Michael Weinfeld - Publications

Affiliations: 
Experimental Oncology University of Alberta, Edmonton, Alberta, Canada 
Area:
Molecular Biology, Oncology

115 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Rashed FB, Kate WD, Fanta M, Wiebe LI, Kumar P, Weinfeld M. Influence of 2-Nitroimidazoles in the Response of FaDu Cells to Ionizing Radiation and Hypoxia/Reoxygenation Stress. Antioxidants (Basel, Switzerland). 12. PMID 36829948 DOI: 10.3390/antiox12020389  0.41
2022 Jackson N, Alhussan A, Bromma K, Jay D, Donnelly JC, West FG, Lavasanifar A, Weinfeld M, Beckham W, Chithrani DB. Repurposing Antimalarial Pyronaridine as a DNA Repair Inhibitor to Exploit the Full Potential of Gold-Nanoparticle-Mediated Radiation Response. Pharmaceutics. 14. PMID 36559288 DOI: 10.3390/pharmaceutics14122795  0.435
2022 Turchi JJ, Pawelczak KS, Weinfeld M, McHugh PJ. Editorial: Targeting DNA repair and the DNA damage response: Beyond the standard PI3 kinase-like kinases. Frontiers in Oncology. 12: 1023500. PMID 36237323 DOI: 10.3389/fonc.2022.1023500  0.455
2022 Rashed FB, Diaz-Dussan D, Mashayekhi F, Macdonald D, Nation PN, Yang XH, Sokhi S, Stoica AC, El-Saidi H, Ricardo C, Narain R, Ismail IH, Wiebe LI, Kumar P, Weinfeld M. Cellular mechanism of action of 2-nitroimidazoles as hypoxia-selective therapeutic agents. Redox Biology. 52: 102300. PMID 35430547 DOI: 10.1016/j.redox.2022.102300  0.349
2022 Rychlowska M, Agyapong A, Weinfeld M, Schang LM. Zika Virus Induces Mitotic Catastrophe in Human Neural Progenitors by Triggering Unscheduled Mitotic Entry in the Presence of DNA Damage While Functionally Depleting Nuclear PNKP. Journal of Virology. e0033322. PMID 35412344 DOI: 10.1128/jvi.00333-22  0.437
2022 Weilbeer C, Jay D, Donnelly JC, Gentile F, Karimi-Busheri F, Yang X, Mani RS, Yu Y, Elmenoufy AH, Barakat KH, Tuszynski JA, Weinfeld M, West FG. Modulation of ERCC1-XPF Heterodimerization Inhibition Structural Modification of Small Molecule Inhibitor Side-Chains. Frontiers in Oncology. 12: 819172. PMID 35372043 DOI: 10.3389/fonc.2022.819172  0.474
2022 Jiang B, Murray C, Cole BL, Glover JNM, Chan GK, Deschenes J, Mani RS, Subedi S, Nerva JD, Wang AC, Lockwood CM, Mefford HC, Leary SES, Ojemann JG, Weinfeld M, et al. Mutations of the DNA repair gene PNKP in a patient with microcephaly, seizures, and developmental delay (MCSZ) presenting with a high-grade brain tumor. Scientific Reports. 12: 5386. PMID 35354845 DOI: 10.1038/s41598-022-09097-w  0.429
2021 Shin W, Alpaugh W, Hallihan LJ, Sinha S, Crowther E, Martin GR, Scheidl-Yee T, Yang X, Yoon G, Goldsmith T, Berger ND, de Almeida LG, Dufour A, Dobrinski I, Weinfeld M, et al. PNKP is required for maintaining the integrity of progenitor cell populations in adult mice. Life Science Alliance. 4. PMID 34226276 DOI: 10.26508/lsa.202000790  0.384
2021 Ciniero G, Elmenoufy AH, Gentile F, Weinfeld M, Deriu MA, West FG, Tuszynski JA, Dumontet C, Cros-Perrial E, Jordheim LP. Enhancing the activity of platinum-based drugs by improved inhibitors of ERCC1-XPF-mediated DNA repair. Cancer Chemotherapy and Pharmacology. PMID 33399940 DOI: 10.1007/s00280-020-04213-x  0.481
2020 Elmenoufy AH, Gentile F, Jay D, Karimi-Busheri F, Yang X, Soueidan OM, Mani RS, Ciniero G, Tuszynski JA, Weinfeld M, West FG. Design, synthesis and in vitro cell-free/cell-based biological evaluations of novel ERCC1-XPF inhibitors targeting DNA repair pathway. European Journal of Medicinal Chemistry. 204: 112658. PMID 32738410 DOI: 10.1016/J.Ejmech.2020.112658  0.517
2019 Gentile F, Elmenoufy AH, Ciniero G, Jay D, Karimi-Busheri F, Barakat KH, Weinfeld M, West FG, Tuszynski JA. Computer-Aided Drug Design of Small Molecule Inhibitors of the ERCC1-XPF Protein-Protein Interaction. Chemical Biology & Drug Design. PMID 31891209 DOI: 10.1111/Cbdd.13660  0.563
2019 Elmenoufy A, Gentile F, Jay D, Karimi-Busheri F, Yang X, Soueidan OM, Weilbeer C, Mani RS, Barakat KH, Tuszynski J, Weinfeld M, West FG. Targeting DNA Repair in Tumor Cells via Inhibition of ERCC1-XPF. Journal of Medicinal Chemistry. PMID 31369707 DOI: 10.1021/Acs.Jmedchem.9B00326  0.524
