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Ewan St. John Smith, MPharmacol., PhD - Publications

Affiliations: 
University of Cambridge, Cambridge, England, United Kingdom 
Area:
Sensory transduction, ion channels, naked mole-rats, pain
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24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Prato V, Taberner FJ, Hockley JRF, Callejo G, Arcourt A, Tazir B, Hammer L, Schad P, Heppenstall PA, Smith ES, Lechner SG. Functional and Molecular Characterization of Mechanoinsensitive "Silent" Nociceptors. Cell Reports. 21: 3102-3115. PMID 29241539 DOI: 10.1016/J.Celrep.2017.11.066  0.797
2016 Schuhmacher LN, Smith ES. Expression of acid-sensing ion channels and selection of reference genes in mouse and naked mole rat. Molecular Brain. 9: 97. PMID 27964758 DOI: 10.1186/S13041-016-0279-2  0.802
2016 Wetzel C, Pifferi S, Picci C, Gök C, Hoffmann D, Bali KK, Lampe A, Lapatsina L, Fleischer R, Smith ES, Bégay V, Moroni M, Estebanez L, Kühnemund J, Walcher J, et al. Small-molecule inhibition of STOML3 oligomerization reverses pathological mechanical hypersensitivity. Nature Neuroscience. PMID 27941788 DOI: 10.1038/Nn.4454  0.736
2016 Omerbašić D, Smith ES, Moroni M, Homfeld J, Eigenbrod O, Bennett NC, Reznick J, Faulkes CG, Selbach M, Lewin GR. Hypofunctional TrkA Accounts for the Absence of Pain Sensitization in the African Naked Mole-Rat. Cell Reports. 17: 748-758. PMID 27732851 DOI: 10.1016/J.Celrep.2016.09.035  0.704
2016 da Silva Serra I, Husson Z, Bartlett JD, Smith ES. Characterization of cutaneous and articular sensory neurons. Molecular Pain. 12. PMID 27030722 DOI: 10.1177/1744806916636387  0.788
2015 Schuhmacher LN, Srivats S, Smith ES. Structural domains underlying the activation of acid-sensing ion channel 2a. Molecular Pharmacology. 87: 561-71. PMID 25583083 DOI: 10.1124/Mol.114.096909  0.783
2015 Omerbaši? D, Schuhmacher LN, Bernal Sierra YA, Smith ES, Lewin GR. ASICs and mammalian mechanoreceptor function. Neuropharmacology. 94: 80-86. PMID 25528740 DOI: 10.1016/J.Neuropharm.2014.12.007  0.813
2014 Rahman T, Smith ES. In silico assessment of interaction of sea anemone toxin APETx2 and acid sensing ion channel 3. Biochemical and Biophysical Research Communications. 450: 384-9. PMID 24942880 DOI: 10.1016/j.bbrc.2014.05.130  0.412
2014 Lewin GR, Lechner SG, Smith ES. Nerve growth factor and nociception: from experimental embryology to new analgesic therapy. Handbook of Experimental Pharmacology. 220: 251-82. PMID 24668476 DOI: 10.1007/978-3-642-45106-5_10  0.799
2014 Kozlenkov A, Lapatsina L, Lewin GR, Smith ES. Subunit-specific inhibition of acid sensing ion channels by stomatin-like protein 1. The Journal of Physiology. 592: 557-69. PMID 24247984 DOI: 10.1113/jphysiol.2013.258657  0.752
2013 Smith ES, Martinez-Velazquez L, Ringstad N. A chemoreceptor that detects molecular carbon dioxide. The Journal of Biological Chemistry. 288: 37071-81. PMID 24240097 DOI: 10.1074/jbc.M113.517367  0.696
2012 Brand J, Smith ES, Schwefel D, Lapatsina L, Poole K, OmerbaÅ¡ić D, Kozlenkov A, Behlke J, Lewin GR, Daumke O. A stomatin dimer modulates the activity of acid-sensing ion channels. The Embo Journal. 31: 3635-46. PMID 22850675 DOI: 10.1038/Emboj.2012.203  0.738
