Dahlia R. Weiss - Publications

Affiliations: 
Heptares Therapeutics 
Area:
Computational Structural Biology

15/67 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Korczynska M, Clark MJ, Valant C, Xu J, Moo EV, Albold S, Weiss DR, Torosyan H, Huang W, Kruse AC, Lyda BR, May LT, Baltos JA, Sexton PM, Kobilka BK, et al. Structure-based discovery of selective positive allosteric modulators of antagonists for the Mmuscarinic acetylcholine receptor. Proceedings of the National Academy of Sciences of the United States of America. PMID 29453275 DOI: 10.1073/Pnas.1718037115  0.339
2016 Weiss DR, Bortolato A, Tehan B, Mason JS. GPCR-Bench: A Benchmarking Set and Practitioners' Guide for G Protein-Coupled Receptor Docking. Journal of Chemical Information and Modeling. PMID 26958710 DOI: 10.1021/Acs.Jcim.5B00660  0.333
2015 Harpsøe K, Isberg V, Tehan BG, Weiss D, Arsova A, Marshall FH, Bräuner-Osborne H, Gloriam DE. Selective Negative Allosteric Modulation Of Metabotropic Glutamate Receptors - A Structural Perspective of Ligands and Mutants. Scientific Reports. 5: 13869. PMID 26359761 DOI: 10.1038/Srep13869  0.335
2015 Bortolato A, Deflorian F, Weiss DR, Mason JS. Decoding the Role of Water Dynamics in Ligand-Protein Unbinding: CRF1R as a Test Case. Journal of Chemical Information and Modeling. 55: 1857-66. PMID 26335976 DOI: 10.1021/Acs.Jcim.5B00440  0.352
2015 Bennett KA, Doré AS, Christopher JA, Weiss DR, Marshall FH. Structures of mGluRs shed light on the challenges of drug development of allosteric modulators. Current Opinion in Pharmacology. 20: 1-7. PMID 25462286 DOI: 10.1016/J.Coph.2014.09.022  0.319
2014 Silva DA, Weiss DR, Pardo Avila F, Da LT, Levitt M, Wang D, Huang X. Millisecond dynamics of RNA polymerase II translocation at atomic resolution. Proceedings of the National Academy of Sciences of the United States of America. 111: 7665-70. PMID 24753580 DOI: 10.1073/Pnas.1315751111  0.483
2014 Coleman RG, Sterling T, Weiss DR. SAMPL4 & DOCK3.7: Lessons for automated docking procedures Journal of Computer-Aided Molecular Design. 28: 201-209. PMID 24515818 DOI: 10.1007/S10822-014-9722-6  0.307
2014 Weiss DR, Koehl P. Morphing methods to visualize coarse-grained protein dynamics Methods in Molecular Biology. 1084: 271-282. PMID 24061927 DOI: 10.1007/978-1-62703-658-0_15  0.312
2013 Kruse AC, Weiss DR, Rossi M, Hu J, Hu K, Eitel K, Gmeiner P, Wess J, Kobilka BK, Shoichet BK. Muscarinic receptors as model targets and antitargets for structure-based ligand discovery. Molecular Pharmacology. 84: 528-40. PMID 23887926 DOI: 10.1124/Mol.113.087551  0.327
2013 Weiss DR, Ahn S, Sassano MF, Kleist A, Zhu X, Strachan R, Roth BL, Lefkowitz RJ, Shoichet BK. Conformation guides molecular efficacy in docking screens of activated β-2 adrenergic G protein coupled receptor. Acs Chemical Biology. 8: 1018-26. PMID 23485065 DOI: 10.1021/Cb400103F  0.355
2012 Mysinger MM, Weiss DR, Ziarek JJ, Gravel S, Doak AK, Karpiak J, Heveker N, Shoichet BK, Volkman BF. Structure-based ligand discovery for the protein-protein interface of chemokine receptor CXCR4. Proceedings of the National Academy of Sciences of the United States of America. 109: 5517-22. PMID 22431600 DOI: 10.1073/Pnas.1120431109  0.378
2011 Bray JK, Weiss DR, Levitt M. Optimized torsion-angle normal modes reproduce conformational changes more accurately than cartesian modes. Biophysical Journal. 101: 2966-9. PMID 22208195 DOI: 10.1016/J.Bpj.2011.10.054  0.379