2019 Chen H, Crosley P, Azad AK, Gupta N, Gokul N, Xu Z, Weinfeld M, Postovit LM, Pangas SA, Hitt MM, Fu Y. RUNX3 Promotes the Tumorigenic Phenotype in KGN, a Human Granulosa Cell Tumor-Derived Cell Line. International Journal of Molecular Sciences. 20. PMID 31311113 DOI: 10.3390/Ijms20143471  0.335
2019 Elsaidi HR, Yang XH, Ahmadi F, Weinfeld M, Wiebe LI, Kumar P. Putative electron-affinic radiosensitizers and markers of hypoxic tissue: Synthesis and preliminary in vitro biological characterization of C3-amino-substituted benzotriazine dioxides (BTDOs). European Journal of Medicinal Chemistry. 165: 216-224. PMID 30684798 DOI: 10.1016/J.Ejmech.2019.01.009  0.301
2018 Mani RS, Mermershtain I, Abdou I, Fanta M, Hendzel MJ, Glover JNM, Weinfeld M. Domain analysis of PNKP/XRCC1 interactions: influence of genetic variants of XRCC1. The Journal of Biological Chemistry. PMID 30446622 DOI: 10.1074/Jbc.Ra118.004262  0.503
2018 Chalasani SL, Kawale AS, Akopiants K, Yu Y, Fanta M, Weinfeld M, Povirk LF. Persistent 3'-phosphate termini and increased cytotoxicity of radiomimetic DNA double-strand breaks in cells lacking polynucleotide kinase/phosphatase despite presence of an alternative 3'-phosphatase. Dna Repair. 68: 12-24. PMID 29807321 DOI: 10.1016/J.Dnarep.2018.05.002  0.521
2018 Shire Z, Vakili MR, Morgan TDR, Hall DG, Lavasanifar A, Weinfeld M. Nano-encapsulation of novel inhibitors of PNKP for selective sensitization to ionizing radiation and irinotecan and induction of synthetic lethality. Molecular Pharmaceutics. PMID 29688721 DOI: 10.1021/Acs.Molpharmaceut.8B00169  0.541
2017 Breslin C, Mani RS, Fanta M, Hoch N, Weinfeld M, Caldecott KW. The RIR motif in the scaffold protein XRCC1 mediates a low-affinity interaction with polynucleotide kinase/phosphatase (PNKP) during DNA single-strand break repair. The Journal of Biological Chemistry. PMID 28821613 DOI: 10.1074/Jbc.M117.806638  0.478
2017 Aceytuno RD, Piett CG, Havali-Shahriari Z, Edwards RA, Rey M, Ye R, Javed F, Fang S, Mani R, Weinfeld M, Hammel M, Tainer JA, Schriemer DC, Lees-Miller SP, Glover JNM. Structural and functional characterization of the PNKP-XRCC4-LigIV DNA repair complex. Nucleic Acids Research. PMID 28453785 DOI: 10.1093/Nar/Gkx275  0.524
2017 Havali-Shahriari Z, Weinfeld M, Glover JN. Characterization of DNA substrate binding to the phosphatase domain of the DNA repair enzyme, PNKP. Biochemistry. PMID 28276686 DOI: 10.1021/Acs.Biochem.6B01236  0.515
2017 Yang N, Weinfeld M, Lemieux H, Montpetit B, Goping IS. Photo-activation of the delocalized lipophilic cation D112 potentiates cancer selective ROS production and apoptosis. Cell Death & Disease. 8: e2587. PMID 28151485 DOI: 10.1038/Cddis.2017.19  0.378
2017 Zhao B, Zhang D, Li C, Yuan Z, Yu F, Zhong S, Jiang G, Yang YG, Le XC, Weinfeld M, Zhu P, Wang H. ATPase activity tightly regulates RecA nucleofilaments to promote homologous recombination. Cell Discovery. 3: 16053. PMID 28101376 DOI: 10.1038/Celldisc.2016.53  0.391
2016 Dutta A, Eckelmann B, Adhikari S, Ahmed KM, Sengupta S, Pandey A, Hegde PM, Tsai MS, Tainer JA, Weinfeld M, Hegde ML, Mitra S. Microhomology-mediated end joining is activated in irradiated human cells due to phosphorylation-dependent formation of the XRCC1 repair complex. Nucleic Acids Research. PMID 27994036 DOI: 10.1093/Nar/Gkw1262  0.503
2016 Karimi-Busheri F, Rasouli-Nia A, Weinfeld M. Key Issues Related to Cryopreservation and Storage of Stem Cells and Cancer Stem Cells: Protecting Biological Integrity. Advances in Experimental Medicine and Biology. 951: 1-12. PMID 27837550 DOI: 10.1007/978-3-319-45457-3_1  0.321
2016 Limudomporn P, Moonsom S, Leartsakulpanich U, Suntornthiticharoen P, Petmitr S, Weinfeld M, Chavalitshewinkoon-Petmitr P. Characterization of Plasmodium falciparum ATP-dependent DNA helicase RuvB3. Malaria Journal. 15: 526. PMID 27809838 DOI: 10.1186/S12936-016-1573-2  0.376
