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Baskar Nammalwar, Ph.D. - Publications

Affiliations: 
2010 Chemistry Oklahoma State University, Stillwater, OK, United States 
Area:
Organic Chemistry
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49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Nammalwar B, Bunce RA. Recent Advances in Pyrimidine-Based Drugs. Pharmaceuticals (Basel, Switzerland). 17. PMID 38256937 DOI: 10.3390/ph17010104  0.481
2020 Muddala NP, White JC, Nammalwar B, Pratt I, Thomas LM, Bunce RA, Berlin KD, Bourne CR. Inhibitor design to target a unique feature in the folate pocket of Staphylococcus aureus dihydrofolate reductase. European Journal of Medicinal Chemistry. 200: 112412. PMID 32502861 DOI: 10.1016/J.Ejmech.2020.112412  0.555
2019 Punchi Hewage A, Yao H, Nammalwar B, Gnanasekaran KK, Lovell S, Bunce RA, Eshelman K, Phaniraj S, Lee M, Peterson BR, Battaile KP, Reitz AB, Rivera M. Small molecule inhibitors of the BfrB-Bfd interaction decrease Pseudomonas aeruginosa fitness and potentiate fluoroquinolone activity. Journal of the American Chemical Society. PMID 31038945 DOI: 10.2210/Pdb6Nli/Pdb  0.516
2019 Nammalwar B, Bunce RA, Berlin KD, Benbrook DM, Toal C. Synthesis and biological evaluation of SHetA2 (NSC-721689) analogs against the ovarian cancer cell line A2780. European Journal of Medicinal Chemistry. 170: 16-27. PMID 30878829 DOI: 10.1016/J.Ejmech.2019.03.010  0.587
2016 Muddala NP, Nammalwar B, Selvaraju S, Bunce RA. ChemInform Abstract: Diastereoselective Synthesis of N-Alkylated Octahydroacridines via a Catalyst-Free SNAr Approach. Cheminform. 47: no-no. DOI: 10.1002/CHIN.201607169  0.554
2015 Nammalwar B, Muddala NP, Pitchimani R, Bunce RA. OSU-6: A Highly Efficient, Metal-Free, Heterogeneous Catalyst for the Click Synthesis of 5-Benzyl and 5-Aryl-1H-tetrazoles. Molecules (Basel, Switzerland). 20: 22757-66. PMID 26703538 DOI: 10.3390/Molecules201219881  0.624
2015 Muddala NP, Nammalwar B, Selvaraju S, Bourne CR, Henry M, Bunce RA, Berlin KD, Barrow EW, Barrow WW. Evaluation of New Dihydrophthalazine-Appended 2,4-Diaminopyrimidines against Bacillus anthracis: Improved Syntheses Using a New Pincer Complex. Molecules (Basel, Switzerland). 20: 7222-44. PMID 25905602 DOI: 10.3390/Molecules20047222  0.622
2015 Gnanasekaran KK, Benbrook DM, Nammalwar B, Thavathiru E, Bunce RA, Berlin KD. Synthesis and evaluation of second generation Flex-Het scaffolds against the human ovarian cancer A2780 cell line. European Journal of Medicinal Chemistry. 96: 209-17. PMID 25880346 DOI: 10.1016/J.Ejmech.2015.03.070  0.575
2015 Nammalwar B, Bourne CR, Wakeham N, Bourne PC, Barrow EW, Muddala NP, Bunce RA, Berlin KD, Barrow WW. Modified 2,4-diaminopyrimidine-based dihydrofolate reductase inhibitors as potential drug scaffolds against Bacillus anthracis. Bioorganic & Medicinal Chemistry. 23: 203-11. PMID 25435253 DOI: 10.1016/J.Bmc.2014.11.009  0.589
2015 Muddala NP, Nammalwar B, Selvaraju S, Bourne CR, Henry M, Bunce RA, Berlin KD, Barrow EW, Barrow WW. Evaluation of new dihydrophthalazine-appended 2,4-diaminopyrimidines against Bacillus anthracis: Improved syntheses using a new pincer complex Molecules. 20: 7222-7244. DOI: 10.3390/molecules20047222  0.474
