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Kenneth V. Mills, Ph.D. - Publications

Affiliations: 
2001 Harvard University, Cambridge, MA, United States 
Area:
Biochemistry
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32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Yalala VR, Lynch AK, Mills KV. Conditional Alternative Protein Splicing Promoted by Inteins from . Biochemistry. 61: 294-302. PMID 35073064 DOI: 10.1021/acs.biochem.1c00788  0.421
2021 Wall DA, Tarrant SP, Wang C, Mills KV, Lennon CW. Intein Inhibitors as Novel Antimicrobials: Protein Splicing in Human Pathogens, Screening Methods, and Off-Target Considerations. Frontiers in Molecular Biosciences. 8: 752824. PMID 34692773 DOI: 10.3389/fmolb.2021.752824  0.353
2021 Williams JE, Jaramillo MV, Li Z, Zhao J, Wang C, Li H, Mills KV. An alternative domain-swapped structure of the Pyrococcus horikoshii PolII mini-intein. Scientific Reports. 11: 11680. PMID 34083592 DOI: 10.1038/s41598-021-91090-w  0.319
2020 Robinzon S, Cawood AR, Ruiz MA, Gophna U, Altman-Price N, Mills KV. Protein Splicing Activity of the PolB-c Intein Is Sensitive to Homing Endonuclease Domain Mutations. Biochemistry. 59: 3359-3367. PMID 32822531 DOI: 10.1021/Acs.Biochem.0C00512  0.491
2020 Chiarolanzio KC, Pusztay JM, Chavez A, Zhao J, Xie J, Wang C, Mills KV. Allosteric influence of extremophile hairpin motif mutations on the protein splicing activity of a hyperthermophilic intein. Biochemistry. PMID 32559373 DOI: 10.1021/Acs.Biochem.0C00348  0.482
2020 Zhao J, Du Z, Wang C, Mills KV. Methods to Study the Structure and Catalytic Activity of cis-Splicing Inteins. Methods in Molecular Biology (Clifton, N.J.). 2133: 55-73. PMID 32144663 DOI: 10.1007/978-1-0716-0434-2_4  0.579
2020 Yalala V, Chavez A, Lynch AK, Mills KV. Protein splicing and tryptophan fluorescence of salt‐dependent inteins from Haloquadratum walsbyi The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04643  0.439
2020 Tarrant SP, Jankowski BJ, Comeau HY, Wibben AC, Mills KV. Homing Endonuclease and Protein Splicing Activity of Inteins from Thermophilic Archaea The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03135  0.503
2020 Cawood A, Ruiz M, Mills K. Salt‐dependent protein splicing of an intein from the halophile Haloferax volcanii The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02647  0.561
2017 Ramsoomair CK, Yakely AE, Urbanski LM, Karanja K, Giaccone ZT, Siegart NM, Wang C, Gomez AV, Reitter JN, Mills KV. Coordination of the third step of protein splicing in two cyanobacterial inteins. Febs Letters. PMID 28649707 DOI: 10.1002/1873-3468.12730  0.552
2017 Zwarycz AS, Fossat MJ, Akanyeti O, Lin Z, Rosenman DJ, Garcia AE, Royer CA, Mills KV, Wang C. V67L Mutation Fills Internal Cavity to Stabilize RecA Mtu Intein. Biochemistry. PMID 28488863 DOI: 10.1021/Acs.Biochem.6B01264  0.322
2017 Minteer CJ, Siegart NM, Colelli KM, Liu X, Linhardt RJ, Wang C, Gomez AV, Reitter JN, Mills KV. Intein-promoted cyclization of aspartic acid flanking the intein leads to atypical N-terminal cleavage. Biochemistry. PMID 28165720 DOI: 10.1021/Acs.Biochem.6B00894  0.657
2016 Reitter JN, Cousin CE, Nicastri MC, Jaramillo MV, Mills KV. Salt-Dependent Conditional Protein Splicing of an Intein from Halobacterium salinarum. Biochemistry. PMID 26913597 DOI: 10.1021/Acs.Biochem.6B00128  0.539
2015 Mills K, Reitter J, Nicastri M, Colleli K, Williams J. Protein Splicing: Regulation by Temperature and Oxidation State of Non-Canonical Inteins Biophysical Journal. 108: 30a. DOI: 10.1016/J.Bpj.2014.11.188  0.487
2014 Mills KV, Johnson MA, Perler FB. Protein splicing: how inteins escape from precursor proteins. The Journal of Biological Chemistry. 289: 14498-505. PMID 24695729 DOI: 10.1074/Jbc.R113.540310  0.505
2014 Topilina NI, Mills KV. Recent advances in in vivo applications of intein-mediated protein splicing. Mobile Dna. 5: 5. PMID 24490831 DOI: 10.1186/1759-8753-5-5  0.541
