Philippe Soriano, Ph.D - Publications

Affiliations: 
1987-1993 Molecular Genetics Baylor College of Medicine, Houston, TX 
 1993-2008 Basic Sciences Fred Hutchinson Cancer Research Center, Seattle, WA, United States 
 2008- Cell, Developmental, and Regenerative Biology Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Developmental Biology, Genetics, Signal Transduction
Website:
https://icahn.mssm.edu/profiles/philippe-m-soriano

159 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Ray AT, Mazot P, Brewer JR, Catela C, Dinsmore CJ, Soriano P. FGF signaling regulates development by processes beyond canonical pathways. Genes and Development. 34: 1735-1752. PMID 33184218 DOI: gad.342956.120  1
2020 Clark JF, Dinsmore CJ, Soriano P. A most formidable arsenal: genetic technologies for building a better mouse. Genes and Development. 34: 1256-1286. PMID 33004485 DOI: 10.1101/gad.342089.120  1
2020 Dinsmore CJ, Soriano P. A Fateful Decision: Tgif1 and Cardiac Neural Crest Identity. Developmental Cell. 53: 255-256. PMID 32369738 DOI: 10.1016/j.devcel.2020.04.013  1
2019 Soriano P. Commentary on Tam and Zhou, 1996. Developmental Biology. 447: 127-136. PMID 30905353 DOI: 10.1016/j.ydbio.2019.02.006  0.01
2019 Kurowski A, Molotkov A, Soriano P. FGFR1 regulates trophectoderm development and facilitates blastocyst implantation. Developmental Biology. 446: 94-101. PMID 30552867 DOI: 10.1016/j.ydbio.2018.12.008  1
2018 Molotkov A, Soriano P. Distinct mechanisms for PDGF and FGF signaling in primitive endoderm development. Developmental Biology. 442: 155-161. PMID 30026121 DOI: 10.1016/j.ydbio.2018.07.010  1
2018 Soriano P. Intersectional gene inactivation: there is more to conditional mutagenesis than Cre. Science China. Life Sciences. 61: 1115-1117. PMID 29785571 DOI: 10.1007/s11427-018-9291-2  0.01
2018 Dinsmore CJ, Soriano P. MAPK and PI3K signaling: At the crossroads of neural crest development. Developmental Biology. 444: S79-S97. PMID 29453943 DOI: 10.1016/j.ydbio.2018.02.003  1
2017 He F, Soriano P. Deregulated PDGFRα signaling alters coronal suture morphogenesis and leads to craniosynostosis through endochondral ossification. Development (Cambridge, England). PMID 28947535 DOI: 10.1242/dev.151068  1
2017 Fantauzzo KA, Soriano P. Generation of an immortalized mouse embryonic palatal mesenchyme cell line. Plos One. 12: e0179078. PMID 28582446 DOI: 10.1371/journal.pone.0179078  1
2017 Molotkov A, Mazot P, Brewer JR, Cinalli RM, Soriano P. Distinct Requirements for FGFR1 and FGFR2 in Primitive Endoderm Development and Exit from Pluripotency. Developmental Cell. PMID 28552557 DOI: 10.1016/j.devcel.2017.05.004  1
2016 Fantauzzo KA, Soriano P. PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα. Genes & Development. 30: 2443-2458. PMID 27856617 DOI: 10.1101/gad.288746.116  1
2016 Brewer JR, Mazot P, Soriano P. Genetic insights into the mechanisms of Fgf signaling. Genes & Development. 30: 751-71. PMID 27036966 DOI: 10.1101/gad.277137.115  1
2016 Vasudevan HN, Soriano P. A Thousand and One Receptor Tyrosine Kinases: Wherein the Specificity? Current Topics in Developmental Biology. 117: 393-404. PMID 26969991 DOI: 10.1016/bs.ctdb.2015.10.016  1
2015 Lewis AE, Hwa J, Wang R, Soriano P, Bush JO. Neural crest defects in ephrin-B2 mutant mice are non-autonomous and originate from defects in the vasculature. Developmental Biology. PMID 26385750 DOI: 10.1016/j.ydbio.2015.08.021  1
2015 Brewer JR, Molotkov A, Mazot P, Hoch RV, Soriano P. Fgfr1 regulates development through the combinatorial use of signaling proteins Genes & Development. 29: 1863-1874. PMID 26341559 DOI: 10.1101/gad.264994.115  1
2015 He F, Soriano P. Sox10ER(T2) CreER(T2) mice enable tracing of distinct neural crest cell populations. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 26250625 DOI: 10.1002/dvdy.24320  1
2015 Vasudevan HN, Mazot P, He F, Soriano P. Receptor tyrosine kinases modulate distinct transcriptional programs by differential usage of intracellular pathways. Elife. 4. PMID 25951516 DOI: 10.7554/eLife.07186  1
2015 Zou H, Feng R, Huang Y, Tripodi J, Najfeld V, Tsankova NM, Jahanshahi M, Olson LE, Soriano P, Friedel RH. Double minute amplification of mutant PDGF receptor α in a mouse glioma model. Scientific Reports. 5: 8468. PMID 25683249 DOI: 10.1038/srep08468  1
