Year |
Citation |
Score |
2018 |
Stauft CB, Shen SH, Song Y, Gorbatsevych O, Asare E, Futcher B, Mueller S, Payne A, Brecher M, Kramer L, Wimmer E. Extensive recoding of dengue virus type 2 specifically reduces replication in primate cells without gain-of-function in Aedes aegypti mosquitoes. Plos One. 13: e0198303. PMID 30192757 DOI: 10.1371/Journal.Pone.0198303 |
0.421 |
|
2017 |
Li Z, Sakamuru S, Huang R, Brecher M, Koetzner CA, Zhang J, Chen H, Qin CF, Zhang QY, Zhou J, Kramer LD, Xia M, Li H. Erythrosin B is a potent and broad-spectrum orthosteric inhibitor of the flavivirus NS2B-NS3 protease. Antiviral Research. PMID 29288700 DOI: 10.1016/J.Antiviral.2017.12.018 |
0.347 |
|
2017 |
Li Z, Brecher M, Deng YQ, Zhang J, Sakamuru S, Liu B, Huang R, Koetzner CA, Allen CA, Jones SA, Chen H, Zhang NN, Tian M, Gao F, Lin Q, et al. Existing drugs as broad-spectrum and potent inhibitors for Zika virus by targeting NS2B-NS3 interaction. Cell Research. PMID 28685770 DOI: 10.1038/Cr.2017.88 |
0.382 |
|
2017 |
Brecher M, Li Z, Liu B, Zhang J, Koetzner CA, Alifarag A, Jones SA, Lin Q, Kramer LD, Li H. A conformational switch high-throughput screening assay and allosteric inhibition of the flavivirus NS2B-NS3 protease. Plos Pathogens. 13: e1006411. PMID 28542603 DOI: 10.1371/Journal.Ppat.1006411 |
0.487 |
|
2017 |
Ciota AT, Bialosuknia SM, Zink SD, Brecher M, Ehrbar DJ, Morrissette MN, Kramer LD. Effects of Zika Virus Strain and Aedes Mosquito Species on Vector Competence. Emerging Infectious Diseases. 23. PMID 28430564 DOI: 10.3201/Eid2307.161633 |
0.409 |
|
2016 |
Nag DK, Brecher M, Kramer LD. DNA forms of arboviral RNA genomes are generated following infection in mosquito cell cultures. Virology. 498: 164-171. PMID 27588377 DOI: 10.1016/J.Virol.2016.08.022 |
0.348 |
|
2015 |
Brecher M, Chen H, Li Z, Banavali NK, Jones SA, Zhang J, Kramer LD, Li H. Identification and Characterization of Novel Broad-Spectrum Inhibitors of the Flavivirus Methyltransferase. Acs Infectious Diseases. 1: 340-349. PMID 26726314 DOI: 10.1021/Acsinfecdis.5B00070 |
0.404 |
|
2015 |
Brecher M, Chen H, Liu B, Banavali NK, Jones SA, Zhang J, Li Z, Kramer LD, Li H. Novel Broad Spectrum Inhibitors Targeting the Flavivirus Methyltransferase. Plos One. 10: e0130062. PMID 26098995 DOI: 10.1371/Journal.Pone.0130062 |
0.352 |
|
2015 |
LeMaster DM, Mustafi SM, Brecher M, Zhang J, Héroux A, Li H, Hernández G. Coupling of Conformational Transitions in the N-terminal Domain of the 51-kDa FK506-binding Protein (FKBP51) Near Its Site of Interaction with the Steroid Receptor Proteins. The Journal of Biological Chemistry. 290: 15746-57. PMID 25953903 DOI: 10.1074/Jbc.M115.650655 |
0.381 |
|
2015 |
Brecher MB, Li Z, Zhang J, Chen H, Lin Q, Liu B, Li H. Refolding of a fully functional flavivirus methyltransferase revealed that S-adenosyl methionine but not S-adenosyl homocysteine is copurified with flavivirus methyltransferase. Protein Science : a Publication of the Protein Society. 24: 117-28. PMID 25352331 DOI: 10.1002/Pro.2594 |
0.375 |
|
2014 |
Mustafi SM, Brecher M, Zhang J, Li H, Lemaster DM, Hernández G. Structural basis of conformational transitions in the active site and 80's loop in the FK506-binding protein FKBP12. The Biochemical Journal. 458: 525-36. PMID 24405377 DOI: 10.1042/Bj20131429 |
0.411 |
|
2013 |
Liu L, Chen H, Brecher MB, Li Z, Wei B, Nandi B, Zhang J, Ling H, Winslow G, Braun J, Li H. Pfit is a structurally novel Crohn's disease-associated superantigen. Plos Pathogens. 9: e1003837. PMID 24385909 DOI: 10.1371/Journal.Ppat.1003837 |
0.316 |
|
2013 |
Brecher M, Zhang J, Li H. The flavivirus protease as a target for drug discovery. Virologica Sinica. 28: 326-36. PMID 24242363 DOI: 10.1007/S12250-013-3390-X |
0.389 |
|
2013 |
Chen H, Zhou B, Brecher M, Banavali N, Jones SA, Li Z, Zhang J, Nag D, Kramer LD, Ghosh AK, Li H. S-adenosyl-homocysteine is a weakly bound inhibitor for a flaviviral methyltransferase. Plos One. 8: e76900. PMID 24130807 DOI: 10.1371/Journal.Pone.0076900 |
0.401 |
|
2012 |
Cardone G, Brecher M, Fontana J, Winkler DC, Butan C, White JM, Steven AC. Visualization of the two-step fusion process of the retrovirus avian sarcoma/leukosis virus by cryo-electron tomography. Journal of Virology. 86: 12129-37. PMID 22933285 DOI: 10.1128/Jvi.01880-12 |
0.641 |
|
2012 |
Brecher M, Schornberg KL, Delos SE, Fusco ML, Saphire EO, White JM. Cathepsin cleavage potentiates the Ebola virus glycoprotein to undergo a subsequent fusion-relevant conformational change. Journal of Virology. 86: 364-72. PMID 22031933 DOI: 10.1128/Jvi.05708-11 |
0.645 |
|
2009 |
Dube D, Brecher MB, Delos SE, Rose SC, Park EW, Schornberg KL, Kuhn JH, White JM. The primed ebolavirus glycoprotein (19-kilodalton GP1,2): sequence and residues critical for host cell binding. Journal of Virology. 83: 2883-91. PMID 19144707 DOI: 10.1128/Jvi.01956-08 |
0.609 |
|
2008 |
White JM, Delos SE, Brecher M, Schornberg K. Structures and mechanisms of viral membrane fusion proteins: multiple variations on a common theme. Critical Reviews in Biochemistry and Molecular Biology. 43: 189-219. PMID 18568847 DOI: 10.1080/10409230802058320 |
0.601 |
|
2008 |
Delos SE, Brecher MB, Chen Z, Melder DC, Federspiel MJ, White JM. Cysteines flanking the internal fusion peptide are required for the avian sarcoma/leukosis virus glycoprotein to mediate the lipid mixing stage of fusion with high efficiency. Journal of Virology. 82: 3131-4. PMID 18184714 DOI: 10.1128/Jvi.02266-07 |
0.609 |
|
2006 |
Harris A, Cardone G, Winkler DC, Heymann JB, Brecher M, White JM, Steven AC. Influenza virus pleiomorphy characterized by cryoelectron tomography. Proceedings of the National Academy of Sciences of the United States of America. 103: 19123-7. PMID 17146053 DOI: 10.1073/Pnas.0607614103 |
0.562 |
|
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