2010 Huang X, Wang D, Weiss DR, Bushnell DA, Kornberg RD, Levitt M. RNA polymerase II trigger loop residues stabilize and position the incoming nucleotide triphosphate in transcription. Proceedings of the National Academy of Sciences of the United States of America. 107: 15745-50. PMID 20798057 DOI: 10.1073/Pnas.1009898107  0.504
2009 Weiss DR, Levitt M. Can morphing methods predict intermediate structures? Journal of Molecular Biology. 385: 665-74. PMID 18996395 DOI: 10.1016/J.Jmb.2008.10.064  0.453
2008 Weiss DR, Raschke TM, Levitt M. How hydrophobic buckminsterfullerene affects surrounding water structure. The Journal of Physical Chemistry. B. 112: 2981-90. PMID 18275178 DOI: 10.1021/Jp076416H  0.389
Low-probability matches (unlikely to be authored by this person)
2018 Weiss DR, Karpiak J, Huang XP, Sassano MF, Lyu J, Roth BL, Shoichet BK. Selectivity Challenges in Docking Screens for GPCR Targets and Anti-Targets. Journal of Medicinal Chemistry. PMID 29990431 DOI: 10.1021/Acs.Jmedchem.8B00718  0.288
2023 Weiss DR, Bortolato A, Sun Y, Cai X, Lai C, Guo S, Shi L, Shanmugasundaram V. On Ternary Complex Stability in Protein Degradation: In Silico Molecular Glue Binding Affinity Calculations. Journal of Chemical Information and Modeling. PMID 37037192 DOI: 10.1021/acs.jcim.2c01386  0.242
2024 Szewczyk SM, Verma I, Edwards JT, Weiss DR, Chekler ELP. Trends in Neosubstrate Degradation by Cereblon-Based Molecular Glues and the Development of Novel Multiparameter Optimization Scores. Journal of Medicinal Chemistry. PMID 38170610 DOI: 10.1021/acs.jmedchem.3c01872  0.19
2024 Weiss DR, Baylon JL, Evans ED, Paiva A, Everlof G, Cutrone J, Broccatelli F. Balanced Permeability Index: A Multiparameter Index for Improved In Vitro Permeability. Acs Medicinal Chemistry Letters. 15: 457-462. PMID 38628792 DOI: 10.1021/acsmedchemlett.3c00542  0.12
2014 Nees S, Weiss DR, Juchem G, Partsch H. Critical role of the vasa venarum in the pathogenesis of chronic venous disease. Part ii: Therapeutic implications Phlebolymphology. 21: 112-124.  0.116
2019 Kelly A, Robbins DW, Tan M, Tenn-McClellan A, McIntosh J, Wu J, Konst Z, Kato D, Perez L, Tung J, Kolobova A, Ingallinera T, McKinnell J, Weiss D, Noviski M, et al. Targeted Protein Degradation of BTK As a Unique Therapeutic Approach for B Cell Malignancies Blood. 134: 3805-3805. DOI: 10.1182/blood-2019-129262  0.113
2024 Robbins DW, Noviski MA, Tan YS, Konst ZA, Kelly A, Auger P, Brathaban N, Cass R, Chan ML, Cherala G, Clifton MC, Gajewski S, Ingallinera TG, Karr D, Kato D, ... ... Weiss DR, et al. Discovery and Preclinical Pharmacology of NX-2127, an Orally Bioavailable Degrader of Bruton's Tyrosine Kinase with Immunomodulatory Activity for the Treatment of Patients with B Cell Malignancies. Journal of Medicinal Chemistry. PMID 38300987 DOI: 10.1021/acs.jmedchem.3c01007  0.104
2012 Nees S, Juchem G, Eberhorn N, Thallmair M, Förch S, Knott M, Senfti A, Fischlein T, Reichart B, Weiss DR. Wall structures of myocardial precapillary arterioles and postcapillary venules reexamined and reconstructed in vitro for studies on barrier functions American Journal of Physiology - Heart and Circulatory Physiology. 302: H51-H68. PMID 21984546 DOI: 10.1152/ajpheart.00358.2011  0.095
2012 Nees S, Juchem G, Weiss DR, Partsch H. Pathogenesis and therapy of chronic venous disease: New insights into structure and function of the leg venous system | Pathogenese und therapie der chronischen venenerkrankung: Neue erkenntnisse zu struktur und funktion der gefäßwand Phlebologie. 41: 246-257.  0.074
2008 Weiss DR, Thiel C, Strasser EF, Zimmermann R, Eckstein R. An optimized electrophoresis method for high-resolution imaging of von-Willebrand multimers. Thrombosis and Haemostasis. 100: 949-51. PMID 18989543 DOI: 10.1160/TH08-06-0403  0.07
