| Year |
Citation |
Score |
| 2019 |
Xu Y, Sromek AW, Neumeyer JL. Identification of fluorinated (R)-(-)-aporphine derivatives as potent and selective ligands at serotonin 5-HT receptor. Bioorganic & Medicinal Chemistry Letters. 29: 230-233. PMID 30545651 DOI: 10.1016/J.Bmcl.2018.11.050 |
0.333 |
|
| 2018 |
Subburaju S, Sromek AW, Seeman P, Neumeyer JL. New Dopamine D2 Receptor Agonist, [H]MCL-536, for Detecting Dopamine D2high Receptors in Vivo. Acs Chemical Neuroscience. PMID 29641175 DOI: 10.1021/Acschemneuro.8B00096 |
0.396 |
|
| 2016 |
Lincoln L, Fisher R, Jackson MJ, Jenner P, Neumeyer J, Sromek AW, Lees AJ, Rose S. Oral r-(-)-11-o-valeryl-n-n-propylnoraporphine reverses motor deficits in mptp-treated marmosets. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 27133947 DOI: 10.1002/Mds.26626 |
0.302 |
|
| 2014 |
Sromek AW, Zhang S, Akurathi V, Packard AB, Li W, Alagille D, Morley TJ, Baldwin R, Tamagnan G, Neumeyer JL. Convenient synthesis of 18F-radiolabeled R-(-)-N-n-propyl-2-(3-fluoropropanoxy-11-hydroxynoraporphine. Journal of Labelled Compounds & Radiopharmaceuticals. 57: 725-9. PMID 25400260 DOI: 10.1002/Jlcr.3246 |
0.398 |
|
| 2014 |
Sun JF, Wang YH, Chai JR, Li FY, Hang A, Lu G, Tao YM, Cheng Y, Chi ZQ, Neumeyer JL, Zhang A, Liu JG, Wang YJ. Pharmacological characterization and therapeutic potential for the treatment of opioid abuse with ATPM-ET, an N-ethyl substituted aminothiazolomorphinan with κ agonist and μ agonist/antagonist activity. European Journal of Pharmacology. 740: 455-63. PMID 24998879 DOI: 10.1016/j.ejphar.2014.06.045 |
0.338 |
|
| 2014 |
Finnema SJ, Stepanov V, Nakao R, Sromek AW, Zhang T, Neumeyer JL, George SR, Seeman P, Stabin MG, Jonsson C, Farde L, Halldin C. (18)F-MCL-524, an (18)F-Labeled Dopamine D2 and D3 Receptor Agonist Sensitive to Dopamine: A Preliminary PET Study. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 55: 1164-70. PMID 24790219 DOI: 10.2967/Jnumed.113.133876 |
0.386 |
|
| 2014 |
Sromek AW, Provencher BA, Russell S, Chartoff E, Knapp BI, Bidlack JM, Neumeyer JL. Preliminary pharmacological evaluation of enantiomeric morphinans. Acs Chemical Neuroscience. 5: 93-9. PMID 24393077 DOI: 10.1021/Cn400205Z |
0.365 |
|
| 2013 |
Provencher BA, Sromek AW, Li W, Russell S, Chartoff E, Knapp BI, Bidlack JM, Neumeyer JL. Synthesis and pharmacological evaluation of aminothiazolomorphinans at the mu and kappa opioid receptors. Journal of Medicinal Chemistry. 56: 8872-8. PMID 24107104 DOI: 10.1021/Jm401290Y |
0.367 |
|
| 2013 |
Ye N, Neumeyer JL, Baldessarini RJ, Zhen X, Zhang A. Update 1 of: Recent progress in development of dopamine receptor subtype-selective agents: potential therapeutics for neurological and psychiatric disorders. Chemical Reviews. 113: PR123-78. PMID 23464812 DOI: 10.1021/cr300113a |
0.327 |
|
| 2012 |
Neumeyer JL, Zhang B, Zhang T, Sromek AW, Knapp BI, Cohen DJ, Bidlack JM. Synthesis, binding affinity, and functional in vitro activity of 3-benzylaminomorphinan and 3-benzylaminomorphine ligands at opioid receptors. Journal of Medicinal Chemistry. 55: 3878-90. PMID 22439881 DOI: 10.1021/Jm3001086 |
0.352 |
|
| 2011 |
Sromek AW, Si YG, Zhang T, George SR, Seeman P, Neumeyer JL. Synthesis and Biological Evaluation of N-Fluoroalkyl and 2-Fluoroalkoxy Substituted Aporphines: Potential PET Ligands for Dopamine D(2) Receptors. Acs Medicinal Chemistry Letters. 2: 189-194. PMID 21666830 DOI: 10.1021/Ml1001689 |
0.408 |
|
| 2011 |
Zhang B, Zhang T, Sromek AW, Scrimale T, Bidlack JM, Neumeyer JL. Synthesis and binding affinity of novel mono- and bivalent morphinan ligands for κ, μ, and δ opioid receptors. Bioorganic & Medicinal Chemistry. 19: 2808-16. PMID 21482470 DOI: 10.1016/J.Bmc.2011.03.052 |
0.384 |
|
| 2011 |
Zhang T, Yan Z, Sromek A, Knapp BI, Scrimale T, Bidlack JM, Neumeyer JL. Aminothiazolomorphinans with mixed κ and μ opioid activity. Journal of Medicinal Chemistry. 54: 1903-13. PMID 21351746 DOI: 10.1021/Jm101542C |
0.415 |
|
| 2011 |
Balboni G, Salvadori S, Marczak ED, Knapp BI, Bidlack JM, Lazarus LH, Peng X, Si YG, Neumeyer JL. Opioid bifunctional ligands from morphine and the opioid pharmacophore Dmt-Tic. European Journal of Medicinal Chemistry. 46: 799-803. PMID 21216504 DOI: 10.1016/j.ejmech.2010.12.001 |
0.328 |
|
| 2010 |
Balboni G, Salvadori S, Trapella C, Knapp BI, Bidlack JM, Lazarus LH, Peng X, Neumeyer JL. Evolution of the Bifunctional Lead μ Agonist / δ Antagonist Containing the Dmt-Tic Opioid Pharmacophore. Acs Chemical Neuroscience. 1: 155-164. PMID 20352071 DOI: 10.1021/cn900025j |
0.382 |
|
| 2010 |
Fulton BS, Knapp BL, Bidlack JM, Neumeyer JL. Effect of linker substitution on the binding of butorphan univalent and bivalent ligands to opioid receptors. Bioorganic & Medicinal Chemistry Letters. 20: 1507-9. PMID 20144870 DOI: 10.1016/j.bmcl.2010.01.101 |
0.345 |
|
| 2010 |
Decker M, Si YG, Knapp BI, Bidlack JM, Neumeyer JL. Synthesis and opioid receptor binding affinities of 2-substituted and 3-aminomorphinans: ligands for mu, kappa, and delta opioid receptors. Journal of Medicinal Chemistry. 53: 402-18. PMID 19928862 DOI: 10.1021/jm9013482 |
0.382 |
|
| 2010 |
MORIN I, GAO Y, KULA NS, BALDESSARINI RJ, NEUMEYER JL. ChemInform Abstract: N-Monofluoroalkylnoraporphines: Synthesis and Binding Dopamine Receptor Studies. Cheminform. 24: no-no. DOI: 10.1002/CHIN.199320221 |
0.339 |
|
| 2010 |
NEUMEYER JL, GAO Y, KULA NS, BALDESSARINI RJ. ChemInform Abstract: R- and S-Enantiomers of 11-Hydroxy- (Ia) and 10,11-Dihydroxy-N- allylnoraporphine (Ib): Synthesis and Affinity for Dopamine Receptors in Rat Brain Tissue. Cheminform. 22: no-no. DOI: 10.1002/CHIN.199122253 |
0.307 |
|
| 2010 |
Booth RG, Neumeyer JL, Baldessarini RJ. Therapeutic and Diagnostic Agents for Parkinson’s Disease Burger's Medicinal Chemistry and Drug Discovery. 529-568. DOI: 10.1002/0471266949.Bmc105.Pub2 |
0.367 |
|
| 2009 |