2016 Jiang B, Glover JN, Weinfeld M. Neurological disorders associated with DNA strand-break processing enzymes. Mechanisms of Ageing and Development. PMID 27470939 DOI: 10.1016/J.Mad.2016.07.009  0.469
2016 Ouenzar F, Hendzel MJ, Weinfeld M. Shuttling towards a predictive assay for radiotherapy Translational Cancer Research. 5. DOI: 10.21037/10117  0.381
2015 Yang N, Gilman P, Mirzayans R, Sun X, Touret N, Weinfeld M, Goping IS. Characterization of the apoptotic response induced by the cyanine dye D112: a potentially selective anti-cancer compound. Plos One. 10: e0125381. PMID 25927702 DOI: 10.1371/Journal.Pone.0125381  0.328
2015 Enns L, Rasouli-Nia A, Hendzel M, Marples B, Weinfeld M. Association of ATM activation and DNA repair with induced radioresistance after low-dose irradiation. Radiation Protection Dosimetry. 166: 131-6. PMID 25904696 DOI: 10.1093/Rpd/Ncv203  0.557
2015 Abdou I, Poirier GG, Hendzel MJ, Weinfeld M. DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair. Nucleic Acids Research. 43: 875-92. PMID 25539916 DOI: 10.1093/Nar/Gku1307  0.549
2015 Chen B, Liu Q, Popowich A, Shen S, Yan X, Zhang Q, Li XF, Weinfeld M, Cullen WR, Le XC. Therapeutic and analytical applications of arsenic binding to proteins. Metallomics : Integrated Biometal Science. 7: 39-55. PMID 25356501 DOI: 10.1039/C4Mt00222A  0.311
2015 Crosley P, Agopsowicz K, Weinfeld M, Hitt M. Abstract POSTER-THER-1410: Combining small molecule drugs and standard chemotherapy for treatment of granulosa cell tumour cells Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Ovcasymp14-Poster-Ther-1410  0.369
2014 Sahin B, Fife J, Parmar MB, Valencia-Serna J, Gul-Uluda? H, Jiang X, Weinfeld M, Lavasanifar A, Uluda? H. siRNA therapy in cutaneous T-cell lymphoma cells using polymeric carriers. Biomaterials. 35: 9382-94. PMID 25128374 DOI: 10.1016/J.Biomaterials.2014.07.029  0.354
2014 Zereshkian A, Leyton JV, Cai Z, Bergstrom D, Weinfeld M, Reilly RM. The human polynucleotide kinase/phosphatase (hPNKP) inhibitor A12B4C3 radiosensitizes human myeloid leukemia cells to Auger electron-emitting anti-CD123 ¹¹¹In-NLS-7G3 radioimmunoconjugates. Nuclear Medicine and Biology. 41: 377-83. PMID 24637100 DOI: 10.1016/J.Nucmedbio.2014.02.003  0.406
2013 Mereniuk TR, El Gendy MA, Mendes-Pereira AM, Lord CJ, Ghosh S, Foley E, Ashworth A, Weinfeld M. Synthetic lethal targeting of PTEN-deficient cancer cells using selective disruption of polynucleotide kinase/phosphatase. Molecular Cancer Therapeutics. 12: 2135-44. PMID 23883586 DOI: 10.1158/1535-7163.Mct-12-1093  0.779
2013 Shen S, Li XF, Cullen WR, Weinfeld M, Le XC. Arsenic binding to proteins. Chemical Reviews. 113: 7769-92. PMID 23808632 DOI: 10.1021/Cr300015C  0.322
2013 Shen S, Wang C, Weinfeld M, Le XC. Inhibition of nucleotide excision repair by arsenic Chinese Science Bulletin. 58: 214-221. DOI: 10.1007/S11434-012-5439-X  0.526
2012 Mereniuk TR, Maranchuk RA, Schindler A, Penner-Chea J, Freschauf GK, Hegazy S, Lai R, Foley E, Weinfeld M. Genetic screening for synthetic lethal partners of polynucleotide kinase/phosphatase: potential for targeting SHP-1-depleted cancers. Cancer Research. 72: 5934-44. PMID 22962271 DOI: 10.1158/0008-5472.Can-12-0939  0.792
2012 Kashkina E, Qi T, Weinfeld M, Young D. Polynucleotide kinase/phosphatase, Pnk1, is involved in base excision repair in Schizosaccharomyces pombe. Dna Repair. 11: 676-83. PMID 22748672 DOI: 10.1016/J.Dnarep.2012.06.001  0.563
2012 Tahbaz N, Subedi S, Weinfeld M. Role of polynucleotide kinase/phosphatase in mitochondrial DNA repair. Nucleic Acids Research. 40: 3484-95. PMID 22210862 DOI: 10.1093/Nar/Gkr1245  0.51
2011 Zolner AE, Abdou I, Ye R, Mani RS, Fanta M, Yu Y, Douglas P, Tahbaz N, Fang S, Dobbs T, Wang C, Morrice N, Hendzel MJ, Weinfeld M, Lees-Miller SP. Phosphorylation of polynucleotide kinase/ phosphatase by DNA-dependent protein kinase and ataxia-telangiectasia mutated regulates its association with sites of DNA damage. Nucleic Acids Research. 39: 9224-37. PMID 21824916 DOI: 10.1093/Nar/Gkr647  0.579