2015 Kocabayoglu P, Lade A, Lee YA, Dragomir AC, Sun X, Fiel MI, Thung S, Aloman C, Soriano P, Hoshida Y, Friedman SL. β-PDGF receptor expressed by hepatic stellate cells regulates fibrosis in murine liver injury, but not carcinogenesis. Journal of Hepatology. 63: 141-7. PMID 25678385 DOI: 10.1016/j.jhep.2015.01.036  0.04
2015 Fantauzzo KA, Soriano P. Receptor tyrosine kinase signaling: regulating neural crest development one phosphate at a time. Current Topics in Developmental Biology. 111: 135-82. PMID 25662260 DOI: 10.1016/bs.ctdb.2014.11.005  1
2015 Vasudevan HN, Mazot P, He F, Soriano P. Receptor tyrosine kinases modulate distinct transcriptional programs by differential usage of intracellular pathways Elife. 4. DOI: 10.7554/eLife.07186  1
2014 Vasudevan HN, Soriano P. SRF regulates craniofacial development through selective recruitment of MRTF cofactors by PDGF signaling. Developmental Cell. 31: 332-344. PMID 25453829 DOI: 10.1016/j.devcel.2014.10.005  1
2014 Fantauzzo KA, Soriano P. PI3K-mediated PDGFRα signaling regulates survival and proliferation in skeletal development through p53-dependent intracellular pathways. Genes & Development. 28: 1005-17. PMID 24788519 DOI: 10.1101/gad.238709.114  1
2013 He F, Soriano P. A critical role for PDGFRα signaling in medial nasal process development. Plos Genetics. 9: e1003851. PMID 24086166 DOI: 10.1371/journal.pgen.1003851  1
2013 Friedel RH, Friedel CC, Bonfert T, Shi R, Rad R, Soriano P. Clonal expansion analysis of transposon insertions by high-throughput sequencing identifies candidate cancer genes in a PiggyBac mutagenesis screen. Plos One. 8: e72338. PMID 23940809 DOI: 10.1371/journal.pone.0072338  1
2013 Lewis AE, Vasudevan HN, O'Neill AK, Soriano P, Bush JO. The widely used Wnt1-Cre transgene causes developmental phenotypes by ectopic activation of Wnt signaling. Developmental Biology. 379: 229-34. PMID 23648512 DOI: 10.1016/j.ydbio.2013.04.026  1
2012 Bush JO, Soriano P. Eph/ephrin signaling: genetic, phosphoproteomic, and transcriptomic approaches. Seminars in Cell & Developmental Biology. 23: 26-34. PMID 22040918 DOI: 10.1016/j.semcdb.2011.10.018  1
2011 Olson LE, Soriano P. PDGFRβ signaling regulates mural cell plasticity and inhibits fat development. Developmental Cell. 20: 815-26. PMID 21664579 DOI: 10.1016/j.devcel.2011.04.019  1
2011 Bush JO, Soriano P. A mechanistic basis for craniofacial anomalies associated with craniofrontonasal syndrome Developmental Biology. 356: 120-121. DOI: 10.1016/j.ydbio.2011.05.065  0.04
2010 Bush JO, Soriano P. Ephrin-B1 forward signaling regulates craniofacial morphogenesis by controlling cell proliferation across Eph-ephrin boundaries. Genes & Development. 24: 2068-80. PMID 20844017 DOI: 10.1101/gad.1963210  1
2010 Friedel RH, Soriano P. Gene trap mutagenesis in the mouse Methods in Enzymology. 477: 243-269. PMID 20699145 DOI: 10.1016/S0076-6879(10)77013-0  1
2010 Wassarman PM, Soriano PM. Technological advances in mouse development studies. Preface. Methods in Enzymology. 477: xix. PMID 20699132 DOI: 10.1016/S0076-6879(10)77030-0  1
2010 Wassarman PM, Soriano PM. Guide to techniques in mouse development. Preface. Methods in Enzymology. 476: xix. PMID 20691856 DOI: 10.1016/S0076-6879(10)76028-6  1
2010 Raymond CS, Soriano P. ROSA26Flpo deleter mice promote efficient inversion of conditional gene traps in vivo. Genesis (New York, N.Y. : 2000). 48: 603-6. PMID 20665730 DOI: 10.1002/dvg.20659  1
2009 Bush JO, Soriano P. Ephrin-B1 regulates axon guidance by reverse signaling through a PDZ-dependent mechanism. Genes & Development. 23: 1586-99. PMID 19515977 DOI: 10.1101/gad.1807209  1
2009 Olson LE, Soriano P. Increased PDGFRalpha activation disrupts connective tissue development and drives systemic fibrosis. Developmental Cell. 16: 303-13. PMID 19217431 DOI: 10.1016/j.devcel.2008.12.003  1
2009 Bush JO, Soriano P. Analysis of signaling downstream of ephrin-B1 during development Developmental Biology. 331: 479. DOI: 10.1016/j.ydbio.2009.05.347  0.12
2008 Schmahl J, Rizzolo K, Soriano P. The PDGF signaling pathway controls multiple steroid-producing lineages. Genes & Development. 22: 3255-67. PMID 19056881 DOI: 10.1101/gad.1723908  1
2008 Qiu R, Wang X, Davy A, Wu C, Murai K, Zhang H, Flanagan JG, Soriano P, Lu Q. Regulation of neural progenitor cell state by ephrin-B. The Journal of Cell Biology. 181: 973-83. PMID 18541704 DOI: 10.1083/jcb.200708091  1
2008 Bush JO, Soriano P. Ephrin-B signaling in mouse development Developmental Biology. 319: 474. DOI: 10.1016/j.ydbio.2008.05.034  0.08