2014 Weiss DR, Dankerl H, Martin A, Strasser EF, Ringwald J, Eckstein R, Zimmermann R. Von Willebrand factor multimer structure is neither acutely nor chronically affected by plateletpheresis. Clinical Laboratory. 60: 1207-12. PMID 25134391 DOI: 10.7754/Clin.Lab.2013.130807  0.066
2012 Weiss DR, Strasser EF, Ringwald J, Zimmermann R, Eckstein R. High resolution multimer analysis and the PFA-100 platelet function analyser can detect von Willebrand disease type 2A without a pathological ratio of ristocetin cofactor activity and von Willebrand antigen level Clinical Laboratory. 58: 1203-1209. PMID 23289190 DOI: 10.7754/Clin.Lab.2012.120112  0.062
2012 Juchem G, Weiss DR, Knott M, Senftl A, Förch S, Fischlein T, Kreuzer E, Reichart B, Laufer S, Nees S. Regulation of coronary venular barrier function by blood borne inflammatory mediators and pharmacological tools: Insights from novel microvascular wall models American Journal of Physiology - Heart and Circulatory Physiology. 302: H567-H581. PMID 22081707 DOI: 10.1152/Ajpheart.00360.2011  0.058
2014 Weiss DR, Franke D, Strasser EF, Ringwald J, Zimmermann R, Eckstein R. Von Willebrand factor, clotting factors, and clotting inhibitors in apheresis platelet concentrates Transfusion. 54: 633-639. PMID 23789907 DOI: 10.1111/trf.12304  0.054
2010 McCormick JJ, Li X, Weiss DR, Billiar KL, Wixted JJ. Biomechanical investigation of a novel ratcheting arthrodesis nail. Journal of Orthopaedic Surgery and Research. 5: 74. PMID 20942976 DOI: 10.1186/1749-799X-5-74  0.054
2012 Weiss DR, Eiche C, Hupke C, Schellerer VS, Keller AK, Strasser EF, Ringwald J, Zimmermann R, Eckstein R. The structure of the von Willebrand factor is not altered in patients with colorectal carcinoma. Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland. 14: 1500-6. PMID 22507880 DOI: 10.1111/j.1463-1318.2012.03049.x  0.051
2010 Juchem G, Weiss DR, Gansera B, Kemkes BM, Mueller-Hoecker J, Nees S. Pericytes in the macrovascular intima: possible physiological and pathogenetic impact. American Journal of Physiology. Heart and Circulatory Physiology. 298: H754-70. PMID 20023125 DOI: 10.1152/ajpheart.00343.2009  0.046
2013 Nees S, Weiss DR, Juchem G, Partsch H. Critical role of the vasa venarum in the pathogenesis of chronic venous disease. Part I: Malperfused venules as pathogenetic hot spots Phlebolymphology. 20: 193-201.  0.046
2014 Raczat T, Kraemer L, Gall C, Weiss DR, Eckstein R, Ringwald J. The influence of four different anticoagulants on dynamic light scattering of platelets Vox Sanguinis. 107: 196-199. PMID 24712311 DOI: 10.1111/vox.12150  0.045
1959 SHAPIRO HA, WEISS DR. Mitral insufficiency due to ruptured chordae tendineae simulating aortic stenosis. The New England Journal of Medicine. 261: 272-6. PMID 13674519 DOI: 10.1056/NEJM195908062610604  0.045
2014 Eckstein FM, Xiang W, Weiss DR, Zimmermann R, Strasser EF. The influence of pre-analytical conditions on platelet-derived microparticles. Clinical Laboratory. 60: 707-16. PMID 24839812 DOI: 10.7754/Clin.Lab.2013.130604  0.042
2015 Kraemer L, Raczat T, Weiss DR, Strobel J, Eckstein R, Ringwald J. Correlation of the hypotonic shock response and extent of shape change with the new ThromboLUX™ Vox Sanguinis. 109: 194-196. DOI: 10.1111/vox.12268  0.041
2015 Kraemer L, Raczat T, Weiss DR, Strobel J, Eckstein R, Ringwald J. Correlation of the hypotonic shock response and extent of shape change with the new ThromboLUX ™. Vox Sanguinis. 109: 194-6. PMID 25899969 DOI: 10.1111/vox.12268  0.041