Decker M, Fulton BS, Zhang B, Knapp BI, Bidlack JM, Neumeyer JL. Univalent and bivalent ligands of butorphan: characteristics of the linking chain determine the affinity and potency of such opioid ligands. Journal of Medicinal Chemistry. 52: 7389-96. PMID 19634902 DOI: 10.1021/jm900379p |
0.368 |
|
| 2009 |
Chen XQ, Zhang J, Neumeyer JL, Jin GZ, Hu GY, Zhang A, Zhen X. Arylbenzazepines are potent modulators for the delayed rectifier K+ channel: a potential mechanism for their neuroprotective effects. Plos One. 4: e5811. PMID 19503734 DOI: 10.1371/Journal.Pone.0005811 |
0.302 |
|
| 2009 |
Wang YJ, Tao YM, Li FY, Wang YH, Xu XJ, Chen J, Cao YL, Chi ZQ, Neumeyer JL, Zhang A, Liu JG. Pharmacological characterization of ATPM [(-)-3-aminothiazolo[5,4-b]-N-cyclopropylmethylmorphinan hydrochloride], a novel mixed kappa-agonist and mu-agonist/-antagonist that attenuates morphine antinociceptive tolerance and heroin self-administration behavior. The Journal of Pharmacology and Experimental Therapeutics. 329: 306-13. PMID 19136637 DOI: 10.1124/jpet.108.142802 |
0.365 |
|
| 2009 |
Si YG, Choi YK, Gardner MP, Tarazi FI, Baldessarini RJ, Neumeyer JL. Synthesis and neuropharmacological evaluation of esters of R(-)-N-alkyl-11-hydroxy-2-methoxynoraporphines. Bioorganic & Medicinal Chemistry Letters. 19: 51-3. PMID 19058967 DOI: 10.1016/J.Bmcl.2008.11.025 |
0.441 |
|
| 2008 |
Fulton BS, Knapp BI, Bidlack JM, Neumeyer JL. Synthesis and pharmacological evaluation of hydrophobic esters and ethers of butorphanol at opioid receptors. Bioorganic & Medicinal Chemistry Letters. 18: 4474-6. PMID 18674902 DOI: 10.1016/j.bmcl.2008.07.054 |
0.389 |
|
| 2008 |
Si YG, Gardner MP, Tarazi FI, Baldessarini RJ, Neumeyer JL. Synthesis and binding studies of 2-O- and 11-O-substituted N-alkylnoraporphines. Bioorganic & Medicinal Chemistry Letters. 18: 3971-3. PMID 18585036 DOI: 10.1016/J.Bmcl.2008.06.016 |
0.41 |
|
| 2008 |
Mathews JL, Fulton BS, Negus SS, Neumeyer JL, Bidlack JM. In vivo characterization of (-)(-)MCL-144 and (+)(-)MCL-193: isomeric, bivalent ligands with mu/kappa agonist properties. Neurochemical Research. 33: 2142-50. PMID 18528756 DOI: 10.1007/s11064-008-9752-3 |
0.386 |
|
| 2008 |
Si YG, Gardner MP, Tarazi FI, Baldessarini RJ, Neumeyer JL. Synthesis and dopamine receptor affinities of N-alkyl-11-hydroxy-2-methoxynoraporphines: N-alkyl substituents determine D1 versus D2 receptor selectivity. Journal of Medicinal Chemistry. 51: 983-7. PMID 18251489 DOI: 10.1021/Jm701045J |
0.408 |
|
| 2008 |
Reindl JD, Rowan K, Carey AN, Peng X, Neumeyer JL, McLaughlin JP. Antidepressant-like effects of the novel kappa opioid antagonist MCL-144B in the forced-swim test. Pharmacology. 81: 229-35. PMID 18176093 DOI: 10.1159/000112867 |
0.313 |
|
| 2008 |
Csutorás C, Berényi S, Neumeyer JL. Microwave-promoted acid-catalyzed rearrangement of morphinans - A high-yield synthesis of R(-)-apomorphine Synthetic Communications. 38: 866-872. DOI: 10.1080/00397910701845357 |
0.345 |
|
| 2007 |
Desai RI, Neumeyer JL, Bergman J, Paronis CA. Pharmacological characterization of the effects of dopamine D(1) agonists on eye blinking in rats. Behavioural Pharmacology. 18: 745-54. PMID 17989512 DOI: 10.1097/Fbp.0B013E3282F14Ee6 |
0.352 |
|
| 2007 |
Si YG, Gardner MP, Tarazi FI, Baldessarini RJ, Neumeyer JL. R-(-)-N-alkyl-11-hydroxy-10-hydroxymethyl- and 10-methyl-aporphines as 5-HT1A receptor ligands. Bioorganic & Medicinal Chemistry Letters. 17: 4128-30. PMID 17543523 DOI: 10.1016/J.Bmcl.2007.05.057 |
0.396 |
|
| 2007 |
Zhang A, Li F, Ding C, Yao Q, Knapp BI, Bidlack JM, Neumeyer JL. Synthesis and pharmacological evaluation of 6,7-indolo/thiazolo-morphinans--further SAR of levorphanol. Journal of Medicinal Chemistry. 50: 2747-51. PMID 17488103 DOI: 10.1021/jm0701674 |
0.386 |
|
| 2007 |
Wuest F, Berndt M, Strobel K, van den Hoff J, Peng X, Neumeyer JL, Bergmann R. Synthesis and radiopharmacological characterization of 2beta-carbo-2'-[18F]fluoroethoxy-3beta-(4-bromo-phenyl)tropane ([18F]MCL-322) as a PET radiotracer for imaging the dopamine transporter (DAT). Bioorganic & Medicinal Chemistry. 15: 4511-9. PMID 17467995 DOI: 10.1016/j.bmc.2007.04.019 |
0.301 |
|
| 2007 |
Peng X, Knapp BI, Bidlack JM, Neumeyer JL. In-vitro investigation of oxazol and urea analogues of morphinan at opioid receptors. Bioorganic & Medicinal Chemistry. 15: 4106-12. PMID 17433695 DOI: 10.1016/j.bmc.2007.03.076 |
0.377 |
|
| 2007 |
Peng X, Knapp BI, Bidlack JM, Neumeyer JL. Pharmacological properties of bivalent ligands containing butorphan linked to nalbuphine, naltrexone, and naloxone at mu, delta, and kappa opioid receptors. Journal of Medicinal Chemistry. 50: 2254-8. PMID 17407276 DOI: 10.1021/jm061327z |
0.336 |
|
| 2007 |
Peng X, Neumeyer JL. Kappa receptor bivalent ligands. Current Topics in Medicinal Chemistry. 7: 363-73. PMID 17305578 DOI: 10.2174/156802607779941251 |
0.348 |
|
| 2007 |
Peng X, Knapp BI, Bidlack JM, Neumeyer JL. High-affinity carbamate analogues of morphinan at opioid receptors. Bioorganic & Medicinal Chemistry Letters. 17: 1508-11. PMID 17276685 DOI: 10.1016/j.bmcl.2007.01.013 |
0.398 |
|
| 2007 |
Desai RI, Neumeyer JL, Paronis CA, Nguyen P, Bergman J. Behavioral effects of the R-(+)- and S-(-)-enantiomers of the dopamine D(1)-like partial receptor agonist SKF 83959 in monkeys. European Journal of Pharmacology. 558: 98-106. PMID 17207791 DOI: 10.1016/J.Ejphar.2006.11.042 |
0.379 |
|
| 2007 |
Desai RI, Neumeyer JL, Paronis CA, Nguyen P, Bergman J. Erratum to: Behavioral effects of the R-(+)- and S-(−)-enantiomers of the dopamine D1-like partial receptor agonist SKF 83959 in monkeys [European Journal of Pharmacology 558 (2007) 98106] European Journal of Pharmacology. 575: 187. DOI: 10.1016/J.Ejphar.2007.08.013 |
0.398 |
|
| 2007 |
Peng X, Knapp BI, Bidlack JM, Neumeyer JL. High Affinity of Carbamate Analogues of Morphinan atOpioid Receptors Bioorganic & Medicinal Chemistry Letters. 17: 1508. DOI: 10.1016/J.Bmcl.2007.01.03 |
0.404 |
|
| 2006 |
