GL, et al. DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes. Nature. 484: 69-74. PMID 22314321 DOI: 10.1038/Nature10909 |
0.31 |
|
2012 |
Bhattacharyya N, Wiench M, Dumitrescu C, Connolly BM, Bugge TH, Patel HV, Gafni RI, Cherman N, Cho M, Hager GL, Collins MT. Mechanism of FGF23 processing in fibrous dysplasia. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 27: 1132-41. PMID 22247037 DOI: 10.1002/Jbmr.1546 |
0.306 |
|
2012 |
Baek S, Sung MH, Hager GL. Quantitative analysis of genome-wide chromatin remodeling. Methods in Molecular Biology (Clifton, N.J.). 833: 433-41. PMID 22183609 DOI: 10.1007/978-1-61779-477-3_26 |
0.425 |
|
2012 |
Grøntved L, Hager GL. Impact of chromatin structure on PR signaling: transition from local to global analysis. Molecular and Cellular Endocrinology. 357: 30-6. PMID 21958695 DOI: 10.1016/J.Mce.2011.09.006 |
0.473 |
|
2012 |
Conway-Campbell BL, Pooley JR, Hager GL, Lightman SL. Molecular dynamics of ultradian glucocorticoid receptor action. Molecular and Cellular Endocrinology. 348: 383-93. PMID 21872640 DOI: 10.1016/J.Mce.2011.08.014 |
0.376 |
|
2011 |
Nakayamada S, Kanno Y, Takahashi H, Jankovic D, Lu KT, Johnson TA, Sun HW, Vahedi G, Hakim O, Handon R, Schwartzberg PL, Hager GL, O'Shea JJ. Early Th1 cell differentiation is marked by a Tfh cell-like transition. Immunity. 35: 919-31. PMID 22195747 DOI: 10.1016/J.Immuni.2011.11.012 |
0.326 |
|
2011 |
Voss TC, Schiltz RL, Sung MH, Yen PM, Stamatoyannopoulos JA, Biddie SC, Johnson TA, Miranda TB, John S, Hager GL. Dynamic exchange at regulatory elements during chromatin remodeling underlies assisted loading mechanism. Cell. 146: 544-54. PMID 21835447 DOI: 10.1016/J.Cell.2011.07.006 |
0.485 |
|
2011 |
Biddie SC, John S, Sabo PJ, Thurman RE, Johnson TA, Schiltz RL, Miranda TB, Sung MH, Trump S, Lightman SL, Vinson C, Stamatoyannopoulos JA, Hager GL. Transcription factor AP1 potentiates chromatin accessibility and glucocorticoid receptor binding. Molecular Cell. 43: 145-55. PMID 21726817 DOI: 10.1016/J.Molcel.2011.06.016 |
0.518 |
|
2011 |
Wiench M, John S, Baek S, Johnson TA, Sung MH, Escobar T, Simmons CA, Pearce KH, Biddie SC, Sabo PJ, Thurman RE, Stamatoyannopoulos JA, Hager GL. DNA methylation status predicts cell type-specific enhancer activity. The Embo Journal. 30: 3028-39. PMID 21701563 DOI: 10.1038/Emboj.2011.210 |
0.462 |
|
2011 |
Conway-Campbell BL, George CL, Pooley JR, Knight DM, Norman MR, Hager GL, Lightman SL. The HSP90 molecular chaperone cycle regulates cyclical transcriptional dynamics of the glucocorticoid receptor and its coregulatory molecules CBP/p300 during ultradian ligand treatment. Molecular Endocrinology (Baltimore, Md.). 25: 944-54. PMID 21511880 DOI: 10.1210/Me.2010-0073 |
0.489 |
|
2011 |
Wiench M, Miranda TB, Hager GL. Control of nuclear receptor function by local chromatin structure. The Febs Journal. 278: 2211-30. PMID 21501385 DOI: 10.1111/J.1742-4658.2011.08126.X |
0.522 |
|
2011 |
Hakim O, Sung MH, Voss TC, Splinter E, John S, Sabo PJ, Thurman RE, Stamatoyannopoulos JA, de Laat W, Hager GL. Diverse gene reprogramming events occur in the same spatial clusters of distal regulatory elements. Genome Research. 21: 697-706. PMID 21471403 DOI: 10.1101/Gr.111153.110 |
0.461 |
|
2011 |
Siersbæk R, Nielsen R, John S, Sung MH, Baek S, Loft A, Hager GL, Mandrup S. Extensive chromatin remodelling and establishment of transcription factor 'hotspots' during early adipogenesis. The Embo Journal. 30: 1459-72. PMID 21427703 DOI: 10.1038/Emboj.2011.65 |
0.474 |
|
2011 |
John S, Sabo PJ, Thurman RE, Sung MH, Biddie SC, Johnson TA, Hager GL, Stamatoyannopoulos JA. Chromatin accessibility pre-determines glucocorticoid receptor binding patterns. Nature Genetics. 43: 264-8. PMID 21258342 DOI: 10.1038/Ng.759 |
0.438 |
|
2011 |
Qiu Y, Stavreva DA, Luo Y, Indrawan A, Chang M, Hager GL. Dynamic interaction of HDAC1 with a glucocorticoid receptor-regulated gene is modulated by the activity state of the promoter. The Journal of Biological Chemistry. 286: 7641-7. PMID 21127047 DOI: 10.1074/Jbc.M110.185488 |
0.444 |
|
2010 |
Dull A, Goncharova E, Hager G, McMahon JB. Development of an image analysis screen for estrogen receptor alpha (ERα) ligands through measurement of nuclear translocation dynamics. The Journal of Steroid Biochemistry and Molecular Biology. 122: 341-51. PMID 20816963 DOI: 10.1016/J.Jsbmb.2010.08.009 |
0.358 |
|
2010 |
Wiench M, Hager GL. Expanding horizons for nuclear receptors. Embo Reports. 11: 569-71. PMID 20634803 DOI: 10.1038/Embor.2010.111 |
0.387 |
|
2010 |
Hakim O, Sung MH, Hager GL. 3D shortcuts to gene regulation. Current Opinion in Cell Biology. 22: 305-13. PMID 20466532 DOI: 10.1016/J.Ceb.2010.04.005 |
0.406 |
|
2010 |