2010 Weiss DR, Juchem G, Eblenkamp M, Kemkes BM, Gansera B, Geier M, Nees S. Search for optimized conditions for sealing and storage of bypass vessels: influence of preservation solution and filling pressure on the degree of endothelialization. International Journal of Clinical and Experimental Medicine. 3: 10-27. PMID 20369036  0.04
2013 Strasser EF, Happ S, Weiss DR, Pfeiffer A, Zimmermann R, Eckstein R. Microparticle detection in platelet products by three different methods Transfusion. 53: 156-166. PMID 22624624 DOI: 10.1111/j.1537-2995.2012.03720.x  0.04
2014 Breuer G, Weiss DR, Ringwald J. 'New' direct oral anticoagulants in the perioperative setting Current Opinion in Anaesthesiology. 27: 409-419. PMID 24979070 DOI: 10.1097/ACO.0000000000000100  0.04
2011 Weiss DR, Strasser EF, Zimmermann R, Eckstein R. High-resolution imaging of multimers can detect von Willebrand's disease type 2A even if ristocetin cofactor is higher than von Willebrand antigen. Haemophilia : the Official Journal of the World Federation of Hemophilia. 17: 325-6. PMID 21070489 DOI: 10.1111/j.1365-2516.2010.02407.x  0.039
2007 Weiss DR, O'Loughlin JL, Platt RW, Paradis G. Five-year predictors of physical activity decline among adults in low-income communities: a prospective study. The International Journal of Behavioral Nutrition and Physical Activity. 4: 2. PMID 17233904 DOI: 10.1186/1479-5868-4-2  0.039
2012 Weiss DR, Wolfson C, Yaffe MJ, Shrier I, Puts MT. Physician counseling of older adults about physical activity: the importance of context. American Journal of Health Promotion : Ajhp. 27: 71-4. PMID 23113775 DOI: 10.4278/ajhp.100804-QUAL-263  0.035
2012 Schellerer VS, Mueller-Bergh L, Merkel S, Zimmermann R, Weiss DR, Schildberg C, Hohenberger W, Croner RS. Is coagulation factor VIII a useful marker for colorectal carcinoma? The International Journal of Biological Markers. 27: 20-6. PMID 22139641 DOI: 10.5301/JBM.2011.8832  0.029
2011 Weiss DR, Fortenbacher S, Ringwald J, Strasser EF, Zimmermann R, Eckstein R. Transitory interruption of recommended storage conditions does not cause significant changes in in vitro parameters of leucocyte-depleted red blood cells. Vox Sanguinis. 100: 272-8. PMID 20860559 DOI: 10.1111/j.1423-0410.2010.01407.x  0.028
2007 Dupuis J, Weiss DR, Wolfson C. Gender and transportation access among community-dwelling seniors. Canadian Journal On Aging = La Revue Canadienne Du Vieillissement. 26: 149-58. PMID 17613446 DOI: 10.3138/cja.26.2.149  0.027
2003 Nees S, Weiss DR, Reichenbach-Klinke E, Rampp F, Heilmeier B, Kanbach J, Esperester A. Protective effects of flavonoids contained in the red vine leaf on venular endothelium against the attack of activated blood components in vitro. Arzneimittel-Forschung. 53: 330-41. PMID 12854360 DOI: 10.1055/s-0031-1297117  0.024
2003 Weiss DR, Glickman JF. Characterization of fatty acid synthase activity using scintillation proximity. Assay and Drug Development Technologies. 1: 161-6. PMID 15090142 DOI: 10.1089/154065803321537872  0.024
1975 Weiss DR, Cassady JR, Petersen R. Retinblastoma: a modification in radiation therapy technique. Radiology. 114: 705-8. PMID 804172 DOI: 10.1148/114.3.705  0.022
2010 Philippon MJ, Weiss DR, Kuppersmith DA, Briggs KK, Hay CJ. Arthroscopic labral repair and treatment of femoroacetabular impingement in professional hockey players. The American Journal of Sports Medicine. 38: 99-104. PMID 19966097 DOI: 10.1177/0363546509346393  0.019
2012 Nees S, Weiss DR, Senfti A, Knott M, Förch S, Schnurr M, Weyrich P, Juchem G. Isolation, bulk cultivation, and characterization of coronary microvascular pericytes: The second most frequent myocardial cell type in vitro American Journal of Physiology - Heart and Circulatory Physiology. 302: H69-H84. PMID 22037185 DOI: 10.1152/ajpheart.00359.2011  0.019