2011 Siribal S, Weinfeld M, Karimi-Busheri F, Mark Glover JN, Bernstein NK, Aceytuno D, Chavalitshewinkoon-Petmitr P. Molecular characterization of Plasmodium falciparum putative polynucleotide kinase/phosphatase. Molecular and Biochemical Parasitology. 180: 1-7. PMID 21821066 DOI: 10.1016/J.Molbiopara.2011.06.007  0.562
2011 Hammel M, Rey M, Yu Y, Mani RS, Classen S, Liu M, Pique ME, Fang S, Mahaney BL, Weinfeld M, Schriemer DC, Lees-Miller SP, Tainer JA. XRCC4 protein interactions with XRCC4-like factor (XLF) create an extended grooved scaffold for DNA ligation and double strand break repair. The Journal of Biological Chemistry. 286: 32638-50. PMID 21775435 DOI: 10.1074/Jbc.M111.272641  0.519
2011 Weinfeld M, Mani RS, Abdou I, Aceytuno RD, Glover JN. Tidying up loose ends: the role of polynucleotide kinase/phosphatase in DNA strand break repair. Trends in Biochemical Sciences. 36: 262-71. PMID 21353781 DOI: 10.1016/J.Tibs.2011.01.006  0.595
2011 Taleei R, Weinfeld M, Nikjoo H. A kinetic model of single-strand annealing for the repair of DNA double-strand breaks. Radiation Protection Dosimetry. 143: 191-5. PMID 21183536 DOI: 10.1093/Rpd/Ncq535  0.454
2010 Mani RS, Yu Y, Fang S, Lu M, Fanta M, Zolner AE, Tahbaz N, Ramsden DA, Litchfield DW, Lees-Miller SP, Weinfeld M. Dual modes of interaction between XRCC4 and polynucleotide kinase/phosphatase: implications for nonhomologous end joining. The Journal of Biological Chemistry. 285: 37619-29. PMID 20852255 DOI: 10.1074/Jbc.M109.058719  0.431
2010 Freschauf GK, Mani RS, Mereniuk TR, Fanta M, Virgen CA, Dianov GL, Grassot JM, Hall DG, Weinfeld M. Mechanism of action of an imidopiperidine inhibitor of human polynucleotide kinase/phosphatase. The Journal of Biological Chemistry. 285: 2351-60. PMID 19940137 DOI: 10.1074/Jbc.M109.055764  0.79
2009 Freschauf GK, Karimi-Busheri F, Ulaczyk-Lesanko A, Mereniuk TR, Ahrens A, Koshy JM, Rasouli-Nia A, Pasarj P, Holmes CF, Rininsland F, Hall DG, Weinfeld M. Identification of a small molecule inhibitor of the human DNA repair enzyme polynucleotide kinase/phosphatase. Cancer Research. 69: 7739-46. PMID 19773431 DOI: 10.1158/0008-5472.Can-09-1805  0.778
2009 Wang H, Lu M, Tang MS, Van Houten B, Ross JB, Weinfeld M, Le XC. DNA wrapping is required for DNA damage recognition in the Escherichia coli DNA nucleotide excision repair pathway. Proceedings of the National Academy of Sciences of the United States of America. 106: 12849-54. PMID 19549864 DOI: 10.1073/Pnas.0902281106  0.569
2009 Charoensuk V, Gati WP, Weinfeld M, Le XC. Differential cytotoxic effects of arsenic compounds in human acute promyelocytic leukemia cells. Toxicology and Applied Pharmacology. 239: 64-70. PMID 19465042 DOI: 10.1016/J.Taap.2009.05.016  0.318
2009 Naranmandura H, Ogra Y, Iwata K, Lee J, Suzuki KT, Weinfeld M, Le XC. Evidence for toxicity differences between inorganic arsenite and thioarsenicals in human bladder cancer cells. Toxicology and Applied Pharmacology. 238: 133-40. PMID 19442679 DOI: 10.1016/J.Taap.2009.05.006  0.309
2009 Yan H, Wang N, Weinfeld M, Cullen WR, Le XC. Identification of arsenic-binding proteins in human cells by affinity chromatography and mass spectrometry. Analytical Chemistry. 81: 4144-52. PMID 19371058 DOI: 10.1021/Ac900352K  0.317
2009 LeBlanc A, Shen S, Lew K, Weinfeld M, Le XC. Detection of benzo(a)pyrene diol epoxide-DNA adducts in mononuclear white blood cells by CE immunoassay and its application to studying the effect of glutathione depletion. Electrophoresis. 30: 1558-63. PMID 19343725 DOI: 10.1002/Elps.200800391  0.537
2009 Shen S, Lee J, Cullen WR, Le XC, Weinfeld M. Arsenite and its mono- and dimethylated trivalent metabolites enhance the formation of benzo[a]pyrene diol epoxide-DNA adducts in Xeroderma pigmentosum complementation group A cells. Chemical Research in Toxicology. 22: 382-90. PMID 19146383 DOI: 10.1021/Tx800335P  0.55