2015 Nammalwar B, Bunce RA, Hiett JT. Ring Size and Substitution Effects in the Tandem Reduction-Lactamization of ortho-Substituted Nitroarenes Organic Preparations and Procedures International. 47: 338-355. DOI: 10.1080/00304948.2015.1066643  0.587
2015 Muddala NP, Nammalwar B, Selvaraju S, Bunce RA. Diastereoselective Synthesis of N-Alkylated Octahydroacridines via a Catalyst-Free SNAr Approach Synthesis (Germany). 47: 3198-3206. DOI: 10.1055/S-0034-1381033  0.655
2015 Muddala NP, Nammalwar B, Bunce RA. Expeditious synthesis of (±)-diethyl 2-alkyl- and 2-aryl-(3-oxoisoindolin-1-yl)phosphonates catalysed by OSU-6 Rsc Advances. 5: 28389-28393. DOI: 10.1039/C5Ra02307F  0.61
2015 Nammalwar B, Muddala NP, Murie M, Bunce RA. Efficient syntheses of substituted (±)-3-oxoisoindoline-1-carbonitriles and carboxamides using OSU-6 Green Chemistry. 17: 2495-2503. DOI: 10.1039/C4Gc02486A  0.638
2015 Nammalwar B, Muddala NP, Watts FM, Bunce RA. Efficient conversion of acids and esters to amides and transamidation of primary amides using OSU-6 Tetrahedron. 71: 9101-9111. DOI: 10.1016/J.Tet.2015.10.016  0.589
2015 Muddala NP, Nammalwar B, Bunce RA. ChemInform Abstract: Expeditious Synthesis of (.+-.)-Diethyl 2-Alkyl- and 2-Aryl-(3-oxoisoindolin-1-yl)phosphonates Catalyzed by OSU-6. Cheminform. 46: no-no. DOI: 10.1002/CHIN.201533222  0.615
2014 Nammalwar B, Muddala NP, Bourne CR, Henry M, Bourne PC, Bunce RA, Barrow EW, Berlin KD, Barrow WW. Synthesis and biological evaluation of 2,4-diaminopyrimidine-based antifolate drugs against Bacillus anthracis. Molecules (Basel, Switzerland). 19: 3231-46. PMID 24642909 DOI: 10.3390/Molecules19033231  0.581
2014 Bourne CR, Wakeham N, Webb N, Nammalwar B, Bunce RA, Berlin KD, Barrow WW. The structure and competitive substrate inhibition of dihydrofolate reductase from Enterococcus faecalis reveal restrictions to cofactor docking. Biochemistry. 53: 1228-38. PMID 24495113 DOI: 10.1021/Bi401104T  0.552
2014 Benbrook DM, Nammalwar B, Long A, Matsumoto H, Singh A, Bunce RA, Berlin KD. SHetA2 interference with mortalin binding to p66shc and p53 identified using drug-conjugated magnetic microspheres. Investigational New Drugs. 32: 412-23. PMID 24254390 DOI: 10.1007/S10637-013-0041-X  0.512
2014 Gnanasekaran KK, Nammalwar B, Murie M, Bunce RA. Efficient synthesis of 1,3,4-oxadiazoles promoted by NH4Cl Tetrahedron Letters. 55: 6776-6778. DOI: 10.1016/J.Tetlet.2014.10.028  0.642
2014 Nammalwar B, Murie M, Fortenberry C, Bunce RA. Quinoline- and 1,8-naphthyridine-3-carboxylic acids using a self-catalyzed Friedländer approach Tetrahedron Letters. 55: 3181-3183. DOI: 10.1016/J.Tetlet.2014.04.010  0.624
2014 Nammalwar B, Fortenberry C, Bunce RA. Synthesis of α-aminonitriles under mild catalytic, metal-free conditions Tetrahedron Letters. 55: 379-381. DOI: 10.1016/J.Tetlet.2013.11.035  0.615
2014 Bunce RA, Nammalwar B, Gnanasekaran KK, Cain NR. Isoquinolin-1(2H)-ones and 1,6-naphthyridin-5(6H)-ones by an N-acylation-SNAr sequence Tetrahedron. 70: 838-844. DOI: 10.1016/J.Tet.2013.12.033  0.621
2014 Bunce RA, Nammalwar B, Gnanasekaran KK, Cain NR. ChemInform Abstract: Isoquinolin-1(2H)-ones and 1,6-Naphthyridin-5(6H)-ones by an N-Acylation-SNAr Sequence. Cheminform. 45: no-no. DOI: 10.1002/CHIN.201428149  0.525