2007 Raymond CS, Soriano P. High-efficiency FLP and PhiC31 site-specific recombination in mammalian cells. Plos One. 2: e162. PMID 17225864 DOI: 10.1371/journal.pone.0000162  1
2007 Davy A, Soriano P. Ephrin-B2 forward signaling regulates somite patterning and neural crest cell development. Developmental Biology. 304: 182-93. PMID 17223098 DOI: 10.1016/j.ydbio.2006.12.028  1
2007 Schmahl J, Raymond CS, Soriano P. PDGF signaling specificity is mediated through multiple immediate early genes. Nature Genetics. 39: 52-60. PMID 17143286 DOI: 10.1038/ng1922  1
2006 Soriano P. Genotyping Embryonic Stem (ES) Cell Colonies Prior to Picking. Csh Protocols. 2006. PMID 22485849 DOI: 10.1101/pdb.prot4415  0.01
2006 Davy A, Bush JO, Soriano P. Inhibition of gap junction communication at ectopic Eph/ephrin boundaries underlies craniofrontonasal syndrome. Plos Biology. 4: e315. PMID 16968134 DOI: 10.1371/journal.pbio.0040315  1
2006 Soriano P. Mouse development: from black eyes to knockouts. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 235: 2291. PMID 16894612 DOI: 10.1002/dvdy.20899  0.01
2006 Raymond CS, Soriano P. Engineering mutations: deconstructing the mouse gene by gene. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 235: 2424-36. PMID 16724325 DOI: 10.1002/dvdy.20845  1
2006 Hoch RV, Soriano P. Context-specific requirements for Fgfr1 signaling through Frs2 and Frs3 during mouse development. Development (Cambridge, England). 133: 663-73. PMID 16421190 DOI: 10.1242/dev.02242  1
2006 Nord AS, Chang PJ, Conklin BR, Cox AV, Harper CA, Hicks GG, Huang CC, Johns SJ, Kawamoto M, Liu S, Meng EC, Morris JH, Rossant J, Ruiz P, Skarnes WC, ... Soriano P, et al. The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse. Nucleic Acids Research. 34: D642-8. PMID 16381950 DOI: 10.1093/nar/gkj097  1
2006 Beutler L, Schmahl J, Soriano P. 470 A ROLE FOR PLATELET-DERIVED GROWTH FACTOR RECEPTOR ALPHA IN HEMATOPOIESIS. Journal of Investigative Medicine. 54: S160.3-S160. DOI: 10.2310/6650.2005.X0004.469  0.04
2005 Davy A, Soriano P. Ephrin signaling in vivo: look both ways. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 232: 1-10. PMID 15580616 DOI: 10.1002/dvdy.20200  1
2005 Xu X, Bringas P, Soriano P, Chai Y. PDGFR-alpha signaling is critical for tooth cusp and palate morphogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 232: 75-84. PMID 15543606 DOI: 10.1002/dvdy.20197  1
2004 Ding H, Wu X, Boström H, Kim I, Wong N, Tsoi B, O'Rourke M, Koh GY, Soriano P, Betsholtz C, Hart TC, Marazita ML, Field LL, Tam PP, Nagy A. A specific requirement for PDGF-C in palate formation and PDGFR-alpha signaling. Nature Genetics. 36: 1111-6. PMID 15361870 DOI: 10.1038/ng1415  1
2004 Austin CP, Battey JF, Bradley A, Bucan M, Capecchi M, Collins FS, Dove WF, Duyk G, Dymecki S, Eppig JT, Grieder FB, Heintz N, Hicks G, Insel TR, Joyner A, ... ... Soriano P, et al. The knockout mouse project. Nature Genetics. 36: 921-4. PMID 15340423 DOI: 10.1038/ng0904-921  1
2004 Aubin J, Davy A, Soriano P. In vivo convergence of BMP and MAPK signaling pathways: impact of differential Smad1 phosphorylation on development and homeostasis. Genes & Development. 18: 1482-94. PMID 15198985 DOI: 10.1101/gad.1202604  1
2004 Skarnes WC, von Melchner H, Wurst W, Hicks G, Nord AS, Cox T, Young SG, Ruiz P, Soriano P, Tessier-Lavigne M, Conklin BR, Stanford WL, Rossant J. A public gene trap resource for mouse functional genomics. Nature Genetics. 36: 543-4. PMID 15167922 DOI: 10.1038/ng0604-543  1
2004 Davy A, Aubin J, Soriano P. Ephrin-B1 forward and reverse signaling are required during mouse development. Genes & Development. 18: 572-83. PMID 15037550 DOI: 10.1101/gad.1171704  1
2004 Chen WV, Delrow J, Corrin PD, Frazier JP, Soriano P. Identification and validation of PDGF transcriptional targets by microarray-coupled gene-trap mutagenesis. Nature Genetics. 36: 304-12. PMID 14981515 DOI: 10.1038/ng1306  1
2003 Chen WV, Soriano P. Gene trap mutagenesis in embryonic stem cells. Methods in Enzymology. 365: 367-86. PMID 14696359  1
2003 Tallquist MD, French WJ, Soriano P. Additive effects of PDGF receptor β signaling pathways in vascular smooth muscle cell development Plos Biology. 1. PMID 14624252 DOI: 10.1371/journal.pbio.0000052  1
2003 Hoch RV, Soriano P. Roles of PDGF in animal development. Development (Cambridge, England). 130: 4769-84. PMID 12952899 DOI: 10.1242/dev.00721  1