2013 Nicastri MC, Xega K, Li L, Xie J, Wang C, Linhardt RJ, Reitter JN, Mills KV. Internal disulfide bond acts as a switch for intein activity. Biochemistry. 52: 5920-7. PMID 23906287 DOI: 10.1021/Bi400736C  0.551
2012 Chen W, Li L, Du Z, Liu J, Reitter JN, Mills KV, Linhardt RJ, Wang C. Intramolecular disulfide bond between catalytic cysteines in an intein precursor. Journal of the American Chemical Society. 134: 2500-3. PMID 22280304 DOI: 10.1021/Ja211010G  0.454
2011 Du Z, Liu J, Albracht CD, Hsu A, Chen W, Marieni MD, Colelli KM, Williams JE, Reitter JN, Mills KV, Wang C. Structural and mutational studies of a hyperthermophilic intein from DNA polymerase II of Pyrococcus abyssi. The Journal of Biological Chemistry. 286: 38638-48. PMID 21914805 DOI: 10.1074/Jbc.M111.290569  0.521
2011 Liu J, Du Z, Albracht CD, Naidu RO, Mills KV, Wang C. 1H, 13C, and 15N NMR assignments of the Pyrococcus abyssi DNA polymerase II intein. Biomolecular Nmr Assignments. 5: 233-5. PMID 21519863 DOI: 10.1007/S12104-011-9307-4  0.528
2011 Reitter JN, Mills KV. Canonical protein splicing of a class 1 intein that has a class 3 noncanonical sequence motif. Journal of Bacteriology. 193: 994-7. PMID 21131486 DOI: 10.1128/Jb.01287-10  0.408
2010 O'Brien KM, Schufreider AK, McGill MA, O'Brien KM, Reitter JN, Mills KV. Mechanism of protein splicing of the Pyrococcus abyssi lon protease intein. Biochemical and Biophysical Research Communications. 403: 457-61. PMID 21094142 DOI: 10.1016/J.Bbrc.2010.11.055  0.614
2009 Kerrigan AM, Powers TL, Dorval DM, Reitter JN, Mills KV. Protein splicing of the three Pyrococcus abyssi ribonucleotide reductase inteins. Biochemical and Biophysical Research Communications. 387: 153-7. PMID 19577540 DOI: 10.1016/J.Bbrc.2009.06.145  0.592
2007 Mills KV, Guilmette LW. Thermochemical analysis of neutralization reactions: An introductory discovery experiment Journal of Chemical Education. 84: 326-328. DOI: 10.1021/Ed084P326  0.302
2006 Mills KV, Connor KR, Dorval DM, Lewandowski KT. Protein purification via temperature-dependent, intein-mediated cleavage from an immobilized metal affinity resin. Analytical Biochemistry. 356: 86-93. PMID 16756933 DOI: 10.1016/J.Ab.2006.04.055  0.581
2005 Mills KV, Perler FB. The mechanism of intein-mediated protein splicing: variations on a theme. Protein and Peptide Letters. 12: 751-5. PMID 16305544 DOI: 10.2174/0929866054864337  0.582
2005 Mills KV, Dorval DM, Lewandowski KT. Kinetic analysis of the individual steps of protein splicing for the Pyrococcus abyssi PolII intein. The Journal of Biological Chemistry. 280: 2714-20. PMID 15557319 DOI: 10.1074/Jbc.M412313200  0.522
2004 Mills KV, Manning JS, Garcia AM, Wuerdeman LA. Protein splicing of a Pyrococcus abyssi intein with a C-terminal glutamine. The Journal of Biological Chemistry. 279: 20685-91. PMID 15024006 DOI: 10.1074/Jbc.M400887200  0.668
2001 Mills KV, Paulus H. Reversible inhibition of protein splicing by zinc ion. The Journal of Biological Chemistry. 276: 10832-8. PMID 11152694 DOI: 10.1074/Jbc.M011149200  0.668
1999 Lew BM, Mills KV, Paulus H. Characteristics of protein splicing in trans mediated by a semisynthetic split intein. Biopolymers. 51: 355-62. PMID 10685046 DOI: 10.1002/(Sici)1097-0282(1999)51:5<355::Aid-Bip5>3.0.Co;2-M  0.708
1998 Lew BM, Mills KV, Paulus H. Protein splicing in vitro with a semisynthetic two-component minimal intein. The Journal of Biological Chemistry. 273: 15887-90. PMID 9632632 DOI: 10.1074/Jbc.273.26.15887  0.699
1998 Mills KV, Lew BM, Jiang S, Paulus H. Protein splicing in trans by purified N- and C-terminal fragments of the Mycobacterium tuberculosis RecA intein. Proceedings of the National Academy of Sciences of the United States of America. 95: 3543-8. PMID 9520402 DOI: 10.1073/Pnas.95.7.3543  0.708
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