2008 Bernstein NK, Karimi-Busheri F, Rasouli-Nia A, Mani R, Dianov G, Glover JN, Weinfeld M. Polynucleotide kinase as a potential target for enhancing cytotoxicity by ionizing radiation and topoisomerase I inhibitors. Anti-Cancer Agents in Medicinal Chemistry. 8: 358-67. PMID 18473721 DOI: 10.2174/187152008784220311  0.586
2008 Shen S, Lee J, Weinfeld M, Le XC. Attenuation of DNA damage-induced p53 expression by arsenic: a possible mechanism for arsenic co-carcinogenesis. Molecular Carcinogenesis. 47: 508-18. PMID 18085531 DOI: 10.1002/Mc.20406  0.489
2007 Mani RS, Fanta M, Karimi-Busheri F, Silver E, Virgen CA, Caldecott KW, Cass CE, Weinfeld M. XRCC1 stimulates polynucleotide kinase by enhancing its damage discrimination and displacement from DNA repair intermediates. The Journal of Biological Chemistry. 282: 28004-13. PMID 17650498 DOI: 10.1074/jbc.M704867200  0.488
2007 Karimi-Busheri F, Rasouli-Nia A, Allalunis-Turner J, Weinfeld M. Human polynucleotide kinase participates in repair of DNA double-strand breaks by nonhomologous end joining but not homologous recombination. Cancer Research. 67: 6619-25. PMID 17638872 DOI: 10.1158/0008-5472.CAN-07-0480  0.454
2007 Datta K, Weinfeld M, Neumann RD, Winters TA. Determination and analysis of site-specific 125I decay-induced DNA double-strand break end-group structures. Radiation Research. 167: 152-66. PMID 17390723 DOI: 10.1667/Rr0629.1  0.479
2007 Abbasi M, Uludag H, Incani V, Olson C, Lin X, Clements BA, Rutkowski D, Ghahary A, Weinfeld M. Palmitic acid-modified poly-L-lysine for non-viral delivery of plasmid DNA to skin fibroblasts. Biomacromolecules. 8: 1059-63. PMID 17335285 DOI: 10.1021/Bm060940X  0.471
2006 Shen S, Lee J, Sun X, Wang H, Weinfeld M, Le XC. Elevation of cellular BPDE uptake by human cells: a possible factor contributing to co-carcinogenicity by arsenite. Environmental Health Perspectives. 114: 1832-7. PMID 17185271 DOI: 10.1289/Ehp.9284  0.492
2006 Das A, Wiederhold L, Leppard JB, Kedar P, Prasad R, Wang H, Boldogh I, Karimi-Busheri F, Weinfeld M, Tomkinson AE, Wilson SH, Mitra S, Hazra TK. NEIL2-initiated, APE-independent repair of oxidized bases in DNA: Evidence for a repair complex in human cells. Dna Repair. 5: 1439-48. PMID 16982218 DOI: 10.1016/J.Dnarep.2006.07.003  0.44
2006 Audebert M, Salles B, Weinfeld M, Calsou P. Involvement of polynucleotide kinase in a poly(ADP-ribose) polymerase-1-dependent DNA double-strand breaks rejoining pathway. Journal of Molecular Biology. 356: 257-65. PMID 16364363 DOI: 10.1016/J.Jmb.2005.11.028  0.582
2005 Williams RS, Bernstein N, Lee MS, Rakovszky ML, Cui D, Green R, Weinfeld M, Glover JN. Structural basis for phosphorylation-dependent signaling in the DNA-damage response. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 83: 721-7. PMID 16333323 DOI: 10.1139/O05-153  0.532
2005 Parsons JL, Dianova II, Boswell E, Weinfeld M, Dianov GL. End-damage-specific proteins facilitate recruitment or stability of X-ray cross-complementing protein 1 at the sites of DNA single-strand break repair. The Febs Journal. 272: 5753-63. PMID 16279940 DOI: 10.1111/J.1742-4658.2005.04962.X  0.572
2005 Barker S, Weinfeld M, Zheng J, Li L, Murray D. Identification of mammalian proteins cross-linked to DNA by ionizing radiation. The Journal of Biological Chemistry. 280: 33826-38. PMID 16093242 DOI: 10.1074/Jbc.M502477200  0.502
2005 Barker S, Murray D, Zheng J, Li L, Weinfeld M. A method for the isolation of covalent DNA-protein crosslinks suitable for proteomics analysis. Analytical Biochemistry. 344: 204-15. PMID 16091282 DOI: 10.1016/J.Ab.2005.06.039  0.487
2005 Barker S, Weinfeld M, Murray D. DNA-protein crosslinks: their induction, repair, and biological consequences. Mutation Research. 589: 111-35. PMID 15795165 DOI: 10.1016/J.Mrrev.2004.11.003  0.508
2005 Bernstein NK, Williams RS, Rakovszky ML, Cui D, Green R, Karimi-Busheri F, Mani RS, Galicia S, Koch CA, Cass CE, Durocher D, Weinfeld M, Glover JN. The molecular architecture of the mammalian DNA repair enzyme, polynucleotide kinase. Molecular Cell. 17: 657-70. PMID 15749016 DOI: 10.1016/J.Molcel.2005.02.012  0.361