2003 Awatramani R, Soriano P, Rodriguez C, Mai JJ, Dymecki SM. Cryptic boundaries in roof plate and choroid plexus identified by intersectional gene activation. Nature Genetics. 35: 70-5. PMID 12923530 DOI: 10.1038/ng1228  1
2003 Hamilton TG, Klinghoffer RA, Corrin PD, Soriano P. Evolutionary divergence of platelet-derived growth factor alpha receptor signaling mechanisms Molecular and Cellular Biology. 23: 4013-4025. PMID 12748302 DOI: 10.1128/MCB.23.11.4013-4025.2003  1
2003 Tallquist MD, Soriano P. Cell autonomous requirement for PDGFRα in populations of cranial and cardiac neural crest cells Development. 130: 507-518. PMID 12490557 DOI: 10.1242/dev.00241  1
2002 Hildebrand JD, Soriano P. Overlapping and unique roles for C-terminal binding protein 1 (CtBP1) and CtBP2 during mouse development. Molecular and Cellular Biology. 22: 5296-307. PMID 12101226  1
2002 Komada M, Soriano P. [Beta]IV-spectrin regulates sodium channel clustering through ankyrin-G at axon initial segments and nodes of Ranvier. The Journal of Cell Biology. 156: 337-48. PMID 11807096 DOI: 10.1083/jcb.200110003  1
2002 Goetinck PF, Papaionnou G, Rossant J, Tam P, Anderson K, Hastie N, Soriano P, Bullock S, Rodriguez T, Dunwoodie S, Wilson V, Thomas P, Conlon F, Pevney L. Remembering Rosa Beddington--a tribute from her friends and colleagues Developmental Dynamics : An Official Publication of the American Association of Anatomists. 223: 3-11. PMID 11803565 DOI: 10.1002/dvdy.10053  1
2002 Klinghoffer RA, Hamilton TG, Hoch R, Soriano P. An allelic series at the PDGFαR locus indicates unequal contributions of distinct signaling pathways during development Developmental Cell. 2: 103-113. PMID 11782318 DOI: 10.1016/S1534-5807(01)00103-4  1
2001 Awatramani R, Soriano P, Mai JJ, Dymecki S. An Flp indicator mouse expressing alkaline phosphatase from the ROSA26 locus. Nature Genetics. 29: 257-9. PMID 11687793 DOI: 10.1038/ng1101-257  1
2001 Medico E, Gambarotta G, Gentile A, Comoglio PM, Soriano P. A gene trap vector system for identifying transcriptionally responsive genes. Nature Biotechnology. 19: 579-82. PMID 11385465 DOI: 10.1038/89343  0.04
2001 Klinghoffer RA, Mueting-Nelsen PF, Faerman A, Shani M, Soriano P. The two PDGF receptors maintain conserved signaling in vivo despite divergent embryological functions Molecular Cell. 7: 343-354. PMID 11239463 DOI: 10.1016/S1097-2765(01)00182-4  1
2001 Nadeau JH, Balling R, Barsh G, Beier D, Brown SD, Bucan M, Camper S, Carlson G, Copeland N, Eppig J, Fletcher C, Frankel WN, Ganten D, Goldowitz D, Goodnow C, ... ... Soriano P, et al. Sequence interpretation. Functional annotation of mouse genome sequences. Science (New York, N.Y.). 291: 1251-5. PMID 11233449 DOI: 10.1126/science.1058244  1
2001 Medico E, Gentile A, Soriano P, Comoglio P. A genome-wide trap screening procedure for transcriptionally responsive genes Nature Genetics. 27: 73-73. DOI: 10.1038/87208  0.08
2000 Tallquist MD, Klinghoffer RA, Heuchel R, Mueting-Nelsen PF, Corrin PD, Heldin CH, Johnson RJ, Soriano P. Retention of PDGFR-β function in mice in the absence of phosphatidylinositol 3′-kinase anti phospholipase Cγ signaling pathways Genes and Development. 14: 3179-3190. PMID 11124809 DOI: 10.1101/gad.844700  1
2000 Farley FW, Soriano P, Steffen LS, Dymecki SM. Widespread recombinase expression using FLPeR (flipper) mice. Genesis (New York, N.Y. : 2000). 28: 106-10. PMID 11105051 DOI: 10.1002/1526-968X(200011/12)28:3/4<106::AID-GENE30>3.0.CO;2-T  0.01
2000 Tallquist MD, Weismann KE, Hellstrom M, Soriano P. Early myotome specification regulates PDGFA expression and axial skeleton development Development. 127: 5059-5070. PMID 11060232  1
2000 Komada M, McLean DJ, Griswold MD, Russell LD, Soriano P. E-MAP-115, encoding a microtubule-associated protein, is a retinoic acid-inducible gene required for spermatogenesis. Genes & Development. 14: 1332-42. PMID 10837026  1
2000 Li X, Pontén A, Aase K, Karlsson L, Abramsson A, Uutela M, Bäckström G, Hellström M, Boström H, Li H, Soriano P, Betsholtz C, Heldin CH, Alitalo K, Ostman A, et al. PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor. Nature Cell Biology. 2: 302-9. PMID 10806482 DOI: 10.1038/35010579  1
2000 Klesert TR, Cho DH, Clark JI, Maylie J, Adelman J, Snider L, Yuen EC, Soriano P, Tapscott SJ. Mice deficient in Six5 develop cataracts: Implications for myotonic dystrophy Nature Genetics. 25: 105-109. PMID 10802667 DOI: 10.1038/75490  1