Neumeyer JL, Peng X, Knapp BI, Bidlack JM, Lazarus LH, Salvadori S, Trapella C, Balboni G. New opioid designed multiple ligand from Dmt-Tic and morphinan pharmacophores. Journal of Medicinal Chemistry. 49: 5640-3. PMID 16942040 DOI: 10.1021/jm0605785 |
0.319 |
|
| 2006 |
Peng X, Knapp BI, Bidlack JM, Neumeyer JL. Synthesis and preliminary in vitro investigation of bivalent ligands containing homo- and heterodimeric pharmacophores at mu, delta, and kappa opioid receptors. Journal of Medicinal Chemistry. 49: 256-62. PMID 16392810 DOI: 10.1021/jm050577x |
0.372 |
|
| 2006 |
Tóth M, Berényi S, Csutorás C, Kula NS, Zhang K, Baldessarini RJ, Neumeyer JL. Synthesis and dopamine receptor binding of sulfur-containing aporphines. Bioorganic & Medicinal Chemistry. 14: 1918-23. PMID 16290940 DOI: 10.1016/j.bmc.2005.10.049 |
0.393 |
|
| 2005 |
Mathews JL, Peng X, Xiong W, Zhang A, Negus SS, Neumeyer JL, Bidlack JM. Characterization of a novel bivalent morphinan possessing kappa agonist and micro agonist/antagonist properties. The Journal of Pharmacology and Experimental Therapeutics. 315: 821-7. PMID 16076937 DOI: 10.1124/jpet.105.084343 |
0.381 |
|
| 2005 |
Zhang A, Csutoras C, Zong R, Neumeyer JL. Synthesis of 2-fluoro-11-hydroxy-N-propylnoraporphine: a potential dopamine D2 agonist. Organic Letters. 7: 3239-42. PMID 16018630 DOI: 10.1021/ol051010d |
0.445 |
|
| 2005 |
Finnema SJ, Seneca N, Farde L, Shchukin E, Sóvágó J, Gulyás B, Wikström HV, Innis RB, Neumeyer JL, Halldin C. A preliminary PET evaluation of the new dopamine D2 receptor agonist [11C]MNPA in cynomolgus monkey. Nuclear Medicine and Biology. 32: 353-60. PMID 15878504 DOI: 10.1016/J.Nucmedbio.2005.01.007 |
0.423 |
|
| 2004 |
Peng X, Zhang A, Kula NS, Baldessarini RJ, Neumeyer JL. Synthesis and amine transporter affinities of novel phenyltropane derivatives as potential positron emission tomography (PET) imaging agents. Bioorganic & Medicinal Chemistry Letters. 14: 5635-9. PMID 15482938 DOI: 10.1016/j.bmcl.2004.08.049 |
0.352 |
|
| 2004 |
Csutoras C, Zhang A, Zhang K, Kula NS, Baldessarini RJ, Neumeyer JL. Synthesis and neuropharmacological evaluation of R(-)-N-alkyl-11-hydroxynoraporphines and their esters. Bioorganic & Medicinal Chemistry. 12: 3553-9. PMID 15186839 DOI: 10.1016/j.bmc.2004.04.029 |
0.409 |
|
| 2004 |
Csutoras C, Zhang A, Bidlack JM, Neumeyer JL. An investigation of the N-demethylation of 3-deoxymorphine and the affinity of the alkylation products to mu, delta, and kappa receptors. Bioorganic & Medicinal Chemistry. 12: 2687-90. PMID 15110850 DOI: 10.1016/j.bmc.2004.03.011 |
0.406 |
|
| 2004 |
Zhang A, Xiong W, Hilbert JE, DeVita EK, Bidlack JM, Neumeyer JL. 2-aminothiazole-derived opioids. Bioisosteric replacement of phenols. Journal of Medicinal Chemistry. 47: 1886-8. PMID 15055988 DOI: 10.1021/jm049978n |
0.362 |
|
| 2004 |
Chaly T, Baldwin RM, Neumeyer JL, Hellman MJ, Dhawan V, Garg PK, Tamagnan G, Staley JK, Al-Tikriti MS, Hou Y, Zoghbi SS, Gu XH, Zong R, Eidelberg D. Radiosynthesis of [18F] N-(3-Fluoropropyl)-2-beta-Carbomethoxy-3-beta-(4-Bromophenyl) Nortropane and the regional brain uptake in non human primate using PET. Nuclear Medicine and Biology. 31: 125-31. PMID 14741577 DOI: 10.1016/S0969-8051(03)00110-0 |
0.316 |
|
| 2004 |
Zhang A, Xiong W, Bidlack JM, Hilbert JE, Knapp BI, Wentland MP, Neumeyer JL. 10-Ketomorphinan and 3-substituted-3-desoxymorphinan analogues as mixed kappa and micro opioid ligands: synthesis and biological evaluation of their binding affinity at opioid receptors. Journal of Medicinal Chemistry. 47: 165-74. PMID 14695830 DOI: 10.1021/Jm0304156 |
0.419 |
|
| 2003 |
Neumeyer JL, Zhang A, Xiong W, Gu XH, Hilbert JE, Knapp BI, Negus SS, Mello NK, Bidlack JM. Design and synthesis of novel dimeric morphinan ligands for kappa and micro opioid receptors. Journal of Medicinal Chemistry. 46: 5162-70. PMID 14613319 DOI: 10.1021/Jm030139V |
0.373 |
|
| 2003 |
Neumeyer JL, Kula NS, Bergman J, Baldessarini RJ. Receptor affinities of dopamine D1 receptor-selective novel phenylbenzazepines. European Journal of Pharmacology. 474: 137-40. PMID 12921854 DOI: 10.1016/S0014-2999(03)02008-9 |
0.435 |
|
| 2003 |
Zhang A, Van Vliet S, Neumeyer JL. Synthesis of aminothiazole derived morphinans Tetrahedron Letters. 44: 6459-6462. DOI: 10.1016/S0040-4039(03)01560-0 |
0.324 |
|
| 2002 |
Zhang K, Baldessarini RJ, Tarazi FI, Neumeyer JL. Selective Dopamine D4 Receptor Antagonists: Review ofStructure-Activity Relationships Current Medicinal Chemistry - Central Nervous System Agents. 2: 259-274. DOI: 10.2174/1568015023357914 |
0.399 |
|
| 2001 |
Gu XH, Zong R, Kula NS, Baldessarini RJ, Neumeyer JL. Synthesis and biological evaluation of a series of novel N- or O-fluoroalkyl derivatives of tropane: potential positron emission tomography (PET) imaging agents for the dopamine transporter. Bioorganic & Medicinal Chemistry Letters. 11: 3049-53. PMID 11714608 DOI: 10.1016/S0960-894X(01)00626-6 |
0.356 |
|
| 2001 |
Neumeyer JL, Gu XH, van Vliet LA, DeNunzio NJ, Rusovici DE, Cohen DJ, Negus SS, Mello NK, Bidlack JM. Mixed kappa agonists and mu agonists/antagonists as potential pharmacotherapeutics for cocaine abuse: synthesis and opioid receptor binding affinity of N-substituted derivatives of morphinan. Bioorganic & Medicinal Chemistry Letters. 11: 2735-40. PMID 11591513 DOI: 10.1016/S0960-894X(01)00543-1 |
0.406 |
|
| 2000 |
Neumeyer JL, Mello NK, Negus SS, Bidlack JM. Kappa opioid agonists as targets for pharmacotherapies in cocaine abuse. Pharmaceutica Acta Helvetiae. 74: 337-44. PMID 10812979 DOI: 10.1016/S0031-6865(99)00044-8 |
0.363 |
|
| 2000 |
Scanley BE, Gandelman MS, Laruelle M, Al-Tikriti MS, Baldwin RM, Zoghbi SS, Hoffer PB, Wang S, Neumeyer JL, Innis RB. [123I]IPCIT and [123I]beta-CIT as SPECT tracers for the dopamine transporter: a comparative analysis in nonhuman primates. Nuclear Medicine and Biology. 27: 13-21. PMID 10755641 DOI: 10.1016/S0969-8051(99)00083-9 |
0.303 |
|
| 2000 |