2005 El-Khamisy SF, Saifi GM, Weinfeld M, Johansson F, Helleday T, Lupski JR, Caldecott KW. Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1. Nature. 434: 108-13. PMID 15744309 DOI: 10.1038/Nature03314  0.531
2004 Mani RS, Karimi-Busheri F, Fanta M, Caldecott KW, Cass CE, Weinfeld M. Biophysical characterization of human XRCC1 and its binding to damaged and undamaged DNA. Biochemistry. 43: 16505-14. PMID 15610045 DOI: 10.1021/bi048615m  0.375
2004 Koch CA, Agyei R, Galicia S, Metalnikov P, O'Donnell P, Starostine A, Weinfeld M, Durocher D. Xrcc4 physically links DNA end processing by polynucleotide kinase to DNA ligation by DNA ligase IV. The Embo Journal. 23: 3874-85. PMID 15385968 DOI: 10.1038/Sj.Emboj.7600375  0.576
2004 Wiederhold L, Leppard JB, Kedar P, Karimi-Busheri F, Rasouli-Nia A, Weinfeld M, Tomkinson AE, Izumi T, Prasad R, Wilson SH, Mitra S, Hazra TK. AP endonuclease-independent DNA base excision repair in human cells. Molecular Cell. 15: 209-20. PMID 15260972 DOI: 10.1016/J.Molcel.2004.06.003  0.463
2004 Rasouli-Nia A, Karimi-Busheri F, Weinfeld M. Stable down-regulation of human polynucleotide kinase enhances spontaneous mutation frequency and sensitizes cells to genotoxic agents. Proceedings of the National Academy of Sciences of the United States of America. 101: 6905-10. PMID 15100409 DOI: 10.1073/pnas.0400099101  0.511
2003 Mei N, Lee J, Sun X, Xing JZ, Hanson J, Le XC, Weinfeld M. Genetic predisposition to the cytotoxicity of arsenic: the role of DNA damage and ATM. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 2310-2. PMID 14563695 DOI: 10.1096/Fj.02-0093Fje  0.515
2003 Mani RS, Karimi-Busheri F, Fanta M, Cass CE, Weinfeld M. Spectroscopic studies of DNA and ATP binding to human polynucleotide kinase: evidence for a ternary complex. Biochemistry. 42: 12077-84. PMID 14556639 DOI: 10.1021/Bi030127B  0.483
2003 Plo I, Liao ZY, Barceló JM, Kohlhagen G, Caldecott KW, Weinfeld M, Pommier Y. Association of XRCC1 and tyrosyl DNA phosphodiesterase (Tdp1) for the repair of topoisomerase I-mediated DNA lesions. Dna Repair. 2: 1087-100. PMID 13679147 DOI: 10.1016/S1568-7864(03)00116-2  0.587
2003 Wang H, Lu M, Mei N, Lee J, Weinfeld M, Le XC. Immunoassays using capillary electrophoresis laser induced fluorescence detection for DNA adducts Analytica Chimica Acta. 500: 13-20. DOI: 10.1016/S0003-2670(03)00631-7  0.54
2002 Buchko GW, Weinfeld M. DNA-targeted 2-nitroimidazoles: studies of the influence of the phenanthridine-linked nitroimidazoles, 2-NLP-3 and 2-NLP-4, on DNA damage induced by ionizing radiation. Radiation Research. 158: 302-10. PMID 12175307 DOI: 10.1667/0033-7587(2002)158[0302:Dtnsot]2.0.Co;2  0.571
2002 Wang H, Xing J, Tan W, Lam M, Carnelley T, Weinfeld M, Le XC. Binding stoichiometry of DNA adducts with antibody studied by capillary electrophoresis and laser-induced fluorescence. Analytical Chemistry. 74: 3714-9. PMID 12175158 DOI: 10.1021/Ac0201979  0.353
2002 Takao M, Kanno S, Shiromoto T, Hasegawa R, Ide H, Ikeda S, Sarker AH, Seki S, Xing JZ, Le XC, Weinfeld M, Kobayashi K, Miyazaki J, Muijtjens M, Hoeijmakers JH, et al. Novel nuclear and mitochondrial glycosylases revealed by disruption of the mouse Nth1 gene encoding an endonuclease III homolog for repair of thymine glycols. The Embo Journal. 21: 3486-93. PMID 12093749 DOI: 10.1093/Emboj/Cdf350  0.45
2002 Chappell C, Hanakahi LA, Karimi-Busheri F, Weinfeld M, West SC. Involvement of human polynucleotide kinase in double-strand break repair by non-homologous end joining. The Embo Journal. 21: 2827-32. PMID 12032095 DOI: 10.1093/Emboj/21.11.2827  0.478
2002 Weinfeld M, Xing JZ, Lee J, Leadon SA, Le XC. Immunofluorescence detection of radiation-induced DNA base damage. Military Medicine. 167: 2-4. PMID 11873503 DOI: 10.1093/Milmed/167.Suppl_1.2  0.522