2000 Chai Y, Jiang X, Ito Y, Bringas P, Han J, Rowitch DH, Soriano P, McMahon AP, Sucov HM. Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis. Development (Cambridge, England). 127: 1671-9. PMID 10725243  1
2000 Jiang X, Rowitch DH, Soriano P, McMahon AP, Sucov HM. Fate of the mammalian cardiac neural crest. Development (Cambridge, England). 127: 1607-16. PMID 10725237  1
2000 Tallquist MD, Soriano P. Epiblast-restricted Cre expression in MORE mice: A tool to distinguish embryonic vs. extra-embryonic gene function Genesis. 26: 113-115. PMID 10686601 DOI: 10.1002/(SICI)1526-968X(200002)26:2<113::AID-GENE3>3.0.CO;2-2  1
1999 Tallquist MD, Soriano P, Klinghoffer RA. Growth factor signaling pathways in vascular development Oncogene. 18: 7917-7932. PMID 10630644  1
1999 Davy A, Gale NW, Murray EW, Klinghoffer RA, Soriano P, Feuerstein C, Robbins SM. Compartmentalized signaling by GPI-anchored ephrin-A5 requires the Fyn tyrosine kinase to regulate cellular adhesion. Genes & Development. 13: 3125-35. PMID 10601038 DOI: 10.1101/gad.13.23.3125  1
1999 Hildebrand JD, Soriano P. Shroom, a PDZ domain-containing actin-binding protein, is required for neural tube morphogenesis in mice. Cell. 99: 485-97. PMID 10589677 DOI: 10.1016/S0092-8674(00)81537-8  0.76
1999 Andrews A, Balciunaite E, Leong FL, Tallquist M, Soriano P, Refojo M, Kazlauskas A. Platelet-derived growth factor plays a key role in proliferative vitreoretinopathy. Investigative Ophthalmology & Visual Science. 40: 2683-9. PMID 10509666  1
1999 Heuchel R, Berg A, Tallquist M, Ahlén K, Reed RK, Rubin K, Claesson-Welsh L, Heldin CH, Soriano P. Platelet-derived growth factor beta receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3' kinase signaling. Proceedings of the National Academy of Sciences of the United States of America. 96: 11410-5. PMID 10500190 DOI: 10.1073/pnas.96.20.11410  1
1999 Ohlsson R, Falck P, Hellström M, Lindahl P, Boström H, Franklin G, Ahrlund-Richter L, Pollard J, Soriano P, Betsholtz C. PDGFB regulates the development of the labyrinthine layer of the mouse fetal placenta. Developmental Biology. 212: 124-36. PMID 10419690 DOI: 10.1006/dbio.1999.9306  1
1999 Komada M, Soriano P. Hrs, a FYVE finger protein localized to early endosomes, is implicated in vesicular traffic and required for ventral folding morphogenesis. Genes & Development. 13: 1475-85. PMID 10364163 DOI: 10.1101/gad.13.11.1475  1
1999 Klinghoffer RA, Sachsenmaier C, Cooper JA, Soriano P. Src family kinases are required for integrin but not PDGFR signal transduction. The Embo Journal. 18: 2459-71. PMID 10228160 DOI: 10.1093/emboj/18.9.2459  1
1999 Wilde A, Beattie EC, Lem L, Riethof DA, Liu SH, Mobley WC, Soriano P, Brodsky FM. EGF receptor signaling stimulates SRC kinase phosphorylation of clathrin, influencing clathrin redistribution and EGF uptake. Cell. 96: 677-87. PMID 10089883  1
1999 Lanier LM, Gates MA, Witke W, Menzies AS, Wehman AM, Macklis JD, Kwiatkowski D, Soriano P, Gertler FB. Mena is required for neurulation and commissure formation. Neuron. 22: 313-25. PMID 10069337 DOI: 10.1016/S0896-6273(00)81092-2  1
1999 Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nature Genetics. 21: 70-1. PMID 9916792 DOI: 10.1038/5007  0.01
1998 Gallagher E, Howell BW, Soriano P, Cooper JA, Hawkes R. Cerebellar abnormalities in the disabled (mdab1-1) mouse Journal of Comparative Neurology. 402: 238-251. PMID 9845246 DOI: 10.1002/(SICI)1096-9861(19981214)402:2<238::AID-CNE8>3.0.CO;2-H  1
1998 Lindahl P, Hellström M, Kalén M, Karlsson L, Pekny M, Pekna M, Soriano P, Betsholtz C. Paracrine PDGF-B/PDGF-Rbeta signaling controls mesangial cell development in kidney glomeruli. Development (Cambridge, England). 125: 3313-22. PMID 9693135  1
1998 Fransen E, D'Hooge R, Van Camp G, Verhoye M, Sijbers J, Reyniers E, Soriano P, Kamiguchi H, Willemsen R, Koekkoek SK, De Zeeuw CI, De Deyn PP, Van der Linden A, Lemmon V, Kooy RF, et al. L1 knockout mice show dilated ventricles, vermis hypoplasia and impaired exploration patterns. Human Molecular Genetics. 7: 999-1009. PMID 9580664 DOI: 10.1093/hmg/7.6.999  1
1998 Crosby JR, Seifert RA, Soriano P, Bowen-Pope DF. Chimaeric analysis reveals role of Pdgf receptors in all muscle lineages. Nature Genetics. 18: 385-8. PMID 9537425 DOI: 10.1038/ng0498-385  1
1998 Foley KP, McArthur GA, Quéva C, Hurlin PJ, Soriano P, Eisenman RN. Targeted disruption of the MYC antagonist MAD1 inhibits cell cycle exit during granulocyte differentiation. The Embo Journal. 17: 774-85. PMID 9451002 DOI: 10.1093/emboj/17.3.774  1