Zheng Y, John S, Pesavento JJ, Schultz-Norton JR, Schiltz RL, Baek S, Nardulli AM, Hager GL, Kelleher NL, Mizzen CA. Histone H1 phosphorylation is associated with transcription by RNA polymerases I and II. The Journal of Cell Biology. 189: 407-15. PMID 20439994 DOI: 10.1083/Jcb.201001148 |
0.331 |
|
2010 |
Sahu G, Wang D, Chen CB, Zhurkin VB, Harrington RE, Appella E, Hager GL, Nagaich AK. p53 binding to nucleosomal DNA depends on the rotational positioning of DNA response element. The Journal of Biological Chemistry. 285: 1321-32. PMID 19887449 DOI: 10.1074/Jbc.M109.081182 |
0.344 |
|
2010 |
Biddie SC, John S, Hager GL. Genome-wide mechanisms of nuclear receptor action. Trends in Endocrinology and Metabolism: Tem. 21: 3-9. PMID 19800253 DOI: 10.1016/J.Tem.2009.08.006 |
0.499 |
|
2010 |
Zach L, Hakim O, Sung MH, Hager G, Kevin C. Abstract 506: A time-dependent genome-wide gene interaction signature in U251 human glioma cell line exposed to ionizing radiation Cancer Research. 70: 506-506. DOI: 10.1158/1538-7445.Am10-506 |
0.331 |
|
2010 |
Romero-Ferraro OA, Gimenez-Xavier P, Morris S, Jhon S, Hager GL, Sanchez-Cespedes M. Abstract 1134: Analysis of the tumor supressor role of BRG1 in lung cancer Cancer Research. 70: 1134-1134. DOI: 10.1158/1538-7445.Am10-1134 |
0.339 |
|
2009 |
Luo Y, Jian W, Stavreva D, Fu X, Hager G, Bungert J, Huang S, Qiu Y. Trans-regulation of histone deacetylase activities through acetylation. The Journal of Biological Chemistry. 284: 34901-10. PMID 19822520 DOI: 10.1074/Jbc.M109.038356 |
0.436 |
|
2009 |
Sung MH, Salvatore L, De Lorenzi R, Indrawan A, Pasparakis M, Hager GL, Bianchi ME, Agresti A. Sustained oscillations of NF-kappaB produce distinct genome scanning and gene expression profiles. Plos One. 4: e7163. PMID 19787057 DOI: 10.1371/Journal.Pone.0007163 |
0.352 |
|
2009 |
Hager GL, McNally JG, Misteli T. Transcription dynamics. Molecular Cell. 35: 741-53. PMID 19782025 DOI: 10.1016/j.molcel.2009.09.005 |
0.328 |
|
2009 |
Stavreva DA, Wiench M, John S, Conway-Campbell BL, McKenna MA, Pooley JR, Johnson TA, Voss TC, Lightman SL, Hager GL. Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription. Nature Cell Biology. 11: 1093-102. PMID 19684579 DOI: 10.1038/Ncb1922 |
0.408 |
|
2009 |
Hager G. Footprints by deep sequencing. Nature Methods. 6: 254-5. PMID 19333240 DOI: 10.1038/Nmeth0409-254 |
0.337 |
|
2009 |
John S, Johnson TA, Sung MH, Biddie SC, Trump S, Koch-Paiz CA, Davis SR, Walker R, Meltzer PS, Hager GL. Kinetic complexity of the global response to glucocorticoid receptor action. Endocrinology. 150: 1766-74. PMID 19131569 DOI: 10.1210/En.2008-0863 |
0.396 |
|
2009 |
Voss TC, Schiltz RL, Sung MH, Johnson TA, John S, Hager GL. Combinatorial probabilistic chromatin interactions produce transcriptional heterogeneity. Journal of Cell Science. 122: 345-56. PMID 19126674 DOI: 10.1242/Jcs.035865 |
0.503 |
|
2009 |
Hakim O, John S, Ling JQ, Biddie SC, Hoffman AR, Hager GL. Glucocorticoid receptor activation of the Ciz1-Lcn2 locus by long range interactions. The Journal of Biological Chemistry. 284: 6048-52. PMID 19124469 DOI: 10.1074/Jbc.C800212200 |
0.448 |
|
2009 |
Biddie SC, Hager GL. Glucocorticoid receptor dynamics and gene regulation. Stress (Amsterdam, Netherlands). 12: 193-205. PMID 19051126 DOI: 10.1080/10253890802506409 |
0.424 |
|
2009 |
George AA, Schiltz RL, Hager GL. Dynamic access of the glucocorticoid receptor to response elements in chromatin. The International Journal of Biochemistry & Cell Biology. 41: 214-24. PMID 18930837 DOI: 10.1016/J.Biocel.2008.09.019 |
0.505 |
|
2008 |
Sung MH, Bagain L, Chen Z, Karpova T, Yang X, Silvin C, Voss TC, McNally JG, Van Waes C, Hager GL. Dynamic effect of bortezomib on nuclear factor-kappaB activity and gene expression in tumor cells. Molecular Pharmacology. 74: 1215-22. PMID 18684839 DOI: 10.1124/Mol.108.049114 |
0.343 |
|
2008 |
Voss TC, Hager GL. Visualizing chromatin dynamics in intact cells. Biochimica Et Biophysica Acta. 1783: 2044-51. PMID 18675855 DOI: 10.1016/J.Bbamcr.2008.06.022 |
0.493 |
|
2008 |
Johnson TA, Elbi C, Parekh BS, Hager GL, John S. Chromatin remodeling complexes interact dynamically with a glucocorticoid receptor-regulated promoter. Molecular Biology of the Cell. 19: 3308-22. PMID 18508913 DOI: 10.1091/Mbc.E08-02-0123 |
0.478 |
|
2008 |
John S, Sabo PJ, Johnson TA, Sung MH, Biddie SC, Lightman SL, Voss TC, Davis SR, Meltzer PS, Stamatoyannopoulos JA, Hager GL. Interaction of the glucocorticoid receptor with the chromatin landscape. Molecular Cell. 29: 611-24. PMID 18342607 DOI: 10.1016/J.Molcel.2008.02.010 |
0.499 |
|
2007 |
Dundr M, Ospina JK, Sung MH, John S, Upender M, Ried T, Hager GL, Matera AG. Actin-dependent intranuclear repositioning of an active gene locus in vivo. The Journal of Cell Biology. 179: 1095-103. PMID 18070915 DOI: 10.1083/Jcb.200710058 |
0.39 |
|
2007 |