2002 Meijer M, Karimi-Busheri F, Huang TY, Weinfeld M, Young D. Pnk1, a DNA kinase/phosphatase required for normal response to DNA damage by gamma-radiation or camptothecin in Schizosaccharomyces pombe. The Journal of Biological Chemistry. 277: 4050-5. PMID 11729194 DOI: 10.1074/jbc.M109383200  0.508
2001 Cloutier JF, Drouin R, Weinfeld M, O'Connor TR, Castonguay A. Characterization and mapping of DNA damage induced by reactive metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) at nucleotide resolution in human genomic DNA. Journal of Molecular Biology. 313: 539-57. PMID 11676538 DOI: 10.1006/Jmbi.2001.4997  0.57
2001 Mani RS, Karimi-Busheri F, Cass CE, Weinfeld M. Physical properties of human polynucleotide kinase: hydrodynamic and spectroscopic studies. Biochemistry. 40: 12967-73. PMID 11669634 DOI: 10.1021/Bi011383W  0.412
2001 Fanta M, Zhang H, Bernstein N, Glover M, Karimi-Busheri F, Weinfeld M. Production, characterization, and epitope mapping of monoclonal antibodies against human polydeoxyribonucleotide kinase. Hybridoma. 20: 237-242. PMID 11604109 DOI: 10.1089/027245701753179811  0.453
2001 Weinfeld M, Rasouli-Nia A, Chaudhry MA, Britten RA. Response of base excision repair enzymes to complex DNA lesions. Radiation Research. 156: 584-9. PMID 11604076 DOI: 10.1667/0033-7587(2001)156[0584:Robere]2.0.Co;2  0.502
2001 Weinfeld M, Xing JZ, Lee J, Leadon SA, Cooper PK, Le XC. Factors influencing the removal of thymine glycol from DNA in γ-irradiated human cells Progress in Nucleic Acid Research and Molecular Biology. 68: 139-149. PMID 11554293 DOI: 10.1016/S0079-6603(01)68096-6  0.496
2001 Weinfeld M. Session 3 Complexities of BER Progress in Nucleic Acid Research and Molecular Biology. 68: 125-127. PMID 11554291 DOI: 10.1016/S0079-6603(01)68094-2  0.506
2001 Tan WG, Carnelley TJ, Murphy P, Wang H, Lee J, Barker S, Weinfeld M, Le XC. Detection of DNA adducts of benzo[a]pyrene using immunoelectrophoresis with laser-induced fluorescence: Analysis of A549 cells Journal of Chromatography A. 924: 377-386. PMID 11521887 DOI: 10.1016/S0021-9673(01)00987-6  0.47
2001 Xing JZ, Carnelley T, Lee J, Watson WP, Booth E, Weinfeld M, Le XC. Assay for DNA damage using immunochemical recognition and capillary electrophoresis. Methods of Molecular Biology. 162: 419-428. PMID 11217352 DOI: 10.1385/1-59259-055-1:419  0.525
2000 Xing JZ, Lee J, Leadon SA, Weinfeld M, Le XC. Measuring DNA damage using capillary electrophoresis with laser-induced fluorescence detection. Methods. 22: 157-163. PMID 11020330 DOI: 10.1006/Meth.2000.1056  0.507
1999 D'Silva I, Pelletier JD, Lagueux J, D'Amours D, Chaudhry MA, Weinfeld M, Lees-Miller SP, Poirier GG. Relative affinities of poly(ADP-ribose) polymerase and DNA-dependent protein kinase for DNA strand interruptions. Biochimica Et Biophysica Acta. 1430: 119-26. PMID 10082940 DOI: 10.1016/S0167-4838(98)00278-7  0.576
1999 Izumi T, Malecki J, Chaudhry MA, Weinfeld M, Hill JH, Lee JC, Mitra S. Intragenic suppression of an active site mutation in the human apurinic/apyrimidinic endonuclease. Journal of Molecular Biology. 287: 47-57. PMID 10074406 DOI: 10.1006/Jmbi.1999.2573  0.351
1999 Chaudhry MA, Dedon PC, Wilson DM, Demple B, Weinfeld M. Removal by human apurinic/apyrimidinic endonuclease 1 (Ape 1) and Escherichia coli exonuclease III of 3'-phosphoglycolates from DNA treated with neocarzinostatin, calicheamicin, and γ-radiation Biochemical Pharmacology. 57: 531-538. PMID 9952316 DOI: 10.1016/S0006-2952(98)00327-X  0.527
1998 Le XC, Xing JZ, Lee J, Leadon SA, Weinfeld M. Inducible repair of thymine glycol detected by an ultrasensitive assay for DNA damage. Science. 280: 1066-1069. PMID 9582118 DOI: 10.1126/Science.280.5366.1066  0.505
1997 Weinfeld M, Lee J, Ruiqi G, Karimi-Busheri F, Chen D, Allalunis-Turner J. Use of a postlabelling assay to examine the removal of radiation-induced DNA lesions by purified enzymes and human cell extracts Mutation Research. 378: 127-137. PMID 9288891 DOI: 10.1016/S0027-5107(97)00103-6  0.44