1998 Friedrich GA, Hildebrand JD, Soriano P. The secretory protein Sec8 is required for paraxial mesoderm formation in the mouse. Developmental Biology. 192: 364-74. PMID 9441674 DOI: 10.1006/dbio.1997.8727  0.76
1998 Cohen NR, Taylor JS, Scott LB, Guillery RW, Soriano P, Furley AJ. Errors in corticospinal axon guidance in mice lacking the neural cell adhesion molecule L1. Current Biology : Cb. 8: 26-33. PMID 9427628  1
1997 Howell BW, Hawkes R, Soriano P, Cooper JA. Neuronal position in the developing brain is regulated by mouse disabled-1 Nature. 389: 733-737. PMID 9338785 DOI: 10.1038/39607  1
1997 Chan VWF, Meng F, Soriano P, DeFranco AL, Lowell CA. Characterization of the B lymphocyte populations in lyn-deficient mice and the role of lyn in signal initiation and down-regulation Immunity. 7: 69-81. PMID 9252121 DOI: 10.1016/S1074-7613(00)80511-7  1
1997 Soriano P. The PDGF alpha receptor is required for neural crest cell development and for normal patterning of the somites. Development (Cambridge, England). 124: 2691-700. PMID 9226440  0.01
1997 Zambrowicz BP, Imamoto A, Fiering S, Herzenberg LA, Kerr WG, Soriano P. Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells. Proceedings of the National Academy of Sciences of the United States of America. 94: 3789-94. PMID 9108056 DOI: 10.1073/pnas.94.8.3789  1
1996 Gertler FB, Niebuhr K, Reinhard M, Wehland J, Soriano P. Mena, a relative of VASP and Drosophila Enabled, is implicated in the control of microfilament dynamics. Cell. 87: 227-39. PMID 8861907 DOI: 10.1016/S0092-8674(00)81341-0  1
1996 Lowell CA, Soriano P. Knockouts of Src-family kinases: stiff bones, wimpy T cells, and bad memories. Genes & Development. 10: 1845-57. PMID 8756343 DOI: 10.1101/gad.10.15.1845  0.01
1996 Lowell CA, Niwa M, Soriano P, Varmus HE. Deficiency of the Hck and Src tyrosine kinases results in extreme levels of extramedullary hematopoiesis. Blood. 87: 1780-92. PMID 8634424  1
1995 MacGregor GR, Zambrowicz BP, Soriano P. Tissue non-specific alkaline phosphatase is expressed in both embryonic and extraembryonic lineages during mouse embryogenesis but is not required for migration of primordial germ cells. Development (Cambridge, England). 121: 1487-96. PMID 7789278  1
1995 Thomas SM, Soriano P, Imamoto A. Specific and redundant roles of Src and Fyn in organizing the cytoskeleton Nature. 376: 267-271. PMID 7617039 DOI: 10.1038/376267a0  1
1995 Soriano P. Gene targeting in ES cells. Annual Review of Neuroscience. 18: 1-18. PMID 7605056 DOI: 10.1146/annurev.ne.18.030195.000245  0.01
1994 Imamoto A, Soriano P, Stein PL. Genetics of signal transduction: tales from the mouse. Current Opinion in Genetics & Development. 4: 40-6. PMID 8193538 DOI: 10.1016/0959-437x(94)90089-2  1
1994 Lowell CA, Soriano P, Varmus HE. Functional overlap in the src gene family: inactivation of hck and fgr impairs natural immunity. Genes & Development. 8: 387-98. PMID 8125254  1
1994 Zhuang Y, Soriano P, Weintraub H. The helix-loop-helix gene E2A is required for B cell formation. Cell. 79: 875-84. PMID 8001124 DOI: 10.1016/0092-8674(94)90076-0  1
1994 Beggs HE, Soriano P, Maness PF. NCAM-dependent neurite outgrowth is inhibited in neurons from Fyn-minus mice. The Journal of Cell Biology. 127: 825-33. PMID 7962063 DOI: 10.1083/jcb.127.3.825  1
1994 Chen Z, Friedrich GA, Soriano P. Transcriptional enhancer factor 1 disruption by a retroviral gene trap leads to heart defects and embryonic lethality in mice. Genes & Development. 8: 2293-301. PMID 7958896 DOI: 10.1101/gad.8.19.2293  0.6
1994 Stein PL, Vogel H, Soriano P. Combined deficiencies of Src, Fyn, and Yes tyrosine kinases in mutant mice. Genes & Development. 8: 1999-2007. PMID 7958873 DOI: 10.1101/gad.8.17.1999  1
1994 Soriano P. Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice. Genes & Development. 8: 1888-96. PMID 7958864 DOI: 10.1101/gad.8.16.1888  0.01
1994 Kiefer F, Anhauser I, Soriano P, Aguzzi A, Courtneidge SA, Wagner EF. Endothelial cell transformation by polyomavirus middle T antigen in mice lacking Src-related kinases Current Biology. 4: 100-109. PMID 7953508 DOI: 10.1016/S0960-9822(94)00025-4  1
1994 Ignelzi MA, Miller DR, Soriano P, Maness PF. Impaired neurite outgrowth of src-minus cerebellar neurons on the cell adhesion molecule L1. Neuron. 12: 873-84. PMID 7512817 DOI: 10.1016/0896-6273(94)90339-5  1