Meijsing SH, Elbi C, Luecke HF, Hager GL, Yamamoto KR. The ligand binding domain controls glucocorticoid receptor dynamics independent of ligand release. Molecular and Cellular Biology. 27: 2442-51. PMID 17261597 DOI: 10.1128/Mcb.01570-06 |
0.41 |
|
2007 |
Klokk TI, Kurys P, Elbi C, Nagaich AK, Hendarwanto A, Slagsvold T, Chang CY, Hager GL, Saatcioglu F. Ligand-specific dynamics of the androgen receptor at its response element in living cells. Molecular and Cellular Biology. 27: 1823-43. PMID 17189428 DOI: 10.1128/Mcb.01297-06 |
0.458 |
|
2007 |
Huh JI, Qiu TH, Chandramouli GV, Charles R, Wiench M, Hager GL, Catena R, Calvo A, LaVallee TM, Desprez PY, Green JE. 2-methoxyestradiol induces mammary gland differentiation through amphiregulin-epithelial growth factor receptor-mediated signaling: molecular distinctions from the mammary gland of pregnant mice. Endocrinology. 148: 1266-77. PMID 17158205 DOI: 10.1210/En.2006-0964 |
0.353 |
|
2006 |
Martinez ED, Hager GL. Development of assays for nuclear receptor modulators using fluorescently tagged proteins. Methods in Enzymology. 414: 37-50. PMID 17110185 DOI: 10.1016/S0076-6879(06)14003-3 |
0.407 |
|
2006 |
Martinez ED, Dull AB, Beutler JA, Hager GL. High-content fluorescence-based screening for epigenetic modulators. Methods in Enzymology. 414: 21-36. PMID 17110184 DOI: 10.1016/S0076-6879(06)14002-1 |
0.372 |
|
2006 |
Bash R, Wang H, Anderson C, Yodh J, Hager G, Lindsay SM, Lohr D. AFM imaging of protein movements: histone H2A-H2B release during nucleosome remodeling. Febs Letters. 580: 4757-61. PMID 16876789 DOI: 10.1016/J.Febslet.2006.06.101 |
0.342 |
|
2006 |
Voss TC, John S, Hager GL. Single-cell analysis of glucocorticoid receptor action reveals that stochastic post-chromatin association mechanisms regulate ligand-specific transcription. Molecular Endocrinology (Baltimore, Md.). 20: 2641-55. PMID 16873444 DOI: 10.1210/Me.2006-0091 |
0.451 |
|
2006 |
Qiu Y, Zhao Y, Becker M, John S, Parekh BS, Huang S, Hendarwanto A, Martinez ED, Chen Y, Lu H, Adkins NL, Stavreva DA, Wiench M, Georgel PT, Schiltz RL, ... Hager GL, et al. HDAC1 acetylation is linked to progressive modulation of steroid receptor-induced gene transcription. Molecular Cell. 22: 669-79. PMID 16762839 DOI: 10.1016/J.Molcel.2006.04.019 |
0.457 |
|
2006 |
Marom R, Shur I, Hager GL, Benayahu D. Expression and regulation of CReMM, a chromodomain helicase-DNA-binding (CHD), in marrow stroma derived osteoprogenitors. Journal of Cellular Physiology. 207: 628-35. PMID 16523501 DOI: 10.1002/Jcp.20611 |
0.344 |
|
2006 |
Hager GL, Elbi C, Johnson TA, Voss T, Nagaich AK, Schiltz RL, Qiu Y, John S. Chromatin dynamics and the evolution of alternate promoter states. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 14: 107-16. PMID 16506100 DOI: 10.1007/S10577-006-1030-0 |
0.481 |
|
2005 |
Martinez ED, Rayasam GV, Dull AB, Walker DA, Hager GL. An estrogen receptor chimera senses ligands by nuclear translocation. The Journal of Steroid Biochemistry and Molecular Biology. 97: 307-21. PMID 16162406 DOI: 10.1016/J.Jsbmb.2005.06.033 |
0.379 |
|
2005 |
Becker M, Becker A, Miyara F, Han Z, Kihara M, Brown DT, Hager GL, Latham K, Adashi EY, Misteli T. Differential in vivo binding dynamics of somatic and oocyte-specific linker histones in oocytes and during ES cell nuclear transfer. Molecular Biology of the Cell. 16: 3887-95. PMID 15944219 DOI: 10.1091/Mbc.E05-04-0350 |
0.44 |
|
2005 |
Rayasam GV, Elbi C, Walker DA, Wolford R, Fletcher TM, Edwards DP, Hager GL. Ligand-specific dynamics of the progesterone receptor in living cells and during chromatin remodeling in vitro. Molecular and Cellular Biology. 25: 2406-18. PMID 15743833 DOI: 10.1128/Mcb.25.6.2406-2418.2005 |
0.488 |
|
2004 |
Nagaich AK, Hager GL. UV laser cross-linking: a real-time assay to study dynamic protein/DNA interactions during chromatin remodeling. Science's Stke : Signal Transduction Knowledge Environment. 2004: pl13. PMID 15507594 DOI: 10.1126/Stke.2562004Pl13 |
0.402 |
|
2004 |
Wang H, Bash R, Yodh JG, Hager G, Lindsay SM, Lohr D. Using atomic force microscopy to study nucleosome remodeling on individual nucleosomal arrays in situ. Biophysical Journal. 87: 1964-71. PMID 15345572 DOI: 10.1529/Biophysj.104.042606 |
0.403 |
|
2004 |
Robertson AK, Geiman TM, Sankpal UT, Hager GL, Robertson KD. Effects of chromatin structure on the enzymatic and DNA binding functions of DNA methyltransferases DNMT1 and Dnmt3a in vitro. Biochemical and Biophysical Research Communications. 322: 110-8. PMID 15313181 DOI: 10.1016/J.Bbrc.2004.07.083 |
0.396 |
|
2004 |
Nagaich AK, Rayasam GV, Martinez ED, Becker M, Qiu Y, Johnson TA, Elbi C, Fletcher TM, John S, Hager GL. Subnuclear trafficking and gene targeting by steroid receptors. Annals of the New York Academy of Sciences. 1024: 213-20. PMID 15265783 DOI: 10.1196/Annals.1321.002 |
0.515 |
|
2004 |