Neumeyer JL, Bidlack JM, Zong R, Bakthavachalam V, Gao P, Cohen DJ, Negus SS, Mello NK. Synthesis and opioid receptor affinity of morphinan and benzomorphan derivatives: mixed kappa agonists and mu agonists/antagonists as potential pharmacotherapeutics for cocaine dependence. Journal of Medicinal Chemistry. 43: 114-22. PMID 10633042 DOI: 10.1021/Jm9903343 |
0.378 |
|
| 1999 |
Kula NS, Baldessarini RJ, Tarazi FI, Fisser R, Wang S, Trometer J, Neumeyer JL. [3H]beta-CIT: a radioligand for dopamine transporters in rat brain tissue. European Journal of Pharmacology. 385: 291-4. PMID 10607889 DOI: 10.1016/S0014-2999(99)00695-0 |
0.308 |
|
| 1999 |
Zhang K, Tarazi FI, Kula NS, Baldessarini RJ, Neumeyer JL. Selective alkylatation of dopamine D2 and D4 receptors in rat brain by N-(p-isothiocyanatophenethyl)spiperone. Neuroscience Letters. 274: 155-8. PMID 10548413 DOI: 10.1016/S0304-3940(99)00700-4 |
0.406 |
|
| 1998 |
Tarazi FI, Yeghiayan SK, Neumeyer JL, Baldessarini RJ. Medial prefrontal cortical D2 and striatolimbic D4 dopamine receptors: common targets for typical and atypical antipsychotic drugs. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 22: 693-707. PMID 9682281 DOI: 10.1016/S0278-5846(98)00033-5 |
0.381 |
|
| 1998 |
Yeghiayan SK, Gongwer MA, Baldessarini RJ, Kula NS, Zong R, Neumeyer JL. Local injection of alkylating and nonalkylating dopamine receptor antagonists into rat basal forebrain: autoradiographic assessment of D2-like and D3 sites. Brain Research. 792: 324-6. PMID 9593972 DOI: 10.1016/S0006-8993(98)00202-9 |
0.406 |
|
| 1997 |
Tarazi FI, Yeghiayan SK, Baldessarini RJ, Kula NS, Neumeyer JL. Long-term effects of S(+)N-n-propylnorapomorphine compared with typical and atypical antipsychotics: differential increases of cerebrocortical D2-like and striatolimbic D4-like dopamine receptors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 17: 186-96. PMID 9272485 DOI: 10.1016/S0893-133X(97)00046-8 |
0.4 |
|
| 1997 |
Tamagnan G, Neumeyer JL, Gao Y, Wang S, Kula NS, Baldessarini RJ. N-Phthalimidoalkyl derivatives of 2β-carbomethoxy-3β-(4'-iodophenyl)tropane (β-CIT): Brain monoamine transporter affinity Bioorganic and Medicinal Chemistry Letters. 7: 337-340. DOI: 10.1016/S0960-894X(97)00009-7 |
0.344 |
|
| 1997 |
Tarazi FI, Yeghiayan SK, Baldessarini RJ, Neumeyer JL. S(+)-N-n-propylnorapomorphine ([+]-NPA): A novel atypical antipsy chotic with clozapine-like effects Schizophrenia Research. 24: 82. DOI: 10.1016/S0920-9964(97)82223-2 |
0.331 |
|
| 1996 |
Mak CK, Avalos M, Randall PK, Kwan SW, Abell CW, Neumeyer JL, Whisennand R, Wilcox RE. Improved models for pharmacological null experiments: calculation of drug efficacy at recombinant D1A dopamine receptors stably expressed in clonal cell lines. Neuropharmacology. 35: 549-70. PMID 8887963 DOI: 10.1016/0028-3908(96)84625-9 |
0.374 |
|
| 1996 |
Neumeyer JL, Tamagnan G, Wang S, Gao Y, Milius RA, Kula NS, Baldessarini RJ. N-substituted analogs of 2 beta-carbomethoxy-3 beta- (4'-iodophenyl)tropane (beta-CIT) with selective affinity to dopamine or serotonin transporters in rat forebrain. Journal of Medicinal Chemistry. 39: 543-8. PMID 8558525 DOI: 10.1021/jm9505324 |
0.309 |
|
| 1995 |
Lundkvist C, Halldin C, Swahn CG, Hall H, Karlsson P, Nakashima Y, Wang S, Milius RA, Neumeyer JL, Farde L. [O-methyl-11C]beta-CIT-FP, a potential radioligand for quantitation of the dopamine transporter: preparation, autoradiography, metabolite studies, and positron emission tomography examinations. Nuclear Medicine and Biology. 22: 905-13. PMID 8547888 DOI: 10.1016/0969-8051(95)00029-W |
0.305 |
|
| 1995 |
Lanier SM, Lanier B, Bakthavachalam V, McGrath CR, Neumeyer JL. Use of high affinity, radioiodinated probes for identification of imidazoline/guanidinium receptive sites. Annals of the New York Academy of Sciences. 763: 106-11. PMID 7677319 DOI: 10.1111/J.1749-6632.1995.Tb32395.X |
0.314 |
|
| 1994 |
Baldessarini RJ, Kula NS, Zong R, Neumeyer JL. Receptor affinities of aporphine enantiomers in rat brain tissue. European Journal of Pharmacology. 254: 199-203. PMID 7911429 DOI: 10.1016/0014-2999(94)90388-3 |
0.433 |
|
| 1994 |
Hashimoto K, Mantione CR, Spada MR, Neumeyer JL, London ED. Further characterization of [3H]ifenprodil binding in rat brain. European Journal of Pharmacology. 266: 67-77. PMID 7907988 DOI: 10.1016/0922-4106(94)90211-9 |
0.307 |
|
| 1994 |
Kula NS, Baldessarini RJ, Kebabian JW, Neumeyer JL. S-(+)-aporphines are not selective for human D3 dopamine receptors. Cellular and Molecular Neurobiology. 14: 185-91. PMID 7842476 DOI: 10.1007/BF02090784 |
0.393 |
|
| 1994 |
Baldessarini RJ, Campbell A, Ben-Jonathan N, Ellingboe J, Zong R, Neumeyer JL. Effects of aporphine isomers on rat prolactin. Neuroscience Letters. 176: 269-71. PMID 7830962 DOI: 10.1016/0304-3940(94)90098-1 |
0.411 |
|
| 1993 |
Jacobson KA, Shi D, Gallo-Rodriguez C, Manning M, Müller C, Daly JW, Neumeyer JL, Kiriasis L, Pfleiderer W. Effect of trifluoromethyl and other substituents on activity of xanthines at adenosine receptors. Journal of Medicinal Chemistry. 36: 2639-44. PMID 8410976 DOI: 10.1021/Jm00070A007 |
0.347 |
|
| 1993 |
Baldwin RM, Zea-Ponce Y, Zoghbi SS, Laurelle M, al-Tikriti MS, Sybirska EH, Malison RT, Neumeyer JL, Milius RA, Wang S. Evaluation of the monoamine uptake site ligand [123I]methyl 3 beta-(4-iodophenyl)-tropane-2 beta-carboxylate ([123I]beta-CIT) in non-human primates: pharmacokinetics, biodistribution and SPECT brain imaging coregistered with MRI. Nuclear Medicine and Biology. 20: 597-606. PMID 8358345 DOI: 10.1016/0969-8051(93)90028-S |
0.308 |
|
| 1993 |
Baldessarini RJ, Kula NS, McGrath CR, Bakthavachalam V, Kebabian JW, Neumeyer JL. Isomeric selectivity at dopamine D3 receptors. European Journal of Pharmacology. 239: 269-70. PMID 8223909 DOI: 10.1016/0014-2999(93)91011-B |
0.418 |
|
| 1993 |
Campbell A, Baldessarini RJ, Neumeyer JL. Altered spontaneous behavior and sensitivity to apomorphine in rats following pretreatment with S(+)-aporphines or fluphenazine. Psychopharmacology. 111: 351-8. PMID 7870974 DOI: 10.1007/BF02244952 |