1994 Guy CT, Muthuswamy SK, Cardiff RD, Soriano P, Muller WJ. Activation of the c-Src tyrosine kinase is required for the induction of mammary tumors in transgenic mice. Genes & Development. 8: 23-32. PMID 7507074 DOI: 10.1101/gad.8.1.23  0.01
1993 Grompe M, al-Dhalimy M, Finegold M, Ou CN, Burlingame T, Kennaway NG, Soriano P. Loss of fumarylacetoacetate hydrolase is responsible for the neonatal hepatic dysfunction phenotype of lethal albino mice. Genes & Development. 7: 2298-307. PMID 8253378 DOI: 10.1101/gad.7.12a.2298  0.01
1993 Friedrich G, Soriano P. Insertional mutagenesis by retroviruses and promoter traps in embryonic stem cells. Methods in Enzymology. 225: 681-701. PMID 8231879 DOI: 10.1016/0076-6879(93)25044-3  1
1993 Boyce BF, Chen H, Soriano P, Mundy GR. Histomorphometric and immunocytochemical studies of src-related osteopetrosis. Bone. 14: 335-40. PMID 7689855 DOI: 10.1016/8756-3282(93)90161-3  1
1993 Thomas JE, Aguzzi A, Soriano P, Wagner EF, Brugge JS. Induction of tumor formation and cell transformation by polyoma middle T antigen in the absence of Src Oncogene. 8: 2521-2529. PMID 7689725  1
1993 Imamoto A, Soriano P. Disruption of the csk gene, encoding a negative regulator of Src family tyrosine kinases, leads to neural tube defects and embryonic lethality in mice. Cell. 73: 1117-24. PMID 7685657 DOI: 10.1016/0092-8674(93)90641-3  1
1993 Lowe C, Yoneda T, Boyce BF, Chen H, Mundy GR, Soriano P. Osteopetrosis in Src-deficient mice is due to an autonomous defect of osteoclasts. Proceedings of the National Academy of Sciences of the United States of America. 90: 4485-9. PMID 7685105 DOI: 10.1073/pnas.90.10.4485  1
1992 Stein PL, Lee HM, Rich S, Soriano P. pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells. Cell. 70: 741-50. PMID 1387588 DOI: 10.1016/0092-8674(92)90308-y  1
1992 Giese KP, Martini R, Lemke G, Soriano P, Schachner M. Mouse P0 gene disruption leads to hypomyelination, abnormal expression of recognition molecules, and degeneration of myelin and axons. Cell. 71: 565-76. PMID 1384988 DOI: 10.1016/0092-8674(92)90591-y  0.01
1992 Boyce BF, Yoneda T, Lowe C, Soriano P, Mundy GR. Requirement of pp60c-src expression for osteoclasts to form ruffled borders and resorb bone in mice. The Journal of Clinical Investigation. 90: 1622-7. PMID 1383278 DOI: 10.1172/JCI116032  0.04
1992 Grant SG, O'Dell TJ, Karl KA, Stein PL, Soriano P, Kandel ER. Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice. Science (New York, N.Y.). 258: 1903-10. PMID 1361685  1
1992 O'Dell TJ, Grant SG, Karl K, Soriano PM, Kandel ER. Pharmacological and genetic approaches to the analysis of tyrosine kinase function in long-term potentiation. Cold Spring Harbor Symposia On Quantitative Biology. 57: 517-26. PMID 1339688  1
1992 Boyce B, Chen H, Bouton A, Soriano P, Arnett T, Yoneda T, Mundy G. The major pefect in SRC-deficiency osteopetrosis lies in the osteoclast Bone. 13: A4-A4. DOI: 10.1016/8756-3282(92)90473-A  0.01
1991 Soriano P, Friedrich G, Lawinger P. Promoter interactions in retrovirus vectors introduced into fibroblasts and embryonic stem cells. Journal of Virology. 65: 2314-9. PMID 2016762 DOI: 10.1128/JVI.65.5.2314-2319.1991  1
1991 Soriano P, Montgomery C, Geske R, Bradley A. Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice Cell. 64: 693-702. PMID 1997203 DOI: 10.1016/0092-8674(91)90499-O  1
1991 Thomas JE, Soriano P, Brugge JS. Phosphorylation of c-Src on tyrosine 527 by another protein tyrosine kinase Science. 254: 568-571. PMID 1719633  1
1991 Friedrich G, Soriano P. Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes & Development. 5: 1513-23. PMID 1653172 DOI: 10.1101/gad.5.9.1513  1
1990 Gridley T, Gray DA, Orr-Weaver T, Soriano P, Barton DE, Francke U, Jaenisch R. Molecular analysis of the Mov 34 mutation: transcript disrupted by proviral integration in mice is conserved in Drosophila. Development (Cambridge, England). 109: 235-42. PMID 2209467  1
1990 Harbers K, Francke U, Soriano P, Jaenisch R, Müller U. Structure and chromosomal mapping of a highly polymorphic repetitive DNA sequence from the pseudoautosomal region of the mouse sex chromosomes. Cytogenetics and Cell Genetics. 53: 129-33. PMID 1973377 DOI: 10.1159/000132912  1
1987 Soriano P, Keitges EA, Schorderet DF, Harbers K, Gartler SM, Jaenisch R. High rate of recombination and double crossovers in the mouse pseudoautosomal region during male meiosis. Proceedings of the National Academy of Sciences of the United States of America. 84: 7218-20. PMID 3478692 DOI: 10.1073/pnas.84.20.7218  1