Phair RD, Scaffidi P, Elbi C, Vecerová J, Dey A, Ozato K, Brown DT, Hager G, Bustin M, Misteli T. Global nature of dynamic protein-chromatin interactions in vivo: three-dimensional genome scanning and dynamic interaction networks of chromatin proteins. Molecular and Cellular Biology. 24: 6393-402. PMID 15226439 DOI: 10.1128/Mcb.24.14.6393-6402.2004 |
0.411 |
|
2004 |
Elbi C, Walker DA, Lewis M, Romero G, Sullivan WP, Toft DO, Hager GL, DeFranco DB. A novel in situ assay for the identification and characterization of soluble nuclear mobility factors. Science's Stke : Signal Transduction Knowledge Environment. 2004: pl10. PMID 15213337 DOI: 10.1126/Stke.2382004Pl10 |
0.353 |
|
2004 |
Nagaich AK, Walker DA, Wolford R, Hager GL. Rapid periodic binding and displacement of the glucocorticoid receptor during chromatin remodeling. Molecular Cell. 14: 163-74. PMID 15099516 DOI: 10.1016/S1097-2765(04)00178-9 |
0.489 |
|
2004 |
Knockaert M, Blondel M, Bach S, Leost M, Elbi C, Hager GL, Nagy SR, Han D, Denison M, Ffrench M, Ryan XP, Magiatis P, Polychronopoulos P, Greengard P, Skaltsounis L, et al. Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the antiproliferative effects of indirubins. Oncogene. 23: 4400-12. PMID 15077192 DOI: 10.1038/Sj.Onc.1207535 |
0.327 |
|
2004 |
Stavreva DA, Müller WG, Hager GL, Smith CL, McNally JG. Rapid glucocorticoid receptor exchange at a promoter is coupled to transcription and regulated by chaperones and proteasomes. Molecular and Cellular Biology. 24: 2682-97. PMID 15024059 DOI: 10.1128/Mcb.24.7.2682-2697.2004 |
0.472 |
|
2004 |
Hager GL, Nagaich AK, Johnson TA, Walker DA, John S. Dynamics of nuclear receptor movement and transcription. Biochimica Et Biophysica Acta. 1677: 46-51. PMID 15020044 DOI: 10.1016/J.Bbaexp.2003.09.016 |
0.497 |
|
2004 |
Elbi C, Walker DA, Romero G, Sullivan WP, Toft DO, Hager GL, DeFranco DB. Molecular chaperones function as steroid receptor nuclear mobility factors. Proceedings of the National Academy of Sciences of the United States of America. 101: 2876-81. PMID 14978266 DOI: 10.1073/Pnas.0400116101 |
0.43 |
|
2004 |
Dohoney KM, Guillerm C, Whiteford C, Elbi C, Lambert PF, Hager GL, Brady JN. Phosphorylation of p53 at serine 37 is important for transcriptional activity and regulation in response to DNA damage. Oncogene. 23: 49-57. PMID 14712210 DOI: 10.1038/Sj.Onc.1207005 |
0.338 |
|
2004 |
Dent SR, Hager GL. Robert T. Simpson (1938–2004) Molecular Cell. 15: 3-4. DOI: 10.1016/J.Molcel.2004.06.027 |
0.362 |
|
2003 |
Georgel PT, Fletcher TM, Hager GL, Hansen JC. Formation of higher-order secondary and tertiary chromatin structures by genomic mouse mammary tumor virus promoters. Genes & Development. 17: 1617-29. PMID 12842912 DOI: 10.1101/Gad.1097603 |
0.464 |
|
2003 |
Rayasam GV, Wendling O, Angrand PO, Mark M, Niederreither K, Song L, Lerouge T, Hager GL, Chambon P, Losson R. NSD1 is essential for early post-implantation development and has a catalytically active SET domain. The Embo Journal. 22: 3153-63. PMID 12805229 DOI: 10.1093/Emboj/Cdg288 |
0.363 |
|
2003 |
Bash R, Wang H, Yodh J, Hager G, Lindsay SM, Lohr D. Nucleosomal arrays can be salt-reconstituted on a single-copy MMTV promoter DNA template: their properties differ in several ways from those of comparable 5S concatameric arrays. Biochemistry. 42: 4681-90. PMID 12705831 DOI: 10.1021/Bi026887O |
0.342 |
|
2003 |
Maruvada P, Baumann CT, Hager GL, Yen PM. Dynamic shuttling and intranuclear mobility of nuclear hormone receptors. The Journal of Biological Chemistry. 278: 12425-32. PMID 12506123 DOI: 10.1074/Jbc.M202752200 |
0.384 |
|
2002 |
Wang H, Bash R, Yodh JG, Hager GL, Lohr D, Lindsay SM. Glutaraldehyde modified mica: a new surface for atomic force microscopy of chromatin. Biophysical Journal. 83: 3619-25. PMID 12496129 DOI: 10.1016/S0006-3495(02)75362-9 |
0.326 |
|
2002 |
Becker M, Baumann C, John S, Walker DA, Vigneron M, McNally JG, Hager GL. Dynamic behavior of transcription factors on a natural promoter in living cells. Embo Reports. 3: 1188-94. PMID 12446572 DOI: 10.1093/Embo-Reports/Kvf244 |
0.442 |
|
2002 |
Elbi C, Misteli T, Hager GL. Recruitment of dioxin receptor to active transcription sites. Molecular Biology of the Cell. 13: 2001-15. PMID 12058065 DOI: 10.1091/Mboc.13.6.Mk0602002001 |
0.476 |
|
2002 |
Lu H, Pise-Masison CA, Fletcher TM, Schiltz RL, Nagaich AK, Radonovich M, Hager G, Cole PA, Brady JN. Acetylation of nucleosomal histones by p300 facilitates transcription from tax-responsive human T-cell leukemia virus type 1 chromatin template. Molecular and Cellular Biology. 22: 4450-62. PMID 12052856 DOI: 10.1128/Mcb.22.13.4450-4462.2002 |
0.46 |
|
2002 |
Keeton EK, Fletcher TM, Baumann CT, Hager GL, Smith CL. Glucocorticoid receptor domain requirements for chromatin remodeling and transcriptional activation of the mouse mammary tumor virus promoter in different nucleoprotein contexts. The Journal of Biological Chemistry. 277: 28247-55. PMID 12029095 DOI: 10.1074/Jbc.M203898200 |