0.362 |
|
| 1993 |
Laruelle M, Baldwin RM, Malison RT, Zea-Ponce Y, Zoghbi SS, al-Tikriti MS, Sybirska EH, Zimmermann RC, Wisniewski G, Neumeyer JL. SPECT imaging of dopamine and serotonin transporters with [123I]beta-CIT: pharmacological characterization of brain uptake in nonhuman primates. Synapse (New York, N.Y.). 13: 295-309. PMID 7683143 DOI: 10.1002/Syn.890130402 |
0.318 |
|
| 1993 |
Dannals RF, Neumeyer JL, Milius RA, Ravert HT, Wilson AA, Wagner HN. Synthesis of a radiotracer for studying dopamine uptake sites in vivo using PET: 2β-Carbomethoxy-3β-(4-fluorophenyl)-[N-11C-methyl]tropane ([11C]CFT or [11C]WIN-35,428) Journal of Labelled Compounds and Radiopharmaceuticals. 33: 147-152. DOI: 10.1002/jlcr.2580330209 |
0.335 |
|
| 1992 |
Neumeyer JL, Kula NS, Baldessarini RJ, Baindur N. Stereoisomeric probes for the D1 dopamine receptor: synthesis and characterization of R-(+) and S-(-) enantiomers of 3-allyl-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine and its 6-bromo analogue. Journal of Medicinal Chemistry. 35: 1466-71. PMID 1533424 DOI: 10.1021/Jm00086A016 |
0.434 |
|
| 1992 |
Baindur N, Tran M, Niznik HB, Guan HC, Seeman P, Neumeyer JL. (+/-)-3-allyl-7-halo-8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines as selective high affinity D1 dopamine receptor antagonists: synthesis and structure-activity relationship. Journal of Medicinal Chemistry. 35: 67-72. PMID 1531075 DOI: 10.1021/Jm00079A008 |
0.42 |
|
| 1992 |
Neumeyer JL, Baindur N, Bakthavachalam V, Yuan J, Madras BK, Kula NS, Campbell A, Baldessarini RJ. Alan Horn Memorial Lecture. Selective probes for characterization of dopamine D1 and D2 receptors. Neurochemistry International. 20: 63S-68S. PMID 1365458 DOI: 10.1016/0197-0186(92)90212-A |
0.349 |
|
| 1992 |
Neumeyer JL, Baindur N, Bakthavachalam V, Yuan J, Gao Y, Kula NS, Campbell A, Baldessarini RJ. Stereoisomeric, Photoaffinity, Affinity and Fluorescent Probes for Characterization of Dopamine D1 and D2 Receptors Pharmacochemistry Library. 18: 175-184. DOI: 10.1016/B978-0-444-88931-7.50016-5 |
0.378 |
|
| 1991 |
Milius RA, Saha JK, Madras BK, Neumeyer JL. Synthesis and receptor binding of N-substituted tropane derivatives. High-affinity ligands for the cocaine receptor. Journal of Medicinal Chemistry. 34: 1728-31. PMID 2033595 DOI: 10.1021/Jm00109A029 |
0.373 |
|
| 1991 |
Bakthavachalam V, Baindur N, Madras BK, Neumeyer JL. Fluorescent probes for dopamine receptors: synthesis and characterization of fluorescein and 7-nitrobenz-2-oxa-1,3-diazol-4-yl conjugates of D-1 and D-2 receptor ligands. Journal of Medicinal Chemistry. 34: 3235-41. PMID 1956042 DOI: 10.1021/Jm00115A012 |
0.392 |
|
| 1991 |
Neumeyer JL, Baindur N, Niznik HB, Guan HC, Seeman P. (+/-)-3-Allyl-6-bromo-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3- benzazepin, a new high-affinity D1 dopamine receptor ligand: synthesis and structure-activity relationship. Journal of Medicinal Chemistry. 34: 3366-71. PMID 1684995 DOI: 10.1021/Jm00116A004 |
0.44 |
|
| 1991 |
Campbell A, Yeghiayan S, Baldessarini RJ, Neumeyer JL. Selective antidopaminergic effects of S(+)N-n-propylnoraporphines in limbic versus extrapyramidal sites in rat brain: comparisons with typical and atypical antipsychotic agents. Psychopharmacology. 103: 323-9. PMID 1676180 DOI: 10.1007/BF02244285 |
0.393 |
|
| 1991 |
Baldessarini RJ, Kula NS, Gao Y, Campbell A, Neumeyer JL. R(-)2-fluoro-N-n-propylnorapomorphine: a very potent and D2-selective dopamine agonist. Neuropharmacology. 30: 97-9. PMID 1675452 DOI: 10.1016/0028-3908(91)90049-H |
0.428 |
|
| 1991 |
Neumeyer JL, Gao YG, Kula NS, Baldessarini RJ. R and S enantiomers of 11-hydroxy- and 10,11-dihydroxy-N-allylnoraporphine: synthesis and affinity for dopamine receptors in rat brain tissue. Journal of Medicinal Chemistry. 34: 24-8. PMID 1671415 |
0.304 |
|
| 1990 |
Neumeyer JL, Baindur N, Yuan J, Booth G, Seeman P, Niznik HB. Development of a high affinity and stereoselective photoaffinity label for the D-1 dopamine receptor: synthesis and resolution of 7-[125I]iodo-8-hydroxy-3-methyl-1-(4'-azidophenyl)-2,3,4,5-tetrahydro- 1H-3-benzazepine. Journal of Medicinal Chemistry. 33: 521-6. PMID 2405157 DOI: 10.1021/Jm00164A009 |
0.434 |
|
| 1990 |
Baldessarini RJ, Marsh ER, Kula NS, Zong RS, Gao YG, Neumeyer JL. Effects of isomers of hydroxyaporphines on dopamine metabolism in rat brain regions. Biochemical Pharmacology. 40: 417-23. PMID 2383279 DOI: 10.1016/0006-2952(90)90538-V |
0.42 |
|
| 1990 |
Madras BK, Kamien JB, Fahey MA, Canfield DR, Milius RA, Saha JK, Neumeyer JL, Spealman RD. N-modified fluorophenyltropane analogs of cocaine with high affinity for cocaine receptors. Pharmacology, Biochemistry, and Behavior. 35: 949-53. PMID 2345768 DOI: 10.1016/0091-3057(90)90384-T |
0.302 |
|
| 1990 |
Neumeyer JL, Gao YG, Kula NS, Baldessarini RJ. Synthesis and dopamine receptor affinity of (R)-(-)-2-fluoro-N-n-propylnorapomorphine: a highly potent and selective dopamine D2 agonist. Journal of Medicinal Chemistry. 33: 3122-4. PMID 2147956 DOI: 10.1021/Jm00174A002 |
0.355 |
|
| 1990 |
Madras BK, Canfield DR, Pfaelzer C, Vittimberga FJ, Difiglia M, Aronin N, Bakthavachalam V, Baindur N, Neumeyer JL. Fluorescent and biotin probes for dopamine receptors: D1 and D2 receptor affinity and selectivity. Molecular Pharmacology. 37: 833-9. PMID 2141665 |
0.327 |
|
| 1990 |
Gao YG, Ram VJ, Campbell A, Kula NS, Baldessarini RJ, Neumeyer JL. Synthesis and structural requirements of N-substituted norapomorphines for affinity and activity at dopamine D-1, D-2, and agonist receptor sites in rat brain. Journal of Medicinal Chemistry. 33: 39-44. PMID 2136919 DOI: 10.1021/Jm00163A007 |
0.464 |
|
| 1990 |
Campbell A, Baldessarini RJ, Gao Y, Zong R, Neumeyer JL. R(-) and S(+) stereoisomers of 11-hydroxy- and 11-methoxy-N-n-propylnoraporphine: central dopaminergic behavioral activity in the rat. Neuropharmacology. 29: 527-36. PMID 1974710 DOI: 10.1016/0028-3908(90)90064-X |