1987 Soriano P, Gridley T, Jaenisch R. Retroviruses and insertional mutagenesis in mice: proviral integration at the Mov 34 locus leads to early embryonic death. Genes & Development. 1: 366-75. PMID 2824282 DOI: 10.1101/gad.1.4.366  1
1987 Gridley T, Soriano P, Jaenisch R. Insertional mutagenesis in mice Trends in Genetics. 3: 162-166. DOI: 10.1016/0168-9525(87)90218-6  0.24
1986 Jaenisch R, Soriano P. Retroviruses as tools for mammalian development. Symposium On Fundamental Cancer Research. 39: 59-65. PMID 3321310  1
1986 Harbers K, Soriano P, Müller U, Jaenisch R. High frequency of unequal recombination in pseudoautosomal region shown by proviral insertion in transgenic mouse. Nature. 324: 682-5. PMID 3025741 DOI: 10.1038/324682a0  1
1986 Soriano P, Cone RD, Mulligan RC, Jaenisch R. Tissue-specific and ectopic expression of genes introduced into transgenic mice by retroviruses. Science (New York, N.Y.). 234: 1409-13. PMID 3024318  1
1986 Soriano P, Jaenisch R. Retroviruses as probes for mammalian development: allocation of cells to the somatic and germ cell lineages. Cell. 46: 19-29. PMID 3013418 DOI: 10.1016/0092-8674(86)90856-1  1
1984 Nicolau C, Legrand A, Soriano P. Liposomes for gene transfer and expression in vivo. Ciba Foundation Symposium. 103: 254-67. PMID 6200275 DOI: 10.1002/9780470720844.ch16  1
1983 Soriano P, Dijkstra J, Legrand A, Spanjer H, Londos-Gagliardi D, Roerdink F, Scherphof G, Nicolau C. Targeted and nontargeted liposomes for in vivo transfer to rat liver cells of a plasmid containing the preproinsulin I gene. Proceedings of the National Academy of Sciences of the United States of America. 80: 7128-31. PMID 6580630 DOI: 10.1073/pnas.80.23.7128  1
1983 Soriano P, Meunier-Rotival M, Bernardi G. The distribution of interspersed repeats is nonuniform and conserved in the mouse and human genomes. Proceedings of the National Academy of Sciences of the United States of America. 80: 1816-20. PMID 6572942 DOI: 10.1073/pnas.80.7.1816  1
1983 Nicolau C, Le Pape A, Soriano P, Fargette F, Juhel MF. In vivo expression of rat insulin after intravenous administration of the liposome-entrapped gene for rat insulin I. Proceedings of the National Academy of Sciences of the United States of America. 80: 1068-72. PMID 6341988 DOI: 10.1073/pnas.80.4.1068  1
1982 Soriano P, Szabo P, Bernardi G. The scattered distribution of actin genes in the mouse and human genomes. The Embo Journal. 1: 579-83. PMID 6329692  1
1982 Quax WJ, Dodemont HJ, Lenstra JA, Ramaekers FC, Soriano P, van Workum ME, Bernardi G, Bloemendal H. Genes coding for vimentin and actin in mammals and birds Advances in Experimental Medicine and Biology. 158: 349-357. PMID 6297276  1
1982 Meunier-Rotival M, Soriano P, Cuny G, Strauss F, Bernardi G. Sequence organization and genomic distribution of the major family of interspersed repeats of mouse DNA. Proceedings of the National Academy of Sciences of the United States of America. 79: 355-9. PMID 6281768 DOI: 10.1073/pnas.79.2.355  1
1982 Dodemont HJ, Soriano P, Quax WJ, Ramaekers F, Lenstra JA, Groenen MA, Bernardi G, Bloemendal H. The genes coding for the cytoskeletal proteins actin and vimentin in warm-blooded vertebrates Embo Journal. 1: 167-171. PMID 6201356  1
1982 Nicolau C, Le Pape A, Soriano P, Fargette F, Muh JP, Juhel MF. In vivo transfer and expression of the liposome encapsulated rat insulin gene. Progress in Clinical and Biological Research. 102: 321-30. PMID 6188166  1
1981 Cuny G, Soriano P, Macaya G, Bernardi G. The major components of the mouse and human genomes. 1. Preparation, basic properties and compositional heterogeneity. European Journal of Biochemistry / Febs. 115: 227-33. PMID 7238506  1
1981 Hampe A, Therwath A, Soriano P, Galibert F. Nucleotide sequence analysis of a cloned duck beta-globin cDNA. Gene. 14: 11-21. PMID 6894908 DOI: 10.1016/0378-1119(81)90144-x  0.01
1981 Soriano P, Macaya G, Bernardi G. The major components of the mouse and human genomes. 2. Reassociation kinetics. European Journal of Biochemistry / Febs. 115: 235-9. PMID 6263622  1
1978 Cuny G, Macaya G, Meunier-Rotival M, Soriano P, Bernardi G. Some properties of the major components of the mouse genome [proceedings]. Annales De Microbiologie. 129: 519-20. PMID 289305  1
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