0.766 |
|
2002 |
Fletcher TM, Xiao N, Mautino G, Baumann CT, Wolford R, Warren BS, Hager GL. ATP-dependent mobilization of the glucocorticoid receptor during chromatin remodeling. Molecular and Cellular Biology. 22: 3255-63. PMID 11971959 DOI: 10.1128/Mcb.22.10.3255-3263.2002 |
0.53 |
|
2002 |
Akiyama TE, Baumann CT, Sakai S, Hager GL, Gonzalez FJ. Selective intranuclear redistribution of PPAR isoforms by RXR alpha. Molecular Endocrinology (Baltimore, Md.). 16: 707-21. PMID 11923467 DOI: 10.1210/Mend.16.4.0797 |
0.412 |
|
2002 |
Hager GL, Elbi C, Becker M. Protein dynamics in the nuclear compartment. Current Opinion in Genetics & Development. 12: 137-41. PMID 11893485 DOI: 10.1016/S0959-437X(02)00278-2 |
0.388 |
|
2002 |
Lu H, Pise-Masison CA, Fletcher TM, Schiltz RL, Nagaich AK, Radonovich M, Hager G, Cole PA, Brady JN. Acetylation of Nucleosomal Histones by p300 Facilitates Transcriptionfrom Tax-Responsive Human T-Cell Leukemia Virus Type 1Chromatin Template Molecular and Cellular Biology. 22: 6930-6930. DOI: 10.1128/Mcb.22.19.6930.2002 |
0.345 |
|
2001 |
Ma H, Baumann CT, Li H, Strahl BD, Rice R, Jelinek MA, Aswad DW, Allis CD, Hager GL, Stallcup MR. Hormone-dependent, CARM1-directed, arginine-specific methylation of histone H3 on a steroid-regulated promoter. Current Biology : Cb. 11: 1981-5. PMID 11747826 DOI: 10.1016/S0960-9822(01)00600-5 |
0.465 |
|
2001 |
Mackem S, Baumann CT, Hager GL. A glucocorticoid/retinoic acid receptor chimera that displays cytoplasmic/nuclear translocation in response to retinoic acid. A real time sensing assay for nuclear receptor ligands. The Journal of Biological Chemistry. 276: 45501-4. PMID 11585812 DOI: 10.1074/Jbc.C100269200 |
0.406 |
|
2001 |
Fletcher TM, Warren BS, Baumann CT, Hager GL. High-yield purification of functionally active glucocorticoid receptor. Methods in Molecular Biology (Clifton, N.J.). 176: 55-65. PMID 11554338 DOI: 10.1385/1-59259-115-9:55 |
0.328 |
|
2001 |
Müller WG, Walker D, Hager GL, McNally JG. Large-scale chromatin decondensation and recondensation regulated by transcription from a natural promoter. The Journal of Cell Biology. 154: 33-48. PMID 11448988 DOI: 10.1083/Jcb.200011069 |
0.461 |
|
2001 |
Hager G. Alan Wolffe (1959-2001). Cell. 105: 849-50. PMID 11439181 DOI: 10.1016/S0092-8674(01)00413-5 |
0.39 |
|
2001 |
Baumann CT, Ma H, Wolford R, Reyes JC, Maruvada P, Lim C, Yen PM, Stallcup MR, Hager GL. The glucocorticoid receptor interacting protein 1 (GRIP1) localizes in discrete nuclear foci that associate with ND10 bodies and are enriched in components of the 26S proteasome. Molecular Endocrinology (Baltimore, Md.). 15: 485-500. PMID 11266502 DOI: 10.1210/Mend.15.4.0618 |
0.416 |
|
2001 |
Baumann CT, Maruvada P, Hager GL, Yen PM. Nuclear cytoplasmic shuttling by thyroid hormone receptors. multiple protein interactions are required for nuclear retention. The Journal of Biological Chemistry. 276: 11237-45. PMID 11152480 DOI: 10.1074/Jbc.M011112200 |
0.428 |
|
2000 |
Hager GL, Lim CS, Elbi C, Baumann CT. Trafficking of nuclear receptors in living cells. The Journal of Steroid Biochemistry and Molecular Biology. 74: 249-54. PMID 11162932 DOI: 10.1016/S0960-0760(00)00100-X |
0.41 |
|
2000 |
Fletcher TM, Ryu BW, Baumann CT, Warren BS, Fragoso G, John S, Hager GL. Structure and dynamic properties of a glucocorticoid receptor-induced chromatin transition. Molecular and Cellular Biology. 20: 6466-75. PMID 10938123 DOI: 10.1128/Mcb.20.17.6466-6475.2000 |
0.484 |
|
2000 |
Smith CL, Wolford RG, O'Neill TB, Hager GL. Characterization of transiently and constitutively expressed progesterone receptors: evidence for two functional states. Molecular Endocrinology (Baltimore, Md.). 14: 956-71. PMID 10894147 DOI: 10.1210/Mend.14.7.0482 |
0.439 |
|
2000 |
McNally JG, Müller WG, Walker D, Wolford R, Hager GL. The glucocorticoid receptor: rapid exchange with regulatory sites in living cells. Science (New York, N.Y.). 287: 1262-5. PMID 10678832 DOI: 10.1126/Science.287.5456.1262 |
0.47 |
|
2000 |
Hager GL, McNally JG, Müller WG, Ryu BW, Baumann CT, Fletcher TM. Dynamics of Steroid Receptor Interaction with Chromosomal Targets Biochemical Society Transactions. 28. DOI: 10.1042/Bst028A064A |
0.315 |
|
2000 |
Hager GL, Fletcher TM, Xiao N, Baumann CT, Müller WG, McNally JG. Dynamics of gene targeting and chromatin remodelling by nuclear receptors Biochemical Society Transactions. 28: 405-410. DOI: 10.1042/Bst0280405 |
0.523 |
|
1999 |
Hager GL. Studying nuclear receptors with green fluorescent protein fusions. Methods in Enzymology. 302: 73-84. PMID 12876764 DOI: 10.1016/S0076-6879(99)02011-X |
0.396 |
|
1999 |
Baumann CT, Lim CS, Hager GL. Intracellular localization and trafficking of steroid receptors. Cell Biochemistry and Biophysics. 31: 119-27. PMID 10593254 DOI: 10.1007/Bf02738167 |