0.371 |
|
| 1990 |
Gao YG, Baldessarini RJ, Kula NS, Neumeyer JL. Synthesis and dopamine receptor affinities of enantiomers of 2-substituted apomorphines and their N-n-propyl analogues. Journal of Medicinal Chemistry. 33: 1800-5. PMID 1971309 DOI: 10.1021/Jm00168A040 |
0.342 |
|
| 1990 |
Booth RG, Baldessarini RJ, Kula NS, Neumeyer JL. Stereochemical effects of mono- and dihydroxyaporphines on presynaptic inhibition of dopamine synthesis in vitro Annals of the New York Academy of Sciences. 604: 592-595. DOI: 10.1111/j.1749-6632.1990.tb32034.x |
0.347 |
|
| 1990 |
Neumeyer JL, Bakthavachalam V, Yuan J, Kula NS, Campbell A, Baldessarini RJ. Irreversible ligands for dopamine D-2 receptors European Journal of Pharmacology. 183: 745-746. DOI: 10.1016/0014-2999(90)92546-U |
0.39 |
|
| 1989 |
Jacobson KA, Kiriasis L, Barone S, Bradbury BJ, Kammula U, Campagne JM, Secunda S, Daly JW, Neumeyer JL, Pfleiderer W. Sulfur-containing 1,3-dialkylxanthine derivatives as selective antagonists at A1-adenosine receptors. Journal of Medicinal Chemistry. 32: 1873-9. PMID 2754711 DOI: 10.1021/Jm00128A031 |
0.361 |
|
| 1989 |
Ramsby S, Neumeyer JL, Grigoriadis D, Seeman P. 2-Haloaporphines as potent dopamine agonists. Journal of Medicinal Chemistry. 32: 1198-201. PMID 2524592 DOI: 10.1021/Jm00126A009 |
0.426 |
|
| 1988 |
Lampen P, Neumeyer JL, Baldessarini RJ. High-performance liquid chromatographic separation and electrochemical or spectrophotometric determination of R(-)N-n-propylnorapomorphine and R(-)10,11-methylenedioxy-N-n-propylnoraporphine in primate plasma. Journal of Chromatography. 426: 283-94. PMID 3392141 DOI: 10.1016/S0378-4347(00)81956-8 |
0.344 |
|
| 1988 |
Gao Y, Zong R, Campbell A, Kula NS, Baldessarini RJ, Neumeyer JL. Synthesis and dopamine agonist and antagonist effects of (R)-(-)- and (S)-(+)-11-hydroxy-N-n-propylnoraporphine. Journal of Medicinal Chemistry. 31: 1392-6. PMID 3385732 DOI: 10.1021/Jm00402A024 |
0.412 |
|
| 1988 |
Baindur N, Neumeyer JL, Niznik HB, Bzowej NH, Jarvie KR, Seeman P, Garlick RK, Miller JJ. A photoaffinity label for the D-1 dopamine receptor, (RS)-7-[125I]Iodo-8-hydroxy-3-methyl-1-(4'-azidophenyl)-2,3,4,5- tetrahydro-1H-3-benzazepine, selectively identifies the ligand binding subunits of the receptor. Journal of Medicinal Chemistry. 31: 2069-71. PMID 3263503 DOI: 10.1021/Jm00119A003 |
0.397 |
|
| 1988 |
Niznik HB, Jarvie KR, Bzowej NH, Seeman P, Garlick RK, Miller JJ, Baindur N, Neumeyer JL. Photoaffinity labeling of dopamine D1 receptors. Biochemistry. 27: 7594-9. PMID 3207691 DOI: 10.1021/Bi00420A004 |
0.348 |
|
| 1988 |
Jacobson KA, de la Cruz R, Schulick R, Kiriasis L, Padgett W, Pfleiderer W, Kirk KL, Neumeyer JL, Daly JW. 8-Substituted xanthines as antagonists at A1- and A2-adenosine receptors. Biochemical Pharmacology. 37: 3653-61. PMID 3178879 DOI: 10.1016/0006-2952(88)90398-X |
0.371 |
|
| 1988 |
Gao Y, Trainor TM, Vouros P, Neumeyer JL. The synthesis of multiple deuterated N-n-propylnorapomorphine N-(d7) and derivatives Journal of Labelled Compounds and Radiopharmaceuticals. 25: 293-299. DOI: 10.1002/Jlcr.2580250309 |
0.353 |
|
| 1987 |
Campbell A, Baldessarini RJ, Kula NS, Ram VJ, Neumeyer JL. S(+)methylenedioxy-N-n-propylnoraporphine: an orally active inhibitor of dopamine selective for rat limbic system. Brain Research. 403: 393-7. PMID 3828830 DOI: 10.1016/0006-8993(87)90083-7 |
0.425 |
|
| 1986 |
Froimowitz M, Neumeyer JL, Baldessarini RJ. A stereochemical explanation of the dopamine agonist and antagonist activity of stereoisomeric pairs. Journal of Medicinal Chemistry. 29: 1570-3. PMID 3746808 DOI: 10.1021/Jm00159A002 |
0.382 |
|
| 1986 |
Baldessarini RJ, Kula NS, Francoeur D, Finklestein SP, Murphy F, Neumeyer JL. Synthetic analgesics and other phenylpiperidines: effects on uptake and storage of dopamine and other monoamines mouse forebrain tissue. Life Sciences. 39: 1765-77. PMID 3490612 DOI: 10.1016/0024-3205(86)90096-2 |
0.406 |
|
| 1986 |
Campbell A, Baldessarini RJ, Teicher MH, Neumeyer JL. Behavioral effects of apomorphine isomers in the rat: selective locomotor-inhibitory effects of S(+)N-n-propylnorapomorphine. Psychopharmacology. 88: 158-64. PMID 3081927 DOI: 10.1007/BF00652233 |
0.346 |
|
| 1986 |
Neumeyer JL, Abdel-Maksoud HM, Trainor TM, Vouros P, Davis PJ. Aporphines 65: chemical, microbial synthesis and characterization by gas chromatography/mass spectrometry of (R)-(-)-10-hydroxy 11-methoxy-N-n-propylnoraporphine, a potential metabolite of N-n-propylnorapomorphine. Biomedical & Environmental Mass Spectrometry. 13: 223-9. PMID 2941089 DOI: 10.1002/Bms.1200130504 |
0.337 |
|
| 1985 |
Kula NS, Baldessarini RJ, Bromley S, Neumeyer JL. Effects of isomers of apomorphines on dopamine receptors in striatal and limbic tissue of rat brain. Life Sciences. 37: 1051-7. PMID 4033350 DOI: 10.1016/0024-3205(85)90596-X |
0.419 |
|
| 1985 |
Campbell A, Baldessarini RJ, Teicher MH, Neumeyer JL. S(+)Apomorphines. Selective inhibition of excitatory effects of dopamine injected into the limbic system of the rat. Neuropharmacology. 24: 391-9. PMID 4022264 DOI: 10.1016/0028-3908(85)90023-1 |
0.379 |
|
| 1985 |
Davis PJ, Abdel-Maksoud H, Trainor TM, Vouros P, Neumeyer JL. Stereospecific microbiological 10-O-demethylation of R-(-)-10,11-dimethoxyaporphines. Biochemical and Biophysical Research Communications. 127: 407-12. PMID 3838476 DOI: 10.1016/S0006-291X(85)80175-3 |
0.309 |
|
| 1985 |
Niznik HB, Dumbrille-Ross A, Guan JH, Neumeyer JL, Seeman P. Dopamine D2 receptors photolabeled by iodo-azido-clebopride. Neuroscience Letters. 55: 267-72. PMID 3159976 DOI: 10.1016/0304-3940(85)90446-X |
0.418 |
|
| 1985 |
Neumeyer JL, Guan JH, Niznik HB, Dumbrille-Ross A, Seeman P, Padmanabhan S, Elmaleh DR. Novel photoaffinity label for the dopamine D2 receptor: synthesis of 4-azido-5-iodo-2-methoxy-N-[1-(phenylmethyl)-4-piperidinyl] benzamide (iodoazidoclebopride, IAC) and the corresponding 125I-labeled analogue (125IAC). Journal of Medicinal Chemistry. 28: 405-7. PMID 3156993 DOI: 10.1021/Jm00382A002 |