2011 Strasser EF, Weidinger T, Weiss DR, Strobel J, Zimmermann R, Eckstein R. Storage induced apoptosis of peripheral blood mononuclear cells obtained from leucoreduction system chambers Vox Sanguinis. 101: 106-111. PMID 21492183 DOI: 10.1111/j.1423-0410.2011.01473.x  0.017
2013 Zimmermann R, Krueger J, Filipović MR, Ivanović-Burmazovíc I, Calatzis A, Weiss DR, Eckstein R. A detailed examination of platelet function inhibition by nitric oxide in platelet-rich plasma and whole blood Clinical Laboratory. 59: 629-638. PMID 23865363 DOI: 10.7754/Clin.Lab.2012.120601  0.015
1976 Jaffrey IS, Lefkowitz L, Lestch SD, Weiss DR. Metastatic melanoma presenting as abnormal uterine bleeding: A case report. The Mount Sinai Journal of Medicine, New York. 43: 180-1. PMID 1082984  0.015
2010 Alvarez A, Kremer R, Weiss DR, Benedetti A, Haziza M, Trojan DA. Response of postpoliomyelitis patients to bisphosphonate treatment. Pm & R : the Journal of Injury, Function, and Rehabilitation. 2: 1094-103. PMID 21145521 DOI: 10.1016/J.Pmrj.2010.08.009  0.014
2008 Weiss DR, Wixted JJ, Anderson RC. Computer-aided surgery: assessing the accuracy of a navigation system. Orthopedics. 31: 247-50. PMID 18351044  0.012
1985 Rich TA, Weiss DR, Mies C, Fitzgerald TJ, Chaffey JT. Sphincter preservation in patients with low rectal cancer treated with radiation therapy with or without local excision or fulguration. Radiology. 156: 527-31. PMID 4011919 DOI: 10.1148/radiology.156.2.4011919  0.011
2013 Nees S, Weiss DR, Juchem G. Focus on cardiac pericytes Pflugers Archiv European Journal of Physiology. 465: 779-787. PMID 23443852 DOI: 10.1007/s00424-013-1240-1  0.011
2012 Zimmermann R, Weiss DR, Zingsem J, Ringwald J, Eckstein R. Pooled platelet concentrates and the quality of the red blood cell supply Clinical Laboratory. 58: 1-6. PMID 22372340  0.01
2011 Weiss DR, Goehring J, Weisbach V, Strasser EF, Ringwald J, Zimmermann R, Eckstein R. Centrifugation after irradiation of red blood cells does not accelerate haemolysis Clinical Laboratory. 57: 523-526. PMID 21888016  0.01
2011 Schellerer VS, Mueller-Bergh L, Merkel S, Zimmermann R, Weiss DR, Schlabrakowski A, Naschberger E, Stürzl M, Hohenberger W, Croner RS. The clinical value of von Willebrand factor in colorectal carcinomas American Journal of Translational Research. 3: 445-453.  0.01
2009 Weiss DR, Juchem G, Kemkes BM, Gansera B, Nees S. Extensive deendothelialization and thrombogenicity in routinely prepared vein grafts for coronary bypass operations: facts and remedy. International Journal of Clinical and Experimental Medicine. 2: 95-113. PMID 19684884  0.01
1986 Varner JL, Weiss DR, Rohrbaugh JW, Ellingson RJ. A study of attention as manifested by event-related desynchronization in the alpha band. Biomedical Sciences Instrumentation. 22: 61-4. PMID 3708079  0.01
1984 Boulton AJ, Angus E, Ayyar DR, Weiss DR. Diabetic thoracic polyradiculopathy presenting as abdominal swelling. British Medical Journal (Clinical Research Ed.). 289: 798-9. PMID 6434085  0.01
1976 Piro AJ, Weiss DR, Hellman S. Mediastinal Hodgkin's disease: a possible danger for intubation anesthesia. Intubation danger in Hodgkin's disease. International Journal of Radiation Oncology, Biology, Physics. 1: 415-9. PMID 972103  0.01
1971 Goldstein HB, Tsoukas E, Weiss DR. Smooth muscle hamartomas of the sigmoid colon: report of a case. American Journal of Clinical Pathology. 55: 377-9. PMID 5549906  0.01
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