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William W. Barrow - Publications

Affiliations: 
Oklahoma State University, Stillwater, OK, United States 
Area:
Veterinary Science Biology, Animal Physiology Biology, Microbiology Biology, Biochemistry
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22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Nammalwar B, Bourne CR, Wakeham N, Bourne PC, Barrow EW, Muddala NP, Bunce RA, Berlin KD, Barrow WW. Modified 2,4-diaminopyrimidine-based dihydrofolate reductase inhibitors as potential drug scaffolds against Bacillus anthracis. Bioorganic & Medicinal Chemistry. 23: 203-11. PMID 25435253 DOI: 10.1016/J.Bmc.2014.11.009  0.334
2014 Kobayashi M, Kinjo T, Koseki Y, Bourne CR, Barrow WW, Aoki S. Identification of novel potential antibiotics against Staphylococcus using structure-based drug screening targeting dihydrofolate reductase. Journal of Chemical Information and Modeling. 54: 1242-53. PMID 24655350 DOI: 10.1021/Ci400686D  0.336
2014 Nammalwar B, Muddala NP, Bourne CR, Henry M, Bourne PC, Bunce RA, Barrow EW, Berlin KD, Barrow WW. Synthesis and biological evaluation of 2,4-diaminopyrimidine-based antifolate drugs against Bacillus anthracis. Molecules (Basel, Switzerland). 19: 3231-46. PMID 24642909 DOI: 10.3390/Molecules19033231  0.365
2014 Bourne CR, Wakeham N, Webb N, Nammalwar B, Bunce RA, Berlin KD, Barrow WW. The structure and competitive substrate inhibition of dihydrofolate reductase from Enterococcus faecalis reveal restrictions to cofactor docking. Biochemistry. 53: 1228-38. PMID 24495113 DOI: 10.1021/Bi401104T  0.437
2013 Bourne CR, Wakeham N, Nammalwar B, Tseitin V, Bourne PC, Barrow EW, Mylvaganam S, Ramnarayan K, Bunce RA, Berlin KD, Barrow WW. Structure-activity relationship for enantiomers of potent inhibitors of B. anthracis dihydrofolate reductase. Biochimica Et Biophysica Acta. 1834: 46-52. PMID 22999981 DOI: 10.1016/J.Bbapap.2012.09.001  0.36
2012 Nammalwar B, Bourne CR, Bunce RA, Wakeham N, Bourne PC, Ramnarayan K, Mylvaganam S, Berlin KD, Barrow EW, Barrow WW. Inhibition of bacterial dihydrofolate reductase by 6-alkyl-2,4-diaminopyrimidines. Chemmedchem. 7: 1974-82. PMID 22930550 DOI: 10.1002/Cmdc.201200291  0.383
2012 Nammalwar B, Bunce RA, Berlin KD, Bourne CR, Bourne PC, Barrow EW, Barrow WW. Synthesis and biological activity of substituted 2,4-diaminopyrimidines that inhibit Bacillus anthracis. European Journal of Medicinal Chemistry. 54: 387-96. PMID 22703705 DOI: 10.1016/J.Ejmech.2012.05.018  0.348
2012 Barrow EW, Clinkenbeard PA, Duncan-Decocq RA, Perteet RF, Hill KD, Bourne PC, Valderas MW, Bourne CR, Clarkson NL, Clinkenbeard KD, Barrow WW. High-throughput screening of a diversity collection using biodefense category A and B priority pathogens. Journal of Biomolecular Screening. 17: 946-56. PMID 22653912 DOI: 10.1177/1087057112448216  0.303
2012 Nammalwar B, Bourne CR, Bunce RA, Wakeham N, Bourne PC, Ramnarayan K, Mylvaganam S, Berlin KD, Barrow EW, Barrow WW. Inside Cover: Inhibition of Bacterial Dihydrofolate Reductase by 6-Alkyl-2,4-diaminopyrimidines (ChemMedChem 11/2012) Chemmedchem. 7: 1866-1866. DOI: 10.1002/Cmdc.201290054  0.324
2010 Bourne CR, Barrow EW, Bunce RA, Bourne PC, Berlin KD, Barrow WW. Inhibition of antibiotic-resistant Staphylococcus aureus by the broad-spectrum dihydrofolate reductase inhibitor RAB1 Antimicrobial Agents and Chemotherapy. 54: 3825-3833. PMID 20606069 DOI: 10.1128/Aac.00361-10  0.398