0.311 |
|
1999 |
Walker D, Htun H, Hager GL. Using inducible vectors to study intracellular trafficking of GFP-tagged steroid/nuclear receptors in living cells. Methods (San Diego, Calif.). 19: 386-93. PMID 10579933 DOI: 10.1006/Meth.1999.0874 |
0.389 |
|
1999 |
Hager G. Methods issue on nuclear structure and chromatin. Methods (San Diego, Calif.). 19: 351-2. PMID 10579929 DOI: 10.1006/Meth.1999.0870 |
0.322 |
|
1999 |
Sheldon LA, Smith CL, Bodwell JE, Munck AU, Hager GL. A ligand binding domain mutation in the mouse glucocorticoid receptor functionally links chromatin remodeling and transcription initiation. Molecular and Cellular Biology. 19: 8146-57. PMID 10567540 DOI: 10.1128/Mcb.19.12.8146 |
0.467 |
|
1999 |
Kramer PR, Fragoso G, Pennie W, Htun H, Hager GL, Sinden RR. Transcriptional state of the mouse mammary tumor virus promoter can affect topological domain size in vivo. The Journal of Biological Chemistry. 274: 28590-7. PMID 10497225 DOI: 10.1074/Jbc.274.40.28590 |
0.388 |
|
1999 |
Hager GL, Fragoso G. Analysis of nucleosome positioning in mammalian cells. Methods in Enzymology. 304: 626-38. PMID 10372386 DOI: 10.1016/S0076-6879(99)04037-9 |
0.364 |
|
1999 |
Lim CS, Baumann CT, Htun H, Xian W, Irie M, Smith CL, Hager GL. Differential localization and activity of the A- and B-forms of the human progesterone receptor using green fluorescent protein chimeras. Molecular Endocrinology (Baltimore, Md.). 13: 366-75. PMID 10076994 DOI: 10.1210/Mend.13.3.0247 |
0.402 |
|
1999 |
Htun H, Holth LT, Walker D, Davie JR, Hager GL. Direct visualization of the human estrogen receptor alpha reveals a role for ligand in the nuclear distribution of the receptor. Molecular Biology of the Cell. 10: 471-86. PMID 9950689 DOI: 10.1091/Mbc.10.2.471 |
0.38 |
|
1999 |
Chandran UR, Warren BS, Baumann CT, Hager GL, DeFranco DB. The glucocorticoid receptor is tethered to DNA-bound Oct-1 at the mouse gonadotropin-releasing hormone distal negative glucocorticoid response element. The Journal of Biological Chemistry. 274: 2372-8. PMID 9891005 DOI: 10.1074/Jbc.274.4.2372 |
0.483 |
|
1998 |
Zhu XG, Hanover JA, Hager GL, Cheng SY. Hormone-induced translocation of thyroid hormone receptors in living cells visualized using a receptor green fluorescent protein chimera. The Journal of Biological Chemistry. 273: 27058-63. PMID 9765220 DOI: 10.1074/jbc.273.42.27058 |
0.311 |
|
1998 |
Hager GL, Smith CL, Fragoso G, Wolford R, Walker D, Barsony J, Htun H. Intranuclear trafficking and gene targeting by members of the steroid/nuclear receptor superfamily. The Journal of Steroid Biochemistry and Molecular Biology. 65: 125-32. PMID 9699865 DOI: 10.1016/S0960-0760(97)00178-7 |
0.495 |
|
1998 |
Fragoso G, Pennie WD, John S, Hager GL. The position and length of the steroid-dependent hypersensitive region in the mouse mammary tumor virus long terminal repeat are invariant despite multiple nucleosome B frames. Molecular and Cellular Biology. 18: 3633-44. PMID 9584204 DOI: 10.1128/Mcb.18.6.3633 |
0.392 |
|
1998 |
Myers CA, Schmidhauser C, Mellentin-Michelotti J, Fragoso G, Roskelley CD, Casperson G, Mossi R, Pujuguet P, Hager G, Bissell MJ. Characterization of BCE-1, a transcriptional enhancer regulated by prolactin and extracellular matrix and modulated by the state of histone acetylation. Molecular and Cellular Biology. 18: 2184-95. PMID 9528790 DOI: 10.1128/Mcb.18.4.2184 |
0.481 |
|
1997 |
Smith CL, Hager GL. Transcriptional regulation of mammalian genes in vivo. A tale of two templates. The Journal of Biological Chemistry. 272: 27493-6. PMID 9346875 DOI: 10.1074/Jbc.272.44.27493 |
0.41 |
|
1997 |
Bhattacharyya N, Dey A, Minucci S, Zimmer A, John S, Hager G, Ozato K. Retinoid-induced chromatin structure alterations in the retinoic acid receptor beta2 promoter. Molecular and Cellular Biology. 17: 6481-90. PMID 9343411 DOI: 10.1128/Mcb.17.11.6481 |
0.401 |
|
1997 |
Smith CL, Htun H, Wolford RG, Hager GL. Differential activity of progesterone and glucocorticoid receptors on mouse mammary tumor virus templates differing in chromatin structure. The Journal of Biological Chemistry. 272: 14227-35. PMID 9162055 DOI: 10.1074/Jbc.272.22.14227 |
0.498 |
|
1997 |
Fragoso G, Hager GL. Analysis of in vivo nucleosome positions by determination of nucleosome-linker boundaries in crosslinked chromatin. Methods (San Diego, Calif.). 11: 246-52. PMID 8993037 DOI: 10.1006/Meth.1996.0411 |
0.32 |
|
1996 |
Kusk P, John S, Fragoso G, Michelotti J, Hager GL. Characterization of an NF-1/CTF family member as a functional activator of the mouse mammary tumor virus long terminal repeat 5' enhancer. The Journal of Biological Chemistry. 271: 31269-76. PMID 8940131 DOI: 10.1074/Jbc.271.49.31269 |
0.382 |
|
1996 |