0.655 |
|
| 1984 |
Guan JH, Neumeyer JL, Filer CN, Ahern DG, Lilly L, Watanabe M, Grigoriadis D, Seeman P. Aporphines. 58. N-(2-chloroethyl) [8,9-2H]norapomorphine, an irreversible ligand for dopamine receptors: synthesis and application. Journal of Medicinal Chemistry. 27: 806-10. PMID 6737423 DOI: 10.1021/Jm00372A019 |
0.402 |
|
| 1984 |
Kula NS, Baldessarini RJ, Campbell A, Finklestein S, Ram VJ, Neumeyer JL. Effects of N-substituted phenyltetrahydropyridines on cerebral high-affinity synaptosomal uptake of dopamine and other monoamines in several mammalian species. Life Sciences. 34: 2567-75. PMID 6610812 DOI: 10.1016/0024-3205(84)90042-0 |
0.396 |
|
| 1984 |
Niznik HB, Guan JH, Neumeyer JL, Seeman P. A dopamine D2 receptor photolabel: azidoclebopride. European Journal of Pharmacology. 104: 389-90. PMID 6499931 DOI: 10.1016/0014-2999(84)90420-5 |
0.391 |
|
| 1984 |
Arana GW, Lamont JS, Baldessarini RJ, Teicher MH, Neumeyer JL, Cohen BM. Binding of [3H]apomorphine to an aporphine binding site as well as to dopamine sites in tissue from bovine caudate nucleus. Neuropharmacology. 23: 885-92. PMID 6483116 DOI: 10.1016/0028-3908(84)90001-7 |
0.346 |
|
| 1984 |
Schmidt M, Imbs JL, Neumeyer JL, Giesen EM, Schwartz J. Vascular effects of apomorphine and related compounds in the perfused rat kidney. European Journal of Pharmacology. 97: 75-85. PMID 6141949 DOI: 10.1016/0014-2999(84)90514-4 |
0.306 |
|
| 1984 |
Hjorth S, Neumeyer JL. Central monoaminergic effects of two aporphine analogues to the putative serotonin-receptor agonist, 8-hydroxy-2-di-n-propylaminotetralin. Neuropharmacology. 23: 1187-90. PMID 6097834 DOI: 10.1016/0028-3908(84)90237-5 |
0.405 |
|
| 1984 |
Guan J‐, Neumeyer JL, Filer CN, Ahern DG, Lilly L, Watanabe M, Grigoriadis D, Seeman P. Aporphines. 58. N‐(2‐Chloroethyl)(8,9‐2H)Norapomorphine, An Irreversible Ligand For Dopamine Receptors: Synthesis And Application Cheminform. 15. DOI: 10.1002/Chin.198444332 |
0.386 |
|
| 1983 |
Maksoud HM, Kuttab SH, Neumeyer JL, Vouros P. Analysis of N-n-propylnorapomorphine in plasma and tissue by capillary gas chromatography--electron-capture detection. Journal of Chromatography. 274: 149-59. PMID 6874818 DOI: 10.1016/S0378-4347(00)84418-7 |
0.333 |
|
| 1983 |
Neumeyer JL, Szabo S. (-)-10,11-Methylenedioxy-N-propylnoraporphine, an orally effective dopamine agonist and duodenal antiulcerogen in the rat. European Journal of Pharmacology. 88: 273-4. PMID 6852114 DOI: 10.1016/0014-2999(83)90018-3 |
0.388 |
|
| 1983 |
Neumeyer JL, Reischig D, Arana GW, Campbell A, Baldessarini RJ, Kula NS, Watling KJ. Aporphines. 48. Enantioselectivity of (R)-(-)- and (S)-(+)-N-n-propylnorapomorphine on dopamine receptors. Journal of Medicinal Chemistry. 26: 516-21. PMID 6682147 DOI: 10.1021/Jm00358A011 |
0.416 |
|
| 1983 |
Arana GW, Baldessarini RJ, Lamont JS, Amlicke D, Neumeyer JL. Pharmacology of high-affinity binding of [3H](+/-)2-amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (ADTN) to bovine caudate nucleus tissue. Biochemical Pharmacology. 32: 2873-80. PMID 6626260 DOI: 10.1016/0006-2952(83)90391-X |
0.378 |
|
| 1983 |
Anlezark GM, Blackwood DH, Meldrum BS, Ram VJ, Neumeyer JL. Comparative assessment of dopamine agonist aporphines as anticonvulsants in two models of reflex epilepsy. Psychopharmacology. 81: 135-9. PMID 6415743 DOI: 10.1007/BF00429007 |
0.327 |
|
| 1983 |
Jackson EA, Neumeyer JL, Kelly PH. Behavioral activity of some novel aporphines in rats with 6-hydroxydopamine lesions of caudate or nucleus accumbens. European Journal of Pharmacology. 87: 15-23. PMID 6404639 DOI: 10.1016/0014-2999(83)90045-6 |
0.362 |
|
| 1983 |
Bradbury AJ, Costall B, Naylor RJ, Neumeyer JL. Motor inhibition induced by aporphine derivatives in the mouse. The Journal of Pharmacy and Pharmacology. 35: 494-9. PMID 6137533 DOI: 10.1111/J.2042-7158.1983.Tb04817.X |
0.36 |
|
| 1982 |
Neumeyer JL, Arana GW, Ram VJ, Kula NS, Baldessarini RJ. Aporphines. 39. Synthesis, dopamine receptor binding, and pharmacological activity of (R)-(-)- and (S)-(+)-2-hydroxyapomorphine. Journal of Medicinal Chemistry. 25: 990-2. PMID 7120288 DOI: 10.1021/Jm00350A021 |
0.406 |
|
| 1982 |
Sperk G, Campbell A, Baldessarini RJ, Stoll A, Neumeyer JL. Tissue levels of N-n-propylnorapomorphine after treatment with (-)10,11-methylenedioxy-N-n-propylnoraporphine, an orally long-acting prodrug active at central dopamine receptors. Neuropharmacology. 21: 1311-6. PMID 6891445 DOI: 10.1016/0277-5379(82)90104-3 |
0.398 |
|
| 1982 |
Campbell A, Baldessarini RJ, Ram VJ, Neumeyer JL. Behavioral effects of (-)10,11-methylenedioxy-N-n-propylnoraporphine, an orally effective long-acting agent active at central dopamine receptors, and analogous aporphines. Neuropharmacology. 21: 953-61. PMID 6890636 DOI: 10.1016/0028-3908(82)90106-X |
0.352 |
|
| 1982 |
Baldessarini RJ, Neumeyer JL, Campbell A, Sperk G, Ram VJ, Arana GW, Kula NS. An orally effective, long-acting dopaminergic prodrug: (-)-10,11-methylenedioxy-N-propylnoraporphine. European Journal of Pharmacology. 77: 87-8. PMID 6277658 DOI: 10.1016/0014-2999(82)90543-X |
0.317 |
|
| 1981 |
Neumeyer JL, Arana GW, Law SJ, Lamont JS, Kula NS, Baldessarini RJ. Aporphines, 36. Dopamine receptor interactions of trihydroxyaporphines. Synthesis, radioreceptor binding, and striatal adenylate cyclase stimulation of 2,10,11-trihydroxyaporphines in comparison with other hydroxylated aporphines. Journal of Medicinal Chemistry. 24: 1440-5. PMID 7310821 DOI: 10.1021/Jm00144A014 |
0.386 |
|
| 1981 |
Neumeyer JL, Law SJ, Meldrum B, Anlezark G, Watling KJ. Aporphines. 34. (-)-2,10,11-Trihydroxy-N-n-propylnoraporphine, a novel dopaminergic aporphine alkaloid with anticonvulsant activity. Journal of Medicinal Chemistry. 24: 898-9. PMID 7277402 DOI: 10.1021/JM00139A027 |
0.354 |
|
| 1980 |