2009 Bourne CR, Bunce RA, Bourne PC, Berlin KD, Barrow EW, Barrow WW. Crystal structure of Bacillus anthracis dihydrofolate reductase with the dihydrophthalazine-based trimethoprim derivative RAB1 provides a structural explanation of potency and selectivity. Antimicrobial Agents and Chemotherapy. 53: 3065-73. PMID 19364848 DOI: 10.1128/Aac.01666-08  0.421
2008 Valderas MW, Andi B, Barrow WW, Cook PF. Examination of intrinsic sulfonamide resistance in Bacillus anthracis: a novel assay for dihydropteroate synthase. Biochimica Et Biophysica Acta. 1780: 848-53. PMID 18342015 DOI: 10.1016/J.Bbagen.2008.02.003  0.411
2008 Valderas MW, Barrow WW. Establishment of a method for evaluating intracellular antibiotic efficacy in Brucella abortus-infected Mono Mac 6 monocytes. The Journal of Antimicrobial Chemotherapy. 61: 128-34. PMID 18024491 DOI: 10.1093/Jac/Dkm433  0.307
2007 Barrow EW, Dreier J, Reinelt S, Bourne PC, Barrow WW. In vitro efficacy of new antifolates against trimethoprim-resistant Bacillus anthracis. Antimicrobial Agents and Chemotherapy. 51: 4447-52. PMID 17875993 DOI: 10.1128/Aac.00628-07  0.364
2007 Böck RA, Soulages JL, Barrow WW. Substrate and inhibitor specificity of Mycobacterium avium dihydrofolate reductase. The Febs Journal. 274: 3286-98. PMID 17542991 DOI: 10.1111/J.1742-4658.2007.05855.X  0.502
2007 Valderas MW, Bourne PC, Barrow WW. Genetic basis for sulfonamide resistance in Bacillus anthracis. Microbial Drug Resistance (Larchmont, N.Y.). 13: 11-20. PMID 17536929 DOI: 10.1089/Mdr.2006.9992  0.324
2006 Barrow EW, Suling WJ, Seitz LE, Reynolds RC, Barrow WW. New antifolate inhibitors for Mycobacterium avium. Medicinal Chemistry (ShāRiqah (United Arab Emirates)). 2: 505-10. PMID 17017990 DOI: 10.2174/157340606778250225  0.376
2005 Suling WJ, Seitz LE, Reynolds RC, Barrow WW. New Mycobacterium avium antifolate shows synergistic effect when used in combination with dihydropteroate synthase inhibitors. Antimicrobial Agents and Chemotherapy. 49: 4801-3. PMID 16251337 DOI: 10.1128/Aac.49.11.4801-4803.2005  0.376
2004 Barrow EW, Bourne PC, Barrow WW. Functional cloning of Bacillus anthracis dihydrofolate reductase and confirmation of natural resistance to trimethoprim. Antimicrobial Agents and Chemotherapy. 48: 4643-9. PMID 15561838 DOI: 10.1128/Aac.48.12.4643-4649.2004  0.376
2004 Parker WB, Barrow EW, Allan PW, Shaddix SC, Long MC, Barrow WW, Bansal N, Maddry JA. Metabolism of 2-methyladenosine in Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland). 84: 327-36. PMID 15207808 DOI: 10.1016/J.Tube.2004.02.004  0.318
2003 Barrow EW, Westbrook L, Bansal N, Suling WJ, Maddry JA, Parker WB, Barrow WW. Antimycobacterial activity of 2-methyl-adenosine. The Journal of Antimicrobial Chemotherapy. 52: 801-8. PMID 14563890 DOI: 10.1093/Jac/Dkg444  0.342
1998 Suling WJ, Reynolds RC, Barrow EW, Wilson LN, Piper JR, Barrow WW. Susceptibilities of Mycobacterium tuberculosis and Mycobacterium avium complex to lipophilic deazapteridine derivatives, inhibitors of dihydrofolate reductase. Journal of Antimicrobial Chemotherapy. 42: 811-815. PMID 10052907 DOI: 10.1093/Jac/42.6.811  0.344
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