2013 Nammalwar B, Bunce RA. Recent syntheses of 1,2,3,4-tetrahydroquinolines, 2,3-dihydro-4(1H)-quinolinones and 4(1H)-quinolinones using domino reactions. Molecules (Basel, Switzerland). 19: 204-32. PMID 24368602 DOI: 10.3390/Molecules19010204  0.644
2013 Nammalwar B, Bunce RA, Berlin KD, Bourne CR, Bourne PC, Barrow EW, Barrow WW. Comparative Study of the Frech Catalyst with Two Conventional Catalysts in the Heck Synthesis of 2,4-Diaminopyrimidine-based Antibiotics. Organic Preparations and Procedures International. 45: 66-71. PMID 23788820 DOI: 10.1080/00304948.2013.743755  0.628
2013 Bunce RA, Squires ST, Nammalwar B. 1-Alkyl- and (±)-1,2-dialkyl-2,3-dihydro-1,8-naphthyridin-4(1H)-ones by a tandem Michael-SNAr annulation reaction. The Journal of Organic Chemistry. 78: 2144-8. PMID 23113469 DOI: 10.1021/Jo3018632  0.621
2013 Bourne CR, Wakeham N, Nammalwar B, Tseitin V, Bourne PC, Barrow EW, Mylvaganam S, Ramnarayan K, Bunce RA, Berlin KD, Barrow WW. Structure-activity relationship for enantiomers of potent inhibitors of B. anthracis dihydrofolate reductase. Biochimica Et Biophysica Acta. 1834: 46-52. PMID 22999981 DOI: 10.1016/J.Bbapap.2012.09.001  0.523
2013 Fortenberry C, Nammalwar B, Bunce RA. Ammonium chloride-catalyzed synthesis of benzo-fused heterocycles from o-substituted anilines and orthoesters Organic Preparations and Procedures International. 45: 57-65. DOI: 10.1080/00304948.2013.743751  0.597
2013 Nammalwar B, Bunce RA. Friedel-Crafts cyclization of tertiary alcohols using bismuth(III) triflate Tetrahedron Letters. 54: 4330-4332. DOI: 10.1016/J.Tetlet.2013.06.026  0.56
2013 Nammalwar B, Fortenberry C, Bunce RA, Lageshetty SK, Ausman KD. Efficient oxidation of arylmethylene compounds using nano-MnO2 Tetrahedron Letters. 54: 2010-2013. DOI: 10.1016/J.Tetlet.2013.02.009  0.61
2012 Nammalwar B, Bunce RA, Berlin KD, Bourne CR, Bourne PC, Barrow EW, Barrow WW. Microwave-assisted Heck Synthesis of Substituted 2,4-Diaminopyrimidine-based Antibiotics. Organic Preparations and Procedures International. 44: 281-287. PMID 23805009 DOI: 10.1080/00304948.2012.676823  0.655
2012 Nammalwar B, Bunce RA, Berlin KD, Bourne CR, Bourne PC, Barrow EW, Barrow WW. Approaches to Iodinated Derivatives of Vanillin and Isovanillin. Organic Preparations and Procedures International. 44: 146-152. PMID 23805008 DOI: 10.1080/00304948.2012.643700  0.621
2012 Nammalwar B, Bourne CR, Bunce RA, Wakeham N, Bourne PC, Ramnarayan K, Mylvaganam S, Berlin KD, Barrow EW, Barrow WW. Inhibition of bacterial dihydrofolate reductase by 6-alkyl-2,4-diaminopyrimidines. Chemmedchem. 7: 1974-82. PMID 22930550 DOI: 10.1002/Cmdc.201200291  0.575
2012 Nammalwar B, Bunce RA, Berlin KD, Bourne CR, Bourne PC, Barrow EW, Barrow WW. Synthesis and biological activity of substituted 2,4-diaminopyrimidines that inhibit Bacillus anthracis. European Journal of Medicinal Chemistry. 54: 387-96. PMID 22703705 DOI: 10.1016/J.Ejmech.2012.05.018  0.626
2012 Bourne CR, Wakeham N, Bunce RA, Nammalwar B, Berlin KD, Barrow WW. Classifying compound mechanism of action for linking whole cell phenotypes to molecular targets. Journal of Molecular Recognition : Jmr. 25: 216-23. PMID 22434711 DOI: 10.1002/Jmr.2174  0.54