Baldessarini RJ, Kula NS, Arana GW, Neumeyer JL, Law SJ. Chloroethylnorapomorphine, a proposed long-acting dopamine antagonist: interactions with dopamine receptors of mammalian forebrain in vitro. European Journal of Pharmacology. 67: 105-10. PMID 7418727 DOI: 10.1016/0014-2999(80)90015-1 |
0.396 |
|
| 1980 |
Neumeyer JL, Granchelli FE, Filer CN, Soloway AH, Law SJ. Aporphines. 31. Synthesis and antitumor activity of aporphine nitrogen mustards. Journal of Medicinal Chemistry. 23: 1008-13. PMID 7411543 DOI: 10.1021/Jm00183A009 |
0.37 |
|
| 1980 |
Costall B, Fortune DH, Law SJ, Naylor RJ, Neumeyer JL, Nohria V. (-)N-(chloroethyl)norapomorphine inhibits striatal dopamine function via irreversible receptor binding. Nature. 285: 571-3. PMID 7402299 DOI: 10.1038/285571a0 |
0.439 |
|
| 1980 |
Neumeyer JL, Law SJ, Baldessarini RJ, Kula NS. Aporphines. 30. (-)-N(2-chloroethyl)-10,11-dihydroxynor-aporphine (chloroethylnorapomorphine), a novel irreversible dopamine receptor antagonist. Journal of Medicinal Chemistry. 23: 594-5. PMID 7392026 DOI: 10.1021/Jm00180A002 |
0.437 |
|
| 1980 |
Costall B, Fortune DH, Granchelli FE, Law SJ, Naylor RJ, Neumeyer JL, Nohria V. On the ability of N-chloroethyl aporphine derivatives to cause irreversible inhibition of dopamine receptor mechanisms. The Journal of Pharmacy and Pharmacology. 32: 571-6. PMID 6106696 DOI: 10.1111/J.2042-7158.1980.Tb12999.X |
0.413 |
|
| 1980 |
Granchelli FE, Filer CN, Soloway AH, Neumeyer JL. Aporphines. 27. Mechanistic aspects of the rearrangement of thebaine and codeine analogs in methanesulfonic acid. Improved method for the synthesis of N-alkylated aporphines Journal of Organic Chemistry. 45: 2275-2278. DOI: 10.1021/Jo01300A001 |
0.32 |
|
| 1980 |
Granchelli FE, Filer CN, Soloway AH, Neumeyer JL. Aporphines. 27. Mechanistic aspects of the rearrangement of thebaine and codeine analogs in methanesulfonic acid. Improved method for the synthesis of N-alkylated aporphines Cheminform. 11. DOI: 10.1002/Chin.198043310 |
0.32 |
|
| 1979 |
Green JF, Evans JV, Neumeyer JL, Vouros P. Aporphines. 25-trimethylislyl derivatives of N-methyl and N-propyl aporphines: gas chromatographic and mass spectrometric properties. Biomedical Mass Spectrometry. 6: 282-6. PMID 486713 DOI: 10.1002/Bms.1200060704 |
0.301 |
|
| 1979 |
Elmaleh DR, and FEG, Neumeyer JL. Aporphines 24. The synthesis of N-alkylderivatives of bulbocapnine and isoeorydine Journal of Heterocyclic Chemistry. 16: 87-92. DOI: 10.1002/Jhet.5570160118 |
0.313 |
|
| 1979 |
Elmaleh DR, Granchelli FE, Neumeyer JL. Aporphines 24. The Synthesis Of N-Alkyl Derivatives Of Bulbocapnine And Isocorydine Cheminform. 10. DOI: 10.1002/Chin.197930373 |
0.356 |
|
| 1978 |
Menon MK, Clark WG, Neumeyer JL. Comparison of the dopaminergic effects of apomorphine and (-)-N-n-propylnorapomorphine. European Journal of Pharmacology. 52: 1-9. PMID 569056 DOI: 10.1016/0014-2999(78)90015-8 |
0.38 |
|
| 1977 |
Neumeyer JL, Uretsky NJ, Charest RR. Effects of (+/-)-10-hydroxy-N-n-propylnoraporphine on catecholamine turnover in the rat brain. The Journal of Pharmacy and Pharmacology. 29: 179-81. PMID 15086 DOI: 10.1111/J.2042-7158.1977.Tb11280.X |
0.319 |
|
| 1977 |
Neumeyer JL, Dafeldecker WP, Costall B, Naylor RJ. Aporphines. 21. Dopaminergic Activity Of Aporphine And Benzylisoquinoline Derivatives. Synthesis Of 8-Hydroxyaporphines And 1-(Hydroxybenzyl)-2-N-Propyl-1,2,3,4-Tetrahydroisoquinolines Cheminform. 8. DOI: 10.1002/Chin.197727224 |
0.38 |
|
| 1976 |
Kelly PH, Miller RJ, Neumeyer JL. Aporphines. 16. Action of aporphine alkaloids on locomotor activity in rats with 6-hydroxydopamine lesions of the nucleus accumbens. European Journal of Pharmacology. 35: 85-92. PMID 1253829 DOI: 10.1016/0014-2999(76)90303-4 |
0.311 |
|
| 1976 |
Miller RJ, Kelly PH, Neumeyer JL. Aporphines. 15. Action of aporphine alkaloids on dopaminergic mechanisms in rat brain. European Journal of Pharmacology. 35: 77-83. PMID 943290 DOI: 10.1016/0014-2999(76)90302-2 |
0.365 |
|
| 1976 |
Neumeyer JL, Reinhard JF, Dafeldecker WP, Guarino J, Kosersky DS, Fuxe K, Agnati L. Aporphines. 14 Dopaminergic and antinociceptive activity of aporphine derivatives. Synthesis of 10-hydroxyaporphines and 10-hydroxy-N-n-propylnoraporphine. Journal of Medicinal Chemistry. 19: 25-9. PMID 942751 DOI: 10.1021/Jm00223A006 |
0.377 |
|
| 1975 |
Costall B, Naylor RJ, Neumeyer JL. Differences in the nature of the stereotyped behaviour induced by aporphine derivatives in the rat and in their actions in extrapyramidal and mesolimbic brain areas. European Journal of Pharmacology. 31: 1-16. PMID 1168579 DOI: 10.1016/0014-2999(75)90072-2 |
0.312 |
|
| 1975 |
Schoenfeld RI, Neumeyer JL, Dafeldecker W, Roffler-Tarlov S. Comparison of structural and stereoisomers of apomorphine on stereotyped behavior of the rat. European Journal of Pharmacology. 30: 63-8. PMID 1168137 DOI: 10.1016/0014-2999(75)90203-4 |
0.352 |
|
| 1975 |
NEUMEYER JL, GRANCHELLI FE, FUXE K, UNGERSTEDT U, CORRODI H. ChemInform Abstract: APORPHINES PART 11, SYNTHESIS AND DOPAMINERGIC ACTIVITY OF MONOHYDROXYPORPHINES, TOTAL SYNTHESIS OF (+-)-11-HYDROXYPORPHINE, (+-)-11-HYDROXYNORAPORPHINE, AND (+-)-11-HYDROXY-N-N-PROPYLNORAPORPHINE Chemischer Informationsdienst. 6: no-no. DOI: 10.1002/CHIN.197505434 |
0.368 |
|
| 1973 |
Neumeyer JL, Neustadt BR, Oh KH, Weinhardt KK, Boyce CB, Rosenberg FJ, Teiger DG. Aporphines. 8. Total synthesis and pharmacological evaluation of (plus or minus)-apomorphine, (plus or minus)-apocodeine, (plus or minus)-N-n-propylnorapomorphine, and (plus or minus)-N-n-propylnorapocodeine. Journal of Medicinal Chemistry. 16: 1223-8. PMID 4201182 DOI: 10.1021/jm00269a601 |
0.331 |
|
| 1964 |
NEUMEYER JL. CONVENIENT SYNTHESIS OF N,N,N'-TRISUBSTITUTED FORMAMIDINES. Journal of Pharmaceutical Sciences. 53: 1539-40. PMID 14255143 DOI: 10.1002/Jps.2600531228 |
0.324 |
|
| 1964 |
NEUMEYER JL. FACILE SYNTHESIS OF ISOINDOLINE AND SUBSTITUTED ISOINDOLINES. Journal of Pharmaceutical Sciences. 53: 981-2. PMID 14244109 DOI: 10.1002/Jps.2600530840 |
0.35 |
|
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