Htun H, Barsony J, Renyi I, Gould DL, Hager GL. Visualization of glucocorticoid receptor translocation and intranuclear organization in living cells with a green fluorescent protein chimera. Proceedings of the National Academy of Sciences of the United States of America. 93: 4845-50. PMID 8643491 DOI: 10.1073/Pnas.93.10.4845 |
0.414 |
|
1996 |
Warren BS, Kusk P, Wolford RG, Hager GL. Purification and stabilization of transcriptionally active glucocorticoid receptor. The Journal of Biological Chemistry. 271: 11434-40. PMID 8626700 DOI: 10.1074/Jbc.271.19.11434 |
0.397 |
|
1995 |
Pennie WD, Hager GL, Smith CL. Nucleoprotein structure influences the response of the mouse mammary tumor virus promoter to activation of the cyclic AMP signalling pathway. Molecular and Cellular Biology. 15: 2125-34. PMID 7891707 DOI: 10.1128/Mcb.15.4.2125 |
0.445 |
|
1995 |
Mymryk JS, Berard D, Hager GL, Archer TK. Mouse mammary tumor virus chromatin in human breast cancer cells is constitutively hypersensitive and exhibits steroid hormone-independent loading of transcription factors in vivo. Molecular and Cellular Biology. 15: 26-34. PMID 7799933 DOI: 10.1128/MCB.15.1.26 |
0.361 |
|
1995 |
Nobukuni Y, Smith CL, Hager GL, Detera-Wadleigh SD. Characterization of the human glucocorticoid receptor promoter. Biochemistry. 34: 8207-14. PMID 7794935 DOI: 10.1021/Bi00025A028 |
0.458 |
|
1995 |
Fragoso G, John S, Roberts MS, Hager GL. Nucleosome positioning on the MMTV LTR results from the frequency-biased occupancy of multiple frames. Genes & Development. 9: 1933-47. PMID 7649476 DOI: 10.1101/Gad.9.15.1933 |
0.33 |
|
1995 |
Kusk P, Carlson KE, Warren BS, Hager GL. Role of the TATA box in transcription of the mouse mammary tumor virus long terminal repeat. Molecular Endocrinology (Baltimore, Md.). 9: 1180-92. PMID 7491110 DOI: 10.1210/Mend.9.9.7491110 |
0.471 |
|
1994 |
Archer TK, Lee HL, Cordingley MG, Mymryk JS, Fragoso G, Berard DS, Hager GL. Differential steroid hormone induction of transcription from the mouse mammary tumor virus promoter. Molecular Endocrinology (Baltimore, Md.). 8: 568-76. PMID 8058066 DOI: 10.1210/Mend.8.5.8058066 |
0.451 |
|
1993 |
Smith CL, Archer TK, Hamlin-Green G, Hager GL. Newly expressed progesterone receptor cannot activate stable, replicated mouse mammary tumor virus templates but acquires transactivation potential upon continuous expression. Proceedings of the National Academy of Sciences of the United States of America. 90: 11202-6. PMID 8248228 DOI: 10.1073/Pnas.90.23.11202 |
0.464 |
|
1993 |
Hager GL, Archer TK, Fragoso G, Bresnick EH, Tsukagoshi Y, John S, Smith CL. Influence of chromatin structure on the binding of transcription factors to DNA. Cold Spring Harbor Symposia On Quantitative Biology. 58: 63-71. PMID 7956078 DOI: 10.1101/Sqb.1993.058.01.010 |
0.423 |
|
1992 |
Archer TK, Lefebvre P, Wolford RG, Hager GL. Transcription factor loading on the MMTV promoter: a bimodal mechanism for promoter activation. Science (New York, N.Y.). 255: 1573-6. PMID 1347958 DOI: 10.1126/Science.1347958 |
0.486 |
|
1992 |
Bresnick EH, Rories C, Hager GL. Evidence that nucleosomes on the mouse mammary tumor virus promoter adopt specific translational positions. Nucleic Acids Research. 20: 865-70. PMID 1311832 DOI: 10.1093/Nar/20.4.865 |
0.431 |
|
1992 |
Bresnick EH, Bustin M, Marsaud V, Richard-Foy H, Hager GL. The transcriptionally-active MMTV promoter is depleted of histone H1. Nucleic Acids Research. 20: 273-8. PMID 1311071 DOI: 10.1093/Nar/20.2.273 |
0.436 |
|
1991 |
Bresnick EH, John S, Hager GL. Histone hyperacetylation does not alter the positioning or stability of phased nucleosomes on the mouse mammary tumor virus long terminal repeat. Biochemistry. 30: 3490-7. PMID 1849427 DOI: 10.1021/Bi00228A020 |
0.426 |
|
1991 |
Archer TK, Cordingley MG, Wolford RG, Hager GL. Transcription factor access is mediated by accurately positioned nucleosomes on the mouse mammary tumor virus promoter. Molecular and Cellular Biology. 11: 688-98. PMID 1846670 DOI: 10.1128/Mcb.11.2.688 |
0.504 |
|
1991 |
Riegel AT, Lu Y, Remenick J, Wolford RG, Berard DS, Hager GL. Proopiomelanocortin gene promoter elements required for constitutive and glucocorticoid-repressed transcription. Molecular Endocrinology (Baltimore, Md.). 5: 1973-82. PMID 1791842 DOI: 10.1210/Mend-5-12-1973 |
0.437 |
|
1991 |
Lefebvre P, Berard DS, Cordingley MG, Hager GL. Two regions of the mouse mammary tumor virus long terminal repeat regulate the activity of its promoter in mammary cell lines. Molecular and Cellular Biology. 11: 2529-37. PMID 1708094 DOI: 10.1128/Mcb.11.5.2529 |
0.432 |
|
1991 |
Smith CL, Hager GL, Pike JW, Marx SJ. Overexpression of the human vitamin D3 receptor in mammalian cells using recombinant adenovirus vectors. Molecular Endocrinology (Baltimore, Md.). 5: 867-78. PMID 1656244 DOI: 10.1210/Mend-5-6-867 |
0.369 |
|
1990 |