2012 Stock K, Kumar J, Synowitz M, Petrosino S, Imperatore R, Smith ES, Wend P, Purfürst B, Nuber UA, Gurok U, Matyash V, Wälzlein JH, Chirasani SR, Dittmar G, Cravatt BF, et al. Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1. Nature Medicine. 18: 1232-8. PMID 22820645 DOI: 10.1038/Nm.2827  0.639
2012 Lapatsina L, Jira JA, Smith ES, Poole K, Kozlenkov A, Bilbao D, Lewin GR, Heppenstall PA. Regulation of ASIC channels by a stomatin/STOML3 complex located in a mobile vesicle pool in sensory neurons. Open Biology. 2: 120096. PMID 22773952 DOI: 10.1098/Rsob.120096  0.808
2011 Smith ES, OmerbaÅ¡ić D, Lechner SG, Anirudhan G, Lapatsina L, Lewin GR. The molecular basis of acid insensitivity in the African naked mole-rat. Science (New York, N.Y.). 334: 1557-60. PMID 22174253 DOI: 10.1126/Science.1213760  0.769
2011 Lechner SG, Markworth S, Poole K, Smith ES, Lapatsina L, Frahm S, May M, Pischke S, Suzuki M, Ibañez-Tallon I, Luft FC, Jordan J, Lewin GR. The molecular and cellular identity of peripheral osmoreceptors. Neuron. 69: 332-44. PMID 21262470 DOI: 10.1016/J.Neuron.2010.12.028  0.748
2010 Brand A, Smith ES, Lewin GR, Park TJ. Functional neurokinin and NMDA receptor activity in an animal naturally lacking substance P: the naked mole-rat. Plos One. 5: e15162. PMID 21200438 DOI: 10.1371/journal.pone.0015162  0.713
2010 Smith ES, Blass GR, Lewin GR, Park TJ. Absence of histamine-induced itch in the African naked mole-rat and "rescue" by Substance P. Molecular Pain. 6: 29. PMID 20497578 DOI: 10.1186/1744-8069-6-29  0.777
2010 Stürzebecher AS, Hu J, Smith ES, Frahm S, Santos-Torres J, Kampfrath B, Auer S, Lewin GR, Ibañez-Tallon I. An in vivo tethered toxin approach for the cell-autonomous inactivation of voltage-gated sodium channel currents in nociceptors. The Journal of Physiology. 588: 1695-707. PMID 20308253 DOI: 10.1113/Jphysiol.2010.187112  0.749
2009 Smith ES, Lewin GR. Nociceptors: a phylogenetic view. Journal of Comparative Physiology. a, Neuroethology, Sensory, Neural, and Behavioral Physiology. 195: 1089-106. PMID 19830434 DOI: 10.1007/s00359-009-0482-z  0.705
2008 Park TJ, Lu Y, Jüttner R, Smith ES, Hu J, Brand A, Wetzel C, Milenkovic N, Erdmann B, Heppenstall PA, Laurito CE, Wilson SP, Lewin GR. Selective inflammatory pain insensitivity in the African naked mole-rat (Heterocephalus glaber). Plos Biology. 6: e13. PMID 18232734 DOI: 10.1371/Journal.Pbio.0060013  0.809
2007 Cadiou H, Studer M, Jones NG, Smith ES, Ballard A, McMahon SB, McNaughton PA. Modulation of acid-sensing ion channel activity by nitric oxide. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 13251-60. PMID 18045919 DOI: 10.1523/JNEUROSCI.2135-07.2007  0.744
2007 Smith ES, Zhang X, Cadiou H, McNaughton PA. Proton binding sites involved in the activation of acid-sensing ion channel ASIC2a. Neuroscience Letters. 426: 12-7. PMID 17881127 DOI: 10.1016/j.neulet.2007.07.047  0.603
2007 Smith ES, Cadiou H, McNaughton PA. Arachidonic acid potentiates acid-sensing ion channels in rat sensory neurons by a direct action. Neuroscience. 145: 686-98. PMID 17258862 DOI: 10.1016/j.neuroscience.2006.12.024  0.679
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