1997 Weinfeld M, Chaudhry MA, D'Amours D, Pelletier JD, Poirier GG, Povirk LF, Lees-Miller SP. Interaction of DNA-dependent protein kinase and poly(ADP-ribose) polymerase with radiation-induced DNA strand breaks. Radiation Research. 148: 22-8. PMID 9216614 DOI: 10.2307/3579534  0.589
1997 Aubin RA, Weinfeld M, Taghavi M, Mirzayans R, Paterson MC. Highly Effective Delivery of Foreign DNA to Adherent Cells via Polybrene/DMSO-Assisted Gene Transfer Methods of Molecular Biology. 62: 319-342. PMID 9108531 DOI: 10.1385/0-89603-480-1:319  0.46
1996 Wagner JR, Blount BC, Weinfeld M. Excision of oxidative cytosine modifications from γ-irradiated DNA by Escherichia coll endonuclease III and human whole-cell extracts Analytical Biochemistry. 233: 76-86. PMID 8789150 DOI: 10.1006/Abio.1996.0010  0.458
1995 Buchko GW, Wagner JR, Cadet J, Raoul S, Weinfeld M. Methylene blue-mediated photooxidation of 7,8-dihydro-8-oxo-2'-deoxyguanosine. Biochimica Et Biophysica Acta. 1263: 17-24. PMID 7632729 DOI: 10.1016/0167-4781(95)00078-U  0.388
1995 Chaudhry MA, Weinfeld M. Induction of double-strand breaks by S1 nuclease, mung bean nuclease and nuclease P1 in DNA containing abasic sites and nicks Nucleic Acids Research. 23: 3805-3809. PMID 7479020 DOI: 10.1093/Nar/23.19.3805  0.477
1994 Aubin RA, Weinfeld M, Mirzayans R, Paterson MC. Polybrene/DMSO-assisted gene transfer. Generating stable transfectants with nanogram amounts of DNA. Molecular Biotechnology. 1: 29-48. PMID 7859152 DOI: 10.1007/Bf02821509  0.474
1993 Cadet J, Weinfeld M. Detecting DNA damage. Analytical Chemistry. 65. PMID 8372974 DOI: 10.1021/Ac00063A001  0.51
1991 Aubin R, Weinfeld M, Paterson MC. Polybrene/DMSOAssisted Gene Transfer. Methods of Molecular Biology. 7: 35-43. PMID 21416345 DOI: 10.1385/0-89603-178-0:35  0.492
1991 Aubin R, Weinfeld M, Paterson MC. Preparation of Recombinant Plasmid DNA for DNA-Mediated Gene Transfer Methods of Molecular Biology. 7: 3-13. PMID 21416342 DOI: 10.1385/0-89603-178-0:3  0.457
1991 Weinfeld M, Soderlind KJM. 32P-postlabeling detection of radiation-induced DNA damage: identification and estimation of thymine glycols and phosphoglycolate termini. Biochemistry. 30: 1091-1097. PMID 1846559 DOI: 10.1021/Bi00218A031  0.518
1990 Weinfeld M, Liuzzi M, Paterson MC. Response of phage T4 polynucleotide kinase toward dinucleotides containing apurinic sites: design of a 32P-postlabeling assay for apurinic sites in DNA. Biochemistry. 29: 1737-1743. PMID 2158812 DOI: 10.1021/Bi00459A011  0.5
1988 Weinfeld M, Paterson MC. DNA cyclobutane pyrimidine dimers with a cleaved internal phosphodiester bond can be photoenzymatically reversed by Escherichia coli PhrB photolyase. Nucleic Acids Research. 16: 5693-5693. PMID 3290858 DOI: 10.1093/Nar/16.12.5693  0.453
1988 Aubin RJ, Weinfeld M, Paterson MC. Factors influencing efficiency and reproducibility of polybrene-assisted gene transfer. Somatic Cell and Molecular Genetics. 14: 155-167. PMID 3162336 DOI: 10.1007/Bf01534401  0.475
1987 Liuzzi M, Weinfeld M, Paterson MC. Selective inhibition by methoxyamine of the apurinic/apyrimidinic endonuclease activity associated with pyrimidine dimer-DNA glycosylases from Micrococcus luteus and bacteriophage T4. Biochemistry. 26: 3315-3321. PMID 2443160 DOI: 10.1021/Bi00386A011  0.498
1986 Weinfeld M, Livingston DC. Synthesis and properties of oligodeoxyribonucleotides containing an ethylated internucleotide phosphate. Biochemistry. 25: 5083-5091. PMID 3768334 DOI: 10.1021/Bi00366A016  0.539
1986 Weinfeld M, Gentner NE, Johnson LD, Paterson MC. Photoreversal-dependent release of thymidine and thymidine monophosphate from pyrimidine dimer-containing DNA excision fragments isolated from ultraviolet-damaged human fibroblasts. Biochemistry. 25: 2656-64. PMID 3521740 DOI: 10.1021/Bi00357A055  0.445
1985 Weinfeld M, Drake AF, Saunders JK, Paterson MC. Stereospecific removal of methyl phosphotriesters from DNA by an Escherichia coli ada+ extract Nucleic Acids Research. 13: 7067-7077. PMID 3903661 DOI: 10.1093/Nar/13.19.7067  0.449
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