Riegel AT, Remenick J, Wolford RG, Berard DS, Hager GL. A novel transcriptional activator (PO-B) binds between the TATA box and cap site of the pro-opiomelanocortin gene. Nucleic Acids Research. 18: 4513-21. PMID 2388831 DOI: 10.1093/Nar/18.15.4513 |
0.438 |
|
1990 |
Bresnick EH, John S, Berard DS, LeFebvre P, Hager GL. Glucocorticoid receptor-dependent disruption of a specific nucleosome on the mouse mammary tumor virus promoter is prevented by sodium butyrate. Proceedings of the National Academy of Sciences of the United States of America. 87: 3977-81. PMID 2160080 DOI: 10.1073/Pnas.87.10.3977 |
0.513 |
|
1990 |
Archer TK, Hager GL, Omichinski JG. Sequence-specific DNA binding by glucocorticoid receptor "zinc finger peptides". Proceedings of the National Academy of Sciences of the United States of America. 87: 7560-4. PMID 2120703 DOI: 10.1073/Pnas.87.19.7560 |
0.373 |
|
1989 |
Charron J, Richard-Foy H, Berard DS, Hager GL, Drouin J. Independent glucocorticoid induction and repression of two contiguous responsive genes. Molecular and Cellular Biology. 9: 3127-31. PMID 2550796 DOI: 10.1128/Mcb.9.7.3127 |
0.481 |
|
1988 |
Cordingley MG, Hager GL. Binding of multiple factors to the MMTV promoter in crude and fractionated nuclear extracts. Nucleic Acids Research. 16: 609-28. PMID 2829133 DOI: 10.1093/Nar/16.2.609 |
0.434 |
|
1987 |
Sistare FD, Hager GL, Simons SS. Mechanism of dexamethasone 21-mesylate antiglucocorticoid action: I. Receptor-antiglucocorticoid complexes do not competitively inhibit receptor-glucocorticoid complex activation of gene transcription in vivo. Molecular Endocrinology (Baltimore, Md.). 1: 648-58. PMID 3153481 DOI: 10.1210/Mend-1-9-648 |
0.431 |
|
1987 |
Cordingley MG, Riegel AT, Hager GL. Steroid-dependent interaction of transcription factors with the inducible promoter of mouse mammary tumor virus in vivo. Cell. 48: 261-70. PMID 3026639 DOI: 10.1016/0092-8674(87)90429-6 |
0.454 |
|
1987 |
Richard-Foy H, Sistare FD, Riegel AT, Simons SS, Hager GL. Mechanism of dexamethasone 21-mesylate antiglucocorticoid action: II. Receptor-antiglucocorticoid complexes do not interact productively with mouse mammary tumor virus long terminal repeat chromatin. Molecular Endocrinology (Baltimore, Md.). 1: 659-65. PMID 2856414 DOI: 10.1210/Mend-1-9-659 |
0.489 |
|
1986 |
Green L, Schlaffer I, Wright K, Moreno ML, Berand D, Hager G, Stein J, Stein G. Cell cycle-dependent expression of a stable episomal human histone gene in a mouse cell. Proceedings of the National Academy of Sciences of the United States of America. 83: 2315-9. PMID 3458197 DOI: 10.1073/Pnas.83.8.2315 |
0.42 |
|
1984 |
Miller PA, Ostrowski MC, Hager GL, Simons SS. Covalent and noncovalent receptor-glucocorticoid complexes preferentially bind to the same regions of the long terminal repeat of murine mammary tumor virus proviral DNA. Biochemistry. 23: 6883-9. PMID 6099146 DOI: 10.1021/Bi00321A093 |
0.399 |
|
1984 |
Hager GL, Richard-Foy H, Kessel M, Wheeler D, Lichtler AC, Ostrowski MC. The mouse mammary tumor virus model in studies of glucocorticoid regulation. Recent Progress in Hormone Research. 40: 121-42. PMID 6091192 DOI: 10.1016/B978-0-12-571140-1.50008-6 |
0.339 |
|
1984 |
Ostrowski M, Huang A, Kessel M, Wolford R, Hager G. Modulation of enhancer activity by the hormone responsive regulatory element from mouse mammary tumor virus. The Embo Journal. 3: 1891-1899. DOI: 10.1002/J.1460-2075.1984.Tb02064.X |
0.398 |
|
1983 |
Ostrowski MC, Richard-Foy H, Wolford RG, Berard DS, Hager GL. Glucocorticoid regulation of transcription at an amplified, episomal promoter. Molecular and Cellular Biology. 3: 2045-57. PMID 6318079 DOI: 10.1128/Mcb.3.11.2045 |
0.472 |
|
1982 |
Huang AL, Ostrowski MC, Berard D, Hager GL. Glucocorticoid regulation of the Ha-MuSV p21 gene conferred by sequences from mouse mammary tumor virus. Cell. 27: 245-55. PMID 6277498 DOI: 10.1016/0092-8674(81)90408-6 |
0.372 |
|
1981 |
Ostrowski MC, Berard D, Hager GL. Specific transcriptional initiation in vitro on murine type C retrovirus promoters. Proceedings of the National Academy of Sciences of the United States of America. 78: 4485-9. PMID 6270679 DOI: 10.1073/Pnas.78.7.4485 |
0.372 |
|
1977 |
Holland MJ, Hager GL, Rutter WJ. Transcription of yeast DNA by homologous RNA polymerases I and II: selective transcription of ribosomal genes by RNA polymerase I. Biochemistry. 16: 16-24. PMID 318852 DOI: 10.1021/Bi00620A003 |
0.342 |
|
1976 |
Hager G, Holland M, Valenzuela P, Weinberg F, Rutter WJ. RNA Polymerases and Transcriptive Specificity in Saccharomyces cerevisiae Cold Spring Harbor Monograph Archive. 6: 745-762. DOI: 10.1101/087969115.6.745 |
0.435 |
|
1974 |
Goldberg M, Perriard JC, Hager G, Hallick RB, Rutter WJ. Transcriptional systems in eukaryotic cells. Basic Life Sciences. 3: 241-56. PMID 4207225 DOI: 10.1007/978-1-4613-4529-9_19 |
0.316 |
|
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