2012 Bunce RA, Harrison T, Nammalwar B. Efficient synthesis of selected phthalazine derivatives Heterocyclic Communications. 18: 123-126. DOI: 10.1515/Hc-2012-0079  0.625
2012 Bunce RA, Nammalwar B. Ethyl 1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylates by a tandem S NAr-addition-elimination reaction Journal of Heterocyclic Chemistry. 49: 658-663. DOI: 10.1002/Jhet.917  0.629
2012 Nammalwar B, Bourne CR, Bunce RA, Wakeham N, Bourne PC, Ramnarayan K, Mylvaganam S, Berlin KD, Barrow EW, Barrow WW. Inside Cover: Inhibition of Bacterial Dihydrofolate Reductase by 6-Alkyl-2,4-diaminopyrimidines (ChemMedChem 11/2012) Chemmedchem. 7: 1866-1866. DOI: 10.1002/Cmdc.201290054  0.539
2012 Bunce RA, Nammalwar B. ChemInform Abstract: Ethyl 1,4-Dihydro-4-oxo-1,8-naphthyridine-3-carboxylates by a Tandem SNAr-Addition-Elimination Reaction. Cheminform. 43: no-no. DOI: 10.1002/CHIN.201249164  0.582
2012 Bunce RA, Nammalwar B. ChemInform Abstract: New Conditions for Synthesis of (.+-.)-2-Monosubstituted and (.+-.)-2,2-Disubstituted 2,3-Dihydro-4(1H)-quinazolinones from 2-Nitro- and 2-Aminobenzamide. Cheminform. 43: no-no. DOI: 10.1002/CHIN.201207160  0.574
2011 Nammalwar B, Bunce RA, Benbrook DM, Lu T, Li HF, Chen YD, Berlin KD. Synthesis of N-[3,4-dihydro-4-(acetoxymethyl)-2,2,4-trimethyl-2H-1- benzothiopyran-6-yl]-N'-(4-nitrophenyl)thiourea and N-[3,4-dihydro-4- (hydroxymethyl)-2,2,4-trimethyl-2H-1-benzothiopyran-6-yl]-N'-(4-nitrophenyl) thiourea, a Major Metabolite of N-(3,4-dihydro-2,2,4,4-tetramethyl-2H-1- benzothiopyran-6-YL)-N'-(4-nitrophenyl)thiourea Phosphorus, Sulfur and Silicon and the Related Elements. 186: 189-204. DOI: 10.1080/10426507.2010.534521  0.566
2011 Bunce RA, Nammalwar B. New conditions for synthesis of (plusmn;)-2-monosubstituted and (plusmn;)-2,2-disubstituted 2,3-dihydro-4(1H)-quinazolinones from 2-nitro- and 2-aminobenzamide Journal of Heterocyclic Chemistry. 48: 991-997. DOI: 10.1002/Jhet.672  0.672
2011 Bunce RA, Nammalwar B. (±)-2-Aryl-2,3-dihydro-4(1H)-quinolinones by a tandem reduction-Michael addition reaction Journal of Heterocyclic Chemistry. 48: 613-619. DOI: 10.1002/Jhet.624  0.645
2011 Bunce RA, Nammalwar B. ChemInform Abstract: (.+-.)-2-Aryl-2,3-dihydro-4(1H)-quinolinones by a Tandem Reduction-Michael Addition Reaction. Cheminform. 42: no-no. DOI: 10.1002/CHIN.201142148  0.602
2011 Bunce RA, Nammalwar B. ChemInform Abstract: 4(1H)-Quinolinones by a Tandem Reduction-Addition-Elimination Reaction. Cheminform. 42: no-no. DOI: 10.1002/CHIN.201116149  0.584
2010 Bunce RA, Nammalwar B. 4(1H)-quinolinones by a tandem reduction-addition-elimination reaction Organic Preparations and Procedures International. 42: 557-563. DOI: 10.1080/00304948.2010.526512  0.615
2009 Bunce RA, Nammalwar B. 1, 2, 3, 9-tetrahydro-4H-carbazol-4-one and 8, 9-dihydropyrido- [1, 2-a]indol-6(7H)-one from 1H-indole-2-butanoic acid Journal of Heterocyclic Chemistry. 46: 172-177. DOI: 10.1002/Jhet.22  0.617
2009 Bunce RA, Nammalwar B, Slaughter LM. Divergent reactivity in tandem reduction - Michael ring closures of five- and six-membered cyclic enones Journal of Heterocyclic Chemistry. 46: 854-860. DOI: 10.1002/Jhet.111  0.577
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